Best TWAS P=1.056429e-07 · Best GWAS P=1.027964e-07 conditioned to 0.03012278
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | OFC | NA | intron excision ratio | chr7:84967032:85057234 | 0.3 | 0.12 | top1 | 1 | 0.12 | 0.00092 | -5.3 | 5.3 | 1.1e-07 | -0.72 | 0.12 | 0.06 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.