Tln1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Tln1 0.11 0.09 1.8e-05 0.03 -0 0.02 0.01 7.6e-05 4.7e-01 1.3e-04 3.4e-03
2 pVTA isoform ratio XM_063287730.1 0.1 0.08 3.0e-04 0.05 0.05 0.04 0.05 7.7e-05 8.5e-05 3.3e-04 1.2e-04
3 NAcc mRNA stability Tln1 0.02 0.01 2.0e-03 0.01 0.01 0.01 0 6.1e-03 3.5e-02 2.7e-03 1.6e-01
4 PL isoform ratio NM_001039025.2 0.03 0.03 3.9e-04 0.03 0.03 0.04 0.03 3.1e-04 2.0e-04 5.3e-05 1.1e-04
5 PL alternative TSS NM_001039025.2 0.03 0.02 1.4e-03 0.03 0.02 0.03 0.02 6.6e-04 1.6e-03 6.0e-04 1.4e-03
6 NAcc isoform ratio NM_001039025.2 0.03 0.02 1.0e-05 0.03 0.01 0.02 0 2.2e-05 9.2e-03 1.4e-04 3.9e-01
7 NAcc isoform ratio XM_063287730.1 0.03 0.02 1.7e-05 0.03 0.01 0.02 0 5.3e-05 6.0e-03 1.7e-04 1.5e-01
8 Liver isoform ratio NM_001039025.2 0.08 0.05 1.2e-11 0.11 0.1 0.1 0.1 3.9e-12 1.2e-11 3.1e-11 1.1e-11
9 Liver isoform ratio XM_063287730.1 0.08 0.05 3.3e-11 0.11 0.1 0.1 0.1 8.5e-12 3.6e-11 7.9e-11 3.0e-11
10 PL intron excision ratio chr5_62607846_62613140 0.02 0.01 7.6e-03 0.01 0.01 0 0.01 2.6e-02 2.6e-02 1.1e-01 4.9e-02
11 PL intron excision ratio chr5_62610799_62613140 0.02 0.01 3.6e-03 0.02 0.01 0.02 0.01 3.9e-03 9.4e-03 6.6e-03 8.3e-03
12 PL isoform ratio XM_063287730.1 0.03 0.03 3.5e-04 0.03 0.03 0.04 0.03 3.2e-04 2.1e-04 5.3e-05 1.2e-04
13 pVTA isoform ratio NM_001039025.2 0.14 0.11 1.7e-04 0.05 0.05 0.05 0.05 7.1e-05 5.8e-05 8.1e-05 1.1e-04
14 Liver intron excision ratio chr5_62599188_62600150 0.39 0.26 0.0e+00 0.24 0.26 0.24 0.26 2.2e-26 3.6e-28 1.9e-26 3.0e-28
15 Adipose gene expression Tln1 0.11 0.07 1.2e-08 0.03 0.06 0.06 0.05 2.0e-04 6.4e-07 3.0e-07 3.0e-06
16 Liver intron excision ratio chr5_62599761_62600150 0.16 0.09 0.0e+00 0.17 0.18 0.17 0.18 1.1e-18 7.0e-20 5.7e-19 8.9e-20
17 Liver intron excision ratio chr5_62599188_62599711 0.56 0.26 0.0e+00 0.22 0.22 0.23 0.22 9.9e-24 1.2e-24 4.4e-25 2.2e-24
18 Liver gene expression Tln1 0.08 0.05 2.0e-06 0.02 0.04 0.04 0.03 4.6e-03 3.2e-05 6.5e-05 1.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density1.52.63.9-1.3-1.3-1.71.51.71.7-1.71.8-1.8-1.71.7-1.00.62.0-1.4-1.9-1.9-1.6
Area under the delay curve0.80.91.90.60.60.9-0.5-1.2-1.21.2-1.01.01.4-1.40.2-0.2-1.00.41.00.91.0
BMI with tail1.65.77.6-2.3-2.3-2.62.42.52.7-2.72.5-2.5-2.42.4-1.41.32.8-2.5-2.7-2.7-1.7
BMI without tail2.16.58.9-2.8-2.7-2.92.72.73.0-3.02.6-2.6-2.72.7-2.02.02.5-2.4-2.4-2.3-1.4
Body weight2.812.318.2-4.3-4.2-4.04.03.73.5-3.53.4-3.4-3.53.5-3.23.63.3-3.8-2.8-3.2-0.7
Weight adjusted by age0.10.20.7-0.5-0.8-0.40.60.40.0-0.00.2-0.2-0.40.4-0.60.70.1-0.9-0.0-0.40.5
Bone surface0.81.51.9-1.2-1.2-1.41.31.31.2-1.21.3-1.3-1.31.3-0.90.91.4-1.2-1.2-1.3-0.6
Bone volume0.71.32.0-1.0-0.9-1.21.11.21.2-1.21.3-1.3-1.21.2-0.70.51.4-1.0-1.4-1.4-1.0
Breakpoint value in progressive ratio session2.22.69.90.30.10.9-0.6-1.3-2.02.0-2.02.01.5-1.50.50.6-1.90.22.41.73.1
Number of licking bursts3.55.67.5-2.4-2.3-2.52.32.62.7-2.72.5-2.5-2.62.6-2.01.62.5-2.0-2.4-2.2-1.6
Context. condit. distance diff. score0.10.10.40.50.40.3-0.4-0.3-0.20.2-0.20.20.2-0.20.5-0.6-0.00.2-0.1-0.0-0.2
Locomotion velocity, session 11.11.17.2-1.1-1.2-0.51.0-0.1-0.30.3-0.30.30.5-0.5-0.92.1-0.6-1.21.30.32.7
Locomotion distance, session 10.30.42.0-0.8-0.9-0.40.70.20.1-0.1-0.10.10.1-0.1-0.71.4-0.3-0.70.60.21.4
Locomotion velocity, session 22.83.24.0-1.6-1.7-1.91.82.01.9-1.92.0-2.0-1.91.9-1.31.02.0-1.6-2.0-2.0-1.5
Locomotion distance, session 21.62.36.5-2.0-1.9-1.71.81.51.5-1.51.2-1.2-1.41.4-2.22.50.5-1.2-0.3-0.40.6
Locomotion velocity, session 30.30.31.8-0.4-0.4-0.10.3-0.2-0.30.3-0.40.40.4-0.4-0.30.9-0.5-0.30.80.51.3
Locomotion distance, session 31.71.93.6-1.8-1.8-1.61.71.31.2-1.21.1-1.1-1.11.1-1.11.51.4-1.9-1.0-1.40.2
Stereotopy head waving bouts, day 30.50.63.00.00.10.4-0.1-0.6-0.70.7-0.70.70.7-0.7-0.40.8-1.10.11.41.01.7
Stereotopy head waving duration, day 30.50.61.30.40.50.7-0.5-0.7-0.80.8-0.70.70.7-0.7-0.00.2-1.10.61.11.11.2
Locomotion velocity, session 70.10.10.20.40.30.3-0.3-0.4-0.20.2-0.40.40.4-0.40.4-0.3-0.30.30.30.30.1
Locomotion distance, session 70.10.20.4-0.5-0.5-0.60.50.30.3-0.30.3-0.3-0.30.3-0.30.60.3-0.6-0.1-0.30.3
Stereotopy head waving bouts, day 71.01.22.2-1.3-1.3-1.21.41.00.9-0.91.0-1.0-0.90.9-1.21.21.0-1.5-0.7-1.10.2
Stereotopy head waving duration, day 70.50.61.4-1.0-1.0-0.81.00.80.7-0.70.8-0.8-0.70.7-1.21.10.4-0.8-0.3-0.50.2
Locomotion velocity, session 80.40.41.8-0.3-0.20.00.2-0.2-0.20.2-0.40.40.2-0.2-0.71.2-1.10.31.21.01.4
Locomotion distance, session 80.20.31.4-0.6-0.6-0.40.60.20.3-0.30.0-0.0-0.10.1-0.81.2-0.3-0.40.50.31.0
Degree of sensitization distance1.01.11.91.31.21.1-1.2-1.0-1.01.0-0.90.90.9-0.90.7-0.7-1.31.41.11.30.3
Degree of sensitization stereotypy1.31.42.2-1.3-1.3-1.31.41.21.1-1.11.2-1.2-1.11.1-1.00.81.4-1.5-1.2-1.4-0.5
Conditioned locomotion0.20.31.10.0-0.00.10.1-0.6-0.60.6-0.60.60.7-0.70.30.1-0.3-0.40.50.11.0
Cocaine response after cond. corrected2.32.84.21.21.31.7-1.4-1.8-1.91.9-1.91.91.9-1.91.2-0.5-1.91.02.11.72.0
Cocaine response after cond. not corrected2.22.65.31.01.11.5-1.2-1.6-1.81.8-1.71.71.7-1.70.70.1-2.01.02.31.92.3
Cocaine response before conditioning0.70.81.5-0.9-0.9-1.00.91.11.1-1.11.0-1.0-1.11.1-1.21.10.6-0.5-0.5-0.4-0.3
Saline control response0.50.72.5-1.3-1.0-0.81.00.70.6-0.60.5-0.5-0.60.6-1.11.60.2-0.80.1-0.20.9
Bone: connectivity density0.91.52.7-0.7-0.9-1.31.11.21.2-1.21.4-1.4-1.21.2-0.60.11.6-1.0-1.6-1.5-1.5
Bone: cortical apparent density0.30.41.90.30.3-0.2-0.20.30.7-0.70.6-0.6-0.50.50.4-0.80.50.2-0.8-0.4-1.4
Bone: cortical area2.84.26.2-1.9-1.6-2.11.92.32.5-2.52.1-2.1-2.42.4-1.61.02.2-1.3-2.4-1.9-2.2
Bone: cortical porosity0.10.10.30.50.30.4-0.3-0.4-0.50.5-0.40.40.4-0.40.2-0.4-0.40.50.30.40.1
Bone: cortical porosity0.00.00.1-0.0-0.2-0.10.10.0-0.20.2-0.00.00.0-0.0-0.00.00.1-0.1-0.0-0.10.1
Bone: cortical thickness1.22.05.3-0.8-0.6-1.20.81.41.8-1.81.4-1.4-1.61.6-0.4-0.31.8-0.7-2.1-1.5-2.3
Bone: cortical thickness0.20.30.90.60.80.4-0.8-0.30.1-0.1-0.40.40.1-0.11.0-0.9-0.20.7-0.00.2-0.7
Bone: cortical tissue density0.20.31.50.40.4-0.1-0.30.20.6-0.60.5-0.5-0.40.40.4-0.80.30.3-0.7-0.3-1.2
Condit. Reinf. active minus inactive responses0.60.71.0-0.6-0.7-0.90.90.90.9-0.91.0-1.0-0.90.9-0.90.70.7-0.6-0.7-0.8-0.6
Condit. Reinf. active-inactive response ratio0.50.61.21.01.10.9-0.9-0.8-0.60.6-0.60.60.7-0.70.8-0.9-0.70.90.50.70.1
Condit. Reinf. active responses3.24.05.4-1.8-2.0-2.22.22.22.1-2.12.3-2.3-2.22.2-2.11.61.8-1.6-1.8-1.8-1.3
Condit. Reinf. inactive responses4.04.96.3-2.1-2.2-2.42.32.52.4-2.42.5-2.5-2.52.5-2.41.71.9-1.5-2.1-1.8-1.6
Incentive salience index mean4.45.47.3-2.4-2.5-2.62.72.52.3-2.32.5-2.5-2.42.4-2.62.32.1-2.2-1.9-2.1-0.9
Condit. Reinf. lever presses9.613.419.0-4.1-4.3-4.24.43.93.5-3.53.8-3.8-3.53.5-4.24.03.2-3.8-2.7-3.1-0.8
Condit. Reinf. active minus inactive responses0.70.91.3-0.9-0.8-1.00.81.01.0-1.01.0-1.0-1.01.0-0.50.41.2-0.9-1.1-1.1-0.9
Condit. Reinf. active-inactive response ratio0.20.30.9-0.2-0.1-0.40.10.50.4-0.40.5-0.5-0.50.50.3-0.40.8-0.3-0.9-0.8-1.0
Condit. Reinf. active responses2.12.93.7-1.8-1.8-1.91.81.91.8-1.81.8-1.8-1.81.8-1.61.41.8-1.6-1.6-1.7-1.0
Condit. Reinf. inactive responses2.83.64.5-1.9-2.0-2.12.02.12.1-2.12.1-2.1-2.02.0-2.01.51.8-1.5-1.8-1.6-1.3
Condit. Reinf. lever presses3.24.45.9-1.8-1.8-2.11.92.32.3-2.32.4-2.4-2.32.3-1.81.02.2-1.5-2.3-2.1-2.1
Condit. Reinf. lever reinforcers received2.53.54.5-2.0-2.0-2.12.02.11.9-1.92.0-2.0-2.02.0-1.81.51.8-1.7-1.7-1.8-1.1
Conditioned reinforcement - actives0.10.10.4-0.1-0.6-0.10.2-0.0-0.60.6-0.20.20.1-0.10.2-0.10.2-0.6-0.2-0.50.2
Conditioned reinforcement - inactives0.40.61.00.60.20.4-0.5-0.9-1.01.0-1.01.01.0-1.00.8-0.5-0.60.20.70.50.7
Conditioned locomotion0.20.31.1-0.3-0.7-0.0-0.1-0.3-0.50.5-0.30.30.5-0.51.0-0.20.5-1.0-0.1-0.70.5
Patch foraging indifference point 0 sec0.40.83.5-0.9-1.2-0.71.1-0.3-0.50.5-0.40.40.7-0.7-0.81.10.2-1.60.4-0.31.9
Patch foraging indifference point AUC7.410.714.3-3.8-3.8-3.73.73.62.9-2.93.4-3.4-3.43.4-3.23.33.1-3.3-2.7-3.2-1.1
Delay disc. indifference point, 0s delay1.31.42.20.90.91.1-0.9-1.2-1.51.5-1.31.31.3-1.30.7-0.3-1.30.91.51.31.3
Delay disc. indifference point, 16s delay1.81.93.50.80.91.1-0.9-1.7-1.61.6-1.61.61.9-1.90.9-0.3-1.40.51.71.31.8
Delay disc. indifference point, 2s delay0.10.10.4-0.1-0.1-0.30.20.10.2-0.20.4-0.4-0.00.0-0.2-0.10.4-0.1-0.5-0.3-0.6
Delay disc. indifference point, 24s delay0.10.10.30.40.50.2-0.2-0.3-0.30.3-0.30.30.3-0.3-0.1-0.2-0.50.60.30.50.1
Delay disc. indifference point, 4s delay0.20.20.50.20.30.7-0.3-0.5-0.50.5-0.30.30.7-0.70.1-0.0-0.30.10.40.30.3
Delay disc. indifference point, 8s delay0.10.10.6-0.1-0.2-0.20.5-0.00.0-0.00.1-0.10.1-0.1-0.80.4-0.0-0.2-0.00.0-0.0
Indifference point function ln k2.34.15.32.22.22.1-2.1-2.3-1.91.9-2.22.22.2-2.21.7-1.8-2.01.91.82.01.1
Indifference point function log k2.34.15.32.22.22.1-2.1-2.3-1.91.9-2.22.22.2-2.21.7-1.8-2.01.91.82.01.1
Patch foraging total patch changes 0 sec0.50.93.5-1.2-1.5-1.01.40.2-0.00.00.0-0.00.2-0.2-1.01.30.6-1.90.0-0.71.5
Patch foraging total patch changes 12 sec2.22.84.3-1.8-1.9-1.91.91.81.4-1.41.6-1.6-1.61.6-1.31.12.0-2.0-1.8-2.1-0.8
Patch foraging total patch changes 18 sec0.60.91.9-1.3-1.4-1.11.21.00.6-0.60.9-0.9-0.90.9-1.11.20.8-1.1-0.6-0.8-0.0
Patch foraging total patch changes 24 sec1.73.05.6-2.1-2.2-2.02.11.81.2-1.21.6-1.6-1.61.6-1.61.71.8-2.4-1.4-2.0-0.2
Patch foraging total patch changes 6 sec2.23.37.0-2.2-2.6-2.22.61.61.1-1.11.4-1.4-1.21.2-2.12.11.7-2.6-1.2-1.80.5
Patch foraging time to switch 0 sec1.93.96.32.42.42.3-2.4-2.0-1.61.6-1.91.91.8-1.81.9-2.2-1.92.51.42.00.0
Patch foraging water rate 0 sec1.12.36.4-1.9-1.9-1.71.81.31.2-1.21.2-1.2-1.01.0-1.11.31.8-2.5-1.2-1.90.2
Patch foraging water rate 12 sec0.00.10.4-0.2-0.00.20.0-0.2-0.10.1-0.20.20.3-0.3-0.10.2-0.1-0.40.3-0.00.6
Patch foraging water rate 18 sec0.50.71.9-0.4-0.4-0.70.40.70.9-0.90.6-0.6-0.80.80.2-0.41.4-1.0-1.3-1.4-1.1
Patch foraging water rate 24 sec0.30.41.60.40.2-0.1-0.40.10.4-0.40.3-0.3-0.30.31.2-1.10.8-0.0-0.9-0.7-1.3
Patch foraging water rate 6 sec0.40.61.2-1.0-0.7-0.70.60.91.1-1.10.7-0.7-1.01.0-0.30.80.7-0.8-0.5-0.6-0.1
Seeking ratio, delayed vs. immediate footshock3.54.35.9-1.8-2.3-1.82.42.12.1-2.12.0-2.0-2.02.0-2.11.22.4-2.3-2.2-2.4-1.3
Distance traveled before self-admin2.33.06.4-2.4-2.5-1.51.71.81.9-1.91.5-1.5-1.61.6-1.62.41.2-2.1-0.8-1.20.3
Distance traveled after self-admin1.11.33.0-1.0-1.1-1.00.81.21.7-1.71.4-1.4-1.21.2-0.70.81.0-0.6-1.0-0.8-1.1
Extensor digitorum longus weight4.517.924.8-4.8-5.0-5.04.94.44.3-4.34.2-4.2-4.24.2-4.23.94.1-4.4-3.7-3.9-1.6
Bone: elastic displacement4.85.510.02.82.82.7-2.9-2.4-2.22.2-2.32.32.2-2.23.2-3.1-1.62.31.21.6-0.1
Bone: elastic work1.82.49.42.02.21.5-2.1-1.2-0.70.7-0.90.90.8-0.82.5-3.1-0.21.7-0.40.3-1.9
Bone: endosteal estimation1.02.34.7-2.1-1.8-1.61.81.71.2-1.21.4-1.4-1.61.6-1.92.21.0-1.4-0.7-0.90.2
Bone: endosteal perimeter0.92.04.3-2.0-1.8-1.61.81.51.2-1.21.2-1.2-1.31.3-1.82.11.0-1.5-0.6-1.00.4
Epididymis fat weight0.41.52.1-1.1-1.1-1.31.31.41.4-1.41.4-1.4-1.41.4-1.41.01.0-0.7-1.1-1.0-0.9
Delta time in closed arm before/after self-admin0.90.92.0-0.4-0.5-0.40.51.11.3-1.31.0-1.0-1.31.3-0.6-0.01.0-0.2-1.2-0.8-1.4
Delta time in open arm before/after self-admin0.60.61.30.40.30.30.0-0.9-1.11.1-0.90.91.1-1.1-0.40.1-0.90.20.90.61.0
Diff in mean of infusions in LGA sessions0.10.10.80.50.40.1-0.30.10.1-0.10.1-0.1-0.30.30.3-0.4-0.20.9-0.00.4-0.6
Delay discount exponential model param0.70.71.7-0.5-0.6-0.80.41.11.1-1.10.9-0.9-1.31.3-0.20.10.9-0.3-0.9-0.8-1.0
Extinction: sum of active levers before priming3.84.26.42.01.81.8-1.5-2.4-2.22.2-2.32.32.5-2.51.0-1.1-2.41.92.22.21.6
Active lever presses in extinction session 60.30.30.70.60.40.5-0.5-0.6-0.80.8-0.70.70.6-0.60.8-0.6-0.40.30.40.30.4
Bone: final force1.62.64.0-1.9-1.4-1.71.61.91.9-1.91.6-1.6-1.91.9-2.01.71.1-0.8-1.2-0.9-0.9
Bone: final moment1.42.23.4-1.6-1.2-1.51.41.81.8-1.81.6-1.6-1.81.8-1.81.41.0-0.6-1.2-0.8-1.1
Food consumed during 24 hour testing period0.60.81.8-1.1-0.9-1.01.10.91.0-1.00.8-0.8-0.80.8-1.31.30.4-0.7-0.3-0.40.2
Glucose2.64.05.7-2.3-2.4-2.32.32.12.0-2.02.0-2.0-2.02.0-2.11.91.9-2.0-1.7-1.8-0.7
Heart weight0.71.13.3-1.2-1.1-1.11.41.11.1-1.11.1-1.1-1.01.0-1.81.30.6-0.7-0.7-0.5-0.4
Delay discount hyperbolic model param0.50.51.3-0.4-0.4-0.60.30.90.9-0.90.8-0.8-1.11.1-0.1-0.00.7-0.1-0.8-0.6-0.8
Intermittent access intake day 1-15 change0.61.21.9-0.9-1.0-0.90.81.21.4-1.41.2-1.2-1.31.3-0.50.31.3-0.8-1.3-1.2-1.1
Intermittent access intake escalation0.51.11.9-0.7-0.8-0.70.61.11.4-1.41.2-1.2-1.31.3-0.40.21.2-0.7-1.2-1.1-1.2
Intermittent access intake escalation 21.71.93.9-0.7-0.7-0.90.81.51.8-1.81.5-1.5-1.71.7-0.4-0.21.7-0.8-1.9-1.5-2.0
Intermitt. access day 1 inactive lever presses0.31.32.7-1.4-1.4-1.61.41.11.4-1.41.0-1.0-1.01.0-1.11.31.0-1.1-0.7-0.8-0.1
Intermitt. access day 15 inactive lever presses0.00.10.4-0.2-0.40.10.40.10.4-0.4-0.10.1-0.20.2-0.60.4-0.1-0.40.2-0.00.4
Intermitt. access escalation Index0.30.51.2-1.0-1.1-0.90.60.70.8-0.80.6-0.6-0.60.6-0.81.00.4-0.5-0.10.00.3
Intermittent access day 1 total infusions1.62.55.41.20.81.4-1.1-1.8-2.32.3-2.02.01.9-1.91.4-1.0-1.30.41.50.91.8
Intermittent access day 15 total infusions0.10.10.5-0.0-0.4-0.10.10.1-0.10.10.0-0.0-0.20.20.4-0.50.7-0.5-0.6-0.7-0.3
Intermittent access terminal intake (last 3 days)0.10.10.5-0.1-0.4-0.30.20.2-0.10.1-0.00.0-0.30.30.5-0.40.7-0.6-0.5-0.7-0.1
Intermittent access total infusions0.10.20.6-0.1-0.5-0.20.2-0.1-0.60.6-0.30.30.1-0.10.5-0.20.5-0.7-0.2-0.60.4
Intermittent access day 1 locomotion1.72.14.41.00.81.1-1.0-1.8-2.12.1-1.81.82.0-2.01.7-1.0-0.90.31.10.71.3
Intermittent access day 15 total locomotion0.91.63.31.10.71.2-1.1-1.3-1.81.8-1.61.61.3-1.31.7-1.2-0.70.20.90.41.0
Intermittent access total locomotion1.41.74.01.41.01.3-1.3-1.5-1.71.7-1.41.41.4-1.42.0-1.7-0.50.60.50.30.3
Intermittent access standard deviation0.10.30.9-0.5-0.7-0.40.70.40.6-0.60.3-0.3-0.30.3-0.50.20.7-0.9-0.6-0.7-0.1
Left kidney weight0.42.06.0-2.1-2.0-1.51.81.31.2-1.20.9-0.9-1.11.1-2.02.50.5-1.2-0.2-0.40.8
Right kidney weight0.41.73.0-1.7-1.6-1.61.61.41.4-1.41.3-1.3-1.21.2-1.51.70.7-0.8-0.8-0.5-0.4
Cocaine induced anxiety0.10.20.40.40.60.5-0.6-0.4-0.30.3-0.30.30.4-0.40.6-0.3-0.50.60.50.50.2
Post-drug Anxiety0.40.41.8-1.0-0.7-0.70.70.60.5-0.50.6-0.6-0.50.5-1.21.3-0.0-0.30.10.10.5
Baseline Anxiety0.80.92.3-0.9-1.0-1.11.21.01.0-1.01.0-1.0-0.90.9-1.51.20.6-0.5-0.6-0.4-0.4
Tail length1.76.69.8-3.1-2.9-2.92.82.92.8-2.82.6-2.6-2.92.9-2.63.01.9-2.1-1.7-1.8-0.7
Length with tail1.25.211.1-3.2-3.0-2.62.82.31.9-1.91.9-1.9-2.12.1-2.73.31.5-2.4-1.0-1.50.6
Length without tail0.10.42.3-0.6-0.6-0.10.5-0.1-0.40.4-0.40.40.4-0.4-0.61.1-0.3-0.80.70.11.5
Times rat made contact with spout0.50.51.1-0.6-0.5-0.70.40.70.9-0.90.7-0.7-0.80.8-0.1-0.10.9-0.6-1.1-0.9-1.0
Lifetime Intake0.20.30.8-0.1-0.60.10.1-0.3-0.90.9-0.60.60.4-0.40.6-0.00.1-0.80.2-0.30.9
Liver weight, left0.10.10.6-0.00.10.0-0.0-0.2-0.20.2-0.30.30.2-0.2-0.40.5-0.70.50.60.80.5
Liver weight, right0.71.21.81.31.21.3-1.2-1.2-1.01.0-1.21.21.1-1.11.1-1.2-1.01.10.70.80.1
Locomotor activity0.00.00.1-0.0-0.1-0.30.10.00.1-0.1-0.00.00.0-0.0-0.10.2-0.10.10.10.10.1
Locomotor testing distance0.30.61.70.30.20.3-0.3-0.7-0.80.8-0.90.90.8-0.80.10.4-1.00.41.21.01.3
Locomotor testing rearing0.30.72.1-1.1-1.1-1.01.00.90.7-0.70.6-0.6-0.80.8-1.11.50.4-0.5-0.1-0.20.4
Locomotion in novel chamber0.30.31.30.70.70.6-0.7-0.5-0.30.3-0.20.20.5-0.50.9-1.20.20.5-0.4-0.0-0.9
Locomotion in novel chamber post-restriction1.62.65.0-1.1-1.0-1.11.02.01.8-1.81.9-1.9-2.22.2-1.00.41.7-0.5-1.9-1.5-2.1
Fecal boli incidents, locomotor time 10.40.61.51.21.00.8-0.6-0.9-0.90.9-0.60.60.9-0.90.5-1.1-0.50.90.30.5-0.3
Change in fecal boli incidents, locomotor task0.50.51.1-1.0-1.1-0.80.40.70.5-0.50.5-0.5-0.70.70.10.80.6-1.0-0.2-0.60.5
Time >=10cm from walls, locomotor time 10.20.21.2-0.5-0.3-0.10.1-0.3-0.30.3-0.40.40.4-0.4-0.10.6-0.2-0.40.60.31.1
Bouts of movement, locomotor time 11.61.82.81.71.51.5-1.4-1.5-1.31.3-1.21.21.5-1.51.1-1.2-1.31.31.11.20.5
Total resting periods, locomotor time 11.82.03.71.91.81.7-1.6-1.5-1.41.4-1.31.31.4-1.41.3-1.6-1.31.61.01.20.1
Rest time, locomotor task time 10.91.13.41.71.71.0-1.4-0.5-0.30.3-0.10.10.1-0.11.3-1.8-0.31.7-0.20.3-1.6
Distance moved, locomotor task time 10.91.43.7-1.8-1.8-1.31.40.90.7-0.70.6-0.6-0.60.6-1.11.90.7-1.9-0.1-0.71.2
Vertical activity count, locomotor time 10.40.94.3-1.3-1.4-0.60.90.50.1-0.10.0-0.0-0.20.2-1.02.1-0.3-1.20.80.22.0
Time >=10cm from walls, locomotor time 20.10.21.3-0.3-0.5-0.10.60.30.2-0.20.1-0.1-0.30.3-1.10.6-0.2-0.20.20.10.4
Bouts of movement, locomotor time 20.30.51.2-0.8-1.0-0.81.10.40.6-0.60.7-0.7-0.10.1-1.00.80.5-0.9-0.6-0.7-0.2
Total resting periods, locomotor time 20.10.20.5-0.4-0.6-0.50.70.10.3-0.30.4-0.40.1-0.1-0.60.40.3-0.6-0.4-0.5-0.2
Rest time, locomotor task time 20.70.92.41.11.31.0-1.4-0.8-0.90.9-0.70.70.6-0.61.5-1.2-0.61.00.50.5-0.1
Distance moved, locomotor task time 20.60.71.3-0.6-0.6-0.50.81.01.1-1.11.0-1.0-1.11.1-1.10.70.6-0.3-0.7-0.6-0.8
Vertical activity count, locomotor time 20.40.61.9-0.8-0.8-0.30.70.90.8-0.80.7-0.7-1.01.0-1.31.4-0.0-0.50.0-0.00.4
Light reinforcement 10.71.88.3-1.7-1.5-0.91.30.20.4-0.4-0.30.30.2-0.2-1.72.9-0.9-0.91.51.02.7
Light reinforcement 21.01.59.0-1.1-1.1-0.40.6-0.1-0.80.8-0.70.70.4-0.4-0.92.3-1.2-0.41.81.23.0
Bone: marrow area1.22.54.4-2.1-1.8-1.71.81.81.4-1.41.6-1.6-1.81.8-1.92.11.2-1.4-0.9-1.1-0.1
Bone: maximum diameter2.64.96.3-2.4-2.2-2.42.32.52.4-2.42.3-2.3-2.52.5-2.21.72.1-1.6-2.2-1.9-1.6
Bone: maximum force3.25.67.4-2.6-2.2-2.62.52.72.7-2.72.5-2.5-2.72.7-2.62.22.0-1.5-2.0-1.7-1.5
Bone: maximum moment2.74.76.4-2.3-1.9-2.42.22.52.5-2.52.3-2.3-2.52.5-2.31.81.8-1.3-1.9-1.6-1.6
Mean time between licks in bursts0.30.72.50.60.70.8-0.8-0.6-0.60.6-0.70.70.5-0.5-0.00.0-1.51.41.11.60.5
Mean num. licks in bursts1.62.53.11.71.71.7-1.7-1.7-1.81.8-1.61.61.7-1.71.6-1.4-1.61.41.41.30.7
Cd content in liver0.70.71.6-1.3-0.8-1.00.81.10.9-0.90.8-0.8-1.11.1-0.71.20.5-0.6-0.3-0.30.1
Co content in liver0.91.02.10.50.70.9-0.8-0.9-1.01.0-1.31.31.0-1.00.40.1-1.30.81.41.41.4
Cu content in liver1.61.93.31.61.81.7-1.7-1.3-1.11.1-1.31.31.1-1.11.2-1.1-1.51.81.41.50.5
Fe content in liver1.62.04.00.71.01.3-1.1-1.3-1.31.3-1.71.71.3-1.30.80.1-2.01.22.01.81.8
K content in liver0.40.41.00.30.40.6-0.5-0.6-0.70.7-0.70.70.7-0.70.30.1-0.80.30.90.81.0
Mg content in liver0.70.71.31.00.71.0-0.9-0.9-1.11.1-0.90.90.9-0.90.6-0.8-0.60.40.60.50.5
Mn content in liver1.41.62.2-1.0-1.0-1.21.01.41.4-1.41.5-1.5-1.51.5-1.00.51.4-0.7-1.5-1.2-1.4
Na content in liver1.81.94.01.31.61.6-1.6-1.2-1.01.0-1.41.41.0-1.00.8-0.6-1.92.01.62.00.7
Rb content in liver6.17.19.62.52.93.1-3.1-2.8-2.62.6-3.03.02.6-2.62.5-2.0-2.72.62.62.81.5
Se content in liver2.93.45.2-1.5-1.8-2.11.92.01.9-1.92.3-2.3-2.02.0-1.81.41.6-1.3-1.7-1.7-1.4
Sr content in liver0.80.72.0-0.7-1.3-0.91.10.80.4-0.41.0-1.0-0.60.6-1.41.00.5-0.9-0.5-0.8-0.1
Zn content in liver0.10.10.2-0.2-0.0-0.20.10.40.4-0.40.3-0.3-0.50.5-0.10.20.20.3-0.2-0.0-0.4
Bone: minimum diameter0.00.10.40.10.20.0-0.10.20.0-0.00.1-0.1-0.30.30.2-0.40.30.2-0.4-0.3-0.7
Time in familiar zone, hab. session 11.01.04.81.00.90.3-0.8-0.00.3-0.30.3-0.3-0.20.21.4-2.11.00.4-1.3-0.8-2.2
Time in novel zone, hab. session 13.43.48.60.70.81.5-1.0-1.6-1.91.9-1.91.91.8-1.8-0.10.9-2.71.32.92.62.9
Total zone transitions, hab. session 10.00.00.1-0.0-0.2-0.10.20.20.1-0.10.2-0.2-0.10.1-0.40.3-0.20.10.00.1-0.0
Total locomotion distance, hab. session 10.71.02.3-0.4-0.6-0.90.71.11.1-1.11.3-1.3-1.21.2-0.80.10.9-0.2-1.2-0.8-1.5
Locomotion velocity, hab. session 12.02.84.2-1.3-1.5-1.81.61.91.9-1.92.1-2.1-1.91.9-1.61.01.6-1.0-1.8-1.5-1.7
Time in familiar zone, hab. session 20.50.62.41.11.10.8-1.0-0.5-0.20.2-0.20.20.3-0.31.0-1.5-0.10.9-0.30.1-1.2
Time in novel zone, hab. session 22.12.14.60.80.81.3-1.0-1.5-1.61.6-1.71.71.6-1.60.70.0-1.70.82.01.62.1
Total zone transitions, hab. session 20.40.51.9-1.0-1.0-0.80.90.70.6-0.60.5-0.5-0.50.5-1.01.40.2-0.80.0-0.20.6
Total locomotion distance, hab. session 20.81.11.4-1.1-1.1-1.21.11.21.1-1.11.2-1.2-1.21.2-1.01.00.9-0.9-0.9-0.9-0.5
Locomotion velocity, hab. session 21.11.52.0-1.2-1.2-1.41.31.41.3-1.31.4-1.4-1.41.4-1.11.11.1-1.1-1.1-1.1-0.7
Novel to familiar place preference ratio4.04.46.01.71.72.2-1.8-2.3-2.42.4-2.52.52.4-2.41.4-0.9-2.41.52.42.22.2
Novelty place preference5.25.67.52.02.12.6-2.2-2.6-2.62.6-2.72.72.6-2.61.8-1.3-2.61.82.62.42.1
Time in novel zone, NPP test6.56.99.12.32.32.8-2.4-2.9-2.92.9-3.03.02.9-2.91.9-1.4-2.92.12.92.72.4
Total zone transitions, NPP test0.60.83.0-1.2-1.3-1.01.10.80.7-0.70.6-0.6-0.60.6-1.31.70.1-0.90.1-0.20.8
Total locomotion distance, NPP test1.72.33.8-1.8-1.9-1.81.91.51.3-1.31.4-1.4-1.31.3-1.72.01.2-1.8-0.8-1.30.2
Locomotion velocity, NPP test2.33.24.7-2.0-2.2-2.12.21.91.7-1.71.8-1.8-1.71.7-1.82.01.7-2.1-1.3-1.7-0.2
Intraocular pressure2.02.95.1-2.3-2.2-2.02.01.81.5-1.51.6-1.6-1.61.6-1.51.81.8-2.0-1.3-1.5-0.1
Delta distance traveled before/after self-admin0.10.10.60.50.6-0.1-0.3-0.20.2-0.20.1-0.10.1-0.10.2-0.4-0.30.80.00.4-0.5
Delta ambulatory time before/after self-admin0.50.62.11.11.10.5-0.9-0.7-0.40.4-0.40.40.5-0.50.7-0.9-0.91.50.50.9-0.3
Parametrial fat weight0.20.51.8-0.10.10.6-0.5-0.6-0.30.3-0.80.80.6-0.60.10.6-1.20.31.31.21.3
Pavlov. Cond. lever latency6.48.010.93.13.33.3-3.3-3.0-2.72.7-3.03.02.8-2.83.1-2.9-2.62.92.32.50.9
Pavlov. Cond. magazine entry latency0.60.81.1-0.9-0.9-1.00.91.00.9-0.91.0-1.0-0.90.9-1.00.90.6-0.6-0.6-0.6-0.5
Pavlov. Cond. change in total contacts2.62.73.7-1.9-1.9-1.91.91.81.6-1.61.7-1.7-1.61.6-1.71.71.5-1.8-1.3-1.5-0.4
Pavlov. Cond. index score3.34.15.3-2.1-2.3-2.32.32.22.0-2.02.3-2.3-2.12.1-2.32.01.8-1.8-1.7-1.7-1.0
Pavlov. Cond. latency score3.03.84.8-2.1-2.2-2.22.22.11.9-1.92.2-2.2-2.02.0-2.11.91.7-1.8-1.6-1.7-0.9
Pavlov. Cond. lever contacts6.17.39.5-3.0-3.1-3.13.12.92.6-2.62.9-2.9-2.72.7-2.82.62.6-2.7-2.3-2.4-1.1
Pavlov. Cond. magazine entry number0.81.01.31.01.01.1-1.0-1.1-1.11.1-1.21.21.1-1.10.9-0.8-1.00.81.00.90.8
Pavlov. Cond. intertrial magazine entries0.30.30.5-0.5-0.5-0.60.60.70.5-0.50.7-0.7-0.70.7-0.70.50.4-0.3-0.5-0.5-0.3
Pavlov. Cond. lever-magazine prob. diff.3.44.25.5-2.1-2.2-2.32.22.32.1-2.12.3-2.3-2.22.2-2.21.81.9-1.7-1.8-1.8-1.2
Pavlov. Cond. response bias3.94.96.4-2.4-2.4-2.52.52.42.3-2.32.4-2.4-2.32.3-2.42.21.9-2.0-1.7-1.8-0.9
Pavlov. Cond. lever latency3.04.05.51.71.82.1-1.9-2.2-2.22.2-2.32.32.2-2.21.9-1.2-2.01.42.11.91.9
Pavlov. Cond. magazine entry latency0.20.20.90.60.60.6-0.6-0.4-0.20.2-0.30.30.3-0.30.2-0.4-0.70.90.40.7-0.3
Pavlov. Cond. change in total contacts1.11.84.6-0.7-0.7-1.10.81.51.7-1.71.7-1.7-1.61.6-1.00.21.2-0.2-1.6-1.0-2.1
Pavlov. Cond. index score0.50.62.1-0.3-0.3-0.50.40.91.0-1.01.0-1.0-1.01.0-0.70.00.60.1-1.0-0.5-1.4
Pavlov. Cond. latency score0.70.92.7-0.4-0.4-0.70.51.01.2-1.21.2-1.2-1.11.1-0.6-0.00.9-0.1-1.2-0.8-1.7
Pavlov. Cond. lever contacts2.23.14.4-1.5-1.6-1.81.62.01.9-1.92.1-2.1-2.02.0-1.71.11.7-1.1-1.8-1.6-1.7
Pavlov. Cond. magazine entry number0.40.42.40.00.00.2-0.0-0.6-0.80.8-0.80.80.8-0.80.30.4-0.5-0.30.90.31.5
Pavlov. Cond. intertrial magazine entries0.20.30.7-0.7-0.7-0.70.60.60.4-0.40.4-0.4-0.50.5-0.20.40.8-0.8-0.6-0.8-0.1
Pavlov. Cond. lever-magazine prob. diff.0.50.72.4-0.3-0.3-0.50.30.91.1-1.11.1-1.1-1.01.0-0.6-0.00.70.1-1.0-0.5-1.6
Pavlov. Cond. response bias1.11.52.5-0.9-0.9-1.11.01.41.5-1.51.5-1.5-1.51.5-1.30.61.1-0.4-1.3-1.0-1.6
Time in closed arm before self-admin0.40.61.60.70.90.7-0.7-1.0-0.80.8-0.60.61.1-1.11.3-1.0-0.10.30.10.0-0.0
Time in closed arm after self-admin0.30.41.20.70.70.6-0.8-0.00.3-0.30.1-0.1-0.30.31.0-1.10.20.6-0.5-0.1-1.1
Time in open arm before self-admin0.91.02.6-1.4-1.4-1.21.11.20.6-0.60.7-0.7-1.21.2-1.11.60.3-0.9-0.1-0.30.6
Time in open arm after self-admin0.70.82.2-1.2-1.3-1.11.40.60.1-0.10.4-0.4-0.30.3-1.51.40.4-1.3-0.2-0.60.8
Bone: periosteal estimation1.83.85.1-2.3-1.9-2.12.02.32.1-2.12.0-2.0-2.32.3-2.01.91.7-1.4-1.6-1.5-1.0
Bone: periosteal perimeter0.50.81.6-1.3-1.1-1.11.21.00.9-0.90.7-0.7-0.90.9-1.11.20.7-0.9-0.5-0.60.0
Bone: post-yield work2.03.06.2-2.1-2.1-2.02.21.81.6-1.61.6-1.6-1.61.6-2.42.51.0-1.5-0.7-1.00.2
Progressive ratio test 1 active lever presses1.01.22.70.60.20.8-0.6-1.1-1.61.6-1.51.51.2-1.21.4-0.6-0.5-0.30.90.31.6
Progressive ratio test 1 breakpoint0.81.02.20.50.10.7-0.5-1.0-1.51.5-1.41.41.1-1.11.3-0.6-0.4-0.40.80.21.4
Progressive ratio test 1 inactive lever presses0.40.62.0-1.2-1.4-0.81.00.40.1-0.1-0.00.0-0.10.1-0.61.30.2-1.30.3-0.21.4
Progressive ratio test 2 active lever presses1.41.64.20.70.11.0-0.7-1.3-2.12.1-1.71.71.4-1.41.1-0.5-1.0-0.01.30.81.8
Progressive ratio test 2 breakpoint1.51.84.40.80.21.0-0.7-1.3-2.12.1-1.71.71.5-1.51.1-0.5-1.10.01.40.81.9
Progressive ratio test 2 inactive lever presses0.10.10.4-0.3-0.7-0.40.40.3-0.40.4-0.10.1-0.30.30.30.00.4-0.6-0.2-0.50.3
Incentive Sensitization - Responses0.50.71.40.60.00.7-0.5-0.9-1.11.1-1.11.10.9-0.90.5-0.2-0.90.21.00.81.2
Incentive Sensitization - Breakpoint0.60.81.50.60.10.8-0.6-0.9-1.21.2-1.21.21.0-1.00.6-0.2-1.00.31.00.81.2
Sum of active levers in priming session hrs 5-64.03.75.71.61.41.6-1.5-2.2-2.22.2-2.32.32.4-2.41.5-0.9-2.01.22.21.92.1
Progressive ratio0.00.00.1-0.1-0.1-0.20.3-0.2-0.20.2-0.20.20.3-0.3-0.20.2-0.20.20.20.30.2
Food seeking constrained by brief footshock5.46.613.0-3.5-3.6-3.03.32.32.0-2.02.2-2.2-1.71.7-2.93.12.3-3.6-1.7-2.30.4
Seeking ratio, punishment vs. effort1.42.13.6-1.8-1.8-1.61.51.51.2-1.21.5-1.5-1.31.3-1.31.41.5-1.9-1.1-1.5-0.2
Retroperitoneal fat weight0.31.22.61.41.51.4-1.4-1.1-0.60.6-1.11.10.9-0.90.8-1.2-1.11.60.81.3-0.1
Reaction time number correct0.10.10.4-0.4-0.4-0.40.50.1-0.10.1-0.10.10.1-0.1-0.30.50.0-0.70.1-0.20.5
Reaction time mean minus median0.61.56.3-0.2-0.3-0.90.61.11.5-1.51.3-1.3-1.31.3-0.9-0.51.20.5-1.8-0.7-2.5
Reaction time mean minus median AUC0.81.94.8-0.8-0.9-1.41.11.51.6-1.61.5-1.5-1.61.6-1.30.21.4-0.1-1.8-1.0-2.2
Reaction time num false alarms0.10.10.6-0.2-0.0-0.30.30.40.2-0.20.5-0.5-0.40.4-0.3-0.00.30.2-0.5-0.3-0.8
Reaction time num false alarms AUC0.30.50.7-0.8-0.7-0.80.80.80.6-0.60.7-0.7-0.70.7-0.70.60.7-0.4-0.7-0.6-0.5
Reaction time trials correct on left0.10.10.4-0.4-0.4-0.40.50.1-0.10.1-0.10.10.1-0.1-0.30.50.0-0.70.1-0.20.5
Reaction time trials on left0.00.10.3-0.3-0.3-0.30.4-0.0-0.10.1-0.20.20.1-0.1-0.20.4-0.1-0.50.1-0.10.5
Reaction time mean0.81.35.51.61.61.2-1.6-0.7-0.30.3-0.60.60.4-0.41.1-1.8-0.72.30.11.2-1.3
Reaction time mean AUC0.91.55.71.71.71.3-1.7-0.8-0.40.4-0.70.70.5-0.51.3-1.9-0.72.40.11.1-1.4
Median of all reaction times2.13.07.82.12.22.0-2.3-1.5-1.21.2-1.51.51.2-1.21.9-2.0-1.62.81.11.9-0.4
Reaction time omissions1.52.24.11.81.61.6-1.6-1.5-1.41.4-1.41.41.5-1.51.1-1.1-1.72.01.51.90.6
Reaction time false alarm rate0.00.10.40.10.10.00.00.20.1-0.10.3-0.3-0.20.2-0.0-0.20.20.5-0.3-0.1-0.6
Reaction time premature initiation rate2.02.76.82.42.12.0-2.1-1.8-1.21.2-1.51.51.6-1.62.2-2.6-0.71.50.50.8-0.4
Reaction time premature initiations1.11.94.32.01.71.6-1.7-1.6-1.11.1-1.41.41.5-1.51.8-2.1-0.61.00.50.7-0.1
Std. dev. reaction times0.30.63.80.60.5-0.0-0.40.40.8-0.80.5-0.5-0.60.6-0.1-0.90.31.4-0.90.2-1.9
Reaction time trials completed0.00.10.3-0.3-0.3-0.30.4-0.0-0.10.1-0.20.20.1-0.1-0.20.4-0.1-0.50.1-0.10.5
Reaction time trials AUC0.00.10.3-0.4-0.3-0.30.4-0.0-0.10.1-0.20.20.1-0.1-0.30.4-0.0-0.50.1-0.10.5
Run reversals in cocaine runway, females0.20.20.7-0.10.3-0.80.10.40.4-0.40.6-0.6-0.50.50.1-0.30.40.6-0.5-0.0-0.8
Run reversals in cocaine runway, males0.00.00.20.4-0.00.4-0.0-0.2-0.30.3-0.30.30.2-0.2-0.0-0.3-0.10.10.0-0.1-0.1
Latency to leave start box in cocaine runway0.60.71.2-0.7-0.8-0.70.70.81.1-1.10.9-0.9-0.80.8-0.30.41.0-0.8-0.9-0.9-0.7
Latency to leave start box in cocaine runway, F0.10.10.30.20.10.4-0.3-0.5-0.30.3-0.50.50.6-0.60.4-0.2-0.3-0.00.40.30.5
Latency to leave start box in cocaine runway, M1.91.82.5-1.5-1.5-1.41.31.41.6-1.61.5-1.5-1.31.3-1.11.31.3-1.4-1.2-1.2-0.6
Std. dev. time between licks in bursts0.30.40.60.60.60.6-0.6-0.6-0.70.7-0.60.60.5-0.50.4-0.4-0.80.80.60.70.2
Total sessions with >9 infusions0.40.52.1-0.1-0.50.1-0.1-0.6-0.90.9-0.80.80.8-0.80.70.3-0.4-0.60.80.21.5
Short access day 1 total inactive lever presses0.30.41.5-1.0-0.9-0.70.50.20.3-0.3-0.00.0-0.00.00.40.80.4-1.20.1-0.41.0
Short access day 10 total inactive lever presses0.41.02.2-0.9-1.0-1.00.90.91.5-1.51.0-1.0-0.90.9-0.90.61.0-0.9-0.9-0.8-0.6
Short access day 1 total infusions0.40.52.7-0.3-0.50.00.0-0.4-0.80.8-0.90.90.6-0.60.50.5-0.4-0.60.80.21.7
Short access day 10 total infusions0.50.72.7-0.1-0.30.3-0.3-0.7-1.21.2-1.01.00.9-0.90.80.2-0.6-0.41.00.51.7
Short access total infusions0.91.13.80.2-0.10.7-0.5-0.9-1.51.5-1.41.41.1-1.10.90.1-0.8-0.31.30.61.9
Short access day 1 locomotion1.92.44.11.10.81.3-1.3-1.8-1.91.9-1.91.92.0-2.01.8-0.9-1.30.61.51.21.5
Short access day 10 total locomotion0.61.01.91.21.01.1-1.0-1.3-1.11.1-0.90.91.3-1.31.4-1.4-0.50.80.30.3-0.3
Short access total locomotion0.80.92.10.50.20.5-0.7-1.2-1.31.3-1.11.11.4-1.41.3-0.4-0.70.10.90.51.1
One hour access (0.3 mA shock)0.30.31.0-0.6-1.0-0.20.50.3-0.90.9-0.10.1-0.20.2-0.20.50.3-0.90.0-0.50.8
Compulsive drug intake0.50.51.5-0.4-0.2-0.30.70.80.6-0.60.8-0.8-0.90.9-1.20.30.7-0.2-0.9-0.6-1.1
One hour access (shock baseline)0.30.52.6-0.3-0.80.20.2-0.3-1.21.2-0.80.80.4-0.40.30.4-0.2-0.90.7-0.01.6
Social response proportion1.82.14.91.91.91.7-2.0-1.2-0.90.9-1.11.11.0-1.01.4-1.3-1.72.21.21.7-0.1
Social responses0.70.91.6-0.9-1.0-1.10.91.11.3-1.31.1-1.1-1.11.1-0.91.10.6-0.5-0.6-0.5-0.5
Social time0.30.42.00.10.30.1-0.3-0.2-0.10.1-0.20.20.1-0.1-0.40.8-1.31.21.11.40.6
Soleus weight0.51.68.0-0.7-0.50.10.4-0.5-0.80.8-0.90.90.7-0.7-1.12.1-1.70.22.11.62.8
Bone: stiffness4.16.710.0-2.9-2.5-2.82.73.02.9-2.92.8-2.8-3.03.0-3.22.81.8-1.5-1.9-1.5-1.3
Tibialis anterior weight6.722.934.8-5.9-5.7-5.55.65.14.9-4.94.6-4.6-4.84.8-4.95.34.1-4.9-3.5-3.9-0.9
Time to tail flick, vehicle, before self-admin0.40.41.30.80.51.0-0.8-0.4-0.60.6-0.50.50.3-0.31.1-1.10.10.4-0.1-0.2-0.4
Time to tail flick, vehicle, after self-admin0.10.10.40.0-0.00.60.10.40.3-0.30.1-0.1-0.50.5-0.3-0.30.4-0.3-0.5-0.6-0.5
Time to tail flick, test, before self-admin0.40.40.7-0.8-0.7-0.80.80.70.3-0.30.8-0.8-0.60.6-0.50.50.8-0.7-0.7-0.8-0.4
Time to tail flick, test, after self-admin3.33.46.2-1.3-1.4-1.91.61.91.8-1.82.0-2.0-2.02.0-1.20.32.4-1.3-2.5-2.3-2.3
Delta time to tail flick, vehicle, before/after SA0.20.21.1-0.4-0.2-0.30.50.50.5-0.50.4-0.4-0.60.6-1.10.6-0.10.0-0.10.0-0.1
Delta time to tail flick, test, before/after SA0.20.21.20.30.2-0.1-0.10.20.6-0.60.3-0.3-0.30.30.2-0.70.60.0-0.7-0.6-1.1
Tibia length0.30.93.5-0.6-0.20.3-0.1-0.2-0.20.2-0.80.80.2-0.2-0.41.6-1.50.41.61.51.9
Ambulatory time before self-admin1.52.34.9-2.1-2.2-1.41.61.61.5-1.51.2-1.2-1.41.4-1.42.11.0-2.0-0.7-1.10.4
Ambulatory time after self-admin0.30.40.7-0.7-0.9-0.70.50.70.8-0.80.6-0.6-0.70.7-0.30.90.2-0.4-0.2-0.2-0.1
Bone: tissue strength0.30.31.4-0.4-0.3-0.30.30.50.6-0.60.4-0.4-0.50.5-1.20.8-0.30.40.10.5-0.2
Total heroin consumption2.22.55.01.00.91.3-1.1-1.8-1.91.9-1.91.91.9-1.90.9-0.3-1.80.62.01.62.2
Bone: trabecular number1.32.23.1-1.1-1.2-1.61.41.61.5-1.51.8-1.8-1.61.6-1.10.61.6-1.1-1.7-1.6-1.5
Bone: trabecular spacing0.00.10.30.10.20.0-0.20.10.3-0.30.0-0.0-0.20.20.3-0.40.20.2-0.3-0.1-0.5
Bone: trabecular thickness0.10.10.30.40.30.3-0.3-0.2-0.30.30.1-0.10.2-0.20.3-0.5-0.00.3-0.2-0.1-0.4
Bone: trabecular tissue density2.84.17.1-2.4-2.3-2.32.22.22.2-2.22.1-2.1-2.22.2-2.62.71.1-1.4-1.0-1.0-0.4
Water consumed over 24 hours0.71.01.6-1.0-0.8-1.00.91.01.1-1.11.0-1.0-1.01.0-0.40.31.3-1.0-1.2-1.2-0.8
Number of responses in last shaping day1.61.77.9-0.1-0.30.8-0.5-1.1-1.21.2-1.41.41.5-1.50.50.9-1.5-0.22.01.32.8