Hub : Genes

Lrrn4cl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr1_215175813_215178509 0.04 0.03 2.9e-03 0.01 0.01 0.01 0.01 7.1e-02 1.3e-02 1.6e-02 3.5e-02
2 Adipose intron excision ratio chr1_215175813_215187755 0.14 0.07 6.6e-11 0.08 0.09 0.09 0.09 7.7e-09 1.8e-10 3.9e-10 5.2e-10
3 PL gene expression Lrrn4cl 0.04 0.03 9.0e-07 0.06 0.06 0.06 0.06 7.9e-07 4.4e-07 2.6e-07 3.3e-07
4 Adipose gene expression Lrrn4cl 0.06 0.04 1.9e-05 0.03 0.03 0.01 0.03 9.8e-05 1.5e-04 1.8e-02 1.7e-04
5 Adipose alternative polyA XM_039091425.2 0.26 0.1 0.0e+00 0.18 0.17 0.16 0.18 1.1e-19 1.6e-18 6.4e-18 2.2e-19
6 Adipose intron excision ratio chr1_215194453_215194539 0.16 0.08 6.7e-10 0.06 0.06 0.06 0.06 6.4e-07 1.1e-07 2.7e-07 1.6e-07
7 NAcc gene expression Lrrn4cl 0.02 0.01 1.1e-04 0.03 0.03 0.03 0.03 5.4e-05 3.9e-05 5.0e-05 8.8e-05
8 NAcc alternative polyA XM_039091425.2 0.02 0.01 9.5e-03 0.02 0.01 0.01 0.01 1.0e-03 3.5e-03 6.6e-03 6.8e-03
9 Adipose intron excision ratio chr1_215187888_215194539 0.09 0.05 1.9e-05 0.04 0.04 0.04 0.04 2.6e-05 2.9e-05 2.5e-05 1.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.50.92.3-1.20.9-0.7-0.80.6-0.51.01.50.3
Area under the delay curve0.10.20.5-0.1-0.4-0.2-0.40.40.40.50.5-0.7
BMI with tail2.37.919.4-3.52.1-2.7-2.62.6-0.63.84.40.0
BMI without tail0.31.63.2-0.8-0.1-1.1-1.41.50.81.81.7-1.2
Body weight2.310.119.2-3.32.1-3.8-3.73.90.44.43.5-0.0
Weight adjusted by age0.30.81.5-1.21.1-0.9-0.70.6-0.41.00.90.8
Bone surface2.14.17.5-2.72.4-2.0-1.81.7-1.12.22.41.4
Bone volume1.32.65.3-2.32.1-1.2-1.00.9-1.41.42.11.5
Breakpoint value in progressive ratio session0.71.32.6-1.01.3-1.6-1.51.30.11.2-0.11.0
Number of licking bursts0.00.00.10.0-0.10.0-0.30.30.10.10.20.1
Context. condit. distance diff. score0.20.31.10.5-0.90.40.1-0.20.3-0.10.5-1.0
Locomotion velocity, session 10.60.62.30.7-1.1-0.2-0.40.51.10.3-0.0-1.5
Locomotion distance, session 10.81.01.9-0.3-0.3-1.0-1.31.40.81.20.9-1.2
Locomotion velocity, session 21.72.13.7-1.41.0-1.9-1.91.90.21.91.10.1
Locomotion distance, session 20.40.51.20.2-0.5-0.7-1.11.00.90.70.1-0.9
Locomotion velocity, session 30.70.82.8-0.80.0-0.6-0.90.80.11.21.7-0.7
Locomotion distance, session 30.20.20.60.3-0.6-0.2-0.30.30.80.40.0-0.8
Stereotopy head waving bouts, day 30.30.32.0-0.4-0.00.1-0.30.2-0.60.31.4-0.3
Stereotopy head waving duration, day 30.10.20.7-0.1-0.30.0-0.60.4-0.10.20.8-0.5
Locomotion velocity, session 70.20.20.7-0.40.3-0.1-0.40.3-0.40.30.80.2
Locomotion distance, session 70.20.31.10.3-0.80.1-0.30.10.50.30.6-1.1
Stereotopy head waving bouts, day 70.60.71.3-1.11.1-0.5-0.60.6-1.00.40.90.9
Stereotopy head waving duration, day 71.21.52.2-1.51.3-1.4-1.51.5-0.41.31.10.8
Locomotion velocity, session 80.70.92.11.1-1.4-0.1-0.50.41.30.0-0.7-1.4
Locomotion distance, session 80.20.21.10.0-0.50.4-0.0-0.0-0.2-0.01.1-0.7
Degree of sensitization distance0.40.42.5-0.70.20.1-0.10.0-0.60.41.6-0.2
Degree of sensitization stereotypy1.21.42.8-1.51.7-1.0-0.91.0-1.00.80.91.3
Conditioned locomotion0.40.41.1-0.40.2-0.9-1.01.10.40.90.3-0.1
Cocaine response after cond. corrected0.60.92.81.2-1.60.60.20.01.0-0.4-0.3-1.7
Cocaine response after cond. not corrected0.30.51.40.8-1.00.50.5-0.20.6-0.4-0.2-1.2
Cocaine response before conditioning0.70.82.4-1.11.5-0.50.5-0.4-1.00.20.21.4
Saline control response1.72.45.1-0.70.2-2.1-2.32.21.42.00.3-0.7
Bone: connectivity density1.42.34.1-1.91.3-1.7-1.61.4-0.22.01.90.3
Bone: cortical apparent density0.20.30.80.10.1-0.7-0.90.80.40.2-0.80.2
Bone: cortical area0.81.42.5-1.61.5-1.2-0.90.9-0.71.11.11.1
Bone: cortical porosity0.20.21.10.4-0.00.0-0.00.10.0-0.5-1.00.5
Bone: cortical porosity0.10.20.90.4-0.2-0.2-0.30.30.4-0.2-0.90.1
Bone: cortical thickness1.62.76.0-0.50.4-2.4-2.42.41.71.9-0.7-0.3
Bone: cortical thickness0.60.82.00.6-0.7-0.7-0.80.91.40.6-0.8-1.0
Bone: cortical tissue density0.30.51.20.00.2-0.9-1.11.00.50.4-0.90.2
Condit. Reinf. active minus inactive responses0.60.71.3-0.90.8-1.1-1.00.90.11.10.60.3
Condit. Reinf. active-inactive response ratio0.20.30.6-0.10.1-0.7-0.80.70.60.6-0.2-0.1
Condit. Reinf. active responses1.01.32.7-1.61.5-1.1-0.70.7-0.81.11.31.0
Condit. Reinf. inactive responses0.91.22.6-1.41.40.10.6-0.4-1.60.11.51.3
Incentive salience index mean0.91.12.1-1.31.0-1.3-1.01.1-0.01.41.20.2
Condit. Reinf. lever presses0.81.32.6-1.51.1-1.2-0.91.1-0.41.41.60.3
Condit. Reinf. active minus inactive responses0.40.61.6-0.50.90.40.6-0.6-1.2-0.60.01.3
Condit. Reinf. active-inactive response ratio1.22.05.5-1.21.60.81.0-1.0-2.4-0.81.12.0
Condit. Reinf. active responses0.10.10.3-0.40.6-0.3-0.20.2-0.30.10.00.5
Condit. Reinf. inactive responses0.60.92.60.8-1.0-0.5-0.60.61.60.4-0.8-1.3
Condit. Reinf. lever presses0.81.12.3-1.51.4-1.0-0.70.8-0.61.11.10.9
Condit. Reinf. lever reinforcers received0.20.20.6-0.60.8-0.5-0.40.4-0.30.3-0.00.7
Conditioned reinforcement - actives0.41.74.7-1.01.50.61.1-1.1-2.0-0.80.22.2
Conditioned reinforcement - inactives0.71.94.8-1.61.80.30.7-0.7-2.2-0.11.31.9
Conditioned locomotion1.01.53.00.1-0.11.71.7-1.7-1.5-1.30.60.3
Patch foraging indifference point 0 sec0.20.61.5-0.60.4-1.0-1.21.20.31.00.5-0.2
Patch foraging indifference point AUC0.81.94.6-1.72.1-1.3-0.90.8-1.10.80.42.1
Delay disc. indifference point, 0s delay0.30.31.20.4-0.90.60.3-0.20.3-0.00.5-1.1
Delay disc. indifference point, 16s delay0.20.30.6-0.80.6-0.3-0.20.2-0.50.50.80.4
Delay disc. indifference point, 2s delay0.20.30.6-0.30.20.60.6-0.7-0.7-0.20.80.1
Delay disc. indifference point, 24s delay0.20.30.80.3-0.6-0.3-0.50.50.80.50.2-0.9
Delay disc. indifference point, 4s delay0.80.82.00.2-0.8-0.5-1.00.91.11.00.4-1.4
Delay disc. indifference point, 8s delay0.40.61.71.1-1.30.60.1-0.10.8-0.3-0.4-1.2
Indifference point function ln k1.54.610.92.6-3.32.11.5-1.41.6-1.4-0.7-3.2
Indifference point function log k1.54.610.92.6-3.32.11.5-1.41.6-1.4-0.7-3.2
Patch foraging total patch changes 0 sec0.30.81.8-0.1-0.2-1.0-1.31.30.91.00.0-0.7
Patch foraging total patch changes 12 sec3.54.79.0-2.12.1-3.0-3.02.80.22.50.81.1
Patch foraging total patch changes 18 sec0.30.61.0-0.81.0-1.0-0.90.9-0.30.6-0.10.9
Patch foraging total patch changes 24 sec1.65.410.4-2.11.6-3.1-3.23.10.53.01.50.5
Patch foraging total patch changes 6 sec0.81.32.9-0.80.5-1.5-1.71.60.51.50.7-0.2
Patch foraging time to switch 0 sec0.31.32.8-1.71.6-0.6-0.30.4-1.30.81.61.1
Patch foraging water rate 0 sec0.30.91.91.4-1.30.80.5-0.50.9-0.9-1.1-1.0
Patch foraging water rate 12 sec1.03.98.42.6-2.91.81.2-1.21.8-1.4-1.4-2.5
Patch foraging water rate 18 sec1.12.47.61.8-2.50.80.1-0.22.0-0.2-0.4-2.8
Patch foraging water rate 24 sec1.31.83.61.8-1.91.20.9-1.01.0-1.2-1.2-1.6
Patch foraging water rate 6 sec2.13.17.22.4-2.71.40.8-0.71.8-1.2-1.4-2.3
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.1-0.0-0.2-0.20.10.10.30.3-0.3
Distance traveled before self-admin1.22.74.8-2.22.1-1.7-1.41.4-1.01.61.41.5
Distance traveled after self-admin0.20.30.5-0.50.7-0.7-0.60.6-0.00.4-0.20.7
Extensor digitorum longus weight3.815.228.1-3.62.5-5.2-5.25.21.35.32.80.2
Bone: elastic displacement0.91.12.31.5-1.40.60.4-0.41.1-0.7-1.4-1.0
Bone: elastic work1.01.32.90.4-0.7-1.1-1.31.31.71.2-0.4-1.3
Bone: endosteal estimation0.92.36.4-1.00.71.51.6-1.6-2.2-0.62.50.7
Bone: endosteal perimeter1.74.110.2-1.41.31.92.0-2.1-3.2-1.22.61.7
Epididymis fat weight0.62.96.7-1.11.11.71.8-2.0-2.6-1.01.91.4
Delta time in closed arm before/after self-admin2.32.25.00.6-1.4-1.1-1.61.52.11.40.2-2.2
Delta time in open arm before/after self-admin2.12.55.6-2.12.4-1.5-1.01.0-1.31.11.02.1
Diff in mean of infusions in LGA sessions1.01.74.1-0.60.5-1.9-2.01.90.91.50.0-0.1
Delay discount exponential model param0.10.20.50.10.30.20.5-0.4-0.4-0.5-0.50.7
Extinction: sum of active levers before priming1.82.84.7-1.81.5-2.2-2.12.10.12.11.20.6
Active lever presses in extinction session 62.32.44.6-2.02.1-1.8-1.31.3-0.81.40.81.7
Bone: final force1.32.23.7-1.91.6-1.7-1.41.4-0.51.81.70.7
Bone: final moment1.32.23.5-1.91.5-1.7-1.41.5-0.41.81.60.6
Food consumed during 24 hour testing period0.10.20.3-0.00.30.50.5-0.5-0.5-0.5-0.10.5
Glucose1.11.84.60.7-0.92.11.8-1.9-0.8-1.40.7-0.4
Heart weight0.50.83.00.3-1.10.70.3-0.20.50.31.3-1.7
Delay discount hyperbolic model param0.10.10.30.10.30.10.3-0.2-0.2-0.4-0.60.6
Intermittent access intake day 1-15 change0.42.43.80.10.71.51.9-1.9-1.9-1.9-0.71.8
Intermittent access intake escalation0.52.94.60.10.81.72.1-2.1-2.0-2.1-0.82.0
Intermittent access intake escalation 21.01.74.2-0.61.20.81.2-1.3-1.9-1.2-0.22.0
Intermitt. access day 1 inactive lever presses0.11.22.20.40.21.21.4-1.4-1.1-1.5-0.81.0
Intermitt. access day 15 inactive lever presses0.52.85.8-2.42.4-0.7-0.20.2-2.10.92.02.1
Intermitt. access escalation Index0.30.91.61.2-1.31.00.7-0.70.6-0.8-0.7-1.0
Intermittent access day 1 total infusions0.61.87.2-1.50.90.60.8-0.9-1.90.22.70.4
Intermittent access day 15 total infusions1.74.29.2-0.71.02.22.6-2.7-3.0-1.91.11.8
Intermittent access terminal intake (last 3 days)2.23.810.4-1.91.91.11.7-1.7-3.2-0.72.22.1
Intermittent access total infusions2.12.46.4-1.41.21.11.5-1.5-2.5-0.52.11.2
Intermittent access day 1 locomotion0.50.94.5-1.20.70.10.3-0.3-1.20.52.10.1
Intermittent access day 15 total locomotion0.72.66.8-1.91.90.40.9-0.9-2.6-0.12.01.9
Intermittent access total locomotion3.84.511.2-2.72.40.40.9-1.0-3.30.23.22.1
Intermittent access standard deviation0.21.12.2-0.10.51.21.4-1.5-1.4-1.2-0.11.1
Left kidney weight0.11.23.3-1.00.80.81.0-0.9-1.6-0.21.80.7
Right kidney weight0.10.81.9-0.80.80.60.6-0.7-1.3-0.21.40.8
Cocaine induced anxiety0.10.31.1-0.50.8-0.10.2-0.1-0.6-0.1-0.21.1
Post-drug Anxiety0.20.30.6-0.70.8-0.5-0.30.4-0.30.50.10.7
Baseline Anxiety0.40.71.60.2-0.7-0.6-1.00.91.20.90.2-1.3
Tail length0.21.22.60.5-0.6-1.1-1.31.51.60.8-0.9-0.8
Length with tail0.73.27.8-1.00.7-2.5-2.62.81.32.30.4-0.2
Length without tail1.05.310.9-1.51.0-3.2-3.33.31.53.11.0-0.4
Times rat made contact with spout0.60.71.70.8-0.9-0.3-0.60.71.30.2-0.9-0.9
Lifetime Intake1.01.33.2-0.90.61.01.2-1.3-1.7-0.41.80.4
Liver weight, left0.71.32.21.2-1.01.51.4-1.4-0.0-1.4-0.8-0.3
Liver weight, right0.91.63.01.4-1.71.61.3-1.30.4-1.1-0.1-1.5
Locomotor activity1.82.86.52.3-2.61.10.6-0.41.9-0.9-1.5-2.2
Locomotor testing distance1.33.27.62.4-2.81.10.7-0.52.1-0.8-1.3-2.6
Locomotor testing rearing0.62.35.02.0-2.21.31.0-0.91.4-1.0-1.1-2.0
Locomotion in novel chamber1.21.63.60.10.11.71.9-1.9-1.5-1.40.30.7
Locomotion in novel chamber post-restriction0.51.63.30.6-0.11.81.5-1.7-1.3-1.8-0.50.9
Fecal boli incidents, locomotor time 10.51.23.0-0.81.30.50.9-1.0-1.7-0.80.21.7
Change in fecal boli incidents, locomotor task1.21.33.21.5-1.81.00.5-0.51.0-0.7-0.6-1.6
Time >=10cm from walls, locomotor time 12.12.66.5-0.81.21.51.8-1.8-2.6-1.41.01.8
Bouts of movement, locomotor time 10.40.52.80.40.4-0.4-0.20.10.2-0.4-1.70.9
Total resting periods, locomotor time 10.30.41.60.00.7-0.4-0.10.0-0.1-0.3-1.21.2
Rest time, locomotor task time 10.91.42.91.0-0.51.51.5-1.5-0.6-1.7-1.20.4
Distance moved, locomotor task time 10.10.30.7-0.60.3-0.6-0.50.60.10.80.9-0.2
Vertical activity count, locomotor time 10.00.20.50.5-0.60.70.6-0.6-0.0-0.5-0.1-0.4
Time >=10cm from walls, locomotor time 20.30.92.7-0.71.20.20.6-0.7-1.4-0.6-0.01.6
Bouts of movement, locomotor time 20.20.71.5-0.70.7-1.2-1.01.10.41.00.00.3
Total resting periods, locomotor time 20.10.30.6-0.50.6-0.8-0.60.70.10.60.00.4
Rest time, locomotor task time 21.22.04.21.3-1.02.01.8-1.9-0.6-1.9-0.8-0.2
Distance moved, locomotor task time 20.20.20.7-0.10.3-0.8-0.60.60.50.5-0.40.2
Vertical activity count, locomotor time 20.30.81.81.2-1.1-0.0-0.10.31.3-0.2-1.3-0.9
Light reinforcement 10.00.10.40.4-0.20.30.3-0.20.2-0.4-0.60.0
Light reinforcement 21.12.46.0-1.62.00.51.1-0.9-2.4-0.51.22.3
Bone: marrow area1.02.46.0-0.90.51.71.7-1.7-2.2-0.82.40.6
Bone: maximum diameter0.81.73.2-1.81.8-0.4-0.10.1-1.70.51.71.6
Bone: maximum force2.44.79.2-3.02.5-2.0-1.71.6-1.22.42.91.3
Bone: maximum moment2.44.58.5-2.92.4-2.0-1.71.6-1.12.42.81.2
Mean time between licks in bursts0.31.74.60.9-1.5-0.6-0.80.82.10.9-0.3-2.1
Mean num. licks in bursts0.10.31.00.7-0.60.20.2-0.20.7-0.3-1.0-0.7
Cd content in liver0.50.61.5-0.10.40.90.8-0.8-1.2-1.00.20.9
Co content in liver2.02.34.82.2-2.00.80.5-0.51.6-1.1-2.2-1.6
Cu content in liver0.10.20.50.5-0.40.1-0.0-0.10.5-0.2-0.7-0.4
Fe content in liver0.00.00.00.1-0.20.1-0.00.00.1-0.00.2-0.2
K content in liver0.30.30.7-0.60.3-0.6-0.60.60.20.80.8-0.2
Mg content in liver0.30.31.00.0-0.5-0.1-0.50.50.50.50.6-1.0
Mn content in liver2.12.43.5-1.81.7-1.9-1.81.6-0.31.81.11.1
Na content in liver0.30.40.7-0.80.7-0.7-0.50.4-0.20.70.70.3
Rb content in liver1.92.23.81.9-2.01.81.4-1.30.6-1.5-0.9-1.4
Se content in liver0.60.81.6-1.11.3-0.20.0-0.1-1.20.21.01.3
Sr content in liver2.62.24.2-1.41.3-2.0-2.12.10.21.80.40.8
Zn content in liver1.82.14.3-1.30.9-1.9-2.12.00.41.90.80.1
Bone: minimum diameter1.12.16.1-1.41.11.11.1-1.2-2.2-0.32.51.0
Time in familiar zone, hab. session 10.10.10.4-0.40.2-0.20.00.20.00.40.6-0.2
Time in novel zone, hab. session 11.11.32.21.5-1.41.20.9-1.20.6-1.2-1.1-0.9
Total zone transitions, hab. session 10.30.41.4-0.10.0-0.7-1.21.00.40.5-0.0-0.1
Total locomotion distance, hab. session 10.20.31.0-0.70.60.1-0.30.1-0.90.01.00.5
Locomotion velocity, hab. session 10.40.50.8-0.90.8-0.5-0.90.6-0.70.50.90.6
Time in familiar zone, hab. session 21.01.12.01.3-1.20.70.9-0.51.1-0.7-1.4-1.1
Time in novel zone, hab. session 20.70.71.6-1.00.7-0.8-1.00.7-0.41.01.30.3
Total zone transitions, hab. session 21.11.53.1-0.70.2-1.5-1.61.80.81.60.9-0.8
Total locomotion distance, hab. session 20.30.30.8-0.50.1-0.5-0.70.70.10.70.9-0.5
Locomotion velocity, hab. session 20.20.31.2-0.70.3-0.4-0.50.5-0.40.61.1-0.1
Novel to familiar place preference ratio1.41.82.8-1.71.6-1.5-1.51.2-0.61.41.21.1
Novelty place preference0.91.22.0-1.41.4-1.1-1.10.8-0.71.11.01.1
Time in novel zone, NPP test0.91.11.9-1.41.3-1.1-1.10.9-0.51.21.00.9
Total zone transitions, NPP test0.91.43.4-0.50.1-1.5-1.71.80.81.40.5-0.6
Total locomotion distance, NPP test0.20.30.5-0.0-0.3-0.5-0.70.70.40.50.4-0.7
Locomotion velocity, NPP test0.10.20.40.0-0.2-0.4-0.60.60.30.30.2-0.5
Intraocular pressure0.20.30.90.5-0.00.40.6-0.4-0.1-0.7-0.90.4
Delta distance traveled before/after self-admin1.31.53.11.7-1.80.70.4-0.31.5-0.7-1.3-1.5
Delta ambulatory time before/after self-admin1.11.83.71.9-1.91.00.6-0.51.4-0.9-1.5-1.5
Parametrial fat weight1.43.37.6-0.80.92.02.1-2.1-2.8-1.41.81.4
Pavlov. Cond. lever latency0.91.12.11.4-1.11.10.7-1.00.4-1.3-1.5-0.4
Pavlov. Cond. magazine entry latency1.62.14.5-2.12.0-1.0-0.50.5-1.31.21.81.4
Pavlov. Cond. change in total contacts1.61.73.9-1.82.0-0.6-0.10.2-1.60.51.21.8
Pavlov. Cond. index score0.81.12.3-1.51.5-0.9-0.40.5-0.80.91.11.1
Pavlov. Cond. latency score0.60.81.8-1.31.2-0.8-0.40.5-0.60.91.20.7
Pavlov. Cond. lever contacts0.60.71.7-1.20.9-0.7-0.40.6-0.40.91.30.3
Pavlov. Cond. magazine entry number0.91.12.81.5-1.71.00.5-0.50.9-0.8-0.7-1.4
Pavlov. Cond. intertrial magazine entries0.30.31.2-0.30.8-0.20.2-0.3-0.6-0.3-0.51.1
Pavlov. Cond. lever-magazine prob. diff.1.11.32.9-1.71.7-0.9-0.50.6-1.00.91.21.3
Pavlov. Cond. response bias1.11.43.1-1.71.8-1.0-0.60.6-1.01.01.21.3
Pavlov. Cond. lever latency0.50.61.41.2-1.10.70.4-0.50.5-0.8-0.9-0.6
Pavlov. Cond. magazine entry latency2.53.56.9-2.22.1-2.6-1.92.0-0.02.30.91.0
Pavlov. Cond. change in total contacts0.92.25.3-2.22.3-1.3-0.70.7-1.21.21.21.7
Pavlov. Cond. index score1.82.85.5-2.42.3-1.9-1.11.3-0.81.81.41.5
Pavlov. Cond. latency score1.82.85.7-2.42.4-1.8-1.11.2-1.01.71.51.5
Pavlov. Cond. lever contacts0.40.51.3-1.11.1-0.7-0.20.3-0.50.70.60.7
Pavlov. Cond. magazine entry number4.45.710.42.9-2.83.22.4-2.60.3-2.8-1.3-1.5
Pavlov. Cond. intertrial magazine entries0.61.22.81.0-0.61.51.3-1.3-0.6-1.7-0.90.3
Pavlov. Cond. lever-magazine prob. diff.1.93.05.8-2.42.4-2.0-1.21.4-0.81.91.31.5
Pavlov. Cond. response bias1.21.73.1-1.81.6-1.6-1.11.2-0.31.61.00.8
Time in closed arm before self-admin0.50.82.0-0.91.20.40.6-0.6-1.4-0.30.61.4
Time in closed arm after self-admin0.70.81.41.0-1.11.20.9-0.90.4-0.8-0.4-0.9
Time in open arm before self-admin3.34.09.82.6-3.10.90.1-0.12.6-0.6-1.4-3.1
Time in open arm after self-admin0.50.61.20.2-0.3-1.0-1.11.11.00.7-0.3-0.6
Bone: periosteal estimation0.92.16.1-1.91.70.10.4-0.4-2.10.42.51.4
Bone: periosteal perimeter0.81.53.4-1.61.60.10.3-0.3-1.80.21.71.5
Bone: post-yield work2.13.79.9-2.52.20.30.7-0.7-2.80.43.11.8
Progressive ratio test 1 active lever presses0.20.41.0-0.40.40.60.8-0.8-1.0-0.40.70.4
Progressive ratio test 1 breakpoint0.30.51.2-0.40.40.60.8-0.8-1.1-0.40.70.6
Progressive ratio test 1 inactive lever presses0.30.81.5-1.21.0-0.9-0.70.6-0.51.01.20.5
Progressive ratio test 2 active lever presses1.42.05.4-1.11.31.01.4-1.4-2.3-0.81.21.6
Progressive ratio test 2 breakpoint1.52.05.4-1.21.30.91.4-1.4-2.3-0.71.21.6
Progressive ratio test 2 inactive lever presses0.72.36.3-1.51.60.81.3-1.3-2.5-0.61.41.9
Incentive Sensitization - Responses0.72.04.3-2.11.9-0.7-0.30.3-1.60.91.81.5
Incentive Sensitization - Breakpoint0.92.04.2-2.11.9-0.6-0.20.2-1.70.81.81.6
Sum of active levers in priming session hrs 5-62.22.17.3-1.52.3-0.9-0.40.3-1.50.1-0.22.7
Progressive ratio0.20.72.1-1.10.90.10.3-0.1-1.20.21.50.8
Food seeking constrained by brief footshock0.10.10.30.4-0.50.20.10.00.4-0.1-0.0-0.6
Seeking ratio, punishment vs. effort0.61.33.01.4-1.6-0.0-0.40.31.70.0-1.0-1.7
Retroperitoneal fat weight1.77.817.61.8-1.84.24.0-4.0-1.7-3.30.4-0.6
Reaction time number correct0.10.51.50.3-0.5-0.7-0.70.61.20.7-0.3-0.7
Reaction time mean minus median0.31.76.0-1.42.2-0.5-0.20.1-1.60.0-0.12.5
Reaction time mean minus median AUC0.10.62.2-0.41.0-0.20.0-0.1-0.6-0.3-1.01.5
Reaction time num false alarms1.32.24.92.0-2.20.30.0-0.02.0-0.4-1.4-2.2
Reaction time num false alarms AUC1.12.45.71.9-2.1-0.2-0.60.62.40.1-1.5-2.2
Reaction time trials correct on left0.10.51.50.3-0.5-0.7-0.70.61.20.7-0.3-0.7
Reaction time trials on left0.20.51.60.3-0.5-0.7-0.70.71.30.7-0.3-0.7
Reaction time mean0.40.82.3-0.61.20.20.6-0.6-1.3-0.6-0.51.5
Reaction time mean AUC0.40.92.3-0.61.20.30.8-0.8-1.3-0.7-0.51.5
Median of all reaction times0.30.41.0-0.60.90.10.5-0.4-1.0-0.3-0.21.0
Reaction time omissions0.20.30.7-0.20.6-0.6-0.40.50.00.1-0.90.8
Reaction time false alarm rate0.81.12.51.4-1.60.20.00.11.3-0.3-1.0-1.6
Reaction time premature initiation rate2.64.18.1-1.00.0-2.4-2.62.61.92.81.4-1.5
Reaction time premature initiations1.64.88.8-0.6-0.3-2.7-2.92.92.63.00.7-1.7
Std. dev. reaction times0.30.93.1-0.31.10.30.6-0.6-1.1-0.8-1.01.8
Reaction time trials completed0.20.51.60.3-0.5-0.7-0.70.71.30.7-0.3-0.7
Reaction time trials AUC0.10.51.70.3-0.6-0.6-0.70.61.30.7-0.3-0.8
Run reversals in cocaine runway, females1.21.33.70.0-0.9-0.7-1.01.11.31.31.2-1.9
Run reversals in cocaine runway, males0.40.40.70.9-0.70.70.4-0.50.2-0.8-0.8-0.3
Latency to leave start box in cocaine runway0.20.30.8-0.20.00.70.7-0.7-0.7-0.30.90.2
Latency to leave start box in cocaine runway, F0.10.10.3-0.40.2-0.1-0.10.0-0.20.30.60.1
Latency to leave start box in cocaine runway, M1.01.02.30.5-0.61.51.5-1.4-0.7-1.20.3-0.0
Std. dev. time between licks in bursts0.61.23.31.3-1.70.30.1-0.11.6-0.0-0.7-1.8
Total sessions with >9 infusions0.40.51.10.1-0.31.01.0-1.1-0.6-0.70.5-0.1
Short access day 1 total inactive lever presses0.10.21.0-0.4-0.00.20.2-0.1-0.30.31.0-0.4
Short access day 10 total inactive lever presses0.10.50.90.9-0.80.80.7-0.70.2-0.9-0.8-0.5
Short access day 1 total infusions0.40.81.80.3-0.61.31.3-1.3-0.6-0.80.5-0.4
Short access day 10 total infusions0.61.04.0-1.10.60.50.7-0.7-1.40.22.00.2
Short access total infusions0.40.51.8-0.2-0.40.80.8-0.8-0.6-0.21.3-0.7
Short access day 1 locomotion0.20.40.9-0.50.30.50.7-0.7-0.9-0.30.80.3
Short access day 10 total locomotion0.31.23.6-1.61.2-0.2-0.00.0-1.40.61.90.8
Short access total locomotion0.50.82.3-1.10.80.30.4-0.5-1.40.11.50.6
One hour access (0.3 mA shock)1.21.43.9-0.90.81.11.3-1.4-2.0-0.71.21.0
Compulsive drug intake1.31.95.31.1-1.3-0.9-1.31.32.30.7-1.2-1.6
One hour access (shock baseline)1.53.99.6-0.91.22.02.4-2.5-3.1-1.71.21.9
Social response proportion0.00.00.10.1-0.2-0.00.1-0.00.40.2-0.1-0.4
Social responses0.30.41.50.8-0.6-0.2-0.20.31.0-0.1-1.2-0.5
Social time0.40.61.71.0-0.90.1-0.20.31.0-0.3-1.3-0.7
Soleus weight1.64.78.42.3-2.02.92.8-2.7-0.3-2.8-1.1-0.8
Bone: stiffness1.11.94.1-2.02.0-0.9-0.60.5-1.40.91.51.7
Tibialis anterior weight5.218.034.4-3.93.3-5.9-5.75.81.05.42.01.3
Time to tail flick, vehicle, before self-admin0.50.71.9-1.20.9-0.3-0.40.2-0.90.61.40.5
Time to tail flick, vehicle, after self-admin0.20.41.0-0.4-0.1-0.6-0.70.80.40.91.0-0.7
Time to tail flick, test, before self-admin0.80.92.9-0.6-0.2-0.5-1.00.90.31.21.7-1.0
Time to tail flick, test, after self-admin0.20.30.8-0.60.8-0.10.0-0.2-0.7-0.00.10.9
Delta time to tail flick, vehicle, before/after SA0.30.30.70.2-0.4-0.6-0.60.70.80.50.0-0.8
Delta time to tail flick, test, before/after SA0.60.82.6-0.00.90.00.5-0.5-0.6-0.8-1.41.6
Tibia length1.95.411.2-3.13.4-2.0-1.71.7-2.01.61.82.9
Ambulatory time before self-admin0.92.75.6-2.22.4-1.5-1.11.1-1.31.31.31.9
Ambulatory time after self-admin0.20.30.9-0.80.9-0.3-0.10.2-0.60.20.30.9
Bone: tissue strength0.40.40.70.8-0.80.70.7-0.60.5-0.6-0.5-0.7
Total heroin consumption3.13.78.1-1.31.4-2.8-2.82.70.92.2-0.20.8
Bone: trabecular number1.01.83.8-1.71.3-1.3-1.31.1-0.51.61.90.4
Bone: trabecular spacing1.11.63.01.7-1.60.81.0-0.81.2-1.0-1.7-1.2
Bone: trabecular thickness0.30.51.2-0.50.70.50.5-0.6-1.1-0.40.51.0
Bone: trabecular tissue density2.74.79.22.5-1.82.62.5-2.4-0.2-3.0-2.2-0.4
Water consumed over 24 hours0.30.51.10.2-0.3-0.7-0.91.01.10.7-0.4-0.5
Number of responses in last shaping day0.30.41.10.4-0.7-0.4-0.50.61.00.5-0.1-1.0