Hub : Genes

Dcaf12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Dcaf12 0.19 0.11 9.0e-10 0.08 0.08 0.11 0.11 3.6e-08 4.3e-08 1.5e-10 2.8e-10
2 PL gene expression Dcaf12 0.05 0.04 8.4e-04 0.02 0.03 0.03 0.03 1.3e-03 4.0e-04 2.0e-04 2.5e-04
3 NAcc intron excision ratio chr5_61259133_61261619 0.02 0.02 9.4e-03 0.01 0 0.01 0.01 1.1e-02 1.3e-01 2.6e-02 1.4e-02
4 Adipose alternative polyA NM_001427703.1 0.04 0.03 1.8e-03 0.02 0.01 0.02 0.02 2.2e-03 7.6e-03 5.2e-03 3.6e-03
5 Adipose alternative polyA XM_063288402.1 0.04 0.03 1.9e-03 0.02 0.01 0.02 0.02 2.4e-03 7.1e-03 5.0e-03 2.9e-03
6 NAcc gene expression Dcaf12 0.04 0.03 1.5e-04 0.03 0.01 0.02 0 1.3e-05 1.9e-03 2.8e-04 6.8e-02
7 IC gene expression Dcaf12 0.17 0.12 2.4e-03 0.02 0.02 0 0.02 3.9e-02 3.4e-02 2.7e-01 3.3e-02
8 IL gene expression Dcaf12 0.21 0.14 2.5e-03 0.11 0.1 0.08 0.05 1.5e-03 2.8e-03 5.9e-03 2.1e-02
9 BLA gene expression Dcaf12 0.17 0.1 1.3e-05 0.11 0.09 0.08 0.11 2.8e-06 1.1e-05 5.4e-05 1.8e-06
10 Liver mRNA stability Dcaf12 0.04 0.03 5.2e-05 0.01 0.04 0.04 0.03 7.4e-03 8.3e-05 7.0e-05 1.1e-04
11 NAcc mRNA stability Dcaf12 0.02 0.01 2.6e-03 0.02 0.01 0.01 0.01 8.0e-04 3.5e-03 1.3e-02 6.8e-03
12 RMTg isoform ratio XM_063288402.1 0.29 0.16 8.9e-05 0.15 0.08 0.17 0.14 8.5e-05 3.9e-03 3.4e-05 1.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.01.92.8-1.5-1.6-1.0-1.21.2-1.51.5-1.71.6-1.6-1.10.7
Area under the delay curve0.61.01.60.71.10.80.9-0.91.3-1.01.2-1.31.10.5-1.0
BMI with tail1.03.65.8-2.4-1.8-1.9-2.02.0-2.02.2-2.21.9-1.7-0.51.1
BMI without tail0.84.26.9-2.6-2.0-2.2-2.22.2-2.32.2-2.32.1-1.6-0.21.5
Body weight2.29.416.2-4.0-3.1-3.7-3.73.7-3.23.2-3.02.7-1.31.22.7
Weight adjusted by age0.10.31.5-0.4-0.2-0.6-0.60.60.10.10.3-0.20.81.20.4
Bone surface0.51.02.0-1.4-1.2-1.1-1.01.0-1.11.0-1.11.0-0.7-0.00.6
Bone volume0.51.01.6-1.2-1.2-0.9-0.90.9-1.11.1-1.11.1-1.0-0.50.5
Breakpoint value in progressive ratio session1.42.57.80.50.90.50.4-0.41.9-1.42.2-1.82.82.3-1.4
Number of licking bursts2.26.69.2-3.0-3.0-2.8-2.62.6-2.82.9-2.82.8-2.1-0.31.7
Context. condit. distance diff. score0.10.10.30.40.40.40.5-0.50.2-0.30.1-0.2-0.1-0.4-0.3
Locomotion velocity, session 11.71.911.7-0.7-0.0-0.9-0.80.80.6-0.40.4-0.72.73.40.4
Locomotion distance, session 10.50.63.7-0.50.0-0.6-0.50.50.2-0.20.1-0.41.41.90.3
Locomotion velocity, session 21.51.92.7-1.5-1.4-1.3-1.31.3-1.61.5-1.61.6-1.3-0.61.0
Locomotion distance, session 21.41.93.5-1.9-1.3-1.8-1.71.7-1.21.2-1.31.00.11.41.2
Locomotion velocity, session 30.30.42.1-0.4-0.3-0.4-0.50.50.3-0.10.1-0.11.11.50.3
Locomotion distance, session 31.31.42.5-1.6-1.2-1.5-1.51.5-1.01.1-1.00.90.11.11.2
Stereotopy head waving bouts, day 30.30.41.7-0.3-1.0-0.5-0.50.50.20.10.60.10.81.30.2
Stereotopy head waving duration, day 30.10.21.0-0.1-1.0-0.2-0.20.20.10.20.50.30.20.5-0.2
Locomotion velocity, session 70.00.00.10.20.10.30.2-0.20.3-0.20.3-0.10.2-0.0-0.3
Locomotion distance, session 70.10.20.4-0.6-0.3-0.4-0.50.5-0.00.3-0.20.20.30.60.3
Stereotopy head waving bouts, day 71.61.93.6-1.5-1.9-1.6-1.61.6-1.51.4-1.11.4-0.50.51.3
Stereotopy head waving duration, day 71.11.43.1-1.2-1.8-1.3-1.31.3-1.31.3-0.91.3-0.60.31.0
Locomotion velocity, session 80.30.32.0-0.3-0.1-0.4-0.30.30.3-0.30.1-0.31.21.40.1
Locomotion distance, session 80.20.31.5-0.5-0.1-0.6-0.40.4-0.00.0-0.2-0.10.81.20.3
Degree of sensitization distance0.60.61.01.00.71.00.9-0.90.9-0.80.9-0.70.2-0.4-0.8
Degree of sensitization stereotypy1.51.72.5-1.4-1.6-1.4-1.41.4-1.51.4-1.31.4-0.8-0.01.2
Conditioned locomotion0.20.31.7-0.20.1-0.3-0.20.20.3-0.30.4-0.40.91.30.2
Cocaine response after cond. corrected1.21.94.61.11.00.90.8-0.81.8-1.31.8-1.42.11.7-0.7
Cocaine response after cond. not corrected1.21.75.01.00.80.70.6-0.61.6-1.21.7-1.32.22.0-0.6
Cocaine response before conditioning0.70.81.5-1.0-1.0-0.9-0.90.9-1.20.9-1.11.0-0.8-0.10.6
Saline control response1.21.72.8-1.5-1.7-1.6-1.71.7-1.01.1-0.81.00.21.31.1
Bone: connectivity density0.50.81.6-0.9-0.9-0.4-0.50.5-1.00.8-1.11.0-1.3-1.20.3
Bone: cortical apparent density0.20.42.00.10.00.10.2-0.2-0.60.2-0.60.4-1.2-1.40.1
Bone: cortical area2.64.25.9-2.2-2.4-1.9-1.71.7-2.42.3-2.22.4-2.4-1.21.1
Bone: cortical porosity0.10.10.20.50.20.50.4-0.40.3-0.20.4-0.2-0.1-0.4-0.3
Bone: cortical porosity0.00.00.1-0.1-0.3-0.1-0.20.2-0.10.20.00.2-0.1-0.00.1
Bone: cortical thickness1.32.25.7-1.1-1.4-0.9-0.80.8-1.81.6-1.61.8-2.4-1.90.6
Bone: cortical thickness0.30.31.80.50.30.50.6-0.6-0.0-0.20.2-0.0-0.9-1.3-0.5
Bone: cortical tissue density0.20.31.60.20.10.20.3-0.3-0.50.1-0.50.3-1.1-1.30.1
Condit. Reinf. active minus inactive responses0.40.50.7-0.7-0.6-0.8-0.80.8-0.90.7-0.80.7-0.5-0.00.7
Condit. Reinf. active-inactive response ratio0.50.60.90.90.90.90.9-0.90.7-0.80.6-0.70.2-0.3-0.7
Condit. Reinf. active responses2.32.93.9-2.0-1.8-1.9-1.91.9-2.01.8-1.91.8-1.2-0.11.4
Condit. Reinf. inactive responses2.63.44.6-2.1-2.0-1.9-1.91.9-2.12.0-2.02.0-1.6-0.51.4
Incentive salience index mean3.34.26.2-2.5-2.1-2.5-2.42.4-2.22.2-2.22.0-1.00.61.7
Condit. Reinf. lever presses7.411.217.4-4.2-3.5-4.1-4.04.0-3.43.4-3.53.1-1.11.62.8
Condit. Reinf. active minus inactive responses0.40.61.1-0.8-0.6-0.7-0.70.7-0.90.8-1.10.9-0.8-0.40.6
Condit. Reinf. active-inactive response ratio0.10.10.50.00.20.20.2-0.2-0.20.0-0.30.2-0.5-0.7-0.0
Condit. Reinf. active responses1.52.13.4-1.8-1.3-1.6-1.51.5-1.71.5-1.81.5-1.3-0.21.2
Condit. Reinf. inactive responses2.53.75.6-2.2-1.8-2.0-1.81.8-2.42.1-2.32.0-2.0-0.71.5
Condit. Reinf. lever presses2.74.05.7-1.9-1.9-1.6-1.81.8-2.42.2-2.32.2-2.4-1.51.6
Condit. Reinf. lever reinforcers received1.92.63.9-2.0-1.5-1.7-1.71.7-1.91.7-2.01.7-1.3-0.21.4
Conditioned reinforcement - actives0.20.61.4-0.9-1.2-0.7-0.70.7-1.11.0-0.40.9-0.5-0.40.1
Conditioned reinforcement - inactives0.10.20.9-0.5-0.9-0.3-0.50.5-0.40.6-0.20.3-0.00.1-0.4
Conditioned locomotion0.10.20.7-0.6-0.9-0.4-0.50.5-0.30.60.30.50.10.20.2
Patch foraging indifference point 0 sec0.51.47.7-1.0-0.4-0.8-1.11.10.6-0.10.5-0.62.12.80.1
Patch foraging indifference point AUC2.76.49.1-3.0-2.6-2.9-2.92.9-2.62.7-2.72.5-1.20.82.4
Delay disc. indifference point, 0s delay1.01.21.80.81.10.81.0-1.01.1-1.11.3-1.31.10.6-1.4
Delay disc. indifference point, 16s delay1.01.53.30.50.80.90.6-0.61.6-1.31.5-1.51.81.3-1.3
Delay disc. indifference point, 2s delay0.30.30.8-0.4-0.7-0.3-0.20.2-0.50.6-0.50.6-0.9-0.7-0.0
Delay disc. indifference point, 24s delay0.30.41.10.51.00.80.6-0.60.8-0.70.5-0.80.40.0-0.6
Delay disc. indifference point, 4s delay0.20.20.50.50.70.50.5-0.50.6-0.40.7-0.60.3-0.1-0.1
Delay disc. indifference point, 8s delay0.00.10.20.00.40.10.3-0.30.4-0.20.2-0.40.1-0.0-0.3
Indifference point function ln k0.82.53.41.81.81.71.7-1.71.6-1.81.7-1.81.0-0.1-1.3
Indifference point function log k0.82.53.41.81.81.71.7-1.71.6-1.81.7-1.81.0-0.1-1.3
Patch foraging total patch changes 0 sec0.51.56.7-1.4-0.9-1.2-1.51.50.10.40.1-0.11.72.60.5
Patch foraging total patch changes 12 sec1.21.62.5-1.6-1.3-1.4-1.51.5-1.31.4-1.41.2-0.50.41.2
Patch foraging total patch changes 18 sec0.20.40.9-1.0-0.4-0.8-0.70.7-0.40.4-0.50.20.40.90.5
Patch foraging total patch changes 24 sec0.61.93.0-1.6-1.5-1.7-1.71.7-1.21.4-1.21.1-0.01.21.2
Patch foraging total patch changes 6 sec1.62.64.8-2.1-1.5-1.9-2.22.2-0.91.4-1.10.90.82.11.2
Patch foraging time to switch 0 sec0.72.54.21.91.71.92.0-2.01.4-1.51.4-1.30.0-1.3-1.5
Patch foraging water rate 0 sec0.41.62.9-1.5-1.1-1.6-1.71.7-0.91.0-0.90.80.51.71.3
Patch foraging water rate 12 sec0.00.10.30.1-0.1-0.3-0.20.20.0-0.10.10.00.40.60.5
Patch foraging water rate 18 sec0.40.92.0-0.4-0.7-0.5-0.50.5-1.20.9-1.21.1-1.4-1.10.8
Patch foraging water rate 24 sec0.20.31.60.4-0.00.30.4-0.4-0.4-0.1-0.40.4-1.1-1.3-0.1
Patch foraging water rate 6 sec1.11.72.4-1.3-1.4-1.5-1.41.4-1.51.2-1.41.3-0.9-0.01.3
Seeking ratio, delayed vs. immediate footshock2.33.24.3-2.0-1.7-2.1-1.91.9-2.01.8-2.01.8-1.20.22.1
Distance traveled before self-admin2.86.110.0-2.9-3.1-3.2-3.03.0-2.32.5-2.02.4-0.81.22.1
Distance traveled after self-admin2.74.77.2-2.1-2.7-2.2-2.02.0-2.62.5-2.22.5-2.1-0.81.7
Extensor digitorum longus weight4.819.029.3-5.4-5.4-4.9-5.05.0-4.44.7-4.24.5-2.50.73.0
Bone: elastic displacement5.26.59.93.13.03.13.0-3.02.5-2.72.5-2.50.9-1.0-2.1
Bone: elastic work2.12.77.51.91.42.12.0-2.00.9-1.11.0-0.8-1.2-2.7-1.5
Bone: endosteal estimation0.82.13.9-2.0-1.6-2.0-1.71.7-1.41.4-1.11.1-0.11.21.0
Bone: endosteal perimeter0.71.83.5-1.8-1.6-1.9-1.61.6-1.11.2-0.91.10.11.30.9
Epididymis fat weight0.10.50.8-0.9-0.4-0.8-0.60.6-0.90.6-0.80.6-0.8-0.20.5
Delta time in closed arm before/after self-admin0.50.51.4-0.0-0.3-0.1-0.10.1-0.70.5-0.90.7-1.0-0.81.2
Delta time in open arm before/after self-admin0.20.20.70.00.00.1-0.00.00.5-0.30.6-0.40.70.6-0.8
Diff in mean of infusions in LGA sessions0.10.21.00.1-0.30.20.3-0.3-0.30.20.10.4-0.8-1.0-0.9
Delay discount exponential model param0.60.91.5-0.7-1.0-0.8-0.80.8-1.21.0-1.21.2-1.0-0.50.8
Extinction: sum of active levers before priming1.32.03.41.51.11.51.4-1.41.7-1.41.7-1.51.10.1-1.8
Active lever presses in extinction session 60.50.51.00.70.60.80.7-0.70.6-0.70.9-0.70.5-0.1-1.0
Bone: final force2.03.25.8-2.1-2.4-1.7-1.91.9-1.82.0-1.82.2-1.4-0.41.1
Bone: final moment1.72.84.9-1.8-2.2-1.5-1.71.7-1.71.9-1.72.1-1.6-0.70.9
Food consumed during 24 hour testing period0.50.91.9-1.4-1.0-1.2-1.21.2-0.90.8-1.00.8-0.00.80.8
Glucose1.21.93.8-1.9-1.3-1.7-1.51.5-1.61.3-1.61.3-0.60.51.2
Heart weight0.20.30.7-0.8-0.6-0.6-0.70.7-0.50.7-0.50.6-0.30.00.3
Delay discount hyperbolic model param0.50.71.2-0.5-1.0-0.6-0.70.7-1.10.9-1.01.1-0.9-0.50.7
Intermittent access intake day 1-15 change0.31.42.5-1.3-1.6-1.1-1.21.2-1.41.4-1.21.4-1.1-0.20.7
Intermittent access intake escalation0.31.52.8-1.2-1.7-1.0-1.21.2-1.41.5-1.21.5-1.3-0.50.7
Intermittent access intake escalation 21.93.25.1-1.5-2.1-1.3-1.41.4-2.12.1-2.12.2-2.3-1.21.1
Intermitt. access day 1 inactive lever presses0.00.61.4-1.2-0.5-1.0-1.01.0-0.60.6-0.80.30.20.80.4
Intermitt. access day 15 inactive lever presses0.10.41.6-0.6-1.3-0.6-0.80.8-0.30.7-0.30.7-0.10.30.2
Intermitt. access escalation Index0.10.20.4-0.6-0.5-0.5-0.50.5-0.40.4-0.40.4-0.20.20.0
Intermittent access day 1 total infusions0.61.83.01.31.11.51.3-1.31.5-1.41.7-1.41.60.4-1.0
Intermittent access day 15 total infusions0.20.41.6-0.4-1.3-0.2-0.40.4-0.70.8-0.21.0-0.6-0.50.1
Intermittent access terminal intake (last 3 days)0.71.33.9-1.2-2.0-1.0-1.11.1-1.21.4-0.81.5-0.8-0.20.3
Intermittent access total infusions0.30.41.4-0.7-1.2-0.5-0.60.6-0.50.7-0.20.8-0.10.10.1
Intermittent access day 1 locomotion1.12.03.21.51.41.61.4-1.41.5-1.51.8-1.51.50.4-0.9
Intermittent access day 15 total locomotion0.41.52.31.31.21.31.2-1.21.3-1.31.5-1.31.20.3-0.8
Intermittent access total locomotion0.70.91.71.30.81.31.1-1.10.8-0.81.1-0.80.3-0.6-0.6
Intermittent access standard deviation0.10.61.1-1.0-0.9-0.8-0.90.9-0.70.8-0.70.7-0.20.40.5
Left kidney weight0.32.24.3-1.8-1.4-1.9-2.02.0-1.11.1-0.90.70.72.11.3
Right kidney weight0.21.12.0-1.3-1.1-1.3-1.41.4-0.91.1-0.70.7-0.20.80.7
Cocaine induced anxiety0.00.10.3-0.3-0.0-0.5-0.40.4-0.30.2-0.60.1-0.20.30.5
Post-drug Anxiety1.01.12.1-1.4-0.9-1.5-1.31.3-0.90.9-1.20.7-0.10.91.0
Baseline Anxiety0.20.40.6-0.8-0.7-0.5-0.60.6-0.70.7-0.70.8-0.5-0.20.4
Tail length1.05.67.7-2.8-2.4-2.8-2.62.6-2.72.4-2.52.3-1.30.52.5
Length with tail1.04.67.9-2.7-2.0-2.8-2.62.6-2.01.9-1.71.50.12.02.2
Length without tail0.10.52.6-0.50.1-0.6-0.60.6-0.0-0.00.3-0.51.11.60.4
Times rat made contact with spout0.70.81.4-0.9-1.2-0.7-0.80.8-0.91.0-1.01.1-1.0-0.50.5
Lifetime Intake0.40.51.5-0.8-1.2-0.7-0.80.8-0.60.7-0.10.70.30.50.3
Liver weight, left0.10.10.4-0.0-0.2-0.1-0.20.20.5-0.00.5-0.20.60.7-0.3
Liver weight, right0.30.51.11.01.00.80.9-0.90.4-0.60.4-0.6-0.2-0.8-0.1
Locomotor activity0.00.00.1-0.20.0-0.1-0.00.0-0.10.1-0.1-0.1-0.2-0.3-0.3
Locomotor testing distance0.10.30.7-0.10.50.00.2-0.20.5-0.60.5-0.80.80.7-0.6
Locomotor testing rearing0.41.33.1-1.8-1.1-1.5-1.31.3-1.31.1-1.30.9-0.50.50.4
Locomotion in novel chamber0.20.30.50.60.70.70.6-0.60.4-0.30.1-0.4-0.2-0.6-0.3
Locomotion in novel chamber post-restriction0.72.24.3-1.3-1.4-1.1-1.21.2-1.61.8-1.71.8-2.1-1.31.0
Fecal boli incidents, locomotor time 10.61.72.61.41.61.41.4-1.41.4-1.31.3-1.40.7-0.2-1.4
Change in fecal boli incidents, locomotor task0.50.51.6-1.0-1.2-0.9-0.80.8-0.40.4-0.30.80.30.80.4
Time >=10cm from walls, locomotor time 10.20.20.7-0.4-0.8-0.3-0.40.40.20.20.60.00.70.7-0.5
Bouts of movement, locomotor time 10.70.93.60.70.21.10.9-0.91.2-0.91.0-0.80.2-0.3-1.9
Total resting periods, locomotor time 11.21.43.71.10.51.51.3-1.31.2-1.01.1-0.9-0.0-0.8-1.9
Rest time, locomotor task time 10.91.44.81.60.71.71.4-1.40.5-0.30.2-0.1-1.3-2.2-0.5
Distance moved, locomotor task time 10.72.03.8-1.8-1.4-1.9-1.81.8-0.90.9-0.70.90.71.81.1
Vertical activity count, locomotor time 10.21.54.4-1.5-1.0-1.6-1.61.6-0.30.5-0.10.41.12.10.9
Time >=10cm from walls, locomotor time 20.10.20.60.00.2-0.0-0.50.50.20.20.1-0.10.50.70.7
Bouts of movement, locomotor time 20.30.92.1-1.4-1.4-1.1-0.90.9-0.80.9-0.81.0-0.70.1-0.0
Total resting periods, locomotor time 20.10.51.3-1.1-1.1-0.8-0.60.6-0.50.6-0.50.8-0.6-0.1-0.4
Rest time, locomotor task time 20.30.50.91.0-0.10.90.8-0.80.5-0.30.7-0.1-0.4-1.0-0.6
Distance moved, locomotor task time 20.30.51.2-0.40.1-0.5-0.60.6-0.80.6-1.10.6-0.7-0.31.1
Vertical activity count, locomotor time 20.20.51.7-0.60.2-0.7-1.01.0-0.30.4-0.50.10.20.81.3
Light reinforcement 10.62.68.5-1.7-1.5-1.9-2.02.0-0.40.9-0.40.61.72.91.1
Light reinforcement 20.71.68.0-1.1-0.9-1.3-1.21.20.30.20.4-0.12.12.80.5
Bone: marrow area0.92.24.0-2.0-1.7-2.0-1.71.7-1.51.5-1.31.2-0.40.91.1
Bone: maximum diameter2.14.16.0-2.4-2.4-2.2-1.91.9-2.42.2-2.12.3-1.8-0.41.3
Bone: maximum force3.46.711.7-3.0-3.4-2.6-2.72.7-2.72.9-2.63.0-2.0-0.51.6
Bone: maximum moment3.05.69.7-2.7-3.1-2.3-2.42.4-2.52.7-2.42.8-2.1-0.71.4
Mean time between licks in bursts0.10.50.70.80.90.80.7-0.70.7-0.70.7-0.70.4-0.1-0.5
Mean num. licks in bursts1.02.84.42.11.82.11.8-1.81.8-1.81.7-1.71.0-0.3-1.2
Cd content in liver1.31.42.8-1.4-1.7-1.3-1.31.3-1.11.4-1.01.4-0.8-0.00.8
Co content in liver0.50.61.50.60.80.30.4-0.40.9-0.80.8-1.01.21.1-0.4
Cu content in liver1.01.22.11.41.31.41.2-1.21.1-1.01.2-1.10.4-0.5-0.7
Fe content in liver0.81.02.20.81.20.50.6-0.61.1-1.20.9-1.41.51.1-0.5
K content in liver0.40.40.90.60.50.20.2-0.20.8-0.60.8-0.70.90.9-0.2
Mg content in liver1.01.11.71.31.21.11.0-1.01.3-1.11.3-1.20.90.3-0.6
Mn content in liver1.92.13.6-1.2-1.9-1.3-1.31.3-1.61.7-1.21.8-1.7-1.00.9
Na content in liver0.70.71.31.10.91.01.1-1.10.8-0.80.8-0.80.2-0.3-0.7
Rb content in liver4.24.98.12.72.92.32.4-2.42.3-2.62.2-2.51.70.4-1.2
Se content in liver2.83.34.5-1.7-2.1-1.9-1.81.8-2.12.1-2.02.1-1.9-0.71.3
Sr content in liver0.40.41.7-0.5-1.3-0.5-0.70.7-0.00.80.00.8-0.4-0.3-0.0
Zn content in liver0.00.00.20.1-0.00.2-0.00.00.10.2-0.10.2-0.3-0.40.0
Bone: minimum diameter0.10.10.50.20.10.30.5-0.5-0.0-0.20.1-0.0-0.4-0.7-0.4
Time in familiar zone, hab. session 11.11.26.70.80.10.90.9-0.9-0.30.1-0.20.4-1.9-2.6-0.6
Time in novel zone, hab. session 12.52.77.51.01.60.80.8-0.81.9-1.71.9-2.02.72.4-0.7
Total zone transitions, hab. session 10.00.00.10.20.30.30.2-0.20.1-0.30.1-0.20.2-0.0-0.2
Total locomotion distance, hab. session 10.50.72.2-0.4-0.7-0.2-0.30.3-0.90.7-0.91.0-1.5-1.40.3
Locomotion velocity, hab. session 11.31.93.1-1.3-1.5-1.0-1.11.1-1.61.5-1.61.7-1.8-1.10.8
Time in familiar zone, hab. session 20.91.03.11.21.01.21.2-1.20.4-0.60.4-0.4-1.0-1.7-0.8
Time in novel zone, hab. session 21.21.34.10.70.60.40.5-0.51.2-1.21.4-1.32.01.7-0.6
Total zone transitions, hab. session 20.40.52.1-0.8-0.4-0.9-0.80.8-0.30.3-0.40.20.81.40.6
Total locomotion distance, hab. session 20.50.71.0-0.9-0.9-1.0-0.90.9-0.80.9-0.90.9-0.40.30.8
Locomotion velocity, hab. session 20.60.81.2-1.1-0.9-1.0-1.01.0-1.01.0-1.11.0-0.50.20.9
Novel to familiar place preference ratio2.73.55.71.91.91.61.6-1.62.2-2.12.4-2.12.21.3-1.2
Novelty place preference3.44.46.82.22.21.91.9-1.92.4-2.32.6-2.32.21.1-1.5
Time in novel zone, NPP test4.35.28.02.42.42.12.1-2.12.6-2.52.8-2.62.41.2-1.6
Total zone transitions, NPP test0.40.62.2-0.9-0.6-1.0-0.90.9-0.40.4-0.50.40.71.50.6
Total locomotion distance, NPP test1.11.62.4-1.5-1.4-1.5-1.51.5-1.01.2-1.01.20.21.31.1
Locomotion velocity, NPP test1.42.13.1-1.8-1.6-1.7-1.71.7-1.31.4-1.41.4-0.21.01.3
Intraocular pressure1.52.44.5-2.1-1.8-2.0-1.81.8-1.51.6-1.41.5-0.50.51.0
Delta distance traveled before/after self-admin0.10.10.4-0.0-0.10.00.0-0.0-0.40.2-0.50.3-0.6-0.60.1
Delta ambulatory time before/after self-admin0.10.20.50.50.30.50.5-0.5-0.0-0.2-0.1-0.2-0.4-0.7-0.4
Parametrial fat weight0.30.72.10.50.90.50.4-0.41.0-0.90.9-1.01.51.2-0.1
Pavlov. Cond. lever latency6.17.711.13.23.03.33.3-3.32.9-2.92.8-2.71.2-0.9-2.5
Pavlov. Cond. magazine entry latency0.20.30.5-0.7-0.3-0.7-0.60.6-0.60.5-0.70.4-0.20.20.5
Pavlov. Cond. change in total contacts2.22.44.0-1.8-1.4-2.0-1.91.9-1.61.5-1.61.3-0.30.91.5
Pavlov. Cond. index score2.53.24.7-2.1-1.7-2.2-2.02.0-2.01.9-2.01.7-1.00.41.5
Pavlov. Cond. latency score2.43.04.6-2.0-1.7-2.1-2.02.0-2.01.8-1.91.7-0.90.41.5
Pavlov. Cond. lever contacts5.56.79.7-3.0-2.7-3.1-3.03.0-2.82.7-2.72.5-1.20.72.3
Pavlov. Cond. magazine entry number0.30.40.90.70.40.80.7-0.70.9-0.70.9-0.60.50.1-0.5
Pavlov. Cond. intertrial magazine entries0.20.30.5-0.7-0.7-0.5-0.50.5-0.60.6-0.50.6-0.5-0.20.1
Pavlov. Cond. lever-magazine prob. diff.2.63.24.4-2.0-1.7-2.1-1.91.9-2.11.9-2.11.8-1.20.11.5
Pavlov. Cond. response bias2.93.65.4-2.3-1.9-2.3-2.22.2-2.12.0-2.11.8-0.90.51.6
Pavlov. Cond. lever latency2.53.65.41.81.91.61.6-1.62.2-2.12.3-2.22.31.4-1.4
Pavlov. Cond. magazine entry latency0.10.21.00.40.40.50.5-0.50.1-0.20.1-0.2-0.5-1.0-0.3
Pavlov. Cond. change in total contacts0.71.75.4-0.7-0.6-0.5-0.50.5-1.41.1-1.51.3-2.3-2.30.7
Pavlov. Cond. index score0.50.82.8-0.4-0.4-0.3-0.20.2-1.00.7-1.00.8-1.6-1.70.4
Pavlov. Cond. latency score0.61.03.3-0.5-0.6-0.4-0.30.3-1.20.9-1.11.0-1.8-1.80.4
Pavlov. Cond. lever contacts1.82.74.5-1.5-1.6-1.3-1.31.3-2.01.8-2.01.8-2.1-1.31.2
Pavlov. Cond. magazine entry number0.60.83.70.30.30.1-0.00.00.9-0.60.9-0.71.71.9-0.2
Pavlov. Cond. intertrial magazine entries0.10.20.3-0.6-0.4-0.6-0.50.5-0.40.5-0.30.30.00.50.3
Pavlov. Cond. lever-magazine prob. diff.0.50.83.3-0.4-0.4-0.2-0.20.2-1.00.7-1.00.8-1.7-1.80.4
Pavlov. Cond. response bias1.21.64.1-1.0-1.0-0.8-0.70.7-1.51.3-1.51.4-2.0-1.60.8
Time in closed arm before self-admin0.50.81.71.01.31.01.0-1.00.9-1.10.7-0.90.5-0.2-0.5
Time in closed arm after self-admin0.20.20.60.60.50.60.6-0.60.1-0.3-0.1-0.1-0.5-0.80.1
Time in open arm before self-admin0.81.01.7-1.3-1.2-1.3-1.31.3-0.60.9-0.30.70.31.20.6
Time in open arm after self-admin0.80.91.8-1.3-1.4-1.3-1.31.3-0.60.9-0.40.60.21.00.1
Bone: periosteal estimation1.53.65.7-2.4-2.3-2.2-1.91.9-2.22.0-1.92.0-1.30.01.2
Bone: periosteal perimeter0.50.91.8-1.3-1.2-1.3-1.11.1-0.90.9-0.70.8-0.10.90.5
Bone: post-yield work1.83.25.4-2.3-2.3-2.1-2.22.2-1.61.8-1.41.8-0.31.21.2
Progressive ratio test 1 active lever presses0.10.10.6-0.2-0.3-0.0-0.20.20.00.00.4-0.10.80.6-0.0
Progressive ratio test 1 breakpoint0.10.10.5-0.3-0.4-0.1-0.30.3-0.10.10.3-0.00.70.70.0
Progressive ratio test 1 inactive lever presses0.51.22.1-1.4-1.4-1.4-1.51.5-0.70.9-0.50.60.71.50.5
Progressive ratio test 2 active lever presses0.10.21.00.0-0.2-0.0-0.00.00.2-0.20.7-0.31.00.8-0.2
Progressive ratio test 2 breakpoint0.20.21.20.1-0.10.00.0-0.00.3-0.20.8-0.41.10.8-0.3
Progressive ratio test 2 inactive lever presses0.20.51.4-1.0-1.2-0.8-0.80.8-0.60.8-0.40.7-0.20.3-0.1
Incentive Sensitization - Responses0.00.10.3-0.4-0.5-0.6-0.40.4-0.30.2-0.10.20.30.50.2
Incentive Sensitization - Breakpoint0.00.10.3-0.2-0.3-0.4-0.30.3-0.20.1-0.00.00.40.50.1
Sum of active levers in priming session hrs 5-64.13.95.71.72.01.61.5-1.52.3-2.22.4-2.42.41.3-1.9
Progressive ratio0.10.30.70.40.90.30.4-0.40.5-0.60.2-0.60.70.60.0
Food seeking constrained by brief footshock6.68.213.8-3.6-2.8-3.6-3.73.7-2.62.6-2.72.2-0.31.92.8
Seeking ratio, punishment vs. effort1.94.26.7-2.3-2.6-2.3-2.52.5-2.12.1-1.82.0-1.10.31.7
Retroperitoneal fat weight0.52.45.11.72.21.81.9-1.91.1-1.61.1-1.50.3-1.0-0.9
Reaction time number correct0.00.10.5-0.10.6-0.10.0-0.00.3-0.40.1-0.50.70.7-0.1
Reaction time mean minus median0.32.08.0-0.5-1.40.30.2-0.2-1.21.1-1.11.6-2.6-2.8-0.7
Reaction time mean minus median AUC0.42.46.5-1.1-2.0-0.5-0.50.5-1.71.6-1.52.0-2.6-2.3-0.2
Reaction time num false alarms0.30.51.6-0.4-0.8-0.2-0.20.2-0.70.8-0.50.7-1.2-1.2-0.5
Reaction time num false alarms AUC0.41.02.1-1.2-1.4-0.9-0.90.9-1.01.2-0.91.0-1.0-0.5-0.2
Reaction time trials correct on left0.00.10.5-0.10.6-0.10.0-0.00.3-0.40.1-0.50.70.7-0.1
Reaction time trials on left0.10.20.5-0.00.6-0.00.1-0.10.4-0.40.2-0.50.70.6-0.2
Reaction time mean0.81.85.01.40.81.81.7-1.70.6-0.80.6-0.4-1.1-2.2-1.5
Reaction time mean AUC0.82.05.91.50.81.81.8-1.80.6-0.80.6-0.4-1.3-2.4-1.5
Median of all reaction times1.82.84.82.01.72.22.2-2.21.4-1.61.4-1.3-0.1-1.4-1.6
Reaction time omissions1.32.23.91.30.81.81.6-1.61.8-1.41.9-1.30.8-0.1-2.0
Reaction time false alarm rate0.30.51.2-0.4-1.0-0.1-0.30.3-0.60.8-0.40.7-1.1-1.0-0.5
Reaction time premature initiation rate1.82.74.42.02.02.12.0-2.01.3-1.71.5-1.50.1-1.3-1.2
Reaction time premature initiations0.82.54.71.72.21.91.8-1.81.4-1.71.4-1.70.4-0.8-1.2
Std. dev. reaction times0.41.47.40.3-0.41.01.0-1.0-0.40.3-0.30.8-2.1-2.7-1.2
Reaction time trials completed0.10.20.5-0.00.6-0.00.1-0.10.4-0.40.2-0.50.70.6-0.2
Reaction time trials AUC0.10.20.50.00.70.00.2-0.20.4-0.50.3-0.60.70.6-0.2
Run reversals in cocaine runway, females0.30.31.30.50.40.70.8-0.80.1-0.2-0.0-0.0-0.5-1.1-0.6
Run reversals in cocaine runway, males0.10.10.30.30.20.30.5-0.50.1-0.00.2-0.1-0.0-0.2-0.2
Latency to leave start box in cocaine runway0.60.91.6-0.9-0.8-1.0-1.01.0-1.01.1-0.80.9-0.8-0.11.3
Latency to leave start box in cocaine runway, F0.20.30.70.30.50.10.2-0.20.6-0.40.8-0.60.80.8-0.0
Latency to leave start box in cocaine runway, M3.93.75.3-1.9-2.1-2.1-2.32.3-2.02.0-1.71.9-1.3-0.02.3
Std. dev. time between licks in bursts0.20.30.40.60.60.60.7-0.70.5-0.50.5-0.50.0-0.4-0.5
Total sessions with >9 infusions0.50.61.3-1.0-1.1-0.9-1.01.0-0.90.8-0.20.60.30.70.6
Short access day 1 total inactive lever presses0.71.42.7-1.6-1.2-1.5-1.71.7-0.60.9-0.60.60.71.60.8
Short access day 10 total inactive lever presses0.21.21.9-1.4-1.3-1.1-1.31.3-0.71.2-1.31.0-0.70.40.6
Short access day 1 total infusions0.51.01.6-1.2-1.3-1.2-1.31.3-0.70.8-0.20.60.61.20.6
Short access day 10 total infusions0.20.31.4-0.20.00.0-0.10.10.4-0.30.6-0.41.21.0-0.0
Short access total infusions0.20.31.1-0.6-0.6-0.5-0.60.6-0.20.20.40.01.01.00.2
Short access day 1 locomotion1.01.72.61.11.41.21.2-1.21.5-1.51.6-1.51.40.5-1.2
Short access day 10 total locomotion0.31.32.61.41.51.61.5-1.50.6-1.00.7-0.9-0.1-1.2-0.5
Short access total locomotion0.50.71.10.70.91.00.9-0.90.8-0.91.0-0.90.90.1-0.6
One hour access (0.3 mA shock)0.30.30.7-0.6-0.8-0.6-0.70.7-0.50.60.10.40.30.60.1
Compulsive drug intake0.10.10.30.10.60.10.3-0.3-0.2-0.1-0.2-0.1-0.3-0.5-0.0
One hour access (shock baseline)0.20.52.0-0.6-0.9-0.6-0.70.7-0.00.20.40.11.01.40.2
Social response proportion2.32.94.31.92.02.12.1-2.11.7-1.91.7-1.50.8-0.5-1.5
Social responses0.30.40.8-0.9-0.8-0.8-0.70.7-0.70.6-0.70.8-0.30.20.5
Social time0.10.10.60.00.30.00.1-0.10.4-0.30.3-0.30.70.8-0.4
Soleus weight0.51.57.5-0.40.3-0.3-0.30.31.1-0.80.9-1.12.42.7-0.2
Bone: stiffness4.48.012.7-3.3-3.6-2.9-3.03.0-3.03.1-2.93.2-2.2-0.41.9
Tibialis anterior weight6.723.237.9-6.2-5.5-5.8-5.75.7-4.85.0-4.74.7-2.21.63.7
Time to tail flick, vehicle, before self-admin1.01.22.31.51.51.41.3-1.31.0-1.20.8-1.10.4-0.3-0.1
Time to tail flick, vehicle, after self-admin0.10.10.40.10.1-0.10.1-0.1-0.40.1-0.30.3-0.5-0.50.7
Time to tail flick, test, before self-admin0.50.61.4-0.6-0.7-0.8-0.70.7-0.70.7-0.90.8-0.5-0.01.2
Time to tail flick, test, after self-admin0.90.92.3-0.8-0.4-0.3-0.40.4-1.10.9-1.31.1-1.5-1.30.7
Delta time to tail flick, vehicle, before/after SA0.40.40.8-0.9-0.7-0.8-0.60.6-0.70.7-0.70.7-0.40.10.2
Delta time to tail flick, test, before/after SA0.20.30.70.50.60.70.6-0.60.2-0.20.1-0.2-0.4-0.9-0.5
Tibia length0.20.52.5-0.5-0.5-0.9-0.70.70.10.00.4-0.01.11.60.5
Ambulatory time before self-admin1.54.57.9-2.7-2.7-2.8-2.62.6-1.82.1-1.62.0-0.41.21.5
Ambulatory time after self-admin1.21.93.7-1.5-1.9-1.7-1.61.6-1.51.5-1.11.4-0.70.30.9
Bone: tissue strength0.20.20.4-0.5-0.6-0.3-0.60.6-0.30.6-0.40.5-0.3-0.00.2
Total heroin consumption0.91.12.30.90.80.70.7-0.71.1-1.11.5-1.31.40.8-1.1
Bone: trabecular number0.81.52.3-1.3-1.4-0.8-1.01.0-1.41.3-1.51.4-1.4-1.00.6
Bone: trabecular spacing0.10.10.4-0.2-0.3-0.2-0.10.1-0.40.4-0.20.4-0.6-0.5-0.0
Bone: trabecular thickness0.20.30.60.70.60.60.6-0.60.2-0.50.4-0.4-0.2-0.8-0.3
Bone: trabecular tissue density2.95.06.9-2.5-2.6-2.6-2.42.4-2.42.5-2.22.4-1.60.11.7
Water consumed over 24 hours0.81.62.6-1.5-1.6-1.3-1.41.4-1.31.3-1.31.4-0.8-0.00.9
Number of responses in last shaping day1.11.45.9-0.30.4-0.4-0.50.50.9-0.61.4-1.12.32.40.1