Hub : Genes

Tigd3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA isoform ratio XM_006230805.5 0.04 0.03 4.3e-03 0.02 0.02 0.02 0.02 5.9e-03 6.2e-03 5.6e-03 5.2e-03
2 pVTA isoform ratio NM_001107573.1 0.04 0.03 3.4e-03 0.02 0.03 0.02 0.03 5.0e-03 4.2e-03 4.4e-03 4.0e-03
3 PL gene expression Tigd3 0.06 0.03 6.2e-08 0.07 0.08 0.08 0.08 1.9e-08 5.2e-09 3.4e-09 4.3e-09
4 NAcc gene expression Tigd3 0.07 0.04 5.1e-12 0.07 0.08 0.08 0.08 9.3e-11 1.7e-12 1.2e-11 1.5e-11
5 BLA gene expression Tigd3 0.09 0.05 1.8e-04 0.09 0.06 0.08 0.06 2.7e-05 2.3e-04 4.8e-05 2.8e-04
6 Eye isoform ratio NM_001107573.1 0.44 0.19 9.9e-03 0.07 0.15 0.13 0.14 3.0e-02 2.8e-03 4.4e-03 4.2e-03
7 Brain gene expression Tigd3 0.14 0.07 1.1e-14 0.15 0.13 0.13 0.06 4.6e-14 3.8e-12 3.2e-12 5.6e-06
8 Eye isoform ratio XM_006230805.5 0.45 0.19 6.8e-03 0.07 0.16 0.14 0.14 2.9e-02 1.7e-03 3.3e-03 3.5e-03
9 Adipose gene expression Tigd3 0.19 0.08 0.0e+00 0.14 0.15 0.15 0.14 2.0e-15 2.3e-16 5.1e-16 1.1e-15
10 Liver gene expression Tigd3 0.12 0.06 1.2e-11 0.07 0.08 0.07 0.07 1.6e-08 5.9e-09 2.1e-08 2.7e-08
11 Eye alternative TSS XM_006230805.5 0.41 0.21 7.9e-03 0.06 0.12 0.04 0.05 5.2e-02 7.1e-03 7.0e-02 6.3e-02
12 Eye alternative TSS NM_001107573.1 0.45 0.21 5.1e-03 0.05 0.11 0.04 0.05 6.6e-02 8.8e-03 8.2e-02 6.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.01.93.8-0.90.9-0.50.3-1.4-1.4-0.81.41.91.91.9-1.8
Area under the delay curve0.20.30.80.1-0.1-0.50.6-0.4-0.2-0.30.20.60.70.9-0.9
BMI with tail2.89.721.7-2.22.2-0.90.3-1.9-3.1-1.53.04.74.54.5-4.4
BMI without tail0.52.56.1-1.41.4-0.3-0.0-0.4-1.1-0.71.02.32.32.5-2.4
Body weight1.14.913.1-3.63.61.6-2.10.0-1.31.21.22.62.22.2-2.1
Weight adjusted by age0.30.92.2-1.41.41.5-1.41.1-0.11.30.0-0.0-0.3-0.30.4
Bone surface2.24.29.7-3.13.11.2-1.6-0.7-2.30.72.22.52.01.8-1.8
Bone volume1.63.25.9-1.81.80.1-0.3-1.3-2.4-0.32.32.42.12.0-1.9
Breakpoint value in progressive ratio session0.71.33.8-2.02.01.4-1.40.8-0.81.00.70.80.50.5-0.5
Number of licking bursts0.10.20.4-0.70.70.5-0.40.2-0.50.20.40.30.20.2-0.2
Context. condit. distance diff. score0.91.02.81.7-1.7-1.41.5-0.90.3-1.3-0.2-0.20.10.2-0.2
Locomotion velocity, session 10.40.41.2-0.20.20.4-0.50.51.10.6-1.1-0.7-0.7-0.60.6
Locomotion distance, session 10.50.61.6-0.80.8-0.1-0.1-0.4-0.3-0.30.31.21.21.2-1.2
Locomotion velocity, session 21.11.34.1-2.02.00.9-1.1-0.1-0.50.60.41.21.01.0-1.0
Locomotion distance, session 20.40.51.1-1.01.00.3-0.30.0-0.10.10.10.90.91.0-1.0
Locomotion velocity, session 30.91.02.60.5-0.5-1.10.8-1.6-0.4-1.00.51.21.21.2-1.2
Locomotion distance, session 30.00.00.10.2-0.2-0.10.1-0.20.1-0.1-0.10.00.00.0-0.0
Stereotopy head waving bouts, day 30.91.12.31.0-1.0-1.41.1-1.5-0.2-1.00.21.01.11.1-1.2
Stereotopy head waving duration, day 30.70.81.61.0-1.0-1.31.1-1.2-0.4-1.00.40.70.80.8-0.8
Locomotion velocity, session 72.12.33.60.6-0.6-1.61.5-1.6-1.2-1.91.21.71.81.9-1.9
Locomotion distance, session 70.20.30.80.2-0.1-0.60.4-0.60.1-0.6-0.10.60.80.9-0.9
Stereotopy head waving bouts, day 70.81.02.00.2-0.2-0.70.8-0.8-1.4-1.01.41.11.11.0-1.0
Stereotopy head waving duration, day 70.81.02.3-0.80.80.10.0-0.2-1.5-0.51.51.31.21.2-1.2
Locomotion velocity, session 81.01.22.3-1.11.11.2-1.50.71.21.5-1.3-0.7-0.8-0.80.8
Locomotion distance, session 80.70.91.80.5-0.5-1.21.0-1.3-0.5-1.10.61.01.11.1-1.1
Degree of sensitization distance0.40.51.0-0.00.0-0.60.4-0.8-0.3-0.50.31.01.01.0-1.0
Degree of sensitization stereotypy0.70.82.4-0.60.60.10.1-0.2-1.6-0.51.51.11.00.9-0.9
Conditioned locomotion0.70.81.9-1.41.41.2-1.40.70.21.2-0.30.1-0.0-0.10.1
Cocaine response after cond. corrected0.50.72.01.4-1.4-1.00.9-0.61.0-0.5-0.9-0.4-0.2-0.20.1
Cocaine response after cond. not corrected0.40.51.61.3-1.3-0.90.7-0.60.8-0.5-0.7-0.3-0.2-0.10.1
Cocaine response before conditioning0.30.40.9-1.01.00.7-0.60.4-0.80.30.80.40.30.2-0.2
Saline control response1.72.46.3-2.52.52.2-2.31.30.51.8-0.70.1-0.2-0.20.2
Bone: connectivity density1.42.24.1-2.02.00.6-0.8-0.6-1.40.01.32.01.71.7-1.7
Bone: cortical apparent density0.30.41.6-0.30.30.8-0.41.20.50.5-0.5-0.8-0.7-0.60.6
Bone: cortical area0.30.41.2-1.11.10.7-0.9-0.4-0.60.70.50.50.30.1-0.1
Bone: cortical porosity0.20.20.3-0.50.50.0-0.1-0.1-0.4-0.10.30.50.50.6-0.6
Bone: cortical porosity0.30.30.8-0.90.90.3-0.40.0-0.30.10.30.60.50.6-0.6
Bone: cortical thickness2.43.97.3-2.32.32.7-2.72.11.32.5-1.4-1.2-1.4-1.41.5
Bone: cortical thickness1.51.93.2-0.70.71.4-1.41.51.81.5-1.8-1.3-1.3-1.21.2
Bone: cortical tissue density0.40.62.1-0.50.51.0-0.61.40.60.7-0.6-0.9-0.8-0.70.7
Condit. Reinf. active minus inactive responses0.10.10.3-0.30.30.1-0.00.2-0.2-0.00.10.40.40.5-0.5
Condit. Reinf. active-inactive response ratio0.00.00.5-0.10.10.20.00.70.1-0.0-0.1-0.2-0.10.0-0.0
Condit. Reinf. active responses0.40.50.9-0.10.1-0.50.4-0.7-0.7-0.50.70.90.91.0-1.0
Condit. Reinf. inactive responses0.91.22.90.3-0.3-1.00.8-1.7-1.1-1.01.11.31.31.2-1.2
Incentive salience index mean0.40.51.3-0.50.5-0.20.1-0.4-0.6-0.30.61.11.11.1-1.1
Condit. Reinf. lever presses0.60.92.0-0.80.8-0.1-0.1-0.9-1.2-0.31.11.41.31.2-1.2
Condit. Reinf. active minus inactive responses0.20.41.00.2-0.2-0.50.5-0.6-1.0-0.71.00.60.50.4-0.4
Condit. Reinf. active-inactive response ratio1.11.73.60.8-0.8-1.41.2-1.9-1.7-1.41.71.21.20.9-1.0
Condit. Reinf. active responses0.20.30.8-0.40.40.00.20.1-0.9-0.40.90.60.60.6-0.6
Condit. Reinf. inactive responses0.20.31.4-0.90.90.8-0.51.20.30.3-0.30.00.10.3-0.3
Condit. Reinf. lever presses0.91.33.1-1.81.80.9-1.00.1-1.50.41.41.20.90.7-0.7
Condit. Reinf. lever reinforcers received0.20.30.8-0.80.80.4-0.20.4-0.9-0.10.80.50.50.5-0.5
Conditioned reinforcement - actives0.10.31.4-0.10.00.1-0.1-0.2-1.20.31.20.30.0-0.30.3
Conditioned reinforcement - inactives0.61.64.42.1-2.1-1.51.7-0.9-1.1-1.21.2-0.1-0.1-0.30.2
Conditioned locomotion2.23.310.63.3-3.3-2.32.6-1.0-0.4-1.70.5-0.8-0.6-0.70.6
Patch foraging indifference point 0 sec0.00.10.10.2-0.2-0.20.3-0.2-0.2-0.10.20.20.30.3-0.3
Patch foraging indifference point AUC0.61.53.9-2.02.01.8-1.61.5-0.71.10.60.1-0.1-0.20.3
Delay disc. indifference point, 0s delay0.60.71.40.4-0.4-1.01.1-0.9-0.2-0.90.30.81.01.1-1.2
Delay disc. indifference point, 16s delay0.50.81.71.0-1.0-1.01.3-0.8-0.8-0.90.80.50.70.8-0.8
Delay disc. indifference point, 2s delay0.40.40.90.3-0.3-0.80.7-1.0-0.6-0.60.60.70.70.7-0.7
Delay disc. indifference point, 24s delay0.20.41.00.2-0.20.1-0.20.51.00.9-1.0-0.7-0.6-0.50.5
Delay disc. indifference point, 4s delay0.20.20.40.2-0.2-0.40.5-0.30.4-0.2-0.40.30.50.6-0.6
Delay disc. indifference point, 8s delay0.00.10.20.0-0.0-0.20.3-0.10.4-0.1-0.40.10.20.4-0.4
Indifference point function ln k1.64.814.33.8-3.8-2.82.7-2.41.4-1.9-1.2-0.8-0.3-0.20.1
Indifference point function log k1.64.814.33.8-3.8-2.82.7-2.41.4-1.9-1.2-0.8-0.3-0.20.1
Patch foraging total patch changes 0 sec0.00.10.30.1-0.10.2-0.20.20.50.5-0.5-0.4-0.3-0.30.3
Patch foraging total patch changes 12 sec1.72.36.8-2.62.62.0-1.81.7-0.51.20.40.70.50.5-0.4
Patch foraging total patch changes 18 sec0.20.41.0-1.01.00.5-0.40.1-0.80.10.80.80.70.6-0.6
Patch foraging total patch changes 24 sec0.51.83.6-1.91.81.9-1.91.60.41.7-0.5-0.4-0.7-0.70.8
Patch foraging total patch changes 6 sec0.30.51.5-1.21.21.0-1.00.50.20.8-0.20.30.20.3-0.2
Patch foraging time to switch 0 sec0.93.57.0-1.71.7-0.10.0-0.7-2.3-0.72.22.62.52.4-2.4
Patch foraging water rate 0 sec1.03.87.02.6-2.6-0.90.9-0.61.9-0.0-1.8-2.5-2.3-2.32.3
Patch foraging water rate 12 sec1.87.314.53.8-3.8-1.61.5-0.93.1-0.2-3.0-3.3-2.9-2.82.7
Patch foraging water rate 18 sec1.02.24.82.2-2.2-1.20.9-0.81.9-0.2-1.8-1.5-1.3-1.21.2
Patch foraging water rate 24 sec2.13.06.72.6-2.6-1.11.1-1.31.8-0.3-1.7-2.0-1.7-1.81.7
Patch foraging water rate 6 sec2.94.37.72.6-2.6-0.90.8-1.02.80.2-2.6-2.5-2.2-2.22.1
Seeking ratio, delayed vs. immediate footshock0.40.50.90.6-0.6-0.60.9-0.1-0.5-1.00.50.60.80.9-1.0
Distance traveled before self-admin0.40.92.3-0.90.90.0-0.1-0.4-1.5-0.31.51.31.11.1-1.0
Distance traveled after self-admin0.10.10.3-0.50.50.6-0.30.5-0.40.20.30.0-0.00.00.0
Extensor digitorum longus weight2.710.834.6-5.95.94.1-4.42.4-0.73.20.51.81.11.1-1.0
Bone: elastic displacement1.82.34.71.0-1.00.3-0.30.52.20.8-2.1-2.0-1.9-1.91.8
Bone: elastic work1.41.93.1-1.11.11.5-1.61.11.71.6-1.8-1.1-1.2-1.11.1
Bone: endosteal estimation1.94.611.21.3-1.3-2.52.0-3.4-1.8-2.01.92.32.32.1-2.2
Bone: endosteal perimeter2.45.913.11.5-1.5-2.82.3-3.6-2.5-2.32.62.52.52.3-2.3
Epididymis fat weight1.15.712.83.3-3.3-3.43.1-3.6-1.3-2.71.50.50.70.4-0.5
Delta time in closed arm before/after self-admin0.80.72.6-0.30.30.6-0.80.61.60.9-1.6-0.6-0.6-0.40.4
Delta time in open arm before/after self-admin0.20.31.5-0.50.50.3-0.2-0.0-1.20.01.20.30.20.1-0.0
Diff in mean of infusions in LGA sessions0.20.40.9-0.80.81.0-0.90.80.30.8-0.4-0.3-0.4-0.40.4
Delay discount exponential model param0.10.20.50.0-0.00.3-0.40.20.10.1-0.1-0.4-0.6-0.70.7
Extinction: sum of active levers before priming0.91.32.6-1.61.61.0-0.80.6-1.10.21.01.41.21.3-1.2
Active lever presses in extinction session 61.31.33.5-1.91.91.3-1.50.3-1.01.10.90.80.40.2-0.1
Bone: final force0.91.54.6-2.12.11.2-1.5-0.1-0.81.10.71.10.80.6-0.6
Bone: final moment0.81.34.2-2.02.01.2-1.5-0.1-0.71.10.61.00.70.6-0.5
Food consumed during 24 hour testing period0.20.40.9-0.30.30.7-0.50.60.00.5-0.0-0.7-0.8-0.90.9
Glucose2.54.07.52.1-2.1-2.72.6-2.4-0.9-2.51.01.41.71.7-1.8
Heart weight1.72.84.81.3-1.2-2.21.8-2.2-0.3-2.00.41.61.81.9-2.0
Delay discount hyperbolic model param0.20.20.6-0.00.00.5-0.50.40.20.3-0.2-0.6-0.7-0.80.8
Intermittent access intake day 1-15 change0.10.61.81.3-1.3-0.81.0-0.2-0.6-0.60.6-0.4-0.4-0.50.5
Intermittent access intake escalation0.10.51.41.2-1.2-0.70.8-0.2-0.6-0.50.7-0.4-0.4-0.60.6
Intermittent access intake escalation 20.30.41.21.1-1.1-0.60.8-0.2-0.6-0.50.7-0.4-0.4-0.50.5
Intermitt. access day 1 inactive lever presses0.00.21.60.4-0.4-0.10.31.3-0.1-0.20.1-0.3-0.2-0.20.2
Intermitt. access day 15 inactive lever presses0.31.73.11.7-1.7-1.61.8-0.9-1.4-1.71.40.60.60.5-0.5
Intermitt. access escalation Index0.62.04.32.1-2.1-2.12.0-2.00.1-1.8-0.0-0.10.20.4-0.4
Intermittent access day 1 total infusions2.16.29.71.9-1.9-3.12.8-3.0-2.3-2.92.42.22.42.2-2.3
Intermittent access day 15 total infusions1.94.68.72.8-2.8-2.92.8-2.2-1.9-2.62.10.91.00.7-0.8
Intermittent access terminal intake (last 3 days)3.15.49.62.5-2.5-3.12.8-2.8-2.3-2.72.51.51.51.2-1.3
Intermittent access total infusions4.45.29.12.2-2.2-3.02.7-2.8-2.2-2.72.31.71.81.6-1.6
Intermittent access day 1 locomotion1.93.55.81.7-1.7-2.42.3-1.9-1.6-2.31.71.51.71.6-1.6
Intermittent access day 15 total locomotion1.24.77.92.5-2.5-2.82.8-2.2-2.3-2.62.51.21.31.0-1.1
Intermittent access total locomotion7.38.714.43.0-3.0-3.83.7-3.4-3.0-3.53.22.02.21.9-2.0
Intermittent access standard deviation0.10.62.01.4-1.4-0.91.00.1-0.2-0.50.2-0.5-0.4-0.60.5
Left kidney weight0.43.06.01.6-1.6-2.42.1-2.5-1.2-2.31.31.11.21.1-1.2
Right kidney weight0.10.71.81.1-1.1-1.21.0-1.4-0.4-1.00.40.10.1-0.0-0.0
Cocaine induced anxiety0.00.10.4-0.10.1-0.00.00.3-0.7-0.20.70.30.20.2-0.2
Post-drug Anxiety0.30.30.8-0.90.90.8-0.70.4-0.40.30.40.30.20.1-0.1
Baseline Anxiety0.40.61.1-0.70.71.0-1.00.81.00.8-1.1-0.6-0.6-0.60.6
Tail length0.63.14.8-1.51.52.1-2.02.21.72.0-1.8-1.5-1.6-1.51.6
Length with tail1.25.311.1-3.13.13.2-3.32.21.43.1-1.5-0.8-1.1-1.11.2
Length without tail0.94.710.0-2.72.72.9-3.21.61.63.2-1.7-0.9-1.2-1.31.3
Times rat made contact with spout0.30.31.2-0.80.80.8-0.51.10.40.4-0.5-0.2-0.10.0-0.0
Lifetime Intake3.13.86.81.9-1.9-2.62.3-2.5-1.7-2.21.81.51.61.4-1.5
Liver weight, left0.30.61.51.2-1.2-0.90.6-1.10.8-0.3-0.7-0.5-0.4-0.40.4
Liver weight, right0.91.64.42.1-2.1-1.51.2-1.01.4-0.6-1.3-0.7-0.5-0.50.4
Locomotor activity1.52.34.61.8-1.8-0.60.5-0.02.10.4-2.0-1.9-1.7-1.71.6
Locomotor testing distance1.33.37.02.1-2.1-0.50.5-0.02.60.5-2.5-2.3-2.0-2.01.9
Locomotor testing rearing0.62.44.72.1-2.1-0.60.80.12.20.0-2.1-1.9-1.6-1.51.4
Locomotion in novel chamber2.12.86.72.6-2.6-2.42.3-2.1-0.6-2.00.70.00.20.1-0.1
Locomotion in novel chamber post-restriction0.72.04.42.1-2.1-2.02.1-1.6-0.7-1.70.80.00.20.2-0.2
Fecal boli incidents, locomotor time 10.20.52.2-0.20.2-0.00.3-0.5-1.5-0.61.50.70.60.4-0.4
Change in fecal boli incidents, locomotor task0.10.10.70.1-0.1-0.1-0.1-0.10.80.3-0.80.10.10.2-0.2
Time >=10cm from walls, locomotor time 13.54.36.70.8-0.8-2.01.8-2.6-2.5-2.22.62.32.32.1-2.1
Bouts of movement, locomotor time 11.21.65.4-1.51.52.2-1.32.3-0.01.1-0.1-0.6-0.7-0.60.7
Total resting periods, locomotor time 10.80.93.3-1.21.21.7-0.91.8-0.40.70.3-0.3-0.4-0.30.3
Rest time, locomotor task time 10.30.51.51.2-1.2-0.70.9-0.8-0.1-0.70.1-0.4-0.3-0.50.4
Distance moved, locomotor task time 10.20.61.3-0.20.2-0.80.3-0.7-0.5-0.50.51.01.11.1-1.1
Vertical activity count, locomotor time 10.10.51.51.2-1.2-1.10.9-0.70.2-0.6-0.2-0.2-0.0-0.0-0.0
Time >=10cm from walls, locomotor time 20.10.41.4-0.40.4-0.10.2-0.2-1.2-0.51.20.60.50.5-0.5
Bouts of movement, locomotor time 20.10.31.0-0.80.81.0-0.51.0-0.20.60.2-0.0-0.00.1-0.0
Total resting periods, locomotor time 20.00.20.4-0.50.50.6-0.10.6-0.40.20.40.20.20.3-0.3
Rest time, locomotor task time 20.71.22.71.6-1.6-1.51.6-1.6-0.3-1.40.40.20.30.3-0.3
Distance moved, locomotor task time 20.60.81.6-1.21.21.1-1.31.30.41.2-0.5-0.4-0.5-0.40.5
Vertical activity count, locomotor time 20.81.83.20.1-0.10.7-1.01.11.81.3-1.8-1.7-1.7-1.61.6
Light reinforcement 10.10.30.50.3-0.30.1-0.10.50.60.4-0.6-0.7-0.7-0.60.6
Light reinforcement 20.30.81.51.0-1.0-1.10.9-1.2-1.1-0.71.20.30.20.0-0.0
Bone: marrow area2.04.811.61.3-1.3-2.62.1-3.4-1.8-2.11.92.32.42.2-2.2
Bone: maximum diameter0.30.61.7-0.50.5-0.1-0.3-1.3-1.30.31.30.90.60.4-0.4
Bone: maximum force1.63.26.3-2.52.50.8-1.2-0.8-2.00.51.92.42.01.8-1.8
Bone: maximum moment1.62.95.7-2.42.40.7-1.1-0.9-1.80.51.72.31.91.8-1.7
Mean time between licks in bursts0.21.22.8-0.50.51.0-1.11.01.71.3-1.7-0.9-0.9-0.80.8
Mean num. licks in bursts0.10.20.50.5-0.5-0.20.30.30.7-0.2-0.7-0.5-0.3-0.20.2
Cd content in liver0.80.91.71.2-1.2-1.21.3-0.9-1.1-1.21.10.30.30.2-0.2
Co content in liver2.32.75.61.2-1.20.30.01.32.20.4-2.2-2.4-2.1-1.91.9
Cu content in liver0.20.30.70.2-0.2-0.30.60.0-0.5-0.80.50.50.60.7-0.7
Fe content in liver0.20.30.7-0.40.40.5-0.8-0.00.50.9-0.5-0.3-0.4-0.50.5
K content in liver0.40.40.8-0.60.6-0.0-0.2-0.8-0.2-0.10.20.90.80.9-0.9
Mg content in liver0.30.41.00.7-0.7-0.80.7-1.00.2-0.7-0.20.30.40.5-0.5
Mn content in liver1.21.44.3-2.12.11.5-1.60.4-0.81.20.70.70.30.2-0.1
Na content in liver0.50.51.2-0.70.70.8-1.10.40.41.0-0.5-0.5-0.7-0.80.8
Rb content in liver0.81.02.71.6-1.6-1.21.3-1.00.7-1.1-0.6-0.4-0.10.0-0.1
Se content in liver0.30.31.00.4-0.4-0.60.5-1.0-0.9-0.50.90.40.30.2-0.2
Sr content in liver1.71.53.1-1.71.71.6-1.81.30.21.5-0.3-0.5-0.8-0.80.8
Zn content in liver0.10.10.3-0.50.50.4-0.30.50.1-0.1-0.10.10.20.3-0.3
Bone: minimum diameter2.65.08.81.2-1.2-2.42.2-3.0-2.0-2.42.12.32.52.4-2.5
Time in familiar zone, hab. session 10.50.50.90.5-0.5-0.90.8-0.8-0.5-0.80.50.60.70.7-0.7
Time in novel zone, hab. session 10.91.02.30.4-0.40.5-0.50.51.50.8-1.5-1.3-1.3-1.21.2
Total zone transitions, hab. session 10.30.41.0-1.01.00.6-0.40.6-0.50.20.40.60.50.6-0.6
Total locomotion distance, hab. session 10.60.91.30.6-0.6-1.11.0-1.0-0.7-1.10.81.01.11.1-1.1
Locomotion velocity, hab. session 10.40.51.00.1-0.1-0.60.6-0.5-0.7-0.70.70.91.01.0-1.0
Time in familiar zone, hab. session 20.80.92.60.2-0.20.5-0.60.41.61.1-1.6-1.0-1.0-1.01.0
Time in novel zone, hab. session 20.50.51.1-0.30.3-0.20.4-0.1-1.1-0.81.00.80.80.9-0.9
Total zone transitions, hab. session 21.41.84.0-1.41.4-0.0-0.1-0.3-1.1-0.61.01.91.92.0-2.0
Total locomotion distance, hab. session 21.21.53.30.0-0.0-1.10.9-1.2-0.8-1.20.81.61.71.8-1.8
Locomotion velocity, hab. session 21.62.13.80.3-0.3-1.41.2-1.5-1.1-1.51.21.81.91.9-2.0
Novel to familiar place preference ratio0.81.02.9-1.11.10.4-0.30.3-1.7-0.21.61.10.90.8-0.8
Novelty place preference0.60.72.4-0.70.70.2-0.00.2-1.5-0.41.50.90.80.8-0.7
Time in novel zone, NPP test0.40.51.6-0.60.60.1-0.00.1-1.3-0.31.20.80.70.6-0.6
Total zone transitions, NPP test1.01.44.1-2.02.00.9-1.00.4-0.80.40.71.31.11.2-1.1
Total locomotion distance, NPP test0.40.61.4-0.30.3-0.50.4-0.6-0.5-0.60.51.11.11.2-1.2
Locomotion velocity, NPP test0.40.61.4-0.40.4-0.40.4-0.4-0.7-0.60.71.11.11.2-1.2
Intraocular pressure0.40.61.41.2-1.2-0.30.60.6-0.4-0.30.4-0.8-0.9-1.01.0
Delta distance traveled before/after self-admin1.01.12.50.4-0.40.6-0.41.01.60.6-1.6-1.4-1.3-1.11.1
Delta ambulatory time before/after self-admin0.71.12.50.2-0.20.8-0.61.21.60.7-1.6-1.3-1.2-1.11.1
Parametrial fat weight2.56.012.43.0-3.0-3.53.3-3.0-1.5-3.11.71.21.51.4-1.4
Pavlov. Cond. lever latency0.30.30.70.6-0.6-0.00.10.40.60.1-0.5-0.8-0.8-0.80.8
Pavlov. Cond. magazine entry latency0.91.22.3-0.40.4-0.40.4-0.6-1.4-0.91.31.51.51.5-1.5
Pavlov. Cond. change in total contacts1.01.12.9-0.20.2-0.40.6-0.5-1.7-0.91.71.21.21.2-1.2
Pavlov. Cond. index score0.20.30.7-0.50.50.1-0.1-0.1-0.8-0.20.80.70.60.6-0.6
Pavlov. Cond. latency score0.30.30.6-0.40.4-0.10.1-0.3-0.7-0.30.70.80.80.8-0.8
Pavlov. Cond. lever contacts0.30.30.7-0.30.3-0.30.1-0.6-0.5-0.30.50.80.80.9-0.8
Pavlov. Cond. magazine entry number0.20.20.70.5-0.5-0.40.2-0.30.8-0.1-0.8-0.3-0.3-0.30.3
Pavlov. Cond. intertrial magazine entries0.20.30.70.8-0.8-0.40.5-0.1-0.0-0.20.1-0.6-0.5-0.60.5
Pavlov. Cond. lever-magazine prob. diff.0.40.51.1-0.60.60.1-0.1-0.1-1.0-0.31.00.90.90.9-0.8
Pavlov. Cond. response bias0.10.20.5-0.40.40.3-0.20.1-0.7-0.00.70.40.40.4-0.3
Pavlov. Cond. lever latency0.30.41.01.0-1.0-0.50.60.31.0-0.3-0.9-0.6-0.4-0.20.2
Pavlov. Cond. magazine entry latency1.52.16.2-2.52.51.5-1.40.8-1.20.81.01.21.01.0-1.0
Pavlov. Cond. change in total contacts0.81.95.0-1.71.70.7-0.50.0-2.2-0.22.11.51.31.2-1.1
Pavlov. Cond. index score1.11.74.0-2.02.01.0-1.00.1-1.70.31.61.41.11.0-1.0
Pavlov. Cond. latency score1.01.63.3-1.81.80.8-0.8-0.1-1.70.21.61.41.21.0-1.0
Pavlov. Cond. lever contacts0.30.41.0-1.01.00.5-0.6-0.2-1.00.30.90.60.40.2-0.2
Pavlov. Cond. magazine entry number2.73.510.73.3-3.3-2.12.0-1.41.5-1.3-1.3-1.3-0.9-0.90.8
Pavlov. Cond. intertrial magazine entries0.30.61.91.4-1.4-1.00.9-0.80.1-0.8-0.0-0.3-0.2-0.20.2
Pavlov. Cond. lever-magazine prob. diff.1.21.94.9-2.22.21.2-1.10.3-1.70.41.61.41.11.0-1.0
Pavlov. Cond. response bias0.91.33.5-1.91.91.0-1.00.2-1.30.51.21.10.80.7-0.7
Time in closed arm before self-admin0.50.91.90.5-0.5-0.81.0-0.9-1.3-1.11.40.90.90.8-0.8
Time in closed arm after self-admin0.10.20.50.7-0.7-0.50.5-0.30.3-0.4-0.30.00.10.2-0.2
Time in open arm before self-admin1.21.55.90.4-0.40.1-0.31.02.40.6-2.4-1.4-1.1-0.90.8
Time in open arm after self-admin0.40.40.7-0.40.40.5-0.60.60.80.6-0.8-0.7-0.7-0.60.6
Bone: periosteal estimation0.82.05.70.0-0.0-1.10.7-2.4-1.7-0.81.71.81.61.4-1.4
Bone: periosteal perimeter0.61.32.8-0.40.4-0.60.3-1.7-1.5-0.41.51.51.41.2-1.2
Bone: post-yield work7.212.522.3-0.80.8-2.11.8-3.3-4.4-2.74.34.74.64.5-4.5
Progressive ratio test 1 active lever presses0.20.40.80.6-0.6-0.80.7-0.7-0.8-0.50.90.50.40.3-0.3
Progressive ratio test 1 breakpoint0.20.40.90.5-0.5-0.70.6-0.6-0.9-0.50.90.50.40.3-0.3
Progressive ratio test 1 inactive lever presses0.00.10.60.3-0.3-0.20.30.8-0.4-0.10.4-0.0-0.0-0.00.0
Progressive ratio test 2 active lever presses1.42.03.71.8-1.8-1.91.8-1.4-1.5-1.51.60.70.70.5-0.5
Progressive ratio test 2 breakpoint1.51.93.41.8-1.8-1.91.8-1.4-1.5-1.41.50.60.60.4-0.4
Progressive ratio test 2 inactive lever presses1.75.311.23.3-3.3-3.23.3-2.2-1.7-2.81.90.50.70.5-0.6
Incentive Sensitization - Responses0.30.91.70.1-0.1-0.70.6-1.1-1.3-0.71.31.11.11.0-1.0
Incentive Sensitization - Breakpoint0.40.91.70.4-0.4-0.90.8-1.1-1.3-0.91.31.11.00.9-0.9
Sum of active levers in priming session hrs 5-61.51.42.7-1.01.01.6-1.51.1-0.61.50.6-0.7-1.1-1.41.4
Progressive ratio1.13.26.7-1.11.1-0.50.3-1.1-2.1-1.02.02.62.52.5-2.4
Food seeking constrained by brief footshock0.10.10.3-0.20.20.3-0.30.40.50.4-0.5-0.2-0.2-0.20.2
Seeking ratio, punishment vs. effort1.33.05.91.4-1.40.1-0.00.92.40.7-2.4-2.4-2.2-2.12.0
Retroperitoneal fat weight3.716.546.46.8-6.8-5.95.6-4.40.3-4.40.1-0.50.20.1-0.3
Reaction time number correct0.20.61.2-0.60.60.9-1.10.40.71.0-0.7-0.7-0.8-0.90.9
Reaction time mean minus median0.32.25.8-2.42.41.5-1.41.3-1.70.61.51.31.00.9-0.8
Reaction time mean minus median AUC0.21.23.1-1.81.81.4-1.31.4-0.80.90.70.40.20.1-0.0
Reaction time num false alarms0.50.93.20.8-0.8-0.10.00.31.80.3-1.7-1.1-0.9-0.70.7
Reaction time num false alarms AUC0.30.72.70.1-0.10.5-0.40.81.60.7-1.6-0.9-0.7-0.60.6
Reaction time trials correct on left0.20.61.2-0.60.60.9-1.10.40.71.0-0.7-0.7-0.8-0.90.9
Reaction time trials on left0.20.81.4-0.70.71.0-1.20.50.71.1-0.8-0.7-0.9-0.91.0
Reaction time mean0.10.31.1-0.40.40.20.10.6-1.1-0.41.00.50.40.4-0.4
Reaction time mean AUC0.20.51.7-0.30.30.00.30.6-1.3-0.61.30.70.60.6-0.6
Median of all reaction times0.20.30.90.2-0.2-0.30.70.2-0.9-0.70.90.40.40.4-0.4
Reaction time omissions0.71.12.8-1.71.71.5-1.21.6-0.60.80.50.50.30.3-0.2
Reaction time false alarm rate0.30.41.40.7-0.7-0.30.30.21.20.0-1.1-0.5-0.3-0.10.1
Reaction time premature initiation rate1.93.05.3-2.02.02.3-2.31.51.82.2-1.9-0.9-1.0-0.90.9
Reaction time premature initiations1.75.39.5-2.52.53.1-3.12.22.12.9-2.2-1.3-1.6-1.51.5
Std. dev. reaction times0.30.91.9-1.41.40.9-0.71.1-1.20.31.10.70.50.4-0.4
Reaction time trials completed0.20.81.4-0.70.71.0-1.20.50.71.1-0.8-0.7-0.9-0.91.0
Reaction time trials AUC0.20.61.0-0.60.60.8-1.00.30.80.9-0.8-0.7-0.8-0.90.9
Run reversals in cocaine runway, females0.60.61.8-0.50.5-0.50.2-0.50.1-0.5-0.11.11.21.3-1.3
Run reversals in cocaine runway, males1.11.22.60.6-0.60.3-0.40.21.20.9-1.2-1.5-1.5-1.61.6
Latency to leave start box in cocaine runway1.01.32.00.4-0.4-1.01.0-1.1-1.1-1.31.11.41.41.4-1.4
Latency to leave start box in cocaine runway, F0.50.61.10.1-0.1-0.60.8-0.4-0.8-1.10.80.80.91.0-1.0
Latency to leave start box in cocaine runway, M0.40.41.00.1-0.1-0.40.2-1.0-0.6-0.40.60.90.90.8-0.8
Std. dev. time between licks in bursts0.61.13.50.2-0.20.5-0.60.41.91.0-1.9-1.1-1.1-1.01.0
Total sessions with >9 infusions1.01.22.40.1-0.1-1.00.7-1.6-1.1-0.81.11.41.41.3-1.3
Short access day 1 total inactive lever presses0.61.23.51.9-1.9-1.61.7-0.5-0.1-1.30.20.10.30.3-0.3
Short access day 10 total inactive lever presses0.10.51.70.9-0.9-0.30.61.30.7-0.4-0.7-0.5-0.4-0.20.2
Short access day 1 total infusions1.22.44.41.5-1.5-2.11.9-1.9-1.0-1.81.11.21.41.3-1.4
Short access day 10 total infusions2.94.86.60.8-0.8-2.32.0-2.3-2.3-2.32.32.52.62.5-2.5
Short access total infusions1.72.43.50.8-0.8-1.81.5-1.9-1.3-1.51.41.81.81.7-1.7
Short access day 1 locomotion1.01.73.31.6-1.6-1.81.7-1.5-0.8-1.50.90.80.90.8-0.9
Short access day 10 total locomotion0.62.33.41.2-1.2-1.91.8-1.4-1.6-1.71.71.41.41.3-1.4
Short access total locomotion1.62.44.21.4-1.4-2.01.9-1.8-1.4-1.81.51.21.31.2-1.3
One hour access (0.3 mA shock)2.93.48.93.0-3.0-2.72.6-1.9-0.7-2.00.80.10.30.1-0.2
Compulsive drug intake2.74.07.0-1.51.52.4-2.21.82.62.4-2.7-1.8-1.7-1.51.5
One hour access (shock baseline)2.15.611.13.2-3.2-3.33.3-2.3-2.0-2.92.10.91.00.8-0.8
Social response proportion0.20.30.8-0.90.90.7-0.70.3-0.50.60.50.30.20.1-0.1
Social responses0.30.40.8-0.50.50.9-0.80.80.50.9-0.5-0.5-0.6-0.60.6
Social time0.50.81.3-0.70.71.1-1.11.10.81.1-0.8-0.7-0.8-0.80.8
Soleus weight1.64.813.83.7-3.7-3.13.0-2.30.4-2.3-0.2-0.6-0.2-0.20.1
Bone: stiffness1.42.64.4-2.12.10.6-0.8-0.5-2.00.21.92.11.81.7-1.6
Tibialis anterior weight4.314.940.9-6.46.45.3-5.83.60.04.6-0.30.4-0.5-0.70.9
Time to tail flick, vehicle, before self-admin0.40.51.0-0.40.5-0.30.1-0.5-0.8-0.30.81.00.90.9-0.9
Time to tail flick, vehicle, after self-admin0.71.43.3-0.70.7-0.40.2-1.0-0.7-0.70.71.81.71.8-1.8
Time to tail flick, test, before self-admin1.92.14.11.5-1.5-2.01.9-1.8-0.4-1.90.51.01.31.3-1.4
Time to tail flick, test, after self-admin0.10.10.2-0.30.30.2-0.3-0.0-0.40.20.40.1-0.0-0.20.2
Delta time to tail flick, vehicle, before/after SA0.20.20.6-0.50.50.2-0.2-0.2-0.0-0.20.00.70.70.8-0.7
Delta time to tail flick, test, before/after SA2.73.35.4-1.51.52.3-2.22.10.62.3-0.7-1.6-1.9-2.12.1
Tibia length0.51.43.4-1.91.91.2-1.4-0.4-1.70.91.60.70.2-0.10.2
Ambulatory time before self-admin0.41.23.4-0.70.7-0.20.2-0.7-1.8-0.51.81.41.21.1-1.1
Ambulatory time after self-admin0.30.51.10.4-0.4-0.60.9-0.5-1.0-1.11.00.60.60.7-0.7
Bone: tissue strength0.10.10.2-0.00.0-0.10.2-0.2-0.5-0.20.50.40.40.4-0.4
Total heroin consumption2.22.67.2-2.72.72.4-2.11.9-0.41.70.20.50.20.2-0.1
Bone: trabecular number1.12.03.8-1.21.2-0.20.1-1.2-1.9-0.71.81.91.81.7-1.7
Bone: trabecular spacing0.40.61.60.7-0.7-0.10.20.81.30.1-1.2-1.0-0.8-0.70.7
Bone: trabecular thickness0.71.01.50.7-0.7-1.11.1-1.2-0.9-1.20.90.91.01.0-1.0
Bone: trabecular tissue density1.22.27.32.7-2.7-1.81.9-1.00.2-1.3-0.0-0.8-0.6-0.70.6
Water consumed over 24 hours0.61.22.4-1.31.31.5-1.31.60.61.2-0.7-0.7-0.7-0.60.7
Number of responses in last shaping day0.30.40.70.1-0.10.3-0.30.80.80.7-0.8-0.7-0.7-0.60.6