Lrrn4cl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	PL	gene expression	Lrrn4cl	0.02	0.02	2.5e-03	0.03	0.03	0.03	0.02	1.9e-04	8.9e-04	8.7e-04	4.6e-03
2	NAcc	gene expression	Lrrn4cl	0.02	0.01	7.9e-03	0.02	0.01	0.01	0.01	3.8e-03	6.9e-03	2.6e-02	8.2e-03
3	Adipose	intron excision ratio	chr1_205749477_205758646	0.04	0.03	5.2e-03	0.01	0.01	0.01	0.01	1.4e-02	2.5e-02	1.3e-02	2.5e-02
4	Brain	isoform ratio	XM_006231002.3	0.02	0.02	9.5e-03	0.02	0.02	0.01	0.02	2.6e-03	7.1e-03	3.9e-02	9.2e-03
5	Adipose	intron excision ratio	chr1_205746703_205758646	0.15	0.07	1.9e-11	0.08	0.1	0.1	0.1	1.8e-09	9.2e-11	1.0e-10	6.5e-11
6	Adipose	intron excision ratio	chr1_205746703_205749399	0.04	0.03	1.5e-03	0.01	0.02	0.02	0.01	5.5e-02	6.3e-03	5.4e-03	1.8e-02
7	Adipose	gene expression	Lrrn4cl	0.07	0.05	8.9e-07	0.04	0.04	0.04	0.04	8.6e-06	1.6e-05	4.9e-05	4.5e-05
8	Adipose	intron excision ratio	chr1_205758779_205765430	0.09	0.05	1.8e-05	0.04	0.04	0.03	0.04	1.5e-05	2.8e-05	1.2e-04	2.4e-05
9	Adipose	intron excision ratio	chr1_205765344_205765430	0.16	0.08	6.5e-10	0.03	0.06	0.05	0.05	5.1e-04	2.1e-07	3.2e-06	2.7e-06
10	Adipose	alternative polyA	XM_006231002.3	0.05	0.03	3.1e-03	0.01	0.01	0.01	0.01	1.6e-02	1.1e-02	3.3e-02	9.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.3	0.4	1.9	-0.6	-0.5	0.6	0.6	0.8	1.4	-0.4	-0.3	-0.5	-0.2
Area under the delay curve	0.2	0.2	0.5	-0.1	-0.0	-0.6	0.1	-0.4	0.2	-0.4	0.7	0.3	0.7
BMI with tail	1.4	4.7	11.5	-2.7	-2.8	1.7	2.6	1.5	3.4	-2.8	0.1	-0.2	0.5
BMI without tail	0.6	1.3	3.3	-1.5	-1.5	0.0	1.4	-0.1	0.9	-1.8	0.8	0.7	1.0
Body weight	1.9	7.9	18.0	-4.2	-4.2	1.7	3.6	1.2	2.3	-4.2	0.3	1.3	0.9
Weight adjusted by age	1.3	1.5	2.2	-1.4	-1.5	1.4	1.3	1.5	1.4	-1.2	-1.0	-0.4	-0.8
Bone surface	1.9	3.4	6.8	-1.8	-1.8	2.3	1.8	2.3	2.6	-1.3	-1.5	-1.1	-1.2
Bone volume	1.4	2.4	5.5	-1.1	-1.1	2.0	1.1	2.1	2.3	-0.6	-1.5	-1.4	-1.3
Breakpoint value in progressive ratio session	1.5	1.6	3.0	-1.5	-1.5	1.7	1.6	1.3	0.4	-1.3	-1.2	0.0	-1.0
Number of licking bursts	0.0	0.0	0.0	-0.1	-0.1	0.0	-0.2	0.1	0.1	-0.0	-0.1	-0.1	-0.1
Context. condit. distance diff. score	0.5	0.6	1.2	1.0	0.9	-1.1	-0.5	-0.9	0.1	0.4	1.1	0.3	1.0
Locomotion velocity, session 1	0.9	0.9	2.3	0.3	0.2	-1.3	0.2	-1.2	-0.4	-0.2	1.5	1.1	1.5
Locomotion distance, session 1	0.6	0.7	1.6	-0.6	-0.5	-0.7	0.9	-0.6	0.4	-1.0	1.2	0.9	1.3
Locomotion velocity, session 2	1.4	1.7	4.0	-1.8	-1.8	1.0	2.0	0.7	0.9	-2.0	-0.1	0.4	0.2
Locomotion distance, session 2	0.4	0.5	0.9	-0.4	-0.3	-0.6	0.6	-0.7	-0.4	-1.0	0.9	0.9	0.9
Locomotion velocity, session 3	0.3	0.4	1.3	-0.5	-0.5	-0.2	0.5	-0.1	1.1	-0.7	0.7	0.1	0.8
Locomotion distance, session 3	0.2	0.3	0.7	-0.3	-0.3	-0.5	0.1	-0.6	-0.2	-0.2	0.8	0.7	0.8
Stereotopy head waving bouts, day 3	0.2	0.3	1.2	0.6	0.5	-0.2	-0.1	0.0	1.1	-0.4	0.3	-0.7	0.2
Stereotopy head waving duration, day 3	0.2	0.2	0.4	0.7	0.6	-0.7	-0.2	-0.5	0.3	-0.4	0.6	-0.2	0.5
Locomotion velocity, session 7	0.1	0.1	0.4	0.2	0.3	0.2	-0.0	0.2	0.6	-0.1	-0.1	-0.5	-0.2
Locomotion distance, session 7	0.4	0.5	1.2	0.5	0.5	-0.9	-0.3	-0.9	-0.0	-0.1	1.1	0.5	1.1
Stereotopy head waving bouts, day 7	0.7	0.8	1.4	-0.2	-0.3	1.0	0.5	1.2	1.1	-0.4	-1.1	-1.1	-1.1
Stereotopy head waving duration, day 7	1.3	1.5	2.7	-1.6	-1.6	1.2	1.6	1.2	1.2	-1.5	-0.8	-0.3	-0.5
Locomotion velocity, session 8	1.0	1.2	2.3	0.5	0.4	-1.5	0.1	-1.5	-1.2	-0.3	1.4	1.3	1.4
Locomotion distance, session 8	0.2	0.3	0.6	0.8	0.8	-0.6	-0.4	-0.4	0.5	0.1	0.6	-0.2	0.5
Degree of sensitization distance	0.2	0.2	1.2	0.4	0.4	-0.0	-0.2	0.1	1.1	-0.1	0.2	-0.5	0.2
Degree of sensitization stereotypy	1.3	1.4	2.3	-1.0	-1.1	1.5	1.2	1.5	1.2	-0.8	-1.3	-0.9	-1.2
Conditioned locomotion	0.3	0.3	1.1	-0.7	-0.8	0.3	0.8	0.1	0.1	-1.0	0.1	0.4	0.2
Cocaine response after cond. corrected	1.5	1.7	3.2	1.2	1.2	-1.7	-0.7	-1.8	-1.0	0.4	1.7	0.9	1.6
Cocaine response after cond. not corrected	0.9	1.0	1.8	1.0	1.0	-1.3	-0.6	-1.3	-0.5	0.7	1.3	0.6	1.2
Cocaine response before conditioning	0.9	1.1	2.2	-0.9	-0.8	1.3	0.7	1.5	1.1	0.3	-1.3	-0.8	-1.2
Saline control response	1.3	1.7	3.9	-1.9	-2.0	0.3	1.7	-0.1	0.2	-1.7	0.7	1.4	1.0
Bone: connectivity density	0.9	1.5	3.3	-1.6	-1.6	0.9	1.7	1.1	1.8	-1.4	-0.2	-0.1	0.0
Bone: cortical apparent density	0.2	0.3	1.0	-0.7	-0.7	-0.0	1.0	0.0	-0.4	-0.7	-0.0	0.6	0.1
Bone: cortical area	1.0	1.5	2.7	-1.3	-1.3	1.6	1.1	1.5	1.5	-0.8	-1.1	-0.7	-0.9
Bone: cortical porosity	0.1	0.1	0.4	0.3	0.3	0.1	-0.1	-0.0	-0.7	-0.0	-0.4	-0.1	-0.4
Bone: cortical porosity	0.1	0.1	0.7	0.0	-0.0	-0.0	0.2	-0.2	-0.8	-0.4	-0.1	0.4	-0.1
Bone: cortical thickness	1.6	2.6	5.9	-2.4	-2.4	0.3	2.3	0.0	-0.3	-2.2	0.4	1.8	0.8
Bone: cortical thickness	0.7	0.9	2.2	-0.7	-0.7	-0.8	0.8	-0.8	-0.9	-0.7	1.0	1.5	1.1
Bone: cortical tissue density	0.3	0.4	1.2	-0.8	-0.8	0.0	1.1	0.0	-0.5	-0.8	-0.0	0.7	0.1
Condit. Reinf. active minus inactive responses	0.5	0.6	1.4	-1.1	-1.1	0.7	1.2	0.7	0.7	-0.9	-0.3	0.2	-0.1
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.5	-0.6	-0.6	0.0	0.7	-0.0	-0.2	-0.5	0.1	0.6	0.3
Condit. Reinf. active responses	1.1	1.4	2.6	-1.1	-1.1	1.4	1.2	1.5	1.6	-0.8	-1.1	-0.8	-0.9
Condit. Reinf. inactive responses	1.1	1.3	2.7	-0.1	-0.1	1.3	-0.0	1.5	1.7	0.3	-1.3	-1.6	-1.3
Incentive salience index mean	0.8	0.9	1.8	-1.3	-1.3	0.8	1.3	0.9	1.3	-1.0	-0.2	0.0	-0.0
Condit. Reinf. lever presses	0.5	0.7	2.2	-1.1	-1.1	0.7	1.0	0.8	1.5	-0.7	-0.1	-0.2	0.0
Condit. Reinf. active minus inactive responses	0.7	0.9	1.9	0.5	0.5	0.9	-0.6	1.0	0.4	1.0	-1.3	-1.3	-1.4
Condit. Reinf. active-inactive response ratio	2.4	2.6	6.1	0.8	0.8	1.6	-0.7	1.8	1.4	0.9	-2.1	-2.5	-2.2
Condit. Reinf. active responses	0.1	0.1	0.2	-0.2	-0.2	0.5	-0.0	0.5	0.2	0.4	-0.5	-0.3	-0.5
Condit. Reinf. inactive responses	0.9	1.1	2.9	-0.5	-0.4	-1.1	0.2	-1.2	-0.9	0.0	1.4	1.7	1.5
Condit. Reinf. lever presses	0.9	1.2	2.3	-1.3	-1.3	1.5	1.0	1.4	1.2	-0.5	-1.0	-0.5	-0.8
Condit. Reinf. lever reinforcers received	0.2	0.3	0.7	-0.5	-0.5	0.8	0.3	0.7	0.3	0.1	-0.7	-0.3	-0.6
Conditioned reinforcement - actives	1.9	1.9	3.0	1.6	1.5	0.5	-1.3	0.8	0.0	1.7	-1.5	-1.7	-1.7
Conditioned reinforcement - inactives	1.3	1.5	3.6	0.9	0.9	0.7	-0.9	1.1	1.0	1.2	-1.4	-1.9	-1.5
Conditioned locomotion	1.1	1.3	3.5	1.9	1.5	-0.1	-1.4	0.2	0.5	1.5	-0.4	-1.5	-0.6
Patch foraging indifference point 0 sec	0.3	0.4	0.9	-0.9	-0.9	0.4	0.9	0.2	0.4	-0.9	0.1	0.4	0.2
Patch foraging indifference point AUC	3.0	3.5	6.8	-1.8	-1.8	2.6	1.9	2.3	1.4	-1.3	-2.1	-1.0	-1.8
Delay disc. indifference point, 0s delay	0.7	0.7	1.9	0.3	0.6	-1.3	-0.5	-1.1	0.0	-0.1	1.4	0.5	1.3
Delay disc. indifference point, 16s delay	0.2	0.2	0.9	-0.4	-0.3	0.4	0.3	0.6	1.0	-0.2	-0.4	-0.6	-0.3
Delay disc. indifference point, 2s delay	0.1	0.1	0.4	0.4	0.5	-0.3	-0.4	0.0	0.6	0.3	0.1	-0.5	0.0
Delay disc. indifference point, 24s delay	0.5	0.5	1.3	-0.2	-0.3	-0.5	0.2	-0.8	-0.3	-0.6	1.1	1.0	1.1
Delay disc. indifference point, 4s delay	1.0	1.0	2.5	-0.4	-0.4	-1.2	0.5	-1.0	-0.1	-1.1	1.5	1.2	1.6
Delay disc. indifference point, 8s delay	0.9	0.9	1.8	0.7	0.6	-1.2	-0.7	-1.3	-0.8	0.0	1.3	0.8	1.2
Indifference point function ln k	5.3	7.4	14.0	2.6	2.5	-3.7	-2.4	-3.4	-1.7	1.9	3.4	1.7	3.1
Indifference point function log k	5.3	7.4	14.0	2.6	2.5	-3.7	-2.4	-3.4	-1.7	1.9	3.4	1.7	3.1
Patch foraging total patch changes 0 sec	0.3	0.5	1.0	-0.9	-0.9	-0.1	0.9	-0.3	-0.1	-1.0	0.6	1.0	0.7
Patch foraging total patch changes 12 sec	4.0	5.1	10.9	-2.9	-3.0	2.5	3.3	1.9	1.2	-3.0	-1.3	0.2	-0.9
Patch foraging total patch changes 18 sec	0.5	0.7	1.5	-0.9	-0.7	1.2	1.0	0.9	0.2	-0.8	-0.9	-0.2	-0.8
Patch foraging total patch changes 24 sec	3.9	4.7	9.6	-3.1	-3.1	1.9	3.1	1.4	1.6	-3.1	-0.5	0.7	-0.0
Patch foraging total patch changes 6 sec	0.6	0.8	2.1	-1.3	-1.3	0.6	1.4	0.4	0.6	-1.3	0.1	0.5	0.3
Patch foraging time to switch 0 sec	0.8	1.2	2.8	-0.7	-0.6	1.3	0.9	1.4	1.7	-0.7	-1.1	-1.2	-1.0
Patch foraging water rate 0 sec	0.6	1.0	1.6	0.9	0.8	-1.1	-1.0	-1.2	-1.2	1.0	0.9	0.8	0.8
Patch foraging water rate 12 sec	3.0	4.5	7.6	1.7	1.5	-2.8	-2.0	-2.8	-2.1	1.5	2.5	1.8	2.3
Patch foraging water rate 18 sec	2.9	4.0	7.9	1.1	1.0	-2.8	-1.3	-2.6	-1.3	0.7	2.8	1.9	2.7
Patch foraging water rate 24 sec	1.7	2.4	4.3	1.5	1.5	-2.1	-1.6	-1.9	-1.5	1.2	1.6	1.0	1.4
Patch foraging water rate 6 sec	2.3	3.4	6.3	1.3	1.3	-2.5	-1.6	-2.4	-1.8	0.9	2.2	1.6	2.0
Seeking ratio, delayed vs. immediate footshock	0.0	0.0	0.1	-0.2	-0.0	-0.2	0.0	-0.3	0.0	-0.1	0.4	0.2	0.4
Distance traveled before self-admin	2.1	2.2	3.8	-1.8	-1.7	2.0	1.7	1.7	1.3	-1.1	-1.3	-0.5	-1.1
Distance traveled after self-admin	0.4	0.5	0.9	-0.8	-0.7	0.9	0.4	0.9	0.3	-0.1	-0.9	-0.3	-0.8
Extensor digitorum longus weight	3.4	13.3	30.6	-5.5	-5.5	2.6	5.1	2.0	2.7	-5.1	-0.2	1.5	0.6
Bone: elastic displacement	1.2	1.4	3.1	0.8	0.8	-1.7	-0.8	-1.5	-1.8	0.6	1.1	1.1	1.0
Bone: elastic work	1.0	1.3	2.8	-0.9	-0.9	-0.9	1.0	-1.0	-0.8	-1.1	1.3	1.7	1.4
Bone: endosteal estimation	1.1	2.4	5.8	1.6	1.6	0.7	-1.7	1.0	2.1	1.7	-0.8	-2.4	-1.1
Bone: endosteal perimeter	2.3	4.9	11.9	1.8	1.8	1.6	-2.0	1.9	2.6	2.2	-1.9	-3.4	-2.2
Epididymis fat weight	0.2	0.4	1.3	0.5	0.6	-0.2	-1.2	0.0	0.9	0.8	0.2	-0.9	0.0
Delta time in closed arm before/after self-admin	2.9	2.8	6.3	-1.0	-1.0	-1.4	1.1	-1.7	-0.4	-1.8	2.3	2.2	2.5
Delta time in open arm before/after self-admin	2.4	2.4	4.2	-1.3	-1.3	2.0	1.5	2.0	1.3	-0.9	-1.9	-1.1	-1.7
Diff in mean of infusions in LGA sessions	0.8	0.9	2.2	-1.3	-1.4	0.6	1.5	0.5	-0.2	-1.5	-0.4	0.8	-0.1
Delay discount exponential model param	0.2	0.2	0.5	0.0	0.0	0.5	-0.1	0.4	-0.2	0.4	-0.7	-0.3	-0.7
Extinction: sum of active levers before priming	2.2	2.2	4.5	-2.1	-2.1	1.5	2.0	1.4	1.1	-1.7	-0.9	0.2	-0.5
Active lever presses in extinction session 6	2.4	2.3	3.7	-1.6	-1.8	1.9	1.9	1.8	1.0	-1.2	-1.6	-0.4	-1.3
Bone: final force	1.4	2.2	3.8	-1.9	-1.9	1.5	1.8	1.5	1.9	-1.6	-0.7	-0.2	-0.4
Bone: final moment	1.3	2.1	3.7	-1.9	-1.9	1.5	1.8	1.5	1.9	-1.5	-0.7	-0.3	-0.4
Food consumed during 24 hour testing period	0.2	0.2	0.5	0.1	0.1	0.5	-0.5	0.5	0.2	0.7	-0.6	-0.5	-0.6
Glucose	1.3	2.0	5.1	2.0	2.0	-0.6	-2.3	-0.3	0.2	2.0	-0.1	-1.4	-0.4
Heart weight	1.0	1.4	2.6	1.2	1.2	-1.6	-1.4	-1.4	-0.4	0.6	1.4	0.4	1.3
Delay discount hyperbolic model param	0.2	0.2	0.5	0.1	0.0	0.5	-0.1	0.4	-0.3	0.4	-0.7	-0.3	-0.7
Intermittent access intake day 1-15 change	1.6	1.6	3.5	1.0	1.2	0.9	-1.0	0.9	-0.5	1.5	-1.7	-1.4	-1.9
Intermittent access intake escalation	1.2	1.1	2.7	0.8	0.9	0.9	-0.7	0.8	-0.4	1.2	-1.5	-1.2	-1.6
Intermittent access intake escalation 2	1.2	1.2	3.1	0.0	0.1	1.6	0.1	1.3	0.2	0.4	-1.7	-1.1	-1.7
Intermitt. access day 1 inactive lever presses	0.9	1.0	2.1	1.4	1.5	-0.3	-1.3	0.0	0.0	1.4	-0.4	-1.2	-0.6
Intermitt. access day 15 inactive lever presses	1.2	1.3	3.1	-0.5	-0.3	1.3	0.3	1.6	1.7	0.1	-1.3	-1.6	-1.3
Intermitt. access escalation Index	1.1	1.0	2.6	0.4	0.5	-1.6	-0.6	-1.3	-0.5	0.2	1.5	0.8	1.4
Intermittent access day 1 total infusions	0.7	0.8	3.0	1.0	0.9	-0.1	-0.7	0.3	1.7	0.6	0.1	-1.5	-0.1
Intermittent access day 15 total infusions	2.3	2.6	5.5	2.0	1.9	0.4	-1.7	0.8	0.8	2.0	-1.3	-2.4	-1.5
Intermittent access terminal intake (last 3 days)	2.1	2.3	6.0	0.8	0.7	1.5	-0.5	1.7	1.9	0.9	-1.7	-2.4	-1.8
Intermittent access total infusions	1.3	1.4	4.2	1.0	1.0	0.7	-0.7	1.1	1.6	1.0	-1.0	-2.0	-1.2
Intermittent access day 1 locomotion	0.5	0.5	2.7	0.5	0.4	-0.6	-0.1	-0.1	1.7	-0.1	0.8	-0.7	0.7
Intermittent access day 15 total locomotion	0.8	0.9	2.5	0.6	0.3	0.9	-0.1	1.1	1.5	0.3	-0.9	-1.6	-1.0
Intermittent access total locomotion	1.8	2.1	7.8	0.4	0.2	1.3	0.1	1.7	2.8	0.2	-1.2	-2.3	-1.2
Intermittent access standard deviation	1.0	1.1	1.8	1.4	1.2	0.3	-1.0	0.4	-0.5	1.3	-1.1	-1.1	-1.3
Left kidney weight	0.2	0.5	1.2	-0.4	-0.3	0.9	-0.0	0.9	1.1	-0.4	-0.8	-0.9	-0.7
Right kidney weight	0.6	1.6	2.9	-0.8	-0.5	1.5	0.4	1.7	1.7	-0.6	-1.5	-1.5	-1.4
Cocaine induced anxiety	0.6	0.7	2.2	-0.5	-0.5	1.5	0.6	1.1	0.7	-0.3	-1.0	-0.6	-0.9
Post-drug Anxiety	1.3	1.4	3.5	-0.9	-0.9	1.9	0.9	1.6	0.9	-0.6	-1.5	-0.8	-1.4
Baseline Anxiety	0.5	0.6	1.2	-1.1	-1.1	0.0	1.0	0.0	0.0	-1.1	0.3	0.8	0.4
Tail length	0.6	1.9	3.8	-1.8	-1.8	-0.4	1.5	-0.6	-1.0	-2.0	0.8	1.9	1.0
Length with tail	1.1	4.2	10.5	-3.2	-3.2	1.1	2.7	0.8	0.7	-3.1	0.0	1.4	0.5
Length without tail	1.1	2.4	5.5	-2.3	-2.3	1.5	1.9	1.2	1.3	-2.0	-0.4	0.3	-0.1
Times rat made contact with spout	0.6	0.7	1.7	-0.3	-0.3	-0.8	0.2	-1.0	-1.0	-0.5	0.9	1.3	1.0
Lifetime Intake	0.6	0.7	1.9	1.0	1.0	-0.1	-0.8	0.3	1.1	0.9	-0.3	-1.4	-0.4
Liver weight, left	0.3	0.4	0.7	0.7	0.7	-0.5	-0.8	-0.8	-0.8	0.8	0.6	0.3	0.5
Liver weight, right	0.1	0.2	0.6	-0.1	-0.0	-0.3	-0.2	-0.4	0.4	0.1	0.8	0.3	0.8
Locomotor activity	2.2	3.5	6.4	1.3	1.1	-2.4	-1.4	-2.5	-2.1	0.6	2.2	1.8	2.1
Locomotor testing distance	3.1	5.1	9.5	1.4	1.3	-3.1	-1.4	-3.1	-2.3	0.6	2.9	2.2	2.8
Locomotor testing rearing	1.7	2.7	5.1	1.3	1.3	-2.3	-1.5	-2.1	-1.5	1.1	1.9	1.3	1.7
Locomotion in novel chamber	1.9	2.3	5.0	1.7	1.5	0.3	-1.6	1.1	0.9	1.9	-1.4	-2.2	-1.7
Locomotion in novel chamber post-restriction	1.2	1.5	4.1	2.0	1.9	-0.5	-1.7	-0.3	-0.6	1.4	-0.4	-0.9	-0.7
Fecal boli incidents, locomotor time 1	1.5	1.7	3.6	0.4	0.3	1.6	-0.4	1.5	0.9	0.9	-1.8	-1.8	-1.9
Change in fecal boli incidents, locomotor task	2.3	2.1	4.7	1.0	0.9	-2.2	-0.9	-2.0	-1.1	0.2	2.0	1.2	1.9
Time >=10cm from walls, locomotor time 1	2.4	2.4	5.8	1.6	1.3	0.8	-1.4	1.2	1.2	1.8	-1.5	-2.4	-1.8
Bouts of movement, locomotor time 1	0.3	0.4	1.1	-0.3	-0.5	0.5	0.5	0.4	-1.1	-0.3	-0.9	0.2	-0.9
Total resting periods, locomotor time 1	0.4	0.4	1.2	-0.4	-0.5	0.7	0.6	0.7	-0.6	-0.2	-1.1	-0.1	-1.0
Rest time, locomotor task time 1	0.7	0.8	1.7	0.9	1.3	-0.7	-1.3	-0.5	-1.1	1.3	-0.0	-0.2	-0.3
Distance moved, locomotor task time 1	0.1	0.2	0.5	-0.3	-0.6	0.3	0.6	0.2	0.7	-0.4	0.1	0.0	0.2
Vertical activity count, locomotor time 1	0.4	0.4	1.1	1.1	0.8	-0.4	-0.8	-0.5	-0.2	0.8	0.3	-0.2	0.2
Time >=10cm from walls, locomotor time 2	0.8	0.9	2.2	0.3	0.1	1.1	-0.2	1.1	0.3	0.7	-1.4	-1.2	-1.5
Bouts of movement, locomotor time 2	0.7	0.7	1.9	-1.4	-1.3	0.6	1.2	0.4	0.1	-1.1	-0.2	0.6	-0.0
Total resting periods, locomotor time 2	0.3	0.4	1.0	-1.0	-0.9	0.6	0.8	0.4	0.1	-0.7	-0.2	0.3	-0.1
Rest time, locomotor task time 2	1.6	1.9	4.5	1.9	2.1	-1.0	-2.1	-0.9	-0.9	1.8	0.3	-0.6	-0.0
Distance moved, locomotor task time 2	0.2	0.3	0.7	-0.5	-0.9	0.4	0.8	0.3	-0.2	-0.5	-0.3	0.4	-0.2
Vertical activity count, locomotor time 2	0.8	0.9	2.5	0.4	0.1	-1.0	-0.1	-1.2	-1.6	-0.1	1.0	1.4	1.0
Light reinforcement 1	0.1	0.1	0.4	0.1	0.3	-0.3	-0.4	-0.3	-0.6	0.6	0.1	0.3	0.1
Light reinforcement 2	2.1	2.9	5.8	0.1	0.3	1.9	-0.3	2.1	1.7	0.9	-2.3	-2.4	-2.4
Bone: marrow area	1.1	2.5	5.7	1.7	1.7	0.6	-1.8	0.9	2.0	1.8	-0.8	-2.4	-1.0
Bone: maximum diameter	1.1	2.0	4.1	-0.5	-0.5	2.0	0.4	1.9	2.0	-0.2	-1.6	-1.7	-1.6
Bone: maximum force	2.5	4.3	10.1	-2.3	-2.2	2.4	2.1	2.4	3.2	-1.7	-1.3	-1.1	-0.9
Bone: maximum moment	2.2	3.9	8.9	-2.2	-2.2	2.3	2.0	2.2	3.0	-1.7	-1.2	-1.0	-0.9
Mean time between licks in bursts	1.8	2.5	5.5	-0.8	-0.9	-1.4	0.6	-1.7	-0.9	-1.2	2.2	2.3	2.4
Mean num. licks in bursts	0.3	0.3	0.8	0.2	0.2	-0.7	-0.1	-0.8	-0.9	0.1	0.6	0.8	0.6
Cd content in liver	0.7	0.8	1.9	1.4	1.4	0.1	-1.1	0.1	0.0	1.2	-0.5	-0.9	-0.7
Co content in liver	3.4	4.0	7.7	1.7	1.6	-2.6	-1.5	-2.5	-2.8	1.5	1.9	1.7	1.7
Cu content in liver	0.6	0.7	1.6	-0.4	-0.4	-0.7	0.4	-0.9	-0.8	-0.8	1.0	1.3	1.1
Fe content in liver	0.1	0.2	0.3	0.2	0.1	0.4	0.1	0.5	0.5	-0.1	-0.5	-0.6	-0.5
K content in liver	1.1	1.1	2.9	-1.2	-1.2	1.1	0.9	1.2	1.7	-0.8	-0.6	-0.6	-0.5
Mg content in liver	0.5	0.5	2.6	-0.6	-0.7	0.6	0.5	0.8	1.6	-0.5	-0.2	-0.5	-0.1
Mn content in liver	1.6	1.8	3.3	-1.8	-1.8	1.5	1.5	1.4	1.3	-1.4	-0.9	-0.2	-0.7
Na content in liver	1.1	1.1	2.2	-1.0	-0.9	1.5	0.9	1.4	1.3	-0.5	-1.0	-0.7	-0.9
Rb content in liver	1.1	1.4	2.3	1.4	1.4	-1.5	-1.5	-1.3	-0.6	1.3	1.1	0.2	0.9
Se content in liver	1.8	2.3	4.3	-0.6	-0.6	2.1	0.4	2.1	1.7	-0.4	-1.9	-1.7	-1.9
Sr content in liver	3.4	3.1	6.3	-2.5	-2.4	1.7	2.4	1.3	0.8	-2.5	-0.9	0.3	-0.6
Zn content in liver	2.8	3.1	5.8	-2.2	-2.2	1.9	2.4	1.7	1.6	-2.1	-1.1	-0.2	-0.7
Bone: minimum diameter	1.1	2.1	5.3	0.8	0.9	1.2	-1.2	1.4	2.3	1.3	-1.1	-2.2	-1.2
Time in familiar zone, hab. session 1	0.1	0.1	0.3	-0.2	-0.3	0.1	0.2	0.1	0.6	0.1	0.2	0.1	0.3
Time in novel zone, hab. session 1	1.2	1.2	2.1	1.2	1.2	-1.4	-1.2	-1.2	-1.2	1.1	0.9	0.5	0.7
Total zone transitions, hab. session 1	0.1	0.2	0.6	-0.5	-0.5	0.2	0.6	0.0	0.0	-0.8	0.1	0.3	0.2
Total locomotion distance, hab. session 1	0.2	0.3	1.0	0.4	0.4	0.4	-0.1	0.6	1.0	0.0	-0.5	-0.9	-0.5
Locomotion velocity, hab. session 1	0.3	0.4	0.9	-0.2	-0.2	0.7	0.5	0.8	0.9	-0.6	-0.6	-0.7	-0.5
Time in familiar zone, hab. session 2	1.1	1.1	2.2	0.4	0.3	-1.4	-0.8	-1.3	-1.5	1.0	1.1	1.2	1.0
Time in novel zone, hab. session 2	0.5	0.5	1.4	-0.6	-0.6	0.7	0.9	0.7	1.2	-1.0	-0.3	-0.4	-0.2
Total zone transitions, hab. session 2	0.8	1.0	2.0	-1.4	-1.3	-0.0	1.4	-0.2	0.6	-1.3	0.8	1.0	1.0
Total locomotion distance, hab. session 2	0.1	0.2	0.5	-0.3	-0.2	-0.1	0.4	-0.0	0.7	-0.4	0.5	0.1	0.5
Locomotion velocity, hab. session 2	0.1	0.1	0.9	-0.1	-0.1	0.1	0.3	0.2	1.0	-0.3	0.1	-0.3	0.2
Novel to familiar place preference ratio	2.0	2.1	3.3	-1.7	-1.6	1.8	1.5	1.5	1.3	-1.8	-1.1	-0.5	-0.9
Novelty place preference	1.5	1.5	2.7	-1.4	-1.3	1.6	1.1	1.3	1.1	-1.4	-1.1	-0.6	-0.9
Time in novel zone, NPP test	1.3	1.3	2.2	-1.4	-1.3	1.5	1.2	1.2	1.0	-1.5	-0.9	-0.5	-0.7
Total zone transitions, NPP test	0.6	0.9	2.4	-1.1	-1.1	0.1	1.5	-0.2	0.2	-1.5	0.6	0.9	0.8
Total locomotion distance, NPP test	0.2	0.2	0.5	-0.1	0.0	-0.4	0.4	-0.5	0.0	-0.6	0.7	0.5	0.7
Locomotion velocity, NPP test	0.1	0.1	0.3	0.1	0.1	-0.3	0.3	-0.4	-0.1	-0.5	0.5	0.3	0.5
Intraocular pressure	0.1	0.1	0.3	0.2	0.2	0.1	-0.4	0.1	-0.6	0.4	-0.5	-0.2	-0.6
Delta distance traveled before/after self-admin	0.8	0.9	1.9	0.8	0.8	-1.4	-1.0	-1.1	-1.0	0.8	0.9	0.7	0.8
Delta ambulatory time before/after self-admin	1.4	1.5	2.5	1.1	1.1	-1.6	-1.3	-1.5	-1.4	0.9	1.2	0.9	1.0
Parametrial fat weight	0.9	1.8	3.5	1.8	1.6	0.0	-1.7	0.5	1.1	1.7	-0.6	-1.9	-0.9
Pavlov. Cond. lever latency	1.0	1.3	3.2	1.2	1.3	-1.2	-1.3	-1.2	-1.8	1.0	0.6	0.5	0.4
Pavlov. Cond. magazine entry latency	1.6	2.0	4.0	-1.2	-1.3	1.8	1.2	1.9	2.0	-0.7	-1.4	-1.1	-1.2
Pavlov. Cond. change in total contacts	1.9	2.1	4.0	-0.4	-0.6	1.9	0.7	2.0	1.8	-0.1	-1.8	-1.6	-1.7
Pavlov. Cond. index score	0.9	1.1	2.1	-0.9	-1.0	1.4	0.9	1.4	1.3	-0.4	-1.1	-0.8	-1.0
Pavlov. Cond. latency score	0.6	0.7	1.7	-0.8	-0.9	1.0	0.8	1.1	1.3	-0.4	-0.7	-0.5	-0.6
Pavlov. Cond. lever contacts	0.3	0.3	1.2	-0.5	-0.6	0.6	0.5	0.7	1.1	-0.2	-0.4	-0.4	-0.3
Pavlov. Cond. magazine entry number	1.2	1.5	2.9	0.9	1.0	-1.7	-1.1	-1.7	-1.2	0.5	1.5	0.9	1.4
Pavlov. Cond. intertrial magazine entries	0.4	0.4	1.2	-0.2	-0.1	0.8	0.3	0.8	0.0	-0.2	-1.1	-0.6	-1.1
Pavlov. Cond. lever-magazine prob. diff.	1.2	1.5	2.7	-1.0	-1.1	1.6	1.1	1.6	1.4	-0.6	-1.3	-0.9	-1.2
Pavlov. Cond. response bias	1.2	1.5	2.7	-1.0	-1.0	1.6	1.0	1.7	1.5	-0.5	-1.3	-0.9	-1.2
Pavlov. Cond. lever latency	0.4	0.6	1.4	0.9	0.8	-1.0	-0.7	-0.9	-1.2	0.2	0.5	0.4	0.4
Pavlov. Cond. magazine entry latency	2.5	2.8	6.5	-2.4	-2.4	1.6	2.5	1.4	1.2	-1.8	-0.8	0.3	-0.4
Pavlov. Cond. change in total contacts	2.1	2.9	6.1	-1.6	-1.6	2.5	1.5	2.2	1.9	-0.4	-1.8	-1.1	-1.6
Pavlov. Cond. index score	2.3	2.9	4.8	-2.1	-2.0	2.2	2.0	2.0	1.8	-1.1	-1.4	-0.6	-1.1
Pavlov. Cond. latency score	2.2	2.7	4.5	-1.9	-1.9	2.1	1.9	2.0	1.9	-1.1	-1.4	-0.7	-1.1
Pavlov. Cond. lever contacts	0.3	0.5	1.0	-0.8	-0.8	1.0	0.7	0.8	0.6	-0.1	-0.7	-0.2	-0.5
Pavlov. Cond. magazine entry number	4.5	5.5	10.6	3.2	3.2	-2.6	-3.3	-2.2	-1.9	2.4	1.4	-0.0	0.9
Pavlov. Cond. intertrial magazine entries	0.8	1.1	2.4	1.5	1.6	-0.5	-1.5	-0.3	-0.8	1.4	-0.3	-0.7	-0.5
Pavlov. Cond. lever-magazine prob. diff.	2.3	3.0	4.8	-2.2	-2.1	2.2	2.1	1.9	1.8	-1.2	-1.3	-0.4	-1.0
Pavlov. Cond. response bias	1.1	1.5	2.9	-1.7	-1.6	1.6	1.5	1.3	1.1	-0.9	-0.9	-0.1	-0.6
Time in closed arm before self-admin	0.8	0.9	1.8	-0.1	0.1	1.1	-0.1	1.2	0.8	0.5	-1.3	-1.2	-1.4
Time in closed arm after self-admin	0.7	0.7	1.5	0.7	0.8	-1.2	-0.9	-1.1	-0.6	0.5	1.0	0.5	0.9
Time in open arm before self-admin	4.0	4.3	8.4	1.1	1.0	-2.8	-1.1	-2.9	-2.1	0.3	2.8	2.1	2.6
Time in open arm after self-admin	0.2	0.2	0.8	0.0	-0.1	-0.3	0.3	-0.5	-0.9	-0.3	0.3	0.7	0.3
Bone: periosteal estimation	1.1	2.2	6.3	0.0	0.1	1.8	-0.2	1.9	2.5	0.5	-1.5	-2.1	-1.5
Bone: periosteal perimeter	1.2	1.9	3.8	-0.1	-0.0	1.8	-0.1	1.8	2.0	0.4	-1.6	-1.9	-1.6
Bone: post-yield work	2.9	4.0	10.6	0.4	0.5	2.2	-0.4	2.4	3.3	0.9	-2.0	-3.0	-2.1
Progressive ratio test 1 active lever presses	1.0	1.1	3.0	1.7	1.5	-0.6	-1.3	-0.1	-0.1	1.4	-0.3	-1.1	-0.6
Progressive ratio test 1 breakpoint	1.2	1.2	3.3	1.8	1.6	-0.6	-1.4	-0.1	-0.2	1.5	-0.4	-1.1	-0.6
Progressive ratio test 1 inactive lever presses	0.2	0.2	0.6	-0.1	-0.1	-0.8	0.3	-0.4	0.3	-0.5	0.7	0.3	0.7
Progressive ratio test 2 active lever presses	1.4	1.5	3.5	1.5	1.3	0.3	-1.1	0.8	0.8	1.3	-1.1	-1.9	-1.3
Progressive ratio test 2 breakpoint	1.7	1.9	3.6	1.9	1.8	0.1	-1.5	0.6	0.3	1.7	-1.1	-1.9	-1.4
Progressive ratio test 2 inactive lever presses	1.1	1.2	3.7	0.8	0.8	0.7	-0.5	1.1	1.4	0.7	-1.2	-1.9	-1.3
Incentive Sensitization - Responses	0.9	0.9	1.9	-0.3	-0.3	1.1	0.4	1.3	1.4	-0.2	-1.1	-1.2	-1.0
Incentive Sensitization - Breakpoint	0.9	0.9	2.0	-0.2	-0.2	1.1	0.3	1.3	1.4	-0.1	-1.2	-1.3	-1.1
Sum of active levers in priming session hrs 5-6	3.4	3.3	7.3	-1.2	-1.1	2.7	1.2	2.4	0.8	-0.5	-2.6	-1.3	-2.5
Progressive ratio	0.4	0.4	0.9	-0.2	-0.3	0.9	-0.0	0.9	0.9	0.3	-0.7	-0.8	-0.7
Food seeking constrained by brief footshock	0.5	0.6	1.2	0.3	0.3	-1.1	-0.4	-1.1	-0.8	0.2	1.0	0.8	1.0
Seeking ratio, punishment vs. effort	1.3	1.6	3.1	0.4	0.5	-1.8	-0.2	-1.7	-1.4	-0.4	1.7	1.5	1.6
Retroperitoneal fat weight	1.1	3.7	10.1	2.8	2.8	-1.4	-3.2	-1.1	-0.1	2.4	0.7	-1.3	0.3
Reaction time number correct	0.5	0.7	1.6	-1.1	-1.1	-0.2	0.5	-0.5	-0.4	-0.6	0.8	1.3	0.9
Reaction time mean minus median	1.9	2.6	6.0	-0.7	-0.6	2.3	0.7	2.1	0.7	-0.3	-2.4	-1.6	-2.4
Reaction time mean minus median AUC	0.6	0.8	2.2	-0.4	-0.3	1.2	0.4	1.0	-0.3	-0.1	-1.5	-0.6	-1.4
Reaction time num false alarms	2.0	2.7	5.1	0.7	0.7	-2.1	-0.5	-2.3	-1.9	-0.0	2.1	1.9	2.0
Reaction time num false alarms AUC	2.0	2.7	5.3	0.2	0.2	-1.8	0.0	-2.2	-2.0	-0.7	2.1	2.3	2.1
Reaction time trials correct on left	0.5	0.7	1.6	-1.1	-1.1	-0.2	0.5	-0.5	-0.4	-0.6	0.8	1.3	0.9
Reaction time trials on left	0.5	0.7	1.7	-1.1	-1.1	-0.2	0.6	-0.5	-0.4	-0.6	0.8	1.3	0.9
Reaction time mean	0.7	1.0	2.5	0.3	0.3	1.1	0.1	1.2	0.3	0.5	-1.6	-1.2	-1.6
Reaction time mean AUC	0.7	1.0	2.5	0.3	0.4	1.0	-0.0	1.2	0.3	0.8	-1.5	-1.3	-1.6
Median of all reaction times	0.4	0.5	1.1	0.1	0.1	0.8	0.4	0.9	0.5	0.3	-1.1	-0.9	-1.0
Reaction time omissions	0.1	0.2	0.9	-0.0	-0.0	0.2	0.4	-0.1	-1.0	-0.3	-0.3	0.4	-0.2
Reaction time false alarm rate	1.0	1.4	2.8	0.8	0.8	-1.6	-0.4	-1.7	-1.4	-0.1	1.5	1.2	1.4
Reaction time premature initiation rate	2.4	3.3	6.1	-2.5	-2.4	-0.3	2.3	-0.4	0.7	-2.4	1.5	2.0	1.8
Reaction time premature initiations	3.2	4.5	8.7	-2.9	-2.9	-0.3	2.5	-0.6	0.1	-2.7	1.7	2.6	2.1
Std. dev. reaction times	0.8	1.1	3.3	0.3	0.3	1.2	-0.1	1.1	-0.3	0.5	-1.8	-1.1	-1.8
Reaction time trials completed	0.5	0.7	1.7	-1.1	-1.1	-0.2	0.6	-0.5	-0.4	-0.6	0.8	1.3	0.9
Reaction time trials AUC	0.4	0.6	1.7	-1.0	-1.0	-0.3	0.4	-0.6	-0.4	-0.5	0.9	1.3	1.0
Run reversals in cocaine runway, females	1.7	1.7	4.6	-0.7	-0.8	-1.1	0.8	-1.2	0.3	-1.2	2.0	1.5	2.1
Run reversals in cocaine runway, males	0.4	0.4	0.7	0.8	0.8	-0.8	-0.8	-0.6	-0.8	0.6	0.3	0.1	0.2
Latency to leave start box in cocaine runway	0.2	0.3	0.6	0.6	0.6	0.3	-0.6	0.3	0.8	0.5	-0.1	-0.7	-0.2
Latency to leave start box in cocaine runway, F	0.1	0.1	0.4	-0.1	-0.1	0.6	0.1	0.4	0.5	-0.1	-0.3	-0.3	-0.3
Latency to leave start box in cocaine runway, M	1.6	1.5	3.6	1.9	1.9	-0.7	-1.9	-0.5	-0.2	1.8	0.1	-0.7	-0.1
Std. dev. time between licks in bursts	1.5	1.8	3.4	0.4	0.4	-1.7	-0.6	-1.8	-1.2	0.3	1.8	1.6	1.8
Total sessions with >9 infusions	1.0	1.1	2.3	1.5	1.5	-1.3	-1.3	-0.8	0.2	1.2	0.8	-0.6	0.5
Short access day 1 total inactive lever presses	0.6	0.6	1.3	1.1	1.0	-1.0	-1.0	-0.6	0.4	0.8	0.7	-0.5	0.5
Short access day 10 total inactive lever presses	2.1	2.3	4.0	1.7	1.7	-2.0	-1.7	-1.9	-1.3	1.3	1.6	0.5	1.3
Short access day 1 total infusions	0.6	0.7	1.3	1.0	1.1	-1.1	-1.0	-0.7	0.2	0.8	0.8	-0.3	0.6
Short access day 10 total infusions	0.4	0.4	2.3	0.6	0.5	-0.3	-0.3	0.2	1.5	0.4	0.3	-1.0	0.2
Short access total infusions	0.4	0.5	1.0	0.8	0.8	-1.0	-0.5	-0.5	0.7	0.4	0.8	-0.4	0.7
Short access day 1 locomotion	0.3	0.3	1.5	-0.0	-0.1	-0.6	0.2	-0.1	1.2	-0.4	0.7	-0.2	0.7
Short access day 10 total locomotion	0.2	0.2	1.7	0.0	-0.0	-0.0	0.2	0.3	1.3	-0.2	0.2	-0.6	0.2
Short access total locomotion	0.4	0.4	2.3	-0.2	-0.3	-0.2	0.5	0.1	1.5	-0.6	0.6	-0.3	0.6
One hour access (0.3 mA shock)	2.0	2.3	4.9	2.1	2.2	-0.3	-2.0	0.2	0.3	2.1	-0.7	-1.9	-1.0
Compulsive drug intake	3.3	3.3	7.5	-1.3	-1.0	-1.9	0.8	-1.9	-1.6	-1.4	2.2	2.7	2.3
One hour access (shock baseline)	4.2	4.9	9.8	2.6	2.5	1.0	-2.1	1.3	0.8	2.7	-2.2	-3.1	-2.5
Social response proportion	0.1	0.1	0.4	-0.6	-0.5	-0.0	0.3	-0.2	0.1	-0.2	0.4	0.5	0.4
Social responses	0.3	0.3	1.0	-0.4	-0.3	-0.5	0.2	-0.6	-1.0	-0.1	0.5	1.0	0.5
Social time	0.4	0.5	1.6	-0.1	0.1	-0.7	-0.2	-0.9	-1.2	-0.1	0.7	1.0	0.7
Soleus weight	1.4	4.2	9.2	2.9	3.0	-1.9	-2.8	-1.5	-1.1	2.9	0.8	-0.5	0.4
Bone: stiffness	1.5	2.4	4.7	-1.3	-1.3	2.2	1.0	2.0	2.1	-0.6	-1.6	-1.3	-1.4
Tibialis anterior weight	5.3	18.2	38.4	-6.2	-6.1	3.7	6.1	2.8	2.5	-6.2	-1.2	1.3	-0.3
Time to tail flick, vehicle, before self-admin	0.8	0.8	2.8	-0.8	-0.6	1.0	0.8	1.1	1.7	-0.8	-0.6	-0.9	-0.5
Time to tail flick, vehicle, after self-admin	0.5	0.5	1.2	-0.6	-0.6	-0.4	0.6	-0.5	0.3	-0.8	1.0	0.8	1.1
Time to tail flick, test, before self-admin	0.6	0.5	1.5	-0.5	-0.4	-0.3	0.3	-0.5	0.8	-0.9	1.2	0.5	1.2
Time to tail flick, test, after self-admin	0.0	0.0	0.1	0.1	0.4	0.0	-0.3	-0.1	-0.3	0.3	-0.0	-0.1	-0.1
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	0.9	0.1	-0.0	-0.7	0.0	-0.9	-0.6	-0.1	0.9	0.9	0.9
Delta time to tail flick, test, before/after SA	0.4	0.4	1.2	0.2	0.1	0.5	0.0	0.5	-0.8	0.4	-1.1	-0.3	-1.1
Tibia length	2.5	7.0	12.2	-2.2	-2.3	3.5	2.3	3.4	2.8	-1.8	-2.9	-2.0	-2.6
Ambulatory time before self-admin	2.5	2.6	4.8	-1.6	-1.6	1.8	1.6	2.2	1.5	-0.9	-1.9	-1.0	-1.7
Ambulatory time after self-admin	0.9	1.0	2.0	-0.6	-0.6	1.4	0.3	1.4	1.0	0.2	-1.3	-0.9	-1.2
Bone: tissue strength	0.2	0.2	0.6	0.1	0.2	-0.4	-0.6	-0.3	-0.3	0.8	0.3	0.1	0.2
Total heroin consumption	2.0	2.3	4.9	-2.2	-2.2	1.5	2.2	0.9	-0.0	-2.1	-0.7	0.9	-0.3
Bone: trabecular number	0.6	1.0	3.0	-1.0	-1.0	1.0	1.0	1.2	1.7	-0.8	-0.6	-0.6	-0.4
Bone: trabecular spacing	0.9	1.2	2.7	0.5	0.5	-1.3	-0.6	-1.5	-1.6	0.6	1.2	1.2	1.1
Bone: trabecular thickness	0.7	0.8	1.8	0.6	0.6	0.6	-0.6	0.9	0.6	0.9	-1.1	-1.3	-1.2
Bone: trabecular tissue density	2.4	3.4	7.4	2.7	2.7	-1.7	-2.3	-1.4	-1.8	2.3	0.4	-0.3	0.0
Water consumed over 24 hours	0.3	0.4	0.9	-0.9	-0.8	-0.1	0.5	-0.3	-0.5	-0.6	0.4	0.9	0.5
Number of responses in last shaping day	0.6	0.6	1.4	0.2	0.2	-0.9	-0.0	-1.1	-0.6	-0.2	1.2	0.9	1.1