Hub : Genes

Vwce

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Vwce 0.18 0.07 0.0e+00 0.2 0.22 0.23 0.23 1.8e-22 1.5e-25 5.9e-26 6.6e-26
2 Brain alternative polyA XM_039079810.1 0.06 0.03 5.3e-04 0.01 0.02 0.02 0.01 2.2e-02 6.3e-03 9.7e-03 4.6e-02
3 Liver mRNA stability Vwce 0.03 0.02 3.8e-03 0 0.01 0 0 3.1e-01 4.3e-02 1.5e-01 2.0e-01
4 Liver isoform ratio NM_001271311.2 0.04 0.03 3.0e-03 0 0.01 0 0 1.3e-01 3.0e-02 1.5e-01 3.6e-01
5 NAcc alternative polyA NM_001271311.2 0.02 0.02 9.6e-03 0.02 0.01 0.02 0.01 1.9e-03 1.5e-02 7.1e-04 7.7e-03
6 PL gene expression Vwce 0.04 0.03 1.1e-03 0.03 0.02 0.02 0.02 3.0e-04 4.4e-03 2.4e-03 1.8e-03
7 NAcc alternative polyA XM_039079810.1 0.1 0.05 5.2e-13 0.1 0.11 0.09 0.12 1.1e-11 4.6e-13 6.1e-11 3.6e-13
8 NAcc alternative polyA XM_039079810.1 0.08 0.04 1.6e-09 0.09 0.09 0.08 0.09 1.7e-10 4.4e-10 2.4e-09 3.4e-10
9 NAcc isoform ratio XM_039079810.1 0.11 0.06 2.6e-10 0.09 0.1 0.09 0.08 2.2e-10 1.6e-11 1.2e-10 6.7e-10
10 Liver alternative polyA NM_001271311.2 0.05 0.04 1.2e-03 0.02 0.01 0.01 0.02 1.2e-03 1.3e-02 6.7e-03 1.9e-03
11 Brain gene expression Vwce 0.04 0.02 9.7e-05 0.03 0.03 0.03 0.03 1.2e-03 5.0e-04 7.1e-04 4.7e-04
12 NAcc isoform ratio NM_001271311.2 0.05 0.04 7.1e-05 0.04 0.05 0.04 0.04 3.5e-05 3.4e-06 1.4e-05 1.1e-05
13 Adipose alternative TSS XM_039079810.1 0.03 0.02 9.8e-03 0.03 0.01 0.02 0.02 5.1e-04 3.3e-02 3.2e-03 1.8e-03
14 Adipose alternative TSS XM_039079810.1 0.05 0.03 3.4e-04 0.04 0.03 0.04 0.04 1.7e-05 4.1e-04 5.8e-05 2.1e-05
15 Liver alternative polyA XM_039079810.1 0.18 0.08 2.4e-10 0.08 0.07 0.07 0.08 1.9e-09 3.8e-08 2.4e-08 6.6e-09
16 Liver alternative polyA XM_039079810.1 0.13 0.06 1.1e-07 0.06 0.04 0.04 0.05 3.8e-07 5.0e-05 2.9e-05 6.0e-06
17 Liver isoform ratio XM_039079810.1 0.07 0.03 3.6e-07 0.04 0.04 0.03 0.04 2.9e-05 4.0e-05 1.7e-04 5.6e-05
18 RMTg alternative polyA XM_039079810.1 0.13 0.09 6.7e-03 0.09 0.07 0.13 0.14 2.0e-03 6.5e-03 2.4e-04 1.1e-04
19 Liver alternative TSS XM_039079810.1 0.03 0.02 4.4e-03 0.01 0.01 0.01 0.01 9.3e-03 9.0e-03 5.4e-02 1.6e-02
20 Adipose gene expression Vwce 0.06 0.03 2.4e-03 0.02 0.01 0.01 0.02 1.1e-03 1.3e-02 3.2e-02 2.9e-03
21 NAcc intron excision ratio chr1_207307612_207323556 0.06 0.04 6.5e-05 0.02 0.04 0.03 0.03 1.0e-03 4.3e-05 1.1e-04 1.8e-04
22 Liver intron excision ratio chr1_207307612_207308714 0.07 0.04 5.8e-06 0.02 0.03 0.03 0.03 1.1e-03 2.3e-04 2.7e-04 2.0e-04
23 Liver alternative polyA NM_001271311.2 0.08 0.05 1.5e-05 0.03 0.03 0.04 0.04 1.2e-04 2.2e-04 4.6e-05 2.2e-05
24 pVTA intron excision ratio chr1_207282696_207301863 0.15 0.1 1.7e-03 0.09 0.06 0.1 0.08 1.3e-04 9.0e-04 3.4e-05 3.1e-04
25 Liver gene expression Vwce 0.22 0.08 0.0e+00 0.17 0.2 0.21 0.21 9.5e-19 2.9e-21 7.3e-23 2.4e-23

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.20.40.9-0.10.2-0.1-0.3-0.7-0.6-0.1-0.2-0.10.80.80.40.70.7-0.9-0.9-0.9-0.4-0.9-0.0-0.71.0-0.10.60.8
Area under the delay curve0.90.92.1-0.6-0.7-0.8-0.8-1.1-1.1-0.50.1-0.31.41.20.51.01.0-1.0-1.2-1.2-0.5-1.1-1.2-0.61.1-1.21.20.9
BMI with tail1.44.512.82.31.81.91.3-0.1-0.72.6-2.93.40.7-0.6-2.20.90.9-0.4-0.4-0.40.3-3.0-3.3-3.31.8-2.73.23.6
BMI without tail0.61.34.31.30.91.11.00.6-0.01.6-1.31.9-0.5-1.3-1.50.20.20.50.80.81.2-0.8-2.1-1.30.1-1.61.31.5
Body weight1.24.915.02.52.72.42.10.3-0.32.9-3.03.20.1-1.3-2.40.50.50.10.20.2-1.0-2.0-3.2-3.61.3-2.73.93.3
Weight adjusted by age3.03.48.92.61.42.12.01.91.72.5-2.53.0-1.8-2.0-2.8-1.6-1.61.41.51.50.7-0.3-2.3-0.8-0.7-1.91.31.2
Bone surface0.50.93.00.4-0.2-0.1-0.1-0.8-0.50.4-0.70.70.80.9-0.30.80.8-1.0-1.1-1.10.3-1.1-1.6-0.91.3-1.71.71.6
Bone volume0.40.81.9-0.0-0.0-0.2-0.4-1.0-0.6-0.1-0.30.21.01.10.30.90.9-1.3-1.3-1.3-0.1-1.1-0.7-0.91.4-0.81.11.2
Breakpoint value in progressive ratio session2.62.96.42.01.51.92.12.52.21.9-1.51.8-2.1-2.0-2.0-2.1-2.11.91.91.91.51.3-0.4-0.1-1.40.2-0.2-0.2
Number of licking bursts0.30.31.3-0.20.3-0.1-0.2-0.5-0.7-0.0-0.0-0.10.80.40.40.70.7-0.8-0.8-0.8-0.3-0.5-0.5-0.90.8-1.10.60.6
Context. condit. distance diff. score0.10.10.8-0.0-0.0-0.1-0.1-0.4-0.4-0.0-0.10.10.20.00.0-0.1-0.1-0.4-0.1-0.1-0.2-0.5-0.6-0.30.3-0.90.60.5
Locomotion velocity, session 10.60.71.50.8-0.10.60.61.21.10.8-0.50.8-1.1-1.0-1.1-0.7-0.71.21.11.10.60.30.30.8-1.00.5-0.7-0.7
Locomotion distance, session 10.91.12.91.41.61.71.41.41.11.5-1.31.3-0.8-1.1-1.3-0.4-0.41.21.01.0-0.8-0.20.8-0.7-0.70.8-0.1-0.2
Locomotion velocity, session 21.21.44.31.72.11.91.70.80.71.9-1.71.7-0.6-1.0-1.5-0.3-0.30.70.40.4-1.1-0.5-0.1-1.60.2-0.11.11.0
Locomotion distance, session 20.91.23.21.41.81.71.51.31.01.4-1.41.0-0.8-1.2-1.2-0.5-0.51.41.21.2-1.10.10.8-0.8-0.90.90.0-0.3
Locomotion velocity, session 31.51.84.60.20.90.3-0.0-1.4-1.30.4-0.90.61.20.70.01.81.8-1.4-1.1-1.1-1.7-2.1-0.9-2.11.7-1.22.12.1
Locomotion distance, session 30.40.41.8-0.7-0.6-0.7-0.7-0.7-0.8-0.70.4-0.60.50.70.61.31.3-0.8-0.4-0.4-0.2-0.3-0.40.00.5-0.60.50.2
Stereotopy head waving bouts, day 30.60.72.5-0.20.40.1-0.3-0.8-0.90.1-0.00.11.30.70.31.21.2-0.6-0.8-0.8-1.6-1.5-0.1-1.21.0-0.30.91.0
Stereotopy head waving duration, day 30.50.61.8-0.10.3-0.0-0.2-0.7-0.90.2-0.10.31.10.30.01.01.0-0.5-0.6-0.6-1.3-1.2-0.8-1.20.9-0.81.21.2
Locomotion velocity, session 70.80.92.1-0.6-0.3-0.6-0.6-1.2-1.1-0.60.3-0.51.41.10.71.21.2-0.9-1.4-1.4-0.9-0.9-0.7-0.71.2-1.00.90.9
Locomotion distance, session 70.40.51.5-0.7-0.5-0.7-0.6-0.7-1.1-0.50.5-0.51.20.70.50.80.8-0.5-0.9-0.9-0.5-0.7-0.7-0.30.8-1.00.70.7
Stereotopy head waving bouts, day 70.30.31.70.6-0.30.10.20.00.20.5-0.70.8-0.00.0-0.7-0.1-0.1-0.1-0.2-0.20.4-0.5-1.3-0.20.3-1.20.90.7
Stereotopy head waving duration, day 70.50.71.91.10.60.80.90.30.41.1-1.31.3-0.4-0.4-1.2-0.2-0.20.20.10.10.4-0.3-1.4-0.70.2-1.11.30.9
Locomotion velocity, session 80.20.20.7-0.3-0.6-0.4-0.20.30.0-0.20.5-0.2-0.1-0.2-0.0-0.3-0.30.50.40.40.60.7-0.80.6-0.5-0.90.3-0.6
Locomotion distance, session 80.20.21.50.20.40.30.1-0.2-0.30.3-0.50.20.40.1-0.10.40.4-0.1-0.1-0.1-1.2-0.9-0.3-0.70.3-0.60.80.5
Degree of sensitization distance0.50.51.70.50.60.50.2-0.1-0.40.7-0.50.80.90.1-0.4-0.3-0.30.0-0.7-0.7-1.1-1.3-0.7-1.20.7-0.60.71.1
Degree of sensitization stereotypy0.70.82.81.2-0.10.60.70.50.71.1-1.31.4-0.8-0.5-1.3-0.7-0.70.30.30.30.8-0.2-1.7-0.1-0.0-1.41.10.8
Conditioned locomotion0.30.31.20.70.10.40.60.50.30.8-0.80.80.1-0.3-1.0-0.1-0.10.40.20.20.6-0.1-1.1-0.1-0.0-1.00.80.6
Cocaine response after cond. corrected0.20.20.40.4-0.20.20.10.50.30.4-0.30.6-0.4-0.5-0.7-0.5-0.50.60.60.60.3-0.2-0.30.4-0.5-0.3-0.3-0.2
Cocaine response after cond. not corrected0.20.20.40.4-0.40.20.10.40.60.3-0.30.5-0.5-0.4-0.6-0.6-0.60.50.40.40.0-0.20.10.7-0.40.1-0.6-0.3
Cocaine response before conditioning0.20.31.10.30.10.30.20.20.90.1-0.2-0.0-0.70.0-0.0-0.9-0.90.0-0.2-0.2-0.50.41.00.5-0.11.1-0.7-0.5
Saline control response1.11.52.91.71.51.71.71.61.31.6-1.71.6-1.1-1.3-1.6-1.2-1.21.31.01.01.10.7-0.3-0.5-0.8-0.10.2-0.1
Bone: connectivity density0.30.51.70.80.50.50.4-0.1-0.10.8-1.00.90.20.1-0.70.50.5-0.4-0.3-0.30.2-0.9-0.9-1.00.7-0.91.31.2
Bone: cortical apparent density0.60.71.60.81.11.01.11.11.00.8-0.50.3-1.0-1.0-0.6-1.0-1.00.80.90.9-0.60.90.90.0-0.71.3-0.5-0.4
Bone: cortical area0.20.32.10.31.20.70.5-0.10.10.3-0.3-0.1-0.10.20.2-0.1-0.1-0.4-0.3-0.3-1.4-0.01.2-0.70.31.1-0.30.0
Bone: cortical porosity0.20.20.60.2-0.4-0.10.20.60.50.1-0.10.3-0.5-0.4-0.5-0.1-0.10.50.50.50.60.8-0.60.7-0.6-0.5-0.2-0.4
Bone: cortical porosity0.40.51.10.5-0.20.20.61.00.70.5-0.40.6-0.7-0.7-0.9-0.3-0.30.90.90.91.01.0-0.80.6-0.8-0.7-0.1-0.4
Bone: cortical thickness1.83.06.01.72.52.22.32.02.01.6-1.30.9-2.0-1.9-1.3-2.0-2.01.71.81.8-0.41.81.8-0.2-1.62.2-1.0-1.1
Bone: cortical thickness0.30.41.10.30.40.40.70.50.70.2-0.1-0.1-0.9-1.0-0.4-0.4-0.40.50.80.8-0.11.00.90.6-0.71.0-0.6-0.6
Bone: cortical tissue density0.60.81.60.91.21.11.31.21.00.9-0.60.5-1.1-1.2-0.8-1.1-1.10.91.01.0-0.50.90.80.0-0.81.2-0.4-0.4
Condit. Reinf. active minus inactive responses1.82.04.41.91.31.81.72.11.81.8-1.61.6-1.5-1.5-1.8-1.3-1.31.51.41.40.20.41.10.0-1.11.5-0.7-0.3
Condit. Reinf. active-inactive response ratio2.83.16.91.90.91.71.82.62.41.7-1.41.5-1.9-2.0-2.0-2.1-2.12.11.81.81.31.21.20.9-1.81.6-1.4-1.1
Condit. Reinf. active responses1.31.63.81.81.91.91.61.41.21.7-1.61.5-1.1-1.1-1.4-0.8-0.80.80.90.9-1.1-0.41.4-0.8-0.41.8-0.30.2
Condit. Reinf. inactive responses0.60.74.50.11.10.5-0.0-0.9-0.80.1-0.30.00.40.60.50.60.6-0.9-0.5-0.5-2.1-1.30.8-1.51.00.70.50.9
Incentive salience index mean0.81.02.61.31.61.61.21.21.01.4-1.31.1-0.8-0.8-1.0-0.5-0.50.70.70.7-1.1-0.31.4-0.7-0.31.6-0.30.1
Condit. Reinf. lever presses0.40.53.40.00.80.30.0-0.6-0.60.1-0.2-0.00.60.70.30.60.6-0.9-0.7-0.7-1.8-1.00.8-1.11.00.70.40.8
Condit. Reinf. active minus inactive responses0.30.41.70.50.00.40.30.51.00.3-0.40.2-0.7-0.2-0.4-0.7-0.70.40.20.21.00.21.00.7-0.51.1-1.3-0.6
Condit. Reinf. active-inactive response ratio0.40.42.10.4-0.4-0.1-0.2-0.6-0.10.4-0.50.80.10.3-0.50.30.3-0.7-0.5-0.50.5-1.2-1.4-0.30.8-1.10.81.2
Condit. Reinf. active responses0.30.41.90.50.30.60.40.71.00.4-0.50.2-0.5-0.1-0.4-0.8-0.80.40.00.00.90.31.20.5-0.41.2-1.4-0.7
Condit. Reinf. inactive responses0.70.85.3-0.30.20.10.00.80.7-0.40.5-0.8-0.30.10.5-0.7-0.70.60.20.20.21.12.30.9-0.81.9-1.9-1.6
Condit. Reinf. lever presses0.40.62.41.21.41.20.90.30.51.1-1.61.3-0.2-0.0-0.7-0.5-0.5-0.2-0.3-0.30.4-0.5-0.1-1.20.5-0.10.30.7
Condit. Reinf. lever reinforcers received0.50.81.61.00.71.00.91.01.30.8-0.90.7-1.0-0.5-0.8-1.2-1.20.70.40.41.10.41.00.3-0.61.0-1.2-0.5
Conditioned reinforcement - actives0.50.52.4-0.6-1.2-0.8-0.70.20.5-0.70.9-0.7-0.40.30.4-0.4-0.4-0.2-0.1-0.10.30.40.61.5-0.50.9-1.5-0.9
Conditioned reinforcement - inactives0.60.62.5-0.60.0-0.3-0.7-0.8-0.7-0.60.6-0.60.71.00.90.80.8-1.1-1.1-1.1-1.6-0.81.1-0.30.90.7-0.40.1
Conditioned locomotion1.31.52.7-1.3-0.7-1.1-1.3-1.5-1.3-1.21.1-1.21.41.61.41.31.3-1.6-1.5-1.5-1.7-1.11.30.11.10.8-0.60.1
Patch foraging indifference point 0 sec0.20.31.60.51.20.80.70.20.10.4-0.50.4-0.0-0.1-0.2-0.3-0.30.2-0.0-0.0-1.00.10.6-1.00.10.50.30.2
Patch foraging indifference point AUC1.31.56.21.42.52.01.81.11.21.5-1.20.9-0.8-0.9-0.8-1.1-1.10.80.70.7-0.90.51.6-1.2-0.41.7-0.5-0.2
Delay disc. indifference point, 0s delay1.41.54.6-0.4-0.7-0.6-0.9-1.5-1.2-0.1-0.20.31.81.20.21.21.2-1.3-1.4-1.4-0.6-1.8-2.1-0.91.3-1.91.51.4
Delay disc. indifference point, 16s delay0.30.30.9-0.10.1-0.1-0.2-0.5-0.50.0-0.20.00.60.70.20.50.5-0.6-0.8-0.8-0.9-0.8-0.3-0.70.80.20.80.7
Delay disc. indifference point, 2s delay1.51.73.6-1.0-1.3-1.3-1.4-1.6-1.4-0.90.5-0.61.81.80.91.11.1-1.4-1.9-1.9-0.5-1.5-1.2-0.31.5-1.51.10.9
Delay disc. indifference point, 24s delay0.20.20.8-0.40.2-0.2-0.2-0.2-0.6-0.20.1-0.40.70.40.40.50.5-0.2-0.4-0.4-0.9-0.40.4-0.50.40.40.20.2
Delay disc. indifference point, 4s delay1.11.23.1-0.6-0.2-0.6-0.7-1.6-1.4-0.4-0.1-0.31.81.10.61.21.2-1.1-1.2-1.2-0.9-1.2-1.2-1.11.2-1.51.71.2
Delay disc. indifference point, 8s delay1.21.22.6-1.2-1.3-1.4-1.2-1.1-1.3-1.00.8-0.91.61.20.91.21.2-0.8-1.1-1.10.1-0.6-1.6-0.00.8-1.51.10.5
Indifference point function ln k1.72.44.9-1.8-2.2-2.1-2.2-1.8-2.0-1.71.5-1.01.81.51.41.71.7-1.6-1.5-1.5-0.5-1.4-1.20.51.2-1.70.30.6
Indifference point function log k1.72.44.9-1.8-2.2-2.1-2.2-1.8-2.0-1.71.5-1.01.81.51.41.71.7-1.6-1.5-1.5-0.5-1.4-1.20.51.2-1.70.30.6
Patch foraging total patch changes 0 sec0.20.31.50.41.20.80.80.30.20.4-0.30.2-0.3-0.3-0.2-0.4-0.40.50.30.3-0.90.40.9-0.7-0.20.70.1-0.2
Patch foraging total patch changes 12 sec2.83.610.82.63.33.03.01.71.72.5-2.32.1-1.8-2.1-2.1-1.7-1.71.71.81.8-0.31.00.4-1.6-1.00.60.80.2
Patch foraging total patch changes 18 sec0.60.81.80.81.41.21.11.01.20.8-0.70.4-0.8-0.7-0.4-1.2-1.21.00.70.7-0.10.81.1-0.3-0.81.1-0.7-0.8
Patch foraging total patch changes 24 sec2.63.116.42.34.03.02.60.80.62.5-2.32.1-0.4-1.2-1.5-0.6-0.60.70.60.6-1.5-0.40.3-3.30.40.21.51.4
Patch foraging total patch changes 6 sec0.30.42.50.41.40.80.6-0.4-0.30.4-0.40.30.3-0.00.00.10.1-0.4-0.2-0.2-1.6-0.20.1-1.40.4-0.11.10.6
Patch foraging time to switch 0 sec0.61.05.30.5-0.6-0.2-0.2-0.5-0.30.4-0.91.10.40.6-0.60.40.4-0.6-0.7-0.70.5-1.1-2.3-0.61.0-2.21.81.4
Patch foraging water rate 0 sec0.81.27.6-1.00.3-0.2-0.3-0.2-0.2-1.01.5-1.6-0.3-0.01.2-0.0-0.00.00.30.3-1.40.92.80.6-0.52.5-1.6-1.4
Patch foraging water rate 12 sec0.60.92.5-1.4-0.4-0.9-1.0-0.8-0.8-1.51.4-1.50.50.51.40.70.7-0.4-0.2-0.2-1.00.11.60.40.01.3-1.1-0.8
Patch foraging water rate 18 sec0.81.13.0-1.6-0.1-0.8-1.0-0.9-1.4-1.31.7-1.40.90.61.61.31.3-0.8-0.6-0.6-1.1-0.21.4-0.20.50.9-0.6-0.4
Patch foraging water rate 24 sec0.40.61.8-1.3-1.1-1.2-1.1-0.8-0.8-1.31.3-1.20.10.21.10.40.4-0.50.00.0-0.30.20.20.8-0.10.1-0.3-0.5
Patch foraging water rate 6 sec0.60.92.5-1.4-0.3-0.8-0.9-0.7-0.9-1.31.4-1.60.50.41.40.80.8-0.2-0.1-0.1-0.90.31.60.4-0.11.1-1.2-0.9
Seeking ratio, delayed vs. immediate footshock0.50.62.6-0.01.20.50.2-0.9-0.70.3-0.2-0.10.90.60.40.50.5-0.7-0.6-0.6-1.6-0.81.3-1.30.71.20.20.5
Distance traveled before self-admin1.11.12.61.60.91.21.20.81.21.5-1.61.6-1.1-0.9-1.3-1.4-1.40.50.60.60.40.1-1.3-0.6-0.4-0.21.20.6
Distance traveled after self-admin0.10.10.50.60.40.50.40.00.60.5-0.70.4-0.4-0.2-0.3-0.6-0.6-0.10.10.1-0.20.1-0.0-0.2-0.1-0.00.00.0
Extensor digitorum longus weight2.39.023.04.54.44.34.11.81.34.6-4.84.7-1.3-2.6-4.1-1.0-1.01.41.31.3-0.0-1.1-2.5-3.80.4-1.83.43.1
Bone: elastic displacement1.01.13.4-0.4-0.8-0.4-0.01.00.8-0.40.8-0.7-0.9-0.8-0.0-1.2-1.21.11.21.20.61.41.11.8-1.51.3-1.4-1.7
Bone: elastic work1.01.32.60.91.01.11.31.61.20.9-0.40.5-1.4-1.5-1.0-1.6-1.61.41.51.50.21.30.80.4-1.41.1-0.7-1.0
Bone: endosteal estimation2.45.29.1-2.0-1.3-2.0-2.5-2.9-3.0-1.81.5-1.32.93.02.22.62.6-3.0-3.0-3.0-1.4-2.7-0.7-1.22.9-1.41.11.8
Bone: endosteal perimeter3.47.112.6-2.3-2.1-2.6-3.0-3.5-3.3-2.21.7-1.53.23.52.43.13.1-3.5-3.5-3.5-1.3-3.0-1.3-0.93.4-1.91.32.1
Epididymis fat weight1.63.79.9-1.5-0.6-1.4-1.7-2.6-2.5-1.31.0-1.22.52.01.82.22.2-2.4-2.4-2.4-3.1-2.1-0.5-1.42.3-1.01.71.5
Delta time in closed arm before/after self-admin1.81.76.51.62.52.11.90.90.61.7-1.91.5-0.5-1.6-1.3-0.7-0.71.41.41.4-0.60.1-0.3-1.8-0.70.11.00.5
Delta time in open arm before/after self-admin1.11.02.21.41.41.51.51.31.21.3-1.21.2-1.3-1.0-1.2-0.9-0.90.90.80.8-0.30.40.7-0.5-0.31.1-0.10.3
Diff in mean of infusions in LGA sessions2.12.45.01.81.51.82.02.22.01.7-1.41.5-1.8-1.9-1.8-1.8-1.81.81.71.71.31.3-0.3-0.1-1.30.2-0.1-0.3
Delay discount exponential model param0.91.02.20.70.70.90.91.11.10.5-0.10.4-1.5-1.2-0.6-1.0-1.01.01.31.30.51.11.10.6-1.11.2-1.2-0.9
Extinction: sum of active levers before priming1.21.22.51.51.31.31.51.40.61.4-1.31.6-1.0-1.1-1.5-0.4-0.41.00.90.90.50.2-1.2-1.0-0.1-0.61.10.9
Active lever presses in extinction session 61.51.53.01.51.01.41.61.71.71.3-1.11.2-1.7-1.4-1.5-1.6-1.61.21.21.20.71.1-0.10.0-0.90.70.1-0.1
Bone: final force0.40.73.01.11.71.41.20.40.51.2-1.11.0-0.4-0.5-0.8-0.6-0.60.10.20.2-0.6-0.30.5-1.20.20.70.30.5
Bone: final moment0.40.62.91.11.71.41.20.40.51.1-1.00.9-0.4-0.5-0.7-0.7-0.70.20.20.2-0.7-0.20.6-1.10.10.80.20.5
Food consumed during 24 hour testing period0.30.31.2-0.5-0.7-0.5-0.4-0.10.3-0.60.8-0.6-0.7-0.10.4-0.4-0.40.00.20.20.30.60.81.1-0.50.7-0.8-0.9
Glucose1.92.96.2-2.0-2.4-2.3-2.5-1.8-1.9-2.01.7-1.72.42.01.91.81.8-1.5-1.9-1.9-0.8-1.4-0.50.71.2-0.9-0.10.2
Heart weight0.81.12.9-1.2-0.9-1.1-1.2-0.9-1.6-0.80.9-0.71.51.00.91.71.7-0.9-1.0-1.00.6-1.1-0.8-0.30.9-0.80.10.6
Delay discount hyperbolic model param1.01.12.60.70.80.90.91.21.20.5-0.10.4-1.6-1.3-0.6-1.1-1.11.11.41.40.61.21.30.6-1.21.3-1.3-1.0
Intermittent access intake day 1-15 change1.00.94.3-0.7-0.6-0.5-0.40.20.6-0.81.0-1.1-0.60.10.7-0.8-0.80.20.20.2-0.01.12.11.5-0.71.7-1.8-1.5
Intermittent access intake escalation0.70.73.8-0.3-0.3-0.1-0.10.40.8-0.50.6-0.8-0.8-0.10.4-0.9-0.90.40.30.3-0.21.01.91.2-0.71.5-1.6-1.3
Intermittent access intake escalation 20.70.73.10.30.70.60.60.71.00.10.0-0.2-1.1-0.50.0-1.2-1.20.50.60.6-0.51.01.80.4-0.71.7-1.0-1.0
Intermitt. access day 1 inactive lever presses1.51.63.4-1.0-0.6-0.9-1.3-1.5-1.7-0.90.7-0.51.51.51.11.91.9-1.6-1.7-1.7-1.0-1.7-0.2-0.61.60.00.40.8
Intermitt. access day 15 inactive lever presses1.92.110.1-0.11.30.5-0.3-1.6-1.50.1-0.20.21.31.40.71.61.6-1.8-1.8-1.8-3.2-2.10.8-2.22.00.31.01.3
Intermitt. access escalation Index1.61.43.2-1.1-0.2-0.8-0.9-1.5-1.7-0.90.7-1.21.71.31.21.81.8-1.3-1.2-1.2-1.8-1.10.8-0.61.10.10.30.4
Intermittent access day 1 total infusions3.43.98.4-0.9-0.5-1.0-1.5-2.6-2.5-0.70.3-0.32.62.31.12.62.6-2.6-2.6-2.6-2.3-2.9-0.7-1.62.6-1.31.61.9
Intermittent access day 15 total infusions2.22.54.3-1.6-1.1-1.4-1.7-2.0-1.6-1.61.5-1.61.62.11.81.61.6-2.0-2.0-2.0-2.1-1.21.70.31.40.8-0.7-0.1
Intermittent access terminal intake (last 3 days)1.01.04.7-0.40.0-0.3-0.7-1.3-0.9-0.40.3-0.41.01.30.70.90.9-1.5-1.5-1.5-2.2-1.41.2-0.61.30.50.00.6
Intermittent access total infusions1.61.85.1-0.8-0.4-0.7-1.1-1.8-1.6-0.70.5-0.61.61.71.01.61.6-1.9-1.9-1.9-2.3-1.80.7-0.71.7-0.00.30.9
Intermittent access day 1 locomotion3.03.27.8-0.50.3-0.4-0.9-2.1-2.4-0.2-0.10.12.31.80.72.62.6-2.2-2.2-2.2-2.3-2.8-0.4-2.02.5-1.01.62.1
Intermittent access day 15 total locomotion1.01.13.40.10.60.3-0.2-1.1-1.10.3-0.30.51.00.90.11.01.0-1.3-1.3-1.3-1.9-1.80.1-1.41.6-0.30.71.4
Intermittent access total locomotion3.23.79.9-0.30.5-0.2-0.9-2.3-2.3-0.0-0.30.32.22.10.72.22.2-2.6-2.6-2.6-3.1-3.10.1-2.22.9-0.71.52.2
Intermittent access standard deviation1.21.32.70.3-0.20.30.41.31.60.10.2-0.0-1.5-1.0-0.5-1.5-1.51.21.21.20.71.31.11.5-1.41.6-1.6-1.3
Left kidney weight0.92.45.3-0.90.1-0.6-0.9-1.9-2.2-0.50.2-0.52.01.41.02.32.3-1.9-1.8-1.8-2.0-1.8-1.1-1.82.0-1.21.71.6
Right kidney weight0.41.23.4-0.30.3-0.2-0.4-1.3-1.4-0.1-0.2-0.01.30.90.41.51.5-1.3-1.2-1.2-1.8-1.5-0.8-1.41.5-0.91.31.4
Cocaine induced anxiety0.40.51.00.90.60.80.80.80.80.9-0.70.9-1.0-0.9-0.9-0.9-0.90.70.70.70.00.2-0.2-0.1-0.5-0.30.10.1
Post-drug Anxiety0.91.02.11.30.51.00.91.31.21.2-1.11.5-1.3-1.1-1.3-1.3-1.30.90.90.91.10.2-0.9-0.1-0.6-1.20.10.2
Baseline Anxiety0.70.71.61.10.60.90.81.00.91.0-1.01.3-0.7-0.9-1.1-0.9-0.90.70.70.71.10.1-1.0-0.4-0.4-0.70.40.4
Tail length0.41.12.90.91.41.21.51.20.91.1-0.70.7-1.3-1.7-1.0-0.9-0.91.31.51.5-0.01.2-0.4-0.4-1.0-0.10.6-0.2
Length with tail0.62.17.81.52.31.71.70.1-0.21.8-1.91.6-0.1-0.9-1.20.20.20.10.20.2-2.1-0.6-1.6-2.50.7-1.42.81.8
Length without tail0.61.35.21.01.71.20.9-0.4-0.41.1-1.61.00.60.1-0.50.40.4-0.4-0.7-0.7-2.3-1.1-0.6-2.11.1-0.72.01.5
Times rat made contact with spout0.80.91.60.70.60.81.01.11.30.6-0.60.3-0.9-1.0-0.7-1.1-1.11.20.90.91.31.11.00.6-1.11.1-0.9-0.9
Lifetime Intake1.21.33.1-0.7-0.5-0.7-1.0-1.5-1.4-0.50.4-0.31.51.40.71.51.5-1.6-1.6-1.6-1.8-1.70.2-0.51.5-0.40.40.9
Liver weight, left0.40.71.9-1.3-1.3-1.2-1.1-0.3-0.6-1.21.3-1.40.70.71.10.40.4-0.3-0.5-0.50.40.30.71.0-0.00.6-0.8-0.8
Liver weight, right0.10.22.1-0.2-0.00.0-0.20.00.0-0.20.2-0.50.30.20.3-0.2-0.20.2-0.1-0.1-1.5-0.31.20.3-0.21.0-0.4-0.5
Locomotor activity0.91.46.5-1.00.6-0.1-0.40.3-0.0-1.11.0-1.70.2-0.01.5-0.4-0.40.70.40.4-1.60.92.60.2-1.02.5-1.7-1.8
Locomotor testing distance0.71.16.1-0.90.4-0.1-0.40.30.1-0.91.1-1.40.2-0.11.2-0.2-0.20.80.60.6-1.40.62.40.4-0.92.5-1.6-1.6
Locomotor testing rearing0.71.15.3-0.50.20.0-0.30.60.8-0.60.7-0.9-0.3-0.10.8-1.0-1.00.80.40.4-0.30.72.30.8-1.12.2-2.1-1.7
Locomotion in novel chamber1.51.84.0-1.5-1.8-1.8-2.0-1.8-1.1-1.81.3-1.21.21.91.60.80.8-1.8-1.8-1.8-0.3-1.0-0.20.41.2-0.70.10.2
Locomotion in novel chamber post-restriction0.50.62.1-1.0-1.5-1.1-0.90.1-0.2-1.01.3-1.0-0.00.20.60.10.10.40.20.20.90.70.01.4-0.50.6-0.9-0.9
Fecal boli incidents, locomotor time 10.50.52.31.00.20.70.50.41.50.8-1.00.8-0.6-0.2-0.7-1.4-1.40.20.00.00.70.10.40.3-0.30.4-0.6-0.2
Change in fecal boli incidents, locomotor task2.12.04.3-1.8-1.5-1.8-1.8-1.6-2.1-1.71.5-1.31.61.21.51.91.9-1.2-0.9-0.9-0.1-1.0-1.5-0.00.8-1.40.80.4
Time >=10cm from walls, locomotor time 11.21.22.4-0.8-1.2-1.1-1.3-1.5-1.1-0.80.5-0.41.01.50.81.11.1-1.4-1.5-1.5-1.0-1.4-0.80.01.3-0.80.40.8
Bouts of movement, locomotor time 14.04.48.92.22.12.42.52.53.02.0-2.01.4-2.3-2.2-1.8-2.8-2.82.22.12.11.12.21.50.4-2.11.7-1.7-1.3
Total resting periods, locomotor time 12.52.86.11.81.72.02.02.02.51.7-1.71.1-1.8-1.7-1.4-2.3-2.31.71.51.50.91.71.20.2-1.51.4-1.4-1.0
Rest time, locomotor task time 10.20.20.5-0.5-0.5-0.4-0.4-0.3-0.0-0.30.4-0.60.60.50.50.00.0-0.5-0.5-0.50.20.20.50.40.00.2-0.7-0.5
Distance moved, locomotor task time 10.30.42.2-0.1-0.7-0.5-0.4-0.2-0.7-0.20.30.2-0.10.1-0.20.50.5-0.3-0.0-0.0-0.2-0.6-1.5-0.00.5-1.41.30.8
Vertical activity count, locomotor time 11.11.23.4-1.6-1.7-1.8-1.5-0.8-1.3-1.71.9-1.50.40.81.21.21.2-0.5-0.4-0.40.1-0.0-0.21.00.3-1.00.0-0.3
Time >=10cm from walls, locomotor time 20.10.20.8-0.2-0.9-0.5-0.40.30.4-0.40.4-0.3-0.50.10.2-0.2-0.20.0-0.0-0.00.60.4-0.00.9-0.2-0.3-0.5-0.4
Bouts of movement, locomotor time 24.95.310.13.12.83.23.02.42.63.0-2.72.8-2.3-2.7-2.9-2.8-2.82.22.32.3-0.00.80.7-0.7-1.61.5-0.30.0
Total resting periods, locomotor time 24.54.89.53.02.73.12.92.22.62.9-2.72.7-2.1-2.5-2.8-2.7-2.72.12.02.0-0.20.60.9-0.7-1.41.9-0.5-0.0
Rest time, locomotor task time 20.20.31.1-0.5-0.5-0.5-0.6-0.7-0.3-0.60.3-0.70.70.50.60.30.3-0.4-0.5-0.5-0.2-0.30.50.40.11.1-0.7-0.3
Distance moved, locomotor task time 20.30.41.8-0.2-1.0-0.6-0.10.60.2-0.30.7-0.1-0.8-0.3-0.2-0.4-0.40.30.50.50.90.8-1.00.9-0.4-1.40.5-0.3
Vertical activity count, locomotor time 20.91.02.9-1.2-1.5-1.3-0.70.7-0.2-1.31.7-1.3-0.6-0.30.6-0.0-0.00.80.90.91.41.5-0.11.7-1.0-1.0-0.6-1.2
Light reinforcement 10.20.41.8-0.2-0.3-0.1-0.20.60.7-0.30.4-0.5-0.50.30.3-0.5-0.50.40.20.20.10.61.30.9-0.61.2-1.3-1.1
Light reinforcement 21.11.53.5-1.1-0.5-0.9-1.2-1.3-1.4-0.90.9-0.81.31.71.41.61.6-1.8-1.9-1.9-1.2-1.20.1-0.61.6-0.30.30.5
Bone: marrow area2.65.59.6-2.2-1.4-2.1-2.6-3.0-3.1-2.01.7-1.53.13.12.42.62.6-3.0-3.1-3.1-1.5-2.7-0.7-1.22.9-1.41.11.7
Bone: maximum diameter0.50.92.3-0.30.4-0.1-0.4-1.2-1.0-0.20.0-0.20.91.10.71.11.1-1.4-1.3-1.3-1.5-1.1-0.0-1.21.5-0.20.51.1
Bone: maximum force0.71.24.81.01.61.10.7-0.5-0.51.1-1.21.20.50.3-0.50.50.5-0.9-0.9-0.9-1.1-1.5-0.6-2.21.4-0.61.61.8
Bone: maximum moment0.61.14.30.91.61.10.7-0.4-0.41.1-1.11.10.50.3-0.50.40.4-0.8-0.8-0.8-1.2-1.4-0.5-2.11.3-0.41.41.6
Mean time between licks in bursts0.81.12.51.20.81.11.41.20.91.4-1.21.0-0.8-1.4-1.6-0.6-0.61.31.41.40.00.30.10.2-0.91.50.10.0
Mean num. licks in bursts1.31.54.10.5-0.00.50.71.31.50.2-0.10.1-1.5-1.1-0.7-1.4-1.41.71.51.51.31.41.31.5-1.62.0-1.4-1.5
Cd content in liver0.70.83.3-0.9-1.8-1.2-1.1-0.00.2-1.01.3-0.80.10.60.5-0.4-0.4-0.0-0.3-0.31.20.40.51.8-0.40.2-1.2-1.2
Co content in liver1.51.85.4-1.0-1.2-0.9-0.50.40.7-1.11.6-1.4-0.8-0.50.6-1.0-1.00.70.90.91.61.81.92.3-1.51.7-2.2-2.1
Cu content in liver0.10.10.30.00.50.20.40.1-0.20.20.20.1-0.1-0.5-0.20.20.20.20.50.5-0.20.2-0.3-0.4-0.2-0.30.40.3
Fe content in liver0.10.10.30.30.00.10.20.0-0.10.3-0.40.4-0.4-0.4-0.40.30.3-0.10.40.4-0.2-0.2-0.6-0.10.0-0.40.40.4
K content in liver0.90.82.70.21.10.40.1-0.7-0.80.3-0.60.20.90.80.21.11.1-0.9-1.0-1.0-1.5-1.30.1-1.71.3-0.11.01.3
Mg content in liver0.50.52.00.21.10.60.1-0.3-0.40.3-0.40.20.80.70.30.60.6-0.4-0.8-0.8-1.0-1.20.7-1.40.90.40.30.7
Mn content in liver0.40.41.70.81.20.80.8-0.1-0.20.8-1.10.60.20.2-0.50.20.2-0.3-0.3-0.3-0.1-0.5-0.5-1.30.7-0.41.11.0
Na content in liver0.20.30.70.70.20.50.50.50.80.5-0.80.5-0.6-0.3-0.6-0.6-0.60.50.30.3-0.70.10.40.3-0.40.3-0.2-0.2
Rb content in liver0.70.92.2-1.3-0.4-0.9-1.2-1.2-1.0-1.21.3-1.31.01.11.50.80.8-0.9-0.8-0.8-1.0-0.61.1-0.00.50.7-0.6-0.3
Se content in liver0.50.72.00.60.70.40.4-0.4-0.50.6-1.10.70.60.5-0.40.90.9-0.7-0.7-0.7-0.3-0.9-1.0-1.21.1-1.11.11.4
Sr content in liver4.54.17.92.82.32.72.82.11.92.8-2.72.6-2.0-2.5-2.8-1.9-1.92.12.22.20.50.7-0.5-0.9-1.40.10.90.3
Zn content in liver3.23.58.52.52.92.92.71.81.92.6-2.42.1-1.9-2.3-2.2-1.5-1.51.71.71.7-0.80.31.2-1.2-1.01.50.10.2
Bone: minimum diameter1.93.66.8-1.5-0.0-1.0-1.7-2.4-2.3-1.41.0-1.52.32.62.12.22.2-2.4-2.5-2.5-2.6-2.30.9-1.42.40.10.21.2
Time in familiar zone, hab. session 10.50.42.40.31.50.90.50.10.10.2-0.3-0.00.00.20.3-0.3-0.30.0-0.2-0.2-1.3-0.11.5-0.90.21.2-0.6-0.2
Time in novel zone, hab. session 10.70.63.6-1.0-1.9-1.3-1.1-0.2-0.1-1.01.1-0.7-0.00.20.40.20.2-0.10.10.11.20.4-0.61.6-0.4-0.5-0.6-0.6
Total zone transitions, hab. session 10.40.51.20.70.70.80.91.10.90.7-0.60.5-0.8-0.9-0.8-0.5-0.51.01.01.00.10.70.40.1-0.90.6-0.0-0.5
Total locomotion distance, hab. session 10.10.20.70.40.40.40.20.1-0.10.5-0.50.60.2-0.1-0.30.50.5-0.0-0.1-0.1-0.7-0.8-0.1-0.70.3-0.00.50.5
Locomotion velocity, hab. session 10.30.41.00.91.01.00.80.60.41.0-0.90.9-0.3-0.7-0.80.10.10.50.50.5-0.5-0.40.0-0.7-0.10.20.60.4
Time in familiar zone, hab. session 20.50.52.1-0.7-1.2-0.8-0.60.20.4-0.81.0-0.7-0.10.30.5-0.2-0.20.30.00.00.90.90.21.4-0.60.1-1.1-1.1
Time in novel zone, hab. session 20.40.41.70.71.31.00.80.10.10.8-1.00.7-0.3-0.6-0.5-0.3-0.30.10.40.4-1.1-0.60.4-1.10.10.50.60.6
Total zone transitions, hab. session 20.91.23.01.11.71.61.31.51.21.1-1.00.8-0.9-1.0-0.8-0.7-0.71.20.90.9-0.40.31.5-0.5-0.91.6-0.4-0.7
Total locomotion distance, hab. session 20.40.51.70.81.31.10.80.90.60.9-0.70.6-0.2-0.4-0.50.10.10.60.30.3-0.5-0.31.2-0.6-0.31.1-0.4-0.2
Locomotion velocity, hab. session 20.20.31.30.51.10.90.50.60.30.6-0.50.40.1-0.1-0.30.40.40.3-0.0-0.0-0.7-0.61.2-0.70.01.0-0.3-0.0
Novel to familiar place preference ratio0.80.84.40.70.90.60.7-0.4-0.50.8-1.10.80.1-0.4-0.70.60.6-0.20.20.2-1.1-0.6-1.4-1.40.5-1.32.11.4
Novelty place preference0.70.83.90.50.70.40.5-0.6-0.70.6-0.90.60.3-0.2-0.40.80.8-0.4-0.0-0.0-1.1-0.7-1.5-1.30.7-1.42.01.4
Time in novel zone, NPP test0.90.93.80.80.90.70.7-0.3-0.50.9-1.21.00.2-0.5-0.70.60.6-0.20.10.1-0.9-0.7-1.7-1.50.5-1.52.01.4
Total zone transitions, NPP test1.21.73.51.41.61.71.71.91.51.4-1.31.0-1.4-1.4-1.4-1.0-1.01.71.51.50.60.80.9-0.2-1.31.1-0.4-0.8
Total locomotion distance, NPP test0.30.41.50.41.00.80.70.90.50.5-0.30.1-0.3-0.4-0.3-0.1-0.10.70.50.5-0.10.11.2-0.2-0.51.2-0.4-0.6
Locomotion velocity, NPP test0.20.32.30.00.70.40.40.60.40.10.1-0.4-0.1-0.20.10.10.10.50.40.4-0.20.41.50.0-0.51.4-0.6-0.8
Intraocular pressure0.30.43.50.4-0.30.10.40.70.80.4-0.30.3-0.6-0.7-0.7-0.4-0.40.70.70.71.90.7-0.30.8-0.7-0.1-0.7-0.4
Delta distance traveled before/after self-admin0.30.30.8-0.8-0.8-0.8-0.7-0.5-0.5-0.90.8-0.90.50.30.60.70.7-0.1-0.1-0.1-0.00.10.50.7-0.0-0.4-0.8-0.4
Delta ambulatory time before/after self-admin0.40.41.3-0.9-1.1-0.9-0.7-0.3-0.3-0.90.9-0.90.30.20.50.40.40.00.10.10.60.40.41.1-0.4-0.2-1.1-0.7
Parametrial fat weight3.46.612.5-2.3-1.7-2.3-2.6-3.2-3.3-2.01.5-1.63.43.32.33.23.2-3.4-3.5-3.5-1.5-2.6-1.1-1.13.2-1.71.31.9
Pavlov. Cond. lever latency0.30.32.9-0.4-0.9-0.7-0.4-0.1-0.1-0.40.3-0.2-0.2-0.30.10.30.30.20.30.31.70.4-1.00.7-0.4-0.90.0-0.3
Pavlov. Cond. magazine entry latency0.30.41.00.90.60.70.50.10.30.9-0.81.00.10.3-0.7-0.4-0.4-0.3-0.6-0.6-1.0-0.7-0.2-0.80.8-0.10.51.0
Pavlov. Cond. change in total contacts0.30.31.70.50.60.60.40.30.50.5-0.40.2-0.20.1-0.2-0.8-0.8-0.0-0.2-0.2-0.8-0.11.3-0.10.21.2-0.50.0
Pavlov. Cond. index score0.20.21.00.50.50.50.40.40.60.5-0.30.4-0.20.1-0.3-0.9-0.9-0.0-0.1-0.1-1.00.00.7-0.10.20.8-0.30.1
Pavlov. Cond. latency score0.10.21.30.20.30.30.10.10.30.2-0.00.10.10.4-0.0-0.6-0.6-0.2-0.3-0.3-1.1-0.10.8-0.10.30.8-0.30.1
Pavlov. Cond. lever contacts0.20.22.5-0.20.2-0.0-0.1-0.2-0.1-0.10.3-0.30.40.60.4-0.2-0.2-0.4-0.5-0.5-1.6-0.31.0-0.10.40.8-0.30.0
Pavlov. Cond. magazine entry number0.30.41.3-0.9-0.1-0.6-0.7-0.6-0.9-0.90.6-0.90.70.30.91.11.1-0.2-0.2-0.2-0.1-0.30.2-0.20.1-0.20.1-0.3
Pavlov. Cond. intertrial magazine entries1.21.47.50.31.41.00.81.11.00.10.0-0.5-1.0-0.70.2-1.1-1.11.01.01.0-0.51.22.70.1-1.22.7-1.6-1.6
Pavlov. Cond. lever-magazine prob. diff.0.30.41.20.70.70.80.70.50.70.7-0.50.5-0.3-0.1-0.5-1.0-1.00.10.00.0-1.10.10.9-0.20.11.0-0.30.1
Pavlov. Cond. response bias0.30.31.00.70.70.70.70.30.60.7-0.60.6-0.4-0.1-0.5-0.9-0.9-0.0-0.1-0.1-1.0-0.10.6-0.30.20.7-0.10.4
Pavlov. Cond. lever latency0.60.93.6-1.2-1.9-1.5-0.9-0.2-0.2-1.21.6-1.30.20.00.60.10.10.30.30.30.81.0-0.51.7-0.7-0.4-0.1-1.0
Pavlov. Cond. magazine entry latency3.64.110.53.13.03.02.81.91.92.9-3.23.0-2.3-2.1-2.6-1.6-1.61.21.61.60.20.1-0.1-1.6-0.50.40.50.9
Pavlov. Cond. change in total contacts1.31.84.92.02.22.11.71.11.31.9-2.21.9-1.5-1.0-1.4-1.2-1.20.40.50.5-0.6-0.30.7-1.30.10.9-0.30.5
Pavlov. Cond. index score2.12.78.72.62.72.62.11.11.22.5-3.02.7-1.5-1.2-2.0-1.1-1.10.40.60.6-0.3-0.7-0.2-2.00.30.20.61.3
Pavlov. Cond. latency score1.92.47.92.42.62.41.90.91.02.3-2.82.5-1.2-1.0-1.8-0.9-0.90.20.40.4-0.4-0.8-0.2-2.10.50.10.71.4
Pavlov. Cond. lever contacts1.21.64.41.92.12.01.61.21.31.6-2.01.7-1.2-0.9-1.3-1.4-1.40.70.60.60.0-0.11.0-1.0-0.31.1-0.70.1
Pavlov. Cond. magazine entry number5.06.116.7-3.8-3.5-3.6-3.3-2.0-2.0-3.74.1-3.82.62.63.31.71.7-1.3-1.8-1.8-0.20.21.02.20.40.3-1.4-1.6
Pavlov. Cond. intertrial magazine entries1.01.44.1-1.6-2.0-1.7-1.6-0.5-0.4-1.61.9-1.71.01.31.30.10.1-0.2-0.8-0.81.10.40.41.6-0.10.3-1.1-1.1
Pavlov. Cond. lever-magazine prob. diff.2.43.19.42.82.82.82.31.31.42.6-3.12.8-1.7-1.4-2.1-1.3-1.30.50.80.8-0.2-0.5-0.2-1.90.20.20.61.2
Pavlov. Cond. response bias1.82.46.62.42.52.52.11.41.52.2-2.62.3-1.6-1.4-1.8-1.3-1.30.81.01.00.1-0.20.5-1.4-0.30.8-0.10.6
Time in closed arm before self-admin0.20.30.9-0.2-1.0-0.6-0.6-0.4-0.1-0.20.0-0.00.30.80.2-0.1-0.1-0.9-0.9-0.90.3-0.4-0.60.30.6-0.60.10.3
Time in closed arm after self-admin0.10.10.3-0.30.0-0.2-0.3-0.3-0.2-0.3-0.0-0.40.60.40.50.10.1-0.4-0.3-0.3-0.4-0.10.3-0.20.10.1-0.1-0.2
Time in open arm before self-admin0.70.82.5-1.4-0.6-1.0-0.8-0.4-0.8-1.41.6-1.60.40.01.20.80.80.30.50.5-0.20.71.00.7-0.70.5-0.6-1.2
Time in open arm after self-admin0.60.71.80.10.30.30.50.80.8-0.20.4-0.3-1.0-0.9-0.2-0.5-0.51.21.21.20.31.31.00.7-1.11.2-0.8-1.0
Bone: periosteal estimation1.12.34.9-1.00.1-0.7-1.2-2.0-1.8-0.90.6-0.81.82.01.51.61.6-2.2-2.1-2.1-2.0-1.90.1-1.42.2-0.30.61.4
Bone: periosteal perimeter0.30.61.4-0.40.0-0.3-0.7-0.9-0.8-0.40.3-0.30.81.10.80.70.7-1.2-1.2-1.2-1.0-1.00.4-0.61.10.2-0.10.5
Bone: post-yield work3.75.09.4-1.4-0.9-1.5-2.1-2.9-2.6-1.20.8-0.72.72.81.82.62.6-3.0-3.1-3.1-1.7-2.9-1.3-1.83.1-1.82.02.3
Progressive ratio test 1 active lever presses0.90.91.4-1.2-0.9-1.1-1.1-1.1-0.9-1.11.1-1.21.01.21.20.90.9-1.1-1.1-1.1-1.0-0.41.00.40.60.6-0.6-0.3
Progressive ratio test 1 breakpoint0.80.81.5-1.2-1.1-1.1-1.1-0.9-0.7-1.11.2-1.20.81.01.10.70.7-0.9-0.9-0.9-0.5-0.10.90.70.40.6-0.8-0.5
Progressive ratio test 1 inactive lever presses0.60.72.90.51.30.70.4-0.5-0.70.6-0.70.60.70.2-0.20.70.7-0.6-0.6-0.6-1.7-1.2-0.1-1.61.0-0.21.11.2
Progressive ratio test 2 active lever presses1.21.32.6-1.1-1.1-1.1-1.3-1.4-1.2-1.01.0-1.01.21.51.11.21.2-1.6-1.5-1.5-1.3-1.00.80.31.10.2-0.20.2
Progressive ratio test 2 breakpoint1.61.83.0-1.5-1.3-1.4-1.5-1.6-1.3-1.51.5-1.51.31.71.51.31.3-1.7-1.6-1.6-1.4-0.81.30.61.00.6-0.6-0.2
Progressive ratio test 2 inactive lever presses1.31.56.1-0.50.4-0.2-0.7-1.4-1.4-0.40.4-0.31.31.40.91.41.4-1.7-1.7-1.7-2.5-1.61.1-1.11.60.80.10.7
Incentive Sensitization - Responses0.30.31.2-0.10.0-0.1-0.2-0.6-0.6-0.0-0.10.00.50.70.20.60.6-1.0-0.9-0.9-1.1-0.80.1-0.50.9-0.00.50.6
Incentive Sensitization - Breakpoint0.60.61.7-0.2-0.0-0.2-0.4-0.9-0.9-0.20.0-0.10.81.00.40.80.8-1.3-1.2-1.2-1.3-1.10.1-0.61.1-0.10.60.8
Sum of active levers in priming session hrs 5-61.01.02.41.00.70.91.21.51.40.9-0.70.7-1.5-1.1-1.0-1.3-1.31.11.01.00.81.10.50.4-0.80.1-0.7-0.4
Progressive ratio0.30.30.7-0.1-0.5-0.3-0.3-0.4-0.50.10.00.20.40.4-0.10.70.7-0.6-0.6-0.6-0.2-0.8-0.8-0.20.8-0.80.80.9
Food seeking constrained by brief footshock0.10.10.4-0.3-0.3-0.1-0.10.20.2-0.10.4-0.3-0.2-0.5-0.00.10.10.60.50.50.10.30.40.6-0.50.5-0.5-0.5
Seeking ratio, punishment vs. effort0.30.41.5-0.10.60.30.20.40.2-0.10.2-0.4-0.3-0.60.2-0.3-0.30.90.80.8-0.20.61.20.2-0.91.2-0.9-0.9
Retroperitoneal fat weight3.611.821.0-3.9-2.6-3.6-4.0-4.3-4.6-3.53.1-3.34.64.14.04.14.1-4.0-4.1-4.1-2.7-2.7-0.5-0.83.4-1.21.31.3
Reaction time number correct0.60.93.50.7-0.30.40.41.21.10.6-0.71.0-0.9-1.0-0.9-1.0-1.01.01.01.01.90.8-1.50.6-1.0-0.80.2-0.5
Reaction time mean minus median0.91.22.51.2-0.50.50.81.51.61.1-0.71.2-1.3-0.9-1.5-1.4-1.41.00.90.91.60.8-1.30.9-0.8-0.70.1-0.0
Reaction time mean minus median AUC1.62.15.11.2-0.60.61.02.02.21.0-0.61.0-1.8-1.4-1.6-2.1-2.11.71.51.52.31.6-0.81.7-1.6-0.1-0.8-0.9
Reaction time num false alarms0.30.41.7-0.60.3-0.2-0.10.1-0.0-0.70.5-1.0-0.0-0.10.70.10.10.30.40.4-0.10.81.30.3-0.61.1-1.1-0.9
Reaction time num false alarms AUC0.30.51.5-0.30.50.10.40.50.3-0.40.4-0.8-0.3-0.50.3-0.1-0.10.70.80.80.51.21.20.3-0.91.1-1.0-0.9
Reaction time trials correct on left0.60.93.50.7-0.30.40.41.21.10.6-0.71.0-0.9-1.0-0.9-1.0-1.01.01.01.01.90.8-1.50.6-1.0-0.80.2-0.5
Reaction time trials on left0.71.04.10.7-0.30.40.41.31.30.6-0.71.0-1.0-1.1-0.9-1.1-1.11.11.11.12.00.9-1.50.6-1.1-0.70.1-0.5
Reaction time mean0.70.93.10.9-0.70.30.51.51.50.8-0.50.8-1.3-0.7-1.2-1.2-1.20.90.80.81.80.7-0.21.4-0.80.1-0.8-0.3
Reaction time mean AUC0.50.72.40.7-0.80.10.31.31.30.5-0.30.6-1.1-0.4-1.0-1.0-1.00.70.60.61.60.60.01.5-0.60.2-0.9-0.4
Median of all reaction times0.30.41.70.9-0.30.30.51.11.00.8-0.60.8-0.9-0.4-1.0-0.7-0.70.60.50.51.30.2-0.10.7-0.30.0-0.40.1
Reaction time omissions0.50.63.90.3-0.5-0.00.41.11.00.2-0.20.2-0.8-0.6-0.6-1.1-1.10.90.70.72.01.3-0.41.0-0.9-0.2-0.4-0.6
Reaction time false alarm rate0.40.63.5-0.80.7-0.2-0.1-0.5-0.7-0.80.8-1.30.50.41.00.60.6-0.2-0.1-0.1-1.00.41.9-0.20.01.4-0.8-0.4
Reaction time premature initiation rate1.11.56.10.81.40.80.8-0.8-0.81.1-1.01.20.6-0.1-0.70.60.6-0.9-0.6-0.6-1.5-1.3-1.5-2.11.4-1.62.52.2
Reaction time premature initiations0.91.34.41.41.31.21.30.40.31.6-1.51.7-0.5-1.0-1.4-0.4-0.40.10.50.5-0.1-0.3-1.9-1.50.3-1.52.11.5
Std. dev. reaction times1.01.44.20.7-0.90.10.51.71.70.5-0.10.5-1.5-0.9-1.1-1.6-1.61.31.21.22.11.5-0.21.8-1.30.2-1.0-0.9
Reaction time trials completed0.71.04.10.7-0.30.40.41.31.30.6-0.71.0-1.0-1.1-0.9-1.1-1.11.11.11.12.00.9-1.50.6-1.1-0.70.1-0.5
Reaction time trials AUC0.60.83.50.6-0.30.30.31.21.20.5-0.60.9-0.9-0.9-0.8-1.1-1.11.00.90.91.90.8-1.40.6-1.0-0.70.1-0.6
Run reversals in cocaine runway, females0.90.82.3-0.10.4-0.1-0.2-1.1-1.30.1-0.20.21.20.60.21.21.2-0.8-0.8-0.8-1.0-1.3-0.9-1.31.1-0.81.51.3
Run reversals in cocaine runway, males1.21.13.7-1.6-1.0-1.3-1.2-0.6-0.5-1.61.6-1.90.81.11.60.80.8-0.5-0.6-0.6-0.30.41.40.80.11.1-0.9-0.9
Latency to leave start box in cocaine runway2.62.85.1-1.3-1.2-1.5-1.7-2.1-2.1-1.10.8-0.92.22.11.42.22.2-2.2-2.3-2.3-1.2-1.8-0.9-0.72.0-1.11.41.2
Latency to leave start box in cocaine runway, F0.60.61.4-0.30.0-0.2-0.4-1.1-0.8-0.0-0.1-0.21.00.90.50.90.9-1.2-1.1-1.1-1.1-1.0-0.1-0.81.1-0.20.80.8
Latency to leave start box in cocaine runway, M3.53.48.3-2.2-2.9-2.7-2.5-1.9-1.8-2.22.0-1.81.92.21.82.12.1-1.8-2.0-2.00.5-0.8-1.31.11.3-1.50.30.2
Std. dev. time between licks in bursts0.20.20.8-0.8-0.3-0.5-0.4-0.1-0.6-0.50.8-0.80.20.10.60.60.6-0.20.00.0-0.9-0.00.80.40.00.3-0.4-0.3
Total sessions with >9 infusions1.31.42.9-0.9-1.2-1.1-1.3-1.6-1.6-0.70.5-0.41.71.40.71.51.5-1.5-1.4-1.4-0.8-1.6-0.7-0.11.3-0.70.70.9
Short access day 1 total inactive lever presses1.21.32.7-1.0-0.8-1.0-1.2-1.5-1.5-0.90.7-0.71.61.41.01.51.5-1.4-1.4-1.4-1.0-1.3-0.1-0.31.2-1.00.40.6
Short access day 10 total inactive lever presses0.80.92.1-1.4-1.2-1.3-1.3-1.0-1.2-1.31.4-1.21.00.81.11.41.4-0.6-0.6-0.6-0.2-0.40.00.60.30.5-0.5-0.4
Short access day 1 total infusions0.40.51.0-0.5-0.9-0.8-0.8-0.8-0.8-0.50.4-0.21.00.80.30.80.8-0.9-0.8-0.8-0.2-0.9-0.50.20.7-0.90.20.5
Short access day 10 total infusions2.73.07.3-0.6-0.5-0.7-1.1-2.1-2.3-0.20.10.22.21.80.52.42.4-2.2-2.1-2.1-2.1-2.7-1.2-1.42.3-1.51.72.0
Short access total infusions0.91.02.8-0.4-0.5-0.6-0.8-1.2-1.3-0.20.10.11.41.00.21.41.4-1.3-1.2-1.2-1.2-1.7-0.8-0.61.3-1.10.91.2
Short access day 1 locomotion0.60.61.80.30.80.40.2-0.5-0.70.5-0.70.60.90.4-0.20.80.8-0.8-0.7-0.7-1.3-1.2-0.1-1.31.0-0.80.91.2
Short access day 10 total locomotion1.51.75.10.20.50.1-0.3-1.2-1.50.4-0.60.71.30.9-0.11.61.6-1.3-1.4-1.4-2.0-2.3-0.9-1.71.8-1.41.51.9
Short access total locomotion1.61.75.20.50.90.50.1-1.0-1.30.7-1.01.01.30.7-0.31.51.5-1.3-1.2-1.2-2.0-2.3-0.6-2.01.8-1.11.52.1
One hour access (0.3 mA shock)2.22.54.8-1.7-0.9-1.4-1.7-1.9-1.8-1.61.6-1.71.72.01.91.81.8-1.9-1.8-1.8-2.2-1.21.90.21.31.0-0.8-0.2
Compulsive drug intake2.02.04.91.10.91.11.51.81.51.0-0.70.7-1.6-2.0-1.3-1.5-1.52.22.22.21.31.60.20.5-1.80.6-0.4-0.8
One hour access (shock baseline)2.83.36.1-2.1-1.7-2.0-2.2-2.1-1.7-2.12.1-2.11.72.52.21.71.7-2.3-2.3-2.3-1.8-1.01.60.71.50.8-1.1-0.3
Social response proportion0.40.40.9-0.9-0.5-0.8-0.7-0.6-0.7-0.90.6-0.80.50.90.90.70.7-0.7-0.7-0.70.40.0-0.10.10.5-0.3-0.0-0.1
Social responses0.40.51.6-0.50.1-0.2-0.10.20.2-0.80.4-1.1-0.5-0.00.7-0.5-0.50.40.30.30.41.21.20.6-0.71.1-0.8-1.2
Social time1.01.32.80.3-0.20.30.51.51.30.2-0.10.1-1.3-1.2-0.5-1.3-1.31.61.51.51.61.70.21.3-1.70.4-0.9-1.5
Soleus weight1.13.28.1-2.5-1.5-2.0-2.2-1.4-1.0-2.62.5-2.90.91.72.70.90.9-1.1-1.0-1.0-1.00.12.51.30.12.3-2.4-1.6
Bone: stiffness0.20.41.50.20.90.40.1-0.7-0.40.2-0.40.30.40.50.20.40.4-0.9-0.9-0.9-0.4-0.7-0.1-1.21.0-0.20.70.9
Tibialis anterior weight3.913.530.55.54.75.25.33.73.15.5-5.45.4-2.8-4.0-5.3-2.6-2.63.32.72.71.90.6-2.0-2.8-1.3-0.92.41.7
Time to tail flick, vehicle, before self-admin1.01.03.40.50.10.1-0.1-0.6-0.70.6-1.01.00.80.6-0.50.80.8-1.0-0.9-0.9-0.2-1.5-1.8-1.21.2-1.61.61.7
Time to tail flick, vehicle, after self-admin0.70.84.80.80.20.50.40.1-0.01.0-1.01.30.1-0.4-1.00.10.10.10.10.10.7-0.8-2.0-0.70.2-2.21.41.1
Time to tail flick, test, before self-admin0.90.92.0-0.20.1-0.2-0.5-1.4-1.1-0.2-0.10.11.40.80.41.11.1-1.1-1.0-1.0-0.8-1.3-1.0-1.31.1-0.71.41.1
Time to tail flick, test, after self-admin0.20.21.0-0.5-0.6-0.5-0.3-0.10.2-0.60.7-0.7-0.00.10.5-0.2-0.20.00.10.1-0.00.50.40.7-0.3-1.0-0.4-0.6
Delta time to tail flick, vehicle, before/after SA0.20.10.40.20.20.30.30.40.40.3-0.00.1-0.4-0.5-0.3-0.5-0.50.50.60.60.40.50.20.2-0.6-0.1-0.2-0.4
Delta time to tail flick, test, before/after SA1.71.53.20.50.60.81.01.61.60.4-0.0-0.1-1.8-1.3-0.5-1.6-1.61.51.51.50.21.71.61.1-1.50.3-1.5-1.4
Tibia length0.41.03.91.31.21.10.9-0.10.11.4-1.41.5-0.2-0.5-1.0-0.4-0.4-0.2-0.2-0.2-0.4-0.7-1.4-1.60.7-1.12.01.4
Ambulatory time before self-admin0.91.02.31.40.81.21.10.81.31.3-1.41.3-1.3-0.8-1.2-1.5-1.50.60.60.60.10.3-0.6-0.4-0.40.10.80.3
Ambulatory time after self-admin0.20.31.10.30.30.2-0.0-0.8-0.10.3-0.60.40.20.50.10.00.0-0.8-0.7-0.7-1.1-0.8-0.1-0.70.60.00.50.5
Bone: tissue strength0.30.30.7-0.7-0.4-0.5-0.6-0.4-0.2-0.70.8-0.80.30.50.80.30.3-0.3-0.4-0.4-0.30.10.80.40.00.7-0.7-0.5
Total heroin consumption3.23.76.32.11.41.92.32.52.22.0-1.51.9-2.4-2.5-2.3-2.2-2.22.42.42.42.01.8-1.20.0-1.7-0.30.4-0.2
Bone: trabecular number0.40.61.70.40.50.30.1-0.5-0.60.4-0.80.50.70.5-0.20.90.9-0.8-0.8-0.8-0.4-1.1-0.6-1.11.1-0.71.21.3
Bone: trabecular spacing1.31.83.50.40.20.60.61.31.60.20.20.0-1.7-1.4-0.5-1.7-1.71.61.61.61.01.61.51.4-1.91.7-1.8-1.9
Bone: trabecular thickness0.70.81.8-0.9-0.2-0.7-1.0-1.1-0.9-1.00.8-1.01.01.21.30.70.7-1.2-1.3-1.3-1.1-0.50.6-0.40.90.50.00.2
Bone: trabecular tissue density1.31.84.9-2.0-1.5-1.7-1.7-0.9-0.6-2.02.1-2.20.71.22.00.20.2-0.7-0.7-0.7-1.30.51.31.3-0.11.3-1.5-1.3
Water consumed over 24 hours0.10.10.90.11.00.40.5-0.0-0.10.1-0.1-0.2-0.4-0.40.10.10.1-0.00.30.3-0.10.40.6-0.5-0.10.10.10.0
Number of responses in last shaping day0.10.10.40.30.40.40.50.40.30.3-0.30.1-0.3-0.6-0.4-0.2-0.20.60.60.6-0.00.40.50.1-0.50.5-0.2-0.2