Weight in grams of the tibialis anterior (TA), the main muscle responsible for dorsiflexion and inversion of the foot
Tags: Physiology · Muscle
Project: lionikas_2014
27 loci · 87 genes with independent associations · 1625 total associated genes
# | Chr | Start pos | End pos | # assoc genes | # joint models | Best TWAS P | Best GWAS P | Cond GWAS P | Joint genes |
---|---|---|---|---|---|---|---|---|---|
1 | chr1 | 7254793 | 8653308 | 3 | 1 | 1.65e-07 | 6.55e-08 | 1.00e+00 | Adat2 |
2 | chr1 | 171727837 | 174981149 | 28 | 3 | 2.19e-08 | 1.78e-08 | 1.00e+00 | Gde1 Knop1 LOC102551259 |
3 | chr1 | 176132720 | 178728015 | 11 | 1 | 1.07e-08 | 1.01e-08 | 1.00e+00 | Tnrc6a |
4 | chr1 | 199748697 | 208229833 | 628 | 7 | 4.47e-13 | 1.13e-11 | 1.00e+00 | Dpf2 Fam89b Ppp6r3 Prdx5 Rbm4 Sdhaf2 Znrd2 |
5 | chr2 | 90475129 | 95173253 | 34 | 1 | 3.55e-12 | 7.14e-12 | 1.00e+00 | Mrps28 |
6 | chr2 | 99787494 | 102351095 | 3 | 1 | 1.85e-07 | 8.17e-08 | 8.44e-02 | Bhlhe22 |
7 | chr2 | 117887529 | 120309104 | 26 | 1 | 1.63e-08 | 1.47e-08 | 1.00e+00 | Mccc1 |
8 | chr2 | 120425440 | 122626616 | 5 | 1 | 1.01e-07 | 1.12e-08 | 3.31e-02 | Fat4 |
9 | chr2 | 123236866 | 124634730 | 1 | 1 | 1.18e-07 | 1.22e-06 | 1.00e+00 | Larp1b |
10 | chr2 | 225664331 | 228461478 | 14 | 1 | 1.44e-10 | 1.67e-10 | 4.63e-02 | LOC102555623 |
11 | chr5 | 48482122 | 49968409 | 19 | 3 | 2.33e-08 | 2.33e-08 | 1.00e+00 | LOC102557269 RGD1359108 |
12 | chr5 | 54563228 | 59007126 | 115 | 7 | 3.32e-10 | 2.67e-10 | 1.00e+00 | Gba2 LOC103692336 LOC120102855 Phf24 Reck Rig1 |
13 | chr5 | 110713361 | 115818093 | 120 | 9 | 3.72e-09 | 1.19e-08 | 1.00e+00 | Alg6 C5h1orf87 Itgb3bp Kank4 LOC102556219 Ube2u |
14 | chr6 | 19297402 | 21124468 | 9 | 1 | 7.42e-10 | 3.91e-10 | 1.18e-01 | Rasgrp3 |
15 | chr6 | 51058548 | 53588284 | 5 | 1 | 1.30e-08 | 7.65e-08 | 4.75e-01 | LOC102554773 |
16 | chr6 | 96850756 | 98793722 | 5 | 3 | 9.73e-08 | 4.44e-07 | 5.48e-03 | Pals1 Pigh Zfyve26 |
17 | chr7 | 84902790 | 86293354 | 1 | 1 | 2.07e-07 | 1.03e-07 | 1.54e-02 | Tnfrsf11b |
18 | chr7 | 130737419 | 133838246 | 88 | 6 | 1.39e-11 | 1.34e-10 | 1.00e+00 | Atg101 Igfbp6 Pou6f1 Tamalin Tfcp2 |
19 | chr8 | 69362619 | 75537324 | 119 | 12 | 1.02e-13 | 4.13e-13 | NaN | Aqp9 Bnip2 Ccpg1 Cgnl1 LOC103693140 LOC120094195 Myzap Nedd4 Pigb Prtg Zfp280d |
20 | chr10 | 58773413 | 61528656 | 60 | 4 | 5.84e-11 | 1.49e-10 | 1.00e+00 | Crk Rtn4rl1 Slc43a2 Smyd4 |
21 | chr11 | 25981460 | 27379908 | 1 | 1 | 1.96e-07 | 8.06e-07 | 9.17e-02 | Usp16 |
22 | chr11 | 32161467 | 35008541 | 60 | 5 | 1.61e-09 | 2.59e-09 | 1.00e+00 | LOC120095637 Morc3 Setd4 Vps26c |
23 | chr12 | 22091 | 4653252 | 80 | 4 | 9.73e-10 | 2.41e-08 | NaN | Snapc2 Stxbp2 Trappc5 Zfp958 |
24 | chr12 | 11263108 | 12661472 | 1 | 1 | 1.23e-07 | 7.08e-08 | 1.69e-01 | Mmd2 |
25 | chr15 | 35841493 | 43041493 | 75 | 7 | 5.58e-09 | 5.35e-09 | 1.00e+00 | Adra1a Extl3 Fam124a Prss52 Ptk2b Scara5 Stmn4 |
26 | chr15 | 43602320 | 46417324 | 113 | 3 | 1.08e-11 | 3.72e-08 | 1.00e+00 | Fhip2b Phyhip Sorbs3 |
27 | chr20 | 53722628 | 54429288 | 1 | 1 | 2.53e-10 | 5.20e-01 | 1.00e+00 | LOC103694460 |
Tissue | RNA modality | # hits | % hits/tests | Avg chisq |
---|---|---|---|---|
Adipose | alternative polyA | 55 | 1.5 | 3.54 |
Adipose | alternative TSS | 39 | 1.2 | 3.13 |
Adipose | gene expression | 128 | 1.4 | 3.48 |
Adipose | isoform ratio | 62 | 1.3 | 3.4 |
Adipose | intron excision ratio | 25 | 0.8 | 2.93 |
Adipose | mRNA stability | 58 | 1.3 | 3.42 |
BLA | alternative polyA | 37 | 1.7 | 3.46 |
BLA | alternative TSS | 35 | 1.9 | 3.66 |
BLA | gene expression | 118 | 1.8 | 3.55 |
BLA | isoform ratio | 60 | 2 | 3.57 |
BLA | intron excision ratio | 44 | 1.3 | 3.13 |
BLA | mRNA stability | 37 | 1.5 | 3.58 |
Brain | alternative polyA | 57 | 1.5 | 3.37 |
Brain | alternative TSS | 77 | 1.9 | 3.57 |
Brain | gene expression | 165 | 1.6 | 3.49 |
Brain | isoform ratio | 106 | 1.9 | 3.55 |
Brain | intron excision ratio | 94 | 1.6 | 3.31 |
Brain | mRNA stability | 86 | 1.6 | 3.51 |
Eye | alternative polyA | 2 | 0.7 | 3.15 |
Eye | alternative TSS | 5 | 1.3 | 3.61 |
Eye | gene expression | 23 | 1.9 | 3.6 |
Eye | isoform ratio | 7 | 1.2 | 3.35 |
Eye | intron excision ratio | 21 | 2.3 | 3.41 |
Eye | mRNA stability | 7 | 1.9 | 3.51 |
IL | alternative polyA | 24 | 2.2 | 3.67 |
IL | alternative TSS | 10 | 1.5 | 3.24 |
IL | gene expression | 63 | 1.5 | 3.37 |
IL | isoform ratio | 23 | 1.8 | 3.47 |
IL | intron excision ratio | 18 | 1.6 | 3.25 |
IL | mRNA stability | 25 | 1.8 | 3.55 |
LHb | alternative polyA | 26 | 2.3 | 3.63 |
LHb | alternative TSS | 6 | 1 | 2.87 |
LHb | gene expression | 59 | 1.6 | 3.45 |
LHb | isoform ratio | 20 | 1.6 | 3.53 |
LHb | intron excision ratio | 13 | 1.1 | 2.74 |
LHb | mRNA stability | 17 | 1.3 | 3.48 |
Liver | alternative polyA | 36 | 1.4 | 3.36 |
Liver | alternative TSS | 36 | 1.4 | 3.15 |
Liver | gene expression | 112 | 1.4 | 3.34 |
Liver | isoform ratio | 52 | 1.4 | 3.33 |
Liver | intron excision ratio | 52 | 1.1 | 3.21 |
Liver | mRNA stability | 43 | 1.4 | 3.42 |
NAcc | alternative polyA | 67 | 2.2 | 3.59 |
NAcc | alternative TSS | 42 | 1.5 | 3.38 |
NAcc | gene expression | 159 | 1.9 | 3.54 |
NAcc | isoform ratio | 76 | 1.8 | 3.51 |
NAcc | intron excision ratio | 76 | 1.5 | 3.39 |
NAcc | mRNA stability | 60 | 1.8 | 3.61 |
OFC | alternative polyA | 16 | 1.4 | 3.11 |
OFC | alternative TSS | 11 | 1.5 | 3.24 |
OFC | gene expression | 74 | 1.8 | 3.5 |
OFC | isoform ratio | 23 | 1.7 | 3.46 |
OFC | intron excision ratio | 24 | 2.1 | 3.38 |
OFC | mRNA stability | 16 | 1.2 | 3.34 |
PL | alternative polyA | 41 | 1.2 | 3.38 |
PL | alternative TSS | 64 | 1.9 | 3.49 |
PL | gene expression | 152 | 1.6 | 3.47 |
PL | isoform ratio | 93 | 2 | 3.57 |
PL | intron excision ratio | 77 | 1.4 | 3.27 |
PL | mRNA stability | 76 | 2 | 3.6 |
pVTA | alternative polyA | 25 | 1.5 | 3.46 |
pVTA | alternative TSS | 17 | 1.3 | 3.44 |
pVTA | gene expression | 91 | 1.7 | 3.49 |
pVTA | isoform ratio | 48 | 2.1 | 3.55 |
pVTA | intron excision ratio | 53 | 1.8 | 3.24 |
pVTA | mRNA stability | 26 | 1.8 | 3.54 |
RMTg | alternative polyA | 8 | 1.4 | 3.24 |
RMTg | alternative TSS | 2 | 0.4 | 2.84 |
RMTg | gene expression | 29 | 1.6 | 3.67 |
RMTg | isoform ratio | 6 | 0.9 | 2.95 |
RMTg | intron excision ratio | 19 | 2.3 | 3.41 |
RMTg | mRNA stability | 11 | 1.8 | 3.75 |