Hub : Traits : Tibialis anterior weight : ← : →

chr2:92,382,532-96,055,722

Trait: Tibialis anterior weight

Best TWAS P = 2.60e-12 · Best GWAS P= 2.17e-12 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Tpd52	alternative polyA	NM_001401807.1	0.03	1	0.01	1.3e-02	-7	2.60e-12	0.03	TRUE
Adipose	Tpd52	alternative polyA	XM_063281536.1	0.03	1	0.01	1.1e-02	7	2.60e-12	0.03	FALSE
Adipose	Fabp4	alternative TSS	NM_053365.3	0.18	1	0.11	3.7e-12	-5.67	1.40e-08	0.38	FALSE
Adipose	Fabp4	alternative TSS	XM_063282611.1	0.17	1	0.11	6.5e-12	5.79	6.90e-09	0.55	FALSE
Adipose	Fabp9	alternative TSS	NM_022854.2	0.02	1927	0	1.1e-01	-5.62	1.88e-08	0.24	FALSE
Adipose	Snx16	alternative TSS	XM_006232135.5	0.12	1	0.06	1.8e-07	5.77	7.82e-09	0.51	FALSE
Adipose	Snx16	alternative TSS	NM_022289.3	0.06	1	0.02	1.4e-03	-5.77	7.82e-09	0.08	FALSE
Adipose	Snx16	alternative TSS	XM_006232135.5	0.06	1	0.02	1.4e-03	5.77	7.82e-09	0.08	FALSE
Adipose	Fabp12	gene expression	Fabp12	0.1	1	0.06	7.1e-07	-5.77	7.99e-09	0.47	FALSE
Adipose	LOC102553210	gene expression	LOC102553210	0.13	2179	0.09	3.3e-10	5.82	5.97e-09	0.58	FALSE
Adipose	LOC103691511	isoform ratio	XR_010064176.1	0.03	1	0.02	3.1e-03	-5.79	6.90e-09	0.03	FALSE
Adipose	Snx16	intron excision ratio	chr2_93262273_93263955	0.04	2093	0.02	2.1e-03	-5.52	3.48e-08	0.4	FALSE
Adipose	Fabp4	mRNA stability	Fabp4	0.08	1	0.04	1.0e-05	5.79	6.90e-09	0.44	FALSE
Adipose	LOC120093158	mRNA stability	LOC120093158	0.13	1	0.09	1.2e-09	5.77	7.82e-09	0.51	FALSE
BLA	Fabp4	gene expression	Fabp4	0.42	24	0.27	1.0e-14	5.53	3.20e-08	0.44	FALSE
BLA	Fabp5	gene expression	Fabp5	0.21	1	0.12	1.1e-06	5.62	1.95e-08	0.02	FALSE
BLA	Pag1	gene expression	Pag1	0.09	1	0.04	2.4e-03	-5.39	7.18e-08	0.04	FALSE
BLA	Pmp2	gene expression	Pmp2	0.09	1	0.03	8.4e-03	5.61	1.97e-08	0.04	FALSE
BLA	Impa1	mRNA stability	Impa1	0.07	1	0.02	4.0e-02	5.58	2.40e-08	0.04	FALSE
Brain	Zfp704	alternative TSS	XM_039103595.2	0.03	1	0.01	4.4e-02	-5.54	2.95e-08	0.03	FALSE
Brain	Zfp704	alternative TSS	XM_039103596.2	0.03	1	0.02	1.1e-02	5.54	2.95e-08	0.03	FALSE
Brain	Fabp4	gene expression	Fabp4	0.18	1	0.1	1.9e-09	5.63	1.80e-08	0.32	FALSE
Brain	Fabp5	gene expression	Fabp5	0.22	1	0.13	1.5e-12	6.44	1.17e-10	0.68	FALSE
Brain	LOC120093158	gene expression	LOC120093158	0.11	1	0.02	3.8e-03	-5.73	1.02e-08	0.04	FALSE
Brain	Pag1	gene expression	Pag1	0.05	1	0.03	6.6e-04	-5.67	1.40e-08	0.03	FALSE
Brain	Zbtb10	gene expression	Zbtb10	0.17	2399	0.09	7.2e-09	6.76	1.42e-11	0.63	FALSE
Brain	Snx16	isoform ratio	XM_006232135.5	0.06	2093	0.04	6.8e-05	-5.27	1.34e-07	0.38	FALSE
Brain	Tpd52	isoform ratio	XM_063281545.1	0.04	1	0.01	2.6e-02	-6.89	5.52e-12	0.03	FALSE
Brain	Snx16	intron excision ratio	chr2_93262273_93263955	0.13	2093	0.08	9.1e-08	-5.67	1.44e-08	0.56	FALSE
Brain	Tpd52	intron excision ratio	chr2_94712027_94720312	0.04	2151	0.01	3.4e-02	6.07	1.30e-09	0.26	TRUE
Brain	Tpd52	intron excision ratio	chr2_94713077_94719048	0.04	1	0.02	4.9e-03	-6.91	4.92e-12	0.04	FALSE
Brain	Mrps28	mRNA stability	Mrps28	0.08	2085	0.03	7.9e-04	6.42	1.32e-10	0.55	FALSE
Brain	Tpd52	mRNA stability	Tpd52	0.35	14	0.21	1.0e-19	-5.95	2.64e-09	0.57	FALSE
Brain	Zfp704	mRNA stability	Zfp704	0.05	1	0.04	1.9e-04	-6.64	3.08e-11	0.05	FALSE
Eye	Tpd52	intron excision ratio	chr2_94712027_94720312	0.35	35	0.06	5.0e-02	-6.73	1.72e-11	0.27	FALSE
IC	Fabp4	gene expression	Fabp4	0.1	1	0.05	3.2e-03	5.91	3.47e-09	0.05	FALSE
IC	Fabp5	gene expression	Fabp5	0.56	287	0.29	7.4e-13	5.47	4.45e-08	0.02	FALSE
IC	Hey1	gene expression	Hey1	0.12	1	0.09	1.6e-04	6.88	5.86e-12	0.06	FALSE
IC	LOC102553210	gene expression	LOC102553210	0.11	1	0.02	3.5e-02	-5.65	1.63e-08	0.04	FALSE
IC	Mrps28	gene expression	Mrps28	0.14	1	0.06	1.9e-03	6.87	6.44e-12	0.06	FALSE
IC	Zfp704	gene expression	Zfp704	0.11	2082	0.04	7.0e-03	-5.56	2.70e-08	0.22	FALSE
IL	Fabp4	gene expression	Fabp4	0.71	1955	0.06	1.3e-02	6.11	1.01e-09	0.58	FALSE
IL	Fabp5	gene expression	Fabp5	0.31	2131	0.1	1.8e-03	5.94	2.85e-09	0.18	FALSE
IL	Tpd52	mRNA stability	Tpd52	0.55	4	0.31	3.9e-08	-6.61	3.92e-11	0.59	FALSE
LHb	Stmn2	gene expression	Stmn2	0.34	46	0.09	4.7e-03	-6.83	8.58e-12	0.17	TRUE
LHb	Tpd52	gene expression	Tpd52	0.37	76	0.16	1.6e-04	-6.8	1.04e-11	0.56	FALSE
LHb	Impa1	mRNA stability	Impa1	0.48	1	0.1	2.2e-03	5.77	7.82e-09	0.06	FALSE
LHb	Tpd52	mRNA stability	Tpd52	0.47	9	0.21	9.8e-06	-6.37	1.84e-10	0.56	FALSE
Liver	Fabp5	gene expression	Fabp5	0.05	113	0.02	1.1e-03	6.02	1.79e-09	0.43	TRUE
Liver	Zbtb10	gene expression	Zbtb10	0.04	1	0.02	4.9e-03	5.42	5.99e-08	0.03	FALSE
Liver	Zfand1	gene expression	Zfand1	0.02	1	0.02	5.6e-03	-5.68	1.35e-08	0.03	FALSE
Liver	Chmp4c	mRNA stability	Chmp4c	0.04	2043	0.02	1.5e-03	-5.37	7.86e-08	0.37	FALSE
Liver	Tpd52	mRNA stability	Tpd52	0.12	1	0.06	4.4e-07	-6.68	2.38e-11	0.28	FALSE
NAcc	Fabp4	gene expression	Fabp4	0.15	48	0.17	4.2e-25	5.83	5.65e-09	0.63	FALSE
NAcc	Fabp5	gene expression	Fabp5	0.03	2131	0.02	2.2e-04	5.69	1.30e-08	0.36	FALSE
NAcc	Mrps28	gene expression	Mrps28	0.02	2085	0.01	3.9e-03	6.16	7.31e-10	0.29	FALSE
NAcc	Pag1	gene expression	Pag1	0.14	26	0.17	6.8e-25	-6.07	1.31e-09	0.02	FALSE
NAcc	Pmp2	gene expression	Pmp2	0.07	1	0.06	1.3e-09	5.42	5.99e-08	0.13	FALSE
NAcc	Stmn2	gene expression	Stmn2	0.02	1	0.02	1.1e-03	6.5	8.01e-11	0.03	FALSE
NAcc	Tpd52	gene expression	Tpd52	0.06	4	0.06	5.8e-09	6.6	4.09e-11	0.02	TRUE
NAcc	Zbtb10	gene expression	Zbtb10	0.13	40	0.11	1.1e-16	6.88	6.20e-12	0.66	FALSE
NAcc	Snx16	intron excision ratio	chr2_93262273_93263955	0.08	4	0.07	5.0e-11	-5.97	2.42e-09	0.6	FALSE
NAcc	Tpd52	mRNA stability	Tpd52	0.2	38	0.24	2.8e-35	-5.78	7.39e-09	0.3	FALSE
OFC	Fabp4	gene expression	Fabp4	0.41	1	0.14	4.3e-04	5.77	7.77e-09	0.06	FALSE
OFC	Fabp5	gene expression	Fabp5	0.39	2131	0.12	9.9e-04	6.22	5.11e-10	0.6	FALSE
OFC	Mrps28	gene expression	Mrps28	0.39	19	0.19	2.7e-05	6.5	8.23e-11	0.6	FALSE
OFC	Tpd52	gene expression	Tpd52	0.44	205	0.09	4.5e-03	-5.51	3.51e-08	0.32	FALSE
OFC	Zbtb10	gene expression	Zbtb10	0.27	1	0.08	5.8e-03	6.53	6.53e-11	0.05	FALSE
OFC	Tpd52	mRNA stability	Tpd52	0.36	350	0.12	8.3e-04	-5.83	5.40e-09	0.41	FALSE
PL	Fabp4	gene expression	Fabp4	0.44	105	0.34	8.0e-38	5.9	3.73e-09	0.66	FALSE
PL	Fabp5	gene expression	Fabp5	0.4	150	0.32	4.4e-36	6.14	8.09e-10	0.04	FALSE
PL	Hey1	gene expression	Hey1	0.16	1	0.05	5.9e-06	6.86	6.92e-12	0.51	FALSE
PL	Mrps28	gene expression	Mrps28	0.14	1	0.08	7.6e-09	6.64	3.08e-11	0.24	FALSE
PL	Pmp2	gene expression	Pmp2	0.09	23	0.06	7.6e-07	5.92	3.28e-09	0.58	FALSE
PL	Zbtb10	gene expression	Zbtb10	0.08	2399	0.04	7.7e-05	6.96	3.42e-12	0.64	FALSE
PL	Snx16	isoform ratio	XM_006232135.5	0.02	2093	0.01	1.6e-02	-5.77	7.70e-09	0.32	FALSE
PL	Snx16	intron excision ratio	chr2_93262273_93263955	0.11	1	0.07	2.8e-08	-5.89	3.83e-09	0.68	TRUE
PL	Tpd52	mRNA stability	Tpd52	0.35	19	0.24	3.7e-26	-5.52	3.39e-08	0.01	FALSE
pVTA	Fabp4	gene expression	Fabp4	0.1	57	0.11	3.0e-09	5.82	5.75e-09	0.5	FALSE
pVTA	Impa1	gene expression	Impa1	0.07	1	0.05	3.9e-05	5.76	8.24e-09	0.13	FALSE
pVTA	LOC108349981	gene expression	LOC108349981	0.11	3755	0.07	1.8e-06	5.73	9.82e-09	0.41	FALSE
pVTA	Pag1	gene expression	Pag1	0.14	1	0.07	2.2e-06	-5.4	6.85e-08	0	FALSE
pVTA	Snx16	isoform ratio	NM_022289.3	0.05	4	0.05	3.5e-05	5.24	1.64e-07	0.56	FALSE
pVTA	Snx16	isoform ratio	XM_006232135.5	0.08	9	0.07	3.0e-06	-6	1.92e-09	0.6	FALSE
pVTA	Tpd52	isoform ratio	XM_063281544.1	0.04	2151	0.03	2.7e-03	6.55	5.75e-11	0.46	FALSE
pVTA	Tpd52	isoform ratio	XM_063281545.1	0.05	7	0.03	1.1e-03	-6.69	2.31e-11	0.52	FALSE
pVTA	Pag1	intron excision ratio	chr2_93892679_93964594	0.09	26	0.04	4.7e-04	6.12	9.32e-10	0.21	FALSE
pVTA	Snx16	intron excision ratio	chr2_93262273_93263955	0.16	8	0.16	5.0e-13	-5.73	9.88e-09	0.6	FALSE
pVTA	Tpd52	intron excision ratio	chr2_94712027_94720312	0.07	2151	0.03	8.4e-04	5.9	3.60e-09	0.22	FALSE
pVTA	Mrps28	mRNA stability	Mrps28	0.05	1	0.04	7.2e-04	6.57	4.88e-11	0.04	FALSE
pVTA	Stmn2	mRNA stability	Stmn2	0.07	1	0.05	5.4e-05	6.72	1.85e-11	0.1	FALSE
pVTA	Tpd52	mRNA stability	Tpd52	0.12	2151	0.11	8.4e-09	-6.26	3.77e-10	0.6	FALSE
RMTg	Mrps28	mRNA stability	Mrps28	0.22	2085	0.09	2.7e-03	6.96	3.40e-12	0.48	FALSE