Best TWAS P=1.329237e-08 · Best GWAS P=1.133038e-05 conditioned to 0.001646567
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Brain | NA | gene expression | ENSRNOG00000067637 | 0.43 | 0.05 | enet | 40 | 0.12 | 8.6e-11 | -3.5 | -5.7 | 1.3e-08 | 0.23 | 0.32 | 0.63 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.