Hub : Genes

LOC120094203

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression LOC120094203 0.1 0.07 5.2e-06 0.09 0.08 0.07 0.08 1.1e-05 4.6e-05 2.0e-04 4.2e-05
2 NAcc gene expression LOC120094203 0.18 0.09 0.0e+00 0.18 0.21 0.21 0.21 2.9e-26 6.6e-31 8.5e-31 1.6e-30
3 RMTg gene expression LOC120094203 0.35 0.2 5.3e-06 0.2 0.22 0.19 0.23 4.5e-06 1.5e-06 7.6e-06 7.7e-07
4 Brain gene expression LOC120094203 0.21 0.11 0.0e+00 0.28 0.29 0.28 0.28 7.0e-26 7.7e-27 5.6e-26 5.3e-26
5 IC gene expression LOC120094203 0.14 0.09 3.6e-05 0.1 0.1 0.1 0.12 7.8e-05 4.3e-05 5.3e-05 1.4e-05
6 pVTA gene expression LOC120094203 0.25 0.11 0.0e+00 0.3 0.31 0.32 0.31 2.7e-24 8.7e-26 7.9e-26 1.1e-25
7 LHb gene expression LOC120094203 0.2 0.13 6.9e-04 0.09 0.07 0.06 0.07 4.5e-03 7.7e-03 1.2e-02 8.1e-03
8 PL gene expression LOC120094203 0.05 0.03 3.4e-07 0.06 0.06 0.06 0.06 2.9e-07 1.4e-07 8.4e-07 2.2e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.20.40.60.70.50.70.60.40.60.80.7
Area under the delay curve0.00.00.10.2-0.30.30.0-0.2-0.00.20.3
BMI with tail7.024.226.3-4.8-5.1-4.8-5.0-5.1-5.0-4.8-4.7
BMI without tail2.68.08.8-2.9-2.8-3.0-2.9-2.5-2.9-2.8-2.8
Body weight5.021.826.1-4.5-5.1-4.5-4.7-4.8-4.9-4.5-4.3
Weight adjusted by age4.67.09.1-3.0-2.4-2.6-2.7-2.4-2.4-2.8-2.8
Bone surface0.10.20.2-0.4-0.4-0.4-0.4-0.4-0.5-0.4-0.4
Bone volume0.00.00.1-0.1-0.2-0.1-0.2-0.3-0.2-0.1-0.1
Breakpoint value in progressive ratio session0.80.91.1-1.0-1.0-1.0-0.9-0.9-1.1-1.0-0.8
Number of licking bursts1.32.12.71.31.61.31.51.61.51.41.3
Context. condit. distance diff. score0.91.11.71.20.81.21.00.80.91.31.1
Locomotion velocity, session 11.41.52.1-1.4-0.7-1.4-1.2-0.8-1.0-1.5-1.4
Locomotion distance, session 10.30.40.80.50.80.40.60.90.70.30.5
Locomotion velocity, session 20.10.20.4-0.5-0.2-0.4-0.4-0.2-0.3-0.6-0.5
Locomotion distance, session 20.20.20.5-0.5-0.2-0.6-0.4-0.1-0.4-0.7-0.5
Locomotion velocity, session 30.20.30.80.10.90.10.40.90.60.00.0
Locomotion distance, session 32.42.63.31.51.71.51.61.81.81.41.5
Stereotopy head waving bouts, day 30.50.60.7-0.9-0.7-0.8-0.8-0.7-0.7-0.8-0.8
Stereotopy head waving duration, day 30.60.80.9-1.0-0.7-1.0-0.9-0.7-0.8-0.9-1.0
Locomotion velocity, session 71.92.12.41.41.51.41.51.51.51.41.4
Locomotion distance, session 72.02.63.31.51.81.41.61.81.71.51.4
Stereotopy head waving bouts, day 70.91.01.3-1.2-0.8-1.1-1.0-0.8-0.8-1.1-1.1
Stereotopy head waving duration, day 70.50.61.0-1.0-0.5-0.9-0.8-0.5-0.5-0.9-1.0
Locomotion velocity, session 80.30.40.6-0.6-0.3-0.7-0.6-0.4-0.7-0.7-0.8
Locomotion distance, session 80.60.81.10.91.00.80.91.00.90.90.9
Degree of sensitization distance0.20.20.30.40.50.40.40.40.40.60.3
Degree of sensitization stereotypy0.50.50.7-0.8-0.5-0.8-0.7-0.6-0.5-0.8-0.8
Conditioned locomotion0.10.10.20.4-0.20.40.1-0.3-0.10.20.4
Cocaine response after cond. corrected2.83.34.3-1.9-1.6-1.9-1.8-1.5-1.7-2.1-1.9
Cocaine response after cond. not corrected1.61.92.7-1.5-1.2-1.5-1.3-1.1-1.3-1.7-1.4
Cocaine response before conditioning0.81.01.31.10.81.11.00.80.91.01.1
Saline control response0.30.40.90.30.90.30.50.90.80.40.3
Bone: connectivity density0.71.11.21.01.11.01.01.11.11.11.0
Bone: cortical apparent density1.21.72.21.21.41.21.31.51.31.31.2
Bone: cortical area0.10.10.10.20.30.20.30.30.40.30.3
Bone: cortical porosity1.11.21.51.11.01.11.21.11.01.11.2
Bone: cortical porosity1.31.42.01.30.91.31.21.01.01.21.4
Bone: cortical thickness1.62.62.71.61.61.61.71.61.61.61.6
Bone: cortical thickness0.60.71.00.70.90.70.91.00.80.80.8
Bone: cortical tissue density1.21.62.01.11.31.11.31.41.31.31.2
Condit. Reinf. active minus inactive responses0.10.10.30.1-0.60.1-0.1-0.5-0.4-0.00.2
Condit. Reinf. active-inactive response ratio0.30.30.70.70.00.70.50.20.30.70.8
Condit. Reinf. active responses0.40.50.8-0.6-0.9-0.6-0.7-0.8-0.9-0.7-0.5
Condit. Reinf. inactive responses0.70.91.3-1.0-0.6-1.1-0.9-0.7-0.9-1.1-1.1
Incentive salience index mean0.10.20.6-0.0-0.8-0.0-0.3-0.7-0.6-0.10.1
Condit. Reinf. lever presses0.10.10.30.1-0.50.1-0.1-0.5-0.3-0.00.1
Condit. Reinf. active minus inactive responses3.24.24.8-1.9-2.2-1.9-2.1-2.1-2.1-2.2-1.9
Condit. Reinf. active-inactive response ratio1.11.31.5-1.0-1.2-1.0-1.1-1.2-1.2-1.2-1.0
Condit. Reinf. active responses2.02.84.0-1.5-2.0-1.5-1.7-1.7-1.7-1.7-1.4
Condit. Reinf. inactive responses0.00.10.3-0.1-0.5-0.1-0.2-0.3-0.2-0.30.0
Condit. Reinf. lever presses0.40.60.80.90.60.90.80.70.70.70.9
Condit. Reinf. lever reinforcers received1.31.82.9-1.1-1.7-1.2-1.4-1.5-1.4-1.4-1.1
Conditioned reinforcement - actives0.00.00.0-0.00.0-0.1-0.00.0-0.1-0.2-0.1
Conditioned reinforcement - inactives0.30.40.90.50.80.50.60.90.70.40.5
Conditioned locomotion0.30.40.70.80.20.70.60.20.50.70.8
Patch foraging indifference point 0 sec0.20.40.7-0.8-0.4-0.8-0.6-0.3-0.4-0.8-0.8
Patch foraging indifference point AUC0.10.10.30.2-0.4-0.0-0.1-0.1-0.5-0.40.2
Delay disc. indifference point, 0s delay0.30.40.60.60.40.80.60.40.50.70.8
Delay disc. indifference point, 16s delay0.30.30.70.80.10.90.5-0.00.30.60.8
Delay disc. indifference point, 2s delay0.20.20.40.30.40.40.50.60.40.40.5
Delay disc. indifference point, 24s delay0.30.30.60.70.40.80.50.30.50.60.6
Delay disc. indifference point, 4s delay0.20.20.50.6-0.00.60.40.10.30.50.7
Delay disc. indifference point, 8s delay0.10.20.4-0.3-0.6-0.2-0.4-0.6-0.3-0.1-0.3
Indifference point function ln k0.40.71.2-1.1-0.6-1.0-0.9-0.7-0.5-0.6-1.0
Indifference point function log k0.40.71.2-1.1-0.6-1.0-0.9-0.7-0.5-0.6-1.0
Patch foraging total patch changes 0 sec0.30.60.9-0.9-0.4-0.9-0.7-0.3-0.5-0.9-0.9
Patch foraging total patch changes 12 sec0.10.10.20.40.30.30.30.40.1-0.10.3
Patch foraging total patch changes 18 sec0.00.10.3-0.1-0.1-0.1-0.10.1-0.1-0.6-0.1
Patch foraging total patch changes 24 sec0.10.20.6-0.3-0.1-0.5-0.3-0.0-0.5-0.8-0.5
Patch foraging total patch changes 6 sec0.30.40.9-0.5-0.5-0.6-0.6-0.4-0.6-1.0-0.6
Patch foraging time to switch 0 sec1.42.83.61.91.51.91.61.31.81.71.7
Patch foraging water rate 0 sec1.83.84.9-2.0-1.8-2.1-1.9-1.6-1.9-2.2-2.0
Patch foraging water rate 12 sec3.57.29.4-3.1-2.3-3.0-2.6-2.0-2.6-3.0-2.8
Patch foraging water rate 18 sec0.50.81.1-1.0-0.7-1.0-0.8-0.6-0.8-0.9-0.9
Patch foraging water rate 24 sec0.40.50.9-0.9-0.5-0.9-0.5-0.2-0.7-0.9-0.7
Patch foraging water rate 6 sec1.42.02.4-1.5-1.3-1.5-1.4-1.1-1.5-1.5-1.4
Seeking ratio, delayed vs. immediate footshock0.60.81.0-1.0-1.0-0.8-0.9-0.9-0.7-0.7-0.9
Distance traveled before self-admin0.10.10.30.10.40.30.20.30.40.50.1
Distance traveled after self-admin0.91.11.9-1.4-0.7-1.3-1.1-0.8-0.6-0.9-1.4
Extensor digitorum longus weight9.436.940.2-6.0-6.2-6.0-6.1-6.2-6.3-5.9-5.9
Bone: elastic displacement0.50.60.9-0.6-0.9-0.6-0.8-0.9-0.9-0.7-0.6
Bone: elastic work0.10.20.5-0.2-0.7-0.2-0.3-0.6-0.5-0.1-0.0
Bone: endosteal estimation2.14.64.8-2.2-2.0-2.2-2.2-2.1-2.1-2.2-2.2
Bone: endosteal perimeter3.57.48.3-2.6-2.8-2.6-2.8-2.9-2.7-2.7-2.6
Epididymis fat weight0.00.10.20.00.2-0.00.10.40.3-0.20.1
Delta time in closed arm before/after self-admin0.90.81.31.00.81.00.80.61.10.90.9
Delta time in open arm before/after self-admin0.60.61.30.61.00.60.81.10.70.40.6
Diff in mean of infusions in LGA sessions1.11.32.5-0.8-1.6-0.8-1.1-1.6-1.2-1.2-0.7
Delay discount exponential model param0.00.00.1-0.10.3-0.20.00.30.1-0.1-0.1
Extinction: sum of active levers before priming0.40.41.0-1.0-0.3-0.8-0.6-0.3-0.4-0.6-0.9
Active lever presses in extinction session 60.60.60.8-0.9-0.8-0.8-0.8-0.8-0.6-0.8-0.8
Bone: final force0.30.40.6-0.7-0.8-0.7-0.7-0.7-0.6-0.6-0.6
Bone: final moment0.00.10.1-0.3-0.4-0.2-0.2-0.3-0.2-0.1-0.2
Food consumed during 24 hour testing period0.50.71.2-1.0-0.5-1.0-0.9-0.5-0.6-0.8-1.1
Glucose0.71.11.5-1.2-0.8-1.2-1.0-0.7-1.0-1.2-1.1
Heart weight1.11.72.7-1.1-1.6-1.0-1.3-1.6-1.4-1.0-1.1
Delay discount hyperbolic model param0.00.10.1-0.20.2-0.3-0.10.1-0.1-0.3-0.3
Intermittent access intake day 1-15 change0.51.11.70.91.30.90.91.01.31.00.7
Intermittent access intake escalation0.30.61.00.71.00.70.70.71.00.80.6
Intermittent access intake escalation 20.00.00.10.00.20.1-0.0-0.10.20.1-0.1
Intermitt. access day 1 inactive lever presses0.93.44.22.01.82.01.71.62.01.81.8
Intermitt. access day 15 inactive lever presses0.00.10.4-0.0-0.20.1-0.3-0.7-0.00.0-0.2
Intermitt. access escalation Index0.40.51.4-0.5-0.8-0.4-0.8-1.2-0.5-0.3-0.6
Intermittent access day 1 total infusions1.01.52.21.21.41.11.41.51.01.01.2
Intermittent access day 15 total infusions1.52.22.71.51.61.41.61.61.41.31.5
Intermittent access terminal intake (last 3 days)0.91.21.71.11.11.01.21.30.80.91.2
Intermittent access total infusions0.70.91.90.71.10.71.01.40.80.50.8
Intermittent access day 1 locomotion3.34.15.22.32.12.12.11.91.91.72.0
Intermittent access day 15 total locomotion1.32.33.11.81.51.61.51.31.61.41.5
Intermittent access total locomotion0.10.10.20.40.40.30.40.40.40.00.3
Intermittent access standard deviation0.20.30.80.40.90.40.60.70.50.60.4
Left kidney weight1.56.97.6-2.6-2.5-2.7-2.7-2.6-2.5-2.6-2.7
Right kidney weight1.98.810.0-3.1-2.7-3.2-3.0-2.6-2.8-3.1-3.1
Cocaine induced anxiety0.10.20.30.50.10.40.40.30.30.40.5
Post-drug Anxiety2.72.93.21.71.71.61.71.81.71.71.6
Baseline Anxiety1.01.22.10.81.40.81.01.41.30.80.7
Tail length0.10.21.20.00.5-0.10.41.10.3-0.00.2
Length with tail0.52.22.8-1.6-1.5-1.7-1.4-1.0-1.5-1.7-1.4
Length without tail3.912.615.2-3.3-3.9-3.3-3.5-3.8-3.7-3.5-3.2
Times rat made contact with spout0.30.40.60.50.70.50.60.60.60.80.5
Lifetime Intake0.50.61.60.61.00.60.91.30.60.30.7
Liver weight, left4.06.57.7-2.5-2.4-2.6-2.6-2.5-2.4-2.8-2.6
Liver weight, right0.91.62.4-1.3-1.1-1.4-1.3-1.0-1.1-1.5-1.3
Locomotor activity6.510.111.3-3.4-3.2-3.2-3.1-3.1-3.2-3.0-3.1
Locomotor testing distance3.76.78.1-2.8-2.5-2.6-2.6-2.5-2.5-2.5-2.6
Locomotor testing rearing1.73.44.0-2.0-1.9-1.8-1.9-1.8-1.8-1.7-1.8
Locomotion in novel chamber0.20.20.40.30.40.30.50.50.50.60.5
Locomotion in novel chamber post-restriction0.30.61.10.80.41.00.60.30.71.10.8
Fecal boli incidents, locomotor time 10.10.10.30.40.20.20.40.30.30.50.4
Change in fecal boli incidents, locomotor task0.20.20.4-0.50.0-0.4-0.4-0.2-0.1-0.4-0.6
Time >=10cm from walls, locomotor time 10.20.20.5-0.4-0.7-0.4-0.5-0.4-0.5-0.3-0.3
Bouts of movement, locomotor time 10.20.20.4-0.6-0.4-0.5-0.4-0.3-0.2-0.4-0.4
Total resting periods, locomotor time 10.10.10.3-0.5-0.2-0.4-0.3-0.2-0.1-0.4-0.3
Rest time, locomotor task time 10.00.00.10.30.00.30.10.30.2-0.10.2
Distance moved, locomotor task time 10.10.10.20.40.40.40.40.30.10.20.3
Vertical activity count, locomotor time 10.00.10.20.30.20.30.30.00.00.50.4
Time >=10cm from walls, locomotor time 20.00.00.10.0-0.3-0.0-0.2-0.2-0.2-0.3-0.1
Bouts of movement, locomotor time 20.81.21.7-1.3-1.0-1.2-1.1-0.8-0.9-1.3-1.1
Total resting periods, locomotor time 20.81.32.0-1.4-1.0-1.3-1.1-0.8-0.9-1.4-1.2
Rest time, locomotor task time 20.30.40.90.50.70.70.60.71.00.40.6
Distance moved, locomotor task time 20.00.00.00.10.10.0-0.0-0.0-0.2-0.1-0.1
Vertical activity count, locomotor time 20.50.71.00.81.00.80.91.00.60.80.8
Light reinforcement 13.07.59.4-2.6-3.1-2.5-2.9-2.9-2.7-2.6-2.6
Light reinforcement 20.10.10.30.20.40.30.40.60.30.30.3
Bone: marrow area2.14.64.8-2.2-2.0-2.2-2.2-2.1-2.1-2.2-2.2
Bone: maximum diameter2.03.74.1-2.0-1.8-2.0-1.9-1.8-1.8-2.0-2.0
Bone: maximum force0.30.60.7-0.7-0.9-0.7-0.7-0.8-0.8-0.6-0.6
Bone: maximum moment0.10.10.2-0.3-0.5-0.3-0.3-0.4-0.4-0.2-0.2
Mean time between licks in bursts0.10.20.30.60.30.60.40.10.30.60.5
Mean num. licks in bursts0.50.81.1-0.9-0.9-0.9-1.0-1.0-1.0-0.8-0.9
Cd content in liver0.91.01.71.10.71.11.00.70.91.31.2
Co content in liver0.80.91.41.20.41.20.90.50.61.21.2
Cu content in liver0.00.00.10.1-0.30.0-0.1-0.2-0.1-0.00.1
Fe content in liver0.20.20.4-0.6-0.1-0.6-0.4-0.2-0.3-0.6-0.6
K content in liver2.12.02.5-1.4-1.5-1.4-1.4-1.4-1.5-1.6-1.3
Mg content in liver1.71.72.0-1.3-1.4-1.3-1.3-1.3-1.3-1.4-1.2
Mn content in liver0.00.00.00.1-0.10.10.0-0.1-0.00.10.1
Na content in liver7.58.010.1-2.9-2.7-2.9-2.8-2.6-2.8-3.2-2.9
Rb content in liver0.60.71.0-1.0-0.6-1.0-0.8-0.6-0.7-0.8-1.0
Se content in liver0.10.20.40.20.60.20.40.60.50.10.2
Sr content in liver0.00.00.10.30.10.30.20.20.10.00.3
Zn content in liver0.20.20.6-0.1-0.8-0.1-0.3-0.6-0.6-0.3-0.0
Bone: minimum diameter0.00.10.20.3-0.10.30.1-0.20.00.40.3
Time in familiar zone, hab. session 10.10.10.2-0.1-0.4-0.1-0.2-0.3-0.3-0.1-0.1
Time in novel zone, hab. session 10.30.30.50.40.70.40.50.70.70.40.4
Total zone transitions, hab. session 10.40.61.10.61.00.60.71.00.90.50.5
Total locomotion distance, hab. session 10.10.10.30.20.50.20.30.50.40.10.2
Locomotion velocity, hab. session 10.00.00.1-0.00.3-0.10.10.30.2-0.2-0.1
Time in familiar zone, hab. session 20.00.10.10.10.40.10.20.30.20.30.1
Time in novel zone, hab. session 20.00.00.10.20.20.20.20.20.20.20.3
Total zone transitions, hab. session 20.50.61.0-0.7-1.0-0.7-0.8-0.8-0.9-0.8-0.6
Total locomotion distance, hab. session 21.01.32.2-1.0-1.5-1.0-1.1-1.3-1.3-1.1-0.9
Locomotion velocity, hab. session 20.60.81.4-0.7-1.2-0.7-0.8-1.0-1.1-0.9-0.6
Novel to familiar place preference ratio1.11.21.9-1.0-1.3-1.0-1.1-1.4-1.1-0.9-1.0
Novelty place preference1.21.21.9-1.0-1.3-1.0-1.1-1.4-1.1-0.9-1.0
Time in novel zone, NPP test1.31.42.0-1.1-1.3-1.1-1.2-1.4-1.2-1.0-1.1
Total zone transitions, NPP test0.30.50.8-0.6-0.7-0.6-0.6-0.6-0.8-0.9-0.6
Total locomotion distance, NPP test0.60.81.3-0.9-0.8-0.9-0.9-0.7-1.0-1.1-0.9
Locomotion velocity, NPP test0.20.30.7-0.5-0.4-0.6-0.5-0.3-0.6-0.8-0.5
Intraocular pressure0.00.00.1-0.0-0.0-0.1-0.1-0.3-0.20.2-0.1
Delta distance traveled before/after self-admin1.81.92.4-1.5-1.2-1.6-1.4-1.2-1.2-1.4-1.5
Delta ambulatory time before/after self-admin0.70.91.2-1.1-0.8-1.1-1.0-0.7-0.8-1.0-1.1
Parametrial fat weight1.22.83.81.51.81.51.71.91.71.51.6
Pavlov. Cond. lever latency0.30.40.80.40.80.30.60.90.70.50.4
Pavlov. Cond. magazine entry latency0.40.51.20.9-0.50.90.5-0.3-0.10.71.1
Pavlov. Cond. change in total contacts0.20.20.60.1-0.80.2-0.2-0.7-0.5-0.10.2
Pavlov. Cond. index score0.20.30.70.7-0.20.80.4-0.10.10.60.8
Pavlov. Cond. latency score0.10.10.20.4-0.40.40.1-0.3-0.20.20.5
Pavlov. Cond. lever contacts0.20.20.5-0.1-0.7-0.0-0.4-0.7-0.5-0.2-0.1
Pavlov. Cond. magazine entry number0.60.81.7-1.20.1-1.1-0.8-0.1-0.3-1.0-1.3
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.40.3-0.3-0.10.20.0-0.3-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.20.40.5-0.40.50.2-0.3-0.20.30.6
Pavlov. Cond. response bias0.20.30.60.7-0.60.70.2-0.4-0.20.50.8
Pavlov. Cond. lever latency0.10.20.4-0.6-0.1-0.6-0.4-0.3-0.3-0.4-0.6
Pavlov. Cond. magazine entry latency3.44.14.32.11.92.12.12.02.01.92.1
Pavlov. Cond. change in total contacts0.40.60.90.90.60.90.80.70.70.70.9
Pavlov. Cond. index score0.81.01.31.10.81.11.00.90.91.01.2
Pavlov. Cond. latency score0.50.60.80.90.70.90.80.70.70.70.9
Pavlov. Cond. lever contacts0.10.20.40.60.20.50.40.30.30.40.6
Pavlov. Cond. magazine entry number3.44.14.4-2.1-2.0-2.0-2.1-2.0-2.0-1.9-2.1
Pavlov. Cond. intertrial magazine entries0.81.11.5-1.2-0.9-1.2-1.1-0.9-0.9-1.1-1.2
Pavlov. Cond. lever-magazine prob. diff.0.91.21.51.20.91.21.11.01.01.01.2
Pavlov. Cond. response bias1.11.52.31.40.81.41.31.01.01.21.5
Time in closed arm before self-admin0.10.10.20.3-0.00.30.3-0.1-0.20.40.5
Time in closed arm after self-admin0.30.30.70.60.50.60.60.30.50.90.6
Time in open arm before self-admin0.70.71.1-0.8-0.9-0.8-1.0-1.1-0.4-0.7-0.9
Time in open arm after self-admin0.10.10.4-0.2-0.1-0.3-0.3-0.1-0.0-0.6-0.4
Bone: periosteal estimation1.02.02.2-1.5-1.3-1.5-1.4-1.4-1.4-1.5-1.5
Bone: periosteal perimeter1.62.83.0-1.7-1.6-1.7-1.7-1.6-1.6-1.7-1.7
Bone: post-yield work0.10.20.2-0.5-0.4-0.4-0.4-0.4-0.4-0.3-0.4
Progressive ratio test 1 active lever presses0.50.61.10.71.00.60.91.10.70.40.7
Progressive ratio test 1 breakpoint0.60.71.20.81.00.70.91.10.70.50.8
Progressive ratio test 1 inactive lever presses4.15.99.32.32.92.22.53.12.61.62.2
Progressive ratio test 2 active lever presses0.00.00.2-0.10.0-0.1-0.10.0-0.1-0.4-0.1
Progressive ratio test 2 breakpoint0.00.00.2-0.10.0-0.1-0.00.1-0.0-0.4-0.1
Progressive ratio test 2 inactive lever presses0.40.71.10.90.90.80.91.00.70.40.9
Incentive Sensitization - Responses0.20.20.6-0.4-0.6-0.3-0.5-0.7-0.3-0.4-0.4
Incentive Sensitization - Breakpoint0.10.10.4-0.3-0.5-0.2-0.4-0.7-0.2-0.3-0.3
Sum of active levers in priming session hrs 5-60.10.10.2-0.5-0.0-0.4-0.20.20.1-0.3-0.4
Progressive ratio0.71.02.71.10.41.20.80.20.91.61.2
Food seeking constrained by brief footshock0.20.30.6-0.6-0.1-0.8-0.5-0.4-0.3-0.3-0.8
Seeking ratio, punishment vs. effort3.55.07.1-2.3-1.5-2.6-2.2-1.6-2.2-2.7-2.5
Retroperitoneal fat weight0.20.72.00.41.10.30.81.40.90.40.5
Reaction time number correct1.22.32.9-1.7-1.5-1.7-1.5-1.3-1.4-1.5-1.6
Reaction time mean minus median0.10.30.90.50.80.40.61.00.50.00.4
Reaction time mean minus median AUC0.51.22.80.81.40.71.11.71.10.50.8
Reaction time num false alarms0.50.81.20.71.10.80.91.01.00.80.7
Reaction time num false alarms AUC0.30.40.90.31.00.50.60.80.80.50.3
Reaction time trials correct on left1.22.32.9-1.7-1.5-1.7-1.5-1.3-1.4-1.5-1.6
Reaction time trials on left1.32.53.1-1.7-1.6-1.8-1.6-1.3-1.5-1.6-1.6
Reaction time mean2.23.54.81.82.11.82.02.21.71.61.8
Reaction time mean AUC1.72.73.91.51.91.51.82.01.51.31.6
Median of all reaction times3.85.46.22.32.42.32.52.52.12.22.4
Reaction time omissions0.10.20.4-0.5-0.1-0.3-0.4-0.2-0.4-0.6-0.5
Reaction time false alarm rate1.42.02.91.21.71.41.41.41.51.31.2
Reaction time premature initiation rate1.41.92.5-1.4-1.3-1.4-1.4-1.1-1.4-1.6-1.3
Reaction time premature initiations2.03.54.1-2.0-1.8-2.0-1.9-1.5-1.9-2.0-1.8
Std. dev. reaction times0.91.72.81.21.61.21.41.71.20.81.2
Reaction time trials completed1.32.53.1-1.7-1.6-1.8-1.6-1.3-1.5-1.6-1.6
Reaction time trials AUC1.12.12.6-1.6-1.4-1.6-1.5-1.2-1.4-1.4-1.5
Run reversals in cocaine runway, females0.10.10.20.20.5-0.00.10.20.30.10.0
Run reversals in cocaine runway, males0.10.10.2-0.3-0.1-0.4-0.3-0.4-0.2-0.2-0.4
Latency to leave start box in cocaine runway1.51.72.2-1.2-1.2-1.1-1.4-1.4-1.1-1.5-1.4
Latency to leave start box in cocaine runway, F0.30.40.8-0.6-0.3-0.5-0.7-0.6-0.4-0.9-0.8
Latency to leave start box in cocaine runway, M5.04.75.3-2.1-2.3-2.1-2.2-2.3-2.2-2.1-2.1
Std. dev. time between licks in bursts1.01.42.5-0.8-1.5-0.8-1.1-1.6-1.5-0.8-0.8
Total sessions with >9 infusions0.70.82.60.51.30.51.01.60.70.30.7
Short access day 1 total inactive lever presses1.01.31.91.01.41.11.11.31.30.90.9
Short access day 10 total inactive lever presses0.71.82.51.41.51.41.21.21.61.31.1
Short access day 1 total infusions0.40.51.00.61.00.60.70.90.80.50.5
Short access day 10 total infusions1.72.23.81.41.61.31.71.91.21.11.5
Short access total infusions1.11.43.11.01.40.91.31.81.00.71.1
Short access day 1 locomotion0.10.10.20.40.30.40.30.20.30.30.3
Short access day 10 total locomotion0.30.61.20.71.10.60.71.10.90.40.5
Short access total locomotion0.81.01.71.01.20.91.01.31.00.60.9
One hour access (0.3 mA shock)0.60.71.0-0.7-0.7-0.8-0.7-0.8-1.0-0.9-0.8
Compulsive drug intake1.51.72.4-1.5-1.0-1.6-1.2-0.8-1.4-1.4-1.4
One hour access (shock baseline)0.20.30.50.70.50.70.60.30.50.50.6
Social response proportion0.10.10.30.4-0.10.40.1-0.4-0.00.60.3
Social responses0.00.00.0-0.1-0.2-0.1-0.1-0.1-0.2-0.1-0.1
Social time0.10.10.50.00.50.10.20.50.70.3-0.0
Soleus weight17.852.454.6-7.3-7.3-7.2-7.3-7.2-7.4-7.1-7.1
Bone: stiffness0.40.71.1-1.1-0.4-1.0-0.8-0.4-0.6-0.9-1.0
Tibialis anterior weight14.248.150.8-7.1-6.7-7.1-7.0-6.7-6.9-6.9-7.0
Time to tail flick, vehicle, before self-admin0.00.00.10.20.00.20.20.10.30.20.3
Time to tail flick, vehicle, after self-admin0.91.22.21.11.11.10.90.71.31.50.9
Time to tail flick, test, before self-admin1.11.11.91.30.51.31.10.50.71.21.4
Time to tail flick, test, after self-admin3.33.44.01.92.01.81.81.81.91.91.7
Delta time to tail flick, vehicle, before/after SA1.11.01.51.01.11.00.91.01.11.20.8
Delta time to tail flick, test, before/after SA0.10.10.3-0.10.5-0.20.10.50.30.0-0.2
Tibia length0.00.10.20.40.00.40.30.00.20.40.5
Ambulatory time before self-admin0.20.40.70.40.70.50.60.80.50.70.5
Ambulatory time after self-admin0.30.40.8-0.9-0.3-0.8-0.6-0.2-0.3-0.6-0.8
Bone: tissue strength1.51.51.61.21.21.21.21.21.21.31.2
Total heroin consumption1.11.31.5-1.2-1.1-1.2-1.2-1.1-1.1-1.1-1.2
Bone: trabecular number0.91.41.91.31.01.31.21.01.11.41.3
Bone: trabecular spacing0.00.00.1-0.10.1-0.1-0.00.10.0-0.2-0.1
Bone: trabecular thickness0.40.50.60.70.80.70.70.70.70.80.7
Bone: trabecular tissue density4.56.67.1-2.7-2.3-2.7-2.6-2.4-2.6-2.6-2.7
Water consumed over 24 hours0.30.40.50.70.60.70.70.60.60.70.7
Number of responses in last shaping day0.10.20.40.60.40.50.30.10.40.40.4