Taf6l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Taf6l 0.11 0.09 8.8e-08 0.04 0.03 0.04 0.04 2.5e-05 1.9e-04 5.0e-05 7.2e-05
2 IL gene expression Taf6l 0.14 0.09 2.8e-03 0.07 0.03 -0.01 0.03 7.6e-03 6.9e-02 9.7e-01 7.8e-02
3 Adipose gene expression Taf6l 0.11 0.06 3.4e-11 0.08 0.07 0.07 0.08 1.4e-09 1.2e-08 4.5e-08 4.3e-09
4 NAcc mRNA stability Taf6l 0.05 0.03 2.0e-07 0.03 0.05 0.05 0.05 2.4e-05 4.2e-08 5.7e-08 2.2e-08
5 Brain intron excision ratio chr1_215105885_215106353 0.03 0.02 2.6e-03 0.03 0.03 0.03 0.02 1.1e-03 8.5e-04 1.9e-03 2.3e-03
6 Brain intron excision ratio chr1_215105885_215106180 0.03 0.02 1.7e-03 0.03 0.04 0.03 0.03 4.6e-04 3.3e-04 5.4e-04 6.7e-04
7 BLA mRNA stability Taf6l 0.16 0.09 1.5e-06 0.06 0.1 0.1 0.12 3.2e-04 6.8e-06 3.6e-06 1.2e-06
8 pVTA mRNA stability Taf6l 0.09 0.05 7.9e-08 0.05 0.07 0.08 0.07 6.3e-05 1.2e-06 7.9e-07 2.0e-06
9 Brain mRNA stability Taf6l 0.04 0.03 1.1e-03 0.01 0.03 0.01 0.02 4.5e-02 1.0e-03 4.1e-02 9.1e-03
10 PL mRNA stability Taf6l 0.07 0.04 2.2e-06 0.03 0.04 0.05 0.05 1.4e-04 1.2e-05 3.0e-06 3.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.71.11.8-0.6-0.8-0.81.3-0.90.91.31.31.21.2
Area under the delay curve0.10.20.7-0.1-0.1-0.10.4-0.30.30.50.50.50.8
BMI with tail3.913.519.7-2.7-2.8-2.84.3-3.33.24.34.24.14.4
BMI without tail0.82.44.8-1.2-1.1-1.01.7-1.41.41.71.71.72.2
Body weight4.118.021.0-4.0-3.8-3.84.6-4.14.14.44.44.54.6
Weight adjusted by age0.81.21.6-1.1-1.2-1.11.3-1.11.11.11.11.11.0
Bone surface3.05.57.5-2.1-2.1-2.22.7-2.22.22.72.52.52.0
Bone volume1.52.74.4-1.3-1.4-1.42.1-1.51.42.11.81.81.4
Breakpoint value in progressive ratio session1.51.83.0-1.6-1.7-1.71.0-1.51.51.01.01.10.5
Number of licking bursts0.00.00.1-0.2-0.10.00.3-0.10.10.10.00.10.1
Context. condit. distance diff. score0.20.30.80.90.80.7-0.30.4-0.4-0.10.0-0.10.3
Locomotion velocity, session 10.10.10.30.30.10.1-0.2-0.10.1-0.00.20.20.6
Locomotion distance, session 10.70.92.0-0.4-0.5-0.60.8-0.90.91.21.21.11.4
Locomotion velocity, session 22.73.13.6-1.7-1.6-1.61.7-1.81.81.91.91.81.7
Locomotion distance, session 20.10.20.6-0.3-0.3-0.30.2-0.50.60.40.50.50.7
Locomotion velocity, session 31.01.23.2-0.4-0.4-0.31.3-0.80.81.41.31.31.8
Locomotion distance, session 30.10.10.6-0.3-0.2-0.20.2-0.30.30.20.20.30.8
Stereotopy head waving bouts, day 30.30.30.80.60.60.50.50.1-0.10.80.60.50.9
Stereotopy head waving duration, day 30.10.20.30.60.50.50.20.1-0.10.50.40.30.4
Locomotion velocity, session 70.10.10.40.20.20.20.4-0.10.10.60.50.30.4
Locomotion distance, session 70.10.10.60.30.30.40.20.0-0.00.20.30.20.8
Stereotopy head waving bouts, day 70.30.30.7-0.4-0.4-0.40.8-0.50.40.90.70.60.2
Stereotopy head waving duration, day 71.61.92.3-1.4-1.4-1.41.5-1.41.41.51.41.40.9
Locomotion velocity, session 80.10.10.50.40.40.3-0.70.2-0.1-0.5-0.3-0.3-0.0
Locomotion distance, session 80.20.30.80.90.80.80.00.4-0.40.20.30.10.5
Degree of sensitization distance0.30.30.80.20.20.20.8-0.10.10.70.80.60.9
Degree of sensitization stereotypy1.01.11.5-1.1-1.1-1.01.2-1.01.01.21.11.00.3
Conditioned locomotion0.60.70.8-0.8-0.8-0.90.7-0.90.90.70.70.80.9
Cocaine response after cond. corrected0.50.61.31.21.00.7-1.00.7-0.7-0.8-0.5-0.60.0
Cocaine response after cond. not corrected0.30.40.80.90.80.6-0.70.6-0.6-0.6-0.3-0.4-0.0
Cocaine response before conditioning0.30.40.8-0.9-0.8-0.70.7-0.50.40.60.50.4-0.2
Saline control response2.53.34.7-2.2-2.0-1.91.6-2.02.01.51.61.71.7
Bone: connectivity density2.53.95.0-1.6-1.7-1.82.2-1.91.92.22.22.12.0
Bone: cortical apparent density0.10.20.4-0.4-0.5-0.7-0.3-0.40.5-0.10.00.1-0.4
Bone: cortical area1.11.72.4-1.4-1.3-1.21.6-1.21.21.51.31.31.0
Bone: cortical porosity0.20.30.70.20.10.1-0.80.3-0.2-0.6-0.6-0.6-0.8
Bone: cortical porosity0.10.10.3-0.0-0.1-0.1-0.5-0.00.0-0.4-0.4-0.3-0.5
Bone: cortical thickness2.13.46.0-2.5-2.4-2.31.2-2.22.21.11.21.51.1
Bone: cortical thickness0.20.20.5-0.6-0.6-0.7-0.1-0.60.6-0.00.10.30.4
Bone: cortical tissue density0.20.20.7-0.6-0.7-0.8-0.2-0.60.60.00.10.2-0.3
Condit. Reinf. active minus inactive responses1.11.21.5-1.0-1.2-1.21.0-1.21.11.01.11.10.9
Condit. Reinf. active-inactive response ratio0.30.30.7-0.5-0.8-0.80.2-0.70.70.20.40.50.2
Condit. Reinf. active responses1.21.52.2-1.0-1.2-1.11.4-1.21.11.51.41.31.0
Condit. Reinf. inactive responses0.20.30.8-0.1-0.00.10.9-0.10.00.90.80.50.4
Incentive salience index mean1.72.12.5-1.3-1.4-1.31.5-1.41.41.51.61.51.4
Condit. Reinf. lever presses1.42.03.0-1.3-1.2-1.11.7-1.31.21.61.71.51.5
Condit. Reinf. active minus inactive responses0.10.20.60.30.30.3-0.10.4-0.5-0.0-0.3-0.4-0.8
Condit. Reinf. active-inactive response ratio0.30.30.80.70.70.70.20.6-0.70.3-0.0-0.3-0.9
Condit. Reinf. active responses0.00.10.2-0.4-0.3-0.30.2-0.20.20.30.10.2-0.0
Condit. Reinf. inactive responses0.10.20.3-0.6-0.5-0.6-0.2-0.40.4-0.2-0.10.20.5
Condit. Reinf. lever presses1.21.62.3-1.4-1.2-1.31.5-1.21.11.41.21.30.9
Condit. Reinf. lever reinforcers received0.10.20.4-0.6-0.5-0.60.4-0.40.40.50.30.30.0
Conditioned reinforcement - actives0.10.30.60.70.40.6-0.20.5-0.6-0.1-0.2-0.4-0.7
Conditioned reinforcement - inactives0.10.20.50.40.10.20.60.1-0.20.70.60.40.2
Conditioned locomotion1.41.84.42.11.71.7-0.81.5-1.6-0.6-0.7-0.9-0.8
Patch foraging indifference point 0 sec0.50.91.1-0.9-0.9-0.90.8-1.01.01.00.91.01.0
Patch foraging indifference point AUC1.01.42.3-1.4-1.4-1.51.1-1.31.21.21.01.00.1
Delay disc. indifference point, 0s delay0.20.20.50.70.70.7-0.10.4-0.40.00.0-0.00.6
Delay disc. indifference point, 16s delay0.30.30.5-0.3-0.3-0.30.7-0.40.40.70.70.60.6
Delay disc. indifference point, 2s delay0.10.10.30.50.60.50.10.4-0.40.30.10.00.2
Delay disc. indifference point, 24s delay0.10.10.5-0.3-0.3-0.30.3-0.40.40.20.30.40.7
Delay disc. indifference point, 4s delay0.50.51.8-0.4-0.4-0.40.5-0.70.70.70.70.81.4
Delay disc. indifference point, 8s delay0.30.40.50.70.60.7-0.70.6-0.5-0.6-0.6-0.5-0.1
Indifference point function ln k2.23.86.32.52.42.2-2.02.1-2.0-1.9-1.6-1.6-0.3
Indifference point function log k2.23.86.32.52.42.2-2.02.1-2.0-1.9-1.6-1.6-0.3
Patch foraging total patch changes 0 sec0.40.70.9-0.9-0.9-0.90.6-0.91.00.80.70.81.0
Patch foraging total patch changes 12 sec5.26.78.8-3.0-2.9-3.02.3-2.92.82.52.32.41.7
Patch foraging total patch changes 18 sec0.40.61.1-0.9-0.9-1.00.6-0.80.80.80.40.60.2
Patch foraging total patch changes 24 sec5.08.510.0-3.0-3.0-3.22.8-3.13.12.82.82.92.6
Patch foraging total patch changes 6 sec1.32.02.3-1.4-1.4-1.51.3-1.51.51.51.31.41.5
Patch foraging time to switch 0 sec0.51.02.3-0.6-0.7-0.51.4-0.80.71.51.31.10.9
Patch foraging water rate 0 sec0.51.01.70.90.80.7-1.30.9-0.9-1.3-1.2-1.0-0.7
Patch foraging water rate 12 sec1.53.15.01.71.71.7-1.91.8-1.7-2.2-1.9-1.7-0.9
Patch foraging water rate 18 sec0.30.51.00.70.80.8-0.80.7-0.6-1.0-0.6-0.50.5
Patch foraging water rate 24 sec1.42.02.61.51.51.4-1.61.4-1.3-1.6-1.3-1.4-0.9
Patch foraging water rate 6 sec1.52.23.51.41.51.5-1.71.5-1.4-1.9-1.6-1.5-0.7
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.3-0.4-0.20.3-0.20.20.40.30.30.6
Distance traveled before self-admin2.53.24.2-1.8-1.8-1.82.0-1.81.72.01.91.81.3
Distance traveled after self-admin0.30.30.8-0.7-0.9-0.90.5-0.70.60.30.30.40.1
Extensor digitorum longus weight6.726.229.2-5.4-5.4-5.25.1-5.35.34.74.95.14.6
Bone: elastic displacement0.70.81.50.70.70.6-1.20.7-0.7-1.2-1.2-1.0-0.6
Bone: elastic work0.70.91.3-1.0-1.0-1.10.5-1.11.10.50.60.81.1
Bone: endosteal estimation0.40.91.91.31.41.30.61.0-1.10.60.3-0.00.5
Bone: endosteal perimeter0.61.33.01.71.71.70.51.4-1.50.40.1-0.4-0.1
Epididymis fat weight0.20.82.01.11.41.30.41.2-1.30.1-0.1-0.4-0.2
Delta time in closed arm before/after self-admin1.00.92.4-0.8-0.8-0.80.6-1.11.10.60.91.01.5
Delta time in open arm before/after self-admin2.02.02.7-1.4-1.5-1.51.5-1.41.41.71.51.40.6
Diff in mean of infusions in LGA sessions1.82.23.0-1.6-1.7-1.71.1-1.71.71.21.31.31.1
Delay discount exponential model param0.20.20.70.10.10.1-0.40.3-0.3-0.5-0.5-0.5-0.8
Extinction: sum of active levers before priming3.94.34.8-2.1-2.2-2.22.0-2.22.22.02.12.11.8
Active lever presses in extinction session 62.72.73.4-1.7-1.8-1.81.6-1.71.71.71.71.60.9
Bone: final force2.23.44.4-1.7-1.7-1.62.1-1.81.82.12.02.01.7
Bone: final moment2.23.54.4-1.8-1.8-1.72.1-1.81.82.12.02.01.7
Food consumed during 24 hour testing period0.10.10.3-0.00.10.2-0.00.4-0.4-0.3-0.5-0.4-0.4
Glucose1.42.24.01.92.01.9-0.81.8-1.8-0.9-1.1-1.1-0.4
Heart weight0.20.31.50.50.60.50.40.3-0.20.20.30.31.2
Delay discount hyperbolic model param0.10.10.60.00.00.0-0.30.2-0.2-0.5-0.4-0.4-0.7
Intermittent access intake day 1-15 change1.12.33.71.41.51.4-1.21.6-1.7-1.3-1.4-1.6-1.9
Intermittent access intake escalation1.42.94.61.61.71.6-1.41.8-1.8-1.4-1.6-1.8-2.1
Intermittent access intake escalation 20.60.71.60.70.80.8-0.50.9-0.9-0.5-0.7-0.8-1.3
Intermitt. access day 1 inactive lever presses0.41.72.41.31.21.4-1.31.3-1.3-1.0-1.2-1.3-1.6
Intermitt. access day 15 inactive lever presses0.81.53.2-0.8-0.9-0.81.8-1.00.91.71.61.41.1
Intermitt. access escalation Index0.70.91.20.91.00.9-1.11.0-0.9-1.1-1.1-1.0-0.7
Intermittent access day 1 total infusions0.50.81.60.90.60.81.10.3-0.31.31.00.81.2
Intermittent access day 15 total infusions1.82.75.32.32.12.2-0.72.0-2.1-0.6-0.9-1.2-1.1
Intermittent access terminal intake (last 3 days)0.50.71.61.31.11.10.60.8-1.00.70.40.10.1
Intermittent access total infusions0.60.71.91.41.11.20.50.8-0.90.60.40.10.3
Intermittent access day 1 locomotion0.50.61.50.50.20.31.0-0.10.01.21.10.91.2
Intermittent access day 15 total locomotion0.20.40.90.70.40.40.80.2-0.31.00.90.50.4
Intermittent access total locomotion0.91.02.80.80.40.51.50.0-0.21.71.51.11.0
Intermittent access standard deviation0.51.01.51.21.11.1-0.71.1-1.2-0.7-0.8-0.9-1.0
Left kidney weight0.10.20.50.60.60.60.70.4-0.50.40.40.20.4
Right kidney weight0.00.10.40.30.40.40.70.3-0.30.30.20.20.3
Cocaine induced anxiety0.00.00.1-0.1-0.1-0.1-0.0-0.10.10.10.0-0.0-0.4
Post-drug Anxiety0.30.30.4-0.6-0.6-0.60.5-0.60.60.50.50.50.2
Baseline Anxiety0.40.40.8-0.6-0.6-0.60.5-0.70.70.30.50.70.9
Tail length0.20.72.0-1.4-1.1-1.00.3-0.91.00.10.10.50.5
Length with tail1.15.08.2-2.9-2.6-2.51.9-2.42.41.61.82.01.9
Length without tail2.78.810.9-3.3-3.3-3.22.7-3.13.22.42.62.82.8
Times rat made contact with spout0.10.10.2-0.4-0.3-0.3-0.3-0.20.3-0.4-0.3-0.10.2
Lifetime Intake0.50.61.61.31.01.10.40.7-0.80.50.40.10.4
Liver weight, left1.11.82.11.31.31.3-1.31.5-1.4-1.4-1.4-1.4-1.0
Liver weight, right1.01.72.61.51.61.6-1.11.5-1.5-1.1-1.2-1.1-0.0
Locomotor activity1.01.52.81.11.01.1-1.61.1-1.1-1.7-1.5-1.3-0.5
Locomotor testing distance0.81.52.51.31.21.2-1.61.2-1.1-1.5-1.4-1.2-0.2
Locomotor testing rearing0.81.62.31.21.41.3-1.51.3-1.2-1.4-1.4-1.3-0.4
Locomotion in novel chamber1.31.62.91.71.51.6-0.71.5-1.6-0.8-0.9-1.1-0.9
Locomotion in novel chamber post-restriction1.62.73.51.91.81.7-1.31.8-1.8-1.3-1.5-1.6-1.7
Fecal boli incidents, locomotor time 10.10.20.80.40.40.4-0.10.5-0.6-0.1-0.3-0.4-0.9
Change in fecal boli incidents, locomotor task1.01.01.51.21.21.2-1.11.0-1.0-1.1-0.9-0.9-0.2
Time >=10cm from walls, locomotor time 11.11.22.21.41.21.5-0.31.3-1.4-0.3-0.5-0.8-1.1
Bouts of movement, locomotor time 10.30.41.6-0.3-0.6-0.2-0.6-0.10.1-0.6-0.7-0.6-1.3
Total resting periods, locomotor time 10.20.21.3-0.3-0.5-0.3-0.4-0.10.1-0.4-0.5-0.5-1.1
Rest time, locomotor task time 11.92.32.71.31.51.2-1.61.6-1.6-1.5-1.6-1.6-1.6
Distance moved, locomotor task time 10.40.60.9-0.6-0.6-0.60.9-0.70.70.90.90.91.0
Vertical activity count, locomotor time 10.20.40.70.80.70.8-0.50.7-0.7-0.5-0.5-0.5-0.3
Time >=10cm from walls, locomotor time 20.10.10.90.1-0.00.1-0.10.3-0.3-0.1-0.2-0.4-0.9
Bouts of movement, locomotor time 20.71.11.7-1.3-1.3-1.30.9-1.21.20.80.90.90.6
Total resting periods, locomotor time 20.30.50.8-0.9-0.8-0.90.6-0.80.80.50.60.60.3
Rest time, locomotor task time 22.83.64.32.02.12.0-1.82.0-2.0-1.7-1.8-1.8-1.6
Distance moved, locomotor task time 20.30.40.8-0.8-0.9-0.90.2-0.70.70.30.30.40.1
Vertical activity count, locomotor time 20.20.20.60.10.00.1-0.80.2-0.1-0.8-0.7-0.5-0.3
Light reinforcement 10.10.20.40.10.10.1-0.40.3-0.3-0.5-0.6-0.5-0.6
Light reinforcement 20.10.20.50.10.30.30.70.3-0.40.50.20.0-0.6
Bone: marrow area0.51.02.41.51.51.50.51.2-1.30.40.1-0.20.4
Bone: maximum diameter0.40.71.7-0.5-0.5-0.51.3-0.50.51.21.10.90.5
Bone: maximum force3.86.710.0-2.3-2.2-2.23.2-2.42.33.12.92.82.5
Bone: maximum moment3.86.69.6-2.3-2.2-2.23.1-2.42.33.02.82.72.5
Mean time between licks in bursts0.20.41.8-0.6-0.7-0.60.2-0.60.7-0.10.30.51.3
Mean num. licks in bursts0.10.20.60.30.30.1-0.80.3-0.2-0.6-0.6-0.5-0.3
Cd content in liver0.70.71.31.10.90.9-0.70.9-1.0-0.4-0.6-0.8-1.1
Co content in liver1.72.03.91.11.01.0-2.01.1-1.1-1.9-1.6-1.5-1.2
Cu content in liver0.10.10.20.20.10.1-0.50.2-0.1-0.5-0.4-0.3-0.3
Fe content in liver0.00.00.10.30.20.1-0.10.1-0.1-0.00.0-0.00.0
K content in liver0.70.71.3-0.9-0.6-0.51.0-0.70.70.80.90.91.1
Mg content in liver0.20.21.1-0.1-0.0-0.00.5-0.20.30.40.50.51.0
Mn content in liver3.33.74.5-2.1-2.1-2.02.0-2.02.01.91.81.91.4
Na content in liver0.50.60.9-0.8-0.6-0.71.0-0.70.70.80.80.80.7
Rb content in liver2.52.93.91.71.92.0-1.61.8-1.8-1.7-1.7-1.7-0.8
Se content in liver0.20.20.7-0.4-0.3-0.30.8-0.30.30.70.50.50.1
Sr content in liver3.73.24.2-2.0-2.0-2.01.5-2.02.01.51.61.71.1
Zn content in liver2.83.13.6-1.6-1.8-1.81.6-1.91.91.71.81.81.6
Bone: minimum diameter0.30.50.90.80.80.91.00.6-0.70.80.50.30.7
Time in familiar zone, hab. session 10.20.20.5-0.2-0.4-0.40.5-0.30.30.40.50.50.7
Time in novel zone, hab. session 11.61.62.11.21.31.3-1.41.3-1.2-1.4-1.4-1.3-1.0
Total zone transitions, hab. session 10.10.20.3-0.5-0.4-0.40.3-0.50.50.30.40.40.2
Total locomotion distance, hab. session 10.10.10.30.40.40.30.40.1-0.10.50.50.20.2
Locomotion velocity, hab. session 10.20.30.6-0.3-0.2-0.20.7-0.50.40.80.80.60.4
Time in familiar zone, hab. session 20.60.61.60.30.30.3-1.00.7-0.6-1.3-1.2-0.9-0.3
Time in novel zone, hab. session 20.90.91.7-0.6-0.6-0.61.1-0.90.81.31.31.10.8
Total zone transitions, hab. session 21.62.03.4-1.2-1.2-1.21.3-1.41.41.51.51.51.9
Total locomotion distance, hab. session 20.40.51.4-0.3-0.2-0.20.7-0.50.50.90.80.81.2
Locomotion velocity, hab. session 20.30.41.0-0.1-0.1-0.00.7-0.40.40.90.80.71.0
Novel to familiar place preference ratio2.12.32.8-1.6-1.5-1.41.7-1.61.61.71.61.60.9
Novelty place preference1.31.41.9-1.3-1.2-1.11.4-1.21.21.31.21.20.7
Time in novel zone, NPP test1.41.51.9-1.3-1.2-1.11.4-1.31.31.41.31.30.8
Total zone transitions, NPP test1.01.41.8-1.1-1.1-1.10.9-1.31.31.21.31.31.2
Total locomotion distance, NPP test0.10.20.60.0-0.00.00.2-0.30.40.60.60.50.8
Locomotion velocity, NPP test0.00.10.20.10.10.10.0-0.20.20.40.40.30.4
Intraocular pressure0.30.41.20.30.30.3-0.70.5-0.5-0.7-0.9-0.7-1.1
Delta distance traveled before/after self-admin0.80.91.80.80.60.6-1.20.8-0.7-1.4-1.2-1.0-0.5
Delta ambulatory time before/after self-admin1.11.42.61.00.90.9-1.51.0-1.0-1.6-1.5-1.3-0.8
Parametrial fat weight0.71.63.21.71.81.7-0.11.6-1.7-0.2-0.4-0.8-0.5
Pavlov. Cond. lever latency1.41.82.61.21.11.1-1.61.2-1.2-1.5-1.5-1.4-1.4
Pavlov. Cond. magazine entry latency1.62.13.5-1.3-1.3-1.31.9-1.31.21.71.71.51.2
Pavlov. Cond. change in total contacts0.60.71.5-0.7-0.7-0.71.2-0.60.61.21.00.80.4
Pavlov. Cond. index score0.91.21.8-1.1-1.0-1.11.3-1.00.91.21.21.10.8
Pavlov. Cond. latency score0.91.11.7-1.0-0.9-1.01.3-0.90.91.21.21.11.0
Pavlov. Cond. lever contacts0.91.01.7-0.8-0.8-0.81.3-0.80.81.21.21.11.2
Pavlov. Cond. magazine entry number0.81.01.41.11.11.2-1.11.0-1.0-1.0-1.0-0.9-0.4
Pavlov. Cond. intertrial magazine entries0.10.10.6-0.1-0.2-0.1-0.3-0.00.0-0.0-0.2-0.2-0.7
Pavlov. Cond. lever-magazine prob. diff.1.01.32.0-1.1-1.1-1.11.4-1.01.01.31.21.10.8
Pavlov. Cond. response bias1.21.52.2-1.3-1.2-1.21.5-1.11.11.31.31.20.8
Pavlov. Cond. lever latency0.71.01.51.01.01.1-1.20.9-0.9-1.1-1.0-1.0-0.8
Pavlov. Cond. magazine entry latency4.95.97.5-2.7-2.7-2.72.3-2.62.62.32.32.31.7
Pavlov. Cond. change in total contacts1.52.43.2-1.6-1.6-1.81.8-1.51.41.71.51.50.8
Pavlov. Cond. index score3.04.14.9-2.1-2.1-2.22.2-2.01.92.12.02.01.3
Pavlov. Cond. latency score2.93.84.8-2.0-2.0-2.12.2-1.91.82.12.01.91.3
Pavlov. Cond. lever contacts0.50.81.1-0.9-0.9-1.01.0-0.80.80.90.80.80.6
Pavlov. Cond. magazine entry number7.59.211.83.33.33.4-2.93.2-3.2-2.9-2.9-2.9-2.0
Pavlov. Cond. intertrial magazine entries1.72.53.01.61.71.5-1.51.6-1.6-1.5-1.5-1.6-1.7
Pavlov. Cond. lever-magazine prob. diff.3.44.55.7-2.2-2.2-2.42.3-2.12.12.22.12.11.4
Pavlov. Cond. response bias2.33.13.9-1.9-1.9-2.01.9-1.71.71.71.71.71.4
Time in closed arm before self-admin0.00.00.1-0.00.10.10.40.2-0.20.30.10.0-0.1
Time in closed arm after self-admin0.70.81.00.81.01.0-0.81.0-1.0-0.9-0.9-0.8-0.3
Time in open arm before self-admin1.21.32.51.21.11.1-1.61.0-0.8-1.6-1.2-1.1-0.2
Time in open arm after self-admin0.30.30.6-0.4-0.7-0.70.2-0.70.80.30.50.50.4
Bone: periosteal estimation0.40.82.3-0.1-0.0-0.01.5-0.20.11.41.10.91.0
Bone: periosteal perimeter0.20.41.3-0.1-0.1-0.11.1-0.10.11.00.80.60.5
Bone: post-yield work0.71.03.00.20.1-0.01.7-0.20.11.71.41.11.0
Progressive ratio test 1 active lever presses0.20.31.01.00.60.8-0.10.5-0.6-0.00.0-0.2-0.2
Progressive ratio test 1 breakpoint0.20.30.91.00.60.8-0.10.5-0.6-0.00.0-0.2-0.2
Progressive ratio test 1 inactive lever presses0.71.11.8-0.7-0.9-0.71.2-0.90.91.21.31.11.1
Progressive ratio test 2 active lever presses0.40.51.61.30.91.00.00.8-0.90.10.0-0.3-0.4
Progressive ratio test 2 breakpoint0.40.51.41.20.90.90.10.8-0.90.20.1-0.2-0.3
Progressive ratio test 2 inactive lever presses0.20.30.90.90.70.80.40.6-0.70.50.3-0.0-0.1
Incentive Sensitization - Responses1.01.42.6-0.7-0.8-0.91.6-0.90.91.61.51.31.1
Incentive Sensitization - Breakpoint0.91.22.3-0.6-0.7-0.81.5-0.80.71.51.41.21.0
Sum of active levers in priming session hrs 5-60.60.61.1-1.0-1.1-1.10.5-0.80.70.60.50.3-0.8
Progressive ratio0.20.31.1-0.1-0.3-0.01.1-0.10.10.80.60.60.7
Food seeking constrained by brief footshock0.00.00.10.20.10.3-0.10.2-0.2-0.1-0.1-0.10.1
Seeking ratio, punishment vs. effort0.10.20.70.20.40.2-0.80.1-0.1-0.6-0.4-0.3-0.0
Retroperitoneal fat weight2.611.117.93.94.24.2-2.43.9-3.9-2.5-2.6-2.9-1.9
Reaction time number correct0.20.51.0-1.0-0.9-0.90.5-0.70.80.10.30.50.6
Reaction time mean minus median0.20.40.9-0.8-0.8-0.90.5-0.60.50.40.40.3-0.6
Reaction time mean minus median AUC0.10.20.9-0.4-0.4-0.5-0.3-0.10.1-0.4-0.3-0.3-1.0
Reaction time num false alarms0.50.72.00.90.70.5-1.40.6-0.5-1.2-1.0-0.8-0.2
Reaction time num false alarms AUC0.20.31.30.30.1-0.1-1.10.10.0-0.9-0.7-0.40.1
Reaction time trials correct on left0.20.51.0-1.0-0.9-0.90.5-0.70.80.10.30.50.6
Reaction time trials on left0.30.51.0-1.0-0.9-0.90.5-0.70.80.10.30.50.6
Reaction time mean0.10.10.90.20.1-0.1-0.30.2-0.3-0.2-0.2-0.4-1.0
Reaction time mean AUC0.10.21.10.30.20.1-0.40.4-0.4-0.3-0.3-0.5-1.0
Median of all reaction times0.00.00.30.20.1-0.1-0.20.1-0.20.0-0.0-0.2-0.6
Reaction time omissions0.10.20.6-0.6-0.6-0.8-0.2-0.50.5-0.10.00.1-0.4
Reaction time false alarm rate0.40.51.40.90.70.5-1.20.5-0.4-0.8-0.7-0.6-0.2
Reaction time premature initiation rate4.56.38.7-2.6-2.4-2.52.4-2.62.62.02.42.63.0
Reaction time premature initiations3.96.99.2-3.0-2.8-2.92.3-2.82.91.82.22.62.8
Std. dev. reaction times0.20.42.10.30.1-0.1-0.70.4-0.4-0.7-0.6-0.7-1.5
Reaction time trials completed0.30.51.0-1.0-0.9-0.90.5-0.70.80.10.30.50.6
Reaction time trials AUC0.20.40.8-0.9-0.8-0.80.4-0.70.70.10.30.50.6
Run reversals in cocaine runway, females1.01.03.2-0.5-0.5-0.51.0-0.80.81.01.11.11.8
Run reversals in cocaine runway, males0.70.70.90.70.70.8-0.90.8-0.8-0.9-0.9-0.9-0.8
Latency to leave start box in cocaine runway0.20.20.50.60.70.60.10.5-0.50.0-0.0-0.10.1
Latency to leave start box in cocaine runway, F0.10.10.2-0.2-0.2-0.20.4-0.20.20.40.40.40.4
Latency to leave start box in cocaine runway, M1.51.42.31.51.51.5-0.81.4-1.4-0.8-0.9-1.0-0.6
Std. dev. time between licks in bursts0.10.20.60.20.20.3-0.50.3-0.2-0.8-0.5-0.30.4
Total sessions with >9 infusions0.50.61.41.21.01.0-0.30.9-0.9-0.3-0.4-0.5-0.2
Short access day 1 total inactive lever presses0.10.20.50.50.10.10.4-0.00.00.50.60.40.7
Short access day 10 total inactive lever presses0.30.81.00.90.80.8-1.00.9-0.9-0.9-0.9-0.9-0.8
Short access day 1 total infusions0.71.02.11.51.41.3-0.51.1-1.2-0.4-0.5-0.7-0.2
Short access day 10 total infusions0.30.40.80.70.50.60.80.2-0.30.90.80.60.9
Short access total infusions0.30.41.21.10.91.00.20.6-0.60.30.30.10.6
Short access day 1 locomotion0.10.20.60.80.60.60.10.4-0.40.30.2-0.00.2
Short access day 10 total locomotion0.40.71.60.1-0.1-0.11.2-0.40.31.31.21.01.0
Short access total locomotion0.20.30.60.60.30.40.70.1-0.20.80.70.50.6
One hour access (0.3 mA shock)0.50.61.81.31.21.10.10.9-1.00.2-0.0-0.2-0.1
Compulsive drug intake0.40.51.3-1.1-0.9-1.10.0-0.80.9-0.1-0.00.20.5
One hour access (shock baseline)1.62.55.12.32.12.2-0.61.8-1.9-0.4-0.7-1.0-1.1
Social response proportion0.00.00.2-0.5-0.1-0.10.2-0.10.10.00.10.10.2
Social responses0.10.10.3-0.4-0.2-0.2-0.4-0.00.1-0.5-0.5-0.3-0.2
Social time0.20.20.6-0.00.20.1-0.60.2-0.2-0.8-0.7-0.6-0.5
Soleus weight2.78.010.03.13.03.2-2.73.1-3.0-2.5-2.6-2.8-2.2
Bone: stiffness0.91.52.8-1.2-1.2-1.01.7-1.11.01.51.41.20.8
Tibialis anterior weight8.328.334.5-5.9-5.9-5.84.9-5.85.84.84.95.24.0
Time to tail flick, vehicle, before self-admin0.60.61.4-0.3-0.3-0.41.0-0.50.51.21.00.90.9
Time to tail flick, vehicle, after self-admin0.50.61.5-0.5-0.5-0.50.9-0.70.70.90.90.91.2
Time to tail flick, test, before self-admin1.01.13.3-0.3-0.5-0.51.2-0.80.81.21.21.31.8
Time to tail flick, test, after self-admin0.00.00.1-0.3-0.2-0.20.3-0.10.10.20.20.1-0.2
Delta time to tail flick, vehicle, before/after SA0.20.20.3-0.5-0.4-0.30.3-0.50.50.20.30.40.5
Delta time to tail flick, test, before/after SA0.50.52.5-0.2-0.1-0.1-0.70.3-0.3-0.7-0.7-0.8-1.6
Tibia length1.54.26.0-2.1-2.1-2.02.3-2.02.02.52.22.00.9
Ambulatory time before self-admin1.72.63.4-1.6-1.6-1.61.9-1.61.51.81.71.61.0
Ambulatory time after self-admin0.20.20.3-0.4-0.6-0.50.6-0.40.40.40.30.40.2
Bone: tissue strength0.30.30.60.30.50.6-0.40.6-0.6-0.8-0.7-0.6-0.4
Total heroin consumption4.24.97.4-2.7-2.7-2.71.6-2.62.61.71.81.91.2
Bone: trabecular number1.72.83.9-1.3-1.4-1.42.0-1.51.52.01.81.81.7
Bone: trabecular spacing1.01.32.40.70.90.9-1.51.0-1.0-1.5-1.4-1.3-1.0
Bone: trabecular thickness0.10.10.20.40.30.30.00.3-0.40.0-0.1-0.2-0.3
Bone: trabecular tissue density6.29.110.33.03.02.9-3.23.0-3.0-3.0-2.9-3.1-3.1
Water consumed over 24 hours0.40.51.1-1.1-0.9-0.90.5-0.80.80.10.30.50.6
Number of responses in last shaping day0.10.10.2-0.3-0.3-0.30.1-0.40.40.30.30.30.5