Hub : Genes

Reck

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Reck 0.12 0.07 5.8e-13 0.09 0.08 0.09 0.08 2.6e-10 6.9e-09 6.8e-10 4.2e-09
2 IC gene expression Reck 0.31 0.15 1.8e-09 0.22 0.21 0.21 0.22 7.6e-10 2.6e-09 2.5e-09 1.7e-09
3 Adipose isoform ratio XM_063287725.1 0.03 0.02 3.2e-04 0.02 0.02 0.02 0.02 5.6e-03 1.4e-03 2.2e-03 1.8e-03
4 RMTg gene expression Reck 0.19 0.11 6.7e-05 0.13 0.14 0.14 0.14 2.7e-04 2.0e-04 1.2e-04 1.3e-04
5 PL gene expression Reck 0.3 0.09 0.0e+00 0.43 0.46 0.46 0.46 1.4e-50 1.9e-55 2.3e-55 1.3e-55
6 Adipose isoform ratio NM_001415923.1 0.02 0.02 1.6e-03 0.02 0.02 0.02 0.02 1.8e-03 1.4e-03 2.1e-03 2.2e-03
7 IL mRNA stability Reck 0.13 0.09 6.1e-03 0.07 0.01 0.2 0.07 1.1e-02 1.8e-01 1.9e-05 1.1e-02
8 NAcc mRNA stability Reck 0.02 0.01 1.8e-03 0.02 0.02 0.01 0.01 1.2e-03 3.5e-04 2.7e-03 1.8e-03
9 Adipose alternative TSS XM_063287725.1 0.13 0.07 0.0e+00 0.15 0.15 0.15 0.15 1.9e-16 2.6e-16 2.7e-16 3.4e-16
10 Brain mRNA stability Reck 0.07 0.05 1.9e-06 0.08 0.07 0.07 0.08 5.0e-08 3.2e-07 3.9e-07 7.1e-08
11 BLA gene expression Reck 0.37 0.16 2.2e-13 0.25 0.22 0.22 0.23 2.1e-13 3.9e-12 4.6e-12 2.2e-12
12 pVTA gene expression Reck 0.14 0.09 5.6e-06 0.07 0.04 0.05 0.06 1.9e-06 4.8e-04 1.0e-04 9.5e-06
13 Adipose alternative TSS NM_001415923.1 0.21 0.1 0.0e+00 0.25 0.25 0.25 0.26 7.1e-28 1.0e-27 5.5e-28 4.4e-28
14 Adipose alternative TSS XM_063287725.1 0.21 0.1 0.0e+00 0.26 0.25 0.26 0.26 3.8e-28 5.2e-28 3.1e-28 2.2e-28
15 Adipose alternative TSS NM_001415923.1 0.21 0.1 0.0e+00 0.25 0.25 0.25 0.25 1.6e-27 1.2e-27 6.0e-28 5.2e-28
16 Brain gene expression Reck 0.34 0.12 0.0e+00 0.4 0.43 0.43 0.42 1.6e-39 1.6e-43 1.7e-43 1.4e-42
17 NAcc gene expression Reck 0.26 0.09 0.0e+00 0.3 0.3 0.32 0.31 1.9e-46 1.1e-46 9.0e-49 1.5e-48
18 IL gene expression Reck 0.51 0.16 2.1e-13 0.47 0.52 0.52 0.52 1.0e-12 2.1e-14 8.6e-15 1.4e-14
19 PL mRNA stability Reck 0.05 0.04 2.0e-03 0.01 0.03 0.03 0.03 4.5e-02 2.9e-04 3.8e-04 4.8e-04
20 LHb gene expression Reck 0.32 0.19 1.0e-03 0.11 0.11 0.16 0.12 1.2e-03 1.3e-03 1.1e-04 7.7e-04
21 Liver gene expression Reck 0.17 0.09 2.1e-13 0.06 0.11 0.1 0.11 3.9e-07 2.4e-12 1.0e-10 9.4e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density1.73.04.21.5-1.91.7-1.7-1.8-1.8-2.0-1.81.7-1.7-1.8-1.8-1.81.8-1.8-1.9-1.8-1.8-0.2-1.7-1.4
Area under the delay curve0.40.51.6-0.70.6-0.70.50.60.81.30.8-0.60.60.70.60.6-0.60.61.00.80.7-0.2-0.10.9
BMI with tail2.17.49.82.4-2.62.8-3.0-3.0-2.9-2.5-2.92.8-2.8-2.7-2.7-2.92.9-2.9-3.0-3.1-3.0-1.1-2.6-1.3
BMI without tail2.16.57.82.7-2.72.8-2.7-2.8-2.8-2.6-2.82.7-2.5-2.5-2.6-2.62.6-2.6-2.7-2.7-2.7-1.4-2.1-1.3
Body weight3.214.017.94.0-3.64.2-4.2-4.1-4.0-3.0-3.94.1-3.8-3.9-3.9-3.93.9-3.8-3.7-3.7-3.8-3.3-3.4-0.6
Weight adjusted by age0.30.51.20.6-0.10.6-1.0-0.7-0.6-0.1-0.50.8-0.9-0.9-0.9-0.80.8-0.8-0.4-0.4-0.6-1.1-0.70.7
Bone surface1.01.82.31.3-1.21.4-1.4-1.4-1.4-1.3-1.41.5-1.4-1.5-1.5-1.41.4-1.4-1.4-1.5-1.4-0.8-1.3-0.5
Bone volume0.91.72.21.0-1.31.3-1.3-1.3-1.3-1.5-1.41.3-1.3-1.4-1.4-1.41.4-1.4-1.4-1.4-1.4-0.3-1.4-0.8
Breakpoint value in progressive ratio session1.11.410.7-0.01.6-0.50.00.70.82.10.90.0-0.30.00.10.2-0.30.41.31.10.9-2.2-0.13.3
Number of licking bursts3.25.17.12.3-2.52.4-2.3-2.4-2.5-2.7-2.52.0-2.4-2.4-2.4-2.32.3-2.3-2.5-2.3-2.4-0.8-1.8-1.6
Context. condit. distance diff. score0.00.00.2-0.30.3-0.20.10.20.1-0.00.1-0.0-0.00.10.0-0.00.0-0.0-0.00.10.00.4-0.1-0.1
Locomotion velocity, session 11.31.49.41.20.40.9-1.1-0.5-0.61.4-0.41.0-0.9-1.1-1.0-0.70.7-0.60.0-0.5-0.3-3.1-1.02.7
Locomotion distance, session 10.30.42.80.8-0.10.6-0.6-0.3-0.40.7-0.30.5-0.5-0.5-0.5-0.40.4-0.30.0-0.4-0.2-1.7-0.31.3
Locomotion velocity, session 22.42.84.91.7-2.11.7-1.6-1.8-1.8-2.0-1.81.7-1.4-1.5-1.3-1.71.7-1.7-1.8-2.2-1.7-0.4-1.2-1.5
Locomotion distance, session 20.70.93.41.8-1.51.3-0.9-1.1-1.0-0.5-0.90.7-0.8-0.8-0.8-0.70.7-0.6-0.6-0.9-0.5-1.70.10.1
Locomotion velocity, session 30.20.21.70.40.20.2-0.2-0.0-0.10.8-0.00.3-0.3-0.3-0.3-0.10.1-0.00.2-0.00.1-1.3-0.21.3
Locomotion distance, session 33.64.05.81.7-1.22.1-2.3-2.0-2.0-0.9-2.02.3-2.3-2.3-2.4-2.22.2-2.1-1.8-2.0-2.0-2.0-2.30.5
Stereotopy head waving bouts, day 30.60.72.40.00.7-0.40.50.60.61.50.7-0.70.40.50.40.7-0.70.71.01.20.9-1.10.91.6
Stereotopy head waving duration, day 30.60.71.6-0.30.8-0.70.70.80.81.10.8-1.00.70.60.60.9-0.91.01.01.31.0-0.40.91.0
Locomotion velocity, session 70.10.10.1-0.30.2-0.30.30.30.30.30.3-0.20.30.30.40.3-0.30.30.30.20.30.20.10.2
Locomotion distance, session 70.30.30.60.6-0.40.6-0.6-0.5-0.5-0.2-0.50.8-0.6-0.6-0.5-0.60.6-0.6-0.4-0.5-0.5-0.7-0.70.3
Stereotopy head waving bouts, day 71.82.03.21.4-0.81.6-1.7-1.5-1.5-0.5-1.51.4-1.7-1.7-1.8-1.51.5-1.5-1.4-1.1-1.4-1.6-1.40.4
Stereotopy head waving duration, day 70.40.51.01.0-0.50.9-0.8-0.8-0.8-0.3-0.70.6-0.8-0.9-0.9-0.60.6-0.5-0.6-0.4-0.6-1.0-0.30.2
Locomotion velocity, session 80.50.61.90.30.3-0.40.80.60.60.90.7-0.50.70.70.70.9-0.90.91.00.81.1-0.81.40.9
Locomotion distance, session 80.10.11.20.7-0.10.3-0.1-0.1-0.10.4-0.00.3-0.1-0.2-0.1-0.00.0-0.00.20.00.2-1.10.40.8
Degree of sensitization distance2.42.54.0-1.00.9-1.61.81.61.60.91.6-1.71.91.82.01.7-1.71.71.61.71.71.11.8-0.0
Degree of sensitization stereotypy2.42.63.71.2-1.01.7-1.9-1.7-1.7-1.0-1.71.7-1.8-1.9-1.9-1.71.7-1.7-1.7-1.6-1.8-1.1-1.8-0.1
Conditioned locomotion0.40.41.90.10.40.4-0.6-0.3-0.30.8-0.30.7-0.7-0.7-0.7-0.50.5-0.4-0.1-0.4-0.3-1.2-1.11.4
Cocaine response after cond. corrected1.51.84.9-1.32.0-1.21.11.41.32.21.4-0.90.90.90.91.2-1.21.21.51.31.4-0.50.82.1
Cocaine response after cond. not corrected2.02.45.4-1.11.9-1.31.41.61.52.31.6-1.11.21.21.21.5-1.51.51.81.71.7-0.71.42.1
Cocaine response before conditioning0.20.20.80.9-0.90.5-0.2-0.5-0.5-0.8-0.40.2-0.2-0.2-0.2-0.20.2-0.2-0.3-0.0-0.3-0.20.4-0.7
Saline control response0.40.52.21.0-0.40.9-0.8-0.7-0.7-0.0-0.60.9-0.7-0.7-0.7-0.50.5-0.5-0.4-0.3-0.5-1.5-0.40.7
Bone: connectivity density1.11.72.71.1-1.61.2-1.3-1.4-1.3-1.6-1.41.2-1.2-1.4-1.4-1.21.3-1.3-1.5-1.5-1.40.1-1.4-1.2
Bone: cortical apparent density0.20.32.0-0.2-0.5-0.20.30.00.1-0.9-0.0-0.20.30.40.40.1-0.10.1-0.2-0.2-0.01.30.4-1.4
Bone: cortical area2.13.27.01.6-2.31.7-1.5-1.9-1.9-2.6-1.91.5-1.5-1.4-1.4-1.71.7-1.7-2.1-2.1-1.80.2-1.1-2.2
Bone: cortical porosity0.10.20.2-0.20.3-0.40.50.40.40.30.4-0.50.30.40.30.5-0.50.50.40.50.50.30.30.0
Bone: cortical porosity0.10.10.20.20.00.2-0.2-0.1-0.2-0.0-0.20.2-0.4-0.3-0.4-0.20.2-0.2-0.2-0.1-0.2-0.3-0.40.2
Bone: cortical thickness1.11.84.50.5-1.51.0-1.0-1.3-1.3-2.1-1.41.0-1.1-1.0-1.0-1.31.3-1.3-1.6-1.6-1.41.0-1.0-2.1
Bone: cortical thickness0.30.41.5-0.70.5-0.70.70.60.6-0.20.5-0.50.70.70.70.5-0.50.50.40.00.51.20.7-0.7
Bone: cortical tissue density0.20.21.6-0.2-0.4-0.30.40.10.1-0.70.1-0.30.40.40.40.2-0.20.2-0.1-0.10.11.30.4-1.2
Condit. Reinf. active minus inactive responses0.30.30.70.9-0.70.6-0.3-0.5-0.6-0.7-0.60.4-0.5-0.4-0.4-0.40.4-0.4-0.6-0.7-0.4-0.20.2-0.7
Condit. Reinf. active-inactive response ratio0.60.70.9-0.90.9-0.91.00.90.90.50.8-0.90.80.80.80.9-0.90.90.80.70.80.80.80.1
Condit. Reinf. active responses1.92.44.42.1-2.01.7-1.3-1.7-1.7-1.9-1.71.4-1.5-1.4-1.4-1.41.4-1.4-1.6-1.7-1.4-0.7-0.5-1.4
Condit. Reinf. inactive responses2.12.65.62.2-2.41.8-1.4-1.8-1.8-2.3-1.81.2-1.2-1.4-1.4-1.41.4-1.4-1.7-1.6-1.5-0.4-0.5-1.9
Incentive salience index mean3.44.27.22.7-2.32.4-2.0-2.3-2.3-2.0-2.22.0-2.1-2.0-2.1-2.02.0-2.0-2.1-2.1-1.9-1.5-1.2-1.1
Condit. Reinf. lever presses8.511.919.54.4-3.84.0-3.6-3.8-3.8-2.9-3.73.4-3.6-3.5-3.5-3.53.5-3.5-3.4-3.3-3.3-3.0-2.6-1.0
Condit. Reinf. active minus inactive responses0.70.91.30.7-1.10.9-0.9-1.0-1.0-1.1-1.01.1-0.8-0.8-0.8-1.01.0-1.0-1.1-1.1-1.10.0-0.7-0.9
Condit. Reinf. active-inactive response ratio0.30.40.70.1-0.60.4-0.5-0.5-0.6-0.8-0.60.6-0.5-0.4-0.4-0.60.7-0.7-0.8-0.8-0.80.5-0.6-0.8
Condit. Reinf. active responses1.82.53.91.7-2.01.7-1.5-1.7-1.7-1.7-1.71.8-1.4-1.4-1.4-1.61.6-1.7-1.7-1.6-1.7-0.7-1.1-1.1
Condit. Reinf. inactive responses1.82.44.91.9-2.21.7-1.4-1.7-1.7-1.9-1.71.5-1.3-1.3-1.3-1.51.5-1.5-1.6-1.5-1.5-0.6-0.9-1.4
Condit. Reinf. lever presses2.02.76.51.7-2.51.6-1.4-1.8-1.7-2.4-1.81.5-1.2-1.2-1.2-1.41.4-1.5-1.9-1.7-1.70.2-0.7-2.3
Condit. Reinf. lever reinforcers received1.92.74.71.9-2.21.8-1.6-1.8-1.8-1.8-1.81.8-1.5-1.5-1.5-1.61.6-1.6-1.7-1.7-1.7-0.7-1.0-1.3
Conditioned reinforcement - actives0.30.40.90.1-0.20.5-0.8-0.6-0.50.1-0.60.7-0.9-0.8-0.7-0.80.8-0.8-0.5-0.7-0.7-0.7-0.90.5
Conditioned reinforcement - inactives0.10.20.8-0.10.7-0.4-0.00.30.40.80.40.2-0.00.10.3-0.00.0-0.00.40.20.1-0.2-0.50.9
Conditioned locomotion0.91.25.00.00.10.8-1.4-0.8-0.80.2-0.91.4-1.2-1.1-1.0-1.31.3-1.3-0.8-1.2-1.2-1.0-2.20.9
Patch foraging indifference point 0 sec1.73.19.11.3-0.11.4-2.2-1.3-1.30.7-1.21.9-2.0-1.9-1.9-1.81.8-1.7-0.9-0.8-1.5-2.8-3.02.3
Patch foraging indifference point AUC6.99.913.13.6-3.23.6-3.3-3.4-3.5-2.9-3.43.5-3.1-3.2-3.2-3.33.3-3.2-3.1-3.2-3.2-2.5-2.5-1.1
Delay disc. indifference point, 0s delay1.11.22.1-0.71.5-1.11.01.11.21.41.2-1.01.01.21.30.9-1.01.01.41.21.2-0.10.71.2
Delay disc. indifference point, 16s delay0.80.93.7-0.81.2-0.80.40.90.91.71.0-0.50.60.40.20.6-0.60.71.20.90.8-0.8-0.61.9
Delay disc. indifference point, 2s delay0.10.10.40.2-0.20.2-0.3-0.3-0.2-0.4-0.20.0-0.2-0.1-0.1-0.20.3-0.3-0.3-0.3-0.40.4-0.6-0.6
Delay disc. indifference point, 24s delay0.20.20.5-0.10.1-0.50.60.50.50.20.6-0.70.60.60.50.6-0.60.60.60.50.60.30.4-0.0
Delay disc. indifference point, 4s delay0.10.10.9-0.90.1-0.30.20.20.30.60.4-0.30.30.30.20.2-0.20.20.40.20.3-0.10.00.3
Delay disc. indifference point, 8s delay0.00.00.30.2-0.5-0.0-0.0-0.10.10.00.1-0.10.20.30.20.0-0.00.00.20.1-0.0-0.1-0.1-0.2
Indifference point function ln k1.83.14.6-1.92.1-2.01.71.92.02.01.9-2.01.61.71.71.7-1.71.71.91.91.81.01.11.2
Indifference point function log k1.83.14.6-1.92.1-2.01.71.92.02.01.9-2.01.61.71.71.7-1.71.71.91.91.81.01.11.2
Patch foraging total patch changes 0 sec2.14.010.61.7-0.51.8-2.6-1.7-1.70.3-1.62.2-2.4-2.3-2.3-2.12.1-2.0-1.4-1.2-1.9-2.8-3.32.0
Patch foraging total patch changes 12 sec3.95.07.51.9-1.82.3-2.6-2.4-2.3-1.8-2.32.6-2.4-2.4-2.4-2.42.4-2.4-2.3-2.1-2.4-1.4-2.7-0.4
Patch foraging total patch changes 18 sec0.61.01.41.2-1.01.1-1.2-1.0-1.0-0.8-1.01.2-0.9-0.9-0.9-1.01.0-1.0-0.9-0.8-1.0-1.0-1.1-0.1
Patch foraging total patch changes 24 sec2.84.76.52.0-1.72.4-2.4-2.2-2.3-1.2-2.32.6-2.5-2.3-2.4-2.42.4-2.4-2.1-2.1-2.3-2.0-2.10.1
Patch foraging total patch changes 6 sec4.46.810.82.5-1.82.7-3.1-2.7-2.6-1.0-2.63.0-2.9-2.9-2.9-2.82.8-2.7-2.3-2.3-2.6-2.9-3.30.8
Patch foraging time to switch 0 sec2.55.26.9-2.41.6-2.52.62.42.41.22.3-2.62.52.62.52.5-2.52.42.12.22.32.32.0-0.2
Patch foraging water rate 0 sec3.06.39.61.8-1.22.5-3.0-2.4-2.5-0.8-2.53.0-2.9-2.9-3.0-2.92.8-2.8-2.3-2.5-2.7-2.4-3.10.8
Patch foraging water rate 12 sec0.10.10.6-0.20.20.3-0.3-0.2-0.20.7-0.20.4-0.5-0.4-0.4-0.30.3-0.3-0.1-0.3-0.2-0.70.10.8
Patch foraging water rate 18 sec1.01.62.60.4-0.61.1-1.2-1.2-1.2-1.0-1.31.4-1.6-1.5-1.4-1.51.5-1.5-1.5-1.6-1.50.0-1.2-0.6
Patch foraging water rate 24 sec0.20.31.0-0.2-0.30.1-0.2-0.2-0.3-0.8-0.40.3-0.4-0.3-0.3-0.40.5-0.5-0.6-0.8-0.61.0-0.6-1.0
Patch foraging water rate 6 sec0.40.61.40.6-0.40.9-0.7-0.7-0.9-0.5-0.90.8-1.2-1.0-0.9-0.70.7-0.7-0.8-0.8-0.7-0.60.1-0.0
Seeking ratio, delayed vs. immediate footshock4.75.77.71.5-2.62.4-2.8-2.7-2.5-2.1-2.52.5-2.4-2.3-2.3-2.72.7-2.7-2.5-2.5-2.7-1.2-2.5-1.1
Distance traveled before self-admin1.82.44.21.4-1.51.9-1.5-1.6-1.8-0.9-1.61.7-1.9-1.8-1.9-1.61.6-1.5-1.4-1.3-1.3-2.0-0.60.2
Distance traveled after self-admin0.40.52.10.7-1.40.60.1-0.5-0.7-1.1-0.60.4-0.5-0.4-0.5-0.30.3-0.3-0.7-0.7-0.30.30.6-1.4
Extensor digitorum longus weight4.819.124.54.9-4.54.8-4.7-4.7-4.7-3.9-4.64.7-4.6-4.5-4.4-4.64.6-4.5-4.4-4.4-4.4-3.1-4.0-1.5
Bone: elastic displacement3.23.78.1-2.82.4-2.31.92.22.11.42.0-1.91.92.01.91.8-1.81.81.71.71.62.30.90.3
Bone: elastic work1.21.69.2-2.10.8-1.51.21.21.2-0.41.0-1.11.21.31.20.9-0.90.80.50.50.63.00.3-1.6
Bone: endosteal estimation0.61.33.21.8-1.21.5-1.2-1.3-1.3-1.0-1.21.1-0.9-1.0-1.0-1.11.1-1.0-1.0-1.0-1.0-1.5-0.5-0.1
Bone: endosteal perimeter0.81.73.21.8-1.21.6-1.4-1.4-1.4-0.7-1.31.4-1.3-1.3-1.3-1.31.3-1.3-1.1-1.2-1.2-1.8-0.90.2
Epididymis fat weight0.20.71.81.2-1.30.9-0.7-0.9-0.9-1.3-0.80.8-0.4-0.6-0.6-0.70.7-0.6-0.8-0.9-0.7-0.2-0.2-1.0
Delta time in closed arm before/after self-admin0.50.42.3-0.1-1.20.4-0.1-0.5-0.5-1.4-0.60.1-0.2-0.1-0.0-0.30.3-0.4-0.7-0.6-0.50.80.2-1.5
Delta time in open arm before/after self-admin0.30.31.20.00.4-0.40.30.40.51.10.60.00.40.30.30.4-0.40.50.70.60.6-0.6-0.11.0
Diff in mean of infusions in LGA sessions0.50.61.1-0.1-0.1-0.61.00.80.6-0.50.6-1.00.80.90.80.8-0.80.80.50.50.71.00.9-0.8
Delay discount exponential model param0.30.41.40.6-0.50.6-0.4-0.5-0.7-1.2-0.70.5-0.5-0.6-0.4-0.40.4-0.5-0.8-0.6-0.60.30.2-0.9
Extinction: sum of active levers before priming3.33.65.2-1.31.6-2.11.92.02.22.32.2-2.01.62.12.02.0-2.02.02.32.12.20.41.11.5
Active lever presses in extinction session 60.10.10.4-0.50.2-0.30.10.30.30.50.3-0.10.10.1-0.10.1-0.10.10.30.10.2-0.1-0.20.6
Bone: final force0.61.03.31.5-1.81.1-0.6-1.1-1.1-1.6-1.10.7-0.7-0.7-0.7-0.70.7-0.7-1.0-0.8-0.7-0.30.2-1.3
Bone: final moment0.50.83.01.2-1.70.9-0.4-0.9-0.9-1.6-0.90.5-0.5-0.5-0.5-0.50.5-0.5-0.9-0.6-0.5-0.00.4-1.5
Food consumed during 24 hour testing period0.20.30.91.0-0.90.8-0.6-0.6-0.6-0.4-0.60.6-0.4-0.4-0.4-0.50.5-0.5-0.4-0.4-0.4-0.9-0.1-0.0
Glucose2.74.35.42.3-1.92.3-2.2-2.3-2.3-1.7-2.22.3-2.1-2.2-2.1-2.22.2-2.2-2.1-2.2-2.1-1.6-1.8-0.6
Heart weight0.30.51.61.0-1.30.9-0.6-1.0-0.8-0.7-0.80.4-0.7-0.7-0.6-0.50.5-0.5-0.7-0.6-0.5-0.60.1-0.6
Delay discount hyperbolic model param0.20.21.00.5-0.40.4-0.2-0.4-0.5-1.0-0.60.4-0.3-0.4-0.3-0.30.3-0.3-0.7-0.5-0.40.40.3-0.8
Intermittent access intake day 1-15 change0.51.01.70.6-0.91.0-0.9-1.0-1.1-1.3-1.10.9-1.1-0.9-0.8-1.11.1-1.2-1.2-1.2-1.10.1-0.6-1.0
Intermittent access intake escalation0.30.71.60.4-0.80.8-0.6-0.8-0.9-1.3-0.90.6-0.8-0.6-0.6-0.90.9-0.9-1.1-1.0-0.90.3-0.2-1.1
Intermittent access intake escalation 21.21.33.60.4-1.21.0-0.8-1.1-1.2-1.9-1.30.9-0.9-0.7-0.7-1.11.1-1.2-1.5-1.5-1.30.8-0.5-1.9
Intermitt. access day 1 inactive lever presses0.41.43.92.0-1.01.2-1.3-1.2-1.2-1.0-1.11.4-1.0-1.1-1.1-1.11.1-1.1-1.0-1.1-1.1-1.0-1.4-0.2
Intermitt. access day 15 inactive lever presses0.00.10.5-0.1-0.10.2-0.3-0.3-0.10.2-0.10.5-0.2-0.1-0.2-0.30.3-0.20.0-0.0-0.2-0.7-0.00.5
Intermitt. access escalation Index0.20.31.51.2-0.20.6-0.6-0.5-0.5-0.6-0.50.2-0.5-0.4-0.5-0.50.5-0.5-0.4-0.1-0.4-0.6-0.60.0
Intermittent access day 1 total infusions0.50.75.3-0.91.4-0.6-0.20.50.61.70.60.10.0-0.2-0.20.1-0.10.20.70.40.3-0.9-1.22.3
Intermittent access day 15 total infusions0.50.72.20.0-0.30.6-1.0-0.7-0.7-0.5-0.80.9-0.9-0.9-0.9-1.01.0-1.0-0.8-1.0-1.0-0.3-1.50.1
Intermittent access terminal intake (last 3 days)0.81.03.30.4-0.20.8-1.2-0.8-0.8-0.7-0.91.1-1.2-1.2-1.1-1.21.2-1.2-1.0-1.1-1.2-0.5-1.80.3
Intermittent access total infusions1.11.34.20.4-0.10.8-1.4-0.9-0.9-0.2-0.91.4-1.2-1.4-1.3-1.31.3-1.2-0.9-1.1-1.2-1.0-2.10.9
Intermittent access day 1 locomotion0.40.53.2-0.71.2-0.5-0.20.40.51.40.40.30.2-0.1-0.10.1-0.10.10.50.10.1-0.6-1.61.8
Intermittent access day 15 total locomotion0.20.42.5-1.11.1-0.4-0.30.30.41.00.30.40.0-0.4-0.3-0.20.2-0.10.3-0.0-0.1-0.4-1.11.6
Intermittent access total locomotion0.30.31.7-1.31.0-0.60.00.50.50.80.40.10.30.10.20.1-0.10.10.3-0.1-0.00.4-1.10.8
Intermittent access standard deviation0.51.01.70.3-0.50.9-1.2-1.0-0.9-0.4-1.01.1-1.3-1.2-1.1-1.21.2-1.2-0.9-1.0-1.1-0.7-1.30.1
Left kidney weight0.21.23.91.7-1.41.4-1.1-1.2-1.1-0.5-1.01.1-1.1-0.9-0.9-1.01.0-0.9-0.7-0.7-0.7-2.0-0.40.5
Right kidney weight0.10.72.91.6-1.71.0-0.5-0.9-0.9-1.1-0.80.5-0.4-0.3-0.4-0.40.4-0.4-0.7-0.7-0.5-0.6-0.1-0.8
Cocaine induced anxiety0.30.40.7-0.50.7-0.60.60.70.70.40.7-0.50.70.90.90.7-0.70.70.60.50.60.40.70.1
Post-drug Anxiety0.10.10.80.9-0.30.3-0.1-0.1-0.2-0.0-0.10.10.00.20.20.1-0.10.10.10.10.1-0.80.50.2
Baseline Anxiety0.30.31.71.1-1.30.6-0.3-0.7-0.6-0.7-0.50.1-0.2-0.2-0.2-0.20.2-0.2-0.4-0.2-0.3-0.30.1-0.8
Tail length0.93.67.52.7-2.72.3-1.7-2.1-2.2-2.2-2.12.0-1.7-1.7-1.7-1.71.7-1.6-1.8-1.7-1.7-1.7-0.6-1.1
Length with tail1.14.68.62.9-2.22.6-2.3-2.3-2.3-1.3-2.22.5-2.2-2.3-2.2-2.02.0-1.9-1.8-1.8-1.9-2.9-1.60.4
Length without tail0.20.53.20.40.10.6-0.8-0.5-0.40.8-0.30.8-0.6-0.6-0.6-0.50.5-0.5-0.0-0.2-0.3-1.8-0.71.6
Times rat made contact with spout0.60.71.40.5-0.90.7-0.9-0.8-0.8-1.2-0.90.8-0.7-0.7-0.7-0.90.9-0.9-1.0-0.8-1.00.2-1.1-0.8
Lifetime Intake1.01.23.80.20.20.7-1.3-0.8-0.70.2-0.81.3-1.3-1.4-1.3-1.21.2-1.1-0.7-0.9-1.0-1.4-1.91.4
Liver weight, left0.20.40.80.20.1-0.40.60.50.50.30.6-0.90.70.60.60.7-0.70.70.70.80.7-0.10.70.2
Liver weight, right0.61.12.1-1.51.0-1.21.11.11.10.91.1-0.91.21.11.11.1-1.11.11.00.81.00.90.90.2
Locomotor activity0.00.00.30.5-0.2-0.10.20.10.10.00.2-0.20.20.10.10.1-0.10.20.20.10.2-0.00.2-0.0
Locomotor testing distance0.30.51.40.10.7-0.50.60.70.71.10.8-0.50.50.50.50.6-0.60.60.90.80.8-0.60.51.2
Locomotor testing rearing0.10.31.71.3-0.70.6-0.4-0.4-0.5-0.4-0.40.5-0.3-0.4-0.4-0.40.4-0.4-0.2-0.3-0.2-0.9-0.00.0
Locomotion in novel chamber0.20.21.7-0.8-0.1-0.50.50.40.3-0.20.2-0.50.50.60.50.3-0.20.2-0.00.00.11.3-0.3-0.9
Locomotion in novel chamber post-restriction0.81.35.70.4-1.81.0-0.5-1.0-1.2-2.4-1.20.6-0.8-0.6-0.6-0.80.8-0.9-1.4-1.3-0.90.80.1-2.2
Fecal boli incidents, locomotor time 10.40.61.3-0.70.4-1.00.80.80.90.40.9-0.81.11.11.00.8-0.80.80.80.70.61.0-0.0-0.3
Change in fecal boli incidents, locomotor task0.90.81.50.9-0.11.0-1.2-0.8-0.9-0.3-0.91.1-0.9-1.0-0.9-1.11.1-1.0-0.8-0.9-1.0-1.2-0.70.7
Time >=10cm from walls, locomotor time 10.30.41.40.40.60.3-0.6-0.2-0.20.6-0.20.5-0.7-0.7-0.6-0.60.6-0.5-0.1-0.0-0.2-1.1-0.81.2
Bouts of movement, locomotor time 11.92.13.2-1.31.3-1.61.81.71.61.41.5-1.61.71.81.41.4-1.41.41.51.51.51.01.20.3
Total resting periods, locomotor time 12.52.74.3-1.71.3-1.82.11.91.81.21.7-1.91.92.01.61.6-1.61.61.61.61.61.61.6-0.0
Rest time, locomotor task time 12.22.77.7-1.50.5-1.62.21.51.4-0.21.3-2.01.91.91.61.6-1.61.51.01.11.32.82.3-1.8
Distance moved, locomotor task time 11.92.96.31.6-0.81.8-2.1-1.6-1.6-0.3-1.51.9-2.0-2.2-1.9-1.71.7-1.6-1.3-1.3-1.4-2.5-2.01.4
Vertical activity count, locomotor time 10.51.36.31.2-0.11.1-1.3-0.8-0.90.3-0.71.0-1.4-1.5-1.5-0.90.9-0.8-0.4-0.2-0.4-2.5-0.91.9
Time >=10cm from walls, locomotor time 20.10.10.40.0-0.10.2-0.0-0.2-0.20.2-0.10.2-0.3-0.3-0.5-0.00.0-0.0-0.00.00.2-0.60.70.3
Bouts of movement, locomotor time 20.30.40.80.9-0.90.8-0.7-0.7-0.7-0.1-0.70.8-0.7-0.2-0.5-0.70.7-0.7-0.7-0.5-0.6-0.5-0.7-0.3
Total resting periods, locomotor time 20.10.20.40.7-0.60.5-0.5-0.5-0.50.1-0.50.6-0.50.0-0.3-0.50.5-0.5-0.4-0.3-0.4-0.3-0.6-0.2
Rest time, locomotor task time 20.70.81.3-1.11.1-1.01.11.11.00.60.9-1.00.80.90.70.9-0.90.80.80.80.81.11.1-0.0
Distance moved, locomotor task time 20.20.21.20.2-1.10.4-0.1-0.5-0.4-1.1-0.40.0-0.0-0.3-0.30.1-0.10.0-0.4-0.3-0.10.20.5-1.1
Vertical activity count, locomotor time 20.10.10.60.3-0.70.5-0.2-0.4-0.4-0.5-0.3-0.0-0.2-0.4-0.50.0-0.00.0-0.10.20.1-0.70.8-0.1
Light reinforcement 10.41.19.41.70.00.8-0.6-0.4-0.41.3-0.20.6-0.8-0.6-0.6-0.20.2-0.10.40.20.2-3.10.12.4
Light reinforcement 20.71.18.11.30.80.5-0.30.1-0.11.50.10.2-0.6-0.7-0.70.1-0.10.20.60.80.6-2.80.12.8
Bone: marrow area0.71.43.41.8-1.41.5-1.3-1.3-1.4-1.2-1.31.1-1.0-1.1-1.0-1.11.1-1.1-1.1-1.1-1.1-1.3-0.5-0.4
Bone: maximum diameter1.83.56.32.1-2.42.0-1.7-2.0-2.1-2.5-2.01.6-1.7-1.7-1.7-1.71.7-1.8-2.0-2.0-1.8-0.6-1.1-1.8
Bone: maximum force1.73.17.42.3-2.72.0-1.4-1.9-2.0-2.5-1.91.5-1.5-1.5-1.5-1.51.5-1.5-1.8-1.8-1.5-0.6-0.4-1.9
Bone: maximum moment1.42.46.42.0-2.51.7-1.1-1.7-1.7-2.4-1.71.2-1.2-1.2-1.3-1.21.2-1.3-1.7-1.6-1.3-0.3-0.2-1.9
Mean time between licks in bursts1.22.96.8-0.70.9-1.52.01.61.60.81.7-2.11.91.91.92.1-2.12.11.71.82.01.02.6-0.2
Mean num. licks in bursts1.52.43.2-1.61.5-1.71.51.71.71.51.7-1.31.81.81.81.5-1.51.61.61.51.51.01.10.7
Cd content in liver0.30.31.01.0-0.50.7-0.5-0.5-0.6-0.7-0.60.4-0.5-0.5-0.5-0.50.5-0.5-0.5-0.3-0.4-0.70.2-0.1
Co content in liver0.81.01.8-0.71.2-0.90.81.01.01.31.1-0.90.80.90.90.9-0.91.01.21.11.1-0.30.91.3
Cu content in liver2.93.45.0-1.71.5-1.92.11.91.91.31.9-2.12.02.02.02.0-2.02.01.91.81.91.32.20.2
Fe content in liver2.02.53.6-1.11.5-1.41.61.61.61.91.7-1.11.51.61.61.7-1.71.71.91.71.9-0.21.91.4
K content in liver0.30.30.9-0.40.8-0.40.40.50.50.90.5-0.60.30.30.30.5-0.50.50.60.70.6-0.40.51.0
Mg content in liver0.20.20.7-0.80.8-0.50.40.50.50.70.5-0.60.30.30.30.3-0.30.30.40.70.30.2-0.10.6
Mn content in liver0.91.02.80.8-1.51.0-0.7-1.1-1.1-1.7-1.10.6-0.8-0.8-0.8-0.90.9-0.9-1.2-1.0-1.00.3-0.5-1.5
Na content in liver4.34.78.9-1.61.5-2.12.52.22.21.32.2-2.22.52.52.52.4-2.42.42.22.12.41.33.00.2
Rb content in liver5.96.99.9-3.12.9-2.82.72.92.82.52.8-2.82.62.62.62.6-2.62.62.72.92.71.52.31.4
Se content in liver1.51.84.62.0-2.11.4-1.0-1.5-1.4-1.8-1.41.2-1.0-1.0-1.0-1.11.1-1.1-1.4-1.4-1.2-0.3-0.3-1.6
Sr content in liver0.40.41.61.3-1.00.7-0.6-0.7-0.6-0.4-0.60.5-0.5-0.5-0.5-0.60.6-0.5-0.4-0.4-0.5-0.7-0.3-0.3
Zn content in liver0.10.10.50.1-0.3-0.10.40.10.1-0.40.1-0.40.30.30.30.4-0.40.40.10.10.20.50.7-0.7
Bone: minimum diameter0.00.10.4-0.2-0.1-0.10.10.00.0-0.40.0-0.10.30.20.30.1-0.10.1-0.1-0.2-0.10.60.1-0.7
Time in familiar zone, hab. session 10.60.64.6-0.8-0.2-0.30.0-0.1-0.0-1.2-0.2-0.10.10.10.1-0.30.3-0.4-0.6-0.7-0.62.1-0.5-1.8
Time in novel zone, hab. session 14.44.47.8-0.91.8-1.72.02.02.02.82.2-1.81.91.91.82.3-2.32.42.62.62.5-1.02.42.4
Total zone transitions, hab. session 10.00.00.30.1-0.2-0.10.20.10.1-0.10.1-0.30.10.30.20.3-0.30.30.2-0.00.30.10.5-0.2
Total locomotion distance, hab. session 10.30.53.00.6-1.10.4-0.1-0.5-0.5-1.4-0.5-0.0-0.2-0.1-0.2-0.20.2-0.3-0.6-0.6-0.40.90.3-1.7
Locomotion velocity, hab. session 11.11.54.11.5-1.91.2-0.9-1.3-1.3-2.0-1.30.6-1.0-0.9-1.0-1.01.0-1.0-1.4-1.3-1.10.2-0.3-1.9
Time in familiar zone, hab. session 20.70.73.3-1.10.1-0.90.90.70.7-0.20.6-1.10.90.90.80.7-0.70.60.40.50.51.80.8-1.1
Time in novel zone, hab. session 21.41.44.6-0.91.8-1.00.81.21.12.01.2-0.70.80.80.91.0-1.11.11.41.21.2-0.90.52.1
Total zone transitions, hab. session 20.30.31.31.0-0.60.7-0.6-0.6-0.6-0.1-0.50.4-0.6-0.6-0.6-0.50.5-0.4-0.4-0.5-0.3-1.2-0.10.4
Total locomotion distance, hab. session 20.50.71.41.2-1.11.0-0.8-0.9-0.9-0.9-0.90.6-0.8-0.7-0.8-0.80.8-0.8-0.9-1.0-0.8-0.5-0.2-0.6
Locomotion velocity, hab. session 20.81.11.81.4-1.41.2-1.0-1.1-1.2-1.2-1.20.7-1.0-0.9-1.0-1.01.0-1.0-1.1-1.2-1.0-0.5-0.4-0.8
Novel to familiar place preference ratio3.13.46.9-1.92.3-1.81.72.01.92.62.0-1.51.61.51.61.8-1.81.82.12.11.9-0.11.22.2
Novelty place preference4.04.37.9-2.22.6-2.12.02.22.22.82.2-1.81.81.81.92.0-2.02.12.32.32.10.21.42.2
Time in novel zone, NPP test5.35.79.8-2.52.9-2.42.32.62.53.12.6-2.12.22.12.22.4-2.42.42.72.72.50.31.72.4
Total zone transitions, NPP test0.30.42.01.2-0.70.8-0.5-0.6-0.60.1-0.50.5-0.5-0.5-0.5-0.40.4-0.3-0.2-0.5-0.2-1.40.10.5
Total locomotion distance, NPP test1.82.44.02.0-1.31.8-1.7-1.6-1.7-0.8-1.61.6-1.7-1.6-1.7-1.61.6-1.6-1.4-1.5-1.5-1.9-1.10.2
Locomotion velocity, NPP test2.63.65.02.2-1.72.1-2.1-2.0-2.0-1.2-2.02.0-2.1-2.0-2.0-2.02.0-2.0-1.8-2.0-1.9-1.8-1.6-0.1
Intraocular pressure3.34.87.02.1-1.52.3-2.5-2.2-2.3-1.6-2.22.3-2.4-2.5-2.6-2.32.3-2.2-2.1-2.1-2.2-2.0-2.60.1
Delta distance traveled before/after self-admin0.50.51.20.20.2-0.70.90.70.60.00.6-0.80.70.70.60.8-0.80.80.50.50.81.11.1-0.7
Delta ambulatory time before/after self-admin1.41.73.1-0.30.7-1.31.61.31.30.41.2-1.61.41.41.31.5-1.51.51.11.21.51.51.8-0.6
Parametrial fat weight0.40.92.0-0.60.7-0.70.80.80.81.30.9-0.70.91.00.90.9-0.91.01.11.11.0-0.51.41.0
Pavlov. Cond. lever latency5.67.011.1-3.33.0-3.02.72.93.02.42.9-2.52.82.72.72.7-2.72.72.72.72.62.11.91.0
Pavlov. Cond. magazine entry latency0.20.31.21.0-1.10.6-0.2-0.6-0.5-0.8-0.50.2-0.2-0.2-0.1-0.30.3-0.3-0.4-0.5-0.4-0.20.2-0.7
Pavlov. Cond. change in total contacts2.32.43.71.9-1.71.8-1.6-1.7-1.7-1.3-1.71.5-1.6-1.6-1.5-1.61.6-1.6-1.6-1.6-1.5-1.3-1.1-0.5
Pavlov. Cond. index score2.12.65.32.3-2.31.9-1.4-1.8-1.8-1.8-1.81.3-1.5-1.4-1.4-1.51.5-1.5-1.7-1.6-1.5-1.0-0.7-1.2
Pavlov. Cond. latency score2.12.64.82.2-2.21.9-1.5-1.8-1.8-1.8-1.81.4-1.6-1.5-1.5-1.61.6-1.6-1.7-1.6-1.5-1.0-0.8-1.1
Pavlov. Cond. lever contacts5.56.69.53.1-2.92.9-2.6-2.8-2.9-2.4-2.82.3-2.7-2.6-2.6-2.62.6-2.6-2.7-2.6-2.5-1.8-1.9-1.1
Pavlov. Cond. magazine entry number0.50.61.5-1.01.2-0.80.60.80.81.10.8-0.50.60.50.50.7-0.70.70.80.90.70.10.20.9
Pavlov. Cond. intertrial magazine entries0.10.10.40.6-0.50.4-0.3-0.4-0.4-0.6-0.40.4-0.4-0.3-0.4-0.20.2-0.3-0.4-0.4-0.2-0.20.0-0.4
Pavlov. Cond. lever-magazine prob. diff.2.12.65.62.2-2.41.8-1.4-1.8-1.8-2.0-1.81.3-1.5-1.3-1.4-1.51.5-1.5-1.7-1.7-1.5-0.7-0.7-1.5
Pavlov. Cond. response bias2.73.36.32.5-2.42.1-1.7-2.0-2.1-1.9-2.01.6-1.8-1.7-1.7-1.71.7-1.7-1.9-1.9-1.7-1.3-1.0-1.1
Pavlov. Cond. lever latency1.72.35.5-1.72.3-1.61.21.71.62.21.6-1.31.11.11.11.3-1.31.31.71.61.5-0.00.52.1
Pavlov. Cond. magazine entry latency1.11.32.6-0.80.2-1.11.31.01.00.31.0-1.31.41.41.41.3-1.31.31.01.01.11.11.6-0.6
Pavlov. Cond. change in total contacts0.50.86.10.5-1.70.40.1-0.6-0.5-1.8-0.6-0.10.00.10.1-0.10.1-0.2-0.7-0.6-0.41.30.8-2.5
Pavlov. Cond. index score0.30.43.10.1-1.1-0.00.4-0.1-0.1-1.1-0.1-0.30.50.50.50.3-0.30.2-0.2-0.10.01.10.9-1.8
Pavlov. Cond. latency score0.30.53.50.2-1.20.20.1-0.4-0.3-1.3-0.3-0.10.20.30.30.0-0.0-0.0-0.5-0.5-0.31.10.5-1.9
Pavlov. Cond. lever contacts1.11.54.31.4-2.11.2-0.9-1.4-1.3-2.0-1.31.0-0.7-0.7-0.7-0.90.9-1.0-1.3-1.2-1.10.2-0.1-2.0
Pavlov. Cond. magazine entry number0.40.53.30.20.80.3-0.6-0.1-0.21.0-0.10.5-0.7-0.7-0.7-0.40.4-0.40.10.0-0.2-1.5-0.91.8
Pavlov. Cond. intertrial magazine entries0.71.12.00.7-0.41.0-1.2-1.0-1.0-0.6-1.11.2-1.3-1.3-1.3-1.21.2-1.2-1.1-0.9-1.1-0.7-1.40.1
Pavlov. Cond. lever-magazine prob. diff.0.40.53.60.1-1.1-0.10.4-0.1-0.0-1.2-0.1-0.40.50.50.50.3-0.30.3-0.2-0.20.01.31.0-1.9
Pavlov. Cond. response bias0.40.63.60.7-1.60.5-0.1-0.6-0.6-1.5-0.60.20.00.00.0-0.20.2-0.2-0.6-0.5-0.40.70.6-1.9
Time in closed arm before self-admin0.10.20.8-0.80.7-0.3-0.10.20.20.60.10.10.6-0.0-0.10.1-0.10.10.0-0.1-0.10.4-0.90.3
Time in closed arm after self-admin0.40.42.0-1.10.2-0.50.60.40.3-0.50.2-0.70.90.60.70.4-0.40.4-0.00.10.11.40.6-1.0
Time in open arm before self-admin0.60.72.21.5-0.71.0-0.8-0.8-0.8-0.6-0.80.7-1.2-0.9-0.8-0.70.7-0.6-0.6-0.4-0.5-1.4-0.10.4
Time in open arm after self-admin1.41.53.31.6-0.91.2-1.4-1.2-1.1-0.2-1.01.5-1.6-1.4-1.3-1.21.2-1.2-0.8-0.9-1.0-1.8-1.40.8
Bone: periosteal estimation1.12.24.01.9-2.01.7-1.4-1.7-1.7-2.0-1.61.3-1.2-1.3-1.2-1.41.4-1.4-1.6-1.6-1.5-0.7-0.6-1.3
Bone: periosteal perimeter0.40.71.21.1-0.81.0-0.9-0.9-0.9-0.6-0.90.9-0.7-0.8-0.7-0.90.9-0.8-0.8-0.9-0.8-0.9-0.7-0.1
Bone: post-yield work1.21.84.82.2-1.61.7-1.3-1.5-1.5-1.0-1.41.2-1.3-1.4-1.4-1.11.1-1.1-1.1-1.1-1.0-1.8-0.5-0.1
Progressive ratio test 1 active lever presses0.70.84.6-0.41.00.2-1.0-0.2-0.11.0-0.20.9-0.8-0.8-0.8-0.70.7-0.6-0.1-0.3-0.5-1.3-1.92.2
Progressive ratio test 1 breakpoint0.70.84.0-0.30.90.2-1.0-0.3-0.20.8-0.20.9-0.8-0.9-0.8-0.80.8-0.7-0.2-0.4-0.6-1.3-1.92.0
Progressive ratio test 1 inactive lever presses1.11.64.61.3-0.21.2-1.5-1.1-1.00.1-1.01.6-1.4-1.4-1.4-1.21.2-1.1-0.7-0.8-1.0-2.2-1.71.5
Progressive ratio test 2 active lever presses0.50.65.1-0.41.3-0.2-0.40.20.21.30.20.3-0.5-0.6-0.6-0.20.2-0.10.40.20.0-1.3-1.22.3
Progressive ratio test 2 breakpoint0.60.65.3-0.51.3-0.2-0.40.20.31.40.30.2-0.4-0.6-0.5-0.10.1-0.10.40.20.1-1.3-1.12.3
Progressive ratio test 2 inactive lever presses0.50.81.90.6-0.20.7-1.1-0.7-0.7-0.4-0.81.1-1.0-1.2-1.3-1.01.0-0.9-0.7-1.0-0.9-0.9-1.40.6
Incentive Sensitization - Responses0.20.31.8-0.41.0-0.40.20.50.51.00.5-0.30.1-0.2-0.10.3-0.30.40.60.50.4-0.6-0.01.4
Incentive Sensitization - Breakpoint0.20.31.9-0.51.0-0.40.20.50.51.10.5-0.30.1-0.2-0.10.3-0.30.30.60.50.4-0.6-0.11.4
Sum of active levers in priming session hrs 5-62.01.95.2-0.92.0-1.41.11.61.52.31.5-1.10.51.01.01.1-1.11.11.61.51.5-0.40.12.3
Progressive ratio0.00.00.30.3-0.1-0.0-0.1-0.10.00.00.1-0.10.10.00.00.1-0.10.10.10.10.0-0.2-0.60.1
Food seeking constrained by brief footshock9.011.015.43.4-2.43.6-3.9-3.5-3.4-1.5-3.33.7-3.7-3.9-3.9-3.53.5-3.4-3.0-3.0-3.2-3.5-3.90.6
Seeking ratio, punishment vs. effort2.02.83.91.6-1.31.8-1.9-1.7-1.8-1.0-1.81.9-2.0-1.9-1.9-1.91.9-1.8-1.7-1.6-1.7-1.5-1.4-0.0
Retroperitoneal fat weight0.52.33.3-1.60.9-1.61.81.51.50.81.5-1.71.71.81.81.7-1.71.61.41.31.51.51.7-0.3
Reaction time number correct0.20.30.70.5-0.30.6-0.5-0.5-0.50.3-0.50.5-0.8-0.7-0.8-0.50.5-0.5-0.4-0.6-0.4-0.9-0.40.6
Reaction time mean minus median0.41.07.50.5-1.50.20.0-0.4-0.4-2.3-0.5-0.20.00.00.1-0.00.1-0.2-0.8-0.5-0.41.9-0.3-2.7
Reaction time mean minus median AUC0.51.25.81.0-1.80.7-0.5-0.9-0.9-2.4-0.90.3-0.6-0.5-0.5-0.50.5-0.6-1.1-0.9-0.71.1-0.7-2.4
Reaction time num false alarms0.10.10.90.1-0.6-0.00.2-0.1-0.0-0.7-0.10.10.10.20.2-0.00.0-0.0-0.1-0.20.00.60.1-1.0
Reaction time num false alarms AUC0.30.51.00.7-1.00.6-0.6-0.7-0.7-1.0-0.70.8-0.6-0.4-0.5-0.70.7-0.7-0.6-0.8-0.6-0.2-0.8-0.6
Reaction time trials correct on left0.20.30.70.5-0.30.6-0.5-0.5-0.50.3-0.50.5-0.8-0.7-0.8-0.50.5-0.5-0.4-0.6-0.4-0.9-0.40.6
Reaction time trials on left0.10.20.60.4-0.20.5-0.4-0.4-0.40.4-0.40.4-0.7-0.6-0.7-0.40.4-0.4-0.3-0.5-0.3-0.8-0.30.6
Reaction time mean2.03.17.4-1.60.8-1.82.11.71.7-0.51.6-2.22.01.91.92.0-2.01.91.31.51.62.71.5-1.6
Reaction time mean AUC2.13.37.9-1.70.8-1.92.11.81.7-0.51.7-2.22.02.02.02.0-2.01.91.41.51.72.81.6-1.6
Median of all reaction times3.85.37.6-2.31.8-2.52.62.42.40.62.4-2.82.52.52.42.6-2.62.52.12.32.32.52.1-0.6
Reaction time omissions2.02.94.0-1.41.6-1.91.81.91.91.01.9-1.91.81.81.82.0-2.02.01.91.91.91.01.10.5
Reaction time false alarm rate0.10.10.6-0.2-0.3-0.20.20.10.2-0.70.1-0.00.30.40.40.1-0.10.10.10.00.10.7-0.2-0.8
Reaction time premature initiation rate1.01.44.4-2.11.6-1.61.11.41.30.61.2-0.91.31.11.10.9-0.90.80.90.90.81.90.0-0.1
Reaction time premature initiations0.40.62.7-1.71.3-1.10.71.00.90.80.8-0.50.70.50.60.5-0.50.40.60.50.51.2-0.30.3
Std. dev. reaction times0.71.25.0-0.3-0.5-0.81.10.60.6-1.50.6-1.21.11.21.21.0-1.00.90.30.60.72.20.8-2.2
Reaction time trials completed0.10.20.60.4-0.20.5-0.4-0.4-0.40.4-0.40.4-0.7-0.6-0.7-0.40.4-0.4-0.3-0.5-0.3-0.8-0.30.6
Reaction time trials AUC0.10.20.60.4-0.20.5-0.4-0.4-0.40.4-0.40.4-0.7-0.6-0.7-0.40.4-0.4-0.4-0.5-0.3-0.8-0.30.6
Run reversals in cocaine runway, females0.20.21.00.8-0.1-0.10.20.10.0-1.0-0.0-0.50.50.10.10.2-0.20.2-0.2-0.00.00.9-0.1-1.0
Run reversals in cocaine runway, males0.00.00.2-0.40.1-0.10.1-0.00.10.20.0-0.0-0.20.00.10.0-0.0-0.00.0-0.00.00.1-0.10.1
Latency to leave start box in cocaine runway0.60.71.10.5-0.80.9-0.8-0.9-1.0-0.8-1.00.7-1.1-0.8-0.8-0.90.9-1.0-1.0-1.0-0.9-0.2-0.7-0.6
Latency to leave start box in cocaine runway, F0.10.10.4-0.60.4-0.10.10.10.10.60.1-0.1-0.3-0.1-0.10.1-0.10.10.10.10.1-0.3-0.20.6
Latency to leave start box in cocaine runway, M1.71.62.01.4-1.11.4-1.4-1.4-1.4-1.2-1.41.3-1.3-1.0-1.1-1.41.4-1.4-1.4-1.2-1.3-0.8-1.0-0.6
Std. dev. time between licks in bursts0.50.71.0-0.60.7-0.80.90.80.90.50.9-1.00.90.90.91.0-1.01.00.90.60.90.61.00.0
Total sessions with >9 infusions0.50.62.90.20.50.4-0.8-0.3-0.30.8-0.30.8-0.8-0.8-0.7-0.60.6-0.5-0.1-0.3-0.4-1.4-1.21.7
Short access day 1 total inactive lever presses1.21.63.31.10.11.1-1.6-1.0-1.00.0-1.01.6-1.6-1.5-1.5-1.41.4-1.4-0.9-1.1-1.2-1.6-1.81.3
Short access day 10 total inactive lever presses0.30.71.01.0-0.70.9-0.9-0.9-0.9-0.8-0.90.9-0.9-0.6-0.5-1.01.0-1.0-0.9-0.8-1.0-0.3-0.6-0.6
Short access day 1 total infusions0.60.83.60.40.70.5-1.0-0.4-0.40.7-0.31.0-1.1-0.9-0.9-0.70.7-0.7-0.1-0.4-0.5-1.7-1.31.9
Short access day 10 total infusions0.50.63.70.20.90.2-0.7-0.1-0.10.9-0.10.6-0.8-0.8-0.7-0.50.5-0.40.0-0.1-0.2-1.4-1.21.9
Short access total infusions0.50.75.0-0.21.10.1-0.60.00.01.20.00.6-0.7-0.7-0.6-0.40.4-0.30.20.0-0.1-1.5-1.12.2
Short access day 1 locomotion0.60.72.5-1.01.4-0.90.50.90.91.50.8-0.50.50.60.60.6-0.60.60.90.60.7-0.2-0.71.6
Short access day 10 total locomotion0.30.61.6-1.30.7-0.90.70.80.80.70.7-0.60.90.91.00.7-0.70.70.60.30.51.0-0.1-0.1
Short access total locomotion0.20.31.5-0.21.0-0.30.00.40.41.00.30.20.20.10.20.2-0.20.20.40.10.2-0.5-1.01.2
One hour access (0.3 mA shock)0.80.91.80.4-0.20.9-1.2-0.8-0.80.0-0.81.1-1.2-1.1-1.0-1.11.1-1.1-0.7-0.7-0.9-1.3-1.01.0
Compulsive drug intake0.20.31.8-0.2-1.30.30.1-0.5-0.4-0.8-0.4-0.1-0.10.10.1-0.20.2-0.3-0.4-0.2-0.30.60.6-1.3
One hour access (shock baseline)0.81.24.20.30.60.7-1.3-0.7-0.60.7-0.61.3-1.1-1.3-1.3-1.01.0-0.9-0.4-0.6-0.8-1.9-1.62.0
Social response proportion4.45.08.3-1.71.3-2.32.62.22.30.82.3-2.52.52.62.62.5-2.52.52.12.12.32.12.9-0.5
Social responses0.20.31.11.1-1.00.6-0.4-0.6-0.6-0.9-0.50.3-0.3-0.3-0.2-0.30.3-0.3-0.5-0.6-0.3-0.20.2-0.8
Social time1.72.36.90.10.5-1.21.81.31.30.61.5-1.91.61.61.61.9-1.91.91.61.71.90.52.6-0.1
Soleus weight0.51.45.70.50.8-0.30.70.80.71.81.0-0.30.50.60.71.0-1.01.11.41.31.4-2.21.22.4
Bone: stiffness1.52.58.22.6-2.91.8-1.0-1.7-1.8-2.4-1.71.2-1.0-1.1-1.1-1.01.0-1.1-1.5-1.4-1.1-0.70.4-2.0
Tibialis anterior weight6.321.530.85.5-4.65.3-5.0-5.1-5.1-3.9-4.95.0-4.9-4.8-4.9-4.84.8-4.7-4.5-4.4-4.5-4.2-3.5-1.0
Time to tail flick, vehicle, before self-admin0.20.22.2-1.50.3-0.30.10.20.20.10.1-0.20.40.20.10.0-0.00.0-0.0-0.2-0.20.6-0.3-0.1
Time to tail flick, vehicle, after self-admin0.20.21.2-1.1-0.30.3-0.4-0.4-0.4-0.3-0.40.7-0.3-0.5-0.4-0.30.3-0.3-0.5-0.7-0.50.00.0-0.3
Time to tail flick, test, before self-admin0.60.61.30.9-0.60.8-1.1-1.0-0.8-0.7-0.80.8-0.6-0.7-0.6-0.90.9-0.8-0.8-0.8-1.0-0.4-1.2-0.3
Time to tail flick, test, after self-admin3.33.55.81.4-2.01.7-1.8-2.0-1.9-2.4-2.01.8-1.6-1.4-1.3-2.02.0-2.0-2.2-2.2-2.10.3-1.8-2.0
Delta time to tail flick, vehicle, before/after SA0.10.10.50.4-0.40.10.2-0.0-0.0-0.30.00.10.20.10.20.3-0.30.30.10.10.3-0.10.7-0.3
Delta time to tail flick, test, before/after SA0.20.21.0-0.4-0.50.00.1-0.1-0.2-0.6-0.30.2-0.0-0.0-0.0-0.20.2-0.3-0.4-0.5-0.30.9-0.1-1.0
Tibia length0.51.44.7-0.10.7-0.61.11.00.91.31.1-1.01.01.01.01.2-1.21.31.41.51.5-1.02.21.3
Ambulatory time before self-admin1.62.34.31.3-1.41.8-1.5-1.6-1.7-0.8-1.61.7-2.0-1.8-1.8-1.61.6-1.6-1.3-1.3-1.4-2.1-0.80.4
Ambulatory time after self-admin0.10.10.60.6-0.70.40.2-0.2-0.3-0.3-0.30.3-0.6-0.3-0.4-0.10.1-0.1-0.2-0.30.1-0.40.8-0.2
Bone: tissue strength0.60.62.60.2-0.6-0.40.90.40.4-0.30.5-1.00.80.80.80.8-0.80.80.50.90.80.41.6-0.8
Total heroin consumption1.01.25.8-0.81.5-0.90.51.01.12.01.1-0.60.30.70.70.8-0.80.81.31.11.1-1.0-0.02.4
Bone: trabecular number1.11.93.41.4-1.81.3-1.2-1.4-1.4-1.9-1.51.2-1.2-1.4-1.4-1.31.3-1.3-1.5-1.6-1.3-0.1-1.1-1.4
Bone: trabecular spacing0.00.10.3-0.10.1-0.10.10.10.1-0.40.0-0.20.20.30.30.1-0.10.0-0.1-0.0-0.10.60.1-0.5
Bone: trabecular thickness0.00.10.3-0.3-0.1-0.30.30.20.2-0.10.2-0.20.10.20.10.2-0.20.20.10.10.20.50.1-0.4
Bone: trabecular tissue density0.81.24.92.2-2.01.4-0.8-1.3-1.3-1.4-1.10.9-0.7-0.6-0.6-0.70.7-0.7-0.9-0.9-0.7-1.10.6-1.0
Water consumed over 24 hours1.11.52.40.8-1.31.2-1.4-1.2-1.3-1.3-1.31.3-1.2-1.2-1.2-1.41.4-1.4-1.4-1.2-1.5-0.3-1.5-0.6
Number of responses in last shaping day0.91.07.7-0.21.4-0.2-0.00.50.42.10.5-0.1-0.3-0.2-0.20.2-0.20.30.80.90.6-2.0-0.12.8