Hub : Genes

Taf6l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Taf6l 0.11 0.09 8.8e-08 0.04 0.03 0.04 0.04 2.5e-05 1.9e-04 5.2e-05 6.1e-05
2 IL gene expression Taf6l 0.14 0.09 2.8e-03 0.07 0.03 -0.01 0.03 7.6e-03 6.9e-02 9.7e-01 7.6e-02
3 Adipose gene expression Taf6l 0.11 0.06 3.4e-11 0.08 0.07 0.07 0.08 1.4e-09 1.2e-08 4.5e-08 4.6e-09
4 NAcc mRNA stability Taf6l 0.05 0.03 2.0e-07 0.03 0.05 0.05 0.05 2.4e-05 4.2e-08 5.6e-08 2.2e-08
5 Brain intron excision ratio chr1_215105885_215106353 0.03 0.02 2.6e-03 0.03 0.03 0.03 0.02 1.1e-03 8.5e-04 1.9e-03 2.2e-03
6 Brain intron excision ratio chr1_215105885_215106180 0.03 0.02 1.7e-03 0.03 0.04 0.03 0.03 4.6e-04 3.3e-04 5.4e-04 6.5e-04
7 BLA mRNA stability Taf6l 0.16 0.09 1.5e-06 0.06 0.1 0.1 0.12 3.2e-04 6.8e-06 3.6e-06 1.2e-06
8 pVTA mRNA stability Taf6l 0.09 0.05 7.9e-08 0.05 0.07 0.08 0.07 6.3e-05 1.2e-06 7.9e-07 1.9e-06
9 Brain mRNA stability Taf6l 0.04 0.03 1.1e-03 0.01 0.03 0.01 0.02 4.5e-02 1.0e-03 4.1e-02 8.7e-03
10 PL mRNA stability Taf6l 0.07 0.04 2.2e-06 0.03 0.04 0.05 0.05 1.4e-04 1.2e-05 3.0e-06 3.3e-06
11 PL alternative TSS XM_008760224.4 0.03 0.02 7.9e-03 0 0.01 0.02 0.01 1.6e-01 1.0e-02 4.5e-03 4.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.61.11.80.60.80.81.3-0.90.91.3-1.31.2-1.2-0.6
Area under the delay curve0.10.20.70.10.10.10.4-0.30.30.5-0.50.5-0.80.2
BMI with tail3.512.319.72.72.82.84.3-3.33.24.3-4.24.1-4.4-1.0
BMI without tail0.42.24.81.21.11.01.7-1.41.41.7-1.71.7-2.2-0.3
Body weight3.716.421.04.03.83.84.6-4.14.14.4-4.44.5-4.6-0.7
Weight adjusted by age0.41.11.61.11.21.11.3-1.11.11.1-1.11.1-1.00.1
Bone surface2.55.07.52.12.12.22.7-2.22.22.7-2.52.5-2.0-0.6
Bone volume1.32.64.41.31.41.42.1-1.51.42.1-1.81.8-1.4-1.1
Breakpoint value in progressive ratio session1.01.83.01.61.71.71.0-1.51.51.0-1.01.1-0.51.2
Number of licking bursts0.00.00.30.20.1-0.00.3-0.10.10.1-0.00.1-0.1-0.5
Context. condit. distance diff. score0.20.20.8-0.9-0.8-0.7-0.30.4-0.4-0.1-0.0-0.1-0.30.4
Locomotion velocity, session 10.10.10.3-0.3-0.1-0.1-0.2-0.10.1-0.0-0.20.2-0.60.4
Locomotion distance, session 10.70.92.00.40.50.60.8-0.90.91.2-1.21.1-1.41.0
Locomotion velocity, session 22.42.93.61.71.61.61.7-1.81.81.9-1.91.8-1.71.0
Locomotion distance, session 20.20.30.80.30.30.30.2-0.50.60.4-0.50.5-0.70.9
Locomotion velocity, session 31.01.13.20.40.40.31.3-0.80.81.4-1.31.3-1.8-0.4
Locomotion distance, session 30.10.10.60.30.20.20.2-0.30.30.2-0.20.3-0.80.0
Stereotopy head waving bouts, day 30.30.30.8-0.6-0.6-0.50.50.1-0.10.8-0.60.5-0.9-0.1
Stereotopy head waving duration, day 30.10.10.3-0.6-0.5-0.50.20.1-0.10.5-0.40.3-0.40.2
Locomotion velocity, session 70.10.10.4-0.2-0.2-0.20.4-0.10.10.6-0.50.3-0.40.4
Locomotion distance, session 70.10.20.6-0.3-0.3-0.40.20.0-0.00.2-0.30.2-0.80.8
Stereotopy head waving bouts, day 70.30.30.70.40.40.40.8-0.50.40.9-0.70.6-0.2-0.7
Stereotopy head waving duration, day 71.41.82.31.41.41.41.5-1.41.41.5-1.41.4-0.9-0.5
Locomotion velocity, session 80.20.31.4-0.4-0.4-0.3-0.70.2-0.1-0.50.3-0.30.01.2
Locomotion distance, session 80.20.30.8-0.9-0.8-0.80.00.4-0.40.2-0.30.1-0.50.3
Degree of sensitization distance0.30.30.8-0.2-0.2-0.20.8-0.10.10.7-0.80.6-0.9-0.3
Degree of sensitization stereotypy0.91.01.51.11.11.01.2-1.01.01.2-1.11.0-0.4-0.8
Conditioned locomotion0.50.60.80.80.80.90.7-0.90.90.7-0.70.8-0.9-0.3
Cocaine response after cond. corrected0.40.61.3-1.2-1.0-0.7-1.00.7-0.7-0.80.5-0.60.00.7
Cocaine response after cond. not corrected0.20.30.8-0.9-0.8-0.6-0.70.6-0.6-0.60.3-0.40.00.3
Cocaine response before conditioning0.30.40.80.90.80.70.7-0.50.40.6-0.50.40.2-0.6
Saline control response2.23.04.72.22.01.91.6-2.02.01.5-1.61.7-1.70.4
Bone: connectivity density2.23.65.01.61.71.82.2-1.91.92.2-2.22.1-2.00.3
Bone: cortical apparent density0.30.43.30.40.50.7-0.3-0.40.5-0.1-0.00.10.41.8
Bone: cortical area1.01.62.41.41.31.21.6-1.21.21.5-1.31.3-1.0-0.6
Bone: cortical porosity0.30.31.1-0.2-0.1-0.1-0.80.3-0.2-0.60.6-0.60.91.1
Bone: cortical porosity0.20.21.00.00.10.1-0.5-0.00.0-0.40.4-0.30.51.0
Bone: cortical thickness2.03.36.02.52.42.31.2-2.22.21.1-1.21.5-1.11.3
Bone: cortical thickness0.20.20.50.60.60.7-0.1-0.60.6-0.0-0.10.3-0.40.6
Bone: cortical tissue density0.40.64.00.60.70.8-0.2-0.60.60.0-0.10.20.32.0
Condit. Reinf. active minus inactive responses1.01.11.51.01.21.21.0-1.21.11.0-1.11.1-0.90.3
Condit. Reinf. active-inactive response ratio0.30.30.70.50.80.80.2-0.70.70.2-0.40.5-0.20.7
Condit. Reinf. active responses1.11.42.21.01.21.11.4-1.21.11.5-1.41.3-1.0-0.1
Condit. Reinf. inactive responses0.30.31.10.10.0-0.10.9-0.10.00.9-0.80.5-0.4-1.0
Incentive salience index mean1.51.92.51.31.41.31.5-1.41.41.5-1.61.5-1.40.0
Condit. Reinf. lever presses1.21.83.01.31.21.11.7-1.31.21.6-1.71.5-1.5-0.3
Condit. Reinf. active minus inactive responses0.10.10.6-0.3-0.3-0.3-0.10.4-0.5-0.00.3-0.40.80.1
Condit. Reinf. active-inactive response ratio0.20.30.8-0.7-0.7-0.70.20.6-0.70.30.0-0.30.9-0.1
Condit. Reinf. active responses0.00.10.20.40.30.30.2-0.20.20.3-0.10.20.00.1
Condit. Reinf. inactive responses0.10.20.30.60.50.6-0.2-0.40.4-0.20.10.2-0.5-0.4
Condit. Reinf. lever presses1.11.52.31.41.21.31.5-1.21.11.4-1.21.3-0.9-0.9
Condit. Reinf. lever reinforcers received0.10.20.40.60.50.60.4-0.40.40.5-0.30.3-0.00.2
Conditioned reinforcement - actives0.10.30.6-0.7-0.4-0.6-0.20.5-0.6-0.10.2-0.40.7-0.6
Conditioned reinforcement - inactives0.10.31.1-0.4-0.1-0.20.60.1-0.20.7-0.60.4-0.2-1.1
Conditioned locomotion1.21.74.4-2.1-1.7-1.7-0.81.5-1.6-0.60.7-0.90.8-1.1
Patch foraging indifference point 0 sec0.30.81.10.90.90.90.8-1.01.01.0-0.91.0-1.00.7
Patch foraging indifference point AUC0.51.32.31.41.41.51.1-1.31.21.2-1.01.0-0.10.6
Delay disc. indifference point, 0s delay0.20.20.5-0.7-0.7-0.7-0.10.4-0.40.0-0.0-0.0-0.6-0.5
Delay disc. indifference point, 16s delay0.20.30.50.30.30.30.7-0.40.40.7-0.70.6-0.6-0.4
Delay disc. indifference point, 2s delay0.20.20.6-0.5-0.6-0.50.10.4-0.40.3-0.10.0-0.2-0.8
Delay disc. indifference point, 24s delay0.10.10.50.30.30.30.3-0.40.40.2-0.30.4-0.70.4
Delay disc. indifference point, 4s delay0.50.51.80.40.40.40.5-0.70.70.7-0.70.8-1.40.9
Delay disc. indifference point, 8s delay0.20.40.5-0.7-0.6-0.7-0.70.6-0.5-0.60.6-0.50.10.7
Indifference point function ln k1.23.56.3-2.5-2.4-2.2-2.02.1-2.0-1.91.6-1.60.3-0.7
Indifference point function log k1.23.56.3-2.5-2.4-2.2-2.02.1-2.0-1.91.6-1.60.3-0.7
Patch foraging total patch changes 0 sec0.30.70.90.90.90.90.6-0.91.00.8-0.70.8-1.00.9
Patch foraging total patch changes 12 sec5.06.78.83.02.93.02.3-2.92.82.5-2.32.4-1.72.5
Patch foraging total patch changes 18 sec0.30.71.40.90.91.00.6-0.80.80.8-0.40.6-0.21.2
Patch foraging total patch changes 24 sec2.37.810.03.03.03.22.8-3.13.12.8-2.82.9-2.60.9
Patch foraging total patch changes 6 sec1.11.92.31.41.41.51.3-1.51.51.5-1.31.4-1.50.9
Patch foraging time to switch 0 sec0.20.92.30.60.70.51.4-0.80.71.5-1.31.1-0.9-0.2
Patch foraging water rate 0 sec0.20.91.7-0.9-0.8-0.7-1.30.9-0.9-1.31.2-1.00.7-0.3
Patch foraging water rate 12 sec0.72.95.0-1.7-1.7-1.7-1.91.8-1.7-2.21.9-1.70.9-0.9
Patch foraging water rate 18 sec0.20.51.0-0.7-0.8-0.8-0.80.7-0.6-1.00.6-0.5-0.5-0.9
Patch foraging water rate 24 sec1.31.82.6-1.5-1.5-1.4-1.61.4-1.3-1.61.3-1.40.9-0.0
Patch foraging water rate 6 sec1.42.03.5-1.4-1.5-1.5-1.71.5-1.4-1.91.6-1.50.7-0.3
Seeking ratio, delayed vs. immediate footshock0.10.10.30.30.40.20.3-0.20.20.4-0.30.3-0.6-0.2
Distance traveled before self-admin1.32.94.21.81.81.82.0-1.81.72.0-1.91.8-1.3-0.3
Distance traveled after self-admin0.20.30.80.70.90.90.5-0.70.60.3-0.30.4-0.10.2
Extensor digitorum longus weight6.023.929.25.45.45.25.1-5.35.34.7-4.95.1-4.60.1
Bone: elastic displacement0.60.81.5-0.7-0.7-0.6-1.20.7-0.7-1.21.2-1.00.7-0.2
Bone: elastic work0.60.81.31.01.01.10.5-1.11.10.5-0.60.8-1.10.2
Bone: endosteal estimation0.61.46.8-1.3-1.4-1.30.61.0-1.10.6-0.3-0.0-0.5-2.6
Bone: endosteal perimeter0.92.210.2-1.7-1.7-1.70.51.4-1.50.4-0.1-0.40.1-3.2
Epididymis fat weight0.31.35.9-1.1-1.4-1.30.41.2-1.30.10.1-0.40.2-2.4
Delta time in closed arm before/after self-admin1.21.13.00.80.80.80.6-1.11.10.6-0.91.0-1.51.7
Delta time in open arm before/after self-admin1.61.82.71.41.51.51.5-1.41.41.7-1.51.4-0.60.2
Diff in mean of infusions in LGA sessions1.22.23.01.61.71.71.1-1.71.71.2-1.31.3-1.11.5
Delay discount exponential model param0.10.20.7-0.1-0.1-0.1-0.40.3-0.3-0.50.5-0.50.8-0.2
Extinction: sum of active levers before priming2.63.94.82.12.22.22.0-2.22.22.0-2.12.1-1.80.4
Active lever presses in extinction session 62.52.53.41.71.81.81.6-1.71.71.7-1.71.6-0.90.4
Bone: final force1.93.14.41.71.71.62.1-1.81.82.1-2.02.0-1.70.3
Bone: final moment2.03.24.41.81.81.72.1-1.81.82.1-2.02.0-1.70.3
Food consumed during 24 hour testing period0.10.21.00.0-0.1-0.2-0.00.4-0.4-0.30.5-0.40.4-1.0
Glucose1.42.24.0-1.9-2.0-1.9-0.81.8-1.8-0.91.1-1.10.4-1.4
Heart weight0.20.31.5-0.5-0.6-0.50.40.3-0.20.2-0.30.3-1.2-0.7
Delay discount hyperbolic model param0.10.10.6-0.0-0.0-0.0-0.30.2-0.2-0.50.4-0.40.7-0.1
Intermittent access intake day 1-15 change0.42.23.7-1.4-1.5-1.4-1.21.6-1.7-1.31.4-1.61.9-1.0
Intermittent access intake escalation0.52.74.5-1.6-1.7-1.6-1.41.8-1.8-1.41.6-1.82.1-1.0
Intermittent access intake escalation 20.40.71.6-0.7-0.8-0.8-0.50.9-0.9-0.50.7-0.81.3-0.7
Intermitt. access day 1 inactive lever presses0.11.52.4-1.3-1.2-1.4-1.31.3-1.3-1.01.2-1.31.50.0
Intermitt. access day 15 inactive lever presses0.31.53.20.80.90.81.8-1.00.91.7-1.61.4-1.1-1.2
Intermitt. access escalation Index0.30.91.2-0.9-1.0-0.9-1.11.0-0.9-1.11.1-1.00.7-0.3
Intermittent access day 1 total infusions0.41.13.8-0.9-0.6-0.81.10.3-0.31.3-1.10.8-1.2-2.0
Intermittent access day 15 total infusions1.23.05.9-2.3-2.1-2.2-0.72.0-2.1-0.60.9-1.21.1-2.4
Intermittent access terminal intake (last 3 days)0.61.15.1-1.3-1.1-1.10.60.8-1.00.7-0.50.1-0.1-2.3
Intermittent access total infusions0.91.04.3-1.4-1.1-1.20.50.8-0.90.6-0.40.1-0.3-2.1
Intermittent access day 1 locomotion0.40.61.5-0.5-0.2-0.31.0-0.10.01.2-1.10.9-1.2-1.0
Intermittent access day 15 total locomotion0.10.51.5-0.7-0.4-0.40.80.2-0.31.0-0.90.5-0.4-1.2
Intermittent access total locomotion1.11.33.7-0.8-0.4-0.51.50.0-0.21.7-1.51.1-1.0-1.9
Intermittent access standard deviation0.21.01.5-1.2-1.1-1.1-0.71.1-1.2-0.70.8-0.91.0-0.9
Left kidney weight0.00.41.7-0.6-0.6-0.60.70.4-0.50.4-0.40.2-0.4-1.3
Right kidney weight0.00.31.6-0.3-0.4-0.40.70.3-0.30.3-0.20.2-0.3-1.3
Cocaine induced anxiety0.00.10.50.10.10.1-0.0-0.10.10.1-0.0-0.00.40.7
Post-drug Anxiety0.20.30.40.60.60.60.5-0.60.60.5-0.50.5-0.20.3
Baseline Anxiety0.20.40.80.60.60.60.5-0.70.70.3-0.50.7-0.9-0.2
Tail length0.10.62.01.41.11.00.3-0.91.00.1-0.10.5-0.50.5
Length with tail1.04.58.22.92.62.51.9-2.42.41.6-1.82.0-1.90.1
Length without tail1.58.010.93.33.33.22.7-3.13.22.4-2.62.8-2.80.5
Times rat made contact with spout0.10.10.20.40.30.3-0.3-0.20.3-0.40.3-0.1-0.20.4
Lifetime Intake0.70.83.2-1.3-1.0-1.10.40.7-0.80.5-0.40.1-0.4-1.8
Liver weight, left1.01.72.1-1.3-1.3-1.3-1.31.5-1.4-1.41.4-1.41.0-0.6
Liver weight, right0.91.62.6-1.5-1.6-1.6-1.11.5-1.5-1.11.1-1.10.1-1.0
Locomotor activity0.91.42.8-1.1-1.0-1.1-1.61.1-1.1-1.71.5-1.30.50.1
Locomotor testing distance0.61.42.5-1.3-1.2-1.2-1.61.2-1.1-1.51.4-1.20.20.0
Locomotor testing rearing0.41.52.3-1.2-1.4-1.3-1.51.3-1.2-1.41.4-1.30.4-0.4
Locomotion in novel chamber1.21.62.9-1.7-1.5-1.6-0.71.5-1.6-0.80.9-1.10.9-1.1
Locomotion in novel chamber post-restriction0.82.43.5-1.9-1.8-1.7-1.31.8-1.8-1.31.5-1.61.70.1
Fecal boli incidents, locomotor time 10.10.31.1-0.4-0.4-0.4-0.10.5-0.6-0.10.3-0.40.9-1.1
Change in fecal boli incidents, locomotor task0.91.01.5-1.2-1.2-1.2-1.11.0-1.0-1.10.9-0.90.20.4
Time >=10cm from walls, locomotor time 11.11.32.8-1.4-1.2-1.5-0.31.3-1.4-0.30.5-0.81.1-1.7
Bouts of movement, locomotor time 10.40.62.50.30.60.2-0.6-0.10.1-0.60.7-0.61.31.6
Total resting periods, locomotor time 10.30.31.20.30.50.3-0.4-0.10.1-0.40.5-0.51.11.1
Rest time, locomotor task time 11.32.22.7-1.3-1.5-1.2-1.61.6-1.6-1.51.6-1.61.6-0.6
Distance moved, locomotor task time 10.20.60.90.60.60.60.9-0.70.70.9-0.90.9-1.0-0.3
Vertical activity count, locomotor time 10.10.40.7-0.8-0.7-0.8-0.50.7-0.7-0.50.5-0.50.3-0.3
Time >=10cm from walls, locomotor time 20.00.10.9-0.10.0-0.1-0.10.3-0.3-0.10.2-0.40.9-0.5
Bouts of movement, locomotor time 20.31.01.71.31.31.30.9-1.21.20.8-0.90.9-0.60.1
Total resting periods, locomotor time 20.10.40.80.90.80.90.6-0.80.80.5-0.60.6-0.30.0
Rest time, locomotor task time 21.93.34.3-2.0-2.1-2.0-1.82.0-2.0-1.71.8-1.81.6-0.3
Distance moved, locomotor task time 20.30.30.80.80.90.90.2-0.70.70.3-0.30.4-0.10.4
Vertical activity count, locomotor time 20.10.30.7-0.1-0.0-0.1-0.80.2-0.1-0.80.7-0.50.30.8
Light reinforcement 10.00.20.4-0.1-0.1-0.1-0.40.3-0.3-0.50.6-0.50.6-0.7
Light reinforcement 20.20.42.8-0.1-0.3-0.30.70.3-0.40.5-0.20.00.6-1.7
Bone: marrow area0.61.66.7-1.5-1.5-1.50.51.2-1.30.4-0.1-0.2-0.4-2.6
Bone: maximum diameter0.40.81.70.50.50.51.3-0.50.51.2-1.10.9-0.5-1.2
Bone: maximum force3.16.110.02.32.22.23.2-2.42.33.1-2.92.8-2.5-0.4
Bone: maximum moment3.26.09.62.32.22.23.1-2.42.33.0-2.82.7-2.5-0.4
Mean time between licks in bursts0.10.41.80.60.70.60.2-0.60.7-0.1-0.30.5-1.3-0.3
Mean num. licks in bursts0.10.20.6-0.3-0.3-0.1-0.80.3-0.2-0.60.6-0.50.30.7
Cd content in liver0.60.71.3-1.1-0.9-0.9-0.70.9-1.0-0.40.6-0.81.1-0.0
Co content in liver1.61.93.9-1.1-1.0-1.0-2.01.1-1.1-1.91.6-1.51.21.0
Cu content in liver0.10.20.8-0.2-0.1-0.1-0.50.2-0.1-0.50.4-0.30.30.9
Fe content in liver0.00.00.1-0.3-0.2-0.1-0.10.1-0.1-0.0-0.0-0.0-0.0-0.2
K content in liver0.60.61.30.90.60.51.0-0.70.70.8-0.90.9-1.1-0.1
Mg content in liver0.20.21.10.10.00.00.5-0.20.30.4-0.50.5-1.00.2
Mn content in liver3.03.44.52.12.12.02.0-2.02.01.9-1.81.9-1.40.6
Na content in liver0.50.50.90.80.60.71.0-0.70.70.8-0.80.8-0.7-0.0
Rb content in liver2.32.73.9-1.7-1.9-2.0-1.61.8-1.8-1.71.7-1.70.8-0.6
Se content in liver0.20.20.70.40.30.30.8-0.30.30.7-0.50.5-0.1-0.4
Sr content in liver3.42.94.22.02.02.01.5-2.02.01.5-1.61.7-1.10.7
Zn content in liver2.63.03.61.61.81.81.6-1.91.91.7-1.81.8-1.61.5
Bone: minimum diameter0.71.39.4-0.8-0.8-0.91.00.6-0.70.8-0.50.3-0.7-3.1
Time in familiar zone, hab. session 10.20.20.50.20.40.40.5-0.30.30.4-0.50.5-0.7-0.3
Time in novel zone, hab. session 11.31.52.1-1.2-1.3-1.3-1.41.3-1.2-1.41.4-1.31.0-0.3
Total zone transitions, hab. session 10.20.20.90.50.40.40.3-0.50.50.3-0.40.4-0.21.0
Total locomotion distance, hab. session 10.10.10.3-0.4-0.4-0.30.40.1-0.10.5-0.50.2-0.20.5
Locomotion velocity, hab. session 10.20.30.90.30.20.20.7-0.50.40.8-0.80.6-0.41.0
Time in familiar zone, hab. session 20.50.61.6-0.3-0.3-0.3-1.00.7-0.6-1.31.2-0.90.3-0.7
Time in novel zone, hab. session 20.80.81.70.60.60.61.1-0.90.81.3-1.31.1-0.80.6
Total zone transitions, hab. session 21.51.93.41.21.21.21.3-1.41.41.5-1.51.5-1.90.7
Total locomotion distance, hab. session 20.40.51.40.30.20.20.7-0.50.50.9-0.80.8-1.20.9
Locomotion velocity, hab. session 20.30.41.00.10.10.00.7-0.40.40.9-0.80.7-1.00.7
Novel to familiar place preference ratio1.62.12.81.61.51.41.7-1.61.61.7-1.61.6-0.90.2
Novelty place preference1.01.31.91.31.21.11.4-1.21.21.3-1.21.2-0.7-0.1
Time in novel zone, NPP test1.21.41.91.31.21.11.4-1.31.31.4-1.31.3-0.80.0
Total zone transitions, NPP test1.01.52.81.11.11.10.9-1.31.31.2-1.31.3-1.21.7
Total locomotion distance, NPP test0.30.42.7-0.00.0-0.00.2-0.30.40.6-0.60.5-0.71.7
Locomotion velocity, NPP test0.20.33.0-0.1-0.1-0.10.0-0.20.20.4-0.40.3-0.41.7
Intraocular pressure0.20.41.2-0.3-0.3-0.3-0.70.5-0.5-0.70.9-0.71.1-0.3
Delta distance traveled before/after self-admin0.70.81.8-0.8-0.6-0.6-1.20.8-0.7-1.41.2-1.00.60.2
Delta ambulatory time before/after self-admin0.71.32.6-1.0-0.9-0.9-1.51.0-1.0-1.61.5-1.30.80.3
Parametrial fat weight0.92.06.5-1.7-1.8-1.7-0.11.6-1.7-0.20.4-0.80.5-2.5
Pavlov. Cond. lever latency1.31.62.6-1.2-1.1-1.1-1.61.2-1.2-1.51.5-1.41.4-0.2
Pavlov. Cond. magazine entry latency1.51.93.51.31.31.31.9-1.31.21.7-1.71.5-1.20.5
Pavlov. Cond. change in total contacts0.60.61.50.70.70.71.2-0.60.61.2-1.00.8-0.40.6
Pavlov. Cond. index score0.81.11.81.11.01.11.3-1.00.91.2-1.21.1-0.80.4
Pavlov. Cond. latency score0.81.01.71.00.91.01.3-0.90.91.2-1.21.1-1.00.2
Pavlov. Cond. lever contacts0.80.91.70.80.80.81.3-0.80.81.2-1.21.1-1.20.0
Pavlov. Cond. magazine entry number0.81.01.4-1.1-1.1-1.2-1.11.0-1.0-1.01.0-0.90.4-0.9
Pavlov. Cond. intertrial magazine entries0.10.10.60.10.20.1-0.3-0.00.0-0.00.2-0.20.70.7
Pavlov. Cond. lever-magazine prob. diff.1.01.22.01.11.11.11.4-1.01.01.3-1.21.1-0.80.5
Pavlov. Cond. response bias1.11.42.21.31.21.21.5-1.11.11.3-1.31.2-0.80.8
Pavlov. Cond. lever latency0.71.01.5-1.0-1.0-1.1-1.20.9-0.9-1.11.0-1.00.81.0
Pavlov. Cond. magazine entry latency3.95.57.52.72.72.72.3-2.62.62.3-2.32.3-1.70.9
Pavlov. Cond. change in total contacts0.92.23.21.61.61.81.8-1.51.41.7-1.51.5-0.9-0.8
Pavlov. Cond. index score2.43.74.92.12.12.22.2-2.01.92.1-2.02.0-1.3-0.4
Pavlov. Cond. latency score2.23.54.82.02.02.12.2-1.91.82.1-2.01.9-1.3-0.2
Pavlov. Cond. lever contacts0.50.81.10.90.91.01.0-0.80.80.9-0.80.8-0.6-0.9
Pavlov. Cond. magazine entry number6.58.411.8-3.3-3.3-3.4-2.93.2-3.2-2.92.9-2.92.0-0.8
Pavlov. Cond. intertrial magazine entries1.12.33.0-1.6-1.7-1.5-1.51.6-1.6-1.51.5-1.61.7-0.3
Pavlov. Cond. lever-magazine prob. diff.2.74.15.72.22.22.42.3-2.12.12.2-2.12.1-1.4-0.3
Pavlov. Cond. response bias2.12.93.91.91.92.01.9-1.71.71.7-1.71.7-1.4-0.5
Time in closed arm before self-admin0.20.33.00.0-0.1-0.10.40.2-0.20.3-0.10.00.1-1.7
Time in closed arm after self-admin0.70.71.0-0.8-1.0-1.0-0.81.0-1.0-0.90.9-0.80.3-0.8
Time in open arm before self-admin1.11.32.5-1.2-1.1-1.1-1.61.0-0.8-1.61.2-1.10.21.2
Time in open arm after self-admin0.50.63.10.40.70.70.2-0.70.80.3-0.50.5-0.41.8
Bone: periosteal estimation0.51.14.70.10.00.01.5-0.20.11.4-1.10.9-1.0-2.2
Bone: periosteal perimeter0.30.73.80.10.10.11.1-0.10.11.0-0.80.6-0.5-1.9
Bone: post-yield work0.61.03.0-0.2-0.10.01.7-0.20.11.7-1.41.1-1.1-0.9
Progressive ratio test 1 active lever presses0.10.21.0-1.0-0.6-0.8-0.10.5-0.6-0.0-0.0-0.20.2-0.2
Progressive ratio test 1 breakpoint0.10.20.9-1.0-0.6-0.8-0.10.5-0.6-0.0-0.0-0.20.2-0.3
Progressive ratio test 1 inactive lever presses0.41.01.80.70.90.71.2-0.90.91.2-1.31.1-1.1-0.1
Progressive ratio test 2 active lever presses0.40.61.6-1.3-0.9-1.00.00.8-0.90.1-0.0-0.30.4-1.2
Progressive ratio test 2 breakpoint0.40.61.4-1.2-0.9-0.90.10.8-0.90.2-0.1-0.20.3-1.2
Progressive ratio test 2 inactive lever presses0.10.51.7-0.9-0.7-0.80.40.6-0.70.5-0.4-0.00.1-1.3
Incentive Sensitization - Responses0.51.32.60.70.80.91.6-0.90.91.6-1.51.3-1.1-0.8
Incentive Sensitization - Breakpoint0.51.12.30.60.70.81.5-0.80.71.5-1.41.2-1.0-0.9
Sum of active levers in priming session hrs 5-60.60.51.11.01.11.10.5-0.80.70.6-0.50.30.80.4
Progressive ratio0.20.63.90.10.30.01.1-0.10.10.8-0.60.6-0.7-2.0
Food seeking constrained by brief footshock0.10.10.7-0.2-0.1-0.3-0.10.2-0.2-0.10.1-0.1-0.1-0.8
Seeking ratio, punishment vs. effort0.20.42.1-0.2-0.4-0.2-0.80.1-0.1-0.60.4-0.30.01.5
Retroperitoneal fat weight2.410.817.9-3.9-4.2-4.2-2.43.9-3.9-2.52.6-2.91.9-2.7
Reaction time number correct0.10.51.01.00.90.90.5-0.70.80.1-0.30.5-0.6-0.6
Reaction time mean minus median0.10.40.90.80.80.90.5-0.60.50.4-0.40.30.60.4
Reaction time mean minus median AUC0.00.20.90.40.40.5-0.3-0.10.1-0.40.3-0.31.00.4
Reaction time num false alarms0.40.72.0-0.9-0.7-0.5-1.40.6-0.5-1.21.0-0.80.21.1
Reaction time num false alarms AUC0.20.42.0-0.3-0.10.1-1.10.10.0-0.90.7-0.4-0.11.4
Reaction time trials correct on left0.10.51.01.00.90.90.5-0.70.80.1-0.30.5-0.6-0.6
Reaction time trials on left0.10.51.01.00.90.90.5-0.70.80.1-0.30.5-0.6-0.6
Reaction time mean0.10.10.9-0.2-0.10.1-0.30.2-0.3-0.20.2-0.41.00.3
Reaction time mean AUC0.10.21.1-0.3-0.2-0.1-0.40.4-0.4-0.30.3-0.51.0-0.3
Median of all reaction times0.00.00.3-0.2-0.10.1-0.20.1-0.20.00.0-0.20.60.2
Reaction time omissions0.10.20.70.60.60.8-0.2-0.50.5-0.1-0.00.10.50.8
Reaction time false alarm rate0.40.61.8-0.9-0.7-0.5-1.20.5-0.4-0.80.7-0.60.21.4
Reaction time premature initiation rate3.75.78.72.62.42.52.4-2.62.62.0-2.42.6-3.00.4
Reaction time premature initiations2.16.39.23.02.82.92.3-2.82.91.8-2.22.6-2.80.4
Std. dev. reaction times0.10.42.1-0.3-0.10.1-0.70.4-0.4-0.70.6-0.71.50.7
Reaction time trials completed0.10.51.01.00.90.90.5-0.70.80.1-0.30.5-0.6-0.6
Reaction time trials AUC0.10.40.80.90.80.80.4-0.70.70.1-0.30.5-0.6-0.6
Run reversals in cocaine runway, females0.80.93.20.50.50.51.0-0.80.81.0-1.11.1-1.8-0.4
Run reversals in cocaine runway, males0.60.60.9-0.7-0.7-0.8-0.90.8-0.8-0.90.9-0.90.80.1
Latency to leave start box in cocaine runway0.20.20.9-0.6-0.7-0.60.10.5-0.50.00.0-0.1-0.1-0.9
Latency to leave start box in cocaine runway, F0.10.10.20.20.20.20.4-0.20.20.4-0.40.4-0.4-0.3
Latency to leave start box in cocaine runway, M1.51.42.3-1.5-1.5-1.5-0.81.4-1.4-0.80.9-1.00.6-1.0
Std. dev. time between licks in bursts0.10.20.8-0.2-0.2-0.3-0.50.3-0.2-0.80.5-0.3-0.4-0.9
Total sessions with >9 infusions0.50.61.4-1.2-1.0-1.0-0.30.9-0.9-0.30.4-0.50.2-0.9
Short access day 1 total inactive lever presses0.10.20.4-0.5-0.1-0.10.4-0.00.00.5-0.60.4-0.7-0.3
Short access day 10 total inactive lever presses0.10.71.0-0.9-0.8-0.8-1.00.9-0.9-0.90.9-0.90.80.3
Short access day 1 total infusions0.51.02.1-1.5-1.4-1.3-0.51.1-1.2-0.40.5-0.70.2-1.2
Short access day 10 total infusions0.40.72.7-0.7-0.5-0.60.80.2-0.30.9-0.80.6-0.9-1.6
Short access total infusions0.40.61.9-1.1-0.9-1.00.20.6-0.60.3-0.30.1-0.6-1.4
Short access day 1 locomotion0.10.20.6-0.8-0.6-0.60.10.4-0.40.3-0.2-0.0-0.2-0.7
Short access day 10 total locomotion0.20.71.6-0.10.10.11.2-0.40.31.3-1.21.0-1.0-0.9
Short access total locomotion0.20.30.7-0.6-0.3-0.40.70.1-0.20.8-0.70.5-0.6-0.8
One hour access (0.3 mA shock)0.70.82.3-1.3-1.2-1.10.10.9-1.00.20.0-0.20.1-1.5
Compulsive drug intake0.40.51.31.10.91.10.0-0.80.9-0.10.00.2-0.51.0
One hour access (shock baseline)1.02.65.1-2.3-2.1-2.2-0.61.8-1.9-0.40.7-1.01.1-1.9
Social response proportion0.00.10.30.50.10.10.2-0.10.10.0-0.10.1-0.2-0.5
Social responses0.10.10.30.40.20.2-0.4-0.00.1-0.50.5-0.30.2-0.1
Social time0.10.20.60.0-0.2-0.1-0.60.2-0.2-0.80.7-0.60.50.3
Soleus weight2.67.610.0-3.1-3.0-3.2-2.63.1-3.0-2.52.6-2.82.2-1.9
Bone: stiffness0.81.42.81.21.21.01.7-1.11.01.5-1.41.2-0.8-0.3
Tibialis anterior weight7.626.034.55.95.95.84.9-5.85.84.8-4.95.2-4.11.8
Time to tail flick, vehicle, before self-admin0.40.51.40.30.30.41.0-0.50.51.2-1.10.9-0.9-0.1
Time to tail flick, vehicle, after self-admin0.30.61.40.50.50.50.9-0.70.70.9-0.90.9-1.2-0.7
Time to tail flick, test, before self-admin0.91.03.20.30.50.51.2-0.80.81.2-1.21.3-1.8-0.0
Time to tail flick, test, after self-admin0.00.00.10.30.20.20.3-0.10.10.2-0.20.10.2-0.1
Delta time to tail flick, vehicle, before/after SA0.10.10.30.50.40.30.3-0.50.50.2-0.30.4-0.5-0.0
Delta time to tail flick, test, before/after SA0.40.42.40.20.10.1-0.70.3-0.3-0.70.7-0.81.60.4
Tibia length1.44.06.02.12.12.02.3-2.02.02.5-2.22.0-0.91.3
Ambulatory time before self-admin0.82.43.41.61.61.61.8-1.61.51.8-1.71.6-1.0-0.5
Ambulatory time after self-admin0.10.20.50.40.60.50.6-0.40.40.4-0.30.4-0.2-0.7
Bone: tissue strength0.40.41.1-0.3-0.5-0.6-0.40.6-0.6-0.80.7-0.60.4-1.0
Total heroin consumption4.24.97.42.72.72.71.6-2.62.61.7-1.81.9-1.22.2
Bone: trabecular number1.42.53.91.31.41.42.0-1.51.52.0-1.91.8-1.7-0.6
Bone: trabecular spacing0.81.22.4-0.7-0.9-0.9-1.51.0-1.0-1.51.4-1.31.00.4
Bone: trabecular thickness0.10.10.9-0.4-0.3-0.30.00.3-0.40.00.1-0.20.3-1.0
Bone: trabecular tissue density4.78.210.3-3.0-3.0-2.9-3.23.0-3.0-3.02.9-3.13.1-0.2
Water consumed over 24 hours0.20.51.11.10.90.90.5-0.80.80.1-0.30.5-0.6-0.5
Number of responses in last shaping day0.10.10.40.30.30.30.1-0.40.40.3-0.30.3-0.50.6