Hub : Genes

Stpg2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Stpg2 0.13 0.05 2.4e-15 0.13 0.11 0.11 0.09 2.3e-14 8.1e-12 1.4e-12 1.5e-10
2 Brain gene expression Stpg2 0.05 0.03 1.6e-04 0.06 0.04 0.05 0.01 6.2e-06 6.3e-05 1.9e-05 5.9e-02
3 PL gene expression Stpg2 0.09 0.04 7.7e-11 0.09 0.09 0.1 0.05 3.0e-10 2.5e-10 2.9e-11 1.5e-06
4 RMTg isoform ratio XM_017591047.3 0.16 0.09 3.7e-03 0.08 0.11 0.1 0.06 3.0e-03 6.4e-04 1.4e-03 9.2e-03
5 NAcc gene expression Stpg2 0.09 0.04 1.1e-15 0.08 0.1 0.1 0.07 1.3e-12 5.7e-15 7.4e-15 3.8e-11
6 BLA gene expression Stpg2 0.08 0.05 7.0e-03 0.03 0 0 0 6.6e-03 2.1e-01 3.3e-01 2.3e-01
7 pVTA alternative TSS XM_017591047.3 0.04 0.03 1.8e-03 0.02 0.03 0.03 0.02 1.6e-02 2.0e-03 3.9e-03 5.4e-03
8 pVTA alternative TSS NM_001100993.1 0.05 0.03 1.2e-03 0.03 0.03 0.03 0.03 2.4e-03 1.9e-03 3.8e-03 2.2e-03
9 Brain alternative TSS XM_017591047.3 0.04 0.03 4.4e-03 0 0.02 0.01 0.01 1.3e-01 4.5e-03 2.1e-02 2.6e-02
10 LHb alternative TSS XM_017591047.3 0.37 0.11 8.5e-06 0.25 0.19 0.18 0.2 1.1e-06 3.2e-05 4.2e-05 2.1e-05
11 LHb alternative TSS XM_017591047.3 0.37 0.12 1.1e-05 0.21 0.19 0.18 0.19 8.4e-06 2.3e-05 3.8e-05 3.3e-05
12 Liver alternative TSS XM_017591047.3 0.04 0.02 1.1e-03 0.03 0.02 0.03 0.02 2.0e-04 3.0e-03 2.9e-04 1.6e-03
13 Liver alternative TSS XM_017591047.3 0.07 0.04 1.1e-04 0.04 0.03 0.02 0.03 5.6e-05 5.5e-04 1.8e-03 5.2e-04
14 IC gene expression Stpg2 0.1 0.06 5.3e-03 0.04 0 -0.01 0 7.1e-03 2.2e-01 8.6e-01 2.1e-01
15 PL alternative TSS XM_017591047.3 0.06 0.03 2.0e-06 0.04 0.04 0.04 0.05 1.1e-05 1.1e-05 8.7e-05 9.0e-06
16 PL alternative TSS NM_001100993.1 0.06 0.03 3.1e-06 0.05 0.04 0.04 0.04 5.9e-06 1.4e-05 8.2e-05 1.2e-05
17 PL alternative TSS NM_001100993.1 0.06 0.03 7.8e-06 0.04 0.04 0.04 0.04 9.7e-06 8.8e-05 7.1e-05 3.0e-05
18 PL alternative TSS XM_017591047.3 0.06 0.03 4.4e-06 0.05 0.04 0.04 0.04 8.3e-06 8.6e-05 5.8e-05 4.2e-05
19 pVTA alternative TSS NM_001100993.1 0.06 0.03 9.6e-04 0.04 0.04 0.03 0.03 5.6e-04 8.3e-04 1.2e-03 4.2e-03
20 pVTA alternative TSS XM_017591047.3 0.05 0.03 1.1e-03 0.04 0.03 0.03 0.03 3.5e-04 8.7e-04 1.7e-03 2.7e-03
21 pVTA gene expression Stpg2 0.15 0.07 1.3e-09 0.13 0.13 0.14 0.14 9.8e-11 8.4e-11 3.3e-11 4.6e-11
22 NAcc alternative TSS XM_017591047.3 0.07 0.03 6.3e-12 0.08 0.08 0.08 0.08 1.3e-11 4.0e-12 4.2e-12 2.1e-12
23 NAcc alternative TSS XM_017591047.3 0.07 0.03 1.5e-10 0.07 0.07 0.06 0.07 1.8e-10 1.8e-11 7.5e-10 5.4e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.10.10.80.20.20.2-0.3-0.00.9-0.00.0-0.40.80.8-0.1-0.3-0.4-0.30.10.1-0.10.0-0.00.20.30.1
Area under the delay curve0.20.21.2-1.1-0.7-0.6-0.1-0.4-0.50.4-0.40.3-0.3-0.3-0.1-0.30.40.3-0.2-0.20.2-0.20.2-0.8-0.3-0.3
BMI with tail1.03.47.32.72.02.5-2.22.42.6-2.32.2-1.9-1.2-1.2-2.0-2.20.9-1.61.41.4-1.41.2-1.21.9-1.4-1.2
BMI without tail1.13.48.12.62.12.5-2.82.12.1-2.01.8-2.2-1.8-1.8-2.0-2.31.3-1.51.21.2-1.21.1-1.11.3-1.4-1.3
Body weight1.25.312.43.23.53.3-3.23.13.1-2.62.4-2.2-2.3-2.3-2.3-2.81.8-1.51.11.1-1.10.9-0.91.7-1.6-1.4
Weight adjusted by age0.50.83.9-1.6-2.0-1.21.4-1.4-0.50.8-0.70.60.30.3-0.5-0.8-0.9-0.20.50.5-0.50.5-0.5-0.50.50.5
Bone surface0.10.10.60.30.00.1-0.1-0.30.70.1-0.1-0.40.80.80.10.1-0.8-0.10.10.1-0.1-0.10.1-0.00.50.4
Bone volume0.20.41.90.60.20.1-0.3-0.40.40.3-0.4-0.71.41.40.50.4-1.10.0-0.1-0.10.1-0.30.30.00.90.8
Breakpoint value in progressive ratio session0.20.20.50.40.60.40.10.60.7-0.60.70.3-0.5-0.5-0.6-0.20.5-0.30.20.2-0.20.3-0.30.4-0.4-0.2
Number of licking bursts1.42.34.31.00.01.30.71.51.3-1.81.9-0.6-1.1-1.1-1.2-1.30.6-1.92.12.1-2.12.1-2.12.0-1.3-1.1
Context. condit. distance diff. score0.20.21.0-0.10.3-0.10.80.40.7-0.60.61.0-0.5-0.5-0.6-0.50.6-0.20.10.1-0.10.1-0.1-0.0-0.5-0.4
Locomotion velocity, session 10.40.41.71.30.70.8-0.90.8-0.9-0.60.6-0.9-0.3-0.3-0.3-0.30.4-0.20.40.4-0.40.5-0.50.9-0.3-0.3
Locomotion distance, session 10.40.41.70.50.40.3-0.40.8-1.1-0.60.60.0-1.1-1.1-0.5-0.51.3-0.10.40.4-0.40.5-0.50.3-0.9-0.8
Locomotion velocity, session 20.10.20.8-0.2-0.8-0.20.0-0.1-0.90.00.0-0.2-0.5-0.5-0.2-0.10.2-0.20.50.5-0.50.5-0.50.4-0.3-0.4
Locomotion distance, session 20.50.77.7-0.8-0.6-1.20.5-0.6-2.80.8-0.80.9-0.2-0.20.40.50.30.9-0.5-0.50.5-0.50.5-0.80.00.2
Locomotion velocity, session 30.40.51.21.00.90.10.10.1-0.90.2-0.20.11.11.10.80.8-0.80.7-0.6-0.60.6-0.70.70.00.80.9
Locomotion distance, session 30.10.10.60.60.80.3-0.30.6-0.3-0.40.4-0.20.40.40.00.1-0.0-0.00.00.0-0.0-0.10.10.2-0.1-0.2
Stereotopy head waving bouts, day 30.20.21.01.00.90.6-0.70.7-0.7-0.30.2-0.8-0.5-0.50.50.50.30.10.00.0-0.00.1-0.10.4-0.1-0.0
Stereotopy head waving duration, day 30.70.93.01.71.71.5-1.01.50.1-1.01.0-1.1-1.0-1.00.00.10.8-0.30.40.4-0.40.5-0.51.1-0.5-0.3
Locomotion velocity, session 71.11.22.90.8-0.10.80.10.90.4-1.21.3-0.90.10.1-1.2-1.10.2-1.41.71.7-1.71.6-1.61.5-0.9-0.8
Locomotion distance, session 70.70.81.70.20.10.10.60.90.4-1.11.20.5-0.8-0.8-1.3-1.21.2-0.81.11.1-1.11.0-1.00.5-1.3-1.1
Stereotopy head waving bouts, day 71.92.14.7-0.3-0.0-0.90.0-1.0-2.21.6-1.60.41.11.12.12.1-1.31.8-1.7-1.71.7-1.81.8-1.21.61.4
Stereotopy head waving duration, day 73.03.66.1-0.6-0.5-1.40.7-1.7-2.42.1-2.10.72.12.12.52.5-2.12.0-1.9-1.91.9-2.02.0-1.62.32.2
Locomotion velocity, session 80.10.20.4-0.2-0.5-0.10.10.1-0.5-0.20.20.0-0.6-0.6-0.3-0.20.6-0.40.50.5-0.50.5-0.50.2-0.6-0.6
Locomotion distance, session 80.30.42.1-0.3-0.0-0.60.80.3-0.9-0.20.31.4-0.7-0.7-0.7-0.61.10.2-0.0-0.00.0-0.00.0-0.5-0.7-0.4
Degree of sensitization distance1.41.43.4-0.4-0.30.10.60.81.1-1.11.20.6-1.8-1.8-1.5-1.41.8-1.11.21.2-1.21.3-1.30.5-1.7-1.4
Degree of sensitization stereotypy2.73.04.8-0.8-0.2-1.30.2-1.5-2.11.9-2.00.71.61.62.12.2-1.61.9-2.0-2.02.0-2.12.1-1.81.91.7
Conditioned locomotion1.92.24.1-1.3-1.3-1.50.5-2.0-1.32.0-2.00.51.81.81.51.5-1.71.1-1.2-1.21.2-1.21.2-1.61.91.5
Cocaine response after cond. corrected0.30.41.60.1-1.0-0.20.1-1.0-0.50.7-0.7-0.31.01.00.40.5-1.30.0-0.1-0.10.10.0-0.0-0.10.90.8
Cocaine response after cond. not corrected0.30.41.8-0.6-1.3-0.5-0.1-1.1-0.80.8-0.9-0.50.60.60.40.3-0.8-0.00.10.1-0.10.2-0.2-0.30.50.2
Cocaine response before conditioning0.30.31.4-1.2-0.2-0.4-0.60.1-0.20.1-0.1-0.2-0.9-0.9-0.3-0.51.00.00.20.2-0.20.1-0.1-0.4-0.9-1.0
Saline control response1.82.45.0-1.7-0.4-2.00.9-0.9-2.21.6-1.61.70.90.91.91.8-0.02.1-1.7-1.71.7-1.71.7-2.20.70.8
Bone: connectivity density0.10.20.9-1.0-0.6-0.60.7-0.60.80.3-0.30.70.30.3-0.1-0.2-0.20.0-0.1-0.10.1-0.20.2-0.40.30.1
Bone: cortical apparent density0.40.61.20.50.80.8-0.61.10.4-0.90.9-0.5-0.8-0.8-0.7-0.61.0-0.70.70.7-0.70.7-0.70.5-0.9-0.9
Bone: cortical area1.42.26.12.51.82.2-1.81.72.1-1.61.5-2.2-0.4-0.4-1.0-1.10.6-1.51.21.2-1.21.2-1.21.6-0.6-0.6
Bone: cortical porosity0.10.10.30.10.00.0-0.6-0.1-0.40.3-0.3-0.3-0.2-0.20.30.10.10.3-0.2-0.20.2-0.30.3-0.4-0.10.0
Bone: cortical porosity0.00.00.30.3-0.00.1-0.5-0.1-0.20.2-0.2-0.2-0.1-0.10.0-0.1-0.00.2-0.1-0.10.1-0.20.2-0.4-0.00.2
Bone: cortical thickness1.52.56.62.62.12.4-2.21.92.4-1.71.6-2.3-0.4-0.4-1.1-1.10.8-1.51.11.1-1.11.1-1.11.6-0.7-0.8
Bone: cortical thickness0.60.73.70.50.60.9-1.90.61.3-0.50.3-1.7-0.1-0.1-0.7-0.70.8-1.00.70.7-0.70.6-0.60.2-0.6-0.9
Bone: cortical tissue density0.40.61.40.50.90.8-0.61.20.4-1.00.9-0.4-0.9-0.9-0.7-0.61.2-0.70.70.7-0.70.7-0.70.5-1.0-1.0
Condit. Reinf. active minus inactive responses0.91.02.30.81.31.20.01.40.1-1.31.4-0.1-1.5-1.5-1.0-1.01.0-0.70.80.8-0.80.9-0.91.3-0.8-0.6
Condit. Reinf. active-inactive response ratio2.83.05.51.92.02.2-0.52.31.3-2.32.3-1.0-1.7-1.7-1.8-1.81.1-1.61.61.6-1.61.7-1.72.4-1.3-0.8
Condit. Reinf. active responses0.20.31.6-0.90.0-0.61.0-0.3-1.30.3-0.31.0-0.3-0.30.10.10.00.5-0.3-0.30.3-0.30.3-0.40.30.4
Condit. Reinf. inactive responses3.03.76.2-2.2-1.4-2.41.1-2.3-2.22.4-2.41.61.71.71.91.8-1.42.0-1.8-1.81.8-1.91.9-2.51.71.5
Incentive salience index mean0.60.81.70.60.91.0-0.11.10.4-1.11.1-0.2-1.3-1.3-0.9-0.90.8-0.80.80.8-0.80.8-0.81.1-0.7-0.6
Condit. Reinf. lever presses0.00.00.1-0.10.0-0.00.2-0.20.40.1-0.10.10.10.10.20.1-0.3-0.1-0.0-0.00.0-0.10.10.00.30.2
Condit. Reinf. active minus inactive responses0.81.03.30.70.31.0-0.91.01.8-1.01.0-1.2-0.8-0.8-0.5-0.80.7-1.31.11.1-1.11.1-1.10.9-0.9-1.1
Condit. Reinf. active-inactive response ratio1.31.54.61.50.61.4-0.31.32.1-1.51.5-1.0-0.5-0.5-0.8-1.10.3-1.61.31.3-1.31.4-1.41.5-0.7-0.8
Condit. Reinf. active responses1.21.63.20.20.51.1-1.41.31.7-1.11.1-1.5-1.6-1.6-0.8-1.01.5-1.41.31.3-1.31.3-1.30.8-1.5-1.8
Condit. Reinf. inactive responses0.40.62.4-0.70.20.2-1.10.60.2-0.30.2-0.5-1.4-1.4-0.6-0.51.6-0.30.30.3-0.30.2-0.2-0.3-1.2-1.3
Condit. Reinf. lever presses1.01.44.1-0.60.60.6-0.91.11.5-0.90.9-0.4-2.0-2.0-1.1-1.22.0-1.00.80.8-0.80.8-0.80.3-1.7-1.8
Condit. Reinf. lever reinforcers received1.11.63.30.00.61.0-1.41.31.6-1.11.0-1.4-1.6-1.6-0.8-1.01.6-1.31.21.2-1.21.1-1.10.7-1.6-1.8
Conditioned reinforcement - actives1.83.15.7-0.7-0.5-1.51.9-1.4-1.41.7-1.72.41.41.41.72.1-1.32.0-2.1-2.12.1-2.02.0-1.81.82.1
Conditioned reinforcement - inactives0.71.02.6-0.6-0.3-0.81.0-0.8-1.60.9-0.91.20.70.71.01.2-0.71.3-1.1-1.11.1-1.11.1-0.61.01.0
Conditioned locomotion2.33.07.5-1.8-1.4-2.02.2-1.9-0.81.9-1.92.70.90.91.51.9-0.81.8-1.9-1.91.9-1.81.8-2.01.41.6
Patch foraging indifference point 0 sec0.40.73.8-1.6-1.2-1.21.7-0.6-0.40.4-0.32.0-0.2-0.2-0.30.30.60.3-0.3-0.30.3-0.30.3-1.1-0.3-0.1
Patch foraging indifference point AUC0.91.32.21.41.31.5-0.81.41.4-1.41.4-1.1-1.1-1.1-0.7-0.40.8-1.11.01.0-1.01.0-1.01.4-0.7-0.9
Delay disc. indifference point, 0s delay0.10.10.6-0.3-0.5-0.20.8-0.30.30.1-0.00.40.10.10.30.3-0.50.1-0.1-0.10.1-0.10.1-0.00.30.2
Delay disc. indifference point, 16s delay0.10.10.50.10.20.2-0.40.4-0.2-0.30.30.0-0.3-0.3-0.3-0.10.7-0.10.00.0-0.00.0-0.00.1-0.5-0.3
Delay disc. indifference point, 2s delay0.91.02.4-1.5-1.0-1.10.1-1.4-0.11.5-1.50.50.30.30.80.5-0.80.9-1.0-1.01.0-1.01.0-1.50.70.7
Delay disc. indifference point, 24s delay0.80.92.3-1.5-1.3-1.40.4-1.4-0.71.3-1.30.80.50.50.60.2-0.50.9-0.8-0.80.8-0.80.8-1.50.50.4
Delay disc. indifference point, 4s delay0.40.41.5-0.8-0.9-0.10.1-0.10.4-0.30.3-0.1-0.1-0.1-1.2-1.20.4-0.80.90.9-0.90.9-0.90.2-0.6-0.6
Delay disc. indifference point, 8s delay0.70.83.2-1.2-0.4-1.1-0.2-0.7-1.81.0-1.00.7-0.1-0.10.60.40.31.2-1.0-1.01.0-1.01.0-1.60.00.1
Indifference point function ln k0.30.52.0-1.4-1.2-1.21.1-0.8-1.10.6-0.61.20.30.3-0.1-0.30.00.3-0.1-0.10.1-0.10.1-1.0-0.10.2
Indifference point function log k0.30.52.0-1.4-1.2-1.21.1-0.8-1.10.6-0.61.20.30.3-0.1-0.30.00.3-0.1-0.10.1-0.10.1-1.0-0.10.2
Patch foraging total patch changes 0 sec0.40.74.0-1.6-1.2-1.21.7-0.6-0.30.4-0.22.0-0.3-0.3-0.40.20.70.2-0.2-0.20.2-0.20.2-1.1-0.4-0.2
Patch foraging total patch changes 12 sec0.30.41.0-0.1-0.10.20.30.50.9-0.70.70.4-1.0-1.0-0.9-0.51.0-0.60.50.5-0.50.4-0.40.3-0.8-0.8
Patch foraging total patch changes 18 sec0.30.51.3-0.1-0.6-0.01.10.30.9-0.80.91.0-0.7-0.7-1.1-0.70.6-0.80.80.8-0.80.6-0.60.2-0.7-0.5
Patch foraging total patch changes 24 sec0.10.11.0-0.4-0.5-0.31.0-0.20.2-0.00.11.0-0.1-0.1-0.40.30.1-0.10.10.1-0.10.1-0.1-0.0-0.00.2
Patch foraging total patch changes 6 sec1.21.85.20.20.00.60.51.32.3-1.61.70.7-1.8-1.8-1.9-1.21.9-1.31.11.1-1.11.1-1.10.7-1.7-1.5
Patch foraging time to switch 0 sec0.30.71.70.50.3-0.1-0.6-0.6-0.60.7-0.8-0.20.90.90.80.4-1.00.9-1.1-1.11.1-1.31.3-0.30.90.9
Patch foraging water rate 0 sec0.20.41.1-0.4-0.3-0.10.50.41.1-0.50.60.3-0.5-0.5-0.7-0.40.7-0.70.70.7-0.70.8-0.8-0.2-0.7-0.6
Patch foraging water rate 12 sec0.20.51.3-0.20.40.5-0.50.90.4-0.70.7-0.4-0.7-0.7-0.8-0.70.9-0.70.70.7-0.70.7-0.70.2-1.1-0.8
Patch foraging water rate 18 sec1.82.75.80.2-0.21.3-0.21.12.4-1.51.6-1.2-1.2-1.2-1.8-1.41.1-2.32.22.2-2.22.4-2.41.7-1.4-1.3
Patch foraging water rate 24 sec1.42.04.10.1-0.40.80.21.01.3-1.41.5-0.7-1.2-1.2-1.6-1.81.0-1.82.02.0-2.01.9-1.91.1-1.6-1.3
Patch foraging water rate 6 sec2.33.45.81.30.61.5-0.72.00.9-2.22.3-1.1-1.5-1.5-2.2-1.81.8-2.12.42.4-2.42.3-2.31.7-2.1-1.8
Seeking ratio, delayed vs. immediate footshock0.70.92.2-1.5-0.8-1.40.0-1.3-0.61.3-1.30.9-0.0-0.00.3-0.0-0.01.1-1.1-1.11.1-1.11.1-1.40.40.3
Distance traveled before self-admin2.12.77.00.80.0-0.71.1-1.3-0.81.3-1.20.82.52.51.61.8-2.61.5-1.7-1.71.7-1.61.6-0.52.42.6
Distance traveled after self-admin0.10.10.50.10.20.00.7-0.1-0.2-0.10.10.30.50.5-0.0-0.1-0.70.2-0.1-0.10.1-0.10.10.50.30.6
Extensor digitorum longus weight2.28.746.16.86.24.8-5.33.92.1-2.72.4-4.2-0.6-0.6-0.9-1.10.2-0.5-0.0-0.00.00.0-0.03.10.10.2
Bone: elastic displacement0.50.62.31.50.81.2-0.70.81.0-0.80.8-1.10.20.2-0.5-0.7-0.3-0.80.60.6-0.60.6-0.60.90.10.1
Bone: elastic work2.63.36.02.31.62.4-2.02.12.3-2.12.0-2.5-0.8-0.8-1.5-1.71.0-2.21.81.8-1.81.8-1.81.9-1.2-1.3
Bone: endosteal estimation0.00.10.30.5-0.00.10.6-0.0-0.3-0.10.20.1-0.0-0.00.20.1-0.4-0.00.10.1-0.10.2-0.20.50.30.3
Bone: endosteal perimeter0.10.21.01.00.90.6-0.30.6-0.2-0.40.4-0.6-0.1-0.10.40.3-0.2-0.00.10.1-0.10.0-0.00.60.10.1
Epididymis fat weight0.51.73.31.61.61.6-1.51.81.7-1.61.6-1.4-0.8-0.8-1.1-1.41.1-1.11.01.0-1.01.0-1.01.4-1.1-1.2
Delta time in closed arm before/after self-admin0.10.10.40.40.40.30.30.4-0.6-0.30.30.1-0.3-0.30.20.20.10.10.10.1-0.1-0.10.10.2-0.2-0.0
Delta time in open arm before/after self-admin2.72.74.3-0.8-0.2-1.60.7-1.5-1.51.8-1.91.41.31.31.81.8-1.12.0-2.1-2.12.1-2.02.0-1.81.81.7
Diff in mean of infusions in LGA sessions1.31.63.2-0.3-0.90.50.40.50.9-1.21.3-0.4-1.0-1.0-1.6-1.11.0-1.71.81.8-1.81.7-1.71.4-1.4-1.5
Delay discount exponential model param0.20.21.61.30.80.70.10.50.5-0.50.5-0.40.20.20.20.4-0.4-0.30.20.2-0.20.2-0.20.90.30.3
Extinction: sum of active levers before priming1.81.93.31.81.51.8-1.61.41.4-1.61.6-1.4-1.3-1.3-1.8-1.31.0-1.31.21.2-1.21.3-1.31.7-0.9-0.9
Active lever presses in extinction session 60.60.63.6-1.9-1.3-1.01.3-0.80.00.5-0.41.5-0.6-0.6-0.30.00.80.00.00.0-0.00.1-0.1-0.5-0.3-0.3
Bone: final force0.71.11.70.80.71.1-0.31.21.2-1.31.3-0.7-0.9-0.9-1.0-1.01.1-1.31.21.2-1.21.2-1.21.1-1.1-1.0
Bone: final moment0.91.52.20.70.61.2-0.41.21.3-1.41.4-0.9-1.0-1.0-1.1-1.11.2-1.51.41.4-1.41.5-1.51.2-1.2-1.1
Food consumed during 24 hour testing period0.70.92.70.90.00.7-0.40.70.6-1.01.0-0.7-0.4-0.4-1.6-1.60.2-1.11.31.3-1.31.2-1.20.9-0.7-0.5
Glucose1.11.73.91.30.41.4-1.11.11.0-1.41.4-1.3-0.7-0.7-1.8-2.00.7-1.51.51.5-1.51.5-1.51.5-0.9-0.9
Heart weight0.50.73.10.61.81.2-1.51.41.1-0.80.7-1.2-0.9-0.90.1-0.10.8-0.40.20.2-0.20.2-0.20.5-0.8-0.8
Delay discount hyperbolic model param0.30.32.11.51.00.9-0.10.80.5-0.70.7-0.50.00.00.10.3-0.2-0.30.30.3-0.30.3-0.31.00.20.2
Intermittent access intake day 1-15 change0.71.45.1-0.0-1.2-0.70.8-1.6-0.61.2-1.10.41.91.90.51.0-2.20.8-0.8-0.80.8-0.80.8-0.31.81.7
Intermittent access intake escalation0.61.34.80.0-1.3-0.71.0-1.5-0.31.1-1.00.51.91.90.40.8-2.20.7-0.8-0.80.8-0.80.8-0.11.81.7
Intermittent access intake escalation 20.40.42.40.8-0.60.10.2-0.60.60.2-0.1-0.31.21.2-0.30.1-1.6-0.1-0.1-0.10.1-0.10.10.61.11.0
Intermitt. access day 1 inactive lever presses0.10.41.5-0.30.4-0.0-0.60.5-0.6-0.30.30.1-1.2-1.2-0.2-0.41.2-0.00.20.2-0.20.2-0.2-0.1-1.0-1.0
Intermitt. access day 15 inactive lever presses0.10.20.70.40.80.5-0.80.8-0.4-0.40.4-0.6-0.3-0.30.20.30.50.10.00.0-0.00.1-0.10.5-0.4-0.4
Intermitt. access escalation Index0.30.51.0-0.6-0.0-0.4-0.2-0.6-0.60.9-1.00.2-0.1-0.10.90.7-0.30.9-1.0-1.01.0-1.01.0-0.50.70.5
Intermittent access day 1 total infusions0.91.42.10.80.71.2-0.51.20.9-1.31.4-0.8-1.1-1.1-1.4-1.41.3-1.21.31.3-1.31.4-1.41.4-1.2-1.0
Intermittent access day 15 total infusions0.50.72.21.00.11.1-0.20.61.0-0.91.0-0.7-0.0-0.0-1.3-1.0-0.0-1.00.90.9-0.91.0-1.01.5-0.2-0.2
Intermittent access terminal intake (last 3 days)0.60.92.20.90.21.0-0.20.71.0-1.11.1-0.6-0.4-0.4-1.5-1.00.4-1.11.11.1-1.11.1-1.11.4-0.5-0.4
Intermittent access total infusions1.61.83.21.10.81.6-0.61.41.2-1.61.7-0.9-1.1-1.1-1.8-1.61.2-1.41.41.4-1.41.5-1.51.8-1.2-1.0
Intermittent access day 1 locomotion0.20.30.6-0.30.30.30.20.40.7-0.40.50.0-0.5-0.5-0.7-0.60.8-0.60.60.6-0.60.7-0.70.3-0.6-0.4
Intermittent access day 15 total locomotion0.40.62.50.0-1.1-0.21.2-1.00.60.4-0.30.31.61.6-0.20.3-1.6-0.1-0.0-0.00.00.1-0.10.21.21.2
Intermittent access total locomotion0.20.20.90.3-0.10.40.40.01.0-0.40.4-0.10.40.4-0.7-0.4-0.3-0.60.50.5-0.50.6-0.60.80.10.3
Intermittent access standard deviation0.20.41.61.30.71.2-1.10.51.1-0.50.4-1.00.20.2-0.4-0.3-0.2-0.50.20.2-0.20.3-0.30.90.10.3
Left kidney weight0.42.08.12.32.82.1-2.31.81.7-1.41.2-1.3-1.5-1.5-1.4-1.41.0-0.60.30.3-0.30.2-0.20.8-0.7-0.4
Right kidney weight0.52.29.42.13.12.1-2.42.02.0-1.41.3-1.6-1.5-1.5-1.3-1.61.3-0.70.40.4-0.40.4-0.40.8-0.9-0.7
Cocaine induced anxiety0.10.20.3-0.3-0.20.10.50.40.1-0.50.5-0.1-0.2-0.20.00.10.1-0.50.60.6-0.60.6-0.60.3-0.4-0.5
Post-drug Anxiety0.10.10.4-0.4-0.40.00.70.0-0.2-0.10.2-0.10.20.20.30.6-0.5-0.30.40.4-0.40.4-0.40.50.1-0.1
Baseline Anxiety0.10.10.50.70.40.4-0.50.10.2-0.20.1-0.40.60.6-0.3-0.0-0.5-0.1-0.0-0.00.0-0.00.00.50.30.3
Tail length0.20.73.41.11.91.0-1.60.90.6-0.40.2-0.7-1.2-1.2-0.1-0.70.90.1-0.5-0.50.5-0.40.4-0.0-0.1-0.2
Length with tail0.41.96.41.62.51.9-2.21.71.7-1.21.0-1.1-2.0-2.0-1.1-1.61.7-0.60.10.1-0.10.1-0.10.5-0.9-0.8
Length without tail0.20.51.80.11.30.8-0.61.01.2-0.60.5-0.1-1.3-1.3-0.2-0.31.3-0.20.10.1-0.10.0-0.00.3-0.6-0.7
Times rat made contact with spout1.51.83.50.6-0.91.0-0.60.51.2-1.21.2-1.3-0.7-0.7-1.8-1.70.4-1.91.91.9-1.91.8-1.81.3-1.0-1.1
Lifetime Intake0.70.81.61.00.71.1-0.31.00.7-1.11.2-0.3-0.8-0.8-1.3-1.20.9-0.80.90.9-0.90.9-0.91.3-0.8-0.6
Liver weight, left0.10.10.50.30.30.2-0.30.10.20.1-0.2-0.30.20.20.40.7-0.40.2-0.2-0.20.2-0.30.3-0.20.40.3
Liver weight, right0.40.82.7-0.1-0.40.80.40.31.6-0.60.6-0.6-0.4-0.4-0.7-0.5-0.1-1.31.31.3-1.31.3-1.30.8-0.2-0.2
Locomotor activity0.30.41.4-0.1-0.10.3-0.60.6-0.4-0.50.5-0.7-0.7-0.7-0.5-0.80.9-0.60.70.7-0.70.9-0.90.2-0.9-1.2
Locomotor testing distance0.50.93.0-0.6-0.00.3-0.90.8-0.3-0.60.6-0.6-1.3-1.3-0.9-1.21.6-0.80.90.9-0.90.8-0.80.1-1.4-1.7
Locomotor testing rearing3.77.415.2-0.9-1.01.3-0.81.81.6-2.42.5-1.1-3.4-3.4-3.3-3.33.3-3.13.23.2-3.22.9-2.91.7-3.8-3.9
Locomotion in novel chamber0.20.31.2-0.9-1.1-0.8-0.1-0.70.10.6-0.60.3-0.3-0.30.20.40.40.2-0.3-0.30.3-0.30.3-0.8-0.2-0.6
Locomotion in novel chamber post-restriction0.20.31.40.00.70.0-1.10.4-1.20.1-0.2-0.7-0.1-0.10.60.70.80.5-0.3-0.30.3-0.50.5-0.2-0.4-0.6
Fecal boli incidents, locomotor time 10.30.41.5-0.5-0.9-0.60.2-0.7-1.20.8-0.7-0.20.80.81.00.7-0.80.4-0.1-0.10.1-0.10.1-0.10.50.4
Change in fecal boli incidents, locomotor task1.41.43.30.00.30.7-0.70.90.5-1.11.1-0.4-1.8-1.8-1.6-1.51.6-1.21.21.2-1.21.1-1.10.6-1.5-1.6
Time >=10cm from walls, locomotor time 12.02.14.31.01.41.3-0.91.91.4-1.81.8-0.7-2.1-2.1-1.1-1.12.0-1.21.01.0-1.01.0-1.01.2-2.0-1.9
Bouts of movement, locomotor time 10.20.21.1-0.2-0.5-0.00.1-0.31.1-0.10.1-0.30.30.3-0.4-0.8-0.6-0.70.50.5-0.50.5-0.50.20.0-0.0
Total resting periods, locomotor time 10.30.30.9-0.3-0.7-0.00.2-0.30.9-0.10.2-0.30.20.2-0.5-0.9-0.6-0.80.70.7-0.70.7-0.70.4-0.1-0.1
Rest time, locomotor task time 10.50.71.5-1.2-1.1-1.10.6-1.2-0.21.1-1.10.50.70.70.90.5-1.00.5-0.6-0.60.6-0.60.6-0.90.80.5
Distance moved, locomotor task time 10.91.43.61.21.21.4-1.11.70.0-1.41.4-0.8-1.9-1.9-0.8-0.61.8-0.50.60.6-0.60.7-0.70.9-1.5-1.3
Vertical activity count, locomotor time 10.20.61.50.81.00.8-0.91.10.1-0.90.8-0.5-1.2-1.2-0.5-0.01.2-0.30.30.3-0.30.2-0.20.6-0.9-0.9
Time >=10cm from walls, locomotor time 20.20.21.61.11.30.7-0.80.8-0.2-0.40.4-0.4-0.4-0.40.1-0.10.10.2-0.1-0.10.1-0.30.3-0.1-0.10.0
Bouts of movement, locomotor time 20.61.02.0-1.2-1.1-1.40.9-1.2-0.61.1-1.11.11.11.10.80.7-0.60.7-0.8-0.80.8-1.01.0-1.40.70.7
Total resting periods, locomotor time 20.61.02.4-1.4-1.4-1.61.0-1.3-0.51.1-1.11.21.11.10.60.6-0.50.7-0.7-0.70.7-0.90.9-1.40.50.5
Rest time, locomotor task time 20.30.32.1-1.5-0.6-0.8-0.3-0.70.20.7-0.80.3-0.2-0.20.1-0.00.40.5-0.7-0.70.7-0.50.5-0.5-0.1-0.4
Distance moved, locomotor task time 20.10.11.01.00.60.50.20.6-0.4-0.50.50.1-0.5-0.50.20.40.20.0-0.0-0.00.00.0-0.00.1-0.00.1
Vertical activity count, locomotor time 20.20.31.30.91.20.3-0.40.3-0.20.0-0.10.0-0.1-0.10.50.7-0.20.5-0.6-0.60.6-0.70.7-0.60.40.4
Light reinforcement 10.51.33.50.41.11.1-0.81.50.4-1.31.3-0.4-1.6-1.6-1.3-1.11.9-0.90.90.9-0.90.8-0.80.7-1.4-1.3
Light reinforcement 20.00.10.4-0.6-0.6-0.30.0-0.40.00.2-0.2-0.10.20.2-0.3-0.1-0.0-0.30.20.2-0.20.2-0.20.1-0.0-0.1
Bone: marrow area0.00.10.40.3-0.20.00.7-0.1-0.3-0.10.20.2-0.0-0.00.20.1-0.4-0.00.10.1-0.10.2-0.20.40.30.4
Bone: maximum diameter0.20.31.00.90.50.9-0.60.60.8-0.60.6-1.0-0.3-0.3-0.2-0.30.1-0.70.60.6-0.60.5-0.50.7-0.2-0.2
Bone: maximum force0.50.92.10.90.61.0-0.11.01.5-1.11.1-0.7-0.7-0.7-0.5-0.50.8-1.21.11.1-1.11.1-1.11.0-0.8-0.7
Bone: maximum moment0.71.22.30.80.41.0-0.21.01.5-1.11.2-0.9-0.9-0.9-0.7-0.70.9-1.41.41.4-1.41.4-1.41.1-0.9-0.9
Mean time between licks in bursts0.10.20.70.50.30.50.70.2-0.2-0.40.40.10.20.2-0.0-0.2-0.7-0.10.20.2-0.20.2-0.20.80.40.6
Mean num. licks in bursts0.30.41.4-0.3-0.3-0.3-1.2-0.8-0.40.8-0.9-0.40.30.30.10.2-0.30.6-0.8-0.80.8-0.80.8-0.80.50.2
Cd content in liver2.52.85.21.61.31.9-0.72.31.8-2.22.2-0.6-2.0-2.0-1.6-1.51.9-1.51.31.3-1.31.3-1.31.9-1.8-1.7
Co content in liver0.40.53.41.81.20.9-0.50.90.3-0.80.8-0.50.40.4-0.8-1.1-0.2-0.30.30.3-0.30.3-0.30.4-0.00.4
Cu content in liver0.70.93.5-1.8-1.9-0.91.4-0.70.70.10.11.2-0.9-0.9-0.9-0.90.8-0.80.70.7-0.70.7-0.7-0.2-0.8-0.7
Fe content in liver2.43.04.7-1.6-0.1-1.60.4-1.6-1.12.0-2.11.21.31.32.12.1-1.21.9-2.1-2.12.1-2.22.2-2.21.61.5
K content in liver0.30.21.4-1.0-1.2-0.50.5-0.50.00.2-0.1-0.00.20.2-0.2-0.3-0.0-0.50.60.6-0.60.6-0.60.2-0.2-0.3
Mg content in liver0.30.40.8-0.5-0.8-0.20.60.10.1-0.40.50.1-0.4-0.4-0.5-0.60.5-0.70.80.8-0.80.9-0.90.5-0.7-0.7
Mn content in liver0.40.51.11.00.90.9-0.90.90.5-0.80.8-1.0-0.3-0.3-0.4-0.80.2-0.50.50.5-0.50.6-0.60.9-0.5-0.5
Na content in liver0.20.21.4-1.2-1.1-0.50.3-0.50.00.3-0.3-0.10.10.10.20.10.2-0.50.50.5-0.50.4-0.40.0-0.3-0.5
Rb content in liver1.11.33.9-1.7-2.0-1.61.8-1.7-0.41.4-1.31.50.90.90.70.7-0.90.6-0.6-0.60.6-0.60.6-1.31.01.0
Se content in liver0.81.02.00.10.5-0.7-0.1-0.7-0.40.9-1.00.51.41.40.80.6-1.21.1-1.2-1.21.2-1.21.2-0.91.21.2
Sr content in liver0.50.42.80.61.20.5-1.70.6-0.1-0.30.2-1.0-0.8-0.8-0.4-0.60.9-0.00.10.1-0.10.1-0.10.1-0.6-0.8
Zn content in liver4.65.117.3-3.7-4.2-1.63.0-0.81.9-0.60.91.9-1.8-1.8-2.0-2.02.2-2.32.42.4-2.42.4-2.40.2-2.4-2.6
Bone: minimum diameter0.91.77.12.72.22.2-1.51.80.9-1.51.5-1.5-0.9-0.9-0.8-0.80.7-0.70.70.7-0.70.6-0.61.7-0.6-0.4
Time in familiar zone, hab. session 10.20.20.60.0-0.1-0.40.4-0.3-0.10.4-0.40.40.30.30.70.8-0.30.5-0.5-0.50.5-0.60.6-0.70.30.4
Time in novel zone, hab. session 10.20.20.6-0.2-0.10.2-0.60.10.1-0.20.2-0.80.00.0-0.3-0.30.2-0.50.50.5-0.50.6-0.60.5-0.3-0.5
Total zone transitions, hab. session 10.91.23.10.60.3-0.70.5-0.5-1.80.9-0.81.20.70.70.80.8-0.81.7-1.5-1.51.5-1.51.5-0.71.21.4
Total locomotion distance, hab. session 10.10.20.7-0.3-0.6-0.50.6-0.2-0.80.4-0.30.9-0.5-0.50.30.50.20.5-0.3-0.30.3-0.30.3-0.20.10.1
Locomotion velocity, hab. session 10.10.10.7-0.0-0.3-0.30.5-0.0-0.50.1-0.10.8-0.8-0.8-0.00.10.50.3-0.2-0.20.2-0.10.1-0.0-0.1-0.1
Time in familiar zone, hab. session 20.60.62.50.80.61.0-1.60.81.0-0.70.6-1.5-0.4-0.4-0.4-0.50.5-0.80.60.6-0.60.6-0.60.5-0.7-0.8
Time in novel zone, hab. session 20.50.52.6-1.3-0.5-1.01.4-0.6-0.80.5-0.41.6-0.0-0.00.20.20.10.7-0.4-0.40.4-0.50.5-0.60.20.3
Total zone transitions, hab. session 20.30.41.30.81.00.0-0.30.4-1.20.1-0.10.7-0.5-0.50.20.10.41.0-0.9-0.90.9-0.90.9-0.40.20.4
Total locomotion distance, hab. session 20.60.83.10.40.80.7-0.81.0-0.1-0.70.7-0.1-1.8-1.8-0.7-0.71.7-0.30.30.3-0.30.4-0.40.4-1.1-1.1
Locomotion velocity, hab. session 20.40.52.60.30.50.4-0.50.7-0.3-0.50.50.1-1.6-1.6-0.5-0.51.6-0.20.20.2-0.20.2-0.20.2-0.9-1.0
Novel to familiar place preference ratio0.50.61.40.40.40.6-0.20.70.3-0.90.90.0-1.1-1.1-1.2-1.10.9-0.60.70.7-0.70.6-0.60.7-0.9-0.8
Novelty place preference0.80.92.20.30.30.7-0.40.80.4-1.01.0-0.1-1.4-1.4-1.5-1.41.1-0.80.90.9-0.90.8-0.80.8-1.1-1.0
Time in novel zone, NPP test0.91.02.40.40.40.8-0.50.90.5-1.11.1-0.2-1.5-1.5-1.6-1.51.2-0.80.90.9-0.90.9-0.90.9-1.2-1.1
Total zone transitions, NPP test0.20.31.51.21.20.5-0.80.8-0.8-0.40.30.0-0.6-0.6-0.2-0.20.60.4-0.4-0.40.4-0.40.40.1-0.2-0.0
Total locomotion distance, NPP test0.70.92.90.60.80.9-0.61.20.4-1.01.0-0.1-1.7-1.7-0.9-0.81.6-0.70.50.5-0.50.6-0.60.7-1.1-1.1
Locomotion velocity, NPP test1.01.43.50.90.91.2-0.91.50.5-1.31.3-0.5-1.9-1.9-1.1-1.11.8-1.00.80.8-0.80.9-0.91.0-1.4-1.4
Intraocular pressure0.30.41.20.50.70.1-1.1-0.0-0.30.5-0.6-0.60.50.50.90.8-0.40.6-0.8-0.80.8-0.90.9-0.30.60.4
Delta distance traveled before/after self-admin1.61.73.3-0.7-0.20.60.00.80.6-1.11.2-0.2-1.7-1.7-1.6-1.81.5-1.31.51.5-1.51.5-1.51.0-1.8-1.7
Delta ambulatory time before/after self-admin1.62.04.2-0.6-0.20.6-0.11.00.9-1.31.3-0.1-1.9-1.9-1.7-2.11.7-1.41.51.5-1.51.5-1.51.1-2.0-1.8
Parametrial fat weight0.10.31.20.2-0.70.30.6-0.01.1-0.40.5-0.00.20.2-0.5-0.2-0.6-0.80.70.7-0.70.6-0.61.0-0.00.0
Pavlov. Cond. lever latency0.70.92.81.41.61.3-1.71.40.5-1.00.9-1.0-1.0-1.0-0.7-0.61.2-0.30.20.2-0.20.3-0.30.7-0.9-0.9
Pavlov. Cond. magazine entry latency0.20.30.5-0.10.2-0.50.4-0.4-0.70.5-0.50.70.30.30.40.2-0.40.7-0.7-0.70.7-0.70.7-0.70.40.6
Pavlov. Cond. change in total contacts1.31.44.7-1.4-1.4-1.62.2-1.6-1.21.2-1.11.91.11.10.50.5-1.20.8-0.7-0.70.7-0.70.7-1.21.11.3
Pavlov. Cond. index score0.20.30.7-0.6-0.6-0.70.9-0.8-0.30.5-0.40.70.60.60.20.0-0.70.3-0.3-0.30.3-0.30.3-0.50.50.5
Pavlov. Cond. latency score0.40.51.6-1.0-1.2-1.01.2-1.1-0.40.7-0.70.80.80.80.40.2-1.00.2-0.2-0.20.2-0.30.3-0.60.70.7
Pavlov. Cond. lever contacts0.20.21.2-0.6-0.7-0.51.1-0.70.00.4-0.30.50.60.60.40.2-0.80.0-0.0-0.00.0-0.10.1-0.20.60.6
Pavlov. Cond. magazine entry number0.10.20.70.2-0.40.4-0.40.20.5-0.20.2-0.8-0.1-0.1-0.10.00.1-0.50.50.5-0.50.6-0.60.6-0.2-0.4
Pavlov. Cond. intertrial magazine entries0.10.20.8-0.30.3-0.30.90.10.0-0.00.00.90.10.10.30.5-0.00.3-0.4-0.40.4-0.40.4-0.20.30.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.7-0.7-0.7-0.70.8-0.7-0.30.4-0.30.70.30.3-0.0-0.2-0.40.1-0.1-0.10.1-0.10.1-0.50.20.2
Pavlov. Cond. response bias0.30.41.2-0.5-0.1-0.71.0-0.6-0.40.6-0.51.10.40.40.60.5-0.50.6-0.7-0.70.7-0.70.7-0.70.60.8
Pavlov. Cond. lever latency0.60.81.90.1-0.6-0.70.5-1.0-1.40.9-0.90.31.11.11.01.1-1.30.8-0.7-0.70.7-0.80.8-0.51.11.0
Pavlov. Cond. magazine entry latency0.40.51.3-1.1-0.6-0.90.4-0.9-0.20.9-0.90.70.60.60.30.2-0.50.5-0.6-0.60.6-0.60.6-1.10.60.5
Pavlov. Cond. change in total contacts0.30.51.6-0.7-0.10.3-0.00.41.3-0.60.6-0.0-0.9-0.9-1.0-1.10.8-0.80.70.7-0.70.8-0.80.3-0.8-0.8
Pavlov. Cond. index score0.10.10.8-0.8-0.2-0.3-0.1-0.30.90.4-0.40.10.10.1-0.0-0.2-0.1-0.0-0.2-0.20.2-0.20.2-0.50.10.0
Pavlov. Cond. latency score0.10.21.0-1.0-0.5-0.50.3-0.50.80.4-0.50.40.20.2-0.0-0.2-0.2-0.0-0.1-0.10.1-0.10.1-0.60.20.1
Pavlov. Cond. lever contacts0.40.52.00.00.80.6-0.60.91.4-0.70.7-0.3-0.9-0.9-0.8-0.91.1-0.70.50.5-0.50.5-0.50.4-0.8-0.8
Pavlov. Cond. magazine entry number0.50.61.20.90.60.8-0.41.1-0.2-1.01.0-0.6-1.0-1.0-0.3-0.21.0-0.50.80.8-0.80.8-0.81.1-0.9-0.9
Pavlov. Cond. intertrial magazine entries1.62.43.11.00.51.5-1.01.61.6-1.81.8-1.4-1.5-1.5-1.5-1.41.6-1.81.71.7-1.71.7-1.71.7-1.7-1.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.8-0.7-0.3-0.40.0-0.50.90.4-0.50.20.30.30.0-0.1-0.30.0-0.3-0.30.3-0.30.3-0.60.30.2
Pavlov. Cond. response bias0.10.20.9-0.10.60.4-0.70.51.0-0.30.2-0.4-0.4-0.4-0.4-0.60.7-0.40.20.2-0.20.2-0.20.1-0.5-0.5
Time in closed arm before self-admin0.30.41.9-1.0-1.1-1.01.4-0.60.20.4-0.31.20.80.80.10.1-0.30.2-0.1-0.10.1-0.20.2-0.8-0.10.3
Time in closed arm after self-admin0.70.81.7-0.2-0.60.30.90.71.0-1.01.10.7-0.9-0.9-1.0-1.00.9-1.01.01.0-1.00.8-0.80.3-1.3-1.1
Time in open arm before self-admin3.94.38.61.61.42.5-2.62.11.5-2.12.0-2.9-1.8-1.8-1.9-2.01.4-2.12.12.1-2.12.2-2.22.6-1.8-2.0
Time in open arm after self-admin0.60.61.2-0.10.7-0.4-0.9-0.5-0.70.9-1.0-0.20.40.40.80.7-0.31.0-1.1-1.11.1-1.01.0-0.70.90.6
Bone: periosteal estimation0.40.83.71.91.31.4-0.91.10.9-1.01.0-1.3-0.2-0.2-0.4-0.50.1-0.80.70.7-0.70.7-0.71.2-0.2-0.1
Bone: periosteal perimeter0.30.63.31.81.21.2-1.00.90.5-0.70.7-1.40.30.30.0-0.1-0.3-0.40.40.4-0.40.3-0.30.90.10.2
Bone: post-yield work1.01.46.6-1.9-2.3-1.82.6-1.5-0.51.1-1.01.70.60.61.21.3-0.80.3-0.2-0.20.2-0.20.2-1.10.50.5
Progressive ratio test 1 active lever presses0.50.61.10.80.50.9-0.70.9-0.4-0.90.9-0.6-0.9-0.9-1.0-0.81.0-0.50.80.8-0.80.9-0.91.1-0.8-0.6
Progressive ratio test 1 breakpoint0.60.81.20.80.50.9-0.71.0-0.2-1.01.0-0.7-1.0-1.0-1.1-0.91.1-0.60.90.9-0.91.0-1.01.1-1.0-0.7
Progressive ratio test 1 inactive lever presses0.10.11.4-0.20.0-0.2-0.1-0.1-1.20.2-0.20.3-0.3-0.30.10.20.30.5-0.3-0.30.3-0.30.3-0.0-0.2-0.1
Progressive ratio test 2 active lever presses0.91.02.61.61.41.6-1.41.30.6-1.21.1-1.3-0.6-0.6-1.1-0.50.7-0.70.70.7-0.70.8-0.81.4-0.6-0.5
Progressive ratio test 2 breakpoint1.11.32.61.61.31.6-1.51.40.7-1.31.3-1.4-0.7-0.7-1.3-0.70.8-0.80.90.9-0.90.9-0.91.5-0.8-0.7
Progressive ratio test 2 inactive lever presses0.10.20.90.51.00.6-0.60.6-0.6-0.20.1-0.3-0.5-0.50.30.80.30.4-0.3-0.30.3-0.30.30.4-0.1-0.0
Incentive Sensitization - Responses0.40.51.20.60.5-0.00.1-0.30.00.5-0.50.21.01.00.61.1-0.90.7-0.9-0.90.9-0.90.9-0.31.11.1
Incentive Sensitization - Breakpoint0.30.40.90.70.60.2-0.1-0.10.20.3-0.4-0.11.01.00.40.9-0.80.6-0.8-0.80.8-0.70.7-0.11.00.9
Sum of active levers in priming session hrs 5-60.80.72.80.50.30.9-0.50.71.2-1.01.0-0.8-0.7-0.7-1.0-0.80.4-1.00.90.9-0.90.9-0.91.7-0.5-0.7
Progressive ratio1.01.58.21.71.71.6-2.91.60.2-1.00.8-2.2-1.3-1.3-0.3-0.21.3-0.40.40.4-0.40.3-0.30.9-1.0-1.3
Food seeking constrained by brief footshock1.72.14.51.40.71.7-1.01.52.0-1.71.7-1.5-1.1-1.1-1.5-1.30.6-1.71.51.5-1.51.5-1.52.1-1.1-1.0
Seeking ratio, punishment vs. effort0.50.72.7-0.8-1.2-0.31.7-0.40.7-0.20.40.80.40.4-1.0-1.0-0.4-0.90.90.9-0.91.0-1.00.7-0.10.2
Retroperitoneal fat weight0.52.14.51.61.61.9-1.91.72.1-1.61.5-1.7-1.5-1.5-1.4-1.41.1-1.31.11.1-1.11.0-1.01.6-1.1-1.3
Reaction time number correct0.40.82.1-0.4-0.60.4-0.40.30.3-0.50.5-1.1-0.9-0.9-0.8-0.60.7-1.31.51.5-1.51.4-1.40.5-0.8-1.1
Reaction time mean minus median1.12.75.20.00.2-0.90.3-1.5-1.11.8-1.80.51.61.62.02.3-2.01.7-1.9-1.91.9-2.02.0-1.52.02.0
Reaction time mean minus median AUC0.81.93.8-0.5-0.2-1.00.6-1.5-0.81.6-1.70.91.21.21.41.9-1.51.4-1.6-1.61.6-1.71.7-1.61.61.6
Reaction time num false alarms1.42.05.1-1.1-1.1-1.51.1-1.4-2.31.6-1.60.81.71.71.51.4-1.61.5-1.2-1.21.2-1.21.2-1.11.51.5
Reaction time num false alarms AUC1.52.45.3-0.6-0.3-1.20.6-1.2-2.31.7-1.70.71.81.81.91.7-1.61.9-1.7-1.71.7-1.71.7-1.21.71.7
Reaction time trials correct on left0.40.82.1-0.4-0.60.4-0.40.30.3-0.50.5-1.1-0.9-0.9-0.8-0.60.7-1.31.51.5-1.51.4-1.40.5-0.8-1.1
Reaction time trials on left0.40.71.8-0.4-0.60.4-0.40.20.2-0.40.4-1.1-0.7-0.7-0.7-0.50.6-1.21.41.4-1.41.2-1.20.4-0.7-1.0
Reaction time mean1.01.62.70.30.7-0.4-0.7-0.9-1.21.2-1.4-0.31.31.31.51.5-1.41.5-1.5-1.51.5-1.61.6-0.71.51.4
Reaction time mean AUC1.01.62.70.50.9-0.3-0.8-0.8-1.31.2-1.3-0.41.31.31.51.4-1.41.5-1.6-1.61.6-1.61.6-0.71.61.4
Median of all reaction times0.50.71.20.61.10.2-1.1-0.2-0.90.6-0.7-0.80.70.70.90.8-0.71.0-1.0-1.01.0-1.01.0-0.00.90.7
Reaction time omissions2.84.28.20.7-0.2-0.9-0.3-1.8-1.52.1-2.2-0.12.92.92.31.9-2.82.2-2.3-2.32.3-2.42.4-1.12.72.5
Reaction time false alarm rate1.62.23.7-0.4-0.1-1.10.7-1.0-1.81.4-1.51.01.61.61.71.5-1.41.9-1.8-1.81.8-1.81.8-1.11.51.6
Reaction time premature initiation rate0.10.10.60.50.70.1-0.40.40.2-0.20.20.1-0.4-0.4-0.3-0.10.30.1-0.2-0.20.2-0.00.0-0.2-0.5-0.1
Reaction time premature initiations0.10.20.50.50.60.3-0.70.40.1-0.30.2-0.6-0.5-0.5-0.3-0.10.3-0.30.30.3-0.30.4-0.40.1-0.5-0.3
Std. dev. reaction times1.42.65.10.00.1-0.90.0-1.5-1.31.8-1.90.31.71.72.02.3-1.91.7-1.9-1.91.9-2.02.0-1.42.01.9
Reaction time trials completed0.40.71.8-0.4-0.60.4-0.40.20.2-0.40.4-1.1-0.7-0.7-0.7-0.50.6-1.21.41.4-1.41.2-1.20.4-0.7-1.0
Reaction time trials AUC0.40.71.7-0.3-0.30.5-0.40.40.3-0.50.6-1.0-0.9-0.9-0.7-0.50.7-1.11.31.3-1.31.2-1.20.4-0.7-1.0
Run reversals in cocaine runway, females0.70.71.4-0.7-1.2-0.10.10.0-0.1-0.40.4-0.2-0.9-0.9-0.8-1.20.7-0.81.11.1-1.11.1-1.10.5-1.0-1.1
Run reversals in cocaine runway, males0.70.73.4-0.4-0.70.2-0.5-0.00.1-0.30.3-0.4-0.8-0.8-1.5-1.80.9-0.81.01.0-1.01.0-1.00.3-1.0-0.7
Latency to leave start box in cocaine runway0.50.53.6-1.4-1.9-0.91.2-0.9-0.30.3-0.20.90.10.1-0.5-0.20.1-0.30.60.6-0.60.6-0.6-0.2-0.2-0.2
Latency to leave start box in cocaine runway, F0.50.62.4-0.9-1.6-1.01.5-1.1-0.20.6-0.51.10.90.90.20.3-0.70.3-0.1-0.10.1-0.10.1-0.50.60.7
Latency to leave start box in cocaine runway, M1.31.22.9-1.1-0.9-0.10.00.30.1-0.70.70.1-1.7-1.7-1.3-0.91.7-1.01.11.1-1.11.1-1.10.4-1.6-1.6
Std. dev. time between licks in bursts0.50.64.7-1.0-1.3-0.92.2-0.6-0.80.00.11.50.10.1-0.5-0.50.1-0.30.60.6-0.60.6-0.6-0.2-0.20.1
Total sessions with >9 infusions0.40.52.1-0.6-0.7-0.91.2-0.8-1.00.7-0.61.50.20.20.10.0-0.10.7-0.5-0.50.5-0.40.4-0.80.40.7
Short access day 1 total inactive lever presses0.30.41.4-0.5-0.4-0.10.40.40.1-0.40.40.8-1.2-1.2-0.5-0.91.1-0.20.40.4-0.40.3-0.3-0.2-1.0-0.8
Short access day 10 total inactive lever presses0.30.72.3-1.5-0.7-1.30.4-0.7-1.41.0-1.00.9-0.2-0.21.10.60.21.0-0.8-0.80.8-0.90.9-1.00.0-0.1
Short access day 1 total infusions1.21.64.3-0.8-0.7-1.51.7-1.4-0.91.4-1.32.11.11.10.80.6-0.91.4-1.3-1.31.3-1.21.2-1.41.21.6
Short access day 10 total infusions0.40.52.2-1.1-1.1-1.11.3-0.8-1.00.5-0.41.50.10.1-0.3-0.30.30.4-0.1-0.10.1-0.10.1-0.6-0.00.2
Short access total infusions0.10.21.1-0.4-0.4-0.50.7-0.3-0.80.2-0.11.0-0.2-0.2-0.4-0.40.50.3-0.1-0.10.1-0.00.0-0.2-0.10.1
Short access day 1 locomotion0.40.53.4-0.8-0.3-1.01.5-0.4-0.40.4-0.41.8-0.2-0.20.10.10.40.6-0.5-0.50.5-0.40.4-1.1-0.00.4
Short access day 10 total locomotion0.30.52.7-1.3-1.6-1.11.2-1.10.20.7-0.61.20.40.4-0.3-0.5-0.2-0.10.10.1-0.10.1-0.1-0.90.00.3
Short access total locomotion0.50.62.7-1.7-1.4-1.21.3-1.0-0.20.7-0.61.4-0.0-0.0-0.3-0.30.20.1-0.0-0.00.0-0.00.0-1.0-0.10.1
One hour access (0.3 mA shock)0.40.51.31.00.21.0-0.50.61.0-0.80.8-0.70.10.1-1.0-0.8-0.1-0.80.70.7-0.70.5-0.51.1-0.2-0.1
Compulsive drug intake0.10.20.90.50.00.3-0.20.20.9-0.30.3-0.50.60.6-0.1-0.8-0.4-0.50.30.3-0.30.2-0.20.50.10.1
One hour access (shock baseline)0.30.40.90.60.50.9-0.80.60.1-0.70.7-0.8-0.5-0.5-0.9-0.30.5-0.50.60.6-0.60.6-0.61.0-0.5-0.5
Social response proportion0.30.41.3-0.9-0.6-0.60.3-0.8-1.20.8-0.8-0.30.60.61.00.6-0.70.3-0.2-0.20.2-0.20.2-0.70.50.3
Social responses0.81.01.9-0.7-0.20.7-0.80.50.9-0.60.6-1.3-1.0-1.0-0.8-0.90.9-1.41.41.4-1.41.3-1.30.5-1.1-1.4
Social time0.81.12.4-1.5-0.7-1.10.6-1.1-0.21.3-1.30.81.01.01.51.2-0.71.1-1.2-1.21.2-1.01.0-1.30.70.7
Soleus weight0.30.84.42.11.91.3-1.80.90.6-0.40.3-1.0-0.2-0.2-0.20.00.00.3-0.6-0.60.6-0.50.50.50.20.3
Bone: stiffness0.40.61.10.60.20.7-0.20.71.0-0.80.8-0.7-0.6-0.6-0.6-0.50.6-1.01.01.0-1.01.0-1.00.8-0.7-0.6
Tibialis anterior weight2.79.339.46.35.85.0-5.94.02.2-2.92.6-5.0-0.8-0.8-1.4-1.50.6-1.10.70.7-0.70.7-0.73.1-0.5-0.5
Time to tail flick, vehicle, before self-admin1.11.12.3-1.2-1.2-1.41.2-1.1-1.31.1-1.11.20.60.61.21.5-0.71.1-0.9-0.90.9-1.01.0-0.80.80.7
Time to tail flick, vehicle, after self-admin2.63.46.71.01.9-0.5-0.6-0.5-1.11.5-1.60.21.61.62.62.4-1.52.3-2.6-2.62.6-2.62.6-1.22.01.9
Time to tail flick, test, before self-admin1.31.32.1-0.7-0.6-1.31.0-1.3-0.31.2-1.21.50.90.91.10.5-0.91.3-1.4-1.41.4-1.41.4-1.41.11.2
Time to tail flick, test, after self-admin0.50.51.30.61.20.10.10.3-0.40.2-0.20.40.50.50.91.0-0.30.9-1.0-1.01.0-1.11.1-0.40.60.7
Delta time to tail flick, vehicle, before/after SA1.11.05.61.82.40.8-1.30.7-0.40.0-0.2-1.01.01.01.00.6-0.70.9-1.0-1.01.0-0.90.90.10.80.9
Delta time to tail flick, test, before/after SA0.70.72.01.21.41.3-0.71.40.4-1.11.1-0.9-0.6-0.6-0.60.00.5-0.60.60.6-0.60.6-0.61.1-0.6-0.5
Tibia length0.82.29.41.82.22.2-3.11.71.6-1.21.0-2.4-1.7-1.7-0.6-0.61.5-0.90.50.5-0.50.5-0.50.9-0.9-1.3
Ambulatory time before self-admin2.33.47.30.3-0.2-1.11.2-1.6-1.31.6-1.61.12.62.61.82.1-2.71.8-1.9-1.91.9-1.91.9-0.92.62.7
Ambulatory time after self-admin1.21.43.2-0.9-0.7-1.21.8-1.2-0.91.1-1.01.71.31.31.00.9-1.41.2-1.1-1.11.1-1.11.1-0.71.21.5
Bone: tissue strength2.93.05.31.40.72.0-0.51.82.1-2.02.1-1.4-1.4-1.4-1.5-1.31.1-2.12.02.0-2.02.1-2.12.3-1.4-1.4
Total heroin consumption0.10.21.10.71.10.3-0.50.30.8-0.20.2-0.20.10.1-0.00.20.10.0-0.3-0.30.3-0.20.20.40.20.2
Bone: trabecular number1.32.13.1-1.2-0.4-1.50.8-1.5-0.61.6-1.71.21.81.81.61.3-1.31.5-1.6-1.61.6-1.71.7-1.61.51.5
Bone: trabecular spacing1.41.82.81.00.31.3-0.71.21.2-1.61.6-1.2-1.1-1.1-1.6-1.41.1-1.61.51.5-1.51.7-1.71.5-1.3-1.4
Bone: trabecular thickness0.30.41.10.10.1-0.3-0.2-0.5-0.90.7-0.7-0.11.01.00.70.5-1.00.6-0.5-0.50.5-0.60.6-0.30.90.9
Bone: trabecular tissue density0.50.82.5-0.5-0.6-0.80.3-1.0-1.61.0-1.0-0.11.51.50.80.9-1.30.6-0.4-0.40.4-0.40.4-0.81.01.0
Water consumed over 24 hours0.40.62.31.50.30.9-0.50.60.6-0.80.8-0.90.30.3-1.0-0.9-0.5-0.90.90.9-0.90.8-0.80.9-0.00.1
Number of responses in last shaping day2.02.24.8-0.40.1-1.10.6-1.1-2.21.6-1.61.20.90.91.61.9-1.22.0-1.8-1.81.8-1.81.8-1.41.51.7