Hub : Genes

Reck

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Reck 0.12 0.07 5.8e-13 0.09 0.08 0.09 0.08 2.6e-10 6.9e-09 6.8e-10 4.7e-09
2 RMTg mRNA stability Reck 0.09 0.07 1.0e-02 0.13 0.03 0.09 0.11 2.3e-04 4.6e-02 2.2e-03 7.5e-04
3 IC gene expression Reck 0.31 0.15 1.8e-09 0.22 0.21 0.21 0.22 7.6e-10 2.6e-09 2.5e-09 1.5e-09
4 Adipose isoform ratio XM_063287725.1 0.03 0.02 3.2e-04 0.02 0.02 0.02 0.02 5.6e-03 1.4e-03 2.2e-03 1.7e-03
5 PL gene expression Reck 0.3 0.09 0.0e+00 0.43 0.46 0.46 0.46 1.4e-50 1.9e-55 2.4e-55 1.4e-55
6 Adipose isoform ratio NM_001415923.1 0.02 0.02 1.6e-03 0.02 0.02 0.02 0.02 1.8e-03 1.4e-03 2.2e-03 2.1e-03
7 IL mRNA stability Reck 0.13 0.09 6.1e-03 0.07 0.01 0.2 0.07 1.1e-02 1.8e-01 1.8e-05 1.1e-02
8 OFC gene expression Reck 0.5 0.19 2.2e-09 0.31 0.32 0.33 0.33 3.7e-08 2.5e-08 9.9e-09 1.1e-08
9 NAcc mRNA stability Reck 0.02 0.01 1.8e-03 0.02 0.02 0.01 0.01 1.2e-03 3.5e-04 2.7e-03 1.8e-03
10 RMTg gene expression Reck 0.19 0.11 6.7e-05 0.13 0.14 0.14 0.14 2.7e-04 2.0e-04 1.2e-04 1.2e-04
11 Adipose alternative TSS XM_063287725.1 0.13 0.07 0.0e+00 0.15 0.15 0.15 0.15 1.9e-16 2.6e-16 2.9e-16 3.3e-16
12 Brain mRNA stability Reck 0.07 0.05 1.9e-06 0.08 0.07 0.07 0.08 5.0e-08 3.2e-07 4.0e-07 7.2e-08
13 BLA gene expression Reck 0.37 0.16 2.2e-13 0.25 0.22 0.22 0.23 2.1e-13 3.9e-12 7.5e-12 2.3e-12
14 pVTA gene expression Reck 0.14 0.09 5.6e-06 0.07 0.04 0.05 0.06 1.9e-06 4.8e-04 1.0e-04 9.7e-06
15 Adipose alternative TSS NM_001415923.1 0.21 0.1 0.0e+00 0.25 0.25 0.25 0.26 7.1e-28 1.0e-27 5.5e-28 4.4e-28
16 Adipose alternative TSS XM_063287725.1 0.21 0.1 0.0e+00 0.26 0.25 0.26 0.26 3.8e-28 5.2e-28 3.1e-28 2.2e-28
17 Adipose alternative TSS NM_001415923.1 0.21 0.1 0.0e+00 0.25 0.25 0.25 0.25 1.6e-27 1.2e-27 6.0e-28 5.1e-28
18 Brain gene expression Reck 0.34 0.12 0.0e+00 0.4 0.43 0.43 0.42 1.6e-39 1.6e-43 1.7e-43 1.4e-42
19 NAcc gene expression Reck 0.26 0.09 0.0e+00 0.3 0.3 0.32 0.31 1.9e-46 1.1e-46 9.0e-49 1.4e-48
20 IL gene expression Reck 0.51 0.16 2.1e-13 0.47 0.52 0.52 0.52 1.0e-12 2.1e-14 8.6e-15 1.4e-14
21 PL mRNA stability Reck 0.05 0.04 2.0e-03 0.01 0.03 0.03 0.03 4.5e-02 2.9e-04 3.8e-04 4.8e-04
22 LHb gene expression Reck 0.32 0.19 1.0e-03 0.11 0.11 0.16 0.12 1.2e-03 1.3e-03 1.1e-04 7.8e-04
23 Liver gene expression Reck 0.17 0.09 2.1e-13 0.06 0.11 0.1 0.11 3.9e-07 2.4e-12 1.0e-10 9.4e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density1.63.04.2-1.51.51.91.7-1.8-1.82.02.0-1.8-1.6-1.71.71.81.8-1.81.8-1.8-1.91.81.8-0.21.7-1.4
Area under the delay curve0.30.51.60.7-0.7-0.6-0.70.60.8-1.3-0.40.80.30.6-0.6-0.7-0.60.6-0.60.61.0-0.8-0.7-0.20.10.9
BMI with tail2.17.39.8-2.42.42.62.8-3.0-2.92.52.9-2.9-3.0-2.82.82.72.7-2.92.9-2.9-3.03.13.0-1.12.6-1.3
BMI without tail1.26.57.8-2.72.72.72.8-2.8-2.82.62.4-2.8-2.7-2.72.52.52.6-2.62.6-2.6-2.72.72.7-1.42.1-1.3
Body weight3.214.017.4-4.04.03.64.2-4.1-4.03.03.6-3.9-4.2-4.13.83.93.9-3.93.9-3.8-3.73.73.8-3.33.4-0.6
Weight adjusted by age0.20.51.2-0.60.60.10.6-0.7-0.60.10.8-0.5-1.1-0.80.90.90.9-0.80.8-0.8-0.40.40.6-1.10.70.7
Bone surface0.91.82.3-1.31.31.21.4-1.4-1.41.31.5-1.4-1.4-1.51.41.51.5-1.41.4-1.4-1.41.51.4-0.81.3-0.5
Bone volume0.81.72.3-1.01.01.31.3-1.3-1.31.51.5-1.4-1.2-1.31.31.41.4-1.41.4-1.4-1.41.41.4-0.31.4-0.8
Breakpoint value in progressive ratio session0.71.210.70.0-0.0-1.6-0.50.70.8-2.1-0.00.90.1-0.00.3-0.0-0.10.2-0.30.41.3-1.1-0.9-2.20.13.3
Number of licking bursts1.75.17.1-2.32.32.52.4-2.4-2.52.71.9-2.5-2.2-2.02.42.42.4-2.32.3-2.3-2.52.32.4-0.81.8-1.6
Context. condit. distance diff. score0.00.00.20.3-0.3-0.3-0.20.20.10.00.00.10.10.00.0-0.1-0.0-0.00.0-0.0-0.0-0.1-0.00.40.1-0.1
Locomotion velocity, session 11.21.49.4-1.21.2-0.40.9-0.5-0.6-1.40.7-0.4-1.1-1.00.91.11.0-0.70.7-0.60.00.50.3-3.11.02.7
Locomotion distance, session 10.30.42.8-0.80.80.10.6-0.3-0.4-0.70.4-0.3-0.5-0.50.50.50.5-0.40.4-0.30.00.40.2-1.70.31.3
Locomotion velocity, session 22.32.84.9-1.71.72.11.7-1.8-1.82.01.8-1.8-1.6-1.71.41.51.3-1.71.7-1.7-1.82.21.7-0.41.2-1.5
Locomotion distance, session 20.71.03.4-1.81.81.51.3-1.1-1.00.50.3-0.9-0.9-0.70.80.80.8-0.70.7-0.6-0.60.90.5-1.7-0.10.1
Locomotion velocity, session 30.20.21.7-0.40.4-0.20.2-0.0-0.1-0.80.1-0.0-0.2-0.30.30.30.3-0.10.1-0.00.20.0-0.1-1.30.21.3
Locomotion distance, session 33.43.95.8-1.71.71.22.1-2.0-2.00.92.1-2.0-2.2-2.32.32.32.4-2.22.2-2.1-1.82.02.0-2.02.30.5
Stereotopy head waving bouts, day 30.60.72.4-0.00.0-0.7-0.40.60.6-1.5-1.10.70.40.7-0.4-0.5-0.40.7-0.70.71.0-1.2-0.9-1.1-0.91.6
Stereotopy head waving duration, day 30.60.71.60.3-0.3-0.8-0.70.80.8-1.1-1.30.80.71.0-0.7-0.6-0.60.9-0.91.01.0-1.3-1.0-0.4-0.91.0
Locomotion velocity, session 70.10.10.10.3-0.3-0.2-0.30.30.3-0.30.00.30.30.2-0.3-0.3-0.40.3-0.30.30.3-0.2-0.30.2-0.10.2
Locomotion distance, session 70.30.30.7-0.60.60.40.6-0.5-0.50.20.9-0.5-0.6-0.80.60.60.5-0.60.6-0.6-0.40.50.5-0.70.70.3
Stereotopy head waving bouts, day 71.72.03.2-1.41.40.81.6-1.5-1.50.51.3-1.5-1.7-1.41.71.71.8-1.51.5-1.5-1.41.11.4-1.61.40.4
Stereotopy head waving duration, day 70.40.51.0-1.01.00.50.9-0.8-0.80.30.3-0.7-0.8-0.60.80.90.9-0.60.6-0.5-0.60.40.6-1.00.30.2
Locomotion velocity, session 80.50.61.9-0.30.3-0.3-0.40.60.6-0.9-1.10.70.80.5-0.7-0.7-0.70.9-0.90.91.0-0.8-1.1-0.8-1.40.9
Locomotion distance, session 80.10.11.2-0.70.70.10.3-0.1-0.1-0.4-0.2-0.0-0.1-0.30.10.20.1-0.00.0-0.00.2-0.0-0.2-1.1-0.40.8
Degree of sensitization distance2.22.44.01.0-1.0-0.9-1.61.61.6-0.9-1.61.61.81.7-1.9-1.8-2.01.7-1.71.71.6-1.7-1.71.1-1.8-0.0
Degree of sensitization stereotypy2.32.63.7-1.21.21.01.7-1.7-1.71.01.8-1.7-1.9-1.71.81.91.9-1.71.7-1.7-1.71.61.8-1.11.8-0.1
Conditioned locomotion0.40.41.9-0.10.1-0.40.4-0.3-0.3-0.80.9-0.3-0.6-0.70.70.70.7-0.50.5-0.5-0.10.40.3-1.21.11.4
Cocaine response after cond. corrected1.21.84.91.3-1.3-2.0-1.21.41.3-2.2-1.11.41.00.9-0.9-0.9-0.91.2-1.21.21.5-1.3-1.4-0.5-0.82.1
Cocaine response after cond. not corrected1.62.35.41.1-1.1-1.9-1.31.61.5-2.3-1.61.61.31.1-1.2-1.2-1.21.5-1.51.51.8-1.7-1.7-0.7-1.42.1
Cocaine response before conditioning0.20.20.8-0.90.90.90.5-0.5-0.50.8-0.2-0.4-0.2-0.20.20.20.2-0.20.2-0.2-0.30.00.3-0.2-0.4-0.7
Saline control response0.40.52.2-1.01.00.40.9-0.7-0.70.00.3-0.6-0.8-0.90.70.70.7-0.50.5-0.5-0.40.30.5-1.50.40.7
Bone: connectivity density1.11.83.1-1.11.11.61.2-1.4-1.31.61.8-1.4-1.2-1.21.21.41.4-1.21.3-1.3-1.51.51.40.11.4-1.2
Bone: cortical apparent density0.20.22.00.2-0.20.5-0.20.00.10.90.1-0.00.30.2-0.3-0.4-0.40.1-0.10.1-0.20.20.01.3-0.4-1.4
Bone: cortical area1.93.17.0-1.61.62.31.7-1.9-1.92.61.5-1.9-1.5-1.51.51.41.4-1.71.7-1.7-2.12.11.80.21.1-2.2
Bone: cortical porosity0.10.20.20.2-0.2-0.3-0.40.40.4-0.3-0.50.40.50.5-0.3-0.4-0.30.5-0.50.50.4-0.5-0.50.3-0.30.0
Bone: cortical porosity0.10.10.2-0.20.2-0.00.2-0.1-0.20.00.1-0.2-0.2-0.20.40.30.4-0.20.2-0.2-0.20.10.2-0.30.40.2
Bone: cortical thickness1.01.74.5-0.50.51.51.0-1.3-1.32.11.3-1.4-1.0-1.01.11.01.0-1.21.3-1.3-1.61.61.41.01.0-2.1
Bone: cortical thickness0.30.41.50.7-0.7-0.5-0.70.60.60.2-0.60.50.60.5-0.7-0.7-0.70.5-0.50.50.4-0.0-0.51.2-0.7-0.7
Bone: cortical tissue density0.10.21.60.2-0.20.4-0.30.10.10.70.00.10.40.3-0.4-0.4-0.40.2-0.20.2-0.10.1-0.11.3-0.4-1.2
Condit. Reinf. active minus inactive responses0.30.30.7-0.90.90.70.6-0.5-0.60.70.2-0.6-0.3-0.40.50.40.4-0.40.4-0.4-0.60.70.4-0.2-0.2-0.7
Condit. Reinf. active-inactive response ratio0.60.70.90.9-0.9-0.9-0.90.90.9-0.5-0.90.80.90.9-0.8-0.8-0.80.9-0.90.90.8-0.7-0.80.8-0.80.1
Condit. Reinf. active responses1.92.44.4-2.12.12.01.7-1.7-1.71.91.1-1.7-1.3-1.41.51.41.4-1.41.4-1.4-1.61.71.4-0.70.5-1.4
Condit. Reinf. inactive responses2.02.65.6-2.22.22.41.8-1.8-1.82.31.0-1.8-1.4-1.21.21.41.4-1.41.4-1.4-1.71.61.5-0.40.5-1.9
Incentive salience index mean3.34.27.2-2.72.72.32.4-2.3-2.32.01.7-2.2-1.9-2.02.12.02.1-2.02.0-2.0-2.12.11.9-1.51.2-1.1
Condit. Reinf. lever presses8.112.119.5-4.44.43.84.0-3.8-3.82.93.1-3.7-3.5-3.43.63.53.5-3.53.5-3.5-3.43.33.3-3.02.6-1.0
Condit. Reinf. active minus inactive responses0.60.91.3-0.70.71.10.9-1.0-1.01.11.2-1.0-0.9-1.10.80.80.8-1.01.0-1.0-1.11.11.10.00.7-0.9
Condit. Reinf. active-inactive response ratio0.20.40.8-0.10.10.60.4-0.5-0.60.80.9-0.6-0.6-0.60.50.40.4-0.60.7-0.7-0.80.80.80.50.6-0.8
Condit. Reinf. active responses1.82.53.9-1.71.72.01.7-1.7-1.71.71.7-1.7-1.5-1.81.41.41.4-1.61.6-1.7-1.71.61.7-0.71.1-1.1
Condit. Reinf. inactive responses1.62.44.9-1.91.92.21.7-1.7-1.71.91.4-1.7-1.4-1.51.31.31.3-1.51.5-1.5-1.61.51.5-0.60.9-1.4
Condit. Reinf. lever presses1.92.76.5-1.71.72.51.6-1.8-1.72.41.6-1.8-1.4-1.51.21.21.2-1.41.4-1.5-1.91.71.70.20.7-2.3
Condit. Reinf. lever reinforcers received1.92.74.7-1.91.92.21.8-1.8-1.81.81.7-1.8-1.6-1.81.51.51.5-1.61.6-1.6-1.71.71.7-0.71.0-1.3
Conditioned reinforcement - actives0.10.51.7-0.10.10.20.5-0.6-0.5-0.11.3-0.6-0.8-0.70.90.80.7-0.80.8-0.8-0.50.70.7-0.70.90.5
Conditioned reinforcement - inactives0.10.20.80.1-0.1-0.7-0.40.30.4-0.80.50.4-0.1-0.20.0-0.1-0.3-0.00.0-0.00.4-0.2-0.1-0.20.50.9
Conditioned locomotion0.91.35.0-0.00.0-0.10.8-0.8-0.8-0.21.9-0.9-1.4-1.41.21.11.0-1.31.3-1.3-0.81.21.2-1.02.20.9
Patch foraging indifference point 0 sec1.13.19.1-1.31.30.11.4-1.3-1.3-0.72.2-1.2-2.1-1.92.01.91.9-1.81.8-1.7-0.90.81.5-2.83.02.3
Patch foraging indifference point AUC4.210.013.1-3.63.63.23.6-3.4-3.52.93.0-3.4-3.3-3.53.13.23.2-3.33.3-3.2-3.13.23.2-2.52.5-1.1
Delay disc. indifference point, 0s delay1.11.22.10.7-0.7-1.5-1.11.11.2-1.4-1.21.21.01.0-1.0-1.2-1.30.9-1.01.01.4-1.2-1.2-0.1-0.71.2
Delay disc. indifference point, 16s delay0.60.83.70.8-0.8-1.2-0.80.90.9-1.7-0.21.00.20.5-0.6-0.4-0.20.6-0.60.71.2-0.9-0.8-0.80.61.9
Delay disc. indifference point, 2s delay0.10.10.4-0.20.20.20.2-0.3-0.20.40.1-0.2-0.4-0.00.20.10.1-0.20.2-0.3-0.30.30.40.40.6-0.6
Delay disc. indifference point, 24s delay0.10.20.50.1-0.1-0.1-0.50.50.5-0.2-0.60.60.40.7-0.6-0.6-0.50.6-0.60.60.6-0.5-0.60.3-0.4-0.0
Delay disc. indifference point, 4s delay0.10.10.90.9-0.9-0.1-0.30.20.3-0.6-0.30.40.10.3-0.3-0.3-0.20.2-0.20.20.4-0.2-0.3-0.1-0.00.3
Delay disc. indifference point, 8s delay0.00.00.3-0.20.20.5-0.0-0.10.1-0.00.20.1-0.20.1-0.2-0.3-0.20.0-0.00.00.2-0.10.0-0.10.2-0.2
Indifference point function ln k1.03.14.61.9-1.9-2.1-2.01.92.0-2.0-1.71.91.72.0-1.6-1.7-1.71.7-1.71.71.9-1.9-1.81.0-1.11.2
Indifference point function log k1.03.14.61.9-1.9-2.1-2.01.92.0-2.0-1.71.91.72.0-1.6-1.7-1.71.7-1.71.71.9-1.9-1.81.0-1.11.2
Patch foraging total patch changes 0 sec1.44.110.6-1.71.70.51.8-1.7-1.7-0.32.5-1.6-2.5-2.22.42.32.3-2.12.1-2.0-1.41.21.9-2.83.32.0
Patch foraging total patch changes 12 sec3.75.07.5-1.91.91.82.3-2.4-2.31.82.6-2.3-2.5-2.62.42.42.4-2.42.4-2.4-2.32.12.4-1.42.7-0.4
Patch foraging total patch changes 18 sec0.41.01.4-1.21.21.01.1-1.0-1.00.81.1-1.0-1.1-1.20.90.90.9-1.01.0-1.0-0.90.81.0-1.01.1-0.1
Patch foraging total patch changes 24 sec1.44.86.5-2.02.01.72.4-2.2-2.31.22.5-2.3-2.5-2.62.52.32.4-2.42.4-2.4-2.12.12.3-2.02.10.1
Patch foraging total patch changes 6 sec4.16.910.8-2.52.51.82.7-2.7-2.61.03.1-2.6-3.0-3.02.92.92.9-2.82.8-2.7-2.32.32.6-2.93.30.8
Patch foraging time to switch 0 sec1.45.26.92.4-2.4-1.6-2.52.42.4-1.2-2.32.32.62.6-2.5-2.6-2.52.5-2.52.42.1-2.2-2.32.3-2.0-0.2
Patch foraging water rate 0 sec1.76.39.6-1.81.81.22.5-2.4-2.50.83.1-2.5-3.0-3.02.92.93.0-2.92.8-2.8-2.32.52.7-2.43.10.8
Patch foraging water rate 12 sec0.00.10.60.2-0.2-0.20.3-0.2-0.2-0.70.2-0.2-0.4-0.40.50.40.4-0.30.3-0.3-0.10.30.2-0.7-0.10.8
Patch foraging water rate 18 sec0.71.62.8-0.40.40.61.1-1.2-1.21.01.7-1.3-1.3-1.41.61.51.4-1.51.5-1.5-1.51.61.50.01.2-0.6
Patch foraging water rate 24 sec0.20.31.00.2-0.20.30.1-0.2-0.30.80.9-0.4-0.3-0.30.40.30.3-0.40.5-0.5-0.60.80.61.00.6-1.0
Patch foraging water rate 6 sec0.40.51.4-0.60.60.40.9-0.7-0.90.50.3-0.9-0.7-0.81.21.00.9-0.70.7-0.7-0.80.80.7-0.6-0.1-0.0
Seeking ratio, delayed vs. immediate footshock4.05.79.6-1.51.52.62.4-2.7-2.52.13.1-2.5-2.8-2.52.42.32.3-2.72.7-2.7-2.52.52.7-1.22.5-1.1
Distance traveled before self-admin1.12.34.2-1.41.41.51.9-1.6-1.80.91.2-1.6-1.6-1.71.91.81.9-1.61.6-1.5-1.41.31.3-2.00.60.2
Distance traveled after self-admin0.30.42.1-0.70.71.40.6-0.5-0.71.10.2-0.60.1-0.40.50.40.5-0.30.3-0.3-0.70.70.30.3-0.6-1.4
Extensor digitorum longus weight4.819.324.5-4.94.94.54.8-4.7-4.73.94.5-4.6-4.5-4.74.64.54.4-4.64.6-4.5-4.44.44.4-3.14.0-1.5
Bone: elastic displacement3.03.88.12.8-2.8-2.4-2.32.22.1-1.4-1.42.01.91.9-1.9-2.0-1.91.8-1.81.81.7-1.7-1.62.3-0.90.3
Bone: elastic work1.31.79.22.1-2.1-0.8-1.51.21.20.4-0.41.01.21.1-1.2-1.3-1.20.9-0.90.80.5-0.5-0.63.0-0.3-1.6
Bone: endosteal estimation0.51.33.2-1.81.81.21.5-1.3-1.31.00.6-1.2-1.2-1.10.91.01.0-1.11.1-1.0-1.01.01.0-1.50.5-0.1
Bone: endosteal perimeter0.71.73.2-1.81.81.21.6-1.4-1.40.71.0-1.3-1.4-1.41.31.31.3-1.31.3-1.3-1.11.21.2-1.80.90.2
Epididymis fat weight0.10.71.8-1.21.21.30.9-0.9-0.91.30.2-0.8-0.7-0.80.40.60.6-0.70.7-0.6-0.80.90.7-0.20.2-1.0
Delta time in closed arm before/after self-admin0.40.42.30.1-0.11.20.4-0.5-0.51.40.4-0.6-0.2-0.10.20.10.0-0.30.3-0.4-0.70.60.50.8-0.2-1.5
Delta time in open arm before/after self-admin0.20.31.2-0.00.0-0.4-0.40.40.5-1.10.30.60.2-0.0-0.4-0.3-0.30.4-0.40.50.7-0.6-0.6-0.60.11.0
Diff in mean of infusions in LGA sessions0.30.51.00.1-0.10.1-0.60.80.60.5-0.80.61.01.0-0.8-0.9-0.80.8-0.80.80.5-0.5-0.71.0-0.9-0.8
Delay discount exponential model param0.30.41.4-0.60.60.50.6-0.5-0.71.20.3-0.7-0.2-0.50.50.60.4-0.40.4-0.5-0.80.60.60.3-0.2-0.9
Extinction: sum of active levers before priming2.33.55.21.3-1.3-1.6-2.12.02.2-2.3-1.32.22.02.0-1.6-2.1-2.02.0-2.02.02.3-2.1-2.20.4-1.11.5
Active lever presses in extinction session 60.10.10.40.5-0.5-0.2-0.30.30.3-0.50.40.30.20.1-0.1-0.10.10.1-0.10.10.3-0.1-0.2-0.10.20.6
Bone: final force0.61.03.3-1.51.51.81.1-1.1-1.11.60.2-1.1-0.6-0.70.70.70.7-0.70.7-0.7-1.00.80.7-0.3-0.2-1.3
Bone: final moment0.50.83.0-1.21.21.70.9-0.9-0.91.60.0-0.9-0.4-0.50.50.50.5-0.50.5-0.5-0.90.60.5-0.0-0.4-1.5
Food consumed during 24 hour testing period0.20.30.9-1.01.00.90.8-0.6-0.60.40.3-0.6-0.6-0.60.40.40.4-0.50.5-0.5-0.40.40.4-0.90.1-0.0
Glucose2.74.35.4-2.32.31.92.3-2.3-2.31.71.9-2.2-2.2-2.32.12.22.1-2.22.2-2.2-2.12.22.1-1.61.8-0.6
Heart weight0.30.51.6-1.01.01.30.9-1.0-0.80.70.2-0.8-0.5-0.40.70.70.6-0.50.5-0.5-0.70.60.5-0.6-0.1-0.6
Delay discount hyperbolic model param0.20.21.0-0.50.50.40.4-0.4-0.51.00.1-0.6-0.1-0.40.30.40.3-0.30.3-0.3-0.70.50.40.4-0.3-0.8
Intermittent access intake day 1-15 change0.20.91.7-0.60.60.91.0-1.0-1.11.30.7-1.1-0.9-0.91.10.90.8-1.11.1-1.2-1.21.21.10.10.6-1.0
Intermittent access intake escalation0.10.71.6-0.40.40.80.8-0.8-0.91.30.5-0.9-0.7-0.60.80.60.6-0.90.9-0.9-1.11.00.90.30.2-1.1
Intermittent access intake escalation 20.81.33.6-0.40.41.21.0-1.1-1.21.91.0-1.3-0.9-0.90.90.70.7-1.11.1-1.2-1.51.51.30.80.5-1.9
Intermitt. access day 1 inactive lever presses0.11.53.9-2.02.01.01.2-1.2-1.21.01.3-1.1-1.3-1.41.01.11.1-1.11.1-1.1-1.01.11.1-1.01.4-0.2
Intermitt. access day 15 inactive lever presses0.00.10.50.1-0.10.10.2-0.3-0.1-0.20.4-0.1-0.4-0.50.20.10.2-0.30.3-0.20.00.00.2-0.70.00.5
Intermitt. access escalation Index0.10.31.5-1.21.20.20.6-0.5-0.50.6-0.5-0.5-0.5-0.20.50.40.5-0.50.5-0.5-0.40.10.4-0.60.60.0
Intermittent access day 1 total infusions0.20.75.30.9-0.9-1.4-0.60.50.6-1.70.90.6-0.1-0.1-0.00.20.20.1-0.10.20.7-0.4-0.3-0.91.22.3
Intermittent access day 15 total infusions0.30.72.2-0.00.00.30.6-0.7-0.70.51.5-0.8-1.0-0.90.90.90.9-1.01.0-1.0-0.81.01.0-0.31.50.1
Intermittent access terminal intake (last 3 days)0.61.13.3-0.40.40.20.8-0.8-0.80.71.7-0.9-1.2-1.11.21.21.1-1.21.2-1.2-1.01.11.2-0.51.80.3
Intermittent access total infusions1.11.34.2-0.40.40.10.8-0.9-0.90.21.9-0.9-1.4-1.41.21.41.3-1.31.3-1.2-0.91.11.2-1.02.10.9
Intermittent access day 1 locomotion0.30.63.20.7-0.7-1.2-0.50.40.5-1.41.10.4-0.2-0.3-0.20.10.10.1-0.10.10.5-0.1-0.1-0.61.61.8
Intermittent access day 15 total locomotion0.10.52.51.1-1.1-1.1-0.40.30.4-1.01.10.3-0.4-0.4-0.00.40.3-0.20.2-0.10.30.00.1-0.41.11.6
Intermittent access total locomotion0.30.41.71.3-1.3-1.0-0.60.50.5-0.80.90.40.0-0.1-0.3-0.1-0.20.1-0.10.10.30.10.00.41.10.8
Intermittent access standard deviation0.21.02.0-0.30.30.50.9-1.0-0.90.41.4-1.0-1.1-1.11.31.21.1-1.21.2-1.2-0.91.01.1-0.71.30.1
Left kidney weight0.11.23.9-1.71.71.41.4-1.2-1.10.50.7-1.0-1.0-1.11.10.90.9-1.01.0-0.9-0.70.70.7-2.00.40.5
Right kidney weight0.10.72.9-1.61.61.71.0-0.9-0.91.10.6-0.8-0.5-0.50.40.30.4-0.40.4-0.4-0.70.70.5-0.60.1-0.8
Cocaine induced anxiety0.20.41.00.5-0.5-0.7-0.60.70.7-0.4-1.00.70.60.5-0.7-0.9-0.90.7-0.70.70.6-0.5-0.60.4-0.70.1
Post-drug Anxiety0.10.10.8-0.90.90.30.3-0.1-0.20.0-0.7-0.1-0.1-0.1-0.0-0.2-0.20.1-0.10.10.1-0.1-0.1-0.8-0.50.2
Baseline Anxiety0.20.31.7-1.11.11.30.6-0.7-0.60.70.1-0.5-0.2-0.10.20.20.2-0.20.2-0.2-0.40.20.3-0.3-0.1-0.8
Tail length0.73.77.5-2.72.72.72.3-2.1-2.22.21.4-2.1-1.7-2.01.71.71.7-1.71.7-1.6-1.81.71.7-1.70.6-1.1
Length with tail1.14.78.6-2.92.92.22.6-2.3-2.31.31.9-2.2-2.3-2.52.22.32.2-2.02.0-1.9-1.81.81.9-2.91.60.4
Length without tail0.10.53.2-0.40.4-0.10.6-0.5-0.4-0.80.5-0.3-0.8-0.80.60.60.6-0.50.5-0.5-0.00.20.3-1.80.71.6
Times rat made contact with spout0.60.71.4-0.50.50.90.7-0.8-0.81.21.0-0.9-0.9-0.80.70.70.7-0.90.9-0.9-1.00.81.00.21.1-0.8
Lifetime Intake1.01.23.8-0.20.2-0.20.7-0.8-0.7-0.21.9-0.8-1.3-1.31.31.41.3-1.21.2-1.1-0.70.91.0-1.41.91.4
Liver weight, left0.20.40.8-0.20.2-0.1-0.40.50.5-0.3-0.90.60.60.9-0.7-0.6-0.60.7-0.70.70.7-0.8-0.7-0.1-0.70.2
Liver weight, right0.61.12.11.5-1.5-1.0-1.21.11.1-0.9-0.91.11.10.9-1.2-1.1-1.11.1-1.11.11.0-0.8-1.00.9-0.90.2
Locomotor activity0.00.00.3-0.50.50.2-0.10.10.1-0.0-0.30.20.20.2-0.2-0.1-0.10.1-0.10.20.2-0.1-0.2-0.0-0.2-0.0
Locomotor testing distance0.20.51.4-0.10.1-0.7-0.50.70.7-1.1-0.80.80.50.5-0.5-0.5-0.50.6-0.60.60.9-0.8-0.8-0.6-0.51.2
Locomotor testing rearing0.10.31.7-1.31.30.70.6-0.4-0.50.40.0-0.4-0.4-0.50.30.40.4-0.40.4-0.4-0.20.30.2-0.90.00.0
Locomotion in novel chamber0.20.31.70.8-0.80.1-0.50.40.30.20.10.20.50.5-0.5-0.6-0.50.3-0.20.2-0.0-0.0-0.11.30.3-0.9
Locomotion in novel chamber post-restriction0.41.25.7-0.40.41.81.0-1.0-1.22.40.7-1.2-0.5-0.60.80.60.6-0.80.8-0.9-1.41.30.90.8-0.1-2.2
Fecal boli incidents, locomotor time 10.20.61.30.7-0.7-0.4-1.00.80.9-0.4-0.30.90.70.8-1.1-1.1-1.00.8-0.80.80.8-0.7-0.61.00.0-0.3
Change in fecal boli incidents, locomotor task0.80.81.4-0.90.90.11.0-0.8-0.90.30.5-0.9-1.2-1.10.91.00.9-1.11.1-1.0-0.80.91.0-1.20.70.7
Time >=10cm from walls, locomotor time 10.30.31.4-0.40.4-0.60.3-0.2-0.2-0.6-0.0-0.2-0.5-0.50.70.70.6-0.60.6-0.5-0.10.00.2-1.10.81.2
Bouts of movement, locomotor time 11.62.13.21.3-1.3-1.3-1.61.71.6-1.4-1.51.51.51.6-1.7-1.8-1.41.4-1.41.41.5-1.5-1.51.0-1.20.3
Total resting periods, locomotor time 12.32.74.11.7-1.7-1.3-1.81.91.8-1.2-1.71.71.81.9-1.9-2.0-1.61.6-1.61.61.6-1.6-1.61.6-1.6-0.0
Rest time, locomotor task time 11.72.77.71.5-1.5-0.5-1.61.51.40.2-1.91.32.02.0-1.9-1.9-1.61.6-1.61.51.0-1.1-1.32.8-2.3-1.8
Distance moved, locomotor task time 11.02.86.3-1.61.60.81.8-1.6-1.60.31.7-1.5-2.0-1.92.02.21.9-1.71.7-1.6-1.31.31.4-2.52.01.4
Vertical activity count, locomotor time 10.21.26.3-1.21.20.11.1-0.8-0.9-0.30.3-0.7-1.0-1.01.41.51.5-0.90.9-0.8-0.40.20.4-2.50.91.9
Time >=10cm from walls, locomotor time 20.00.10.4-0.00.00.10.2-0.2-0.2-0.20.0-0.10.2-0.20.30.30.5-0.00.0-0.0-0.0-0.0-0.2-0.6-0.70.3
Bouts of movement, locomotor time 20.10.50.8-0.90.90.90.8-0.7-0.70.10.8-0.7-0.8-0.80.70.20.5-0.70.7-0.7-0.70.50.6-0.50.7-0.3
Total resting periods, locomotor time 20.10.20.4-0.70.70.60.5-0.5-0.5-0.10.7-0.5-0.6-0.60.5-0.00.3-0.50.5-0.5-0.40.30.4-0.30.6-0.2
Rest time, locomotor task time 20.50.91.41.1-1.1-1.1-1.01.11.0-0.6-1.20.91.11.0-0.8-0.9-0.70.9-0.90.80.8-0.8-0.81.1-1.1-0.0
Distance moved, locomotor task time 20.20.21.2-0.20.21.10.4-0.5-0.41.10.1-0.4-0.1-0.00.00.30.30.1-0.10.0-0.40.30.10.2-0.5-1.1
Vertical activity count, locomotor time 20.10.10.6-0.30.30.70.5-0.4-0.40.5-0.4-0.3-0.10.00.20.40.50.0-0.00.0-0.1-0.2-0.1-0.7-0.8-0.1
Light reinforcement 10.21.19.4-1.71.7-0.00.8-0.4-0.4-1.3-0.3-0.2-0.5-0.60.80.60.6-0.20.2-0.10.4-0.2-0.2-3.1-0.12.4
Light reinforcement 20.51.18.1-1.31.3-0.80.50.1-0.1-1.5-0.80.1-0.2-0.20.60.70.70.1-0.10.20.6-0.8-0.6-2.8-0.12.8
Bone: marrow area0.61.53.4-1.81.81.41.5-1.3-1.41.20.6-1.3-1.2-1.11.01.11.0-1.11.1-1.1-1.11.11.1-1.30.5-0.4
Bone: maximum diameter1.73.46.3-2.12.12.42.0-2.0-2.12.51.4-2.0-1.6-1.61.71.71.7-1.71.7-1.8-2.02.01.8-0.61.1-1.8
Bone: maximum force1.63.17.4-2.32.32.72.0-1.9-2.02.51.2-1.9-1.3-1.51.51.51.5-1.51.5-1.5-1.81.81.5-0.60.4-1.9
Bone: maximum moment1.32.46.4-2.02.02.51.7-1.7-1.72.40.9-1.7-1.1-1.21.21.21.3-1.21.2-1.3-1.71.61.3-0.30.2-1.9
Mean time between licks in bursts0.53.06.80.7-0.7-0.9-1.51.61.6-0.8-2.51.72.02.1-1.9-1.9-1.92.1-2.12.11.7-1.8-2.01.0-2.6-0.2
Mean num. licks in bursts0.92.33.21.6-1.6-1.5-1.71.71.7-1.5-1.11.71.51.3-1.8-1.8-1.81.5-1.51.61.6-1.5-1.51.0-1.10.7
Cd content in liver0.30.31.0-1.01.00.50.7-0.5-0.60.7-0.2-0.6-0.5-0.40.50.50.5-0.50.5-0.5-0.50.30.4-0.7-0.2-0.1
Co content in liver0.81.02.00.7-0.7-1.2-0.91.01.0-1.3-1.41.10.80.9-0.8-0.9-0.90.9-0.91.01.2-1.1-1.1-0.3-0.91.3
Cu content in liver2.93.55.01.7-1.7-1.5-1.91.91.9-1.3-2.21.92.02.1-2.0-2.0-2.02.0-2.02.01.9-1.8-1.91.3-2.20.2
Fe content in liver2.02.43.61.1-1.1-1.5-1.41.61.6-1.9-1.71.71.51.1-1.5-1.6-1.61.7-1.71.71.9-1.7-1.9-0.2-1.91.4
K content in liver0.30.30.90.4-0.4-0.8-0.40.50.5-0.9-0.70.50.40.6-0.3-0.3-0.30.5-0.50.50.6-0.7-0.6-0.4-0.51.0
Mg content in liver0.20.30.70.8-0.8-0.8-0.50.50.5-0.7-0.50.50.30.6-0.3-0.3-0.30.3-0.30.30.4-0.7-0.30.20.10.6
Mn content in liver0.91.02.8-0.80.81.51.0-1.1-1.11.70.7-1.1-0.7-0.60.80.80.8-0.90.9-0.9-1.21.01.00.30.5-1.5
Na content in liver4.24.79.01.6-1.6-1.5-2.12.22.2-1.3-3.02.22.42.2-2.5-2.5-2.52.4-2.42.42.2-2.1-2.41.3-3.00.2
Rb content in liver6.17.19.93.1-3.1-2.9-2.82.92.8-2.5-3.12.82.72.8-2.6-2.6-2.62.6-2.62.62.7-2.9-2.71.5-2.31.4
Se content in liver1.61.94.6-2.02.02.11.4-1.5-1.41.81.2-1.4-1.0-1.21.01.01.0-1.11.1-1.1-1.41.41.2-0.30.3-1.6
Sr content in liver0.50.41.6-1.31.31.00.7-0.7-0.60.40.7-0.6-0.6-0.50.50.50.5-0.60.6-0.5-0.40.40.5-0.70.3-0.3
Zn content in liver0.10.10.5-0.10.10.3-0.10.10.10.4-0.60.10.40.4-0.3-0.3-0.30.4-0.40.40.1-0.1-0.20.5-0.7-0.7
Bone: minimum diameter0.00.10.40.2-0.20.1-0.10.00.00.4-0.00.00.10.1-0.3-0.2-0.30.1-0.10.1-0.10.20.10.6-0.1-0.7
Time in familiar zone, hab. session 10.50.64.60.8-0.80.2-0.3-0.1-0.01.20.5-0.20.00.1-0.1-0.1-0.1-0.30.3-0.4-0.60.70.62.10.5-1.8
Time in novel zone, hab. session 13.94.37.80.9-0.9-1.8-1.72.02.0-2.8-2.52.22.01.8-1.9-1.9-1.82.3-2.32.42.6-2.6-2.5-1.0-2.42.4
Total zone transitions, hab. session 10.00.00.3-0.10.10.2-0.10.10.10.1-0.30.10.30.3-0.1-0.3-0.20.3-0.30.30.20.0-0.30.1-0.5-0.2
Total locomotion distance, hab. session 10.30.43.0-0.60.61.10.4-0.5-0.51.40.1-0.5-0.10.00.20.10.2-0.20.2-0.3-0.60.60.40.9-0.3-1.7
Locomotion velocity, hab. session 11.11.54.1-1.51.51.91.2-1.3-1.32.00.7-1.3-0.9-0.61.00.91.0-1.01.0-1.0-1.41.31.10.20.3-1.9
Time in familiar zone, hab. session 20.60.73.31.1-1.1-0.1-0.90.70.70.2-0.60.60.91.1-0.9-0.9-0.80.7-0.70.60.4-0.5-0.51.8-0.8-1.1
Time in novel zone, hab. session 21.31.44.60.9-0.9-1.8-1.01.21.1-2.0-1.01.20.80.7-0.8-0.8-0.91.0-1.11.11.4-1.2-1.2-0.9-0.52.1
Total zone transitions, hab. session 20.30.41.3-1.01.00.60.7-0.6-0.60.10.3-0.5-0.6-0.40.60.60.6-0.50.5-0.4-0.40.50.3-1.20.10.4
Total locomotion distance, hab. session 20.60.71.4-1.21.21.11.0-0.9-0.90.90.6-0.9-0.8-0.60.80.70.8-0.80.8-0.8-0.91.00.8-0.50.2-0.6
Locomotion velocity, hab. session 20.81.11.8-1.41.41.41.2-1.1-1.21.20.8-1.2-1.0-0.71.00.91.0-1.01.0-1.0-1.11.21.0-0.50.4-0.8
Novel to familiar place preference ratio2.63.46.91.9-1.9-2.3-1.82.01.9-2.6-1.82.01.61.5-1.6-1.5-1.61.8-1.81.82.1-2.1-1.9-0.1-1.22.2
Novelty place preference3.44.37.92.2-2.2-2.6-2.12.22.2-2.8-2.02.21.91.8-1.8-1.8-1.92.0-2.02.12.3-2.3-2.10.2-1.42.2
Time in novel zone, NPP test4.75.79.82.5-2.5-2.9-2.42.62.5-3.1-2.42.62.22.1-2.2-2.1-2.22.4-2.42.42.7-2.7-2.50.3-1.72.4
Total zone transitions, NPP test0.30.42.0-1.21.20.70.8-0.6-0.6-0.10.3-0.5-0.5-0.50.50.50.5-0.40.4-0.4-0.20.50.2-1.4-0.10.5
Total locomotion distance, NPP test1.82.54.0-2.02.01.31.8-1.6-1.70.81.5-1.6-1.7-1.61.71.61.7-1.61.6-1.6-1.41.51.5-1.91.10.2
Locomotion velocity, NPP test2.63.75.0-2.22.21.72.1-2.0-2.01.21.9-2.0-2.1-2.02.12.02.0-2.02.0-2.0-1.82.01.9-1.81.6-0.1
Intraocular pressure2.94.77.0-2.12.11.52.3-2.2-2.31.62.2-2.2-2.4-2.32.42.52.6-2.32.3-2.3-2.12.12.2-2.02.60.1
Delta distance traveled before/after self-admin0.50.51.2-0.20.2-0.2-0.70.70.6-0.0-1.00.61.10.8-0.7-0.7-0.60.8-0.80.80.5-0.5-0.81.1-1.1-0.7
Delta ambulatory time before/after self-admin1.01.73.10.3-0.3-0.7-1.31.31.3-0.4-1.61.21.81.6-1.4-1.4-1.31.5-1.51.51.1-1.2-1.51.5-1.8-0.6
Parametrial fat weight0.40.92.00.6-0.6-0.7-0.70.80.8-1.3-1.20.90.70.7-0.9-1.0-0.90.9-0.91.01.1-1.1-1.0-0.5-1.41.0
Pavlov. Cond. lever latency5.77.211.13.3-3.3-3.0-3.02.93.0-2.4-2.42.92.62.5-2.8-2.7-2.72.7-2.72.72.7-2.7-2.62.1-1.91.0
Pavlov. Cond. magazine entry latency0.20.31.2-1.01.01.10.6-0.6-0.50.80.3-0.5-0.3-0.20.20.20.1-0.30.3-0.3-0.40.50.4-0.2-0.2-0.7
Pavlov. Cond. change in total contacts2.32.53.7-1.91.91.71.8-1.7-1.71.31.5-1.7-1.6-1.51.61.61.5-1.61.6-1.6-1.61.61.5-1.31.1-0.5
Pavlov. Cond. index score2.12.75.3-2.32.32.31.9-1.8-1.81.81.3-1.8-1.4-1.31.51.41.4-1.51.5-1.5-1.71.61.5-1.00.7-1.2
Pavlov. Cond. latency score2.12.74.8-2.22.22.21.9-1.8-1.81.81.4-1.8-1.5-1.41.61.51.5-1.61.6-1.6-1.71.61.5-1.00.8-1.1
Pavlov. Cond. lever contacts5.56.79.5-3.13.12.92.9-2.8-2.92.42.4-2.8-2.5-2.32.72.62.6-2.62.6-2.6-2.72.62.5-1.81.9-1.1
Pavlov. Cond. magazine entry number0.50.61.51.0-1.0-1.2-0.80.80.8-1.1-0.70.80.60.5-0.6-0.5-0.50.7-0.70.70.8-0.9-0.70.1-0.20.9
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.60.60.50.4-0.4-0.40.60.2-0.4-0.2-0.40.40.30.4-0.20.2-0.2-0.40.40.2-0.2-0.0-0.4
Pavlov. Cond. lever-magazine prob. diff.2.22.75.6-2.22.22.41.8-1.8-1.82.01.3-1.8-1.4-1.31.51.31.4-1.51.5-1.5-1.71.71.5-0.70.7-1.5
Pavlov. Cond. response bias2.73.46.3-2.52.52.42.1-2.0-2.11.91.6-2.0-1.7-1.61.81.71.7-1.71.7-1.7-1.91.91.7-1.31.0-1.1
Pavlov. Cond. lever latency1.62.35.51.7-1.7-2.3-1.61.71.6-2.2-1.31.61.21.3-1.1-1.1-1.11.3-1.31.31.7-1.6-1.5-0.0-0.52.1
Pavlov. Cond. magazine entry latency0.91.22.60.8-0.8-0.2-1.11.01.0-0.3-1.31.01.21.3-1.4-1.4-1.41.3-1.31.31.0-1.0-1.11.1-1.6-0.6
Pavlov. Cond. change in total contacts0.30.86.1-0.50.51.70.4-0.6-0.51.80.1-0.60.00.1-0.0-0.1-0.1-0.10.1-0.2-0.70.60.41.3-0.8-2.5
Pavlov. Cond. index score0.20.43.1-0.10.11.1-0.0-0.1-0.11.1-0.3-0.10.30.3-0.5-0.5-0.50.3-0.30.2-0.20.1-0.01.1-0.9-1.8
Pavlov. Cond. latency score0.30.43.5-0.20.21.20.2-0.4-0.31.30.1-0.30.00.1-0.2-0.3-0.30.0-0.0-0.0-0.50.50.31.1-0.5-1.9
Pavlov. Cond. lever contacts1.01.54.3-1.41.42.11.2-1.4-1.32.00.9-1.3-0.9-1.00.70.70.7-0.90.9-0.9-1.31.21.10.20.1-2.0
Pavlov. Cond. magazine entry number0.40.53.3-0.20.2-0.80.3-0.1-0.2-1.00.4-0.1-0.5-0.50.70.70.7-0.40.4-0.40.1-0.00.2-1.50.91.8
Pavlov. Cond. intertrial magazine entries0.51.12.0-0.70.70.41.0-1.0-1.00.61.0-1.1-1.2-1.21.31.31.3-1.21.2-1.2-1.10.91.1-0.71.40.1
Pavlov. Cond. lever-magazine prob. diff.0.30.43.6-0.10.11.1-0.1-0.1-0.01.2-0.3-0.10.40.4-0.5-0.5-0.50.3-0.30.3-0.20.2-0.01.3-1.0-1.9
Pavlov. Cond. response bias0.40.63.6-0.70.71.60.5-0.6-0.61.50.2-0.6-0.2-0.2-0.0-0.0-0.0-0.20.2-0.2-0.60.50.40.7-0.6-1.9
Time in closed arm before self-admin0.10.20.80.8-0.8-0.7-0.30.20.2-0.60.20.1-0.1-0.1-0.60.00.10.1-0.10.10.00.10.10.40.90.3
Time in closed arm after self-admin0.40.42.01.1-1.1-0.2-0.50.40.30.5-0.60.20.50.7-0.9-0.6-0.70.4-0.40.4-0.0-0.1-0.11.4-0.6-1.0
Time in open arm before self-admin0.60.72.2-1.51.50.71.0-0.8-0.80.60.3-0.8-0.7-0.71.20.90.8-0.70.7-0.6-0.60.40.5-1.40.10.4
Time in open arm after self-admin1.41.63.3-1.61.60.91.2-1.2-1.10.21.6-1.0-1.4-1.51.61.41.3-1.21.2-1.2-0.80.91.0-1.81.40.8
Bone: periosteal estimation0.92.24.0-1.91.92.01.7-1.7-1.72.01.0-1.6-1.4-1.31.21.31.2-1.41.4-1.4-1.61.61.5-0.70.6-1.3
Bone: periosteal perimeter0.40.71.2-1.11.10.81.0-0.9-0.90.60.7-0.9-0.9-0.90.70.80.7-0.90.9-0.8-0.80.90.8-0.90.7-0.1
Bone: post-yield work1.11.84.8-2.22.21.61.7-1.5-1.51.00.8-1.4-1.2-1.21.31.41.4-1.11.1-1.1-1.11.11.0-1.80.5-0.1
Progressive ratio test 1 active lever presses0.50.94.60.4-0.4-1.00.2-0.2-0.1-1.01.6-0.2-0.9-0.90.80.80.8-0.70.7-0.6-0.10.30.5-1.31.92.2
Progressive ratio test 1 breakpoint0.50.94.00.3-0.3-0.90.2-0.3-0.2-0.81.6-0.2-1.0-0.90.80.90.8-0.80.8-0.7-0.20.40.6-1.31.92.0
Progressive ratio test 1 inactive lever presses0.61.64.6-1.31.30.21.2-1.1-1.0-0.11.5-1.0-1.5-1.61.41.41.4-1.21.2-1.1-0.70.81.0-2.21.71.5
Progressive ratio test 2 active lever presses0.40.65.10.4-0.4-1.3-0.20.20.2-1.31.00.2-0.4-0.30.50.60.6-0.20.2-0.10.4-0.2-0.0-1.31.22.3
Progressive ratio test 2 breakpoint0.50.65.30.5-0.5-1.3-0.20.20.3-1.40.90.3-0.3-0.20.40.60.5-0.10.1-0.10.4-0.2-0.1-1.31.12.3
Progressive ratio test 2 inactive lever presses0.30.92.5-0.60.60.20.7-0.7-0.70.41.6-0.8-1.0-1.11.01.21.3-1.01.0-0.9-0.71.00.9-0.91.40.6
Incentive Sensitization - Responses0.10.31.80.4-0.4-1.0-0.40.50.5-1.0-0.10.50.20.3-0.10.20.10.3-0.30.40.6-0.5-0.5-0.60.01.4
Incentive Sensitization - Breakpoint0.10.31.90.5-0.5-1.0-0.40.50.5-1.1-0.10.50.20.3-0.10.20.10.3-0.30.30.6-0.5-0.4-0.60.11.4
Sum of active levers in priming session hrs 5-61.91.85.20.9-0.9-2.0-1.41.61.5-2.3-0.71.51.11.1-0.5-1.0-1.01.1-1.11.11.6-1.5-1.5-0.4-0.12.3
Progressive ratio0.00.00.3-0.30.30.1-0.0-0.10.0-0.00.20.1-0.10.1-0.1-0.0-0.00.1-0.10.10.1-0.1-0.0-0.20.60.1
Food seeking constrained by brief footshock8.811.115.0-3.43.42.43.6-3.5-3.41.53.5-3.3-3.8-3.73.73.93.9-3.53.5-3.4-3.03.03.2-3.53.90.6
Seeking ratio, punishment vs. effort1.32.83.9-1.61.61.31.8-1.7-1.81.01.6-1.8-1.9-1.92.01.91.9-1.91.9-1.8-1.71.61.7-1.51.4-0.0
Retroperitoneal fat weight0.52.33.61.6-1.6-0.9-1.61.51.5-0.8-1.91.51.71.7-1.7-1.8-1.81.7-1.71.61.4-1.3-1.51.5-1.7-0.3
Reaction time number correct0.10.30.7-0.50.50.30.6-0.5-0.5-0.30.8-0.5-0.5-0.50.80.70.8-0.50.5-0.5-0.40.60.4-0.90.40.6
Reaction time mean minus median0.10.97.5-0.50.51.50.2-0.4-0.42.30.2-0.50.20.2-0.0-0.0-0.1-0.00.1-0.2-0.80.50.41.90.3-2.7
Reaction time mean minus median AUC0.21.15.8-1.01.01.80.7-0.9-0.92.40.6-0.9-0.3-0.30.60.50.5-0.50.5-0.6-1.10.90.71.10.7-2.4
Reaction time num false alarms0.10.10.9-0.10.10.6-0.0-0.1-0.00.70.1-0.10.2-0.1-0.1-0.2-0.2-0.00.0-0.0-0.10.2-0.00.6-0.1-1.0
Reaction time num false alarms AUC0.20.51.0-0.70.71.00.6-0.7-0.71.00.9-0.7-0.5-0.80.60.40.5-0.70.7-0.7-0.60.80.6-0.20.8-0.6
Reaction time trials correct on left0.10.30.7-0.50.50.30.6-0.5-0.5-0.30.8-0.5-0.5-0.50.80.70.8-0.50.5-0.5-0.40.60.4-0.90.40.6
Reaction time trials on left0.10.20.6-0.40.40.20.5-0.4-0.4-0.40.7-0.4-0.4-0.40.70.60.7-0.40.4-0.4-0.30.50.3-0.80.30.6
Reaction time mean1.43.17.41.6-1.6-0.8-1.81.71.70.5-2.01.62.12.2-2.0-1.9-1.92.0-2.01.91.3-1.5-1.62.7-1.5-1.6
Reaction time mean AUC1.43.37.91.7-1.7-0.8-1.91.81.70.5-1.91.72.22.2-2.0-2.0-2.02.0-2.01.91.4-1.5-1.72.8-1.6-1.6
Median of all reaction times3.55.47.62.3-2.3-1.8-2.52.42.4-0.6-2.72.42.72.8-2.5-2.5-2.42.6-2.62.52.1-2.3-2.32.5-2.1-0.6
Reaction time omissions1.82.94.01.4-1.4-1.6-1.91.91.9-1.0-1.71.91.91.9-1.8-1.8-1.82.0-2.02.01.9-1.9-1.91.0-1.10.5
Reaction time false alarm rate0.10.10.60.2-0.20.3-0.20.10.20.7-0.00.10.30.0-0.3-0.4-0.40.1-0.10.10.1-0.0-0.10.70.2-0.8
Reaction time premature initiation rate0.91.54.42.1-2.1-1.6-1.61.41.3-0.6-0.61.21.10.9-1.3-1.1-1.10.9-0.90.80.9-0.9-0.81.9-0.0-0.1
Reaction time premature initiations0.20.72.71.7-1.7-1.3-1.11.00.9-0.8-0.10.80.70.5-0.7-0.5-0.60.5-0.50.40.6-0.5-0.51.20.30.3
Std. dev. reaction times0.31.25.00.3-0.30.5-0.80.60.61.5-1.00.61.21.2-1.1-1.2-1.21.0-1.00.90.3-0.6-0.72.2-0.8-2.2
Reaction time trials completed0.10.20.6-0.40.40.20.5-0.4-0.4-0.40.7-0.4-0.4-0.40.70.60.7-0.40.4-0.4-0.30.50.3-0.80.30.6
Reaction time trials AUC0.10.20.6-0.40.40.20.5-0.4-0.4-0.40.6-0.4-0.4-0.40.70.60.7-0.40.4-0.4-0.40.50.3-0.80.30.6
Run reversals in cocaine runway, females0.20.21.0-0.80.80.1-0.10.10.01.0-0.5-0.00.30.5-0.5-0.1-0.10.2-0.20.2-0.20.0-0.00.90.1-1.0
Run reversals in cocaine runway, males0.00.00.20.4-0.4-0.1-0.1-0.00.1-0.20.10.00.00.00.2-0.0-0.10.0-0.0-0.00.00.0-0.00.10.10.1
Latency to leave start box in cocaine runway0.50.71.1-0.50.50.80.9-0.9-1.00.80.7-1.0-0.7-0.71.10.80.8-0.90.9-1.0-1.01.00.9-0.20.7-0.6
Latency to leave start box in cocaine runway, F0.10.10.40.6-0.6-0.4-0.10.10.1-0.60.20.10.10.10.30.10.10.1-0.10.10.1-0.1-0.1-0.30.10.6
Latency to leave start box in cocaine runway, M1.61.52.0-1.41.41.11.4-1.4-1.41.20.8-1.4-1.4-1.31.31.01.1-1.41.4-1.4-1.41.21.3-0.81.0-0.6
Std. dev. time between licks in bursts0.40.71.00.6-0.6-0.7-0.80.80.9-0.5-1.00.90.91.0-0.9-0.9-0.91.0-1.01.00.9-0.6-0.90.6-1.00.0
Total sessions with >9 infusions0.50.62.9-0.20.2-0.50.4-0.3-0.3-0.81.2-0.3-0.7-0.80.80.80.7-0.60.6-0.5-0.10.30.4-1.41.21.7
Short access day 1 total inactive lever presses0.81.63.3-1.11.1-0.11.1-1.0-1.0-0.01.6-1.0-1.5-1.61.61.51.5-1.41.4-1.4-0.91.11.2-1.61.81.3
Short access day 10 total inactive lever presses0.10.71.0-1.01.00.70.9-0.9-0.90.80.7-0.9-1.0-0.90.90.60.5-1.01.0-1.0-0.90.81.0-0.30.6-0.6
Short access day 1 total infusions0.40.83.6-0.40.4-0.70.5-0.4-0.4-0.71.3-0.3-0.9-1.01.10.90.9-0.70.7-0.7-0.10.40.4-1.71.31.9
Short access day 10 total infusions0.30.63.7-0.20.2-0.90.2-0.1-0.1-0.90.8-0.1-0.6-0.60.80.80.7-0.50.5-0.40.00.10.2-1.41.21.9
Short access total infusions0.40.65.00.2-0.2-1.10.10.00.0-1.21.00.0-0.6-0.60.70.70.6-0.40.4-0.30.2-0.00.1-1.51.12.2
Short access day 1 locomotion0.40.72.51.0-1.0-1.4-0.90.90.9-1.50.50.80.50.5-0.5-0.6-0.60.6-0.60.60.9-0.6-0.7-0.20.71.6
Short access day 10 total locomotion0.10.61.61.3-1.3-0.7-0.90.80.8-0.70.00.70.80.6-0.9-0.9-1.00.7-0.70.70.6-0.3-0.51.00.1-0.1
Short access total locomotion0.20.31.50.2-0.2-1.0-0.30.40.4-1.00.60.30.0-0.2-0.2-0.1-0.20.2-0.20.20.4-0.1-0.2-0.51.01.2
One hour access (0.3 mA shock)0.70.91.8-0.40.40.20.9-0.8-0.8-0.01.1-0.8-1.2-1.11.21.11.0-1.11.1-1.1-0.70.70.9-1.31.01.0
Compulsive drug intake0.20.31.80.2-0.21.30.3-0.5-0.40.8-0.1-0.4-0.00.10.1-0.1-0.1-0.20.2-0.3-0.40.20.30.6-0.6-1.3
One hour access (shock baseline)0.41.24.2-0.30.3-0.60.7-0.7-0.6-0.71.4-0.6-1.3-1.31.11.31.3-1.01.0-0.9-0.40.60.8-1.91.62.0
Social response proportion4.05.19.01.7-1.7-1.3-2.32.22.3-0.8-3.02.32.62.5-2.5-2.6-2.62.5-2.52.52.1-2.1-2.32.1-2.9-0.5
Social responses0.20.31.1-1.11.11.00.6-0.6-0.60.90.0-0.5-0.4-0.30.30.30.2-0.30.3-0.3-0.50.60.3-0.2-0.2-0.8
Social time1.52.46.9-0.10.1-0.5-1.21.31.3-0.6-2.51.51.81.9-1.6-1.6-1.61.9-1.91.91.6-1.7-1.90.5-2.6-0.1
Soleus weight0.51.35.7-0.50.5-0.8-0.30.80.7-1.8-1.21.00.70.3-0.5-0.6-0.71.0-1.01.11.4-1.3-1.4-2.2-1.22.4
Bone: stiffness1.42.68.2-2.62.62.91.8-1.7-1.82.40.5-1.7-1.0-1.21.01.11.1-1.01.0-1.1-1.51.41.1-0.7-0.4-2.0
Tibialis anterior weight6.321.630.8-5.55.54.65.3-5.1-5.13.94.1-4.9-4.8-5.04.94.84.9-4.84.8-4.7-4.54.44.5-4.23.5-1.0
Time to tail flick, vehicle, before self-admin0.20.22.21.5-1.5-0.3-0.30.20.2-0.10.20.1-0.10.2-0.4-0.2-0.10.0-0.00.0-0.00.20.20.60.3-0.1
Time to tail flick, vehicle, after self-admin0.10.31.21.1-1.10.30.3-0.4-0.40.30.7-0.4-0.5-0.70.30.50.4-0.30.3-0.3-0.50.70.50.0-0.0-0.3
Time to tail flick, test, before self-admin0.50.61.3-0.90.90.60.8-1.0-0.80.70.5-0.8-1.0-0.80.60.70.6-0.90.9-0.8-0.80.81.0-0.41.2-0.3
Time to tail flick, test, after self-admin3.23.45.8-1.41.42.01.7-2.0-1.92.42.0-2.0-1.8-1.81.61.41.3-2.02.0-2.0-2.22.22.10.31.8-2.0
Delta time to tail flick, vehicle, before/after SA0.10.10.5-0.40.40.40.1-0.0-0.00.3-0.30.00.3-0.1-0.2-0.1-0.20.3-0.30.30.1-0.1-0.3-0.1-0.7-0.3
Delta time to tail flick, test, before/after SA0.10.21.00.4-0.40.50.0-0.1-0.20.60.7-0.30.0-0.20.00.00.0-0.20.2-0.3-0.40.50.30.90.1-1.0
Tibia length0.51.44.70.1-0.1-0.7-0.61.00.9-1.3-2.01.11.11.0-1.0-1.0-1.01.2-1.21.31.4-1.5-1.5-1.0-2.21.3
Ambulatory time before self-admin0.82.34.3-1.31.31.41.8-1.6-1.70.81.5-1.6-1.7-1.72.01.81.8-1.61.6-1.6-1.31.31.4-2.10.80.4
Ambulatory time after self-admin0.10.20.6-0.60.60.70.4-0.2-0.30.30.1-0.30.2-0.30.60.30.4-0.10.1-0.1-0.20.3-0.1-0.4-0.8-0.2
Bone: tissue strength0.60.62.6-0.20.20.6-0.40.40.40.3-1.30.50.91.0-0.8-0.8-0.80.8-0.80.80.5-0.9-0.80.4-1.6-0.8
Total heroin consumption1.01.15.80.8-0.8-1.5-0.91.01.1-2.0-0.21.10.60.6-0.3-0.7-0.70.8-0.80.81.3-1.1-1.1-1.00.02.4
Bone: trabecular number1.01.93.4-1.41.41.81.3-1.4-1.41.91.5-1.5-1.1-1.21.21.41.4-1.31.3-1.3-1.51.61.3-0.11.1-1.4
Bone: trabecular spacing0.00.00.30.1-0.1-0.1-0.10.10.10.4-0.20.00.10.2-0.2-0.3-0.30.1-0.10.0-0.10.00.10.6-0.1-0.5
Bone: trabecular thickness0.00.10.30.3-0.30.1-0.30.20.20.10.20.20.30.2-0.1-0.2-0.10.2-0.20.20.1-0.1-0.20.5-0.1-0.4
Bone: trabecular tissue density0.81.34.9-2.22.22.01.4-1.3-1.31.40.2-1.1-0.8-0.90.70.60.6-0.70.7-0.7-0.90.90.7-1.1-0.6-1.0
Water consumed over 24 hours0.81.52.4-0.80.81.31.2-1.2-1.31.31.5-1.3-1.4-1.31.21.21.2-1.41.4-1.4-1.41.21.5-0.31.5-0.6
Number of responses in last shaping day0.70.97.70.2-0.2-1.4-0.20.50.4-2.1-0.50.5-0.00.10.30.20.20.2-0.20.30.8-0.9-0.6-2.00.12.8