Hub : Genes

Reck

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Reck 0.03 0.02 1.4e-04 0.03 0.03 0.03 0.03 1.4e-04 2.1e-04 3.3e-04 3.7e-04
2 Adipose gene expression Reck 0.11 0.06 5.4e-12 0.07 0.07 0.07 0.06 7.2e-08 7.6e-08 7.7e-08 1.2e-07
3 RMTg mRNA stability Reck 0.09 0.06 7.4e-03 0.06 0.07 0.1 0.07 8.7e-03 5.3e-03 1.5e-03 6.2e-03
4 Adipose alternative TSS NM_001415923.1 0.02 0.02 3.8e-03 0.02 0.02 0.02 0.02 1.6e-03 2.7e-03 3.4e-03 4.2e-03
5 Adipose alternative TSS XM_006238069.3 0.02 0.02 4.2e-03 0.02 0.02 0.02 0.02 1.7e-03 2.9e-03 3.4e-03 3.9e-03
6 NAcc alternative TSS NM_001415923.1 0.02 0.02 7.5e-04 0.02 0.02 0.02 0.02 5.2e-03 2.0e-03 2.8e-03 4.0e-03
7 NAcc alternative TSS XM_006238069.3 0.02 0.02 7.7e-04 0.02 0.02 0.02 0.02 5.0e-03 2.0e-03 2.9e-03 4.2e-03
8 Brain mRNA stability Reck 0.08 0.05 2.4e-06 0.07 0.06 0.06 0.06 1.0e-06 2.8e-06 2.4e-06 1.7e-06
9 RMTg gene expression Reck 0.16 0.1 2.7e-04 0.18 0.16 0.12 0.17 1.1e-05 4.5e-05 4.5e-04 2.9e-05
10 PL gene expression Reck 0.31 0.11 0.0e+00 0.4 0.43 0.43 0.43 7.5e-47 5.8e-52 7.7e-52 9.1e-52
11 PL alternative TSS XM_006238069.3 0.03 0.02 5.5e-05 0.03 0.03 0.03 0.03 4.6e-04 1.3e-04 2.2e-04 2.3e-04
12 PL alternative TSS NM_001415923.1 0.03 0.02 6.5e-05 0.03 0.03 0.03 0.03 2.0e-04 1.4e-04 2.2e-04 2.5e-04
13 BLA gene expression Reck 0.34 0.15 4.5e-13 0.22 0.21 0.21 0.21 7.5e-12 2.4e-11 1.1e-11 1.5e-11
14 NAcc gene expression Reck 0.21 0.07 0.0e+00 0.32 0.32 0.33 0.33 5.1e-38 1.6e-38 6.8e-39 6.7e-39
15 OFC gene expression Reck 0.56 0.16 1.6e-11 0.34 0.36 0.37 0.38 5.1e-09 2.1e-09 7.9e-10 6.8e-10
16 IL gene expression Reck 0.53 0.17 9.0e-14 0.45 0.51 0.51 0.52 2.9e-12 4.2e-14 3.2e-14 2.0e-14
17 PL mRNA stability Reck 0.04 0.03 5.2e-03 0.01 0.02 0.02 0.02 6.3e-02 1.4e-03 1.3e-03 2.4e-03
18 Brain gene expression Reck 0.34 0.13 0.0e+00 0.4 0.42 0.42 0.42 5.9e-39 3.8e-42 7.6e-42 8.6e-42
19 LHb gene expression Reck 0.33 0.19 3.1e-04 0.14 0.14 0.16 0.14 3.8e-04 3.1e-04 9.9e-05 2.8e-04
20 NAcc intron excision ratio chr5_58123036_58124285 0.03 0.03 2.4e-03 0.02 0.02 0.02 0.02 7.1e-04 1.4e-03 2.9e-03 1.2e-03
21 IL mRNA stability Reck 0.11 0.09 9.7e-03 0.03 0.01 0.05 0.04 5.2e-02 1.8e-01 2.9e-02 3.8e-02
22 Liver gene expression Reck 0.18 0.09 1.5e-14 0.06 0.12 0.11 0.12 1.0e-07 2.0e-13 1.6e-12 6.4e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.52.53.31.3-1.31.61.7-1.7-1.71.71.61.8-1.71.7-1.71.7-1.8-1.8-1.80.6-1.81.81.61.1-1.0
Area under the delay curve0.40.50.9-0.50.5-0.6-0.40.40.7-0.7-0.5-0.60.7-0.80.8-0.80.70.60.70.20.9-0.8-0.5-0.81.0
BMI with tail3.09.812.62.7-2.73.13.2-3.2-3.33.33.23.3-3.43.4-3.43.2-3.4-3.4-3.51.3-3.53.43.42.7-2.0
BMI without tail5.210.714.83.8-3.83.73.2-3.2-3.63.63.23.4-3.53.6-3.63.3-3.2-3.2-3.12.7-3.32.53.52.7-1.3
Body weight3.715.618.64.1-4.04.14.3-4.3-4.34.34.24.1-4.34.3-4.34.0-4.2-4.2-4.23.1-4.13.73.72.6-1.4
Weight adjusted by age0.60.62.30.7-0.60.31.0-1.0-0.70.61.00.9-0.60.5-0.51.2-0.8-0.7-0.51.5-0.40.6-0.1-0.41.2
Bone surface0.81.41.91.1-1.11.21.4-1.4-1.31.31.31.2-1.31.3-1.21.3-1.3-1.4-1.31.1-1.21.31.10.5-0.1
Bone volume0.81.42.01.0-1.01.11.3-1.3-1.31.31.31.3-1.21.3-1.31.3-1.3-1.4-1.30.7-1.31.41.10.6-0.4
Breakpoint value in progressive ratio session0.40.53.9-0.10.1-0.40.2-0.20.2-0.20.10.20.2-0.40.40.20.00.00.31.30.6-0.2-0.9-1.52.0
Number of licking bursts3.94.66.02.3-2.32.52.1-2.1-2.32.42.12.1-2.32.4-2.42.1-2.2-2.1-2.21.1-2.41.82.11.7-1.5
Context. condit. distance diff. score0.00.00.2-0.40.4-0.30.1-0.10.1-0.1-0.00.20.0-0.10.10.1-0.1-0.2-0.2-0.4-0.10.5-0.1-0.3-0.1
Locomotion velocity, session 11.21.38.61.3-1.30.31.0-1.0-0.80.81.11.1-0.60.5-0.41.1-0.7-0.6-0.22.90.00.5-0.2-1.22.6
Locomotion distance, session 10.30.42.60.9-1.00.50.6-0.6-0.50.50.50.5-0.40.3-0.30.5-0.3-0.3-0.11.60.0-0.10.1-0.31.3
Locomotion velocity, session 22.42.84.81.9-1.92.01.4-1.4-1.71.71.51.5-1.81.8-1.81.5-1.5-1.5-1.60.7-1.71.22.12.2-1.5
Locomotion distance, session 20.81.23.92.0-2.01.60.8-0.8-1.21.20.80.7-1.01.1-1.10.8-0.6-0.6-0.41.8-0.5-0.30.80.90.2
Locomotion velocity, session 30.20.21.70.4-0.4-0.10.2-0.2-0.20.10.20.3-0.10.00.00.30.0-0.00.21.20.2-0.1-0.3-0.71.3
Locomotion distance, session 33.53.85.31.7-1.71.62.3-2.3-2.12.02.32.3-2.01.9-1.92.2-2.2-2.2-2.02.0-1.92.11.60.60.3
Stereotopy head waving bouts, day 30.60.72.50.00.0-0.6-0.50.50.5-0.5-0.4-0.30.6-0.70.7-0.50.60.81.01.01.0-1.0-1.4-1.51.6
Stereotopy head waving duration, day 30.70.82.0-0.40.4-0.8-0.80.80.8-0.8-0.7-0.70.9-0.90.9-0.70.91.01.10.31.0-1.1-1.4-1.41.1
Locomotion velocity, session 70.00.00.1-0.30.3-0.3-0.10.10.2-0.2-0.2-0.20.2-0.20.2-0.10.20.20.1-0.20.2-0.1-0.1-0.10.1
Locomotion distance, session 70.30.30.50.6-0.70.50.7-0.7-0.60.60.60.6-0.60.6-0.60.7-0.6-0.7-0.60.6-0.50.60.50.10.1
Stereotopy head waving bouts, day 72.93.24.71.8-1.71.72.0-2.0-2.01.92.12.2-1.91.9-1.92.1-2.0-1.8-1.81.9-1.81.61.40.60.0
Stereotopy head waving duration, day 70.40.51.21.0-1.00.70.6-0.6-0.80.80.70.8-0.70.7-0.70.7-0.6-0.4-0.41.1-0.50.20.30.10.3
Locomotion velocity, session 80.40.51.80.4-0.3-0.2-0.70.70.4-0.4-0.8-0.60.6-0.50.5-0.60.90.81.00.71.0-1.3-0.7-0.40.9
Locomotion distance, session 80.10.21.10.7-0.80.40.2-0.2-0.30.30.10.3-0.20.2-0.20.2-0.0-0.10.11.10.1-0.3-0.2-0.30.7
Degree of sensitization distance2.12.13.2-1.11.0-1.1-1.71.71.5-1.5-1.8-1.81.6-1.51.5-1.71.71.61.6-1.31.5-1.7-1.3-0.5-0.1
Degree of sensitization stereotypy2.12.33.41.3-1.31.31.7-1.7-1.61.61.81.8-1.71.6-1.61.8-1.8-1.6-1.61.3-1.61.61.40.7-0.1
Conditioned locomotion0.30.32.1-0.00.1-0.20.6-0.6-0.30.20.60.7-0.30.1-0.10.7-0.5-0.4-0.21.3-0.10.5-0.1-0.91.5
Cocaine response after cond. corrected1.61.84.7-1.21.3-1.7-1.01.01.3-1.3-1.0-0.91.3-1.41.5-0.91.21.21.40.31.5-0.9-1.8-2.12.2
Cocaine response after cond. not corrected2.02.24.8-1.01.0-1.6-1.31.31.3-1.4-1.3-1.21.5-1.51.6-1.21.51.51.70.51.8-1.5-2.0-2.02.2
Cocaine response before conditioning0.30.31.11.0-1.11.00.3-0.3-0.60.60.30.2-0.50.6-0.60.2-0.3-0.3-0.30.3-0.4-0.10.40.7-0.7
Saline control response0.60.72.81.1-1.00.61.0-1.0-0.90.91.01.0-0.80.8-0.80.9-0.8-0.6-0.51.7-0.50.50.0-0.60.9
Bone: connectivity density1.01.62.30.8-0.91.21.3-1.3-1.31.31.31.4-1.41.3-1.31.3-1.4-1.4-1.50.2-1.51.51.51.2-0.9
Bone: cortical apparent density0.20.32.4-0.60.5-0.1-0.40.40.3-0.3-0.4-0.30.2-0.10.1-0.40.10.1-0.1-1.5-0.20.10.40.9-1.4
Bone: cortical area1.72.63.81.6-1.61.91.5-1.5-1.71.71.51.3-1.71.8-1.81.4-1.6-1.7-1.70.5-1.81.32.01.9-1.7
Bone: cortical porosity0.30.40.6-0.70.7-0.8-0.60.60.6-0.6-0.6-0.50.6-0.60.6-0.50.60.70.6-0.40.6-0.5-0.7-0.60.3
Bone: cortical porosity0.00.10.10.00.0-0.00.3-0.3-0.20.20.30.3-0.20.2-0.20.3-0.2-0.2-0.20.2-0.20.4-0.0-0.30.1
Bone: cortical thickness1.01.62.90.7-0.61.21.2-1.2-1.11.11.11.0-1.21.3-1.31.1-1.3-1.4-1.5-0.3-1.51.51.71.6-1.7
Bone: cortical thickness0.20.20.5-0.70.7-0.5-0.50.50.5-0.5-0.5-0.60.5-0.40.4-0.60.50.40.4-0.70.4-0.30.00.3-0.4
Bone: cortical tissue density0.20.32.3-0.60.6-0.2-0.40.40.4-0.4-0.4-0.30.3-0.20.2-0.50.20.1-0.0-1.5-0.10.00.30.7-1.3
Condit. Reinf. active minus inactive responses0.30.41.00.7-0.70.80.4-0.4-0.60.70.30.5-0.60.7-0.70.5-0.5-0.5-0.50.3-0.60.40.81.0-0.7
Condit. Reinf. active-inactive response ratio0.70.71.2-1.11.1-0.9-1.11.10.9-0.9-1.0-0.80.9-0.90.9-0.90.80.90.8-0.80.8-0.7-0.6-0.20.0
Condit. Reinf. active responses2.22.74.32.0-1.92.11.4-1.4-1.81.81.31.4-1.81.9-1.91.5-1.5-1.5-1.50.9-1.71.11.82.0-1.4
Condit. Reinf. inactive responses2.32.85.12.2-2.22.31.3-1.3-1.81.81.41.2-1.71.9-1.91.3-1.4-1.4-1.50.6-1.70.91.82.1-1.9
Incentive salience index mean3.74.56.52.5-2.52.52.0-2.0-2.42.41.92.1-2.32.4-2.42.1-2.0-2.1-2.01.7-2.11.72.22.0-1.1
Condit. Reinf. lever presses9.112.219.14.4-4.34.13.4-3.4-3.93.93.43.6-3.83.8-3.83.5-3.4-3.4-3.33.2-3.32.73.22.5-1.0
Condit. Reinf. active minus inactive responses0.70.91.21.0-0.91.10.9-0.9-1.01.00.80.9-1.01.0-1.01.0-0.9-1.0-1.10.2-1.10.91.00.8-0.8
Condit. Reinf. active-inactive response ratio0.30.30.60.3-0.30.50.6-0.6-0.50.50.50.5-0.60.6-0.60.6-0.6-0.6-0.7-0.3-0.80.80.70.6-0.7
Condit. Reinf. active responses1.92.74.22.0-2.02.11.5-1.5-1.81.81.51.5-1.81.8-1.81.6-1.6-1.6-1.60.9-1.71.21.61.4-1.0
Condit. Reinf. inactive responses2.12.64.92.0-2.02.21.4-1.4-1.71.81.41.4-1.71.8-1.81.4-1.5-1.4-1.50.7-1.70.91.81.9-1.5
Condit. Reinf. lever presses1.92.64.61.8-1.82.11.3-1.3-1.61.71.21.2-1.71.8-1.81.3-1.4-1.4-1.60.1-1.81.01.92.1-2.0
Condit. Reinf. lever reinforcers received2.23.15.02.2-2.22.21.6-1.6-1.91.91.61.6-1.92.0-2.01.7-1.6-1.7-1.71.0-1.81.31.81.7-1.2
Conditioned reinforcement - actives0.80.81.90.5-0.30.51.0-1.0-0.80.81.10.9-0.90.8-0.81.0-1.2-1.0-1.10.2-1.01.41.10.7-0.4
Conditioned reinforcement - inactives0.00.10.5-0.20.3-0.30.2-0.20.0-0.10.2-0.0-0.0-0.10.1-0.0-0.2-0.3-0.30.0-0.00.7-0.1-0.10.3
Conditioned locomotion1.21.54.20.7-0.50.71.5-1.5-1.11.11.41.3-1.21.1-1.11.3-1.5-1.6-1.60.5-1.32.01.30.6-0.2
Patch foraging indifference point 0 sec2.03.28.01.2-1.10.72.3-2.3-1.51.52.32.2-1.51.2-1.22.1-1.9-2.0-1.62.8-1.12.30.4-1.42.3
Patch foraging indifference point AUC7.99.112.93.6-3.53.43.2-3.2-3.33.33.02.8-3.23.3-3.33.0-2.9-3.1-3.02.5-2.92.62.92.2-1.1
Delay disc. indifference point, 0s delay1.31.52.6-1.11.0-1.3-1.01.01.3-1.3-1.0-1.11.3-1.41.4-1.31.21.21.3-0.21.4-1.1-1.4-1.61.2
Delay disc. indifference point, 16s delay0.80.83.9-0.80.8-1.0-0.30.30.8-0.9-0.5-0.50.9-1.01.0-0.40.70.60.80.61.1-0.6-1.0-1.52.0
Delay disc. indifference point, 2s delay0.00.00.4-0.10.00.20.0-0.0-0.10.10.00.0-0.10.1-0.1-0.1-0.1-0.1-0.2-0.4-0.20.10.30.3-0.6
Delay disc. indifference point, 24s delay0.40.30.7-0.40.4-0.4-0.70.70.6-0.6-0.7-0.70.6-0.60.6-0.70.70.80.7-0.30.6-0.8-0.4-0.20.1
Delay disc. indifference point, 4s delay0.10.10.2-0.40.2-0.1-0.30.30.3-0.3-0.3-0.20.3-0.30.3-0.40.30.40.3-0.10.4-0.50.1-0.10.2
Delay disc. indifference point, 8s delay0.00.00.20.2-0.10.2-0.00.00.1-0.0-0.0-0.20.0-0.10.1-0.40.10.10.10.10.2-0.30.30.3-0.1
Indifference point function ln k2.33.34.9-2.22.1-2.2-1.81.82.0-2.0-1.7-1.61.9-2.02.0-1.61.71.81.8-1.11.8-1.5-1.9-1.81.1
Indifference point function log k2.33.34.9-2.22.1-2.2-1.81.82.0-2.0-1.7-1.61.9-2.02.0-1.61.71.81.8-1.11.8-1.5-1.9-1.81.1
Patch foraging total patch changes 0 sec2.64.28.21.5-1.51.12.6-2.6-1.91.92.62.6-1.91.6-1.62.4-2.3-2.4-2.02.9-1.62.60.8-1.02.0
Patch foraging total patch changes 12 sec4.25.58.91.9-1.82.02.7-2.7-2.42.42.72.5-2.52.3-2.32.6-2.7-2.8-2.71.7-2.53.02.00.9-0.4
Patch foraging total patch changes 18 sec0.91.21.81.2-1.21.11.3-1.3-1.21.21.21.1-1.11.1-1.11.1-1.1-1.3-1.21.1-1.01.20.80.30.1
Patch foraging total patch changes 24 sec4.35.27.32.2-2.12.02.7-2.7-2.42.42.62.7-2.42.3-2.32.5-2.5-2.6-2.42.2-2.22.51.90.70.2
Patch foraging total patch changes 6 sec5.17.511.22.6-2.52.33.3-3.3-2.92.83.33.2-2.82.6-2.63.0-3.0-3.1-2.83.2-2.53.02.10.50.8
Patch foraging time to switch 0 sec3.85.97.9-2.62.7-2.2-2.82.82.6-2.6-2.6-2.62.5-2.52.5-2.72.52.62.5-2.52.2-2.4-2.0-0.9-0.1
Patch foraging water rate 0 sec4.16.610.32.1-2.11.83.2-3.2-2.62.63.03.1-2.62.4-2.43.1-2.9-2.9-2.82.7-2.43.21.90.20.8
Patch foraging water rate 12 sec0.10.20.70.2-0.2-0.00.5-0.5-0.30.30.40.7-0.30.2-0.20.6-0.4-0.3-0.20.8-0.20.4-0.2-0.70.8
Patch foraging water rate 18 sec1.21.63.30.6-0.50.81.5-1.5-1.21.21.31.6-1.31.2-1.21.6-1.6-1.5-1.60.4-1.51.81.20.5-0.4
Patch foraging water rate 24 sec0.30.41.3-0.10.20.10.5-0.5-0.30.30.30.4-0.40.4-0.40.6-0.7-0.7-0.9-0.7-0.81.21.00.8-1.0
Patch foraging water rate 6 sec0.50.81.40.9-0.90.80.9-0.9-1.01.00.81.2-0.91.0-1.01.2-1.0-0.9-0.80.9-0.90.90.80.40.0
Seeking ratio, delayed vs. immediate footshock4.65.36.82.0-1.92.42.5-2.5-2.42.42.42.4-2.62.4-2.42.3-2.6-2.6-2.51.3-2.42.22.62.0-1.3
Distance traveled before self-admin3.94.26.72.6-2.62.22.3-2.3-2.22.22.22.3-2.12.1-2.12.2-2.0-2.1-1.82.4-1.81.61.40.60.2
Distance traveled after self-admin0.20.31.90.7-0.70.8-0.30.3-0.30.3-0.10.0-0.30.4-0.4-0.10.00.10.0-0.1-0.2-0.50.51.4-1.0
Extensor digitorum longus weight4.618.023.34.8-4.64.64.4-4.4-4.74.74.44.4-4.64.6-4.64.3-4.3-4.3-4.23.6-4.23.64.13.0-1.4
Bone: elastic displacement2.93.37.4-2.72.7-2.3-1.71.72.1-2.1-1.6-1.61.9-2.02.0-1.81.51.61.4-2.11.5-1.0-1.4-1.10.2
Bone: elastic work1.31.77.5-2.12.1-1.3-1.21.21.4-1.3-1.2-1.11.1-1.11.1-1.30.80.80.6-2.70.5-0.2-0.20.4-1.4
Bone: endosteal estimation0.51.12.91.7-1.71.41.0-1.0-1.21.21.00.7-1.01.1-1.10.8-0.8-0.8-0.71.7-0.70.30.70.50.1
Bone: endosteal perimeter0.71.54.01.8-1.81.41.2-1.2-1.41.31.21.0-1.21.2-1.21.1-1.0-1.0-0.92.0-0.80.60.80.30.4
Epididymis fat weight0.20.51.91.3-1.41.00.6-0.6-0.70.70.60.3-0.60.7-0.70.4-0.5-0.5-0.41.1-0.30.00.2-0.0-0.1
Delta time in closed arm before/after self-admin2.12.13.91.4-1.41.91.1-1.1-1.51.51.11.2-1.51.6-1.61.1-1.3-1.3-1.40.0-1.60.91.62.0-2.0
Delta time in open arm before/after self-admin0.50.41.0-0.60.6-0.8-0.50.50.7-0.7-0.6-0.70.7-0.80.8-0.60.70.40.60.20.9-0.3-0.9-0.71.0
Diff in mean of infusions in LGA sessions0.10.10.2-0.30.3-0.2-0.40.40.3-0.3-0.5-0.30.3-0.30.3-0.30.40.30.2-0.40.3-0.3-0.10.1-0.3
Delay discount exponential model param0.30.30.80.5-0.50.50.3-0.3-0.60.60.40.4-0.60.7-0.70.6-0.5-0.5-0.6-0.2-0.80.70.40.7-0.9
Extinction: sum of active levers before priming2.32.33.3-1.51.5-1.3-1.71.71.6-1.6-1.6-1.51.5-1.61.6-1.61.61.71.7-0.71.7-1.8-1.4-0.80.7
Active lever presses in extinction session 60.10.10.5-0.60.6-0.3-0.10.10.2-0.20.00.20.2-0.30.30.2-0.00.10.20.30.2-0.1-0.2-0.30.7
Bone: final force0.50.81.91.3-1.31.40.6-0.6-1.01.00.60.7-0.91.1-1.10.6-0.7-0.7-0.70.4-0.80.21.01.3-0.9
Bone: final moment0.30.51.61.0-1.01.20.3-0.3-0.80.80.30.5-0.70.9-0.90.4-0.4-0.5-0.50.1-0.70.00.91.3-1.0
Food consumed during 24 hour testing period0.40.41.01.0-1.00.90.6-0.6-0.80.80.60.5-0.70.7-0.70.5-0.5-0.4-0.41.0-0.4-0.10.70.70.0
Glucose1.21.72.21.5-1.41.41.4-1.4-1.51.51.41.4-1.41.4-1.41.4-1.4-1.3-1.31.2-1.31.11.30.7-0.3
Heart weight0.50.71.21.0-1.11.10.8-0.8-0.90.90.90.7-0.90.9-0.90.8-0.7-0.8-0.71.1-0.70.40.80.7-0.0
Delay discount hyperbolic model param0.20.30.70.4-0.40.40.3-0.3-0.50.50.30.4-0.50.6-0.60.6-0.5-0.5-0.5-0.2-0.70.60.30.6-0.8
Intermittent access intake day 1-15 change0.50.52.60.4-0.40.70.4-0.4-0.60.60.40.4-0.70.8-0.80.3-0.6-0.5-0.7-0.7-0.90.60.91.2-1.6
Intermittent access intake escalation1.01.02.30.8-0.80.90.9-0.9-1.01.00.80.8-1.01.1-1.10.7-1.0-0.9-1.1-0.3-1.21.01.11.2-1.5
Intermittent access intake escalation 21.31.34.20.7-0.61.00.9-0.9-1.01.00.70.8-1.11.2-1.20.7-1.0-1.1-1.3-0.8-1.41.21.51.8-2.0
Intermitt. access day 1 inactive lever presses0.91.01.60.9-0.91.01.2-1.2-1.01.01.00.9-1.01.0-1.01.0-1.0-1.3-1.20.7-1.01.20.90.6-0.3
Intermitt. access day 15 inactive lever presses0.20.20.90.2-0.1-0.00.7-0.7-0.30.30.50.4-0.40.2-0.20.5-0.4-0.6-0.41.0-0.10.6-0.0-0.50.8
Intermitt. access escalation Index1.00.81.81.3-1.40.91.0-1.0-1.01.01.01.2-0.80.9-0.91.1-0.8-0.6-0.51.2-0.80.3-0.1-0.90.4
Intermittent access day 1 total infusions0.30.42.5-0.30.4-0.50.7-0.7-0.10.10.70.6-0.2-0.10.10.5-0.6-0.6-0.41.0-0.11.0-0.1-0.81.6
Intermittent access day 15 total infusions1.51.73.60.7-0.60.81.6-1.6-1.21.21.61.5-1.41.2-1.21.4-1.6-1.6-1.60.7-1.41.91.10.6-0.2
Intermittent access terminal intake (last 3 days)2.02.25.00.8-0.70.91.9-1.9-1.41.41.81.7-1.61.4-1.41.6-1.8-1.8-1.80.7-1.62.21.30.6-0.2
Intermittent access total infusions2.52.86.21.0-0.91.02.1-2.1-1.61.62.12.0-1.81.5-1.51.9-2.1-2.1-2.01.2-1.72.51.50.60.2
Intermittent access day 1 locomotion0.20.21.6-0.60.7-0.70.4-0.40.2-0.20.40.20.0-0.30.30.2-0.3-0.4-0.30.30.10.90.0-0.41.3
Intermittent access day 15 total locomotion0.20.31.0-0.91.0-0.70.5-0.50.1-0.10.40.4-0.1-0.20.20.3-0.4-0.5-0.4-0.0-0.11.00.1-0.40.8
Intermittent access total locomotion0.30.32.0-0.80.9-0.50.6-0.6-0.10.10.50.5-0.30.1-0.10.3-0.6-0.7-0.8-0.3-0.51.40.60.20.1
Intermittent access standard deviation0.50.51.00.4-0.30.60.8-0.8-0.70.70.70.6-0.80.7-0.70.6-0.8-0.8-0.90.1-0.80.80.91.0-0.7
Left kidney weight0.51.53.11.3-1.21.11.5-1.5-1.31.31.41.3-1.21.2-1.21.4-1.2-1.3-1.11.8-1.01.00.80.00.6
Right kidney weight0.00.10.40.4-0.30.2-0.40.40.2-0.2-0.4-0.50.2-0.20.2-0.40.50.30.40.50.5-0.6-0.10.30.5
Cocaine induced anxiety1.41.62.3-1.21.2-1.5-1.21.21.3-1.3-1.3-1.31.4-1.41.4-1.21.31.21.2-0.71.4-0.8-1.5-1.50.8
Post-drug Anxiety0.10.20.60.8-0.80.2-0.30.3-0.00.0-0.3-0.30.2-0.00.0-0.30.30.30.40.40.4-0.6-0.7-0.40.0
Baseline Anxiety0.91.02.81.3-1.31.50.5-0.5-1.01.00.60.6-1.01.1-1.10.6-0.7-0.6-0.80.0-1.00.21.21.7-1.5
Tail length1.54.510.63.3-3.32.81.9-1.9-2.42.41.71.7-2.22.4-2.31.7-1.7-1.7-1.62.4-1.70.72.11.8-0.6
Length with tail0.52.04.92.2-2.01.71.5-1.5-1.61.61.41.2-1.41.5-1.41.2-1.2-1.2-1.02.2-1.00.50.70.20.4
Length without tail0.20.51.9-0.81.0-0.9-0.30.30.7-0.7-0.3-0.50.7-0.80.8-0.50.40.40.5-0.10.7-0.1-1.2-1.40.9
Times rat made contact with spout0.60.61.10.3-0.20.50.9-0.9-0.80.80.90.9-0.80.8-0.80.8-1.0-0.9-1.0-0.1-1.11.00.80.5-0.8
Lifetime Intake2.52.96.11.1-1.00.92.2-2.2-1.61.62.22.1-1.71.4-1.42.0-2.1-2.1-1.91.7-1.52.51.20.20.9
Liver weight, left0.20.32.30.8-0.80.7-0.60.6-0.00.0-0.5-0.50.20.0-0.0-0.60.50.70.60.20.4-1.5-0.50.2-0.5
Liver weight, right0.40.72.0-0.30.3-0.4-0.90.90.6-0.6-0.8-0.90.8-0.70.7-0.80.91.01.10.20.9-1.4-1.1-0.80.6
Locomotor activity0.00.00.10.1-0.10.1-0.10.10.0-0.0-0.1-0.20.0-0.00.0-0.10.20.10.10.10.2-0.30.10.4-0.0
Locomotor testing distance0.20.31.10.0-0.1-0.3-0.20.20.3-0.3-0.3-0.40.5-0.40.5-0.40.60.50.60.70.8-0.8-0.7-0.81.1
Locomotor testing rearing0.20.31.21.1-1.10.90.6-0.6-0.70.70.50.3-0.50.6-0.60.5-0.4-0.4-0.30.8-0.3-0.00.30.30.1
Locomotion in novel chamber0.10.21.1-0.30.30.3-0.10.1-0.10.1-0.00.1-0.20.2-0.20.1-0.1-0.1-0.2-1.0-0.40.10.50.9-1.1
Locomotion in novel chamber post-restriction1.41.75.11.0-1.11.60.7-0.7-1.21.30.71.2-1.31.5-1.50.9-1.0-1.1-1.4-0.6-1.61.01.72.0-2.3
Fecal boli incidents, locomotor time 10.60.61.4-0.91.0-0.7-0.80.80.9-0.9-0.9-1.20.8-0.80.8-1.10.80.70.6-1.00.7-0.6-0.6-0.0-0.2
Change in fecal boli incidents, locomotor task1.51.42.41.4-1.40.81.5-1.5-1.21.21.41.6-1.11.1-1.11.5-1.2-1.2-1.11.4-1.01.30.7-0.50.7
Time >=10cm from walls, locomotor time 10.30.31.60.3-0.3-0.20.5-0.5-0.20.20.60.5-0.20.1-0.10.7-0.4-0.3-0.11.1-0.00.4-0.7-1.31.1
Bouts of movement, locomotor time 12.02.23.7-1.41.5-1.5-1.51.51.6-1.6-1.7-1.61.6-1.61.6-1.91.71.51.5-1.11.6-1.4-1.2-0.80.4
Total resting periods, locomotor time 12.62.94.9-1.71.8-1.7-1.81.81.8-1.8-2.0-1.81.8-1.81.7-2.21.81.71.6-1.61.7-1.6-1.3-0.60.0
Rest time, locomotor task time 12.73.08.2-1.61.7-1.2-2.12.11.7-1.7-2.2-2.11.6-1.41.4-2.21.81.71.4-2.91.2-1.6-0.50.8-1.8
Distance moved, locomotor task time 12.72.95.71.7-1.91.51.9-1.9-1.81.72.12.1-1.71.6-1.62.3-1.8-1.7-1.42.4-1.41.50.7-0.21.1
Vertical activity count, locomotor time 11.31.44.71.4-1.60.91.2-1.2-1.11.11.41.4-0.90.9-0.91.6-1.1-0.9-0.52.2-0.60.5-0.2-1.01.6
Time >=10cm from walls, locomotor time 20.10.10.30.5-0.40.20.0-0.0-0.20.20.20.3-0.20.2-0.20.3-0.20.00.10.6-0.1-0.20.10.10.2
Bouts of movement, locomotor time 20.50.51.31.1-0.90.90.6-0.6-0.70.80.60.6-0.70.7-0.70.3-0.6-0.6-0.60.8-0.60.41.10.6-0.4
Total resting periods, locomotor time 20.20.30.90.7-0.50.60.4-0.4-0.50.50.40.4-0.50.5-0.50.1-0.4-0.5-0.50.5-0.40.40.90.5-0.3
Rest time, locomotor task time 20.70.81.3-1.11.0-0.9-0.90.91.0-1.0-0.9-1.01.0-0.90.9-1.00.90.70.7-1.00.8-0.5-0.7-0.6-0.0
Distance moved, locomotor task time 20.20.31.80.4-0.50.7-0.20.2-0.30.3-0.1-0.0-0.30.4-0.40.1-0.10.0-0.1-0.5-0.3-0.20.71.3-1.1
Vertical activity count, locomotor time 20.10.10.80.5-0.90.7-0.10.1-0.30.40.20.2-0.20.4-0.30.2-0.20.20.20.4-0.1-0.60.10.4-0.1
Light reinforcement 10.61.17.91.7-1.50.60.7-0.7-0.80.70.80.7-0.50.5-0.40.7-0.3-0.20.22.80.2-0.4-0.6-1.22.2
Light reinforcement 20.91.27.91.2-1.20.10.3-0.3-0.40.30.40.7-0.00.0-0.00.60.00.10.62.80.5-0.7-1.3-2.12.8
Bone: marrow area0.61.23.01.7-1.71.41.1-1.1-1.31.31.10.8-1.11.2-1.20.9-0.9-0.9-0.81.6-0.80.40.80.6-0.1
Bone: maximum diameter1.52.84.62.1-2.12.11.5-1.5-1.91.91.51.3-1.81.9-1.91.5-1.5-1.5-1.51.3-1.71.01.71.6-1.2
Bone: maximum force1.72.95.62.2-2.22.41.3-1.3-1.81.91.31.5-1.71.9-1.91.3-1.4-1.4-1.40.7-1.60.82.02.2-1.5
Bone: maximum moment1.22.14.51.9-1.82.11.0-1.0-1.51.61.01.2-1.51.7-1.71.0-1.1-1.2-1.20.4-1.40.61.82.1-1.6
Mean time between licks in bursts1.82.64.9-0.80.8-1.0-2.12.11.6-1.5-2.1-2.01.7-1.51.5-2.02.01.91.9-1.21.7-2.2-1.3-0.2-0.1
Mean num. licks in bursts1.72.13.7-1.81.9-1.8-1.31.31.6-1.6-1.3-1.41.5-1.61.6-1.51.31.41.3-1.21.5-1.1-1.2-1.00.7
Cd content in liver0.40.42.10.6-0.50.70.2-0.2-0.50.50.20.2-0.50.6-0.60.2-0.3-0.3-0.4-0.5-0.60.21.01.5-1.3
Co content in liver1.61.83.4-1.21.2-1.6-1.21.21.3-1.4-1.3-1.21.4-1.41.4-1.21.41.31.4-0.31.5-1.1-1.8-1.81.3
Cu content in liver2.02.53.5-1.51.4-1.3-1.91.91.6-1.6-1.9-1.81.6-1.51.5-1.81.71.81.6-1.61.4-1.8-1.4-0.5-0.4
Fe content in liver0.40.52.50.7-0.6-0.3-0.30.30.2-0.2-0.3-0.30.4-0.40.4-0.30.60.50.81.30.9-0.8-1.1-1.41.6
K content in liver0.40.40.8-0.40.3-0.6-0.50.50.6-0.6-0.5-0.50.6-0.60.6-0.50.60.70.80.20.7-0.7-0.8-0.80.9
Mg content in liver0.20.30.7-0.60.5-0.6-0.40.40.5-0.5-0.3-0.30.5-0.60.6-0.30.40.50.5-0.20.5-0.3-0.7-0.80.6
Mn content in liver0.20.21.20.3-0.40.60.1-0.1-0.30.30.10.1-0.40.4-0.40.1-0.3-0.2-0.4-0.6-0.50.10.50.9-1.1
Na content in liver3.84.05.8-1.51.4-1.6-2.42.42.0-2.0-2.3-2.32.1-1.92.0-2.32.32.32.3-1.42.1-2.4-1.9-1.10.3
Rb content in liver4.05.07.5-2.72.6-2.7-2.12.12.4-2.4-2.1-2.12.4-2.42.4-2.12.22.22.2-1.52.2-1.8-2.3-2.01.4
Se content in liver0.91.13.61.7-1.81.90.3-0.3-1.01.00.30.3-1.01.1-1.10.3-0.5-0.5-0.60.1-0.8-0.21.31.9-1.7
Sr content in liver0.40.31.31.1-1.11.10.3-0.3-0.60.60.30.3-0.60.6-0.60.3-0.3-0.4-0.40.3-0.40.00.40.5-0.7
Zn content in liver0.20.21.7-0.10.10.30.1-0.1-0.20.30.00.1-0.30.4-0.40.1-0.3-0.2-0.4-0.7-0.50.40.81.3-1.1
Bone: minimum diameter0.00.10.2-0.20.2-0.1-0.20.20.2-0.2-0.2-0.50.2-0.10.1-0.30.20.10.1-0.40.1-0.00.20.4-0.5
Time in familiar zone, hab. session 10.60.64.0-0.80.8-0.2-0.00.00.2-0.1-0.0-0.0-0.10.1-0.1-0.1-0.3-0.3-0.6-2.0-0.70.90.81.0-1.9
Time in novel zone, hab. session 14.24.17.4-0.90.9-1.6-1.91.91.8-1.8-1.9-1.92.0-2.02.0-1.92.32.22.50.72.6-2.7-2.5-2.22.5
Total zone transitions, hab. session 10.00.10.20.2-0.20.1-0.30.30.1-0.1-0.3-0.20.1-0.10.1-0.20.30.30.3-0.10.2-0.50.10.4-0.2
Total locomotion distance, hab. session 10.40.52.90.6-0.60.90.1-0.1-0.40.50.10.1-0.50.6-0.60.1-0.3-0.3-0.4-0.7-0.6-0.01.01.6-1.7
Locomotion velocity, hab. session 11.21.74.51.5-1.61.80.8-0.8-1.31.30.90.9-1.31.4-1.40.9-1.0-1.0-1.1-0.0-1.40.51.72.1-1.9
Time in familiar zone, hab. session 20.80.83.2-1.01.0-0.6-1.11.10.9-0.9-1.0-0.90.8-0.70.7-1.00.80.90.6-1.80.4-0.6-0.40.3-1.1
Time in novel zone, hab. session 21.31.34.7-0.90.9-1.4-0.60.61.0-1.0-0.7-0.81.1-1.21.2-0.71.00.91.20.71.4-0.9-1.4-1.92.2
Total zone transitions, hab. session 20.30.41.41.2-1.20.90.5-0.5-0.70.70.50.6-0.60.6-0.60.6-0.5-0.4-0.31.1-0.40.00.50.40.3
Total locomotion distance, hab. session 20.60.81.71.2-1.21.30.7-0.7-1.01.00.80.8-0.91.0-1.00.7-0.8-0.8-0.70.6-0.80.41.11.2-0.6
Locomotion velocity, hab. session 20.91.22.31.4-1.41.51.0-1.0-1.21.21.01.0-1.21.2-1.20.9-1.0-1.0-1.00.6-1.10.51.31.4-0.8
Novel to familiar place preference ratio3.13.25.7-1.81.9-2.2-1.41.41.8-1.8-1.5-1.51.9-2.02.0-1.51.71.61.8-0.02.0-1.3-2.2-2.42.2
Novelty place preference4.14.16.3-2.22.2-2.5-1.71.72.1-2.1-1.8-1.82.1-2.32.3-1.72.01.92.0-0.42.3-1.5-2.4-2.52.2
Time in novel zone, NPP test5.35.47.9-2.42.5-2.8-2.02.02.4-2.4-2.1-2.12.5-2.62.6-2.02.32.22.4-0.52.6-1.8-2.7-2.82.4
Total zone transitions, NPP test0.40.51.91.3-1.31.00.6-0.6-0.80.70.50.6-0.60.7-0.60.6-0.4-0.4-0.21.4-0.3-0.10.40.30.5
Total locomotion distance, NPP test1.92.64.22.0-2.11.91.8-1.8-1.81.81.71.8-1.71.7-1.61.7-1.6-1.6-1.41.9-1.41.11.30.70.2
Locomotion velocity, NPP test2.73.85.22.3-2.32.22.1-2.1-2.12.12.02.1-2.12.0-2.02.0-2.0-2.0-1.91.9-1.81.51.81.2-0.2
Intraocular pressure2.94.16.42.1-2.21.82.2-2.2-2.22.22.52.5-2.12.1-2.12.3-2.1-2.0-1.92.2-1.91.91.40.60.3
Delta distance traveled before/after self-admin1.81.93.5-1.01.0-0.9-1.91.91.4-1.4-1.6-1.71.4-1.31.3-1.71.61.71.6-1.31.3-1.8-1.00.1-0.3
Delta ambulatory time before/after self-admin3.63.96.5-1.61.6-1.5-2.62.62.0-2.0-2.3-2.22.0-1.91.9-2.32.22.42.2-1.81.9-2.5-1.5-0.1-0.2
Parametrial fat weight0.10.10.70.8-0.70.40.3-0.3-0.30.30.20.2-0.20.3-0.30.2-0.2-0.1-0.00.8-0.0-0.20.00.20.4
Pavlov. Cond. lever latency6.38.012.0-3.53.4-3.3-2.72.73.2-3.2-2.7-3.03.1-3.13.1-2.92.82.72.7-2.42.8-2.2-2.7-2.21.1
Pavlov. Cond. magazine entry latency0.20.21.00.8-0.80.80.1-0.1-0.50.50.10.2-0.50.5-0.50.2-0.2-0.2-0.30.0-0.4-0.10.61.0-0.8
Pavlov. Cond. change in total contacts2.32.43.51.9-1.81.81.5-1.5-1.71.71.51.6-1.71.7-1.71.5-1.5-1.5-1.51.3-1.51.31.51.2-0.6
Pavlov. Cond. index score2.22.85.02.2-2.22.21.3-1.3-1.91.91.31.5-1.81.9-1.91.4-1.4-1.4-1.51.0-1.70.91.82.0-1.3
Pavlov. Cond. latency score2.22.84.62.1-2.12.11.4-1.4-1.91.91.41.6-1.81.9-1.91.5-1.5-1.5-1.51.1-1.71.11.81.9-1.2
Pavlov. Cond. lever contacts5.36.28.22.9-2.82.92.3-2.3-2.72.72.42.6-2.72.7-2.72.5-2.5-2.4-2.41.8-2.62.02.52.1-1.1
Pavlov. Cond. magazine entry number0.40.51.3-1.01.0-1.0-0.50.50.8-0.8-0.5-0.60.8-0.90.8-0.50.50.50.6-0.30.7-0.2-0.9-1.20.8
Pavlov. Cond. intertrial magazine entries0.10.20.40.6-0.60.60.3-0.3-0.50.50.30.3-0.40.5-0.50.3-0.3-0.4-0.30.3-0.40.20.40.4-0.4
Pavlov. Cond. lever-magazine prob. diff.2.12.74.72.1-2.02.21.2-1.2-1.81.81.21.5-1.81.9-1.91.4-1.4-1.3-1.50.7-1.71.01.92.1-1.5
Pavlov. Cond. response bias2.53.04.82.2-2.22.21.5-1.5-1.91.91.51.7-1.92.0-2.01.6-1.6-1.5-1.61.2-1.71.11.91.8-1.0
Pavlov. Cond. lever latency2.02.74.5-1.91.8-2.1-1.31.31.7-1.7-1.3-1.11.7-1.81.8-1.31.41.41.6-0.11.8-1.1-1.9-2.12.1
Pavlov. Cond. magazine entry latency1.31.52.5-0.70.9-0.8-1.51.51.2-1.2-1.5-1.61.2-1.11.1-1.61.51.31.3-1.21.2-1.4-0.9-0.0-0.4
Pavlov. Cond. change in total contacts0.50.75.20.8-0.71.10.0-0.0-0.50.5-0.1-0.0-0.50.7-0.70.0-0.2-0.2-0.5-1.2-0.8-0.11.01.7-2.3
Pavlov. Cond. index score0.20.32.30.3-0.20.5-0.30.3-0.00.0-0.4-0.5-0.00.2-0.2-0.40.20.1-0.0-1.0-0.2-0.30.41.1-1.5
Pavlov. Cond. latency score0.30.42.90.4-0.30.7-0.00.0-0.30.3-0.1-0.2-0.30.4-0.4-0.1-0.1-0.2-0.4-0.9-0.50.00.81.3-1.7
Pavlov. Cond. lever contacts0.91.32.41.5-1.41.50.9-0.9-1.21.20.80.7-1.21.3-1.30.8-0.9-1.0-1.10.2-1.20.71.21.4-1.5
Pavlov. Cond. magazine entry number0.40.42.50.2-0.3-0.10.7-0.7-0.40.30.70.9-0.30.2-0.20.8-0.5-0.3-0.21.4-0.10.4-0.2-1.01.6
Pavlov. Cond. intertrial magazine entries0.81.11.80.8-0.80.81.2-1.2-1.11.11.21.3-1.11.1-1.11.3-1.2-1.1-1.10.8-1.11.10.90.30.0
Pavlov. Cond. lever-magazine prob. diff.0.30.32.60.3-0.10.4-0.40.40.0-0.0-0.5-0.60.00.1-0.1-0.50.30.2-0.0-1.1-0.1-0.40.41.2-1.6
Pavlov. Cond. response bias0.30.42.10.8-0.80.90.1-0.1-0.50.50.1-0.1-0.50.6-0.60.0-0.2-0.3-0.4-0.4-0.50.10.71.2-1.4
Time in closed arm before self-admin1.41.63.7-1.81.8-1.9-1.11.11.4-1.4-1.1-1.11.3-1.51.4-1.01.01.11.0-1.01.2-0.3-1.0-1.30.9
Time in closed arm after self-admin0.10.10.6-0.50.5-0.3-0.30.30.2-0.2-0.2-0.20.2-0.20.2-0.20.10.20.1-0.8-0.00.1-0.10.2-0.5
Time in open arm before self-admin1.82.04.02.0-2.01.61.3-1.3-1.61.61.61.6-1.41.5-1.51.5-1.4-1.1-1.01.8-1.20.60.90.30.3
Time in open arm after self-admin1.61.83.21.4-1.41.21.6-1.6-1.41.41.51.5-1.41.3-1.31.5-1.4-1.5-1.31.8-1.11.31.00.20.6
Bone: periosteal estimation0.81.73.31.8-1.81.71.2-1.2-1.51.51.20.9-1.31.5-1.51.0-1.1-1.2-1.11.3-1.20.61.31.2-0.8
Bone: periosteal perimeter0.30.51.71.1-1.00.80.7-0.7-0.80.80.70.5-0.70.7-0.70.6-0.6-0.6-0.51.3-0.40.30.50.20.3
Bone: post-yield work0.71.03.21.8-1.71.50.8-0.8-1.11.10.70.9-1.01.1-1.00.8-0.6-0.7-0.51.4-0.60.00.70.70.0
Progressive ratio test 1 active lever presses2.12.26.00.5-0.40.31.9-1.9-1.21.22.11.9-1.41.0-1.11.8-1.9-1.8-1.71.5-1.32.40.7-0.31.2
Progressive ratio test 1 breakpoint2.32.46.20.7-0.60.52.0-2.0-1.31.32.11.9-1.51.2-1.21.9-2.0-1.9-1.81.5-1.42.50.9-0.21.1
Progressive ratio test 1 inactive lever presses1.31.43.91.0-0.90.41.5-1.5-1.01.01.61.4-1.00.8-0.81.4-1.3-1.3-1.02.0-0.71.50.2-1.01.7
Progressive ratio test 2 active lever presses0.70.71.90.2-0.1-0.11.1-1.1-0.60.51.21.1-0.70.4-0.41.0-1.0-0.9-0.81.2-0.51.30.1-0.81.4
Progressive ratio test 2 breakpoint0.50.62.1-0.00.2-0.31.0-1.0-0.40.41.11.0-0.50.2-0.20.9-0.9-0.7-0.61.0-0.41.2-0.0-0.81.4
Progressive ratio test 2 inactive lever presses0.70.82.50.5-0.40.41.1-1.1-0.80.81.01.0-0.90.7-0.70.9-1.0-1.2-1.10.7-0.81.60.70.30.3
Incentive Sensitization - Responses0.10.10.7-0.10.1-0.20.3-0.3-0.00.00.40.3-0.1-0.10.10.2-0.2-0.1-0.00.50.10.2-0.2-0.70.9
Incentive Sensitization - Breakpoint0.10.10.8-0.20.2-0.40.2-0.20.0-0.10.30.30.0-0.20.20.2-0.1-0.00.00.50.10.2-0.3-0.90.9
Sum of active levers in priming session hrs 5-62.12.03.2-1.71.7-1.8-1.11.11.5-1.5-1.1-0.81.4-1.61.6-1.01.21.41.4-0.21.5-1.2-1.7-1.81.8
Progressive ratio0.00.00.0-0.20.2-0.2-0.20.20.1-0.1-0.2-0.10.1-0.10.1-0.10.10.10.10.10.20.00.00.10.2
Food seeking constrained by brief footshock8.710.714.83.5-3.63.13.7-3.7-3.53.53.93.6-3.43.3-3.33.8-3.5-3.5-3.23.7-3.03.02.30.80.5
Seeking ratio, punishment vs. effort2.22.73.91.8-1.91.71.9-1.9-1.81.82.01.9-1.71.7-1.71.8-1.8-1.8-1.61.6-1.61.41.00.30.0
Retroperitoneal fat weight0.20.50.9-0.60.6-0.5-0.90.90.7-0.7-1.0-1.00.7-0.70.7-0.90.90.80.7-0.70.7-0.8-0.40.1-0.2
Reaction time number correct0.20.30.80.3-0.40.30.6-0.6-0.60.60.60.9-0.60.5-0.50.7-0.7-0.6-0.50.8-0.50.60.3-0.20.6
Reaction time mean minus median0.70.97.40.4-0.21.0-0.30.3-0.40.4-0.3-0.0-0.50.7-0.70.1-0.1-0.1-0.4-1.6-0.9-0.11.12.2-2.7
Reaction time mean minus median AUC0.91.25.61.1-0.81.40.3-0.3-0.90.90.20.5-1.01.1-1.10.7-0.6-0.7-0.9-0.8-1.20.41.42.1-2.4
Reaction time num false alarms0.10.21.30.0-0.10.4-0.10.10.00.0-0.2-0.3-0.00.1-0.1-0.40.1-0.1-0.2-0.7-0.1-0.00.71.2-1.0
Reaction time num false alarms AUC0.30.51.40.7-0.80.90.6-0.6-0.60.60.50.4-0.60.7-0.70.3-0.5-0.8-0.70.1-0.60.61.11.2-0.7
Reaction time trials correct on left0.20.30.80.3-0.40.30.6-0.6-0.60.60.60.9-0.60.5-0.50.7-0.7-0.6-0.50.8-0.50.60.3-0.20.6
Reaction time trials on left0.10.20.60.2-0.30.20.5-0.5-0.40.40.50.8-0.40.4-0.40.6-0.5-0.5-0.40.7-0.40.50.2-0.20.6
Reaction time mean2.33.26.6-1.61.7-1.2-2.32.31.8-1.7-2.3-2.11.7-1.51.5-1.92.01.91.7-2.61.3-1.9-0.80.6-1.5
Reaction time mean AUC2.53.37.0-1.71.9-1.3-2.32.31.8-1.8-2.3-2.11.7-1.61.5-1.92.01.91.7-2.61.4-1.9-0.80.6-1.5
Median of all reaction times4.05.58.2-2.22.3-2.1-2.92.92.5-2.5-2.8-2.72.5-2.32.3-2.52.62.62.4-2.52.2-2.4-1.7-0.4-0.5
Reaction time omissions2.02.74.0-1.51.5-1.5-2.02.01.7-1.7-1.9-1.91.7-1.71.7-1.71.91.81.8-1.21.8-1.8-1.4-0.50.2
Reaction time false alarm rate0.10.10.7-0.10.00.2-0.30.30.2-0.2-0.4-0.50.2-0.10.1-0.50.30.10.0-0.80.1-0.10.40.9-0.8
Reaction time premature initiation rate1.31.84.9-2.02.2-1.8-1.21.21.5-1.5-1.2-1.11.3-1.41.4-1.21.11.10.9-1.90.9-0.3-1.2-1.1-0.1
Reaction time premature initiations0.60.93.3-1.61.8-1.5-0.70.71.0-1.0-0.7-0.50.9-1.01.0-0.60.60.60.5-1.20.50.1-0.9-1.00.2
Std. dev. reaction times0.81.15.0-0.40.60.1-1.31.30.7-0.6-1.4-1.10.6-0.40.4-1.01.00.90.6-2.00.3-1.10.31.7-2.2
Reaction time trials completed0.10.20.60.2-0.30.20.5-0.5-0.40.40.50.8-0.40.4-0.40.6-0.5-0.5-0.40.7-0.40.50.2-0.20.6
Reaction time trials AUC0.10.20.60.2-0.20.20.5-0.5-0.50.40.50.8-0.50.4-0.40.6-0.6-0.5-0.40.6-0.40.50.2-0.20.6
Run reversals in cocaine runway, females0.20.11.40.2-0.10.2-0.30.3-0.10.1-0.2-0.3-0.10.2-0.20.10.00.1-0.1-0.9-0.40.00.40.6-1.2
Run reversals in cocaine runway, males0.00.00.1-0.30.3-0.10.1-0.1-0.10.10.10.3-0.20.1-0.10.1-0.2-0.1-0.2-0.1-0.20.30.30.2-0.1
Latency to leave start box in cocaine runway0.70.81.20.7-0.70.80.9-0.9-0.90.90.91.0-1.01.0-1.00.8-1.0-1.0-1.10.2-1.01.11.10.7-0.7
Latency to leave start box in cocaine runway, F0.00.00.1-0.10.1-0.10.2-0.2-0.10.10.20.2-0.10.0-0.10.2-0.2-0.1-0.20.2-0.10.30.2-0.10.2
Latency to leave start box in cocaine runway, M1.21.22.01.3-1.41.11.2-1.2-1.21.21.21.3-1.11.1-1.11.2-1.1-1.1-1.01.1-1.01.00.70.10.0
Std. dev. time between licks in bursts0.70.81.2-0.70.6-0.7-1.11.10.9-0.9-1.1-1.11.0-0.90.9-1.11.11.01.0-0.71.0-1.0-0.50.00.1
Total sessions with >9 infusions0.70.83.60.4-0.2-0.21.1-1.1-0.50.41.20.9-0.50.2-0.20.9-0.9-0.9-0.61.6-0.21.3-0.0-0.91.9
Short access day 1 total inactive lever presses3.64.07.11.6-1.61.52.5-2.5-2.01.92.42.2-2.01.8-1.92.3-2.3-2.4-2.31.7-2.02.71.70.30.3
Short access day 10 total inactive lever presses0.10.10.20.5-0.40.30.4-0.4-0.30.30.20.1-0.20.3-0.30.1-0.2-0.4-0.30.2-0.20.3-0.0-0.2-0.2
Short access day 1 total infusions2.42.64.61.4-1.30.92.1-2.1-1.51.42.01.8-1.51.2-1.21.8-1.8-1.9-1.62.1-1.22.11.0-0.41.4
Short access day 10 total infusions1.71.94.11.1-0.90.61.7-1.7-1.31.21.81.8-1.31.1-1.11.6-1.7-1.6-1.41.7-1.12.00.8-0.21.2
Short access total infusions1.11.22.80.7-0.60.31.4-1.4-0.90.81.51.3-0.90.6-0.61.2-1.3-1.3-1.01.7-0.71.60.4-0.51.7
Short access day 1 locomotion0.10.10.6-0.20.2-0.20.3-0.30.0-0.10.30.1-0.1-0.10.10.1-0.3-0.3-0.30.1-0.00.70.2-0.20.8
Short access day 10 total locomotion0.40.41.2-1.01.0-0.7-0.60.60.6-0.6-0.6-0.70.5-0.60.5-0.80.50.30.2-1.10.30.20.30.6-0.4
Short access total locomotion0.30.31.40.4-0.30.10.7-0.7-0.40.40.60.5-0.40.3-0.30.4-0.6-0.8-0.70.6-0.31.20.50.00.7
One hour access (0.3 mA shock)1.41.73.01.1-1.00.81.6-1.6-1.31.31.71.6-1.31.2-1.21.6-1.6-1.5-1.31.4-1.21.60.80.10.5
Compulsive drug intake0.30.30.70.7-0.80.80.5-0.5-0.60.60.60.5-0.60.6-0.60.6-0.5-0.3-0.30.6-0.5-0.20.00.2-0.2
One hour access (shock baseline)1.71.94.90.8-0.60.41.8-1.8-1.21.21.81.7-1.31.0-1.01.7-1.6-1.7-1.61.5-1.22.21.0-0.10.9
Social response proportion4.54.97.7-1.91.6-1.7-2.82.82.3-2.3-2.7-2.62.3-2.12.1-2.62.52.52.4-2.32.1-2.5-1.7-0.4-0.4
Social responses0.20.31.11.0-1.10.90.1-0.1-0.50.50.10.2-0.40.6-0.60.1-0.2-0.3-0.30.2-0.30.00.61.0-0.7
Social time1.82.47.1-0.20.2-0.6-2.02.01.3-1.3-1.9-1.81.5-1.31.3-1.82.02.02.1-0.71.8-2.7-1.3-0.1-0.0
Soleus weight0.51.66.50.3-0.3-0.5-0.80.80.6-0.7-0.8-0.71.0-0.90.9-0.71.21.21.62.01.6-1.9-1.7-1.82.6
Bone: stiffness1.72.76.52.5-2.52.51.0-1.0-1.81.81.01.0-1.61.9-1.91.1-1.0-1.2-1.10.8-1.40.31.82.4-1.7
Tibialis anterior weight5.820.030.35.5-5.34.94.6-4.6-5.05.04.64.7-4.84.9-4.84.6-4.4-4.4-4.14.6-4.23.44.02.7-0.9
Time to tail flick, vehicle, before self-admin0.60.61.7-1.31.3-1.1-0.50.50.9-0.9-0.7-0.60.8-0.90.9-0.60.60.70.5-0.70.7-0.3-0.5-0.90.4
Time to tail flick, vehicle, after self-admin0.10.10.3-0.10.1-0.20.3-0.3-0.10.10.30.5-0.20.1-0.10.3-0.2-0.3-0.20.3-0.10.5-0.1-0.50.4
Time to tail flick, test, before self-admin0.50.51.10.5-0.50.50.8-0.8-0.70.70.70.7-0.70.8-0.80.7-0.9-0.9-0.90.1-0.91.00.80.2-0.6
Time to tail flick, test, after self-admin1.31.42.30.6-0.60.91.1-1.1-1.11.11.11.0-1.21.2-1.21.1-1.3-1.3-1.4-0.1-1.51.51.51.2-1.3
Delta time to tail flick, vehicle, before/after SA0.00.00.20.5-0.50.30.0-0.0-0.30.30.20.1-0.20.3-0.20.1-0.0-0.2-0.00.2-0.10.1-0.10.1-0.2
Delta time to tail flick, test, before/after SA0.00.00.2-0.40.4-0.1-0.00.00.1-0.1-0.0-0.10.1-0.10.10.00.00.0-0.1-0.4-0.00.10.20.4-0.2
Tibia length0.41.23.10.1-0.1-0.6-1.21.20.7-0.8-1.2-1.01.0-0.90.9-1.11.41.31.50.81.5-1.8-1.3-0.91.4
Ambulatory time before self-admin3.73.86.22.3-2.31.92.3-2.3-2.12.12.22.3-2.01.9-1.92.2-2.0-2.1-1.82.5-1.61.61.30.40.6
Ambulatory time after self-admin0.10.10.60.5-0.50.5-0.30.3-0.10.1-0.10.1-0.10.1-0.1-0.10.20.20.30.40.1-0.70.10.80.0
Bone: tissue strength0.60.62.10.3-0.30.3-1.11.10.4-0.4-1.1-0.80.5-0.30.3-0.90.90.90.9-0.80.6-1.4-0.30.7-0.8
Total heroin consumption0.40.42.7-0.50.5-0.6-0.20.20.4-0.4-0.10.30.4-0.60.6-0.10.20.40.50.80.7-0.4-0.9-1.31.7
Bone: trabecular number1.32.02.81.3-1.41.51.3-1.3-1.51.51.31.4-1.51.6-1.61.3-1.5-1.5-1.50.2-1.61.51.71.5-1.3
Bone: trabecular spacing0.00.10.5-0.20.20.0-0.20.20.1-0.1-0.1-0.20.1-0.00.0-0.20.00.0-0.1-0.6-0.10.00.20.4-0.7
Bone: trabecular thickness0.00.00.1-0.20.2-0.2-0.20.20.2-0.2-0.2-0.10.2-0.20.2-0.20.20.10.2-0.40.1-0.1-0.2-0.1-0.1
Bone: trabecular tissue density0.91.24.52.1-2.11.80.6-0.6-1.21.20.60.5-1.01.2-1.20.5-0.5-0.5-0.51.0-0.7-0.30.91.5-1.0
Water consumed over 24 hours1.01.21.70.8-0.70.91.3-1.3-1.21.11.31.2-1.21.2-1.21.1-1.3-1.2-1.30.5-1.31.21.10.6-0.5
Number of responses in last shaping day0.60.63.80.7-0.70.00.7-0.7-0.40.30.70.8-0.30.1-0.10.8-0.4-0.3-0.11.70.00.3-0.6-1.22.0