Hub : Genes

Dcaf12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Dcaf12 0.19 0.11 9.0e-10 0.08 0.08 0.11 0.11 3.6e-08 4.3e-08 1.5e-10 2.7e-10
2 PL gene expression Dcaf12 0.05 0.04 8.4e-04 0.02 0.03 0.03 0.03 1.3e-03 4.0e-04 1.9e-04 2.6e-04
3 NAcc intron excision ratio chr5_61259133_61261619 0.02 0.02 9.4e-03 0.01 0 0.01 0.01 1.1e-02 1.3e-01 2.7e-02 1.4e-02
4 Adipose alternative polyA NM_001427703.1 0.04 0.03 1.8e-03 0.02 0.01 0.02 0.02 2.2e-03 7.6e-03 5.3e-03 3.2e-03
5 Adipose alternative polyA XM_063288402.1 0.04 0.03 1.9e-03 0.02 0.01 0.02 0.02 2.4e-03 7.1e-03 5.0e-03 2.9e-03
6 NAcc gene expression Dcaf12 0.04 0.03 1.5e-04 0.03 0.01 0.02 0 1.3e-05 1.9e-03 2.8e-04 6.5e-02
7 IC gene expression Dcaf12 0.17 0.12 2.4e-03 0.02 0.02 0 0.03 3.9e-02 3.4e-02 2.8e-01 3.2e-02
8 IL gene expression Dcaf12 0.21 0.14 2.5e-03 0.11 0.1 0.08 0.05 1.5e-03 2.8e-03 5.9e-03 2.1e-02
9 BLA gene expression Dcaf12 0.17 0.1 1.3e-05 0.11 0.09 0.08 0.11 2.8e-06 1.1e-05 5.3e-05 1.8e-06
10 Liver mRNA stability Dcaf12 0.04 0.03 5.2e-05 0.01 0.04 0.04 0.03 7.4e-03 8.3e-05 7.0e-05 1.1e-04
11 NAcc mRNA stability Dcaf12 0.02 0.01 2.6e-03 0.02 0.01 0.01 0.01 8.0e-04 3.5e-03 1.3e-02 6.1e-03
12 RMTg isoform ratio XM_063288402.1 0.29 0.16 8.9e-05 0.15 0.08 0.17 0.14 8.5e-05 3.9e-03 3.4e-05 1.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.11.92.81.51.61.01.2-1.21.51.51.71.61.61.1-0.7
Area under the delay curve0.81.01.6-0.7-1.1-0.8-0.90.9-1.3-1.0-1.2-1.3-1.1-0.51.0
BMI with tail1.03.65.82.41.81.92.0-2.02.02.22.21.91.70.5-1.1
BMI without tail1.44.26.92.62.02.22.2-2.22.32.22.32.11.60.2-1.5
Body weight2.29.516.24.03.13.73.7-3.73.23.23.02.71.3-1.2-2.7
Weight adjusted by age0.20.31.50.40.20.60.6-0.6-0.10.1-0.3-0.2-0.8-1.2-0.4
Bone surface0.51.02.01.41.21.11.0-1.01.11.01.11.00.70.0-0.6
Bone volume0.51.01.61.21.20.90.9-0.91.11.11.11.11.00.5-0.5
Breakpoint value in progressive ratio session2.12.57.8-0.5-0.9-0.5-0.40.4-1.9-1.4-2.2-1.8-2.8-2.31.3
Number of licking bursts4.06.69.23.03.02.82.6-2.62.82.92.82.82.10.3-1.7
Context. condit. distance diff. score0.10.10.3-0.4-0.4-0.4-0.50.5-0.2-0.3-0.1-0.20.10.40.3
Locomotion velocity, session 11.81.911.70.70.00.90.8-0.8-0.6-0.4-0.4-0.7-2.7-3.4-0.4
Locomotion distance, session 10.50.63.70.5-0.00.60.5-0.5-0.2-0.2-0.1-0.4-1.4-1.9-0.3
Locomotion velocity, session 21.61.92.71.51.41.31.3-1.31.61.51.61.61.30.6-1.0
Locomotion distance, session 21.41.93.51.91.31.81.7-1.71.21.21.31.0-0.1-1.4-1.2
Locomotion velocity, session 30.30.42.10.40.30.40.5-0.5-0.3-0.1-0.1-0.1-1.1-1.5-0.3
Locomotion distance, session 31.31.52.51.61.21.51.5-1.51.01.11.00.9-0.1-1.1-1.2
Stereotopy head waving bouts, day 30.30.41.70.31.00.50.5-0.5-0.20.1-0.60.1-0.8-1.3-0.1
Stereotopy head waving duration, day 30.10.21.00.11.00.20.2-0.2-0.10.2-0.50.3-0.2-0.50.2
Locomotion velocity, session 70.00.00.1-0.2-0.1-0.3-0.20.2-0.3-0.2-0.3-0.1-0.20.00.3
Locomotion distance, session 70.10.20.40.60.30.40.5-0.50.00.30.20.2-0.3-0.6-0.3
Stereotopy head waving bouts, day 71.71.93.61.51.91.61.6-1.61.51.41.11.40.5-0.5-1.2
Stereotopy head waving duration, day 71.21.43.11.21.81.31.3-1.31.31.30.91.30.6-0.3-1.0
Locomotion velocity, session 80.30.32.00.30.10.40.3-0.3-0.3-0.3-0.1-0.3-1.2-1.4-0.1
Locomotion distance, session 80.20.31.50.50.10.60.4-0.40.00.00.2-0.1-0.8-1.2-0.4
Degree of sensitization distance0.60.61.0-1.0-0.7-1.0-0.90.9-0.9-0.8-0.9-0.7-0.20.40.8
Degree of sensitization stereotypy1.61.72.51.41.61.41.4-1.41.51.41.31.40.80.0-1.2
Conditioned locomotion0.20.31.70.2-0.10.30.2-0.2-0.3-0.3-0.4-0.4-0.9-1.3-0.2
Cocaine response after cond. corrected1.51.84.6-1.1-1.0-0.9-0.80.8-1.8-1.3-1.8-1.4-2.1-1.70.7
Cocaine response after cond. not corrected1.51.75.0-1.0-0.8-0.7-0.60.6-1.6-1.2-1.7-1.3-2.2-2.00.6
Cocaine response before conditioning0.70.81.51.01.00.90.9-0.91.20.91.11.00.80.1-0.6
Saline control response1.31.72.81.51.71.61.7-1.71.01.10.81.0-0.2-1.3-1.1
Bone: connectivity density0.50.81.60.90.90.40.5-0.51.00.81.11.01.31.2-0.3
Bone: cortical apparent density0.30.42.0-0.1-0.0-0.1-0.20.20.60.20.60.41.21.4-0.1
Bone: cortical area2.74.25.92.22.41.91.7-1.72.42.32.22.42.41.2-1.1
Bone: cortical porosity0.10.10.2-0.5-0.2-0.5-0.40.4-0.3-0.2-0.4-0.20.10.40.4
Bone: cortical porosity0.00.00.10.10.30.10.2-0.20.10.2-0.00.20.10.0-0.1
Bone: cortical thickness1.32.25.71.11.40.90.8-0.81.81.61.61.82.41.9-0.6
Bone: cortical thickness0.30.31.8-0.5-0.3-0.5-0.60.60.0-0.2-0.2-0.00.91.30.5
Bone: cortical tissue density0.20.31.6-0.2-0.1-0.2-0.30.30.50.10.50.31.11.3-0.0
Condit. Reinf. active minus inactive responses0.40.50.70.70.60.80.8-0.80.90.70.80.70.50.0-0.7
Condit. Reinf. active-inactive response ratio0.50.60.9-0.9-0.9-0.9-0.90.9-0.7-0.8-0.6-0.7-0.20.30.7
Condit. Reinf. active responses2.42.93.92.01.81.91.9-1.92.01.81.91.81.20.1-1.5
Condit. Reinf. inactive responses2.83.44.62.12.01.91.9-1.92.12.02.02.01.60.5-1.4
Incentive salience index mean3.54.26.22.52.12.52.4-2.42.22.22.22.01.0-0.6-1.8
Condit. Reinf. lever presses8.011.217.44.23.54.14.0-4.03.43.43.53.11.1-1.6-2.8
Condit. Reinf. active minus inactive responses0.40.61.10.80.60.70.7-0.70.90.81.10.90.80.4-0.6
Condit. Reinf. active-inactive response ratio0.10.10.5-0.0-0.2-0.2-0.20.20.20.00.30.20.50.70.0
Condit. Reinf. active responses1.52.13.41.81.31.61.5-1.51.71.51.81.51.30.2-1.2
Condit. Reinf. inactive responses2.93.75.62.21.82.01.8-1.82.42.12.32.02.00.7-1.5
Condit. Reinf. lever presses2.94.05.71.91.91.61.8-1.82.42.22.32.22.41.5-1.6
Condit. Reinf. lever reinforcers received1.92.63.92.01.51.71.7-1.71.91.72.01.71.30.2-1.4
Conditioned reinforcement - actives0.40.61.40.91.20.70.7-0.71.11.00.40.90.50.4-0.1
Conditioned reinforcement - inactives0.10.20.90.50.90.30.5-0.50.40.60.20.30.0-0.10.4
Conditioned locomotion0.20.20.70.60.90.40.5-0.50.30.6-0.30.5-0.1-0.2-0.2
Patch foraging indifference point 0 sec0.81.47.71.00.40.81.1-1.1-0.6-0.1-0.5-0.6-2.1-2.8-0.1
Patch foraging indifference point AUC4.56.49.13.02.62.92.9-2.92.62.72.72.51.2-0.8-2.4
Delay disc. indifference point, 0s delay1.01.11.8-0.8-1.1-0.8-1.01.0-1.1-1.1-1.3-1.3-1.1-0.61.3
Delay disc. indifference point, 16s delay1.31.53.3-0.5-0.8-0.9-0.60.6-1.6-1.3-1.5-1.5-1.8-1.31.3
Delay disc. indifference point, 2s delay0.30.30.80.40.70.30.2-0.20.50.60.50.60.90.70.0
Delay disc. indifference point, 24s delay0.40.41.1-0.5-1.0-0.8-0.60.6-0.8-0.7-0.5-0.8-0.4-0.00.6
Delay disc. indifference point, 4s delay0.20.20.5-0.5-0.7-0.5-0.50.5-0.6-0.4-0.7-0.6-0.30.10.1
Delay disc. indifference point, 8s delay0.10.10.2-0.0-0.4-0.1-0.30.3-0.4-0.2-0.2-0.4-0.10.00.3
Indifference point function ln k1.42.53.4-1.8-1.8-1.7-1.71.7-1.6-1.8-1.7-1.8-1.00.11.4
Indifference point function log k1.42.53.4-1.8-1.8-1.7-1.71.7-1.6-1.8-1.7-1.8-1.00.11.4
Patch foraging total patch changes 0 sec0.81.56.71.40.91.21.5-1.5-0.10.4-0.1-0.1-1.7-2.6-0.5
Patch foraging total patch changes 12 sec1.31.62.51.61.31.41.5-1.51.31.41.41.20.5-0.4-1.2
Patch foraging total patch changes 18 sec0.30.40.91.00.40.80.7-0.70.40.40.50.2-0.4-0.9-0.5
Patch foraging total patch changes 24 sec1.11.93.01.61.51.71.7-1.71.21.41.21.10.0-1.2-1.2
Patch foraging total patch changes 6 sec1.72.64.82.11.51.92.2-2.20.91.51.10.9-0.8-2.1-1.3
Patch foraging time to switch 0 sec1.22.54.2-1.9-1.7-1.9-2.02.0-1.4-1.5-1.4-1.3-0.01.31.6
Patch foraging water rate 0 sec0.81.62.91.51.11.61.7-1.70.91.00.90.8-0.5-1.7-1.3
Patch foraging water rate 12 sec0.00.10.3-0.10.10.30.2-0.2-0.0-0.1-0.10.0-0.4-0.6-0.5
Patch foraging water rate 18 sec0.60.92.00.40.70.50.5-0.51.20.91.21.11.41.1-0.8
Patch foraging water rate 24 sec0.20.31.6-0.40.0-0.3-0.40.40.4-0.10.40.41.11.30.1
Patch foraging water rate 6 sec1.21.72.41.31.41.51.4-1.41.51.21.41.30.90.0-1.3
Seeking ratio, delayed vs. immediate footshock2.63.24.32.01.72.11.9-1.92.01.82.01.81.2-0.2-2.1
Distance traveled before self-admin4.76.110.02.93.13.23.0-3.02.32.52.02.40.8-1.2-2.1
Distance traveled after self-admin3.84.77.22.12.72.22.0-2.02.62.52.22.52.10.8-1.7
Extensor digitorum longus weight4.819.029.35.45.44.95.0-5.04.44.74.24.52.5-0.7-3.0
Bone: elastic displacement5.76.59.9-3.1-3.0-3.1-3.03.0-2.5-2.7-2.5-2.5-0.91.02.1
Bone: elastic work2.12.87.5-1.9-1.4-2.1-2.02.0-0.9-1.1-1.0-0.81.22.71.5
Bone: endosteal estimation0.92.13.92.01.62.01.7-1.71.41.41.11.10.1-1.2-1.0
Bone: endosteal perimeter0.91.83.51.81.61.91.6-1.61.11.20.91.1-0.2-1.3-0.9
Epididymis fat weight0.10.50.80.90.40.80.6-0.60.90.60.80.60.80.2-0.6
Delta time in closed arm before/after self-admin0.50.51.40.00.30.10.1-0.10.70.50.90.71.00.8-1.2
Delta time in open arm before/after self-admin0.20.20.7-0.0-0.0-0.10.0-0.0-0.5-0.3-0.6-0.4-0.7-0.60.8
Diff in mean of infusions in LGA sessions0.20.21.0-0.10.3-0.2-0.30.30.30.2-0.10.40.81.00.9
Delay discount exponential model param0.80.91.50.71.00.80.8-0.81.21.01.21.21.00.5-0.8
Extinction: sum of active levers before priming1.82.03.4-1.5-1.1-1.5-1.41.4-1.7-1.4-1.7-1.5-1.1-0.11.8
Active lever presses in extinction session 60.50.51.0-0.7-0.6-0.8-0.70.7-0.6-0.7-0.9-0.7-0.50.11.0
Bone: final force2.03.25.82.12.41.71.9-1.91.82.01.82.21.40.4-1.1
Bone: final moment1.72.84.91.82.21.51.7-1.71.71.91.72.11.60.7-1.0
Food consumed during 24 hour testing period0.71.01.91.41.01.21.2-1.20.90.81.00.80.0-0.8-0.8
Glucose1.22.03.81.91.31.71.5-1.51.61.31.61.30.6-0.5-1.2
Heart weight0.20.30.70.80.60.60.7-0.70.50.70.50.60.3-0.0-0.3
Delay discount hyperbolic model param0.60.71.20.51.00.60.7-0.71.10.91.01.10.90.5-0.7
Intermittent access intake day 1-15 change0.71.42.51.31.61.11.2-1.21.41.41.21.41.10.2-0.7
Intermittent access intake escalation0.71.52.81.21.71.01.2-1.21.41.51.21.51.30.5-0.7
Intermittent access intake escalation 22.83.25.11.52.11.31.4-1.42.12.12.12.22.31.2-1.1
Intermitt. access day 1 inactive lever presses0.10.61.41.20.51.01.0-1.00.60.60.80.3-0.2-0.8-0.4
Intermitt. access day 15 inactive lever presses0.20.41.60.61.30.60.8-0.80.30.70.30.70.1-0.3-0.2
Intermitt. access escalation Index0.10.20.40.60.50.50.5-0.50.40.40.40.40.2-0.2-0.0
Intermittent access day 1 total infusions1.11.83.0-1.3-1.1-1.5-1.31.3-1.5-1.4-1.7-1.4-1.6-0.41.0
Intermittent access day 15 total infusions0.30.41.60.41.30.20.4-0.40.70.80.21.00.60.5-0.1
Intermittent access terminal intake (last 3 days)1.01.33.91.22.01.01.1-1.11.21.40.81.50.80.2-0.3
Intermittent access total infusions0.30.41.40.71.20.50.6-0.60.50.70.20.80.1-0.1-0.1
Intermittent access day 1 locomotion1.62.03.2-1.5-1.4-1.6-1.41.4-1.5-1.5-1.8-1.5-1.5-0.41.0
Intermittent access day 15 total locomotion0.81.52.3-1.3-1.2-1.3-1.21.2-1.3-1.3-1.5-1.3-1.2-0.30.8
Intermittent access total locomotion0.70.91.7-1.3-0.8-1.3-1.11.1-0.8-0.8-1.1-0.8-0.30.60.7
Intermittent access standard deviation0.30.61.11.00.90.80.9-0.90.70.80.70.70.2-0.4-0.5
Left kidney weight0.52.24.31.81.41.92.0-2.01.11.10.90.7-0.7-2.1-1.3
Right kidney weight0.21.12.01.31.11.31.4-1.40.91.10.70.70.2-0.8-0.6
Cocaine induced anxiety0.10.10.30.30.00.50.4-0.40.30.20.60.10.2-0.3-0.5
Post-drug Anxiety1.01.12.11.40.91.51.3-1.30.90.91.20.70.1-0.9-1.0
Baseline Anxiety0.30.40.60.80.70.50.6-0.60.70.70.70.80.50.2-0.4
Tail length1.45.67.72.82.42.82.6-2.62.72.42.52.31.3-0.5-2.5
Length with tail1.04.67.92.72.02.82.6-2.62.01.91.71.5-0.1-2.0-2.2
Length without tail0.10.52.60.5-0.10.60.6-0.60.0-0.0-0.3-0.5-1.1-1.6-0.4
Times rat made contact with spout0.70.81.40.91.20.70.8-0.80.91.01.01.11.00.5-0.5
Lifetime Intake0.40.51.50.81.20.70.8-0.80.60.70.10.7-0.3-0.5-0.3
Liver weight, left0.10.10.40.00.20.10.2-0.2-0.5-0.0-0.5-0.2-0.6-0.70.3
Liver weight, right0.30.51.1-1.0-1.0-0.8-0.90.9-0.4-0.6-0.4-0.60.20.80.2
Locomotor activity0.00.00.10.2-0.00.10.0-0.00.10.10.1-0.10.20.30.3
Locomotor testing distance0.20.30.70.1-0.5-0.0-0.20.2-0.5-0.6-0.5-0.8-0.8-0.70.6
Locomotor testing rearing0.71.33.11.81.11.51.3-1.31.31.11.30.90.5-0.5-0.5
Locomotion in novel chamber0.20.30.5-0.6-0.7-0.7-0.60.6-0.4-0.3-0.1-0.40.20.60.3
Locomotion in novel chamber post-restriction1.32.24.31.31.41.11.2-1.21.61.81.71.82.11.3-1.0
Fecal boli incidents, locomotor time 11.21.72.6-1.4-1.6-1.4-1.41.4-1.4-1.3-1.3-1.4-0.70.21.4
Change in fecal boli incidents, locomotor task0.60.51.61.01.20.90.8-0.80.40.40.30.8-0.3-0.8-0.4
Time >=10cm from walls, locomotor time 10.20.20.70.40.80.30.4-0.4-0.20.2-0.60.0-0.7-0.70.5
Bouts of movement, locomotor time 10.80.93.6-0.7-0.2-1.1-0.90.9-1.2-0.9-1.0-0.8-0.20.31.9
Total resting periods, locomotor time 11.21.43.8-1.1-0.5-1.5-1.31.3-1.2-1.0-1.1-0.90.00.82.0
Rest time, locomotor task time 11.11.44.8-1.6-0.7-1.7-1.41.4-0.5-0.4-0.2-0.11.32.20.5
Distance moved, locomotor task time 11.32.03.81.81.41.91.8-1.80.90.90.70.9-0.7-1.8-1.1
Vertical activity count, locomotor time 10.61.54.41.51.01.61.6-1.60.30.50.10.4-1.1-2.1-1.0
Time >=10cm from walls, locomotor time 20.10.20.6-0.0-0.20.00.5-0.5-0.20.2-0.1-0.1-0.5-0.7-0.8
Bouts of movement, locomotor time 20.50.92.11.41.41.10.9-0.90.80.90.81.00.7-0.10.0
Total resting periods, locomotor time 20.30.51.31.11.10.80.6-0.60.50.60.50.80.60.10.4
Rest time, locomotor task time 20.40.50.9-1.00.1-0.9-0.80.8-0.5-0.3-0.7-0.10.41.00.7
Distance moved, locomotor task time 20.40.51.30.4-0.10.50.6-0.60.80.61.10.60.70.3-1.1
Vertical activity count, locomotor time 20.40.51.80.6-0.20.71.0-1.00.30.40.50.1-0.2-0.8-1.3
Light reinforcement 11.02.68.51.71.51.92.0-2.00.40.90.40.6-1.7-2.9-1.2
Light reinforcement 21.11.68.01.10.91.31.2-1.2-0.30.2-0.4-0.1-2.1-2.8-0.5
Bone: marrow area1.02.24.02.01.72.01.7-1.71.51.51.31.20.4-0.9-1.1
Bone: maximum diameter2.24.16.02.42.42.21.9-1.92.42.22.12.31.80.4-1.3
Bone: maximum force3.86.811.73.03.42.62.7-2.72.72.92.63.02.00.5-1.6
Bone: maximum moment3.25.69.72.73.12.32.4-2.42.52.72.42.82.10.7-1.4
Mean time between licks in bursts0.20.50.7-0.8-0.9-0.8-0.70.7-0.7-0.7-0.7-0.7-0.40.10.5
Mean num. licks in bursts1.82.84.4-2.1-1.8-2.1-1.81.8-1.8-1.8-1.7-1.7-1.00.31.2
Cd content in liver1.31.42.81.41.71.31.3-1.31.11.41.01.40.80.0-0.8
Co content in liver0.50.61.5-0.6-0.8-0.3-0.40.4-0.9-0.8-0.8-1.0-1.2-1.10.4
Cu content in liver1.01.22.1-1.4-1.3-1.4-1.21.2-1.1-1.0-1.2-1.1-0.40.50.8
Fe content in liver0.81.02.2-0.8-1.2-0.5-0.60.6-1.1-1.2-0.9-1.4-1.5-1.10.5
K content in liver0.40.40.9-0.6-0.5-0.2-0.20.2-0.8-0.5-0.8-0.7-0.9-0.90.2
Mg content in liver1.11.11.7-1.3-1.2-1.1-1.01.0-1.3-1.1-1.3-1.2-0.9-0.30.6
Mn content in liver1.92.13.61.21.91.31.3-1.31.61.71.21.81.71.0-0.9
Na content in liver0.70.71.3-1.1-0.9-1.0-1.11.1-0.8-0.8-0.8-0.8-0.20.30.8
Rb content in liver4.34.98.1-2.7-2.9-2.3-2.42.4-2.3-2.6-2.2-2.5-1.7-0.41.2
Se content in liver2.83.34.51.72.11.91.8-1.82.12.12.02.11.90.7-1.3
Sr content in liver0.40.41.70.51.30.50.7-0.70.00.8-0.00.80.40.30.0
Zn content in liver0.00.00.2-0.10.0-0.20.0-0.0-0.10.20.10.20.30.4-0.0
Bone: minimum diameter0.10.10.5-0.2-0.1-0.3-0.50.50.0-0.2-0.1-0.00.40.70.4
Time in familiar zone, hab. session 11.21.26.7-0.8-0.1-0.9-0.90.90.30.10.20.41.92.60.6
Time in novel zone, hab. session 12.72.77.5-1.0-1.6-0.8-0.80.8-1.9-1.7-1.9-2.0-2.7-2.40.7
Total zone transitions, hab. session 10.00.00.1-0.2-0.3-0.3-0.20.2-0.1-0.3-0.1-0.2-0.20.00.2
Total locomotion distance, hab. session 10.50.72.20.40.70.20.3-0.30.90.70.91.01.51.4-0.2
Locomotion velocity, hab. session 11.41.93.11.31.51.01.1-1.11.61.51.61.71.81.1-0.8
Time in familiar zone, hab. session 21.01.03.1-1.2-1.0-1.2-1.21.2-0.4-0.6-0.4-0.41.01.70.8
Time in novel zone, hab. session 21.31.34.1-0.7-0.6-0.4-0.50.5-1.2-1.1-1.4-1.3-2.0-1.70.6
Total zone transitions, hab. session 20.40.52.10.80.40.90.8-0.80.30.30.40.2-0.8-1.4-0.6
Total locomotion distance, hab. session 20.50.71.00.90.91.00.9-0.90.80.90.90.90.4-0.3-0.8
Locomotion velocity, hab. session 20.60.91.21.10.91.01.0-1.01.01.01.11.00.5-0.2-0.9
Novel to familiar place preference ratio3.23.55.7-1.9-1.9-1.6-1.61.6-2.2-2.1-2.4-2.1-2.2-1.31.3
Novelty place preference4.14.46.8-2.2-2.2-1.9-1.91.9-2.4-2.3-2.6-2.3-2.2-1.11.5
Time in novel zone, NPP test4.95.28.0-2.4-2.4-2.1-2.12.1-2.6-2.5-2.8-2.6-2.4-1.21.7
Total zone transitions, NPP test0.40.62.20.90.61.00.9-0.90.40.40.50.4-0.7-1.5-0.6
Total locomotion distance, NPP test1.21.62.41.51.41.51.5-1.51.01.21.01.2-0.2-1.3-1.2
Locomotion velocity, NPP test1.52.13.11.81.61.71.7-1.71.31.41.41.40.2-1.0-1.3
Intraocular pressure1.72.44.52.11.82.01.8-1.81.51.61.41.50.5-0.5-1.0
Delta distance traveled before/after self-admin0.10.10.40.00.1-0.0-0.00.00.40.20.50.30.60.6-0.1
Delta ambulatory time before/after self-admin0.10.20.5-0.5-0.3-0.5-0.50.50.0-0.20.1-0.20.40.70.4
Parametrial fat weight0.30.72.1-0.5-0.9-0.5-0.40.4-1.0-0.9-0.9-1.0-1.5-1.20.1
Pavlov. Cond. lever latency6.17.711.1-3.2-3.0-3.3-3.33.3-2.9-2.9-2.8-2.7-1.20.92.5
Pavlov. Cond. magazine entry latency0.20.30.50.70.30.70.6-0.60.60.50.70.40.2-0.2-0.5
Pavlov. Cond. change in total contacts2.32.44.01.81.42.01.9-1.91.61.51.61.30.3-0.9-1.5
Pavlov. Cond. index score2.63.24.72.11.72.22.0-2.02.01.92.01.71.0-0.4-1.6
Pavlov. Cond. latency score2.43.04.62.01.72.12.0-2.02.01.81.91.70.9-0.4-1.6
Pavlov. Cond. lever contacts5.66.79.73.02.73.13.0-3.02.82.72.72.51.2-0.7-2.3
Pavlov. Cond. magazine entry number0.30.40.9-0.7-0.4-0.8-0.70.7-0.9-0.7-0.9-0.6-0.5-0.10.5
Pavlov. Cond. intertrial magazine entries0.20.30.50.70.70.50.5-0.50.60.60.50.60.50.2-0.2
Pavlov. Cond. lever-magazine prob. diff.2.63.24.42.01.72.11.9-1.92.11.92.11.81.2-0.1-1.5
Pavlov. Cond. response bias3.03.75.42.31.92.32.2-2.22.12.02.11.80.9-0.5-1.7
Pavlov. Cond. lever latency2.63.65.4-1.8-1.9-1.6-1.61.6-2.2-2.1-2.3-2.2-2.3-1.41.3
Pavlov. Cond. magazine entry latency0.20.21.0-0.4-0.4-0.5-0.50.5-0.1-0.2-0.1-0.20.51.00.3
Pavlov. Cond. change in total contacts1.01.75.40.70.60.50.5-0.51.41.11.51.32.32.3-0.7
Pavlov. Cond. index score0.60.82.80.40.40.30.2-0.21.00.71.00.81.61.7-0.4
Pavlov. Cond. latency score0.81.03.30.50.60.40.3-0.31.20.91.11.01.81.8-0.4
Pavlov. Cond. lever contacts1.92.74.51.51.61.31.3-1.32.01.82.01.82.11.3-1.1
Pavlov. Cond. magazine entry number0.60.83.7-0.3-0.3-0.10.0-0.0-0.9-0.6-0.9-0.7-1.7-1.90.2
Pavlov. Cond. intertrial magazine entries0.10.20.30.60.40.60.5-0.50.40.50.30.3-0.0-0.5-0.3
Pavlov. Cond. lever-magazine prob. diff.0.60.83.30.40.40.20.2-0.21.00.71.00.81.71.8-0.3
Pavlov. Cond. response bias1.21.64.11.01.00.80.7-0.71.51.31.51.42.01.6-0.8
Time in closed arm before self-admin0.60.81.7-1.0-1.3-1.0-1.01.0-0.9-1.1-0.7-0.9-0.50.20.5
Time in closed arm after self-admin0.20.20.6-0.6-0.5-0.6-0.60.6-0.1-0.30.1-0.10.50.8-0.1
Time in open arm before self-admin0.91.01.71.31.21.31.3-1.30.60.90.30.7-0.3-1.2-0.6
Time in open arm after self-admin0.90.91.81.31.41.31.3-1.30.60.90.40.6-0.2-1.0-0.1
Bone: periosteal estimation1.73.65.72.42.32.21.9-1.92.22.01.92.01.3-0.0-1.2
Bone: periosteal perimeter0.50.91.81.31.21.31.1-1.10.90.90.70.80.1-0.9-0.5
Bone: post-yield work2.23.25.42.32.32.12.2-2.21.61.81.41.80.3-1.2-1.3
Progressive ratio test 1 active lever presses0.10.10.60.20.30.00.2-0.2-0.00.0-0.4-0.1-0.8-0.60.1
Progressive ratio test 1 breakpoint0.10.10.50.30.40.10.3-0.30.10.1-0.3-0.0-0.7-0.70.0
Progressive ratio test 1 inactive lever presses0.91.22.11.41.41.41.5-1.50.70.90.50.6-0.7-1.5-0.5
Progressive ratio test 2 active lever presses0.20.21.0-0.00.20.00.0-0.0-0.2-0.2-0.7-0.3-1.0-0.80.3
Progressive ratio test 2 breakpoint0.20.21.2-0.10.1-0.0-0.00.0-0.3-0.2-0.8-0.4-1.1-0.80.3
Progressive ratio test 2 inactive lever presses0.30.51.41.01.20.80.8-0.80.60.80.40.70.2-0.30.1
Incentive Sensitization - Responses0.10.10.30.40.50.60.4-0.40.30.20.10.2-0.3-0.5-0.2
Incentive Sensitization - Breakpoint0.10.10.30.20.30.40.3-0.30.20.10.00.0-0.4-0.5-0.1
Sum of active levers in priming session hrs 5-64.23.95.7-1.7-2.0-1.6-1.51.5-2.3-2.2-2.4-2.4-2.4-1.31.9
Progressive ratio0.20.30.7-0.4-0.9-0.3-0.40.4-0.5-0.6-0.2-0.6-0.7-0.6-0.1
Food seeking constrained by brief footshock6.78.213.83.62.83.63.7-3.72.62.62.72.20.3-1.9-2.8
Seeking ratio, punishment vs. effort2.94.26.72.32.62.32.5-2.52.12.11.82.01.1-0.3-1.6
Retroperitoneal fat weight0.62.45.1-1.7-2.2-1.8-1.91.9-1.1-1.6-1.1-1.5-0.31.01.0
Reaction time number correct0.10.10.50.1-0.60.1-0.00.0-0.3-0.4-0.1-0.5-0.7-0.70.1
Reaction time mean minus median0.82.08.00.51.4-0.3-0.20.21.21.11.11.62.62.80.7
Reaction time mean minus median AUC0.92.46.51.12.00.50.5-0.51.71.51.52.02.62.30.2
Reaction time num false alarms0.40.51.60.40.80.20.2-0.20.70.80.50.71.21.20.5
Reaction time num false alarms AUC0.61.02.11.21.40.90.9-0.91.01.20.91.01.00.50.2
Reaction time trials correct on left0.10.10.50.1-0.60.1-0.00.0-0.3-0.4-0.1-0.5-0.7-0.70.1
Reaction time trials on left0.10.20.50.0-0.60.0-0.10.1-0.4-0.4-0.2-0.5-0.7-0.60.2
Reaction time mean1.11.85.0-1.4-0.8-1.8-1.71.7-0.6-0.8-0.6-0.41.12.21.5
Reaction time mean AUC1.32.05.9-1.5-0.8-1.8-1.81.8-0.6-0.8-0.6-0.41.32.41.5
Median of all reaction times2.02.84.8-2.0-1.7-2.2-2.22.2-1.4-1.6-1.4-1.30.11.41.6
Reaction time omissions1.52.23.9-1.3-0.8-1.8-1.61.6-1.8-1.4-1.9-1.3-0.80.12.0
Reaction time false alarm rate0.30.51.20.41.00.10.3-0.30.60.80.40.71.11.00.5
Reaction time premature initiation rate2.02.74.4-2.0-2.0-2.1-2.02.0-1.3-1.7-1.5-1.5-0.11.31.3
Reaction time premature initiations1.42.54.7-1.7-2.2-1.9-1.81.8-1.4-1.7-1.4-1.7-0.40.81.2
Std. dev. reaction times0.81.47.4-0.30.4-1.0-1.01.00.40.30.30.82.12.71.2
Reaction time trials completed0.10.20.50.0-0.60.0-0.10.1-0.4-0.4-0.2-0.5-0.7-0.60.2
Reaction time trials AUC0.10.20.5-0.0-0.7-0.0-0.20.2-0.4-0.5-0.3-0.6-0.7-0.60.2
Run reversals in cocaine runway, females0.30.31.3-0.5-0.4-0.7-0.80.8-0.1-0.20.0-0.00.51.10.7
Run reversals in cocaine runway, males0.10.10.3-0.3-0.2-0.3-0.50.5-0.1-0.0-0.2-0.10.00.20.2
Latency to leave start box in cocaine runway0.80.91.50.90.81.01.0-1.01.01.10.80.90.80.1-1.2
Latency to leave start box in cocaine runway, F0.20.30.7-0.3-0.5-0.1-0.20.2-0.6-0.4-0.8-0.6-0.8-0.80.0
Latency to leave start box in cocaine runway, M3.93.75.11.92.12.12.3-2.32.02.01.71.91.30.0-2.3
Std. dev. time between licks in bursts0.20.30.4-0.6-0.6-0.6-0.70.7-0.5-0.5-0.5-0.5-0.00.40.5
Total sessions with >9 infusions0.50.61.31.01.10.91.0-1.00.90.80.20.6-0.3-0.7-0.6
Short access day 1 total inactive lever presses1.11.52.71.61.21.51.7-1.70.60.90.60.6-0.7-1.6-0.8
Short access day 10 total inactive lever presses0.51.21.91.41.31.11.3-1.30.71.21.31.00.7-0.4-0.6
Short access day 1 total infusions0.71.01.61.21.31.21.3-1.30.70.80.20.6-0.6-1.2-0.5
Short access day 10 total infusions0.20.31.40.2-0.0-0.00.1-0.1-0.4-0.3-0.6-0.4-1.2-1.00.0
Short access total infusions0.30.31.10.60.60.50.6-0.60.20.2-0.40.0-1.0-1.0-0.2
Short access day 1 locomotion1.41.72.6-1.1-1.4-1.2-1.21.2-1.5-1.5-1.6-1.5-1.4-0.51.2
Short access day 10 total locomotion0.71.32.6-1.4-1.5-1.6-1.51.5-0.6-1.0-0.7-0.90.11.20.6
Short access total locomotion0.60.71.1-0.7-0.9-1.0-0.90.9-0.8-0.9-1.0-0.9-0.9-0.10.6
One hour access (0.3 mA shock)0.30.30.70.60.80.60.7-0.70.50.6-0.10.4-0.3-0.6-0.1
Compulsive drug intake0.10.10.3-0.1-0.6-0.1-0.30.30.2-0.10.2-0.10.30.5-0.0
One hour access (shock baseline)0.30.52.00.60.90.60.7-0.70.00.2-0.40.1-1.0-1.4-0.2
Social response proportion2.52.94.3-1.9-2.0-2.1-2.12.1-1.7-1.9-1.7-1.5-0.80.51.5
Social responses0.30.40.80.90.80.80.7-0.70.70.60.70.80.3-0.2-0.5
Social time0.10.10.6-0.0-0.3-0.0-0.10.1-0.4-0.3-0.3-0.3-0.7-0.80.4
Soleus weight0.51.57.50.4-0.30.30.3-0.3-1.1-0.8-0.9-1.1-2.4-2.70.2
Bone: stiffness4.98.012.73.33.62.93.0-3.03.03.12.93.22.20.4-1.9
Tibialis anterior weight6.923.337.96.25.55.85.7-5.74.85.04.74.72.2-1.6-3.8
Time to tail flick, vehicle, before self-admin1.11.22.3-1.5-1.5-1.4-1.31.3-1.0-1.2-0.8-1.1-0.40.30.1
Time to tail flick, vehicle, after self-admin0.10.10.4-0.1-0.10.1-0.10.10.40.10.30.30.50.5-0.6
Time to tail flick, test, before self-admin0.50.61.40.60.70.80.7-0.70.70.70.90.80.50.0-1.2
Time to tail flick, test, after self-admin0.90.92.30.80.40.30.4-0.41.10.91.31.11.51.3-0.8
Delta time to tail flick, vehicle, before/after SA0.40.40.80.90.70.80.6-0.60.70.70.70.70.4-0.1-0.2
Delta time to tail flick, test, before/after SA0.30.30.7-0.5-0.6-0.7-0.60.6-0.2-0.3-0.1-0.20.40.90.5
Tibia length0.20.52.50.50.50.90.7-0.7-0.10.0-0.4-0.0-1.1-1.6-0.6
Ambulatory time before self-admin3.04.57.92.72.72.82.6-2.61.82.11.62.00.4-1.2-1.5
Ambulatory time after self-admin1.61.93.71.51.91.71.6-1.61.51.51.11.40.7-0.3-0.9
Bone: tissue strength0.20.20.40.50.60.30.6-0.60.30.60.40.50.30.0-0.3
Total heroin consumption0.91.12.3-0.9-0.8-0.7-0.70.7-1.1-1.0-1.5-1.3-1.4-0.81.1
Bone: trabecular number0.91.52.31.31.40.81.0-1.01.41.31.51.41.41.0-0.6
Bone: trabecular spacing0.10.10.40.20.30.20.1-0.10.40.40.20.40.60.50.0
Bone: trabecular thickness0.20.30.6-0.7-0.6-0.6-0.60.6-0.2-0.5-0.4-0.40.20.80.3
Bone: trabecular tissue density3.45.06.92.52.62.62.4-2.42.42.52.22.41.6-0.1-1.7
Water consumed over 24 hours1.21.62.61.51.61.31.4-1.41.31.31.31.40.80.0-0.9
Number of responses in last shaping day1.31.45.90.3-0.40.40.5-0.5-0.9-0.6-1.4-1.1-2.3-2.4-0.1