Hub : Genes

Dnajb14

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Dnajb14 0.05 0.03 2.8e-04 0.03 0.03 0.04 0.03 9.6e-05 6.4e-04 8.1e-05 9.4e-05
2 Adipose gene expression Dnajb14 0.23 0.07 0.0e+00 0.18 0.22 0.23 0.23 2.0e-19 3.0e-24 4.4e-25 7.1e-25
3 PL mRNA stability Dnajb14 0.08 0.04 6.1e-07 0.06 0.04 0.04 0.06 1.5e-07 2.2e-05 1.0e-05 1.2e-06
4 BLA mRNA stability Dnajb14 0.17 0.07 1.8e-07 0.13 0.1 0.11 0.11 1.5e-07 4.1e-06 1.9e-06 1.3e-06
5 NAcc mRNA stability Dnajb14 0.09 0.04 0.0e+00 0.13 0.11 0.11 0.12 9.3e-19 3.4e-16 4.2e-16 1.7e-17
6 NAcc gene expression Dnajb14 0.11 0.04 2.1e-12 0.09 0.1 0.09 0.09 5.2e-13 2.6e-14 6.8e-14 7.0e-13
7 Liver mRNA stability Dnajb14 0.08 0.04 9.0e-08 0.07 0.05 0.05 0.06 1.1e-08 4.3e-06 1.6e-06 8.2e-07
8 Brain mRNA stability Dnajb14 0.08 0.04 3.6e-05 0.06 0.06 0.06 0.05 4.8e-06 3.2e-06 2.3e-06 2.0e-05
9 pVTA mRNA stability Dnajb14 0.05 0.03 1.8e-03 0.04 0.02 0.02 0.03 4.2e-04 6.9e-03 7.3e-03 9.0e-04
10 IC mRNA stability Dnajb14 0.25 0.09 4.6e-08 0.12 0.18 0.17 0.16 1.2e-05 5.9e-08 8.9e-08 4.2e-07
11 Liver gene expression Dnajb14 0.11 0.05 1.4e-11 0.11 0.09 0.09 0.09 7.4e-12 5.2e-10 2.5e-10 1.3e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.01.83.5-0.9-0.4-1.5-1.9-1.90.3-1.9-1.3-0.51.81.2
Area under the delay curve0.10.20.5-0.3-0.7-0.2-0.3-0.30.5-0.20.2-0.6-0.40.0
BMI with tail1.03.514.43.83.21.01.31.3-1.71.80.01.3-0.21.5
BMI without tail0.73.815.03.93.60.91.01.0-1.91.3-1.01.1-0.11.8
Body weight1.35.717.13.84.11.71.81.8-2.71.9-0.22.30.12.4
Weight adjusted by age0.10.21.10.40.1-0.1-0.3-0.3-0.3-0.10.5-1.0-0.70.4
Bone surface0.51.02.30.50.3-1.1-1.5-1.50.6-1.3-1.1-0.11.01.0
Bone volume0.51.02.20.40.5-1.0-1.4-1.40.2-1.3-1.50.11.01.1
Breakpoint value in progressive ratio session0.20.41.3-0.60.1-0.3-0.3-0.3-0.5-0.70.30.01.11.1
Number of licking bursts0.31.05.40.1-0.21.01.11.1-0.30.92.31.0-0.2-0.4
Context. condit. distance diff. score0.30.41.3-1.0-1.2-0.3-0.1-0.10.6-0.31.1-0.00.5-0.4
Locomotion velocity, session 11.41.63.81.21.21.91.41.4-1.71.30.60.6-1.3-0.2
Locomotion distance, session 11.72.24.71.00.32.21.81.8-1.31.72.00.6-1.8-0.4
Locomotion velocity, session 20.10.10.70.0-0.10.3-0.2-0.2-0.6-0.20.1-0.8-0.20.2
Locomotion distance, session 22.33.26.70.7-0.12.62.12.1-1.42.02.00.1-2.6-1.2
Locomotion velocity, session 32.42.75.81.40.72.42.02.0-0.62.01.41.9-1.9-1.0
Locomotion distance, session 30.40.51.50.6-0.10.80.60.60.40.61.20.3-0.8-0.8
Stereotopy head waving bouts, day 30.91.12.40.51.01.61.41.4-0.81.10.31.2-1.1-0.3
Stereotopy head waving duration, day 31.31.73.41.31.41.71.61.6-0.81.40.41.8-0.90.2
Locomotion velocity, session 70.60.71.40.60.61.11.01.0-1.21.10.60.3-0.50.4
Locomotion distance, session 70.50.73.21.4-0.20.60.60.60.10.71.8-0.3-0.7-0.1
Stereotopy head waving bouts, day 70.60.71.4-0.50.51.20.70.7-0.40.8-0.50.8-1.2-1.1
Stereotopy head waving duration, day 71.01.22.8-0.30.51.61.21.2-0.41.3-0.21.1-1.7-1.3
Locomotion velocity, session 80.20.30.80.1-0.20.60.70.7-0.30.40.9-0.2-0.7-0.5
Locomotion distance, session 81.52.26.40.1-0.72.01.81.8-1.11.62.50.4-1.5-0.8
Degree of sensitization distance0.20.20.60.3-0.2-0.7-0.3-0.3-0.1-0.40.2-0.70.70.8
Degree of sensitization stereotypy0.30.41.5-0.70.50.60.10.1-0.40.3-1.20.4-0.7-0.7
Conditioned locomotion0.50.62.8-0.00.3-0.8-0.8-0.80.0-0.9-1.7-0.80.2-0.2
Cocaine response after cond. corrected0.40.51.9-1.00.2-0.3-0.5-0.5-0.7-0.8-1.4-0.30.80.7
Cocaine response after cond. not corrected1.21.74.5-1.20.1-1.1-1.3-1.3-0.8-1.5-2.1-1.51.31.2
Cocaine response before conditioning0.20.31.00.70.2-0.5-0.4-0.40.0-0.4-0.6-1.00.00.5
Saline control response1.82.56.11.90.51.71.81.80.22.01.31.0-2.5-1.2
Bone: connectivity density1.52.34.8-1.4-1.4-1.8-2.2-2.21.1-2.0-0.3-1.01.60.5
Bone: cortical apparent density0.10.20.5-0.70.10.40.20.2-0.70.20.20.00.30.6
Bone: cortical area1.11.87.52.72.4-0.10.00.0-0.50.1-0.91.40.81.7
Bone: cortical porosity0.60.71.71.30.90.90.80.8-0.81.1-0.40.5-0.8-0.5
Bone: cortical porosity1.11.22.91.71.31.11.01.0-1.11.3-0.60.9-0.8-0.0
Bone: cortical thickness0.91.54.11.42.0-0.3-0.2-0.2-0.9-0.3-1.41.31.42.0
Bone: cortical thickness1.11.43.80.51.7-0.7-0.4-0.4-1.6-0.4-2.00.11.31.5
Bone: cortical tissue density0.10.20.5-0.70.00.50.30.3-0.60.30.40.10.20.5
Condit. Reinf. active minus inactive responses2.32.65.41.00.62.12.32.3-1.12.01.61.2-1.5-0.4
Condit. Reinf. active-inactive response ratio3.53.77.51.01.42.42.72.7-1.82.51.42.1-1.00.4
Condit. Reinf. active responses1.11.43.00.40.01.51.71.7-0.71.41.30.2-1.5-0.7
Condit. Reinf. inactive responses0.30.41.7-0.3-0.6-0.6-0.5-0.50.7-0.8-0.4-1.3-0.4-0.6
Incentive salience index mean1.01.32.51.10.71.41.61.6-0.81.51.10.9-0.9-0.3
Condit. Reinf. lever presses0.20.30.70.80.20.30.30.30.30.60.60.7-0.3-0.8
Condit. Reinf. active minus inactive responses0.30.51.00.71.0-0.5-0.3-0.30.5-0.8-0.70.70.70.9
Condit. Reinf. active-inactive response ratio0.20.31.1-0.10.4-0.3-0.0-0.00.3-0.5-0.21.01.00.6
Condit. Reinf. active responses0.60.92.81.71.6-0.5-0.5-0.50.1-0.8-0.90.40.61.4
Condit. Reinf. inactive responses0.71.06.22.51.60.40.10.1-0.40.2-0.30.1-0.61.2
Condit. Reinf. lever presses0.60.92.20.91.2-1.0-0.6-0.6-0.2-0.9-1.0-0.41.21.5
Condit. Reinf. lever reinforcers received0.60.92.11.31.4-0.7-0.6-0.60.0-0.9-1.10.10.81.4
Conditioned reinforcement - actives0.83.35.60.2-0.72.22.12.11.31.12.42.2-2.3-1.8
Conditioned reinforcement - inactives0.10.31.0-1.0-0.70.20.30.30.6-0.40.5-0.0-0.7-0.7
Conditioned locomotion0.81.16.5-0.1-1.4-0.5-0.6-0.62.6-0.91.10.3-0.6-0.8
Patch foraging indifference point 0 sec0.30.82.3-0.6-1.5-0.4-0.3-0.31.4-0.61.5-0.7-0.3-0.6
Patch foraging indifference point AUC0.20.52.51.61.2-0.20.00.00.2-0.0-0.10.40.51.2
Delay disc. indifference point, 0s delay0.81.05.4-0.0-1.2-0.6-0.7-0.72.3-0.60.80.2-0.4-1.0
Delay disc. indifference point, 16s delay0.20.31.11.0-0.10.40.40.40.20.50.90.2-0.60.2
Delay disc. indifference point, 2s delay0.80.93.8-0.8-1.2-0.8-0.8-0.82.0-0.5-0.2-0.6-0.5-1.1
Delay disc. indifference point, 24s delay0.50.81.3-0.9-1.1-1.1-1.1-1.10.7-1.0-0.4-1.00.2-0.6
Delay disc. indifference point, 4s delay0.60.61.9-0.8-0.7-0.8-1.0-1.00.0-0.8-0.3-1.40.60.3
Delay disc. indifference point, 8s delay0.30.62.30.3-0.11.00.90.9-0.40.90.4-0.1-1.5-0.1
Indifference point function ln k0.30.91.7-0.1-0.41.11.11.1-0.81.21.30.1-1.1-0.8
Indifference point function log k0.30.91.7-0.1-0.41.11.11.1-0.81.21.30.1-1.1-0.8
Patch foraging total patch changes 0 sec0.20.62.4-0.3-1.3-0.3-0.2-0.21.2-0.51.6-0.6-0.3-0.4
Patch foraging total patch changes 12 sec0.20.20.40.4-0.1-0.6-0.5-0.50.5-0.60.5-0.40.50.6
Patch foraging total patch changes 18 sec0.20.42.4-0.3-0.9-0.10.00.00.80.01.50.1-0.0-0.5
Patch foraging total patch changes 24 sec0.31.12.61.00.21.21.11.10.61.11.61.2-1.2-0.6
Patch foraging total patch changes 6 sec0.61.12.00.3-0.5-1.4-1.3-1.31.2-1.20.6-0.71.40.8
Patch foraging time to switch 0 sec0.20.95.2-2.3-1.3-0.3-0.5-0.50.6-0.6-0.2-0.0-0.0-1.1
Patch foraging water rate 0 sec0.10.52.51.60.9-0.1-0.0-0.0-0.70.30.10.10.71.0
Patch foraging water rate 12 sec0.41.73.21.61.51.51.51.5-1.51.80.21.2-0.50.4
Patch foraging water rate 18 sec0.20.41.31.00.9-0.1-0.2-0.2-0.70.10.20.41.10.9
Patch foraging water rate 24 sec0.60.81.81.20.50.81.01.0-0.91.11.30.6-0.00.3
Patch foraging water rate 6 sec2.23.210.41.32.01.91.91.9-3.22.20.50.7-0.11.5
Seeking ratio, delayed vs. immediate footshock2.23.25.8-2.1-1.6-2.1-2.2-2.20.9-2.1-1.4-2.41.0-0.5
Distance traveled before self-admin0.20.53.90.40.20.00.00.00.60.50.50.9-0.5-2.0
Distance traveled after self-admin0.20.31.2-0.3-0.30.30.30.30.50.51.10.3-0.4-1.1
Extensor digitorum longus weight2.811.132.94.75.72.72.52.5-3.82.8-2.13.8-0.72.4
Bone: elastic displacement0.50.72.41.51.20.50.70.7-0.60.9-0.51.0-0.00.2
Bone: elastic work1.01.43.81.52.00.30.60.6-1.50.9-1.01.20.91.4
Bone: endosteal estimation0.20.64.32.10.90.20.30.30.40.40.40.5-0.6-0.1
Bone: endosteal perimeter0.61.46.12.51.10.81.01.00.51.10.71.3-1.1-0.6
Epididymis fat weight0.42.17.82.81.71.21.21.2-0.21.81.21.4-1.0-0.0
Delta time in closed arm before/after self-admin1.41.32.80.40.41.71.61.6-0.60.91.31.1-1.4-0.3
Delta time in open arm before/after self-admin1.31.63.80.7-0.01.41.41.40.81.40.51.4-2.0-1.6
Diff in mean of infusions in LGA sessions0.91.74.5-2.1-1.0-1.2-1.3-1.3-0.2-1.60.1-1.31.80.9
Delay discount exponential model param0.20.20.80.60.70.40.40.4-0.30.30.10.90.2-0.1
Extinction: sum of active levers before priming0.71.12.7-0.80.4-1.0-1.0-1.0-1.2-1.0-1.3-0.91.61.1
Active lever presses in extinction session 60.80.82.2-1.3-1.5-0.6-0.6-0.61.1-0.91.2-0.80.40.0
Bone: final force0.20.30.91.00.80.20.50.5-0.30.40.40.70.30.5
Bone: final moment0.20.31.01.00.8-0.00.20.2-0.40.10.00.50.50.7
Food consumed during 24 hour testing period0.51.04.21.11.50.90.40.4-2.00.8-0.50.30.11.2
Glucose0.71.02.91.71.70.00.30.3-1.50.6-0.4-0.30.61.5
Heart weight1.01.66.82.62.10.50.70.7-0.60.7-0.71.3-0.21.4
Delay discount hyperbolic model param0.20.30.90.70.80.40.50.5-0.60.40.01.00.2-0.0
Intermittent access intake day 1-15 change0.10.51.1-0.8-0.8-0.7-0.7-0.70.9-0.70.3-0.30.0-1.0
Intermittent access intake escalation0.21.21.8-1.0-1.2-1.3-1.3-1.31.3-1.20.2-0.70.4-1.0
Intermittent access intake escalation 20.81.44.0-2.0-1.1-1.4-1.5-1.50.6-1.1-0.4-0.51.3-0.7
Intermitt. access day 1 inactive lever presses0.00.31.10.70.60.30.30.3-0.80.1-0.4-0.4-0.31.0
Intermitt. access day 15 inactive lever presses0.20.93.71.91.60.40.50.5-1.20.6-0.60.2-0.50.7
Intermitt. access escalation Index0.10.21.30.50.60.00.20.2-0.40.1-1.10.3-0.20.1
Intermittent access day 1 total infusions0.41.32.61.51.61.11.21.2-1.61.00.20.3-0.41.1
Intermittent access day 15 total infusions0.00.10.20.50.4-0.2-0.1-0.1-0.3-0.10.4-0.20.20.1
Intermittent access terminal intake (last 3 days)0.20.30.80.30.30.60.70.7-0.70.70.90.4-0.2-0.3
Intermittent access total infusions0.70.81.31.11.01.01.11.1-1.10.80.80.5-0.40.3
Intermittent access day 1 locomotion0.50.83.51.91.30.70.80.8-0.40.70.60.8-0.40.6
Intermittent access day 15 total locomotion0.20.62.20.5-0.4-0.8-0.7-0.71.5-0.11.00.2-0.0-1.3
Intermittent access total locomotion0.10.10.50.70.5-0.3-0.3-0.30.2-0.20.50.40.2-0.0
Intermittent access standard deviation0.00.10.30.40.2-0.00.10.10.3-0.10.40.50.3-0.0
Left kidney weight0.32.48.02.52.80.90.80.8-1.81.2-0.71.50.11.7
Right kidney weight0.42.67.52.72.61.01.21.2-1.71.4-0.61.7-0.11.5
Cocaine induced anxiety0.10.21.00.9-0.2-0.1-0.1-0.11.0-0.40.60.3-0.10.2
Post-drug Anxiety0.30.42.10.5-0.5-0.4-0.3-0.31.5-0.70.7-0.1-0.2-0.3
Baseline Anxiety0.10.10.5-0.60.30.10.30.3-0.7-0.1-0.4-0.10.20.2
Tail length0.10.52.00.61.40.40.10.1-0.5-0.0-0.91.00.21.0
Length with tail0.41.65.11.22.30.90.80.8-1.70.6-0.61.30.41.8
Length without tail0.10.71.60.90.90.90.80.8-0.50.80.71.3-0.10.8
Times rat made contact with spout1.51.73.7-1.4-0.2-0.9-1.3-1.3-1.3-1.4-1.0-1.41.91.5
Lifetime Intake0.91.11.81.30.91.31.31.3-1.01.01.00.6-0.70.2
Liver weight, left0.50.81.80.70.10.80.80.80.61.11.31.3-0.9-0.7
Liver weight, right0.30.52.1-0.0-0.20.40.40.40.80.51.41.50.0-0.6
Locomotor activity0.20.41.30.70.4-0.5-0.3-0.3-0.4-0.8-0.3-0.80.31.1
Locomotor testing distance0.30.62.21.10.9-0.2-0.1-0.1-1.0-0.5-0.7-0.90.11.5
Locomotor testing rearing0.62.27.5-0.10.9-0.9-0.9-0.9-2.0-1.2-0.9-2.21.82.7
Locomotion in novel chamber4.96.610.9-2.4-2.3-3.3-3.3-3.31.8-3.1-1.4-2.92.3-0.2
Locomotion in novel chamber post-restriction0.41.12.8-1.30.3-0.5-0.8-0.8-1.1-1.1-1.7-1.40.80.9
Fecal boli incidents, locomotor time 10.10.41.2-0.2-0.10.90.80.80.20.10.70.1-1.1-0.4
Change in fecal boli incidents, locomotor task0.50.51.50.70.6-0.6-0.5-0.5-1.20.3-0.5-1.20.70.5
Time >=10cm from walls, locomotor time 11.11.42.6-0.6-0.9-1.6-1.6-1.61.1-1.3-0.0-1.01.60.6
Bouts of movement, locomotor time 10.50.71.7-0.7-0.3-1.0-0.9-0.9-0.0-0.9-0.7-0.71.30.9
Total resting periods, locomotor time 10.20.20.7-0.3-0.1-0.5-0.4-0.4-0.1-0.5-0.4-0.50.80.8
Rest time, locomotor task time 10.10.20.5-0.30.50.30.40.40.1-0.2-0.70.4-0.40.4
Distance moved, locomotor task time 10.10.20.60.80.2-0.2-0.4-0.4-0.40.1-0.2-0.60.30.5
Vertical activity count, locomotor time 10.00.20.40.5-0.4-0.5-0.6-0.60.2-0.20.1-0.50.4-0.0
Time >=10cm from walls, locomotor time 20.72.15.51.91.11.51.61.6-0.72.40.11.3-1.4-1.1
Bouts of movement, locomotor time 20.20.82.4-0.7-1.1-1.1-1.0-1.01.5-0.7-0.5-0.60.2-0.7
Total resting periods, locomotor time 20.20.92.3-0.7-1.1-1.2-1.1-1.11.5-0.8-0.5-0.80.2-0.6
Rest time, locomotor task time 20.61.12.4-0.50.0-1.3-1.3-1.30.6-1.6-1.4-1.10.70.7
Distance moved, locomotor task time 20.50.71.90.3-0.41.00.90.9-0.01.40.70.8-0.8-1.0
Vertical activity count, locomotor time 20.10.21.0-0.0-0.50.30.20.20.00.70.20.5-0.2-1.0
Light reinforcement 10.52.19.93.11.81.31.11.1-1.21.11.00.8-1.00.9
Light reinforcement 20.10.31.10.90.8-0.2-0.2-0.2-0.5-0.1-0.50.10.11.0
Bone: marrow area0.20.53.81.90.80.10.20.20.40.30.40.4-0.5-0.1
Bone: maximum diameter0.51.06.52.51.5-0.2-0.4-0.40.4-0.1-0.20.70.20.9
Bone: maximum force0.30.62.21.50.80.40.40.40.00.40.71.40.20.5
Bone: maximum moment0.20.42.21.50.80.00.10.1-0.00.10.31.00.50.8
Mean time between licks in bursts0.00.21.4-0.2-0.60.10.20.20.60.11.20.2-0.0-0.2
Mean num. licks in bursts1.02.68.7-0.70.2-1.6-1.8-1.8-0.6-1.6-2.9-1.81.41.3
Cd content in liver0.10.10.4-0.10.20.30.20.20.3-0.00.50.70.50.3
Co content in liver4.55.39.22.91.82.63.03.0-1.13.01.82.0-2.2-0.4
Cu content in liver1.31.63.5-1.8-1.9-1.0-1.1-1.11.0-1.40.8-1.41.0-0.7
Fe content in liver0.40.53.6-0.0-0.6-0.3-0.4-0.41.9-0.10.00.2-0.5-0.9
K content in liver1.11.13.4-0.8-1.0-1.3-1.2-1.21.0-0.50.0-1.90.7-0.7
Mg content in liver0.40.41.4-0.8-0.9-0.4-0.3-0.30.4-0.00.8-1.20.3-0.8
Mn content in liver0.91.01.6-0.20.4-1.1-1.1-1.1-0.1-1.1-1.3-1.21.31.1
Na content in liver0.30.30.90.1-0.3-0.7-0.9-0.90.5-0.40.0-0.60.40.3
Rb content in liver0.91.02.6-0.5-0.51.00.80.80.80.81.60.8-1.2-1.6
Se content in liver0.10.10.3-0.3-0.0-0.3-0.4-0.40.50.1-0.6-0.6-0.1-0.3
Sr content in liver0.90.81.90.10.9-1.2-0.8-0.8-0.6-0.6-1.4-1.10.61.2
Zn content in liver13.916.229.5-4.9-5.4-4.7-4.1-4.14.3-4.01.3-4.43.3-1.5
Bone: minimum diameter1.52.910.53.22.81.21.41.4-1.31.5-0.21.8-0.51.1
Time in familiar zone, hab. session 10.40.51.40.1-0.30.80.50.50.30.30.91.2-0.8-1.0
Time in novel zone, hab. session 10.20.20.80.30.2-0.7-0.3-0.30.5-0.3-0.9-0.50.10.4
Total zone transitions, hab. session 12.83.98.61.30.62.92.52.5-1.32.41.71.5-2.6-0.8
Total locomotion distance, hab. session 10.50.81.70.3-0.21.30.90.9-0.30.91.31.0-1.1-0.6
Locomotion velocity, hab. session 10.30.40.90.3-0.01.00.60.6-0.70.71.00.6-0.6-0.2
Time in familiar zone, hab. session 21.71.93.80.31.1-1.6-1.4-1.4-0.5-1.5-2.0-0.61.81.7
Time in novel zone, hab. session 21.21.33.0-0.6-1.21.11.01.00.90.81.70.3-1.5-1.6
Total zone transitions, hab. session 21.92.55.21.30.52.31.91.9-1.01.81.91.1-1.9-0.5
Total locomotion distance, hab. session 20.20.30.70.60.40.60.50.5-0.80.20.50.2-0.20.6
Locomotion velocity, hab. session 20.10.20.40.40.20.60.40.4-0.60.10.60.1-0.30.4
Novel to familiar place preference ratio0.10.10.5-0.1-0.00.0-0.4-0.4-0.70.0-0.0-0.60.20.5
Novelty place preference0.20.20.80.10.1-0.2-0.5-0.5-0.8-0.1-0.2-0.90.30.7
Time in novel zone, NPP test0.30.30.90.20.2-0.2-0.5-0.5-0.9-0.2-0.4-1.00.40.8
Total zone transitions, NPP test1.42.14.21.51.02.01.71.7-1.51.71.41.0-1.3-0.0
Total locomotion distance, NPP test0.10.10.50.10.10.40.30.3-0.60.00.70.40.30.3
Locomotion velocity, NPP test0.10.20.70.00.20.30.20.2-0.9-0.10.60.20.60.7
Intraocular pressure0.10.21.00.1-0.1-0.10.10.11.0-0.2-0.40.6-0.4-0.5
Delta distance traveled before/after self-admin0.30.31.2-0.3-0.50.60.60.60.10.51.1-0.3-0.40.6
Delta ambulatory time before/after self-admin0.10.21.1-0.3-0.40.40.30.30.00.00.8-0.40.01.0
Parametrial fat weight0.10.31.0-0.3-0.5-0.6-0.3-0.31.00.10.70.40.2-1.0
Pavlov. Cond. lever latency0.60.82.60.41.20.60.80.8-1.60.8-0.90.30.11.1
Pavlov. Cond. magazine entry latency0.50.71.50.40.00.81.01.00.40.90.50.5-1.2-1.2
Pavlov. Cond. change in total contacts0.60.61.7-0.8-1.10.70.50.50.50.31.3-0.3-0.9-1.1
Pavlov. Cond. index score0.30.30.9-0.6-0.8-0.4-0.4-0.40.9-0.40.4-0.40.0-1.0
Pavlov. Cond. latency score0.40.51.4-0.7-1.1-0.5-0.6-0.61.2-0.60.5-0.50.0-1.0
Pavlov. Cond. lever contacts0.40.51.7-0.2-0.8-0.5-0.7-0.71.3-0.60.7-0.10.2-0.8
Pavlov. Cond. magazine entry number0.70.91.6-0.1-0.0-1.3-1.3-1.30.1-1.2-0.8-0.91.21.1
Pavlov. Cond. intertrial magazine entries0.20.21.10.2-0.4-0.2-0.1-0.11.0-0.30.70.5-0.1-0.1
Pavlov. Cond. lever-magazine prob. diff.0.30.40.8-0.8-0.9-0.6-0.6-0.60.6-0.60.2-0.80.2-0.8
Pavlov. Cond. response bias0.70.92.20.1-0.50.90.90.90.70.81.30.9-1.0-1.5
Pavlov. Cond. lever latency0.60.92.2-1.5-1.4-0.9-0.9-0.90.6-0.8-0.3-1.10.1-0.8
Pavlov. Cond. magazine entry latency0.00.10.2-0.5-0.2-0.20.30.30.3-0.20.2-0.0-0.20.1
Pavlov. Cond. change in total contacts0.00.10.40.60.3-0.10.10.10.2-0.10.40.20.30.6
Pavlov. Cond. index score0.10.10.20.40.4-0.3-0.1-0.10.4-0.4-0.10.50.30.5
Pavlov. Cond. latency score0.10.10.5-0.2-0.1-0.3-0.1-0.10.7-0.50.20.30.30.1
Pavlov. Cond. lever contacts0.60.92.71.61.60.70.80.8-0.60.70.01.30.01.0
Pavlov. Cond. magazine entry number0.00.10.20.1-0.00.2-0.2-0.2-0.50.3-0.1-0.3-0.1-0.3
Pavlov. Cond. intertrial magazine entries0.51.01.81.01.0-0.9-1.2-1.2-0.4-0.9-1.3-0.21.11.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.30.3-0.3-0.1-0.10.5-0.4-0.10.50.40.5
Pavlov. Cond. response bias0.91.33.61.91.80.91.01.0-0.70.9-0.11.3-0.31.0
Time in closed arm before self-admin0.10.20.8-0.5-0.90.10.20.20.20.60.80.20.1-0.1
Time in closed arm after self-admin0.40.41.8-1.0-1.3-0.2-0.2-0.20.2-0.21.2-0.40.50.2
Time in open arm before self-admin1.72.15.60.31.4-1.1-1.1-1.1-1.6-1.2-1.8-1.31.72.4
Time in open arm after self-admin0.30.40.80.70.70.60.60.6-0.00.4-0.60.6-0.9-0.3
Bone: periosteal estimation0.61.58.12.82.20.20.20.2-0.50.3-0.41.20.11.1
Bone: periosteal perimeter0.91.78.93.02.10.70.70.7-0.20.8-0.31.5-0.70.6
Bone: post-yield work0.71.33.70.2-1.50.20.20.21.90.41.90.8-1.0-1.7
Progressive ratio test 1 active lever presses1.62.75.21.61.72.02.32.3-2.11.70.60.6-1.30.7
Progressive ratio test 1 breakpoint1.52.54.81.51.52.02.22.2-2.01.60.70.5-1.20.7
Progressive ratio test 1 inactive lever presses0.20.62.00.50.9-0.00.10.1-1.4-0.3-0.8-1.1-0.01.0
Progressive ratio test 2 active lever presses0.91.32.60.61.51.31.51.5-1.61.00.01.1-0.50.4
Progressive ratio test 2 breakpoint0.81.02.70.51.41.01.21.2-1.60.8-0.10.8-0.20.6
Progressive ratio test 2 inactive lever presses0.20.61.20.30.61.01.11.1-0.50.40.40.9-0.9-0.3
Incentive Sensitization - Responses0.20.62.6-1.2-0.7-0.2-0.1-0.10.9-0.20.41.0-0.1-1.6
Incentive Sensitization - Breakpoint0.20.52.0-1.2-0.5-0.4-0.3-0.30.7-0.30.10.80.2-1.4
Sum of active levers in priming session hrs 5-63.83.66.9-2.4-1.0-2.3-2.3-2.3-0.2-2.0-1.4-1.82.60.7
Progressive ratio0.30.84.10.71.0-0.7-0.8-0.8-0.6-0.1-2.0-0.60.50.4
Food seeking constrained by brief footshock0.50.61.71.11.30.20.10.1-1.00.0-0.20.70.81.1
Seeking ratio, punishment vs. effort0.10.31.8-0.5-0.50.50.60.6-0.4-0.11.40.30.10.2
Retroperitoneal fat weight0.20.93.61.81.9-0.2-0.1-0.1-0.70.4-0.70.70.61.0
Reaction time number correct0.10.31.00.40.7-0.3-0.1-0.1-1.0-0.2-0.7-0.30.60.8
Reaction time mean minus median0.10.52.7-1.6-0.5-0.6-0.3-0.30.4-0.9-1.1-0.10.30.1
Reaction time mean minus median AUC0.10.83.9-2.0-0.7-0.8-0.6-0.60.4-1.1-1.1-0.50.60.2
Reaction time num false alarms0.91.56.01.20.01.61.21.20.51.20.90.6-2.4-1.1
Reaction time num false alarms AUC0.92.06.41.70.51.81.51.50.31.50.61.1-2.5-1.2
Reaction time trials correct on left0.10.31.00.40.7-0.3-0.1-0.1-1.0-0.2-0.7-0.30.60.8
Reaction time trials on left0.10.30.90.30.7-0.4-0.1-0.1-1.0-0.3-0.8-0.40.60.8
Reaction time mean0.61.24.8-0.80.4-0.9-0.8-0.8-0.7-1.2-2.2-1.00.91.5
Reaction time mean AUC0.51.25.1-0.70.6-0.7-0.6-0.6-0.9-1.0-2.2-1.00.81.5
Median of all reaction times0.91.35.0-0.20.9-0.7-0.7-0.7-1.2-1.0-2.2-1.00.91.8
Reaction time omissions0.81.22.9-1.7-1.2-1.2-0.8-0.81.2-1.5-1.4-0.80.4-0.3
Reaction time false alarm rate0.91.34.60.9-0.11.41.01.00.81.10.70.8-2.1-1.2
Reaction time premature initiation rate1.92.98.22.91.81.91.71.7-0.72.20.71.6-1.70.0
Reaction time premature initiations1.03.18.72.92.21.81.81.8-1.32.10.31.6-1.50.3
Std. dev. reaction times0.30.93.7-1.9-0.9-1.0-0.7-0.70.8-1.2-1.2-0.50.5-0.1
Reaction time trials completed0.10.30.90.30.7-0.4-0.1-0.1-1.0-0.3-0.8-0.40.60.8
Reaction time trials AUC0.10.30.80.50.8-0.30.00.0-0.9-0.2-0.6-0.20.50.8
Run reversals in cocaine runway, females0.50.62.2-0.9-0.2-0.8-0.4-0.4-0.9-0.5-0.5-1.50.80.8
Run reversals in cocaine runway, males0.80.94.0-1.00.30.10.10.1-2.00.1-1.0-1.20.61.3
Latency to leave start box in cocaine runway0.30.51.10.2-0.6-0.6-0.9-0.90.6-0.51.0-1.00.1-0.3
Latency to leave start box in cocaine runway, F0.50.62.90.5-0.50.40.10.11.00.31.70.4-0.8-0.8
Latency to leave start box in cocaine runway, M2.12.04.9-0.7-0.5-1.8-1.8-1.8-0.2-1.6-0.7-2.21.50.8
Std. dev. time between licks in bursts0.71.36.3-0.2-1.30.90.70.70.21.02.5-0.3-0.9-1.5
Total sessions with >9 infusions2.12.64.61.50.12.12.12.1-0.31.72.20.7-2.1-0.8
Short access day 1 total inactive lever presses0.20.41.40.5-0.00.80.90.9-0.50.71.20.1-0.5-0.3
Short access day 10 total inactive lever presses0.10.71.7-0.4-1.3-0.6-0.6-0.61.2-0.70.2-1.2-0.5-0.8
Short access day 1 total infusions1.53.06.71.0-0.62.02.02.00.41.72.61.2-2.2-1.8
Short access day 10 total infusions0.61.11.90.90.51.41.41.4-1.21.20.9-0.2-1.1-0.0
Short access total infusions1.11.63.01.20.41.71.71.7-1.11.31.40.0-1.5-0.0
Short access day 1 locomotion1.42.37.71.3-0.61.71.71.70.70.92.81.2-1.7-1.0
Short access day 10 total locomotion0.00.20.4-0.1-0.5-0.3-0.4-0.40.2-0.60.5-0.40.30.5
Short access total locomotion0.20.41.51.1-0.40.0-0.0-0.00.7-0.31.2-0.5-0.50.1
One hour access (0.3 mA shock)0.10.10.30.10.4-0.4-0.2-0.2-0.0-0.50.00.10.50.6
Compulsive drug intake0.61.02.40.30.5-1.6-1.2-1.2-0.1-0.7-1.4-0.61.20.8
One hour access (shock baseline)0.10.20.5-0.00.30.60.60.6-0.70.40.30.1-0.3-0.1
Social response proportion0.30.41.9-0.5-0.9-0.50.10.10.60.5-0.1-0.7-0.4-1.4
Social responses0.60.81.80.20.3-1.3-1.1-1.1-0.1-0.8-0.6-1.11.30.5
Social time0.91.42.3-1.4-1.3-1.5-1.4-1.41.5-1.0-0.3-0.80.9-0.9
Soleus weight0.72.17.02.72.21.21.21.2-1.11.5-0.31.3-1.10.3
Bone: stiffness0.30.62.41.51.10.30.30.3-0.60.30.30.80.31.2
Tibialis anterior weight3.411.739.64.86.32.21.71.7-4.52.2-3.22.90.13.5
Time to tail flick, vehicle, before self-admin0.30.41.0-0.8-0.80.20.10.10.9-0.10.6-0.1-0.8-1.0
Time to tail flick, vehicle, after self-admin0.40.84.01.0-0.3-0.2-0.2-0.22.00.00.10.8-0.8-1.7
Time to tail flick, test, before self-admin0.40.51.60.2-0.5-0.8-0.8-0.81.3-0.8-0.7-0.40.0-0.2
Time to tail flick, test, after self-admin0.10.10.50.0-0.30.10.10.10.70.40.50.5-0.2-0.3
Delta time to tail flick, vehicle, before/after SA0.60.63.71.90.50.20.30.30.70.60.50.7-0.7-0.7
Delta time to tail flick, test, before/after SA0.50.61.4-0.30.40.90.90.9-0.71.21.01.0-0.2-0.3
Tibia length0.61.66.01.32.40.1-0.1-0.1-1.0-0.1-1.70.90.72.1
Ambulatory time before self-admin0.20.54.20.00.00.00.10.10.40.50.50.6-0.5-2.1
Ambulatory time after self-admin0.61.03.1-0.6-0.90.50.50.51.30.51.70.6-1.0-1.8
Bone: tissue strength0.20.31.00.70.30.40.40.40.10.60.41.00.20.5
Total heroin consumption0.50.61.3-0.40.1-0.9-0.9-0.90.3-0.8-0.90.01.10.8
Bone: trabecular number0.20.51.8-0.4-0.9-0.5-0.7-0.71.4-0.8-0.20.2-0.1-0.3
Bone: trabecular spacing0.71.02.5-0.20.2-1.3-1.0-1.0-0.5-1.0-0.7-1.51.61.0
Bone: trabecular thickness0.10.20.7-0.40.50.60.20.2-0.80.4-0.40.4-0.40.1
Bone: trabecular tissue density0.20.41.3-0.60.30.80.60.6-1.10.7-0.5-0.2-0.40.3
Water consumed over 24 hours0.10.31.3-0.40.40.50.10.1-1.1-0.1-0.20.20.50.9
Number of responses in last shaping day3.14.07.31.80.82.52.52.5-0.42.41.61.6-2.7-1.7