Hub : Genes

Dnajb14

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Dnajb14 0.05 0.03 2.8e-04 0.03 0.03 0.04 0.03 9.6e-05 6.4e-04 8.1e-05 1.0e-04
2 Adipose gene expression Dnajb14 0.23 0.07 0.0e+00 0.18 0.22 0.23 0.23 2.0e-19 3.0e-24 4.5e-25 6.6e-25
3 PL mRNA stability Dnajb14 0.08 0.04 6.1e-07 0.06 0.04 0.04 0.06 1.5e-07 2.2e-05 1.0e-05 1.1e-06
4 BLA mRNA stability Dnajb14 0.17 0.07 1.8e-07 0.13 0.1 0.11 0.11 1.5e-07 4.1e-06 1.9e-06 1.2e-06
5 NAcc mRNA stability Dnajb14 0.09 0.04 0.0e+00 0.13 0.11 0.11 0.12 9.3e-19 3.4e-16 4.0e-16 1.6e-17
6 NAcc gene expression Dnajb14 0.11 0.04 2.1e-12 0.09 0.1 0.09 0.09 5.2e-13 2.6e-14 7.3e-14 7.5e-13
7 Liver mRNA stability Dnajb14 0.08 0.04 9.0e-08 0.07 0.05 0.05 0.06 1.1e-08 4.3e-06 1.6e-06 8.3e-07
8 Brain mRNA stability Dnajb14 0.08 0.04 3.6e-05 0.06 0.06 0.06 0.05 4.8e-06 3.2e-06 2.3e-06 2.2e-05
9 pVTA mRNA stability Dnajb14 0.05 0.03 1.8e-03 0.04 0.02 0.02 0.03 4.2e-04 6.9e-03 7.3e-03 1.0e-03
10 IC mRNA stability Dnajb14 0.25 0.09 4.6e-08 0.12 0.18 0.17 0.16 1.2e-05 5.9e-08 8.9e-08 4.4e-07
11 Liver gene expression Dnajb14 0.11 0.05 1.4e-11 0.11 0.09 0.09 0.09 7.4e-12 5.2e-10 2.5e-10 1.3e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.11.83.50.90.41.51.91.90.31.91.30.51.8-1.2
Area under the delay curve0.10.20.50.30.70.20.30.30.50.2-0.20.6-0.4-0.0
BMI with tail1.03.514.4-3.8-3.2-1.0-1.3-1.3-1.7-1.8-0.0-1.3-0.2-1.5
BMI without tail1.23.815.0-3.9-3.6-0.9-1.0-1.0-1.9-1.31.0-1.1-0.1-1.8
Body weight1.35.717.1-3.8-4.1-1.7-1.8-1.8-2.7-1.90.2-2.30.1-2.4
Weight adjusted by age0.10.21.1-0.4-0.10.10.30.3-0.30.1-0.51.0-0.7-0.4
Bone surface0.61.02.3-0.5-0.31.11.51.50.61.31.10.11.0-1.0
Bone volume0.61.02.2-0.4-0.51.01.41.40.21.31.5-0.11.0-1.1
Breakpoint value in progressive ratio session0.30.41.30.6-0.10.30.30.3-0.50.7-0.3-0.01.1-1.1
Number of licking bursts0.61.05.4-0.10.2-1.0-1.1-1.1-0.3-0.9-2.3-1.0-0.20.4
Context. condit. distance diff. score0.30.41.41.01.20.30.10.10.60.3-1.10.00.50.4
Locomotion velocity, session 11.41.63.8-1.2-1.2-1.9-1.4-1.4-1.7-1.3-0.6-0.6-1.30.2
Locomotion distance, session 11.82.24.7-1.0-0.3-2.2-1.8-1.8-1.3-1.7-2.0-0.6-1.80.4
Locomotion velocity, session 20.10.10.7-0.00.1-0.30.20.2-0.60.2-0.10.8-0.2-0.2
Locomotion distance, session 22.33.26.7-0.70.1-2.6-2.1-2.1-1.4-2.0-2.0-0.1-2.61.2
Locomotion velocity, session 32.42.75.8-1.4-0.7-2.4-2.0-2.0-0.6-2.0-1.4-1.9-1.91.0
Locomotion distance, session 30.40.51.5-0.60.1-0.8-0.6-0.60.4-0.6-1.2-0.3-0.80.8
Stereotopy head waving bouts, day 31.01.12.4-0.5-1.0-1.6-1.4-1.4-0.8-1.1-0.3-1.2-1.10.3
Stereotopy head waving duration, day 31.41.73.4-1.3-1.4-1.7-1.6-1.6-0.8-1.4-0.4-1.8-0.9-0.2
Locomotion velocity, session 70.60.71.4-0.6-0.6-1.1-1.0-1.0-1.2-1.1-0.6-0.3-0.5-0.4
Locomotion distance, session 70.50.73.2-1.40.2-0.6-0.6-0.60.1-0.7-1.80.3-0.70.1
Stereotopy head waving bouts, day 70.60.71.40.5-0.5-1.2-0.7-0.7-0.4-0.80.5-0.8-1.21.1
Stereotopy head waving duration, day 71.01.22.80.3-0.5-1.6-1.2-1.2-0.4-1.30.2-1.1-1.71.3
Locomotion velocity, session 80.20.30.8-0.10.2-0.6-0.7-0.7-0.3-0.4-0.90.2-0.70.5
Locomotion distance, session 81.52.26.4-0.10.7-2.0-1.8-1.8-1.1-1.6-2.5-0.4-1.50.8
Degree of sensitization distance0.20.20.6-0.30.20.70.30.3-0.10.4-0.20.70.7-0.8
Degree of sensitization stereotypy0.30.41.50.7-0.5-0.6-0.1-0.1-0.4-0.31.2-0.4-0.70.7
Conditioned locomotion0.50.62.80.0-0.30.80.80.80.00.91.70.80.20.2
Cocaine response after cond. corrected0.40.51.91.0-0.20.30.50.5-0.70.81.40.30.8-0.7
Cocaine response after cond. not corrected1.51.74.51.2-0.11.11.31.3-0.81.52.11.51.3-1.2
Cocaine response before conditioning0.20.31.0-0.7-0.20.50.40.40.00.40.61.00.0-0.5
Saline control response1.92.56.1-1.9-0.5-1.7-1.8-1.80.2-2.0-1.3-1.0-2.51.2
Bone: connectivity density1.52.34.81.41.41.82.22.21.12.00.31.01.6-0.5
Bone: cortical apparent density0.10.20.50.7-0.1-0.4-0.2-0.2-0.7-0.2-0.2-0.00.3-0.6
Bone: cortical area1.21.87.5-2.7-2.40.1-0.0-0.0-0.5-0.10.9-1.40.8-1.7
Bone: cortical porosity0.70.71.7-1.3-0.9-0.9-0.8-0.8-0.8-1.10.4-0.5-0.80.5
Bone: cortical porosity1.11.22.9-1.7-1.3-1.1-1.0-1.0-1.1-1.30.6-0.9-0.80.0
Bone: cortical thickness0.91.54.1-1.4-2.00.30.20.2-0.90.31.4-1.31.4-2.0
Bone: cortical thickness1.11.43.8-0.5-1.70.70.40.4-1.60.42.0-0.11.3-1.5
Bone: cortical tissue density0.10.20.50.7-0.0-0.5-0.3-0.3-0.6-0.3-0.4-0.10.2-0.5
Condit. Reinf. active minus inactive responses2.32.65.4-1.0-0.6-2.1-2.3-2.3-1.1-2.0-1.6-1.2-1.50.4
Condit. Reinf. active-inactive response ratio3.53.77.5-1.0-1.4-2.4-2.7-2.7-1.8-2.5-1.4-2.1-1.0-0.4
Condit. Reinf. active responses1.11.43.0-0.4-0.0-1.5-1.7-1.7-0.7-1.4-1.3-0.2-1.50.7
Condit. Reinf. inactive responses0.30.41.70.30.60.60.50.50.70.80.41.3-0.40.6
Incentive salience index mean1.11.32.5-1.1-0.7-1.4-1.6-1.6-0.8-1.5-1.1-0.9-0.90.3
Condit. Reinf. lever presses0.20.30.7-0.8-0.2-0.3-0.3-0.30.3-0.6-0.6-0.7-0.30.8
Condit. Reinf. active minus inactive responses0.40.51.0-0.7-1.00.50.30.30.50.80.7-0.70.7-0.9
Condit. Reinf. active-inactive response ratio0.20.31.10.1-0.40.30.00.00.30.50.2-1.01.0-0.6
Condit. Reinf. active responses0.70.92.8-1.7-1.60.50.50.50.10.80.9-0.40.6-1.4
Condit. Reinf. inactive responses0.81.06.2-2.5-1.6-0.4-0.1-0.1-0.4-0.20.3-0.1-0.6-1.2
Condit. Reinf. lever presses0.70.92.2-0.9-1.21.00.60.6-0.20.91.00.41.2-1.5
Condit. Reinf. lever reinforcers received0.60.92.1-1.3-1.40.70.60.60.00.91.1-0.10.8-1.4
Conditioned reinforcement - actives1.93.35.6-0.20.7-2.2-2.1-2.11.3-1.1-2.4-2.2-2.31.8
Conditioned reinforcement - inactives0.20.31.01.00.7-0.2-0.3-0.30.60.4-0.50.0-0.70.7
Conditioned locomotion0.91.16.50.11.40.50.60.62.60.9-1.1-0.3-0.60.8
Patch foraging indifference point 0 sec0.40.82.30.61.50.40.30.31.40.6-1.50.7-0.30.6
Patch foraging indifference point AUC0.40.52.5-1.6-1.10.2-0.0-0.00.20.00.1-0.40.5-1.2
Delay disc. indifference point, 0s delay0.91.05.40.01.20.60.70.72.30.6-0.8-0.2-0.41.0
Delay disc. indifference point, 16s delay0.30.31.1-1.00.1-0.4-0.4-0.40.2-0.5-0.9-0.2-0.6-0.2
Delay disc. indifference point, 2s delay0.80.93.80.81.20.80.80.82.00.50.20.6-0.51.1
Delay disc. indifference point, 24s delay0.70.81.30.91.11.11.11.10.71.00.41.00.20.6
Delay disc. indifference point, 4s delay0.60.61.90.80.70.81.01.00.00.80.31.40.6-0.3
Delay disc. indifference point, 8s delay0.50.62.3-0.30.1-1.0-0.9-0.9-0.4-0.9-0.40.1-1.50.1
Indifference point function ln k0.50.91.70.10.4-1.1-1.1-1.1-0.8-1.2-1.3-0.1-1.10.8
Indifference point function log k0.50.91.70.10.4-1.1-1.1-1.1-0.8-1.2-1.3-0.1-1.10.8
Patch foraging total patch changes 0 sec0.30.62.40.31.30.30.20.21.20.5-1.60.6-0.30.4
Patch foraging total patch changes 12 sec0.20.20.4-0.40.10.60.50.50.50.6-0.50.40.5-0.6
Patch foraging total patch changes 18 sec0.30.42.40.30.90.1-0.0-0.00.8-0.0-1.5-0.1-0.00.5
Patch foraging total patch changes 24 sec0.61.12.6-1.0-0.2-1.2-1.1-1.10.6-1.1-1.6-1.2-1.20.6
Patch foraging total patch changes 6 sec0.71.12.0-0.30.51.41.31.31.21.2-0.60.71.4-0.8
Patch foraging time to switch 0 sec0.40.95.22.31.30.30.50.50.60.60.20.0-0.01.1
Patch foraging water rate 0 sec0.20.52.5-1.6-0.90.10.00.0-0.7-0.3-0.1-0.10.7-1.0
Patch foraging water rate 12 sec0.81.73.2-1.6-1.5-1.5-1.5-1.5-1.5-1.8-0.2-1.2-0.5-0.4
Patch foraging water rate 18 sec0.30.41.3-1.0-0.90.10.20.2-0.7-0.1-0.2-0.41.1-0.9
Patch foraging water rate 24 sec0.60.81.8-1.2-0.5-0.8-1.0-1.0-0.9-1.1-1.3-0.6-0.0-0.3
Patch foraging water rate 6 sec2.23.210.4-1.3-2.0-1.9-1.9-1.9-3.2-2.2-0.5-0.7-0.1-1.5
Seeking ratio, delayed vs. immediate footshock2.63.25.82.11.62.12.22.20.92.11.42.41.00.5
Distance traveled before self-admin0.40.53.9-0.4-0.2-0.0-0.0-0.00.6-0.5-0.5-0.9-0.52.0
Distance traveled after self-admin0.30.31.20.30.3-0.3-0.3-0.30.5-0.5-1.1-0.3-0.41.1
Extensor digitorum longus weight2.811.132.9-4.7-5.7-2.7-2.5-2.5-3.8-2.82.1-3.8-0.7-2.4
Bone: elastic displacement0.60.72.4-1.5-1.2-0.5-0.7-0.7-0.6-0.90.5-1.0-0.0-0.2
Bone: elastic work1.11.43.8-1.5-2.0-0.3-0.6-0.6-1.5-0.91.0-1.20.9-1.4
Bone: endosteal estimation0.30.64.3-2.1-0.9-0.2-0.3-0.30.4-0.4-0.4-0.5-0.60.1
Bone: endosteal perimeter0.61.46.1-2.5-1.1-0.8-1.0-1.00.5-1.1-0.7-1.3-1.10.6
Epididymis fat weight0.62.17.8-2.8-1.7-1.2-1.2-1.2-0.2-1.8-1.2-1.4-1.00.0
Delta time in closed arm before/after self-admin1.41.32.8-0.4-0.4-1.7-1.6-1.6-0.6-0.9-1.3-1.1-1.40.3
Delta time in open arm before/after self-admin1.61.63.8-0.70.0-1.4-1.4-1.40.8-1.4-0.5-1.4-2.01.6
Diff in mean of infusions in LGA sessions1.41.74.52.11.01.21.31.3-0.21.6-0.11.31.8-0.9
Delay discount exponential model param0.20.20.8-0.6-0.7-0.4-0.4-0.4-0.3-0.3-0.1-0.90.20.1
Extinction: sum of active levers before priming1.01.12.70.8-0.41.01.01.0-1.21.01.30.91.6-1.1
Active lever presses in extinction session 60.80.82.21.31.50.60.60.61.10.9-1.20.80.4-0.0
Bone: final force0.20.30.9-1.0-0.8-0.2-0.5-0.5-0.3-0.4-0.4-0.70.3-0.5
Bone: final moment0.20.31.0-1.0-0.80.0-0.2-0.2-0.4-0.1-0.0-0.50.5-0.7
Food consumed during 24 hour testing period0.71.04.2-1.1-1.5-0.9-0.4-0.4-2.0-0.80.5-0.30.1-1.2
Glucose0.71.02.9-1.7-1.7-0.0-0.3-0.3-1.5-0.60.40.30.6-1.5
Heart weight1.01.66.8-2.6-2.1-0.5-0.7-0.7-0.6-0.70.7-1.3-0.2-1.4
Delay discount hyperbolic model param0.30.30.9-0.7-0.8-0.4-0.5-0.5-0.6-0.4-0.0-1.00.20.0
Intermittent access intake day 1-15 change0.20.51.10.80.80.70.70.70.90.7-0.30.30.01.0
Intermittent access intake escalation0.61.21.81.01.21.31.31.31.31.2-0.20.70.41.0
Intermittent access intake escalation 21.21.44.02.01.11.41.51.50.61.10.40.51.30.7
Intermitt. access day 1 inactive lever presses0.10.31.1-0.7-0.6-0.3-0.3-0.3-0.8-0.10.40.4-0.3-1.0
Intermitt. access day 15 inactive lever presses0.40.93.7-1.9-1.6-0.4-0.5-0.5-1.2-0.60.6-0.2-0.5-0.7
Intermitt. access escalation Index0.10.21.3-0.5-0.6-0.0-0.2-0.2-0.4-0.11.1-0.3-0.2-0.1
Intermittent access day 1 total infusions0.81.32.6-1.5-1.6-1.1-1.2-1.2-1.6-1.0-0.2-0.3-0.4-1.1
Intermittent access day 15 total infusions0.00.10.2-0.5-0.40.20.10.1-0.30.1-0.40.20.2-0.1
Intermittent access terminal intake (last 3 days)0.20.30.8-0.3-0.3-0.6-0.7-0.7-0.7-0.7-0.9-0.4-0.20.3
Intermittent access total infusions0.70.81.3-1.1-1.0-1.0-1.1-1.1-1.1-0.8-0.8-0.5-0.4-0.3
Intermittent access day 1 locomotion0.70.83.5-1.9-1.3-0.7-0.8-0.8-0.4-0.7-0.6-0.8-0.4-0.6
Intermittent access day 15 total locomotion0.30.62.2-0.50.40.80.70.71.50.1-1.0-0.2-0.01.3
Intermittent access total locomotion0.10.10.5-0.7-0.50.30.30.30.20.2-0.5-0.40.20.0
Intermittent access standard deviation0.00.10.3-0.4-0.20.0-0.1-0.10.30.1-0.4-0.50.30.0
Left kidney weight0.52.48.0-2.5-2.8-0.9-0.8-0.8-1.8-1.20.7-1.50.1-1.7
Right kidney weight0.62.67.5-2.7-2.6-1.0-1.2-1.2-1.7-1.40.6-1.7-0.1-1.5
Cocaine induced anxiety0.20.21.0-0.90.20.10.10.11.00.4-0.6-0.3-0.1-0.2
Post-drug Anxiety0.30.42.1-0.50.50.40.30.31.50.7-0.70.1-0.20.3
Baseline Anxiety0.10.10.50.6-0.3-0.1-0.3-0.3-0.70.10.40.10.2-0.2
Tail length0.10.52.0-0.6-1.4-0.4-0.1-0.1-0.50.00.9-1.00.2-1.0
Length with tail0.41.65.1-1.2-2.3-0.9-0.8-0.8-1.7-0.60.6-1.30.4-1.8
Length without tail0.20.71.6-0.9-0.9-0.9-0.8-0.8-0.5-0.8-0.7-1.3-0.1-0.8
Times rat made contact with spout1.51.73.71.40.20.91.31.3-1.31.41.01.41.9-1.5
Lifetime Intake0.91.11.8-1.3-0.9-1.3-1.3-1.3-1.0-1.0-1.0-0.6-0.7-0.2
Liver weight, left0.50.81.8-0.7-0.1-0.8-0.8-0.80.6-1.1-1.3-1.3-0.90.7
Liver weight, right0.30.52.10.00.2-0.4-0.4-0.40.8-0.5-1.4-1.50.00.6
Locomotor activity0.20.41.3-0.7-0.40.50.30.3-0.40.80.30.80.3-1.1
Locomotor testing distance0.30.62.2-1.1-0.90.20.10.1-1.00.50.70.90.1-1.5
Locomotor testing rearing1.12.27.50.1-0.90.90.90.9-2.01.20.92.21.8-2.7
Locomotion in novel chamber5.26.610.92.42.33.33.33.31.83.11.42.92.30.2
Locomotion in novel chamber post-restriction0.61.12.81.3-0.30.50.80.8-1.11.11.71.40.8-0.9
Fecal boli incidents, locomotor time 10.20.41.20.20.1-0.9-0.8-0.80.2-0.1-0.7-0.1-1.10.4
Change in fecal boli incidents, locomotor task0.50.51.5-0.7-0.60.60.50.5-1.2-0.30.51.20.7-0.5
Time >=10cm from walls, locomotor time 11.31.42.60.60.91.61.61.61.11.30.01.01.6-0.6
Bouts of movement, locomotor time 10.60.71.70.70.31.00.90.9-0.00.90.70.71.3-0.9
Total resting periods, locomotor time 10.20.20.70.30.10.50.40.4-0.10.50.40.50.8-0.8
Rest time, locomotor task time 10.10.20.50.3-0.5-0.3-0.4-0.40.10.20.7-0.4-0.4-0.4
Distance moved, locomotor task time 10.10.20.6-0.8-0.20.20.40.4-0.4-0.10.20.60.3-0.5
Vertical activity count, locomotor time 10.10.20.4-0.50.40.50.60.60.20.2-0.10.50.40.0
Time >=10cm from walls, locomotor time 21.42.15.5-1.9-1.1-1.5-1.6-1.6-0.7-2.4-0.1-1.3-1.41.1
Bouts of movement, locomotor time 20.50.82.40.71.11.11.01.01.50.70.50.60.20.7
Total resting periods, locomotor time 20.50.92.30.71.11.21.11.11.50.80.50.80.20.6
Rest time, locomotor task time 20.91.12.40.50.01.31.31.30.61.61.41.10.7-0.7
Distance moved, locomotor task time 20.60.71.9-0.30.4-1.0-0.9-0.9-0.0-1.4-0.7-0.8-0.81.0
Vertical activity count, locomotor time 20.20.21.00.00.5-0.3-0.2-0.20.0-0.7-0.2-0.5-0.21.0
Light reinforcement 10.92.19.9-3.1-1.8-1.3-1.1-1.1-1.2-1.1-1.0-0.8-1.0-0.9
Light reinforcement 20.20.31.1-0.9-0.80.20.20.2-0.50.10.5-0.10.1-1.0
Bone: marrow area0.20.53.8-1.9-0.8-0.1-0.2-0.20.4-0.3-0.4-0.4-0.50.1
Bone: maximum diameter0.51.06.5-2.5-1.50.20.40.40.40.10.2-0.70.2-0.9
Bone: maximum force0.30.62.2-1.5-0.8-0.4-0.4-0.40.0-0.4-0.7-1.40.2-0.5
Bone: maximum moment0.30.42.2-1.5-0.8-0.0-0.1-0.1-0.0-0.1-0.3-1.00.5-0.8
Mean time between licks in bursts0.10.21.40.20.6-0.1-0.2-0.20.6-0.1-1.2-0.2-0.00.2
Mean num. licks in bursts1.72.68.70.7-0.21.61.81.8-0.61.62.91.81.4-1.3
Cd content in liver0.10.10.40.1-0.2-0.3-0.2-0.20.30.0-0.5-0.70.5-0.3
Co content in liver4.65.39.2-2.9-1.8-2.6-3.0-3.0-1.1-3.0-1.8-2.0-2.20.4
Cu content in liver1.31.63.51.81.91.01.11.11.01.4-0.81.41.00.7
Fe content in liver0.40.53.60.00.60.30.40.41.90.1-0.0-0.2-0.50.9
K content in liver1.11.13.40.81.01.31.21.21.00.5-0.01.90.70.7
Mg content in liver0.40.41.40.80.90.40.30.30.40.0-0.81.20.30.8
Mn content in liver0.91.01.60.2-0.41.11.11.1-0.11.11.31.21.3-1.1
Na content in liver0.30.30.9-0.10.30.70.90.90.50.4-0.00.60.4-0.3
Rb content in liver0.91.02.60.50.5-1.0-0.8-0.80.8-0.8-1.6-0.8-1.21.6
Se content in liver0.10.10.30.30.00.30.40.40.5-0.10.60.6-0.10.3
Sr content in liver0.90.81.9-0.1-0.91.20.80.8-0.60.61.41.10.6-1.2
Zn content in liver14.616.229.54.95.44.74.14.14.34.0-1.34.43.31.5
Bone: minimum diameter1.62.910.5-3.2-2.8-1.2-1.4-1.4-1.3-1.50.2-1.8-0.5-1.1
Time in familiar zone, hab. session 10.50.51.4-0.10.3-0.8-0.5-0.50.3-0.3-0.9-1.2-0.81.0
Time in novel zone, hab. session 10.20.20.8-0.3-0.20.70.30.30.50.30.90.50.1-0.4
Total zone transitions, hab. session 12.83.98.6-1.3-0.6-2.9-2.5-2.5-1.3-2.4-1.7-1.5-2.60.8
Total locomotion distance, hab. session 10.50.81.7-0.30.2-1.3-0.9-0.9-0.3-0.9-1.3-1.0-1.10.6
Locomotion velocity, hab. session 10.30.40.9-0.30.0-1.0-0.6-0.6-0.7-0.7-1.0-0.6-0.60.2
Time in familiar zone, hab. session 21.81.93.8-0.3-1.11.61.41.4-0.51.52.00.61.8-1.7
Time in novel zone, hab. session 21.31.33.00.61.2-1.1-1.0-1.00.9-0.8-1.7-0.3-1.51.6
Total zone transitions, hab. session 21.92.55.2-1.3-0.5-2.3-1.9-1.9-1.0-1.8-1.9-1.1-1.90.5
Total locomotion distance, hab. session 20.20.30.7-0.6-0.4-0.6-0.5-0.5-0.8-0.2-0.5-0.2-0.2-0.6
Locomotion velocity, hab. session 20.10.20.4-0.4-0.2-0.6-0.4-0.4-0.6-0.1-0.6-0.1-0.3-0.4
Novel to familiar place preference ratio0.10.10.50.10.0-0.00.40.4-0.7-0.00.00.60.2-0.5
Novelty place preference0.20.20.8-0.1-0.10.20.50.5-0.80.10.20.90.3-0.7
Time in novel zone, NPP test0.30.30.9-0.2-0.20.20.50.5-0.90.20.41.00.4-0.8
Total zone transitions, NPP test1.42.14.2-1.5-1.0-2.0-1.7-1.7-1.5-1.7-1.4-1.0-1.30.0
Total locomotion distance, NPP test0.10.10.5-0.1-0.1-0.4-0.3-0.3-0.6-0.0-0.7-0.40.3-0.3
Locomotion velocity, NPP test0.10.20.7-0.0-0.2-0.3-0.2-0.2-0.90.1-0.6-0.20.6-0.7
Intraocular pressure0.10.21.0-0.10.10.1-0.1-0.11.00.20.4-0.6-0.40.5
Delta distance traveled before/after self-admin0.30.31.20.30.5-0.6-0.6-0.60.1-0.5-1.10.3-0.4-0.6
Delta ambulatory time before/after self-admin0.20.21.10.30.4-0.4-0.3-0.30.0-0.0-0.80.40.0-1.0
Parametrial fat weight0.10.31.00.30.50.60.30.31.0-0.1-0.7-0.40.21.0
Pavlov. Cond. lever latency0.60.82.6-0.4-1.2-0.6-0.8-0.8-1.6-0.80.9-0.30.1-1.1
Pavlov. Cond. magazine entry latency0.50.71.5-0.4-0.0-0.8-1.0-1.00.4-0.9-0.5-0.5-1.21.2
Pavlov. Cond. change in total contacts0.60.61.70.81.1-0.7-0.5-0.50.5-0.3-1.30.3-0.91.1
Pavlov. Cond. index score0.30.30.90.60.80.40.40.40.90.4-0.40.40.01.0
Pavlov. Cond. latency score0.40.51.40.71.10.50.60.61.20.6-0.50.50.01.0
Pavlov. Cond. lever contacts0.40.51.70.20.80.50.70.71.30.6-0.70.10.20.8
Pavlov. Cond. magazine entry number0.70.91.60.10.01.31.31.30.11.20.80.91.2-1.1
Pavlov. Cond. intertrial magazine entries0.20.21.1-0.20.40.20.10.11.00.3-0.7-0.5-0.10.1
Pavlov. Cond. lever-magazine prob. diff.0.30.40.70.80.90.60.60.60.60.6-0.20.80.20.8
Pavlov. Cond. response bias0.70.92.2-0.10.5-0.9-0.9-0.90.7-0.8-1.3-0.9-1.01.5
Pavlov. Cond. lever latency0.60.92.21.51.40.90.90.90.60.80.31.10.10.8
Pavlov. Cond. magazine entry latency0.10.10.20.50.20.2-0.3-0.30.30.2-0.20.0-0.2-0.1
Pavlov. Cond. change in total contacts0.10.10.4-0.6-0.30.1-0.1-0.10.20.1-0.4-0.20.3-0.6
Pavlov. Cond. index score0.10.10.2-0.4-0.40.30.10.10.40.40.1-0.50.3-0.5
Pavlov. Cond. latency score0.10.10.50.20.10.30.10.10.70.5-0.2-0.30.3-0.1
Pavlov. Cond. lever contacts0.70.92.7-1.6-1.6-0.7-0.8-0.8-0.6-0.7-0.0-1.30.0-1.0
Pavlov. Cond. magazine entry number0.00.10.2-0.10.0-0.20.20.2-0.5-0.30.10.3-0.10.3
Pavlov. Cond. intertrial magazine entries0.71.01.8-1.0-1.00.91.21.2-0.40.91.30.21.1-1.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.3-0.30.30.10.10.50.40.1-0.50.4-0.5
Pavlov. Cond. response bias0.91.33.6-1.9-1.8-0.9-1.0-1.0-0.7-0.90.1-1.3-0.3-1.0
Time in closed arm before self-admin0.20.20.80.50.9-0.1-0.2-0.20.2-0.6-0.8-0.20.10.1
Time in closed arm after self-admin0.40.41.81.01.30.20.20.20.20.2-1.20.40.5-0.2
Time in open arm before self-admin1.92.15.6-0.3-1.41.11.11.1-1.61.21.81.31.7-2.4
Time in open arm after self-admin0.30.40.8-0.7-0.8-0.6-0.6-0.6-0.0-0.40.6-0.6-0.90.3
Bone: periosteal estimation0.71.58.1-2.8-2.2-0.2-0.2-0.2-0.5-0.30.4-1.20.1-1.1
Bone: periosteal perimeter1.01.78.9-3.0-2.1-0.7-0.7-0.7-0.2-0.80.3-1.5-0.7-0.6
Bone: post-yield work0.91.33.7-0.21.5-0.2-0.2-0.21.9-0.4-1.9-0.8-1.01.7
Progressive ratio test 1 active lever presses2.22.75.2-1.6-1.7-2.0-2.3-2.3-2.1-1.7-0.6-0.6-1.3-0.7
Progressive ratio test 1 breakpoint2.12.54.8-1.5-1.5-2.0-2.2-2.2-2.0-1.6-0.7-0.5-1.2-0.7
Progressive ratio test 1 inactive lever presses0.40.62.0-0.5-0.90.0-0.1-0.1-1.40.30.81.1-0.0-1.0
Progressive ratio test 2 active lever presses1.11.32.6-0.6-1.5-1.3-1.5-1.5-1.6-1.0-0.0-1.1-0.5-0.4
Progressive ratio test 2 breakpoint0.91.02.7-0.5-1.4-1.0-1.2-1.2-1.6-0.80.1-0.8-0.2-0.6
Progressive ratio test 2 inactive lever presses0.30.61.2-0.3-0.6-1.0-1.1-1.1-0.5-0.4-0.4-0.9-0.90.3
Incentive Sensitization - Responses0.40.62.61.20.70.20.10.10.90.2-0.4-1.0-0.11.6
Incentive Sensitization - Breakpoint0.40.52.01.20.50.40.30.30.70.3-0.1-0.80.21.4
Sum of active levers in priming session hrs 5-63.83.66.92.41.02.32.32.3-0.22.01.41.82.6-0.7
Progressive ratio0.50.84.1-0.7-1.00.70.80.8-0.60.12.00.60.5-0.4
Food seeking constrained by brief footshock0.50.61.7-1.1-1.3-0.2-0.1-0.1-1.0-0.00.2-0.70.8-1.1
Seeking ratio, punishment vs. effort0.20.31.80.50.5-0.5-0.6-0.6-0.40.1-1.4-0.30.1-0.2
Retroperitoneal fat weight0.20.93.6-1.8-1.90.20.10.1-0.7-0.40.7-0.70.6-1.0
Reaction time number correct0.20.31.0-0.4-0.70.30.10.1-1.00.20.70.30.6-0.8
Reaction time mean minus median0.20.52.71.60.50.60.30.30.40.91.10.10.3-0.1
Reaction time mean minus median AUC0.30.83.92.00.70.80.60.60.41.11.10.50.6-0.2
Reaction time num false alarms1.11.56.0-1.2-0.1-1.6-1.2-1.20.5-1.2-0.9-0.6-2.41.1
Reaction time num false alarms AUC1.32.06.4-1.7-0.5-1.8-1.5-1.50.3-1.5-0.6-1.1-2.51.2
Reaction time trials correct on left0.20.31.0-0.4-0.70.30.10.1-1.00.20.70.30.6-0.8
Reaction time trials on left0.20.30.9-0.3-0.70.40.10.1-1.00.30.80.40.6-0.8
Reaction time mean0.81.24.80.8-0.40.90.80.8-0.71.22.21.00.9-1.5
Reaction time mean AUC0.71.25.10.7-0.60.70.60.6-0.91.02.21.00.8-1.5
Median of all reaction times0.91.35.00.2-0.90.70.70.7-1.21.02.21.00.9-1.8
Reaction time omissions0.81.22.91.71.21.20.80.81.21.51.40.80.40.3
Reaction time false alarm rate0.91.34.6-0.90.1-1.4-1.0-1.00.8-1.1-0.7-0.8-2.11.2
Reaction time premature initiation rate2.12.98.2-2.9-1.8-1.9-1.7-1.7-0.7-2.2-0.7-1.6-1.7-0.0
Reaction time premature initiations1.73.18.7-2.9-2.2-1.8-1.8-1.8-1.3-2.1-0.3-1.6-1.5-0.3
Std. dev. reaction times0.50.93.71.90.91.00.70.70.81.21.20.50.50.1
Reaction time trials completed0.20.30.9-0.3-0.70.40.10.1-1.00.30.80.40.6-0.8
Reaction time trials AUC0.10.30.8-0.5-0.80.3-0.0-0.0-0.90.20.60.20.5-0.8
Run reversals in cocaine runway, females0.60.62.20.90.20.80.40.4-0.90.50.51.50.8-0.8
Run reversals in cocaine runway, males0.90.94.01.0-0.3-0.1-0.1-0.1-2.0-0.11.01.20.6-1.3
Latency to leave start box in cocaine runway0.40.51.1-0.20.60.60.90.90.60.5-1.01.00.10.3
Latency to leave start box in cocaine runway, F0.50.62.9-0.50.5-0.4-0.1-0.11.0-0.3-1.7-0.4-0.80.8
Latency to leave start box in cocaine runway, M2.12.04.90.70.51.81.81.8-0.21.60.72.21.5-0.8
Std. dev. time between licks in bursts0.91.36.30.21.3-0.9-0.7-0.70.2-1.0-2.50.3-0.91.5
Total sessions with >9 infusions2.12.64.6-1.5-0.1-2.1-2.1-2.1-0.3-1.7-2.2-0.7-2.10.8
Short access day 1 total inactive lever presses0.30.41.4-0.50.0-0.8-0.9-0.9-0.5-0.7-1.2-0.1-0.50.3
Short access day 10 total inactive lever presses0.30.71.70.41.30.60.60.61.20.7-0.21.2-0.50.8
Short access day 1 total infusions2.23.06.7-1.00.6-2.0-2.0-2.00.4-1.7-2.6-1.2-2.21.8
Short access day 10 total infusions0.81.11.9-0.9-0.5-1.4-1.4-1.4-1.2-1.2-0.90.2-1.10.0
Short access total infusions1.31.63.0-1.2-0.4-1.7-1.7-1.7-1.1-1.3-1.4-0.0-1.50.0
Short access day 1 locomotion1.82.37.7-1.30.6-1.7-1.7-1.70.7-0.9-2.8-1.2-1.71.0
Short access day 10 total locomotion0.10.20.40.10.50.30.40.40.20.6-0.50.40.3-0.5
Short access total locomotion0.30.41.5-1.10.4-0.00.00.00.70.3-1.20.5-0.5-0.1
One hour access (0.3 mA shock)0.10.10.3-0.1-0.40.40.20.2-0.00.5-0.0-0.10.5-0.6
Compulsive drug intake0.81.02.4-0.3-0.51.61.21.2-0.10.71.40.61.2-0.8
One hour access (shock baseline)0.10.20.50.0-0.3-0.6-0.6-0.6-0.7-0.4-0.3-0.1-0.30.1
Social response proportion0.40.41.90.50.90.5-0.1-0.10.6-0.50.10.7-0.41.4
Social responses0.60.81.8-0.2-0.31.31.11.1-0.10.80.61.11.3-0.5
Social time1.01.42.31.41.31.51.41.41.51.00.30.80.90.9
Soleus weight0.72.17.0-2.7-2.2-1.2-1.2-1.2-1.1-1.50.3-1.3-1.1-0.3
Bone: stiffness0.40.62.4-1.5-1.1-0.3-0.3-0.3-0.6-0.3-0.3-0.80.3-1.2
Tibialis anterior weight3.511.739.6-4.8-6.3-2.2-1.7-1.7-4.5-2.23.2-2.90.1-3.5
Time to tail flick, vehicle, before self-admin0.40.41.00.80.8-0.2-0.1-0.10.90.1-0.60.1-0.81.0
Time to tail flick, vehicle, after self-admin0.60.84.0-1.00.30.20.20.22.0-0.0-0.1-0.8-0.81.7
Time to tail flick, test, before self-admin0.50.51.6-0.20.50.80.80.81.30.80.70.40.00.2
Time to tail flick, test, after self-admin0.10.10.5-0.00.3-0.1-0.1-0.10.7-0.4-0.5-0.5-0.20.3
Delta time to tail flick, vehicle, before/after SA0.60.63.7-1.9-0.5-0.2-0.3-0.30.7-0.6-0.5-0.7-0.70.7
Delta time to tail flick, test, before/after SA0.60.61.40.3-0.4-0.9-0.9-0.9-0.7-1.2-1.0-1.0-0.20.3
Tibia length0.61.66.0-1.3-2.4-0.10.10.1-1.00.11.7-0.90.7-2.1
Ambulatory time before self-admin0.30.54.2-0.0-0.0-0.0-0.1-0.10.4-0.5-0.5-0.6-0.52.1
Ambulatory time after self-admin0.91.03.10.60.9-0.5-0.5-0.51.3-0.5-1.7-0.6-1.01.8
Bone: tissue strength0.20.31.0-0.7-0.3-0.4-0.4-0.40.1-0.6-0.4-1.00.2-0.5
Total heroin consumption0.50.61.30.4-0.10.90.90.90.30.80.9-0.01.1-0.8
Bone: trabecular number0.30.51.80.40.90.50.70.71.40.80.2-0.2-0.10.3
Bone: trabecular spacing0.81.02.50.2-0.21.31.01.0-0.51.00.71.51.6-1.0
Bone: trabecular thickness0.20.20.70.4-0.5-0.6-0.2-0.2-0.8-0.40.4-0.4-0.4-0.1
Bone: trabecular tissue density0.30.41.30.6-0.3-0.8-0.6-0.6-1.1-0.70.50.2-0.4-0.3
Water consumed over 24 hours0.20.31.30.4-0.4-0.5-0.1-0.1-1.10.10.2-0.20.5-0.9
Number of responses in last shaping day3.74.07.3-1.8-0.8-2.5-2.5-2.5-0.4-2.4-1.6-1.6-2.71.7