Hub : Genes

Taf6l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Taf6l 0.11 0.08 1.8e-09 0.06 0.05 0.06 0.05 7.3e-07 5.3e-06 8.2e-07 3.5e-06
2 pVTA intron excision ratio chr1_205681773_205682180 0.08 0.06 7.4e-03 0.02 0.04 0.02 0.02 6.6e-02 6.4e-03 5.3e-02 5.6e-02
3 Brain gene expression Taf6l 0.08 0.05 6.6e-08 0.08 0.07 0.07 0.07 6.0e-08 2.2e-07 3.2e-07 1.9e-07
4 Adipose gene expression Taf6l 0.12 0.06 1.3e-13 0.09 0.09 0.08 0.1 2.3e-10 2.5e-10 4.0e-09 9.1e-11
5 PL gene expression Taf6l 0.04 0.03 1.0e-05 0.04 0.04 0.05 0.04 1.9e-05 1.1e-05 7.0e-06 2.8e-05
6 NAcc mRNA stability Taf6l 0.08 0.05 9.0e-09 0.07 0.08 0.08 0.07 1.8e-08 3.5e-09 1.5e-09 1.4e-08
7 Brain mRNA stability Taf6l 0.09 0.05 5.2e-08 0.08 0.08 0.04 0.06 9.9e-08 1.1e-07 5.0e-05 2.0e-06
8 BLA mRNA stability Taf6l 0.14 0.08 6.4e-07 0.06 0.09 0.09 0.09 5.2e-04 1.4e-05 1.4e-05 1.0e-05
9 Brain intron excision ratio chr1_205676766_205677061 0.03 0.02 1.1e-03 0.03 0.03 0.02 0.03 8.9e-04 1.6e-03 3.8e-03 1.7e-03
10 Brain intron excision ratio chr1_205676766_205677234 0.03 0.02 1.9e-03 0.02 0.02 0.01 0.02 2.5e-03 3.2e-03 2.1e-02 6.2e-03
11 RMTg gene expression Taf6l 0.16 0.1 1.6e-03 0.04 0.03 0.06 0.04 2.4e-02 7.2e-02 8.8e-03 2.8e-02
12 IL gene expression Taf6l 0.21 0.11 1.1e-04 0.16 0.08 0.08 0.12 1.5e-04 5.2e-03 6.3e-03 7.3e-04
13 PL mRNA stability Taf6l 0.11 0.06 1.4e-10 0.06 0.1 0.09 0.1 1.8e-07 5.7e-11 2.0e-10 6.2e-11
14 pVTA mRNA stability Taf6l 0.23 0.11 1.9e-05 0.12 0.09 0.09 0.1 5.8e-06 9.4e-05 1.4e-04 3.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.50.81.80.6-1.00.5-0.60.4-1.3-0.81.0-0.60.61.40.61.0-1.3
Area under the delay curve0.10.10.4-0.0-0.00.0-0.0-0.10.20.00.3-0.30.30.60.30.7-0.6
BMI with tail2.99.318.62.7-3.12.8-2.72.0-2.6-2.53.6-2.62.64.32.43.9-4.0
BMI without tail1.02.14.21.4-1.21.5-1.41.3-0.9-1.11.6-1.51.51.51.52.0-1.5
Body weight3.414.418.04.1-3.74.2-4.13.8-2.8-3.84.0-4.04.03.34.04.2-2.7
Weight adjusted by age1.72.03.81.5-1.71.5-1.51.3-2.0-1.51.5-0.90.91.31.01.2-1.2
Bone surface2.23.97.81.9-2.51.8-1.91.4-2.8-2.02.3-1.41.42.41.41.8-2.1
Bone volume1.22.05.21.2-1.91.1-1.20.7-2.3-1.31.7-0.70.72.10.71.2-1.9
Breakpoint value in progressive ratio session1.51.72.91.5-1.51.5-1.61.7-1.5-1.51.2-1.31.3-0.11.10.50.1
Number of licking bursts0.00.00.00.10.00.1-0.0-0.00.10.1-0.1-0.20.20.2-0.10.0-0.1
Context. condit. distance diff. score0.30.30.9-1.00.7-0.90.9-0.70.00.8-0.30.1-0.1-0.0-0.10.2-0.4
Locomotion velocity, session 10.10.10.4-0.30.4-0.20.20.10.40.10.1-0.40.4-0.20.50.6-0.0
Locomotion distance, session 10.60.82.10.6-0.50.5-0.60.6-0.5-0.61.1-1.21.20.71.21.4-0.8
Locomotion velocity, session 22.42.94.11.8-1.71.8-1.81.7-1.3-1.62.0-1.91.91.21.81.7-1.1
Locomotion distance, session 20.20.30.90.4-0.10.3-0.40.50.3-0.30.5-0.90.9-0.10.90.7-0.1
Locomotion velocity, session 30.70.92.40.5-0.60.5-0.40.3-1.0-0.41.1-0.80.81.60.71.5-1.5
Locomotion distance, session 30.10.10.20.30.10.3-0.20.3-0.1-0.20.2-0.30.30.20.50.50.1
Stereotopy head waving bouts, day 30.40.52.7-0.6-0.1-0.50.5-0.6-0.30.50.5-0.30.31.20.20.7-1.7
Stereotopy head waving duration, day 30.20.30.8-0.70.2-0.60.6-0.50.40.50.2-0.30.30.50.20.4-0.9
Locomotion velocity, session 70.10.10.6-0.2-0.1-0.30.3-0.3-0.60.20.3-0.10.10.50.10.2-0.8
Locomotion distance, session 70.10.20.3-0.50.5-0.50.5-0.40.40.4-0.1-0.20.20.20.10.5-0.5
Stereotopy head waving bouts, day 70.30.31.00.2-0.80.3-0.20.2-0.9-0.20.8-0.40.40.80.40.2-1.0
Stereotopy head waving duration, day 71.82.23.11.5-1.81.6-1.61.5-1.4-1.51.7-1.31.31.31.51.3-1.1
Locomotion velocity, session 80.30.31.0-0.50.8-0.40.40.01.00.3-0.3-0.40.4-1.00.40.10.7
Locomotion distance, session 80.20.30.9-0.80.4-0.80.7-0.7-0.10.70.0-0.00.00.50.00.3-0.9
Degree of sensitization distance0.40.42.6-0.4-0.1-0.40.4-0.6-0.00.30.3-0.10.11.2-0.10.7-1.6
Degree of sensitization stereotypy0.91.02.11.0-1.41.1-1.00.9-1.4-0.91.3-0.70.71.00.80.6-0.9
Conditioned locomotion0.50.61.10.7-0.70.8-0.70.9-0.6-0.80.8-0.90.90.31.00.8-0.2
Cocaine response after cond. corrected0.70.82.5-1.21.3-1.21.1-0.91.61.0-0.80.3-0.3-0.7-0.3-0.10.4
Cocaine response after cond. not corrected0.50.61.1-1.01.0-1.00.9-0.91.10.8-0.60.6-0.6-0.4-0.6-0.10.2
Cocaine response before conditioning0.40.52.30.9-1.00.8-0.80.4-1.5-0.70.60.5-0.50.7-0.3-0.0-0.3
Saline control response2.12.74.41.9-1.32.0-1.92.0-1.1-1.81.5-1.91.90.62.11.7-0.1
Bone: connectivity density1.82.94.41.6-1.91.6-1.61.3-2.1-1.72.1-1.41.41.91.32.0-1.7
Bone: cortical apparent density0.40.51.10.7-0.50.7-0.71.0-0.3-0.80.5-1.01.0-0.61.00.20.7
Bone: cortical area1.11.64.71.3-1.51.3-1.31.0-2.2-1.21.3-0.90.91.41.10.9-1.1
Bone: cortical porosity0.20.20.8-0.30.3-0.30.3-0.00.50.2-0.4-0.10.1-0.90.0-0.70.7
Bone: cortical porosity0.20.20.9-0.00.10.0-0.10.40.5-0.2-0.2-0.40.4-0.90.4-0.40.7
Bone: cortical thickness2.44.07.32.4-1.52.4-2.32.7-1.6-2.31.6-2.32.3-0.12.51.50.6
Bone: cortical thickness0.50.51.10.7-0.10.7-0.71.1-0.3-0.80.3-0.90.9-0.61.10.60.9
Bone: cortical tissue density0.50.71.30.7-0.50.8-0.81.1-0.2-0.90.6-1.11.1-0.61.10.30.8
Condit. Reinf. active minus inactive responses0.91.11.61.0-1.11.1-1.11.1-1.2-1.11.1-1.01.00.71.01.0-0.5
Condit. Reinf. active-inactive response ratio0.30.30.70.5-0.40.6-0.60.9-0.4-0.70.4-0.80.8-0.20.70.40.3
Condit. Reinf. active responses1.11.42.91.0-1.51.1-1.00.9-1.7-1.01.4-0.70.71.40.81.0-1.4
Condit. Reinf. inactive responses0.50.62.60.1-0.80.1-0.1-0.4-0.90.00.50.6-0.61.5-0.50.1-1.6
Incentive salience index mean1.41.72.71.3-1.41.3-1.31.2-1.6-1.31.5-1.11.11.41.21.4-1.2
Condit. Reinf. lever presses1.01.32.61.1-1.21.1-1.00.7-1.3-1.01.3-0.60.61.60.91.4-1.5
Condit. Reinf. active minus inactive responses0.30.41.1-0.50.1-0.50.5-0.7-0.60.6-0.40.8-0.8-0.0-1.0-1.00.2
Condit. Reinf. active-inactive response ratio0.80.82.0-0.8-0.2-0.80.8-1.2-0.80.8-0.21.1-1.10.7-1.4-1.0-0.9
Condit. Reinf. active responses0.00.00.40.2-0.10.2-0.10.1-0.70.0-0.00.1-0.10.1-0.0-0.20.2
Condit. Reinf. inactive responses0.20.30.80.50.40.4-0.50.70.1-0.3-0.2-0.50.5-0.60.90.50.9
Condit. Reinf. lever presses0.91.22.51.3-1.41.3-1.31.0-1.6-1.11.2-0.60.61.10.60.8-0.8
Condit. Reinf. lever reinforcers received0.10.20.90.5-0.40.5-0.40.4-0.9-0.30.3-0.20.20.10.2-0.10.2
Conditioned reinforcement - actives2.02.03.2-1.50.8-1.51.5-1.71.21.4-1.21.8-1.8-0.3-1.8-1.80.4
Conditioned reinforcement - inactives0.80.91.7-1.00.1-0.91.0-1.30.21.0-0.41.3-1.30.9-1.3-0.8-0.8
Conditioned locomotion1.61.93.6-1.80.9-1.51.7-1.90.91.5-0.91.6-1.60.6-1.6-0.9-0.7
Patch foraging indifference point 0 sec0.50.81.20.9-0.80.9-0.91.0-0.9-0.81.0-1.11.10.50.90.9-0.4
Patch foraging indifference point AUC2.02.34.51.8-2.11.8-1.81.5-1.8-1.81.8-1.21.21.01.10.7-0.6
Delay disc. indifference point, 0s delay0.30.30.7-0.60.6-0.60.6-0.70.80.5-0.10.1-0.10.6-0.00.6-0.8
Delay disc. indifference point, 16s delay0.30.31.10.4-0.60.3-0.30.1-0.8-0.30.6-0.20.21.00.10.6-1.0
Delay disc. indifference point, 2s delay0.30.30.9-0.50.2-0.50.5-0.80.40.50.00.4-0.40.9-0.50.2-0.8
Delay disc. indifference point, 24s delay0.10.10.40.20.10.3-0.30.40.0-0.20.2-0.50.5-0.10.60.70.0
Delay disc. indifference point, 4s delay0.40.51.60.3-0.10.4-0.40.40.4-0.30.6-1.01.00.51.01.3-0.6
Delay disc. indifference point, 8s delay0.30.41.0-0.71.0-0.60.7-0.41.00.7-0.70.1-0.1-0.6-0.1-0.10.4
Indifference point function ln k3.04.18.6-2.62.9-2.52.5-2.22.62.3-2.21.5-1.5-1.0-1.3-0.50.6
Indifference point function log k3.04.18.6-2.62.9-2.52.5-2.22.62.3-2.21.5-1.5-1.0-1.3-0.50.6
Patch foraging total patch changes 0 sec0.40.71.40.8-0.50.9-0.91.1-0.6-0.80.8-1.21.20.11.00.90.1
Patch foraging total patch changes 12 sec5.57.29.62.9-3.03.0-3.03.1-2.7-3.12.9-3.03.01.02.71.9-0.7
Patch foraging total patch changes 18 sec0.40.50.90.8-0.90.7-0.90.8-0.6-0.90.9-0.80.8-0.00.70.10.3
Patch foraging total patch changes 24 sec7.08.610.83.1-3.03.1-3.23.2-2.7-3.23.1-3.33.31.73.22.8-1.6
Patch foraging total patch changes 6 sec1.11.72.61.2-1.21.3-1.41.4-1.6-1.31.5-1.51.50.71.31.4-0.6
Patch foraging time to switch 0 sec0.61.02.50.7-1.30.6-0.70.3-1.2-0.91.4-0.40.41.60.50.9-1.5
Patch foraging water rate 0 sec0.50.71.5-0.81.2-0.80.8-0.50.80.9-1.20.5-0.5-1.1-0.5-0.71.1
Patch foraging water rate 12 sec1.62.56.0-1.72.4-1.51.6-1.22.01.8-2.21.0-1.0-1.5-0.8-0.81.5
Patch foraging water rate 18 sec0.60.82.8-0.91.7-1.00.9-0.71.31.0-1.30.3-0.3-0.6-0.20.30.5
Patch foraging water rate 24 sec1.21.73.4-1.41.8-1.51.4-1.21.61.3-1.70.9-0.9-1.3-0.9-0.81.1
Patch foraging water rate 6 sec1.11.74.4-1.22.1-1.31.3-1.01.61.4-1.80.8-0.8-1.5-0.6-0.61.1
Seeking ratio, delayed vs. immediate footshock0.00.00.10.2-0.00.0-0.20.00.0-0.10.2-0.20.20.20.10.3-0.3
Distance traveled before self-admin2.32.43.71.8-1.91.7-1.81.6-1.9-1.81.7-1.41.41.11.41.1-0.9
Distance traveled after self-admin0.30.30.90.7-0.70.7-0.70.7-0.9-0.70.3-0.30.30.10.30.00.0
Extensor digitorum longus weight6.224.330.55.5-4.95.5-5.45.2-4.2-5.35.2-5.35.33.55.25.0-2.8
Bone: elastic displacement0.91.02.5-0.81.3-0.80.8-0.41.50.8-1.10.5-0.5-1.6-0.3-0.81.5
Bone: elastic work0.70.92.30.9-0.30.9-0.91.2-0.0-0.90.7-1.31.3-0.41.51.00.5
Bone: endosteal estimation1.12.35.0-1.50.3-1.61.5-2.2-0.61.5-0.41.7-1.72.0-1.7-0.2-2.2
Bone: endosteal perimeter1.63.36.6-1.80.3-1.81.8-2.6-0.91.8-0.62.2-2.22.1-2.1-0.9-2.5
Epididymis fat weight0.30.81.9-0.50.4-0.60.7-1.20.31.0-0.41.1-1.11.3-1.00.1-1.4
Delta time in closed arm before/after self-admin1.51.53.71.0-0.31.0-1.01.3-0.3-1.01.0-1.81.80.21.71.9-0.4
Delta time in open arm before/after self-admin1.51.43.11.3-1.81.3-1.31.1-1.6-1.41.5-0.90.90.90.90.5-0.7
Diff in mean of infusions in LGA sessions1.41.52.81.4-1.11.4-1.41.7-0.7-1.50.9-1.51.5-0.51.40.50.5
Delay discount exponential model param0.10.10.40.0-0.0-0.00.00.1-0.2-0.1-0.30.3-0.3-0.6-0.3-0.60.6
Extinction: sum of active levers before priming3.63.65.12.0-2.12.1-2.12.1-1.9-2.31.9-2.02.01.12.01.6-0.9
Active lever presses in extinction session 62.22.23.71.7-1.91.8-1.71.8-1.8-1.81.6-1.31.30.51.30.7-0.3
Bone: final force2.33.76.31.9-2.11.9-1.91.7-2.5-1.82.2-1.61.62.01.81.9-1.7
Bone: final moment2.23.66.31.9-2.11.9-1.91.7-2.5-1.82.1-1.61.61.91.81.9-1.7
Food consumed during 24 hour testing period0.10.10.5-0.10.1-0.10.1-0.3-0.40.2-0.30.5-0.50.0-0.7-0.50.4
Glucose2.23.35.9-2.01.5-2.02.1-2.41.02.2-1.62.1-2.10.2-2.4-1.3-0.5
Heart weight0.71.01.8-1.21.3-1.21.2-1.21.31.1-1.00.8-0.8-0.0-0.9-0.1-0.3
Delay discount hyperbolic model param0.10.10.50.00.0-0.00.00.1-0.3-0.0-0.30.3-0.3-0.7-0.3-0.70.7
Intermittent access intake day 1-15 change1.61.53.8-1.00.7-1.21.0-1.10.91.0-1.21.5-1.5-1.1-1.6-2.01.1
Intermittent access intake escalation1.01.02.6-0.70.5-0.90.7-0.80.70.7-0.91.2-1.2-0.9-1.3-1.61.0
Intermittent access intake escalation 20.10.10.8-0.0-0.4-0.1-0.0-0.0-0.1-0.1-0.10.4-0.4-0.4-0.4-0.90.5
Intermitt. access day 1 inactive lever presses1.51.63.0-1.51.0-1.51.6-1.71.21.5-1.01.4-1.40.1-1.4-1.1-0.0
Intermitt. access day 15 inactive lever presses0.60.63.60.4-1.00.3-0.3-0.3-0.7-0.20.80.1-0.11.9-0.20.5-1.5
Intermitt. access escalation Index0.20.21.0-0.40.7-0.50.4-0.51.00.4-0.40.1-0.10.1-0.10.3-0.0
Intermittent access day 1 total infusions1.21.45.0-1.10.1-0.91.0-1.60.11.00.31.0-1.02.2-1.00.6-2.2
Intermittent access day 15 total infusions2.73.16.0-1.90.9-1.91.9-2.51.11.9-1.12.3-2.30.7-2.3-1.4-0.6
Intermittent access terminal intake (last 3 days)1.01.03.2-0.8-0.4-0.70.7-1.4-0.20.70.21.2-1.21.8-1.2-0.2-1.6
Intermittent access total infusions1.01.22.5-1.0-0.0-1.01.0-1.5-0.00.90.01.3-1.31.6-1.3-0.2-1.5
Intermittent access day 1 locomotion1.01.15.7-0.5-0.2-0.40.5-0.9-0.30.30.80.2-0.22.2-0.21.3-2.4
Intermittent access day 15 total locomotion0.50.62.5-0.5-0.4-0.30.4-0.8-0.40.30.50.6-0.61.6-0.60.2-1.6
Intermittent access total locomotion1.51.78.9-0.4-1.0-0.20.3-1.0-1.00.21.10.5-0.53.0-0.51.0-3.0
Intermittent access standard deviation1.51.63.0-1.30.9-1.21.2-1.20.91.2-1.21.5-1.5-1.0-1.5-1.71.0
Left kidney weight0.10.31.40.3-0.60.3-0.2-0.1-0.3-0.20.4-0.10.11.2-0.20.4-1.1
Right kidney weight0.30.82.60.7-1.20.5-0.60.2-1.2-0.60.9-0.40.41.50.10.5-1.6
Cocaine induced anxiety0.20.30.70.5-0.80.5-0.60.4-0.6-0.50.7-0.30.30.60.30.2-0.4
Post-drug Anxiety0.50.61.50.9-1.20.9-0.90.8-0.9-0.90.8-0.60.60.60.60.2-0.3
Baseline Anxiety0.90.91.61.1-0.81.1-1.11.3-0.8-1.10.8-1.21.2-0.01.20.8-0.0
Tail length0.72.14.61.8-0.81.8-1.72.1-0.3-1.50.9-1.81.8-0.71.91.00.8
Length with tail2.07.310.53.2-2.53.2-3.13.2-2.0-2.92.5-3.13.11.13.02.5-0.7
Length without tail1.94.25.52.3-2.12.3-2.32.1-1.9-2.22.1-2.22.21.62.11.9-1.2
Times rat made contact with spout0.30.30.90.30.30.3-0.40.70.3-0.3-0.1-0.70.7-0.80.70.21.0
Lifetime Intake0.91.02.2-1.00.3-1.01.0-1.50.31.0-0.11.2-1.21.3-1.2-0.0-1.4
Liver weight, left0.30.50.8-0.70.9-0.70.6-0.60.60.7-0.90.6-0.6-0.7-0.6-0.60.6
Liver weight, right0.10.10.50.10.00.0-0.1-0.1-0.4-0.00.1-0.20.20.70.20.7-0.7
Locomotor activity1.01.64.0-1.22.0-1.11.1-0.62.01.2-1.60.6-0.6-1.7-0.4-0.61.5
Locomotor testing distance1.01.74.7-1.32.2-1.31.3-0.82.01.3-1.50.6-0.6-1.7-0.3-0.31.4
Locomotor testing rearing1.01.53.4-1.21.8-1.31.2-1.11.21.4-1.41.1-1.1-1.2-0.8-0.61.1
Locomotion in novel chamber1.82.24.5-1.50.7-1.51.5-2.00.51.5-1.02.1-2.10.7-2.1-1.4-0.6
Locomotion in novel chamber post-restriction2.12.53.8-1.81.6-1.91.9-1.81.21.9-1.71.4-1.4-1.1-1.6-1.80.7
Fecal boli incidents, locomotor time 10.30.40.9-0.4-0.3-0.30.3-0.7-0.40.1-0.20.9-0.90.5-1.0-0.9-0.4
Change in fecal boli incidents, locomotor task0.80.83.5-0.91.3-0.90.9-0.81.91.1-0.90.1-0.1-0.4-0.10.10.3
Time >=10cm from walls, locomotor time 11.81.83.4-1.50.5-1.31.5-1.80.11.4-0.81.8-1.80.9-1.8-1.2-0.9
Bouts of movement, locomotor time 10.50.62.80.5-0.10.5-0.40.8-0.0-0.4-0.2-0.10.1-1.60.1-1.01.7
Total resting periods, locomotor time 10.30.41.50.6-0.30.5-0.50.7-0.3-0.40.0-0.10.1-1.10.0-0.91.2
Rest time, locomotor task time 11.41.62.1-1.31.3-1.31.2-1.11.11.4-1.41.1-1.1-1.3-1.2-1.41.1
Distance moved, locomotor task time 10.30.41.20.5-0.60.6-0.50.3-0.0-0.60.7-0.40.41.10.50.8-0.8
Vertical activity count, locomotor time 10.50.51.0-0.80.8-0.80.9-0.91.00.7-0.70.8-0.8-0.0-0.7-0.50.1
Time >=10cm from walls, locomotor time 20.20.20.8-0.3-0.2-0.10.3-0.3-0.40.1-0.30.7-0.7-0.1-0.7-0.90.2
Bouts of movement, locomotor time 21.01.11.91.4-1.01.3-1.41.3-0.7-1.31.0-1.11.10.11.20.8-0.0
Total resting periods, locomotor time 20.50.51.01.0-0.70.9-1.00.9-0.6-0.90.7-0.70.7-0.00.80.5-0.0
Rest time, locomotor task time 22.83.34.5-2.11.9-2.12.0-2.01.62.1-1.91.8-1.8-1.1-1.9-1.70.8
Distance moved, locomotor task time 20.30.40.80.8-0.60.9-0.70.9-0.3-0.80.5-0.50.5-0.20.60.20.4
Vertical activity count, locomotor time 20.40.52.2-0.10.8-0.10.20.30.90.0-0.6-0.10.1-1.50.2-0.41.5
Light reinforcement 10.10.20.9-0.10.6-0.30.2-0.20.60.3-0.60.4-0.4-0.6-0.2-0.70.9
Light reinforcement 20.40.61.5-0.0-0.6-0.30.2-0.8-0.70.30.21.0-1.01.2-0.9-0.7-1.0
Bone: marrow area1.12.55.2-1.60.5-1.71.6-2.3-0.41.7-0.51.8-1.81.9-1.7-0.3-2.2
Bone: maximum diameter0.50.93.00.5-1.20.5-0.50.1-1.7-0.51.0-0.20.21.70.30.4-1.7
Bone: maximum force3.56.010.62.3-2.92.2-2.21.6-3.3-2.22.8-1.71.73.21.82.5-3.0
Bone: maximum moment3.25.610.12.2-2.72.2-2.21.6-3.2-2.12.7-1.71.73.11.72.4-2.8
Mean time between licks in bursts0.50.72.10.80.00.9-0.91.10.6-0.80.3-1.01.0-0.11.11.40.2
Mean num. licks in bursts0.10.20.8-0.20.5-0.20.20.10.40.1-0.40.1-0.1-0.90.2-0.20.9
Cd content in liver1.01.11.9-1.40.8-1.41.2-1.30.61.1-1.01.3-1.3-0.4-1.0-1.10.2
Co content in liver2.93.47.8-1.62.4-1.61.6-0.92.21.4-2.31.2-1.2-2.8-0.9-1.62.7
Cu content in liver0.20.30.70.30.10.4-0.40.60.8-0.40.1-0.80.8-0.40.70.50.5
Fe content in liver0.00.00.1-0.2-0.2-0.10.1-0.1-0.30.00.10.0-0.00.2-0.0-0.1-0.3
K content in liver1.71.64.21.2-1.41.2-1.10.9-2.1-0.91.4-0.90.91.80.81.3-1.5
Mg content in liver1.01.02.80.6-1.00.7-0.60.4-1.7-0.41.1-0.70.71.70.51.2-1.6
Mn content in liver2.02.33.41.8-1.81.8-1.71.6-1.8-1.51.6-1.31.31.31.21.2-0.8
Na content in liver0.91.03.50.9-1.20.9-0.80.8-1.9-0.81.1-0.70.71.00.80.6-0.8
Rb content in liver1.21.42.3-1.41.5-1.41.5-1.41.41.5-1.21.2-1.2-0.3-1.0-0.60.2
Se content in liver0.50.62.40.7-1.30.6-0.60.3-1.5-0.50.8-0.10.11.2-0.10.1-1.1
Sr content in liver4.84.46.32.5-2.32.4-2.52.4-1.5-2.42.1-2.32.30.92.31.6-0.5
Zn content in liver4.14.67.12.2-2.42.2-2.22.2-2.7-2.32.4-2.22.21.52.01.8-1.3
Bone: minimum diameter0.81.55.2-0.8-0.2-0.90.8-1.5-1.21.00.01.2-1.22.2-1.00.1-2.3
Time in familiar zone, hab. session 10.20.20.50.3-0.40.3-0.30.1-0.5-0.30.40.3-0.30.70.00.6-0.6
Time in novel zone, hab. session 11.41.32.3-1.21.5-1.21.3-1.01.11.2-1.40.8-0.8-1.2-0.9-1.01.2
Total zone transitions, hab. session 10.30.41.10.5-0.40.5-0.50.7-0.1-0.40.5-1.01.00.01.10.5-0.1
Total locomotion distance, hab. session 10.20.21.2-0.4-0.2-0.40.3-0.5-0.60.40.3-0.10.10.8-0.00.1-1.1
Locomotion velocity, hab. session 10.20.30.90.2-0.70.2-0.20.2-0.8-0.20.7-0.70.70.80.50.4-0.9
Time in familiar zone, hab. session 20.70.82.5-0.41.1-0.30.4-0.31.20.4-1.11.0-1.0-1.1-0.5-0.61.6
Time in novel zone, hab. session 20.80.81.80.6-1.00.6-0.60.5-1.1-0.61.2-1.01.01.00.71.0-1.4
Total zone transitions, hab. session 21.41.83.31.4-1.11.3-1.31.3-1.1-1.31.5-1.41.41.11.51.8-0.9
Total locomotion distance, hab. session 20.20.30.80.3-0.40.2-0.30.1-0.7-0.20.7-0.50.50.90.30.9-0.9
Locomotion velocity, hab. session 20.20.31.30.2-0.40.1-0.1-0.1-0.8-0.00.7-0.40.41.00.10.7-1.1
Novel to familiar place preference ratio2.02.13.21.7-1.81.6-1.61.4-1.3-1.41.6-1.31.31.31.31.2-1.2
Novelty place preference1.21.22.11.3-1.51.3-1.31.0-0.9-1.01.3-0.90.91.10.80.8-1.1
Time in novel zone, NPP test1.31.32.11.4-1.41.3-1.31.1-1.0-1.01.3-1.01.01.11.01.0-1.1
Total zone transitions, NPP test1.01.42.51.2-1.01.1-1.21.3-0.7-1.21.4-1.51.50.41.61.4-0.4
Total locomotion distance, NPP test0.10.10.40.1-0.1-0.0-0.10.1-0.1-0.10.5-0.60.60.20.50.6-0.3
Locomotion velocity, NPP test0.10.10.3-0.00.0-0.10.10.10.00.00.4-0.50.5-0.10.40.3-0.1
Intraocular pressure0.20.30.7-0.10.3-0.20.2-0.20.80.3-0.60.5-0.5-0.7-0.6-0.90.8
Delta distance traveled before/after self-admin0.70.71.3-0.91.1-0.80.8-0.61.00.8-1.10.7-0.7-0.9-0.6-0.60.8
Delta ambulatory time before/after self-admin1.11.32.3-1.11.5-1.11.1-0.91.51.1-1.40.8-0.8-1.2-0.8-0.81.1
Parametrial fat weight1.12.24.6-1.80.8-1.61.8-2.10.61.6-1.01.7-1.71.1-1.7-0.9-1.2
Pavlov. Cond. lever latency1.51.83.4-1.21.6-1.31.2-0.91.61.4-1.60.8-0.8-1.9-0.9-1.51.7
Pavlov. Cond. magazine entry latency1.41.84.51.2-1.81.3-1.20.8-2.1-1.41.6-0.50.51.90.61.0-1.6
Pavlov. Cond. change in total contacts0.70.72.60.5-1.30.6-0.50.1-1.6-0.71.00.1-0.11.4-0.20.2-1.2
Pavlov. Cond. index score0.70.92.20.9-1.31.0-0.90.6-1.5-1.11.1-0.30.31.20.40.6-0.9
Pavlov. Cond. latency score0.60.81.90.8-1.10.9-0.80.5-1.4-1.01.1-0.30.31.20.40.8-0.9
Pavlov. Cond. lever contacts0.40.51.20.6-0.80.6-0.60.3-1.0-0.70.8-0.20.21.10.30.7-0.9
Pavlov. Cond. magazine entry number0.60.82.3-0.91.4-1.00.9-0.71.51.2-1.00.2-0.2-0.8-0.3-0.20.4
Pavlov. Cond. intertrial magazine entries0.10.10.40.2-0.30.1-0.10.2-0.1-0.00.10.1-0.1-0.4-0.2-0.60.4
Pavlov. Cond. lever-magazine prob. diff.0.91.12.51.0-1.51.1-1.00.7-1.6-1.21.2-0.40.41.30.50.7-1.0
Pavlov. Cond. response bias0.81.02.41.0-1.41.0-1.00.7-1.6-1.11.2-0.20.21.20.30.6-0.9
Pavlov. Cond. lever latency0.50.71.5-0.91.0-0.80.9-0.51.10.8-1.00.3-0.3-1.2-0.4-0.81.1
Pavlov. Cond. magazine entry latency3.43.96.02.4-2.32.4-2.52.2-2.3-2.42.3-1.61.61.11.41.6-0.7
Pavlov. Cond. change in total contacts1.52.04.81.6-2.01.6-1.71.1-2.2-1.51.6-0.50.51.60.60.8-1.1
Pavlov. Cond. index score2.43.15.42.1-2.32.0-2.11.6-2.3-2.02.0-0.90.91.71.01.4-1.3
Pavlov. Cond. latency score2.32.85.21.9-2.21.9-1.91.4-2.3-1.82.0-0.80.81.70.91.3-1.4
Pavlov. Cond. lever contacts0.30.40.80.8-0.80.8-0.90.6-0.8-0.80.6-0.00.00.60.20.4-0.3
Pavlov. Cond. magazine entry number5.97.210.5-3.23.2-3.23.2-2.93.03.1-3.12.2-2.2-1.8-2.1-2.21.3
Pavlov. Cond. intertrial magazine entries1.41.92.7-1.51.4-1.61.6-1.41.31.6-1.51.1-1.1-1.0-1.2-1.60.7
Pavlov. Cond. lever-magazine prob. diff.2.63.35.52.2-2.32.1-2.21.7-2.3-2.12.1-1.01.01.71.11.5-1.2
Pavlov. Cond. response bias1.31.83.01.7-1.71.6-1.71.4-1.6-1.61.4-0.70.71.10.81.0-0.7
Time in closed arm before self-admin0.10.10.30.1-0.5-0.1-0.0-0.3-0.50.10.10.5-0.50.6-0.5-0.4-0.4
Time in closed arm after self-admin0.50.50.9-0.71.0-0.80.7-0.80.70.9-0.80.6-0.6-0.3-0.6-0.20.2
Time in open arm before self-admin1.31.45.4-1.12.0-1.01.1-0.72.31.1-1.40.2-0.2-1.5-0.2-0.21.2
Time in open arm after self-admin0.20.21.2-0.10.20.1-0.00.50.3-0.2-0.2-0.40.4-1.10.4-0.30.9
Bone: periosteal estimation0.61.25.10.0-0.9-0.10.0-0.6-1.90.10.80.4-0.42.3-0.30.5-2.2
Bone: periosteal perimeter0.40.72.80.1-0.80.0-0.1-0.4-1.70.00.50.3-0.31.6-0.20.1-1.7
Bone: post-yield work1.52.09.0-0.4-1.1-0.50.3-1.2-2.00.20.81.0-1.02.8-1.20.4-3.0
Progressive ratio test 1 active lever presses1.81.82.9-1.71.1-1.51.6-1.61.01.5-1.11.6-1.6-0.3-1.6-1.20.1
Progressive ratio test 1 breakpoint2.02.13.2-1.81.2-1.61.7-1.71.11.6-1.21.7-1.7-0.5-1.7-1.40.3
Progressive ratio test 1 inactive lever presses0.10.10.60.1-0.10.1-0.10.0-0.2-0.10.5-0.30.30.60.20.7-0.8
Progressive ratio test 2 active lever presses1.41.53.0-1.40.5-1.31.4-1.70.51.3-0.71.6-1.60.6-1.7-1.0-0.6
Progressive ratio test 2 breakpoint2.32.64.5-1.81.0-1.81.8-2.11.01.7-1.22.0-2.00.1-2.1-1.6-0.1
Progressive ratio test 2 inactive lever presses0.80.91.8-0.8-0.1-0.80.9-1.3-0.10.80.11.1-1.11.3-1.3-0.3-1.3
Incentive Sensitization - Responses0.40.41.60.3-0.90.3-0.3-0.0-0.8-0.30.70.0-0.01.3-0.10.4-1.2
Incentive Sensitization - Breakpoint0.40.41.80.2-0.80.2-0.2-0.2-0.6-0.20.60.2-0.21.3-0.20.3-1.2
Sum of active levers in priming session hrs 5-60.90.92.51.1-1.61.1-1.11.1-1.3-1.20.9-0.50.50.10.4-0.40.2
Progressive ratio0.20.21.10.4-0.50.3-0.3-0.0-0.70.00.30.2-0.21.1-0.00.2-0.8
Food seeking constrained by brief footshock0.10.20.6-0.20.7-0.30.3-0.20.80.4-0.5-0.00.0-0.40.1-0.00.4
Seeking ratio, punishment vs. effort0.40.41.7-0.50.9-0.50.5-0.11.30.3-0.5-0.30.3-1.10.20.00.9
Retroperitoneal fat weight1.86.010.8-2.82.4-2.82.9-3.32.43.0-2.32.7-2.70.3-2.7-1.5-0.6
Reaction time number correct0.50.71.41.2-0.41.1-1.11.2-0.8-0.80.4-0.90.9-0.11.00.80.3
Reaction time mean minus median0.30.31.40.7-1.20.6-0.70.4-0.5-0.90.50.0-0.00.2-0.1-0.6-0.2
Reaction time mean minus median AUC0.20.20.70.4-0.40.3-0.40.40.0-0.5-0.10.1-0.1-0.7-0.1-0.80.7
Reaction time num false alarms0.70.92.9-0.81.4-0.70.7-0.21.70.7-1.00.1-0.1-1.6-0.1-0.21.5
Reaction time num false alarms AUC0.50.72.7-0.21.0-0.20.10.41.50.2-0.6-0.60.6-1.70.50.11.6
Reaction time trials correct on left0.50.71.41.2-0.41.1-1.11.2-0.8-0.80.4-0.90.9-0.11.00.80.3
Reaction time trials on left0.50.71.51.2-0.41.1-1.11.2-0.8-0.80.4-0.90.9-0.21.00.80.4
Reaction time mean0.10.20.8-0.2-0.3-0.30.1-0.3-0.0-0.1-0.10.7-0.7-0.3-0.7-0.90.2
Reaction time mean AUC0.20.31.0-0.3-0.2-0.40.2-0.4-0.10.0-0.20.9-0.9-0.3-0.9-1.00.2
Median of all reaction times0.10.10.2-0.1-0.4-0.1-0.0-0.1-0.3-0.30.20.3-0.30.0-0.4-0.4-0.1
Reaction time omissions0.20.31.60.00.10.0-0.20.50.7-0.5-0.2-0.20.2-1.30.2-0.51.1
Reaction time false alarm rate0.50.72.8-0.91.1-0.80.8-0.41.70.7-0.70.1-0.1-1.2-0.2-0.21.0
Reaction time premature initiation rate3.64.97.82.5-1.72.4-2.42.4-1.6-2.32.1-2.52.51.32.62.8-1.0
Reaction time premature initiations4.56.39.33.1-1.82.9-2.93.0-1.8-2.72.1-2.92.90.83.02.9-0.4
Std. dev. reaction times0.30.42.0-0.3-0.1-0.30.2-0.20.5-0.0-0.50.7-0.7-1.0-0.8-1.40.8
Reaction time trials completed0.50.71.51.2-0.41.1-1.11.2-0.8-0.80.4-0.90.9-0.21.00.80.4
Reaction time trials AUC0.40.61.21.1-0.31.0-1.01.1-0.7-0.70.3-0.80.8-0.10.90.80.3
Run reversals in cocaine runway, females1.21.24.00.8-0.40.8-0.80.8-0.6-0.71.1-1.31.31.01.52.0-1.1
Run reversals in cocaine runway, males0.60.60.9-0.80.9-0.80.8-0.60.80.8-0.90.5-0.5-0.9-0.5-0.80.7
Latency to leave start box in cocaine runway0.40.41.1-0.60.2-0.60.5-0.90.50.6-0.10.6-0.61.0-0.60.1-0.9
Latency to leave start box in cocaine runway, F0.10.10.40.0-0.30.1-0.1-0.10.0-0.00.3-0.00.00.60.00.2-0.5
Latency to leave start box in cocaine runway, M2.72.53.9-1.91.6-1.91.8-2.01.41.9-1.61.8-1.8-0.3-1.6-1.20.2
Std. dev. time between licks in bursts0.30.41.7-0.41.0-0.40.4-0.21.30.4-0.80.2-0.2-0.6-0.20.20.6
Total sessions with >9 infusions1.31.53.1-1.41.1-1.51.4-1.81.01.4-0.81.4-1.40.6-1.4-0.3-0.8
Short access day 1 total inactive lever presses0.70.81.5-1.10.7-1.01.1-1.20.51.0-0.50.9-0.90.7-0.90.0-1.0
Short access day 10 total inactive lever presses2.12.33.8-1.82.0-1.71.8-1.71.91.7-1.61.3-1.3-0.8-1.3-1.00.7
Short access day 1 total infusions0.80.81.8-0.90.8-1.11.0-1.40.81.1-0.51.0-1.00.5-1.0-0.0-0.7
Short access day 10 total infusions0.80.94.3-0.5-0.1-0.50.5-1.10.20.50.50.5-0.52.1-0.60.8-2.0
Short access total infusions0.50.61.8-0.70.4-0.80.7-1.10.50.70.10.6-0.61.2-0.70.5-1.3
Short access day 1 locomotion0.60.73.30.1-0.40.1-0.1-0.2-0.6-0.20.9-0.20.21.70.21.3-1.8
Short access day 10 total locomotion0.50.63.00.0-0.50.0-0.0-0.3-0.2-0.10.8-0.20.21.70.21.0-1.7
Short access total locomotion1.01.04.40.3-0.70.3-0.3-0.1-0.7-0.41.2-0.50.51.90.41.5-2.1
One hour access (0.3 mA shock)3.03.56.7-2.11.4-2.22.2-2.61.32.2-1.42.3-2.30.3-2.3-1.6-0.3
Compulsive drug intake1.31.32.71.20.21.0-1.11.7-0.6-0.90.3-1.41.4-1.51.40.91.1
One hour access (shock baseline)4.24.98.8-2.51.2-2.52.5-3.01.52.3-1.62.8-2.80.4-2.8-2.3-0.2
Social response proportion0.10.10.30.6-0.20.5-0.50.3-0.1-0.20.3-0.10.10.30.10.4-0.1
Social responses0.20.21.20.40.30.3-0.30.50.1-0.2-0.2-0.20.2-1.00.4-0.21.1
Social time0.20.31.30.20.6-0.1-0.00.20.70.2-0.6-0.30.3-1.20.2-0.41.1
Soleus weight2.16.39.2-2.92.8-3.02.9-2.91.72.9-2.62.7-2.7-1.4-2.4-2.21.0
Bone: stiffness1.11.84.51.3-1.81.3-1.30.8-2.1-1.21.5-0.70.71.90.71.0-1.6
Tibialis anterior weight8.729.838.26.2-5.76.1-6.16.1-4.3-6.15.7-6.16.13.05.84.9-2.3
Time to tail flick, vehicle, before self-admin1.01.03.30.6-1.20.6-0.70.2-1.0-0.71.3-0.70.71.80.51.1-1.7
Time to tail flick, vehicle, after self-admin0.50.51.50.7-0.40.6-0.60.6-0.4-0.60.7-0.90.90.71.01.2-0.7
Time to tail flick, test, before self-admin0.80.82.50.3-0.40.4-0.40.4-0.8-0.40.8-0.90.91.20.81.6-1.5
Time to tail flick, test, after self-admin0.10.10.2-0.20.3-0.40.2-0.20.00.3-0.30.2-0.2-0.5-0.3-0.40.3
Delta time to tail flick, vehicle, before/after SA0.10.10.20.00.30.0-0.00.20.1-0.0-0.1-0.20.2-0.40.40.20.4
Delta time to tail flick, test, before/after SA0.50.52.0-0.00.2-0.10.10.10.30.1-0.50.4-0.4-1.3-0.4-1.31.4
Tibia length1.64.510.42.2-3.02.3-2.11.7-3.2-2.02.6-1.51.52.31.11.2-1.9
Ambulatory time before self-admin1.92.03.91.6-2.01.6-1.61.4-1.9-1.61.6-1.01.01.11.00.7-0.8
Ambulatory time after self-admin0.30.41.20.6-0.90.6-0.60.3-1.1-0.60.5-0.00.00.90.10.2-0.6
Bone: tissue strength0.30.30.7-0.10.5-0.20.3-0.40.40.5-0.60.8-0.8-0.1-0.8-0.40.2
Total heroin consumption2.93.46.22.2-1.72.2-2.22.5-1.4-2.21.6-2.22.2-0.32.11.00.4
Bone: trabecular number1.01.63.21.0-1.51.0-1.00.7-1.6-1.21.5-0.90.91.80.81.4-1.6
Bone: trabecular spacing0.70.92.6-0.51.2-0.50.5-0.31.40.6-1.10.7-0.7-1.5-0.5-0.81.6
Bone: trabecular thickness0.20.30.5-0.6-0.1-0.60.5-0.7-0.40.3-0.30.7-0.70.4-0.7-0.6-0.5
Bone: trabecular tissue density4.36.08.9-2.72.6-2.72.7-2.43.02.6-2.62.1-2.1-2.1-2.1-2.61.6
Water consumed over 24 hours0.40.40.90.9-0.30.8-0.90.9-0.3-0.60.2-0.80.8-0.30.60.40.6
Number of responses in last shaping day0.10.10.2-0.10.4-0.20.1-0.00.40.1-0.1-0.10.1-0.40.10.30.1