Hub : Genes

Stpg2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Stpg2 0.13 0.05 2.4e-15 0.13 0.11 0.11 0.09 2.3e-14 8.1e-12 1.4e-12 1.8e-10
2 Brain gene expression Stpg2 0.05 0.03 1.6e-04 0.06 0.04 0.05 0.01 6.2e-06 6.3e-05 1.9e-05 6.1e-02
3 PL gene expression Stpg2 0.09 0.04 7.7e-11 0.09 0.09 0.1 0.05 3.0e-10 2.5e-10 2.9e-11 1.5e-06
4 RMTg isoform ratio XM_017591047.3 0.16 0.09 3.7e-03 0.08 0.11 0.1 0.06 3.0e-03 6.4e-04 1.4e-03 9.3e-03
5 NAcc gene expression Stpg2 0.09 0.04 1.1e-15 0.08 0.1 0.1 0.07 1.3e-12 5.7e-15 7.4e-15 4.2e-11
6 BLA gene expression Stpg2 0.08 0.05 7.0e-03 0.03 0 0 0 6.6e-03 2.1e-01 3.3e-01 2.4e-01
7 pVTA alternative TSS XM_017591047.3 0.04 0.03 1.8e-03 0.02 0.03 0.03 0.02 1.6e-02 2.0e-03 3.9e-03 5.4e-03
8 pVTA alternative TSS NM_001100993.1 0.05 0.03 1.2e-03 0.03 0.03 0.03 0.03 2.4e-03 1.9e-03 3.8e-03 2.4e-03
9 Brain alternative TSS XM_017591047.3 0.04 0.03 4.4e-03 0 0.02 0.01 0.01 1.3e-01 4.5e-03 2.1e-02 2.5e-02
10 LHb alternative TSS XM_017591047.3 0.37 0.11 8.5e-06 0.25 0.19 0.18 0.2 1.1e-06 3.2e-05 4.2e-05 2.1e-05
11 LHb alternative TSS XM_017591047.3 0.37 0.12 1.1e-05 0.21 0.19 0.18 0.19 8.4e-06 2.3e-05 3.9e-05 3.5e-05
12 Liver alternative TSS XM_017591047.3 0.04 0.02 1.1e-03 0.03 0.02 0.03 0.02 2.0e-04 3.0e-03 2.9e-04 1.4e-03
13 Liver alternative TSS XM_017591047.3 0.07 0.04 1.1e-04 0.04 0.03 0.02 0.03 5.6e-05 5.5e-04 1.8e-03 5.2e-04
14 IC gene expression Stpg2 0.1 0.06 5.3e-03 0.04 0 -0.01 0 7.1e-03 2.2e-01 8.6e-01 2.1e-01
15 PL alternative TSS XM_017591047.3 0.06 0.03 2.0e-06 0.04 0.04 0.04 0.05 1.1e-05 1.1e-05 8.7e-05 8.7e-06
16 PL alternative TSS NM_001100993.1 0.06 0.03 3.1e-06 0.05 0.04 0.04 0.04 5.9e-06 1.4e-05 8.2e-05 1.2e-05
17 PL alternative TSS NM_001100993.1 0.06 0.03 7.8e-06 0.04 0.04 0.04 0.04 9.7e-06 8.8e-05 7.1e-05 3.3e-05
18 PL alternative TSS XM_017591047.3 0.06 0.03 4.4e-06 0.05 0.04 0.04 0.04 8.3e-06 8.6e-05 5.4e-05 5.3e-05
19 pVTA alternative TSS NM_001100993.1 0.06 0.03 9.6e-04 0.04 0.04 0.03 0.03 5.6e-04 8.3e-04 1.2e-03 4.2e-03
20 pVTA alternative TSS XM_017591047.3 0.05 0.03 1.1e-03 0.04 0.03 0.03 0.03 3.5e-04 8.7e-04 1.3e-03 2.4e-03
21 pVTA gene expression Stpg2 0.15 0.07 1.3e-09 0.13 0.13 0.14 0.14 9.8e-11 8.4e-11 3.3e-11 4.9e-11
22 NAcc alternative TSS XM_017591047.3 0.07 0.03 6.3e-12 0.08 0.08 0.08 0.08 1.3e-11 4.0e-12 4.2e-12 1.9e-12
23 NAcc alternative TSS XM_017591047.3 0.07 0.03 1.5e-10 0.07 0.07 0.06 0.07 1.8e-10 1.8e-11 7.5e-10 5.7e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.10.10.8-0.2-0.2-0.2-0.3-0.0-0.9-0.00.0-0.4-0.8-0.80.10.30.4-0.3-0.1-0.10.1-0.00.0-0.20.30.1
Area under the delay curve0.10.21.21.10.70.6-0.1-0.40.50.4-0.40.30.30.30.10.3-0.40.30.20.2-0.20.2-0.20.8-0.3-0.3
BMI with tail1.03.47.3-2.7-2.0-2.5-2.22.4-2.6-2.32.2-1.91.21.22.02.2-0.9-1.6-1.4-1.41.4-1.21.2-1.9-1.4-1.2
BMI without tail0.63.48.1-2.6-2.1-2.5-2.82.1-2.1-2.01.8-2.21.81.82.02.3-1.3-1.5-1.2-1.21.2-1.11.1-1.3-1.4-1.3
Body weight1.25.312.4-3.2-3.5-3.3-3.23.1-3.1-2.62.4-2.22.32.32.32.8-1.8-1.5-1.1-1.11.1-0.90.9-1.7-1.6-1.4
Weight adjusted by age0.30.83.91.62.01.21.4-1.40.50.8-0.70.6-0.3-0.30.50.80.9-0.3-0.5-0.50.5-0.50.50.50.50.5
Bone surface0.10.10.6-0.3-0.0-0.1-0.1-0.3-0.70.1-0.1-0.4-0.8-0.8-0.1-0.10.8-0.1-0.1-0.10.10.1-0.10.00.50.4
Bone volume0.20.41.9-0.6-0.2-0.1-0.3-0.4-0.40.3-0.4-0.7-1.4-1.4-0.5-0.41.10.00.10.1-0.10.3-0.3-0.00.90.8
Breakpoint value in progressive ratio session0.10.20.5-0.4-0.6-0.40.10.6-0.7-0.60.70.30.50.50.60.2-0.5-0.3-0.2-0.20.2-0.30.3-0.4-0.4-0.2
Number of licking bursts0.72.34.3-1.0-0.0-1.30.71.5-1.3-1.81.9-0.61.11.11.21.3-0.6-1.9-2.1-2.12.1-2.12.1-2.0-1.3-1.1
Context. condit. distance diff. score0.20.21.00.1-0.30.10.80.4-0.7-0.60.61.00.50.50.60.5-0.6-0.2-0.1-0.10.1-0.10.10.0-0.5-0.4
Locomotion velocity, session 10.40.41.7-1.3-0.7-0.8-0.90.80.9-0.60.6-0.90.30.30.30.3-0.4-0.2-0.4-0.40.4-0.50.5-0.9-0.3-0.3
Locomotion distance, session 10.30.41.7-0.5-0.4-0.3-0.40.81.1-0.60.60.01.11.10.50.5-1.3-0.1-0.4-0.40.4-0.50.5-0.3-0.9-0.8
Locomotion velocity, session 20.10.20.80.20.80.20.0-0.10.90.00.0-0.20.50.50.20.1-0.2-0.2-0.5-0.50.5-0.50.5-0.4-0.3-0.4
Locomotion distance, session 20.50.77.70.80.61.20.5-0.62.80.8-0.80.90.20.2-0.4-0.5-0.30.90.50.5-0.50.5-0.50.80.00.2
Locomotion velocity, session 30.40.51.2-1.0-0.9-0.10.10.10.90.2-0.20.1-1.1-1.1-0.8-0.80.80.70.60.6-0.60.7-0.7-0.00.80.9
Locomotion distance, session 30.10.10.6-0.6-0.8-0.3-0.30.60.3-0.40.4-0.2-0.4-0.4-0.0-0.10.0-0.0-0.0-0.00.00.1-0.1-0.2-0.1-0.2
Stereotopy head waving bouts, day 30.20.21.0-1.0-0.9-0.6-0.70.70.7-0.30.2-0.80.50.5-0.5-0.5-0.30.1-0.0-0.00.0-0.10.1-0.4-0.1-0.0
Stereotopy head waving duration, day 30.70.93.0-1.7-1.7-1.5-1.01.5-0.1-1.01.0-1.11.01.0-0.0-0.1-0.8-0.3-0.4-0.40.4-0.50.5-1.1-0.5-0.3
Locomotion velocity, session 71.11.22.9-0.80.1-0.80.10.9-0.4-1.21.3-0.9-0.1-0.11.21.1-0.2-1.4-1.7-1.71.7-1.61.6-1.5-0.9-0.8
Locomotion distance, session 70.70.81.7-0.2-0.1-0.10.60.9-0.4-1.11.20.50.80.81.31.2-1.2-0.8-1.1-1.11.1-1.01.0-0.5-1.3-1.1
Stereotopy head waving bouts, day 71.82.14.70.30.00.90.0-1.02.21.6-1.60.4-1.1-1.1-2.1-2.11.31.81.71.7-1.71.8-1.81.21.61.4
Stereotopy head waving duration, day 72.93.66.10.60.51.40.7-1.72.42.1-2.10.7-2.1-2.1-2.5-2.52.12.01.91.9-1.92.0-2.01.62.32.2
Locomotion velocity, session 80.10.20.40.20.50.10.10.10.5-0.20.20.00.60.60.30.2-0.6-0.4-0.5-0.50.5-0.50.5-0.2-0.6-0.6
Locomotion distance, session 80.30.42.10.30.00.60.80.30.9-0.20.31.40.70.70.70.6-1.10.20.00.0-0.00.0-0.00.5-0.7-0.4
Degree of sensitization distance1.31.43.40.40.3-0.10.60.8-1.1-1.11.20.61.81.81.51.4-1.8-1.1-1.2-1.21.2-1.31.3-0.5-1.7-1.4
Degree of sensitization stereotypy2.73.04.80.80.21.30.2-1.52.11.9-2.00.7-1.6-1.6-2.1-2.21.62.02.02.0-2.02.1-2.11.81.91.7
Conditioned locomotion1.92.24.11.31.31.50.5-2.01.32.0-2.00.5-1.8-1.8-1.5-1.51.71.11.21.2-1.21.2-1.21.61.91.5
Cocaine response after cond. corrected0.30.41.6-0.11.00.20.1-1.00.50.7-0.7-0.3-1.0-1.0-0.4-0.51.30.00.10.1-0.1-0.00.00.10.90.8
Cocaine response after cond. not corrected0.20.41.80.61.30.5-0.1-1.10.80.8-0.9-0.5-0.6-0.6-0.4-0.30.8-0.0-0.1-0.10.1-0.20.20.30.50.2
Cocaine response before conditioning0.30.31.41.20.20.4-0.60.10.20.1-0.1-0.20.90.90.30.5-1.00.0-0.2-0.20.2-0.10.10.4-0.9-1.0
Saline control response1.72.45.01.70.42.00.9-0.92.21.6-1.61.7-0.9-0.9-1.9-1.80.02.11.71.7-1.71.7-1.72.20.70.8
Bone: connectivity density0.10.20.91.00.60.60.7-0.6-0.80.3-0.30.7-0.3-0.30.10.20.20.00.10.1-0.10.2-0.20.40.30.1
Bone: cortical apparent density0.40.61.2-0.5-0.8-0.8-0.61.1-0.4-0.90.9-0.50.80.80.70.6-1.0-0.7-0.7-0.70.7-0.70.7-0.5-0.9-0.9
Bone: cortical area1.32.26.1-2.5-1.8-2.2-1.81.7-2.1-1.61.5-2.20.40.41.01.1-0.6-1.5-1.2-1.21.2-1.21.2-1.6-0.6-0.6
Bone: cortical porosity0.10.10.3-0.1-0.0-0.0-0.6-0.10.40.3-0.3-0.30.20.2-0.3-0.1-0.10.30.20.2-0.20.3-0.30.4-0.10.0
Bone: cortical porosity0.00.00.3-0.30.0-0.1-0.5-0.10.20.2-0.2-0.20.10.1-0.00.10.00.20.10.1-0.10.2-0.20.4-0.00.2
Bone: cortical thickness1.52.56.6-2.6-2.1-2.4-2.21.9-2.4-1.71.6-2.30.40.41.11.1-0.8-1.5-1.1-1.11.1-1.11.1-1.6-0.7-0.8
Bone: cortical thickness0.60.73.7-0.5-0.6-0.9-1.90.6-1.3-0.50.3-1.70.10.10.70.7-0.8-1.0-0.7-0.70.7-0.60.6-0.2-0.6-0.9
Bone: cortical tissue density0.40.61.4-0.5-0.9-0.8-0.61.2-0.4-1.00.9-0.40.90.90.70.6-1.2-0.7-0.7-0.70.7-0.70.7-0.5-1.0-1.0
Condit. Reinf. active minus inactive responses0.91.02.3-0.8-1.3-1.20.01.4-0.1-1.31.4-0.11.51.51.01.0-1.0-0.7-0.8-0.80.8-0.90.9-1.3-0.8-0.6
Condit. Reinf. active-inactive response ratio2.83.05.5-1.9-2.0-2.2-0.52.3-1.3-2.32.3-1.01.71.71.81.8-1.1-1.6-1.6-1.61.6-1.71.7-2.4-1.3-0.8
Condit. Reinf. active responses0.20.31.60.9-0.00.61.0-0.31.30.3-0.31.00.30.3-0.1-0.1-0.00.50.30.3-0.30.3-0.30.40.30.4
Condit. Reinf. inactive responses2.93.76.22.21.42.41.1-2.32.22.4-2.41.6-1.7-1.7-1.9-1.81.42.01.81.8-1.81.9-1.92.51.71.5
Incentive salience index mean0.60.81.7-0.6-0.9-1.0-0.11.1-0.4-1.11.1-0.21.31.30.90.9-0.8-0.8-0.8-0.80.8-0.80.8-1.1-0.7-0.6
Condit. Reinf. lever presses0.00.00.10.1-0.00.00.2-0.2-0.40.1-0.10.1-0.1-0.1-0.2-0.10.3-0.10.00.0-0.00.1-0.1-0.00.30.2
Condit. Reinf. active minus inactive responses0.71.03.3-0.7-0.3-1.0-0.91.0-1.8-1.01.0-1.20.80.80.50.8-0.7-1.3-1.1-1.11.1-1.11.1-0.9-0.9-1.1
Condit. Reinf. active-inactive response ratio0.91.54.6-1.5-0.6-1.4-0.31.3-2.1-1.51.5-1.00.50.50.81.1-0.3-1.6-1.3-1.31.3-1.41.4-1.5-0.7-0.8
Condit. Reinf. active responses1.11.63.2-0.2-0.5-1.1-1.41.3-1.7-1.11.1-1.51.61.60.81.0-1.5-1.4-1.3-1.31.3-1.31.3-0.8-1.5-1.8
Condit. Reinf. inactive responses0.40.62.40.7-0.2-0.2-1.10.6-0.2-0.30.2-0.51.41.40.60.5-1.6-0.2-0.3-0.30.3-0.20.20.3-1.2-1.3
Condit. Reinf. lever presses1.01.44.10.6-0.6-0.6-0.91.1-1.5-0.90.9-0.42.02.01.11.2-2.0-1.0-0.8-0.80.8-0.80.8-0.3-1.7-1.8
Condit. Reinf. lever reinforcers received1.11.63.3-0.0-0.6-1.0-1.41.3-1.6-1.11.0-1.41.61.60.81.0-1.6-1.3-1.2-1.21.2-1.11.1-0.7-1.6-1.8
Conditioned reinforcement - actives0.83.15.70.70.51.51.9-1.41.41.7-1.72.4-1.4-1.4-1.7-2.11.32.02.12.1-2.12.0-2.01.81.82.1
Conditioned reinforcement - inactives0.41.02.60.60.30.81.0-0.81.60.9-0.91.2-0.7-0.7-1.0-1.20.71.31.11.1-1.11.1-1.10.61.01.0
Conditioned locomotion2.13.07.51.81.42.02.2-1.90.81.9-1.92.7-0.9-0.9-1.5-1.90.81.81.91.9-1.91.8-1.82.01.41.6
Patch foraging indifference point 0 sec0.20.73.81.61.21.21.7-0.60.40.4-0.32.00.20.20.3-0.3-0.60.30.30.3-0.30.3-0.31.1-0.3-0.1
Patch foraging indifference point AUC0.51.32.2-1.4-1.3-1.5-0.81.4-1.4-1.41.4-1.11.11.10.70.4-0.8-1.1-1.0-1.01.0-1.01.0-1.4-0.7-0.9
Delay disc. indifference point, 0s delay0.10.10.60.30.50.20.8-0.3-0.30.1-0.00.4-0.1-0.1-0.3-0.30.50.10.10.1-0.10.1-0.10.00.30.2
Delay disc. indifference point, 16s delay0.10.10.5-0.1-0.2-0.2-0.40.40.2-0.30.30.00.30.30.30.1-0.7-0.1-0.0-0.00.0-0.00.0-0.1-0.5-0.3
Delay disc. indifference point, 2s delay0.91.02.41.51.01.10.1-1.40.11.5-1.50.5-0.3-0.3-0.8-0.50.80.91.01.0-1.01.0-1.01.50.80.7
Delay disc. indifference point, 24s delay0.50.92.31.51.31.40.4-1.40.71.3-1.30.8-0.5-0.5-0.6-0.20.50.90.80.8-0.80.8-0.81.50.50.4
Delay disc. indifference point, 4s delay0.40.41.50.80.90.10.1-0.1-0.4-0.30.3-0.10.10.11.21.2-0.4-0.8-0.9-0.90.9-0.90.9-0.2-0.6-0.6
Delay disc. indifference point, 8s delay0.50.83.21.20.41.1-0.2-0.71.81.0-1.00.70.10.1-0.6-0.4-0.31.21.01.0-1.01.0-1.01.60.00.1
Indifference point function ln k0.20.52.01.41.21.21.1-0.81.10.6-0.61.2-0.3-0.30.10.3-0.00.30.10.1-0.10.1-0.11.0-0.10.2
Indifference point function log k0.20.52.01.41.21.21.1-0.81.10.6-0.61.2-0.3-0.30.10.3-0.00.30.10.1-0.10.1-0.11.0-0.10.2
Patch foraging total patch changes 0 sec0.20.74.01.61.21.21.7-0.60.30.4-0.22.00.30.30.4-0.2-0.70.20.20.2-0.20.2-0.21.1-0.4-0.2
Patch foraging total patch changes 12 sec0.30.41.00.10.1-0.20.30.5-0.9-0.70.70.41.01.00.90.5-1.0-0.6-0.5-0.50.5-0.40.4-0.3-0.8-0.8
Patch foraging total patch changes 18 sec0.20.51.30.10.60.01.10.3-0.9-0.80.91.00.70.71.10.7-0.6-0.8-0.8-0.80.8-0.60.6-0.2-0.7-0.5
Patch foraging total patch changes 24 sec0.00.11.00.40.50.31.0-0.2-0.2-0.00.11.00.10.10.4-0.3-0.1-0.1-0.1-0.10.1-0.10.10.0-0.00.2
Patch foraging total patch changes 6 sec1.11.85.2-0.2-0.0-0.60.51.3-2.3-1.61.70.71.81.81.91.2-1.9-1.3-1.1-1.11.1-1.11.1-0.7-1.7-1.5
Patch foraging time to switch 0 sec0.20.71.7-0.5-0.30.1-0.6-0.60.60.7-0.8-0.2-0.9-0.9-0.8-0.41.00.91.11.1-1.11.3-1.30.30.90.9
Patch foraging water rate 0 sec0.10.41.10.40.30.10.50.4-1.1-0.50.60.30.50.50.70.4-0.7-0.7-0.7-0.70.7-0.80.80.2-0.7-0.6
Patch foraging water rate 12 sec0.10.51.30.2-0.4-0.5-0.50.9-0.4-0.70.7-0.40.70.70.80.7-0.9-0.7-0.7-0.70.7-0.70.7-0.2-1.1-0.8
Patch foraging water rate 18 sec1.22.75.8-0.20.2-1.3-0.21.1-2.4-1.51.6-1.21.21.21.81.4-1.1-2.3-2.2-2.22.2-2.42.4-1.7-1.4-1.3
Patch foraging water rate 24 sec1.42.04.1-0.10.4-0.80.21.0-1.3-1.41.5-0.71.21.21.61.8-1.0-1.8-2.0-2.02.0-1.91.9-1.1-1.6-1.3
Patch foraging water rate 6 sec2.33.45.8-1.3-0.6-1.5-0.72.0-0.9-2.22.3-1.11.51.52.21.8-1.8-2.1-2.4-2.42.4-2.32.3-1.7-2.1-1.8
Seeking ratio, delayed vs. immediate footshock0.60.92.21.50.81.40.0-1.30.61.3-1.30.90.00.0-0.30.00.01.11.11.1-1.11.1-1.11.40.40.3
Distance traveled before self-admin1.22.77.0-0.8-0.00.71.1-1.30.81.3-1.20.8-2.5-2.5-1.6-1.82.61.51.71.7-1.71.6-1.60.52.42.6
Distance traveled after self-admin0.10.10.5-0.1-0.2-0.00.7-0.10.2-0.10.10.3-0.5-0.50.00.10.70.20.10.1-0.10.1-0.1-0.50.30.6
Extensor digitorum longus weight2.28.746.1-6.8-6.2-4.8-5.33.9-2.1-2.72.4-4.20.60.60.91.1-0.2-0.40.00.0-0.0-0.00.0-3.10.10.2
Bone: elastic displacement0.50.62.3-1.5-0.8-1.2-0.70.8-1.0-0.80.8-1.1-0.2-0.20.50.70.3-0.8-0.6-0.60.6-0.60.6-0.90.10.1
Bone: elastic work2.63.36.0-2.3-1.6-2.4-2.02.1-2.3-2.12.0-2.50.80.81.51.7-1.0-2.2-1.8-1.81.8-1.81.8-1.9-1.2-1.3
Bone: endosteal estimation0.00.10.3-0.50.0-0.10.6-0.00.3-0.10.20.10.00.0-0.2-0.10.4-0.0-0.1-0.10.1-0.20.2-0.50.30.3
Bone: endosteal perimeter0.10.21.0-1.0-0.9-0.6-0.30.60.2-0.40.4-0.60.10.1-0.4-0.30.2-0.0-0.1-0.10.1-0.00.0-0.60.10.1
Epididymis fat weight0.31.73.3-1.6-1.6-1.6-1.51.8-1.7-1.61.6-1.40.80.81.11.4-1.1-1.1-1.0-1.01.0-1.01.0-1.4-1.1-1.2
Delta time in closed arm before/after self-admin0.10.10.4-0.4-0.4-0.30.30.40.6-0.30.30.10.30.3-0.2-0.2-0.10.1-0.1-0.10.10.1-0.1-0.2-0.2-0.0
Delta time in open arm before/after self-admin2.32.74.30.80.21.60.7-1.51.51.8-1.91.4-1.3-1.3-1.8-1.81.12.02.12.1-2.12.0-2.01.81.81.7
Diff in mean of infusions in LGA sessions0.91.63.20.30.9-0.50.40.5-0.9-1.21.3-0.41.01.01.61.1-1.0-1.7-1.8-1.81.8-1.71.7-1.4-1.4-1.5
Delay discount exponential model param0.20.21.6-1.3-0.8-0.70.10.5-0.5-0.50.5-0.4-0.2-0.2-0.2-0.40.4-0.3-0.2-0.20.2-0.20.2-0.90.30.3
Extinction: sum of active levers before priming1.31.93.3-1.8-1.5-1.8-1.61.4-1.4-1.61.6-1.41.31.31.81.3-1.0-1.3-1.2-1.21.2-1.31.3-1.7-0.9-0.9
Active lever presses in extinction session 60.60.63.61.91.31.01.3-0.8-0.00.5-0.41.50.60.60.3-0.0-0.80.0-0.0-0.00.0-0.10.10.5-0.3-0.3
Bone: final force0.71.11.7-0.8-0.7-1.1-0.31.2-1.2-1.31.3-0.70.90.91.01.0-1.1-1.3-1.2-1.21.2-1.21.2-1.1-1.1-1.0
Bone: final moment0.91.52.2-0.7-0.6-1.2-0.41.2-1.3-1.41.4-0.91.01.01.11.1-1.2-1.5-1.4-1.41.4-1.51.5-1.2-1.2-1.1
Food consumed during 24 hour testing period0.50.92.7-0.9-0.0-0.7-0.40.7-0.6-1.01.0-0.70.40.41.61.6-0.2-1.1-1.3-1.31.3-1.21.2-0.9-0.7-0.5
Glucose1.11.73.9-1.3-0.4-1.4-1.11.1-1.0-1.41.4-1.30.70.71.82.0-0.7-1.5-1.5-1.51.5-1.51.5-1.5-0.9-0.9
Heart weight0.50.73.1-0.6-1.8-1.2-1.51.4-1.1-0.80.7-1.20.90.9-0.10.1-0.8-0.4-0.2-0.20.2-0.20.2-0.5-0.8-0.8
Delay discount hyperbolic model param0.30.32.1-1.5-1.0-0.9-0.10.8-0.5-0.70.7-0.5-0.0-0.0-0.1-0.30.2-0.3-0.3-0.30.3-0.30.3-1.00.20.2
Intermittent access intake day 1-15 change0.31.45.10.01.20.70.8-1.60.61.2-1.10.4-1.9-1.9-0.5-1.02.20.80.80.8-0.80.8-0.80.31.81.7
Intermittent access intake escalation0.21.34.8-0.01.30.71.0-1.50.31.1-1.00.5-1.9-1.9-0.4-0.82.20.70.80.8-0.80.8-0.80.11.81.7
Intermittent access intake escalation 20.30.42.4-0.80.6-0.10.2-0.6-0.60.2-0.1-0.3-1.2-1.20.3-0.11.6-0.10.10.1-0.10.1-0.1-0.61.11.0
Intermitt. access day 1 inactive lever presses0.00.41.50.3-0.40.0-0.60.50.6-0.30.30.11.21.20.20.4-1.2-0.0-0.2-0.20.2-0.20.20.1-1.0-1.0
Intermitt. access day 15 inactive lever presses0.00.20.7-0.4-0.8-0.5-0.80.80.4-0.40.4-0.60.30.3-0.2-0.3-0.50.1-0.0-0.00.0-0.10.1-0.5-0.4-0.4
Intermitt. access escalation Index0.20.51.00.60.00.4-0.2-0.60.60.9-1.00.20.10.1-0.9-0.70.30.91.01.0-1.01.0-1.00.50.70.5
Intermittent access day 1 total infusions0.51.42.1-0.8-0.7-1.2-0.51.2-0.9-1.31.4-0.81.11.11.41.4-1.3-1.2-1.3-1.31.3-1.41.4-1.4-1.2-1.0
Intermittent access day 15 total infusions0.30.72.2-1.0-0.1-1.1-0.20.6-1.0-0.91.0-0.70.00.01.31.00.0-1.0-0.9-0.90.9-1.01.0-1.5-0.2-0.2
Intermittent access terminal intake (last 3 days)0.50.92.2-0.9-0.2-1.0-0.20.7-1.0-1.11.1-0.60.40.41.51.0-0.4-1.1-1.1-1.11.1-1.11.1-1.4-0.5-0.4
Intermittent access total infusions1.61.83.2-1.1-0.8-1.6-0.61.4-1.2-1.61.7-0.91.11.11.81.6-1.2-1.4-1.4-1.41.4-1.51.5-1.8-1.2-1.0
Intermittent access day 1 locomotion0.20.30.60.3-0.3-0.30.20.4-0.7-0.40.50.00.50.50.70.6-0.8-0.6-0.6-0.60.6-0.70.7-0.3-0.6-0.4
Intermittent access day 15 total locomotion0.20.62.5-0.01.10.21.2-1.0-0.60.4-0.30.3-1.6-1.60.2-0.31.6-0.10.00.0-0.0-0.10.1-0.21.21.2
Intermittent access total locomotion0.20.20.9-0.30.1-0.40.40.0-1.0-0.40.4-0.1-0.4-0.40.70.40.3-0.6-0.5-0.50.5-0.60.6-0.80.10.3
Intermittent access standard deviation0.10.41.6-1.3-0.7-1.2-1.10.5-1.1-0.50.4-1.0-0.2-0.20.40.30.2-0.5-0.2-0.20.2-0.30.3-0.90.10.3
Left kidney weight0.22.08.1-2.3-2.8-2.1-2.31.8-1.7-1.41.2-1.31.51.51.41.4-1.0-0.6-0.3-0.30.3-0.20.2-0.8-0.6-0.4
Right kidney weight0.32.29.4-2.1-3.1-2.1-2.42.0-2.0-1.41.3-1.61.51.51.31.6-1.3-0.7-0.4-0.40.4-0.40.4-0.8-0.9-0.7
Cocaine induced anxiety0.10.20.30.30.2-0.10.50.4-0.1-0.50.5-0.10.20.2-0.0-0.1-0.1-0.5-0.6-0.60.6-0.60.6-0.3-0.4-0.5
Post-drug Anxiety0.10.10.40.40.4-0.00.70.00.2-0.10.2-0.1-0.2-0.2-0.3-0.60.5-0.3-0.4-0.40.4-0.40.4-0.50.1-0.1
Baseline Anxiety0.10.10.5-0.7-0.4-0.4-0.50.1-0.2-0.20.1-0.4-0.6-0.60.30.00.5-0.10.00.0-0.00.0-0.0-0.50.30.3
Tail length0.10.73.4-1.1-1.9-1.0-1.60.9-0.6-0.40.2-0.71.21.20.10.7-0.90.10.50.5-0.50.4-0.40.0-0.1-0.2
Length with tail0.41.96.4-1.6-2.5-1.9-2.21.7-1.7-1.21.0-1.12.02.01.11.6-1.7-0.6-0.1-0.10.1-0.10.1-0.5-0.9-0.8
Length without tail0.10.51.8-0.1-1.3-0.8-0.61.0-1.2-0.60.5-0.11.31.30.20.3-1.3-0.2-0.1-0.10.1-0.00.0-0.3-0.6-0.7
Times rat made contact with spout1.51.83.5-0.60.9-1.0-0.60.5-1.2-1.21.2-1.30.70.71.81.7-0.4-1.9-1.9-1.91.9-1.81.8-1.3-1.0-1.1
Lifetime Intake0.70.81.6-1.0-0.7-1.1-0.31.0-0.7-1.11.2-0.30.80.81.31.2-0.9-0.8-0.9-0.90.9-0.90.9-1.3-0.8-0.6
Liver weight, left0.10.10.5-0.3-0.3-0.2-0.30.1-0.20.1-0.2-0.3-0.2-0.2-0.4-0.70.40.30.20.2-0.20.3-0.30.20.40.3
Liver weight, right0.40.82.70.10.4-0.80.40.3-1.6-0.60.6-0.60.40.40.70.50.1-1.4-1.3-1.31.3-1.31.3-0.8-0.2-0.2
Locomotor activity0.30.41.40.10.1-0.3-0.60.60.4-0.50.5-0.70.70.70.50.8-0.9-0.6-0.7-0.70.7-0.90.9-0.2-0.9-1.2
Locomotor testing distance0.40.93.00.60.0-0.3-0.90.80.3-0.60.6-0.61.31.30.91.2-1.6-0.8-0.9-0.90.9-0.80.8-0.1-1.4-1.7
Locomotor testing rearing2.07.415.20.91.0-1.3-0.81.8-1.6-2.42.5-1.13.43.43.33.3-3.3-3.1-3.2-3.23.2-2.92.9-1.7-3.8-3.9
Locomotion in novel chamber0.20.31.20.91.10.8-0.1-0.7-0.10.6-0.60.30.30.3-0.2-0.4-0.40.20.30.3-0.30.3-0.30.8-0.2-0.6
Locomotion in novel chamber post-restriction0.10.31.4-0.0-0.7-0.0-1.10.41.20.1-0.2-0.70.10.1-0.6-0.7-0.80.50.30.3-0.30.5-0.50.2-0.4-0.6
Fecal boli incidents, locomotor time 10.10.41.50.50.90.60.2-0.71.20.8-0.7-0.2-0.8-0.8-1.0-0.70.80.40.10.1-0.10.1-0.10.10.50.4
Change in fecal boli incidents, locomotor task1.31.43.3-0.0-0.3-0.7-0.70.9-0.5-1.11.1-0.41.81.81.61.5-1.6-1.2-1.2-1.21.2-1.11.1-0.6-1.5-1.6
Time >=10cm from walls, locomotor time 11.72.14.3-1.0-1.4-1.3-0.91.9-1.4-1.81.8-0.72.12.11.11.1-2.0-1.2-1.0-1.01.0-1.01.0-1.2-2.0-1.9
Bouts of movement, locomotor time 10.20.21.10.20.50.00.1-0.3-1.1-0.10.1-0.3-0.3-0.30.40.80.6-0.7-0.5-0.50.5-0.50.5-0.20.0-0.0
Total resting periods, locomotor time 10.30.30.90.30.70.00.2-0.3-0.9-0.10.2-0.3-0.2-0.20.50.90.6-0.8-0.7-0.70.7-0.70.7-0.4-0.1-0.1
Rest time, locomotor task time 10.40.71.51.21.11.10.6-1.20.21.1-1.10.5-0.7-0.7-0.9-0.51.00.50.60.6-0.60.6-0.60.90.80.5
Distance moved, locomotor task time 10.51.43.6-1.2-1.2-1.4-1.11.7-0.0-1.41.4-0.81.91.90.80.6-1.8-0.5-0.6-0.60.6-0.70.7-0.9-1.5-1.3
Vertical activity count, locomotor time 10.10.61.5-0.8-1.0-0.8-0.91.1-0.1-0.90.8-0.51.21.20.50.0-1.2-0.3-0.3-0.30.3-0.20.2-0.6-0.9-0.9
Time >=10cm from walls, locomotor time 20.10.21.6-1.1-1.3-0.7-0.80.80.2-0.40.4-0.40.40.4-0.10.1-0.10.20.10.1-0.10.3-0.30.1-0.10.0
Bouts of movement, locomotor time 20.31.02.01.21.11.40.9-1.20.61.1-1.11.1-1.1-1.1-0.8-0.70.60.70.80.8-0.81.0-1.01.40.70.7
Total resting periods, locomotor time 20.21.02.41.41.41.61.0-1.30.51.1-1.11.2-1.1-1.1-0.6-0.60.50.70.70.7-0.70.9-0.91.40.50.5
Rest time, locomotor task time 20.20.32.11.50.60.8-0.3-0.7-0.20.7-0.80.30.20.2-0.10.0-0.40.50.70.7-0.70.5-0.50.5-0.1-0.4
Distance moved, locomotor task time 20.10.11.0-1.0-0.6-0.50.20.60.4-0.50.50.10.50.5-0.2-0.4-0.20.00.00.0-0.0-0.00.0-0.1-0.00.1
Vertical activity count, locomotor time 20.10.31.3-0.9-1.2-0.3-0.40.30.20.0-0.10.00.10.1-0.5-0.70.20.50.60.6-0.60.7-0.70.60.40.4
Light reinforcement 10.31.33.5-0.4-1.1-1.1-0.81.5-0.4-1.31.3-0.41.61.61.31.1-1.9-0.9-0.9-0.90.9-0.80.8-0.7-1.4-1.3
Light reinforcement 20.00.10.40.60.60.30.0-0.4-0.00.2-0.2-0.1-0.2-0.20.30.10.0-0.3-0.2-0.20.2-0.20.2-0.1-0.0-0.1
Bone: marrow area0.00.10.4-0.30.2-0.00.7-0.10.3-0.10.20.20.00.0-0.2-0.10.4-0.0-0.1-0.10.1-0.20.2-0.40.30.4
Bone: maximum diameter0.20.31.0-0.9-0.5-0.9-0.60.6-0.8-0.60.6-1.00.30.30.20.3-0.1-0.7-0.6-0.60.6-0.50.5-0.7-0.1-0.2
Bone: maximum force0.40.92.1-0.9-0.6-1.0-0.11.0-1.5-1.11.1-0.70.70.70.50.5-0.8-1.2-1.1-1.11.1-1.11.1-1.0-0.8-0.7
Bone: maximum moment0.61.22.3-0.8-0.4-1.0-0.21.0-1.5-1.11.2-0.90.90.90.70.7-0.9-1.4-1.4-1.41.4-1.41.4-1.1-0.9-0.9
Mean time between licks in bursts0.00.20.7-0.5-0.3-0.50.70.20.2-0.40.40.1-0.2-0.20.00.20.7-0.1-0.2-0.20.2-0.20.2-0.80.40.6
Mean num. licks in bursts0.20.41.40.30.30.3-1.2-0.80.40.8-0.9-0.4-0.3-0.3-0.1-0.20.30.70.80.8-0.80.8-0.80.80.50.2
Cd content in liver2.52.85.2-1.6-1.3-1.9-0.72.3-1.8-2.22.2-0.62.02.01.61.5-1.9-1.5-1.3-1.31.3-1.31.3-1.9-1.8-1.7
Co content in liver0.40.53.4-1.8-1.2-0.9-0.50.9-0.3-0.80.8-0.5-0.4-0.40.81.10.2-0.3-0.3-0.30.3-0.30.3-0.4-0.00.4
Cu content in liver0.70.93.51.81.90.91.4-0.7-0.70.10.11.20.90.90.90.9-0.8-0.8-0.7-0.70.7-0.70.70.2-0.8-0.7
Fe content in liver2.43.04.71.60.11.60.4-1.61.12.0-2.11.2-1.3-1.3-2.1-2.11.21.92.12.1-2.12.2-2.22.21.61.5
K content in liver0.30.21.41.01.20.50.5-0.5-0.00.2-0.1-0.0-0.2-0.20.20.30.0-0.5-0.6-0.60.6-0.60.6-0.2-0.2-0.3
Mg content in liver0.30.40.80.50.80.20.60.1-0.1-0.40.50.10.40.40.50.6-0.5-0.7-0.8-0.80.8-0.90.9-0.5-0.7-0.7
Mn content in liver0.40.51.1-1.0-0.9-0.9-0.90.9-0.5-0.80.8-1.00.30.30.40.8-0.2-0.5-0.5-0.50.5-0.60.6-0.9-0.5-0.5
Na content in liver0.20.21.41.21.10.50.3-0.5-0.00.3-0.3-0.1-0.1-0.1-0.2-0.1-0.2-0.5-0.5-0.50.5-0.40.4-0.0-0.3-0.5
Rb content in liver1.11.33.91.72.01.61.8-1.70.41.4-1.31.5-0.9-0.9-0.7-0.70.90.60.60.6-0.60.6-0.61.31.01.0
Se content in liver0.81.02.0-0.1-0.50.7-0.1-0.70.40.9-1.00.5-1.4-1.4-0.8-0.61.21.11.21.2-1.21.2-1.20.91.21.2
Sr content in liver0.50.42.8-0.6-1.2-0.5-1.70.60.1-0.30.2-1.00.80.80.40.6-0.9-0.0-0.1-0.10.1-0.10.1-0.1-0.6-0.8
Zn content in liver4.45.117.33.74.21.63.0-0.8-1.9-0.60.91.91.81.82.02.0-2.2-2.3-2.4-2.42.4-2.42.4-0.2-2.4-2.6
Bone: minimum diameter0.91.77.1-2.7-2.2-2.2-1.51.8-0.9-1.51.5-1.50.90.90.80.8-0.7-0.7-0.7-0.70.7-0.60.6-1.7-0.6-0.4
Time in familiar zone, hab. session 10.20.20.6-0.00.10.40.4-0.30.10.4-0.40.4-0.3-0.3-0.7-0.80.30.50.50.5-0.50.6-0.60.70.30.4
Time in novel zone, hab. session 10.10.20.60.20.1-0.2-0.60.1-0.1-0.20.2-0.8-0.0-0.00.30.3-0.2-0.5-0.5-0.50.5-0.60.6-0.5-0.3-0.5
Total zone transitions, hab. session 10.91.23.1-0.6-0.30.70.5-0.51.80.9-0.81.2-0.7-0.7-0.8-0.80.81.71.51.5-1.51.5-1.50.71.21.4
Total locomotion distance, hab. session 10.10.20.70.30.60.50.6-0.20.80.4-0.30.90.50.5-0.3-0.5-0.20.50.30.3-0.30.3-0.30.20.10.1
Locomotion velocity, hab. session 10.10.10.70.00.30.30.5-0.00.50.1-0.10.80.80.80.0-0.1-0.50.30.20.2-0.20.1-0.10.0-0.1-0.1
Time in familiar zone, hab. session 20.50.62.5-0.8-0.6-1.0-1.60.8-1.0-0.70.6-1.50.40.40.40.5-0.5-0.8-0.6-0.60.6-0.60.6-0.5-0.7-0.8
Time in novel zone, hab. session 20.40.52.61.30.51.01.4-0.60.80.5-0.41.60.00.0-0.2-0.2-0.10.70.40.4-0.40.5-0.50.60.20.3
Total zone transitions, hab. session 20.30.41.3-0.8-1.0-0.0-0.30.41.20.1-0.10.70.50.5-0.2-0.1-0.41.00.90.9-0.90.9-0.90.40.20.4
Total locomotion distance, hab. session 20.60.83.1-0.4-0.8-0.7-0.81.00.1-0.70.7-0.11.81.80.70.7-1.7-0.3-0.3-0.30.3-0.40.4-0.4-1.1-1.1
Locomotion velocity, hab. session 20.40.52.6-0.3-0.5-0.4-0.50.70.3-0.50.50.11.61.60.50.5-1.6-0.2-0.2-0.20.2-0.20.2-0.2-0.9-1.0
Novel to familiar place preference ratio0.40.61.4-0.4-0.4-0.6-0.20.7-0.3-0.90.90.01.11.11.21.1-0.9-0.6-0.7-0.70.7-0.60.6-0.7-0.9-0.8
Novelty place preference0.70.92.2-0.3-0.3-0.7-0.40.8-0.4-1.01.0-0.11.41.41.51.4-1.1-0.8-0.9-0.90.9-0.80.8-0.8-1.1-1.0
Time in novel zone, NPP test0.81.02.4-0.4-0.4-0.8-0.50.9-0.5-1.11.1-0.21.51.51.61.5-1.2-0.8-0.9-0.90.9-0.90.9-0.9-1.2-1.1
Total zone transitions, NPP test0.20.31.5-1.2-1.2-0.5-0.80.80.8-0.40.30.00.60.60.20.2-0.60.40.40.4-0.40.4-0.4-0.1-0.2-0.0
Total locomotion distance, NPP test0.60.92.9-0.6-0.8-0.9-0.61.2-0.4-1.01.0-0.11.71.70.90.8-1.6-0.7-0.5-0.50.5-0.60.6-0.7-1.1-1.1
Locomotion velocity, NPP test1.01.43.5-0.9-0.9-1.2-0.91.5-0.5-1.31.3-0.51.91.91.11.1-1.8-1.0-0.8-0.80.8-0.90.9-1.0-1.4-1.4
Intraocular pressure0.30.41.2-0.5-0.7-0.1-1.1-0.00.30.5-0.6-0.6-0.5-0.5-0.9-0.80.40.60.80.8-0.80.9-0.90.30.60.4
Delta distance traveled before/after self-admin1.51.73.30.70.2-0.60.00.8-0.6-1.11.2-0.21.71.71.61.8-1.5-1.3-1.5-1.51.5-1.51.5-1.0-1.8-1.7
Delta ambulatory time before/after self-admin1.12.04.20.60.2-0.6-0.11.0-0.9-1.31.3-0.11.91.91.72.1-1.7-1.4-1.5-1.51.5-1.51.5-1.1-2.0-1.8
Parametrial fat weight0.10.31.2-0.20.7-0.30.6-0.0-1.1-0.40.5-0.0-0.2-0.20.50.20.6-0.8-0.7-0.70.7-0.60.6-1.0-0.00.0
Pavlov. Cond. lever latency0.70.92.8-1.4-1.6-1.3-1.71.4-0.5-1.00.9-1.01.01.00.70.6-1.2-0.3-0.2-0.20.2-0.30.3-0.7-0.9-0.9
Pavlov. Cond. magazine entry latency0.20.30.50.1-0.20.50.4-0.40.70.5-0.50.7-0.3-0.3-0.4-0.20.40.70.70.7-0.70.7-0.70.70.40.6
Pavlov. Cond. change in total contacts1.31.44.71.41.41.62.2-1.61.21.2-1.11.9-1.1-1.1-0.5-0.51.20.80.70.7-0.70.7-0.71.21.11.3
Pavlov. Cond. index score0.20.30.70.60.60.70.9-0.80.30.5-0.40.7-0.6-0.6-0.2-0.00.70.30.30.3-0.30.3-0.30.50.50.5
Pavlov. Cond. latency score0.40.51.61.01.21.01.2-1.10.40.7-0.70.8-0.8-0.8-0.4-0.21.00.20.20.2-0.20.3-0.30.60.70.7
Pavlov. Cond. lever contacts0.20.21.20.60.70.51.1-0.7-0.00.4-0.30.5-0.6-0.6-0.4-0.20.80.00.00.0-0.00.1-0.10.20.60.6
Pavlov. Cond. magazine entry number0.10.20.7-0.20.4-0.4-0.40.2-0.5-0.20.2-0.80.10.10.1-0.0-0.1-0.5-0.5-0.50.5-0.60.6-0.6-0.2-0.4
Pavlov. Cond. intertrial magazine entries0.10.20.80.3-0.30.30.90.1-0.0-0.00.00.9-0.1-0.1-0.3-0.50.00.30.40.4-0.40.4-0.40.20.30.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.70.70.70.70.8-0.70.30.4-0.30.7-0.3-0.30.00.20.40.10.10.1-0.10.1-0.10.50.20.2
Pavlov. Cond. response bias0.30.41.20.50.10.71.0-0.60.40.6-0.51.1-0.4-0.4-0.6-0.50.50.60.70.7-0.70.7-0.70.70.60.8
Pavlov. Cond. lever latency0.50.81.9-0.10.60.70.5-1.01.40.9-0.90.3-1.1-1.1-1.0-1.11.30.80.70.7-0.70.8-0.80.51.11.0
Pavlov. Cond. magazine entry latency0.30.51.31.10.60.90.4-0.90.20.9-0.90.7-0.6-0.6-0.3-0.20.50.50.60.6-0.60.6-0.61.10.60.5
Pavlov. Cond. change in total contacts0.20.51.60.70.1-0.3-0.00.4-1.3-0.60.6-0.00.90.91.01.1-0.8-0.8-0.7-0.70.7-0.80.8-0.3-0.8-0.8
Pavlov. Cond. index score0.10.10.80.80.20.3-0.1-0.3-0.90.4-0.40.1-0.1-0.10.00.20.1-0.00.20.2-0.20.2-0.20.50.10.0
Pavlov. Cond. latency score0.10.21.01.00.50.50.3-0.5-0.80.4-0.50.4-0.2-0.20.00.20.2-0.00.10.1-0.10.1-0.10.60.20.1
Pavlov. Cond. lever contacts0.40.52.0-0.0-0.8-0.6-0.60.9-1.4-0.70.7-0.30.90.90.80.9-1.1-0.7-0.5-0.50.5-0.50.5-0.4-0.8-0.8
Pavlov. Cond. magazine entry number0.50.61.2-0.9-0.6-0.8-0.41.10.2-1.01.0-0.61.01.00.30.2-1.0-0.5-0.8-0.80.8-0.80.8-1.1-1.0-0.9
Pavlov. Cond. intertrial magazine entries1.12.43.1-1.0-0.5-1.5-1.01.6-1.6-1.81.8-1.41.51.51.51.4-1.6-1.8-1.7-1.71.7-1.71.7-1.7-1.7-1.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.80.70.30.40.0-0.5-0.90.4-0.50.2-0.3-0.3-0.00.10.30.00.30.3-0.30.3-0.30.60.30.2
Pavlov. Cond. response bias0.10.20.90.1-0.6-0.4-0.70.5-1.0-0.30.2-0.40.40.40.40.6-0.7-0.4-0.2-0.20.2-0.20.2-0.1-0.5-0.5
Time in closed arm before self-admin0.20.41.91.01.11.01.4-0.6-0.20.4-0.31.2-0.8-0.8-0.1-0.10.30.20.10.1-0.10.2-0.20.8-0.10.3
Time in closed arm after self-admin0.70.81.70.20.6-0.30.90.7-1.0-1.01.10.70.90.91.01.0-0.9-1.0-1.0-1.01.0-0.80.8-0.3-1.3-1.1
Time in open arm before self-admin3.54.38.6-1.6-1.4-2.5-2.62.1-1.5-2.12.0-2.91.81.81.92.0-1.4-2.1-2.1-2.12.1-2.22.2-2.6-1.8-2.0
Time in open arm after self-admin0.60.61.20.1-0.70.4-0.9-0.50.70.9-1.0-0.2-0.4-0.4-0.8-0.70.31.01.11.1-1.11.0-1.00.70.90.6
Bone: periosteal estimation0.40.83.7-1.9-1.3-1.4-0.91.1-0.9-1.01.0-1.30.20.20.40.5-0.1-0.8-0.7-0.70.7-0.70.7-1.2-0.2-0.1
Bone: periosteal perimeter0.30.63.3-1.8-1.2-1.2-1.00.9-0.5-0.70.7-1.4-0.3-0.3-0.00.10.3-0.4-0.4-0.40.4-0.30.3-0.90.10.2
Bone: post-yield work0.81.46.61.92.31.82.6-1.50.51.1-1.01.7-0.6-0.6-1.2-1.30.80.30.20.2-0.20.2-0.21.10.50.5
Progressive ratio test 1 active lever presses0.40.61.1-0.8-0.5-0.9-0.70.90.4-0.90.9-0.60.90.91.00.8-1.0-0.5-0.8-0.80.8-0.90.9-1.1-0.8-0.6
Progressive ratio test 1 breakpoint0.50.81.2-0.8-0.5-0.9-0.71.00.2-1.01.0-0.71.01.01.10.9-1.1-0.6-0.9-0.90.9-1.01.0-1.1-1.0-0.7
Progressive ratio test 1 inactive lever presses0.00.11.40.2-0.00.2-0.1-0.11.20.2-0.20.30.30.3-0.1-0.2-0.30.50.30.3-0.30.3-0.30.0-0.2-0.1
Progressive ratio test 2 active lever presses0.71.02.6-1.6-1.4-1.6-1.41.3-0.6-1.21.1-1.30.60.61.10.5-0.7-0.7-0.7-0.70.7-0.80.8-1.4-0.6-0.5
Progressive ratio test 2 breakpoint1.01.32.6-1.6-1.3-1.6-1.51.4-0.7-1.31.3-1.40.70.71.30.7-0.8-0.8-0.9-0.90.9-0.90.9-1.5-0.8-0.7
Progressive ratio test 2 inactive lever presses0.10.20.9-0.5-1.0-0.6-0.60.60.6-0.20.1-0.30.50.5-0.3-0.8-0.30.40.30.3-0.30.3-0.3-0.4-0.1-0.0
Incentive Sensitization - Responses0.20.51.2-0.6-0.50.00.1-0.3-0.00.5-0.50.2-1.0-1.0-0.6-1.10.90.80.90.9-0.90.9-0.90.31.11.1
Incentive Sensitization - Breakpoint0.20.40.9-0.7-0.6-0.2-0.1-0.1-0.20.3-0.4-0.1-1.0-1.0-0.4-0.90.80.60.80.8-0.80.7-0.70.11.00.9
Sum of active levers in priming session hrs 5-60.80.72.8-0.5-0.3-0.9-0.50.7-1.2-1.01.0-0.80.70.71.00.8-0.4-1.0-0.9-0.90.9-0.90.9-1.7-0.5-0.7
Progressive ratio0.51.58.2-1.7-1.7-1.6-2.91.6-0.2-1.00.8-2.21.31.30.30.2-1.3-0.4-0.4-0.40.4-0.30.3-0.9-1.0-1.3
Food seeking constrained by brief footshock1.72.14.5-1.4-0.7-1.7-1.01.5-2.0-1.71.7-1.51.11.11.51.3-0.6-1.7-1.5-1.51.5-1.51.5-2.1-1.1-1.0
Seeking ratio, punishment vs. effort0.30.72.70.81.20.31.7-0.4-0.7-0.20.40.8-0.4-0.41.01.00.4-0.9-0.9-0.90.9-1.01.0-0.7-0.10.2
Retroperitoneal fat weight0.52.14.5-1.6-1.6-1.9-1.91.7-2.1-1.61.5-1.71.51.51.41.4-1.1-1.3-1.1-1.11.1-1.01.0-1.6-1.1-1.3
Reaction time number correct0.20.82.10.40.6-0.4-0.40.3-0.3-0.50.5-1.10.90.90.80.6-0.7-1.3-1.5-1.51.5-1.41.4-0.5-0.8-1.1
Reaction time mean minus median0.42.75.2-0.0-0.20.90.3-1.51.11.8-1.80.5-1.6-1.6-2.0-2.32.01.71.91.9-1.92.0-2.01.52.02.0
Reaction time mean minus median AUC0.31.93.80.50.21.00.6-1.50.81.6-1.70.9-1.2-1.2-1.4-1.91.51.41.61.6-1.61.7-1.71.61.61.6
Reaction time num false alarms1.22.05.11.11.11.51.1-1.42.31.6-1.60.8-1.7-1.7-1.5-1.41.61.51.21.2-1.21.2-1.21.11.51.5
Reaction time num false alarms AUC1.02.45.30.60.31.20.6-1.22.31.7-1.70.7-1.8-1.8-1.9-1.71.61.91.71.7-1.71.7-1.71.21.71.7
Reaction time trials correct on left0.20.82.10.40.6-0.4-0.40.3-0.3-0.50.5-1.10.90.90.80.6-0.7-1.3-1.5-1.51.5-1.41.4-0.5-0.8-1.1
Reaction time trials on left0.20.71.80.40.6-0.4-0.40.2-0.2-0.40.4-1.10.70.70.70.5-0.6-1.2-1.4-1.41.4-1.21.2-0.4-0.7-1.0
Reaction time mean0.71.62.7-0.3-0.70.4-0.7-0.91.21.2-1.4-0.3-1.3-1.3-1.5-1.51.41.51.51.5-1.51.6-1.60.71.51.4
Reaction time mean AUC0.71.62.7-0.5-0.90.3-0.8-0.81.31.2-1.3-0.4-1.3-1.3-1.5-1.41.41.51.61.6-1.61.6-1.60.71.61.4
Median of all reaction times0.40.71.2-0.6-1.1-0.2-1.1-0.20.90.6-0.7-0.8-0.7-0.7-0.9-0.80.71.01.01.0-1.01.0-1.00.00.90.7
Reaction time omissions2.64.28.2-0.70.20.9-0.3-1.81.52.1-2.2-0.1-2.9-2.9-2.3-1.92.82.22.32.3-2.32.4-2.41.12.72.5
Reaction time false alarm rate1.62.23.70.40.11.10.7-1.01.81.4-1.51.0-1.6-1.6-1.7-1.51.41.91.81.8-1.81.8-1.81.11.51.6
Reaction time premature initiation rate0.10.10.6-0.5-0.7-0.1-0.40.4-0.2-0.20.20.10.40.40.30.1-0.30.10.20.2-0.20.0-0.00.2-0.5-0.1
Reaction time premature initiations0.10.20.5-0.5-0.6-0.3-0.70.4-0.1-0.30.2-0.60.50.50.30.1-0.3-0.3-0.3-0.30.3-0.40.4-0.1-0.5-0.3
Std. dev. reaction times0.82.65.1-0.0-0.10.90.0-1.51.31.8-1.90.3-1.7-1.7-2.0-2.31.91.71.91.9-1.92.0-2.01.42.01.9
Reaction time trials completed0.20.71.80.40.6-0.4-0.40.2-0.2-0.40.4-1.10.70.70.70.5-0.6-1.2-1.4-1.41.4-1.21.2-0.4-0.7-1.0
Reaction time trials AUC0.20.71.70.30.3-0.5-0.40.4-0.3-0.50.6-1.00.90.90.70.5-0.7-1.1-1.3-1.31.3-1.21.2-0.4-0.7-1.0
Run reversals in cocaine runway, females0.60.71.40.71.20.10.10.00.1-0.40.4-0.20.90.90.81.2-0.7-0.8-1.1-1.11.1-1.11.1-0.5-1.0-1.1
Run reversals in cocaine runway, males0.60.73.40.40.7-0.2-0.5-0.0-0.1-0.30.3-0.40.80.81.51.8-0.9-0.8-1.0-1.01.0-1.01.0-0.3-1.0-0.7
Latency to leave start box in cocaine runway0.40.53.61.41.90.91.2-0.90.30.3-0.20.9-0.1-0.10.50.2-0.1-0.3-0.6-0.60.6-0.60.60.2-0.2-0.2
Latency to leave start box in cocaine runway, F0.50.62.40.91.61.01.5-1.10.20.6-0.51.1-0.9-0.9-0.2-0.30.70.20.10.1-0.10.1-0.10.50.60.7
Latency to leave start box in cocaine runway, M1.21.22.91.10.90.10.00.3-0.1-0.70.70.11.71.71.30.9-1.7-1.0-1.1-1.11.1-1.11.1-0.4-1.6-1.6
Std. dev. time between licks in bursts0.30.64.71.01.30.92.2-0.60.80.00.11.5-0.1-0.10.50.5-0.1-0.3-0.6-0.60.6-0.60.60.2-0.20.1
Total sessions with >9 infusions0.40.52.10.60.70.91.2-0.81.00.7-0.61.5-0.2-0.2-0.1-0.00.10.70.50.5-0.50.4-0.40.80.40.7
Short access day 1 total inactive lever presses0.20.41.40.50.40.10.40.4-0.1-0.40.40.81.21.20.50.9-1.1-0.2-0.4-0.40.4-0.30.30.2-1.0-0.8
Short access day 10 total inactive lever presses0.10.72.31.50.71.30.4-0.71.41.0-1.00.90.20.2-1.1-0.6-0.21.00.80.8-0.80.9-0.91.00.0-0.1
Short access day 1 total infusions0.81.64.30.80.71.51.7-1.40.91.4-1.32.1-1.1-1.1-0.8-0.60.91.41.31.3-1.31.2-1.21.41.21.6
Short access day 10 total infusions0.30.52.21.11.11.11.3-0.81.00.5-0.41.5-0.1-0.10.30.3-0.30.40.10.1-0.10.1-0.10.6-0.00.2
Short access total infusions0.10.21.10.40.40.50.7-0.30.80.2-0.11.00.20.20.40.4-0.50.30.10.1-0.10.0-0.00.2-0.10.1
Short access day 1 locomotion0.30.53.40.80.31.01.5-0.40.40.4-0.41.80.20.2-0.1-0.1-0.40.60.50.5-0.50.4-0.41.1-0.00.4
Short access day 10 total locomotion0.10.52.71.31.61.11.2-1.1-0.20.7-0.61.2-0.4-0.40.30.50.2-0.1-0.1-0.10.1-0.10.10.90.00.3
Short access total locomotion0.40.62.71.71.41.21.3-1.00.20.7-0.61.40.00.00.30.3-0.20.10.00.0-0.00.0-0.01.0-0.10.1
One hour access (0.3 mA shock)0.40.51.3-1.0-0.2-1.0-0.50.6-1.0-0.80.8-0.7-0.1-0.11.00.80.1-0.8-0.7-0.70.7-0.50.5-1.1-0.2-0.1
Compulsive drug intake0.10.20.9-0.5-0.0-0.3-0.20.2-0.9-0.30.3-0.5-0.6-0.60.10.80.4-0.5-0.3-0.30.3-0.20.2-0.50.10.1
One hour access (shock baseline)0.10.40.9-0.6-0.5-0.9-0.80.6-0.1-0.70.7-0.80.50.50.90.3-0.5-0.5-0.6-0.60.6-0.60.6-1.0-0.5-0.5
Social response proportion0.30.41.30.90.60.60.3-0.81.20.8-0.8-0.3-0.6-0.6-1.0-0.60.70.30.20.2-0.20.2-0.20.70.50.3
Social responses0.81.01.90.70.2-0.7-0.80.5-0.9-0.60.6-1.31.01.00.80.9-0.9-1.4-1.4-1.41.4-1.31.3-0.5-1.1-1.4
Social time0.71.12.41.50.71.10.6-1.10.21.3-1.30.8-1.0-1.0-1.5-1.20.71.11.21.2-1.21.0-1.01.30.70.7
Soleus weight0.30.84.4-2.1-1.9-1.3-1.80.9-0.6-0.40.3-1.00.20.20.2-0.0-0.00.30.60.6-0.60.5-0.5-0.50.20.3
Bone: stiffness0.30.61.1-0.6-0.2-0.7-0.20.7-1.0-0.80.8-0.70.60.60.60.5-0.6-1.0-1.0-1.01.0-1.01.0-0.8-0.7-0.6
Tibialis anterior weight2.79.339.4-6.3-5.8-5.0-5.94.0-2.2-2.92.6-5.00.80.81.41.5-0.6-1.1-0.7-0.70.7-0.70.7-3.1-0.5-0.5
Time to tail flick, vehicle, before self-admin0.91.12.31.21.21.41.2-1.11.31.1-1.11.2-0.6-0.6-1.2-1.50.71.10.90.9-0.91.0-1.00.80.80.7
Time to tail flick, vehicle, after self-admin1.73.46.7-1.0-1.90.5-0.6-0.51.11.5-1.60.2-1.6-1.6-2.6-2.41.52.32.62.6-2.62.6-2.61.22.01.9
Time to tail flick, test, before self-admin1.11.32.10.70.61.31.0-1.30.31.2-1.21.5-0.9-0.9-1.1-0.50.91.31.41.4-1.41.4-1.41.41.11.2
Time to tail flick, test, after self-admin0.50.51.3-0.6-1.2-0.10.10.30.40.2-0.20.4-0.5-0.5-0.9-1.00.30.91.01.0-1.01.1-1.10.40.60.7
Delta time to tail flick, vehicle, before/after SA1.01.05.6-1.8-2.4-0.8-1.30.70.40.0-0.2-1.0-1.0-1.0-1.0-0.60.70.91.01.0-1.00.9-0.9-0.10.80.9
Delta time to tail flick, test, before/after SA0.60.72.0-1.2-1.4-1.3-0.71.4-0.4-1.11.1-0.90.60.60.6-0.0-0.5-0.6-0.6-0.60.6-0.60.6-1.1-0.6-0.5
Tibia length0.82.29.4-1.8-2.2-2.2-3.11.7-1.6-1.21.0-2.41.71.70.60.6-1.5-0.8-0.5-0.50.5-0.50.5-0.9-0.9-1.3
Ambulatory time before self-admin1.13.47.3-0.30.21.11.2-1.61.31.6-1.61.1-2.6-2.6-1.8-2.12.71.81.91.9-1.91.9-1.90.92.62.7
Ambulatory time after self-admin0.91.43.20.90.71.21.8-1.20.91.1-1.01.7-1.3-1.3-1.0-0.91.41.21.11.1-1.11.1-1.10.71.21.5
Bone: tissue strength2.83.05.3-1.4-0.7-2.0-0.51.8-2.1-2.02.1-1.41.41.41.51.3-1.1-2.1-2.0-2.02.0-2.12.1-2.3-1.4-1.4
Total heroin consumption0.10.21.1-0.7-1.1-0.3-0.50.3-0.8-0.20.2-0.2-0.1-0.10.0-0.2-0.10.00.30.3-0.30.2-0.2-0.40.20.2
Bone: trabecular number1.12.13.11.20.41.50.8-1.50.61.6-1.71.2-1.8-1.8-1.6-1.31.31.51.61.6-1.61.7-1.71.61.51.5
Bone: trabecular spacing1.31.82.8-1.0-0.3-1.3-0.71.2-1.2-1.61.6-1.21.11.11.61.4-1.1-1.6-1.5-1.51.5-1.71.7-1.5-1.3-1.4
Bone: trabecular thickness0.30.41.1-0.1-0.10.3-0.2-0.50.90.7-0.7-0.1-1.0-1.0-0.7-0.51.00.60.50.5-0.50.6-0.60.30.90.9
Bone: trabecular tissue density0.50.82.50.50.60.80.3-1.01.61.0-1.0-0.1-1.5-1.5-0.8-0.91.30.60.40.4-0.40.4-0.40.81.01.0
Water consumed over 24 hours0.30.62.3-1.5-0.3-0.9-0.50.6-0.6-0.80.8-0.9-0.3-0.31.00.90.5-0.9-0.9-0.90.9-0.80.8-0.9-0.00.1
Number of responses in last shaping day1.72.24.80.4-0.11.10.6-1.12.21.6-1.61.2-0.9-0.9-1.6-1.91.22.01.81.8-1.81.8-1.81.41.51.7