Hub : Genes

Prtg

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Prtg 0.1 0.06 5.7e-05 0.08 0.06 0.06 0.06 3.7e-05 2.8e-04 6.2e-04 4.5e-04
2 RMTg gene expression Prtg 0.2 0.11 2.1e-03 0.1 0.1 0.1 0.07 1.2e-03 1.3e-03 1.5e-03 6.3e-03
3 Adipose isoform ratio XM_039081519.2 0.02 0.01 6.5e-03 0.01 0.02 0.01 0.01 3.3e-02 6.0e-03 6.2e-02 3.0e-02
4 Adipose alternative TSS XM_039081519.2 0.04 0.02 5.9e-05 0 0.02 0.01 0.01 8.2e-02 5.7e-03 1.0e-02 6.2e-02
5 Adipose alternative TSS XM_039081517.2 0.03 0.02 7.0e-04 0.01 0.02 0.01 0.01 4.7e-02 3.4e-03 1.9e-02 2.0e-02
6 Adipose alternative TSS XM_039081519.2 0.05 0.03 3.2e-06 0.01 0.02 0.02 0.01 3.3e-02 1.4e-03 2.3e-03 6.9e-03
7 Liver alternative TSS XM_039081519.2 0.07 0.04 7.7e-07 0.03 0.04 0.04 0.04 8.3e-04 1.1e-05 1.5e-05 2.4e-05
8 Liver alternative TSS NM_001037651.2 0.07 0.04 1.6e-06 0.04 0.04 0.04 0.04 3.6e-05 1.1e-05 1.2e-05 2.2e-05
9 Liver alternative TSS XM_039081519.2 0.09 0.05 2.8e-08 0.05 0.06 0.04 0.05 5.1e-06 9.4e-07 3.3e-05 2.4e-06
10 Liver alternative TSS XM_039081517.2 0.09 0.05 4.4e-08 0.05 0.05 0.04 0.05 7.1e-06 1.2e-06 1.2e-05 3.3e-06
11 Liver gene expression Prtg 0.37 0.14 0.0e+00 0.23 0.25 0.25 0.25 8.9e-25 1.1e-27 2.4e-27 7.0e-28
12 Adipose gene expression Prtg 0.2 0.09 0.0e+00 0.16 0.13 0.15 0.16 1.0e-17 5.7e-14 2.4e-16 3.3e-17
13 Liver mRNA stability Prtg 0.05 0.04 4.6e-03 0.01 0 0 0.01 1.5e-02 7.3e-02 1.5e-01 4.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.10.20.30.40.4-0.4-0.30.3-0.3-0.50.6-0.50.50.30.0-0.4
Area under the delay curve0.40.61.8-0.2-0.20.60.7-0.80.8-0.50.7-0.70.71.41.0-0.9
BMI with tail5.519.235.2-5.0-5.05.95.9-5.75.93.8-3.23.3-3.1-0.43.81.2
BMI without tail1.05.38.9-2.3-2.33.03.0-2.73.02.5-2.22.3-2.2-0.71.31.4
Body weight3.213.827.6-4.1-4.25.25.3-5.25.22.5-1.92.0-1.90.04.30.3
Weight adjusted by age1.64.76.4-2.2-2.22.42.2-2.12.12.5-2.42.4-2.4-1.60.92.2
Bone surface0.10.20.4-0.5-0.50.30.3-0.30.30.5-0.40.5-0.5-0.60.10.4
Bone volume0.10.20.3-0.5-0.50.50.6-0.50.60.3-0.20.3-0.3-0.30.60.2
Breakpoint value in progressive ratio session0.00.00.10.00.00.30.4-0.30.40.2-0.10.2-0.10.10.10.0
Number of licking bursts0.82.55.11.91.9-2.1-2.12.2-2.1-0.90.6-0.70.6-0.2-2.20.2
Context. condit. distance diff. score0.40.41.50.20.20.00.1-0.20.1-0.80.8-0.90.90.80.7-1.2
Locomotion velocity, session 11.82.05.2-1.2-1.20.80.6-0.50.51.8-1.91.8-1.8-1.6-0.62.3
Locomotion distance, session 10.30.31.50.40.4-0.6-0.70.8-0.70.1-0.20.2-0.2-0.3-1.20.6
Locomotion velocity, session 20.10.10.60.20.20.10.2-0.10.20.4-0.30.4-0.4-0.0-0.20.8
Locomotion distance, session 20.20.31.00.10.10.20.30.00.20.8-0.70.9-0.8-0.2-0.71.0
Locomotion velocity, session 31.11.33.60.40.4-0.9-1.01.2-1.00.9-1.01.1-1.1-1.0-1.91.8
Locomotion distance, session 31.92.24.02.02.0-1.9-1.92.0-1.9-1.00.8-0.80.80.4-1.8-0.2
Stereotopy head waving bouts, day 30.60.71.6-1.2-1.20.80.6-0.70.60.8-0.90.8-0.8-0.60.40.8
Stereotopy head waving duration, day 31.21.43.0-1.7-1.71.21.0-1.11.01.2-1.21.1-1.2-0.80.71.1
Locomotion velocity, session 70.60.71.01.01.0-1.0-0.90.9-0.9-0.90.8-0.80.80.5-0.5-0.4
Locomotion distance, session 71.11.42.81.51.5-1.6-1.51.7-1.5-0.60.5-0.50.40.1-1.50.2
Stereotopy head waving bouts, day 70.91.01.7-0.9-0.90.80.7-0.60.71.3-1.31.3-1.3-1.1-0.21.3
Stereotopy head waving duration, day 71.11.43.0-0.9-0.90.60.4-0.30.41.5-1.61.6-1.6-1.7-0.51.7
Locomotion velocity, session 80.50.61.4-0.3-0.30.00.00.1-0.01.0-1.01.1-1.1-1.2-0.51.2
Locomotion distance, session 80.30.41.11.01.0-0.7-0.70.8-0.6-0.30.3-0.10.20.4-0.8-0.2
Degree of sensitization distance0.00.00.10.10.1-0.2-0.20.2-0.2-0.00.0-0.00.0-0.1-0.10.2
Degree of sensitization stereotypy0.80.81.4-0.7-0.70.70.6-0.50.61.2-1.21.2-1.2-1.1-0.31.2
Conditioned locomotion1.41.64.0-0.4-0.41.21.4-1.51.5-0.81.0-1.01.12.01.8-1.3
Cocaine response after cond. corrected2.74.17.3-2.7-2.72.22.0-2.12.02.1-2.01.9-1.9-1.61.31.4
Cocaine response after cond. not corrected2.02.95.6-2.4-2.41.91.7-1.81.71.7-1.61.5-1.5-1.31.21.1
Cocaine response before conditioning0.70.91.71.11.1-0.6-0.60.5-0.5-1.11.1-1.11.11.3-0.3-1.0
Saline control response0.40.51.6-0.2-0.3-0.3-0.50.5-0.50.7-0.90.8-0.9-1.0-0.91.3
Bone: connectivity density1.11.73.71.61.6-1.8-1.81.9-1.8-0.60.5-0.40.3-0.1-1.80.1
Bone: cortical apparent density0.60.91.51.11.1-1.2-1.21.1-1.2-0.90.7-0.90.80.5-0.90.1
Bone: cortical area0.61.02.8-1.6-1.61.11.1-1.41.1-0.10.1-0.30.20.21.70.2
Bone: cortical porosity0.80.81.70.70.7-0.7-0.50.4-0.5-1.31.3-1.31.31.20.4-0.9
Bone: cortical porosity1.51.63.30.90.9-0.7-0.50.4-0.5-1.71.8-1.71.81.60.7-1.6
Bone: cortical thickness0.40.61.9-0.0-0.0-0.4-0.30.0-0.3-1.31.2-1.41.30.80.7-0.5
Bone: cortical thickness0.20.20.6-0.2-0.2-0.3-0.30.0-0.2-0.70.6-0.80.70.50.60.0
Bone: cortical tissue density0.61.01.61.21.2-1.2-1.21.2-1.2-0.90.7-0.80.80.5-1.00.1
Condit. Reinf. active minus inactive responses1.21.33.91.31.3-0.3-0.00.20.0-1.21.4-1.21.32.00.1-1.8
Condit. Reinf. active-inactive response ratio1.51.64.30.50.5-0.10.1-0.20.1-1.61.7-1.71.72.10.9-2.1
Condit. Reinf. active responses0.30.31.31.21.2-0.3-0.20.5-0.1-0.20.4-0.10.20.5-0.7-0.6
Condit. Reinf. inactive responses1.21.63.60.80.8-0.6-0.61.1-0.61.3-1.31.6-1.5-1.9-1.91.6
Incentive salience index mean1.01.34.41.01.00.10.4-0.30.4-1.21.4-1.21.42.10.5-1.8
Condit. Reinf. lever presses0.60.92.60.90.90.30.5-0.40.5-0.91.2-1.01.11.60.7-1.4
Condit. Reinf. active minus inactive responses1.11.72.5-1.4-1.41.61.6-1.51.51.4-1.21.3-1.3-1.21.10.3
Condit. Reinf. active-inactive response ratio1.01.52.6-1.6-1.61.51.5-1.61.50.9-0.80.8-0.8-0.81.50.2
Condit. Reinf. active responses0.81.12.2-0.9-0.91.51.5-1.41.50.8-0.60.8-0.7-0.31.2-0.5
Condit. Reinf. inactive responses0.30.41.30.90.9-0.4-0.30.5-0.3-0.40.5-0.40.40.6-0.4-1.1
Condit. Reinf. lever presses0.30.51.20.20.2-0.2-0.2-0.0-0.2-1.00.9-1.01.00.50.7-1.1
Condit. Reinf. lever reinforcers received0.60.92.0-0.8-0.81.31.4-1.31.40.5-0.30.5-0.4-0.11.3-0.7
Conditioned reinforcement - actives0.00.00.1-0.3-0.30.10.0-0.10.00.2-0.20.2-0.2-0.30.20.4
Conditioned reinforcement - inactives0.00.10.4-0.4-0.5-0.0-0.1-0.0-0.10.3-0.40.3-0.3-0.50.00.6
Conditioned locomotion0.50.82.00.30.3-0.00.1-0.20.2-1.11.2-1.21.21.01.1-1.4
Patch foraging indifference point 0 sec0.10.30.9-0.4-0.30.20.2-0.10.10.7-0.80.7-0.8-0.5-0.41.0
Patch foraging indifference point AUC0.51.13.41.81.8-1.0-0.81.1-0.8-0.80.9-0.60.70.8-1.1-0.8
Delay disc. indifference point, 0s delay1.01.12.11.31.4-0.8-0.70.8-0.6-1.11.1-1.01.11.4-0.5-1.1
Delay disc. indifference point, 16s delay0.91.33.4-0.2-0.10.50.6-0.80.6-1.21.3-1.31.41.81.5-1.7
Delay disc. indifference point, 2s delay0.10.10.10.10.1-0.4-0.40.3-0.4-0.30.2-0.20.20.1-0.3-0.2
Delay disc. indifference point, 24s delay0.10.20.50.10.3-0.00.0-0.10.0-0.60.6-0.60.60.70.4-0.7
Delay disc. indifference point, 4s delay0.90.92.20.60.5-0.10.1-0.20.2-1.21.3-1.21.31.50.8-1.4
Delay disc. indifference point, 8s delay0.30.51.1-0.6-0.61.01.0-1.01.10.2-0.10.1-0.00.80.6-0.4
Indifference point function ln k0.62.04.4-2.1-2.11.51.3-1.51.21.2-1.31.0-1.1-1.01.20.9
Indifference point function log k0.62.04.4-2.1-2.11.51.3-1.51.21.2-1.31.0-1.1-1.01.20.9
Patch foraging total patch changes 0 sec0.20.41.2-0.6-0.60.40.3-0.20.20.9-0.90.8-0.9-0.6-0.41.1
Patch foraging total patch changes 12 sec0.40.51.11.00.9-0.9-0.81.0-0.8-0.30.3-0.20.2-0.2-1.1-0.1
Patch foraging total patch changes 18 sec0.00.10.30.30.2-0.2-0.20.3-0.2-0.0-0.0-0.00.00.2-0.60.5
Patch foraging total patch changes 24 sec0.20.92.90.60.6-0.7-0.81.0-0.80.6-0.70.7-0.7-1.0-1.71.3
Patch foraging total patch changes 6 sec0.20.31.50.80.7-0.3-0.30.6-0.30.4-0.40.6-0.5-0.3-1.20.5
Patch foraging time to switch 0 sec0.31.12.30.80.8-1.0-0.80.6-0.7-1.41.4-1.41.40.70.4-1.5
Patch foraging water rate 0 sec0.62.33.2-1.7-1.81.71.5-1.41.41.8-1.81.7-1.7-0.90.51.6
Patch foraging water rate 12 sec1.45.79.6-2.5-2.41.91.6-1.51.53.0-3.13.0-3.0-2.6-0.02.8
Patch foraging water rate 18 sec0.30.71.2-1.0-0.90.70.6-0.60.51.0-1.11.0-1.0-0.9-0.11.0
Patch foraging water rate 24 sec0.60.92.30.30.3-0.6-0.80.9-0.80.7-0.90.8-0.9-1.4-1.51.3
Patch foraging water rate 6 sec0.71.01.9-0.9-0.90.70.5-0.40.41.3-1.41.3-1.3-1.3-0.41.3
Seeking ratio, delayed vs. immediate footshock0.71.01.5-1.2-1.11.21.2-1.11.21.0-0.91.0-0.9-0.30.50.3
Distance traveled before self-admin0.00.00.20.10.1-0.1-0.10.1-0.10.0-0.00.0-0.0-0.1-0.20.5
Distance traveled after self-admin1.12.03.2-1.7-1.71.31.1-1.21.01.5-1.61.4-1.5-1.60.51.8
Extensor digitorum longus weight5.421.633.4-5.5-5.55.85.8-5.55.74.6-4.04.2-4.0-2.13.61.8
Bone: elastic displacement0.10.10.3-0.2-0.20.40.5-0.40.5-0.00.1-0.00.10.20.5-0.3
Bone: elastic work0.40.51.4-0.1-0.10.40.5-0.60.5-0.80.9-0.90.90.81.2-1.1
Bone: endosteal estimation1.43.55.6-2.4-2.42.32.2-2.22.11.9-1.71.7-1.6-0.71.31.0
Bone: endosteal perimeter2.25.39.1-2.9-2.93.03.0-3.03.01.8-1.51.6-1.5-0.12.40.2
Epididymis fat weight0.00.20.40.60.5-0.5-0.50.7-0.50.2-0.20.3-0.3-0.4-0.60.6
Delta time in closed arm before/after self-admin0.30.30.70.30.3-0.3-0.30.1-0.2-0.80.7-0.80.80.70.1-0.7
Delta time in open arm before/after self-admin0.70.81.70.40.4-1.2-1.21.3-1.30.2-0.30.4-0.4-1.3-1.20.7
Diff in mean of infusions in LGA sessions0.71.33.4-0.8-0.71.41.6-1.51.6-0.00.3-0.20.30.91.8-1.4
Delay discount exponential model param0.30.41.30.30.3-0.6-0.70.7-0.70.4-0.50.5-0.5-1.1-0.90.8
Extinction: sum of active levers before priming0.30.41.70.10.2-0.3-0.40.5-0.40.6-0.70.6-0.7-0.8-0.91.3
Active lever presses in extinction session 60.40.40.6-0.7-0.70.60.6-0.50.60.8-0.70.8-0.8-0.70.10.2
Bone: final force0.60.92.4-1.3-1.31.21.2-1.41.20.2-0.10.0-0.00.11.5-0.3
Bone: final moment0.60.92.7-1.2-1.21.11.1-1.41.1-0.10.2-0.30.30.41.6-0.4
Food consumed during 24 hour testing period0.61.22.1-1.5-1.50.90.6-0.70.51.3-1.51.2-1.3-1.1-0.21.4
Glucose0.61.02.2-0.6-0.60.40.2-0.10.11.3-1.41.3-1.3-1.1-0.91.5
Heart weight0.50.71.9-0.5-0.51.31.4-1.11.40.6-0.40.6-0.40.21.0-0.7
Delay discount hyperbolic model param0.40.51.70.10.1-0.5-0.60.6-0.60.6-0.70.7-0.8-1.3-0.90.9
Intermittent access intake day 1-15 change0.10.61.7-0.6-0.6-0.1-0.30.3-0.30.8-1.00.9-0.9-1.3-0.81.0
Intermittent access intake escalation0.10.51.6-0.8-0.90.20.1-0.10.10.9-0.90.9-0.9-1.3-0.30.8
Intermittent access intake escalation 20.40.71.6-1.2-1.20.90.8-0.90.80.7-0.70.6-0.6-0.50.50.6
Intermitt. access day 1 inactive lever presses0.00.30.70.20.2-0.5-0.60.3-0.6-0.80.7-0.80.80.50.0-0.7
Intermitt. access day 15 inactive lever presses0.10.41.0-0.9-1.00.70.7-0.80.70.5-0.50.4-0.4-0.50.80.1
Intermitt. access escalation Index0.20.61.9-0.1-0.00.81.0-0.91.0-0.10.3-0.20.31.41.1-0.4
Intermittent access day 1 total infusions0.41.12.10.90.9-1.5-1.51.3-1.5-1.00.8-1.00.90.2-0.9-0.0
Intermittent access day 15 total infusions0.20.51.10.40.4-1.1-1.10.9-1.0-0.60.5-0.50.5-0.2-0.6-0.1
Intermittent access terminal intake (last 3 days)0.10.30.50.10.1-0.6-0.60.4-0.5-0.70.6-0.70.70.2-0.0-0.5
Intermittent access total infusions0.40.51.30.30.3-1.0-1.10.9-1.1-0.40.2-0.30.2-0.4-0.80.5
Intermittent access day 1 locomotion1.01.83.31.31.3-1.8-1.81.6-1.8-1.31.1-1.21.10.2-0.9-0.6
Intermittent access day 15 total locomotion0.10.51.10.40.3-0.7-0.70.5-0.7-1.00.9-1.01.00.30.2-0.5
Intermittent access total locomotion0.10.10.3-0.1-0.1-0.3-0.40.2-0.4-0.1-0.0-0.1-0.0-0.5-0.00.3
Intermittent access standard deviation0.00.20.9-0.6-0.6-0.1-0.10.0-0.20.2-0.30.2-0.3-0.6-0.10.9
Left kidney weight0.97.512.6-3.5-3.53.12.8-2.92.72.9-2.82.6-2.6-1.91.71.9
Right kidney weight0.96.69.7-2.9-2.82.62.3-2.22.23.1-3.13.0-3.0-2.20.62.2
Cocaine induced anxiety0.30.73.10.40.40.20.4-0.40.4-0.91.0-1.01.01.80.7-1.0
Post-drug Anxiety1.71.93.01.71.7-1.7-1.71.7-1.6-1.11.0-1.01.01.0-1.5-0.4
Baseline Anxiety1.83.08.81.41.4-2.1-2.32.5-2.40.3-0.60.6-0.7-1.5-3.01.4
Tail length0.31.73.71.51.5-1.8-1.81.9-1.9-0.30.1-0.10.0-0.8-1.60.8
Length with tail0.00.20.6-0.3-0.40.30.3-0.30.20.4-0.40.4-0.4-0.80.60.6
Length without tail1.26.413.0-2.9-3.03.53.5-3.63.41.4-1.11.0-1.00.03.4-0.2
Times rat made contact with spout0.00.00.3-0.2-0.2-0.0-0.20.1-0.2-0.0-0.1-0.10.0-0.1-0.60.3
Lifetime Intake0.30.41.00.30.3-1.0-1.00.9-1.0-0.30.2-0.20.2-0.5-0.60.5
Liver weight, left2.44.15.9-2.1-2.12.32.1-1.92.02.4-2.32.3-2.3-1.50.41.7
Liver weight, right1.22.13.2-1.6-1.61.51.4-1.31.41.8-1.71.7-1.7-1.40.41.0
Locomotor activity3.65.79.1-3.0-3.03.02.9-3.02.92.1-1.81.8-1.8-0.92.31.2
Locomotor testing distance1.94.77.4-2.7-2.72.52.4-2.42.32.1-2.01.9-1.9-1.41.61.6
Locomotor testing rearing0.31.31.8-1.3-1.31.21.0-1.01.01.4-1.31.3-1.3-1.00.40.8
Locomotion in novel chamber0.20.20.4-0.4-0.4-0.0-0.1-0.1-0.1-0.60.5-0.70.60.60.5-0.6
Locomotion in novel chamber post-restriction0.20.51.80.60.8-0.3-0.20.2-0.2-0.90.9-0.90.90.70.2-1.4
Fecal boli incidents, locomotor time 10.30.82.90.80.9-0.4-0.20.2-0.1-1.01.1-1.01.11.70.1-0.9
Change in fecal boli incidents, locomotor task1.51.53.9-1.9-2.00.80.5-0.80.51.2-1.51.1-1.3-1.30.11.6
Time >=10cm from walls, locomotor time 10.50.61.4-0.6-0.61.11.1-1.11.10.1-0.00.00.00.61.2-0.6
Bouts of movement, locomotor time 10.10.20.8-0.00.00.50.6-0.50.60.1-0.00.1-0.00.90.20.3
Total resting periods, locomotor time 10.10.10.60.10.10.30.4-0.30.40.1-0.10.0-0.00.8-0.00.4
Rest time, locomotor task time 10.50.94.50.40.30.40.5-0.60.5-1.01.0-1.11.12.10.9-0.4
Distance moved, locomotor task time 10.20.41.20.40.4-0.8-0.81.0-0.80.3-0.30.4-0.4-1.1-0.80.2
Vertical activity count, locomotor time 10.00.20.50.70.7-0.4-0.40.5-0.4-0.30.3-0.20.2-0.1-0.1-0.6
Time >=10cm from walls, locomotor time 20.10.31.70.10.00.50.6-0.60.6-0.20.2-0.30.31.30.60.1
Bouts of movement, locomotor time 20.20.71.4-0.6-0.60.70.7-0.50.71.2-1.11.2-1.1-0.3-0.50.8
Total resting periods, locomotor time 20.20.81.8-0.6-0.60.80.7-0.50.71.3-1.31.3-1.3-0.5-0.61.1
Rest time, locomotor task time 20.20.31.00.30.3-0.3-0.30.1-0.3-0.70.6-0.70.71.0-0.2-0.2
Distance moved, locomotor task time 20.40.51.30.50.4-0.6-0.70.9-0.70.6-0.60.8-0.8-1.1-0.80.7
Vertical activity count, locomotor time 20.40.92.11.31.2-1.4-1.41.4-1.4-0.40.3-0.20.1-0.4-1.00.3
Light reinforcement 10.73.27.5-1.7-1.62.72.7-2.62.71.2-0.91.0-0.90.41.8-0.0
Light reinforcement 20.10.30.9-0.2-0.1-0.2-0.2-0.1-0.2-0.80.7-1.00.90.80.3-0.2
Bone: marrow area1.53.76.1-2.5-2.52.32.2-2.22.21.9-1.71.7-1.6-0.71.41.0
Bone: maximum diameter2.34.79.2-3.0-3.02.72.6-2.82.61.6-1.51.3-1.3-0.42.21.0
Bone: maximum force0.51.12.9-1.3-1.31.21.3-1.51.30.2-0.10.1-0.00.11.7-0.3
Bone: maximum moment0.51.03.2-1.3-1.31.11.2-1.41.3-0.10.2-0.20.20.41.8-0.4
Mean time between licks in bursts0.10.60.90.80.8-0.9-0.90.8-1.0-0.90.8-0.80.80.3-0.4-0.5
Mean num. licks in bursts0.92.44.5-2.1-2.12.02.0-2.12.01.0-0.80.7-0.70.11.80.2
Cd content in liver1.11.32.31.51.5-0.9-0.60.8-0.6-1.31.4-1.21.21.1-0.0-1.3
Co content in liver1.92.26.51.11.1-0.20.1-0.10.2-1.92.0-2.02.02.60.9-1.9
Cu content in liver0.20.30.9-0.1-0.10.50.6-0.60.6-0.40.5-0.40.50.50.9-0.7
Fe content in liver0.50.61.8-0.5-0.50.20.10.00.11.0-1.11.1-1.1-1.0-0.81.4
K content in liver0.60.61.1-0.8-0.80.80.8-0.80.80.8-0.70.8-0.8-1.10.70.3
Mg content in liver0.50.60.9-0.7-0.71.00.9-0.90.90.7-0.60.7-0.7-0.70.60.1
Mn content in liver0.80.82.8-1.1-1.11.01.0-1.31.0-0.30.3-0.50.50.31.7-0.5
Na content in liver2.93.34.6-1.9-1.92.12.0-1.82.02.2-2.02.0-2.0-1.10.61.4
Rb content in liver0.91.11.9-1.1-1.10.70.6-0.50.61.4-1.31.4-1.4-1.3-0.21.2
Se content in liver0.40.51.40.10.1-0.7-0.70.7-0.80.3-0.50.4-0.5-1.2-0.91.1
Sr content in liver0.70.61.11.11.1-0.8-0.70.8-0.7-0.70.8-0.70.70.7-0.5-0.4
Zn content in liver0.40.51.9-0.0-0.00.50.6-0.70.6-0.50.6-0.60.60.61.0-1.4
Bone: minimum diameter0.81.64.2-1.0-1.01.21.4-1.61.4-0.80.9-1.01.01.62.1-1.0
Time in familiar zone, hab. session 10.40.50.9-0.0-0.00.60.7-0.70.7-0.50.6-0.60.71.00.9-1.0
Time in novel zone, hab. session 10.20.30.70.20.2-0.8-0.80.8-0.80.0-0.20.1-0.2-0.4-0.70.5
Total zone transitions, hab. session 10.50.72.50.90.9-0.9-0.91.1-0.90.3-0.40.4-0.4-0.3-1.60.8
Total locomotion distance, hab. session 10.40.51.90.50.5-0.5-0.60.8-0.60.5-0.60.7-0.7-0.8-1.40.8
Locomotion velocity, hab. session 10.30.51.40.20.2-0.2-0.30.5-0.30.7-0.80.8-0.8-0.9-1.21.0
Time in familiar zone, hab. session 20.20.30.80.40.4-0.6-0.70.7-0.70.1-0.20.2-0.2-0.6-0.90.4
Time in novel zone, hab. session 20.30.30.8-0.7-0.70.60.7-0.80.7-0.10.1-0.20.20.60.9-0.2
Total zone transitions, hab. session 20.10.10.30.50.50.20.30.00.30.2-0.10.3-0.20.2-0.4-0.3
Total locomotion distance, hab. session 20.10.10.40.30.30.50.6-0.30.60.3-0.10.3-0.20.3-0.1-0.6
Locomotion velocity, hab. session 20.10.10.60.30.30.40.5-0.30.60.10.10.10.00.40.1-0.8
Novel to familiar place preference ratio0.81.02.1-1.0-1.01.31.4-1.41.40.4-0.20.3-0.30.61.5-0.5
Novelty place preference0.91.22.6-1.1-1.11.41.6-1.61.60.4-0.20.3-0.20.61.6-0.5
Time in novel zone, NPP test1.11.42.8-1.4-1.41.61.6-1.71.60.6-0.40.5-0.40.31.6-0.2
Total zone transitions, NPP test0.10.20.40.10.10.40.4-0.20.40.6-0.50.6-0.50.2-0.60.3
Total locomotion distance, NPP test0.30.51.2-0.0-0.00.30.20.10.21.0-1.01.1-1.0-0.6-0.90.7
Locomotion velocity, NPP test0.30.51.60.50.5-0.2-0.20.6-0.30.8-0.80.9-0.8-0.5-1.30.7
Intraocular pressure0.00.00.10.20.2-0.3-0.30.3-0.3-0.10.1-0.00.0-0.2-0.2-0.0
Delta distance traveled before/after self-admin2.42.64.6-2.1-2.21.51.2-1.41.21.7-1.81.6-1.7-1.90.81.3
Delta ambulatory time before/after self-admin1.11.94.1-2.0-2.01.31.1-1.31.01.3-1.41.2-1.2-1.71.01.0
Parametrial fat weight1.22.94.82.22.2-2.1-2.12.1-2.1-1.41.1-1.21.10.6-1.80.1
Pavlov. Cond. lever latency0.30.41.9-0.9-0.9-0.1-0.30.0-0.30.4-0.60.4-0.6-1.40.00.7
Pavlov. Cond. magazine entry latency4.96.315.72.32.3-0.6-0.10.20.0-2.93.3-3.03.23.91.1-4.0
Pavlov. Cond. change in total contacts1.71.85.41.21.20.00.3-0.20.4-1.41.7-1.51.62.30.7-2.3
Pavlov. Cond. index score2.83.68.82.32.3-0.8-0.50.7-0.4-2.12.4-2.12.23.00.1-2.6
Pavlov. Cond. latency score2.02.66.82.02.0-0.7-0.40.6-0.3-1.72.0-1.71.82.6-0.1-2.1
Pavlov. Cond. lever contacts0.91.14.31.21.2-0.00.2-0.10.3-1.01.3-1.11.22.10.3-1.4
Pavlov. Cond. magazine entry number4.55.813.3-2.4-2.40.80.4-0.40.32.9-3.22.9-3.0-3.6-0.93.6
Pavlov. Cond. intertrial magazine entries1.51.85.40.10.1-0.6-0.81.0-0.91.4-1.51.6-1.6-2.3-1.81.8
Pavlov. Cond. lever-magazine prob. diff.2.73.48.72.22.2-0.7-0.30.5-0.2-2.02.3-2.02.22.90.3-2.6
Pavlov. Cond. response bias3.64.511.71.91.9-0.20.2-0.10.3-2.42.7-2.52.63.41.2-3.4
Pavlov. Cond. lever latency0.60.91.8-0.8-0.80.20.1-0.10.11.1-1.21.2-1.2-1.3-0.51.3
Pavlov. Cond. magazine entry latency2.33.34.62.12.1-2.0-1.91.8-1.9-2.01.8-1.91.91.3-1.2-0.8
Pavlov. Cond. change in total contacts0.41.01.61.31.2-0.9-0.80.8-0.8-1.21.2-1.21.21.0-0.3-0.7
Pavlov. Cond. index score0.91.52.21.51.5-1.1-1.00.9-1.0-1.51.5-1.41.41.1-0.3-1.0
Pavlov. Cond. latency score0.61.01.51.11.1-0.9-0.80.7-0.8-1.21.2-1.21.21.0-0.3-0.7
Pavlov. Cond. lever contacts0.50.71.70.80.8-0.3-0.20.1-0.1-1.11.1-1.11.21.30.3-1.2
Pavlov. Cond. magazine entry number2.32.94.2-2.1-2.02.01.9-1.91.91.8-1.71.7-1.7-1.01.20.7
Pavlov. Cond. intertrial magazine entries0.51.22.4-1.1-1.10.60.4-0.30.41.5-1.51.5-1.5-1.5-0.31.0
Pavlov. Cond. lever-magazine prob. diff.1.11.82.71.61.6-1.3-1.11.1-1.1-1.61.5-1.51.51.2-0.4-1.0
Pavlov. Cond. response bias1.82.54.11.81.8-1.1-0.90.9-0.9-2.02.0-1.92.01.9-0.0-1.8
Time in closed arm before self-admin0.20.30.90.20.20.00.1-0.10.2-0.60.7-0.70.70.90.4-0.9
Time in closed arm after self-admin0.20.20.40.30.4-0.3-0.20.2-0.2-0.60.6-0.60.60.6-0.1-0.6
Time in open arm before self-admin0.70.91.8-0.9-1.01.31.3-1.31.30.6-0.60.5-0.5-0.21.20.3
Time in open arm after self-admin0.40.40.7-0.7-0.80.60.6-0.60.50.6-0.60.6-0.6-0.70.60.6
Bone: periosteal estimation1.43.36.7-2.6-2.62.22.2-2.32.21.4-1.21.1-1.1-0.41.81.0
Bone: periosteal perimeter1.73.46.8-2.6-2.62.32.2-2.42.21.4-1.31.2-1.2-0.31.90.7
Bone: post-yield work0.10.10.2-0.3-0.30.40.4-0.30.40.3-0.20.3-0.3-0.20.3-0.1
Progressive ratio test 1 active lever presses0.20.41.00.40.4-0.9-1.01.0-1.0-0.20.0-0.10.0-0.3-0.90.4
Progressive ratio test 1 breakpoint0.20.41.00.40.5-1.0-1.01.0-1.0-0.20.1-0.10.1-0.2-0.90.4
Progressive ratio test 1 inactive lever presses1.12.97.21.31.3-2.5-2.72.5-2.7-0.60.2-0.40.2-0.9-2.20.8
Progressive ratio test 2 active lever presses0.20.30.7-0.8-0.80.40.4-0.50.40.5-0.50.5-0.5-0.70.30.6
Progressive ratio test 2 breakpoint0.20.30.7-0.8-0.80.40.4-0.40.40.5-0.50.5-0.5-0.80.20.6
Progressive ratio test 2 inactive lever presses0.00.10.1-0.3-0.3-0.3-0.30.1-0.4-0.30.2-0.30.3-0.30.30.1
Incentive Sensitization - Responses0.51.32.7-1.4-1.41.51.6-1.61.60.5-0.40.4-0.3-0.11.4-0.3
Incentive Sensitization - Breakpoint0.51.22.4-1.3-1.31.41.5-1.61.50.5-0.30.3-0.3-0.11.3-0.3
Sum of active levers in priming session hrs 5-60.20.20.6-0.2-0.20.0-0.00.1-0.10.5-0.50.5-0.5-0.6-0.20.8
Progressive ratio0.61.85.01.00.9-0.20.1-0.10.2-1.61.8-1.71.82.00.8-2.2
Food seeking constrained by brief footshock0.81.02.9-0.4-0.40.0-0.20.3-0.21.3-1.41.4-1.4-1.1-1.31.7
Seeking ratio, punishment vs. effort2.45.310.0-2.0-1.91.20.9-0.70.83.0-3.13.1-3.1-2.9-0.73.2
Retroperitoneal fat weight0.31.54.01.41.2-1.4-1.61.7-1.6-0.0-0.20.1-0.2-0.3-2.01.4
Reaction time number correct0.41.42.1-1.3-1.31.10.9-0.90.91.5-1.41.5-1.4-1.20.40.8
Reaction time mean minus median0.10.71.51.01.0-1.0-1.01.1-1.1-0.20.0-0.10.00.0-1.20.8
Reaction time mean minus median AUC0.21.43.01.41.3-1.5-1.61.6-1.6-0.30.1-0.20.1-0.3-1.71.1
Reaction time num false alarms0.30.61.20.60.7-1.0-1.11.1-1.10.0-0.20.2-0.2-0.7-1.00.8
Reaction time num false alarms AUC0.40.82.30.10.2-0.7-0.80.9-0.90.7-0.80.8-0.9-1.3-1.21.5
Reaction time trials correct on left0.41.42.1-1.3-1.31.10.9-0.90.91.5-1.41.5-1.4-1.20.40.8
Reaction time trials on left0.41.42.2-1.3-1.31.00.9-0.80.91.5-1.41.5-1.5-1.30.30.9
Reaction time mean1.32.94.62.01.9-2.1-2.12.0-2.1-1.61.4-1.51.41.0-1.6-0.3
Reaction time mean AUC1.22.84.42.01.9-2.1-2.12.0-2.1-1.51.3-1.41.31.0-1.7-0.1
Median of all reaction times2.53.95.72.22.2-2.4-2.32.2-2.3-2.11.8-2.01.91.4-1.5-0.8
Reaction time omissions0.30.51.20.40.4-0.6-0.70.8-0.70.4-0.50.5-0.6-0.9-1.01.1
Reaction time false alarm rate0.60.91.90.91.0-1.3-1.41.3-1.4-0.30.2-0.20.1-0.3-1.20.8
Reaction time premature initiation rate0.40.71.4-0.7-0.70.60.5-0.40.51.1-1.11.2-1.1-1.1-0.20.4
Reaction time premature initiations0.51.62.8-1.3-1.31.11.0-0.91.01.6-1.61.7-1.6-1.40.10.7
Std. dev. reaction times0.61.93.51.71.7-1.9-1.91.8-1.9-0.90.7-0.80.70.4-1.60.4
Reaction time trials completed0.41.42.2-1.3-1.31.00.9-0.80.91.5-1.41.5-1.5-1.30.30.9
Reaction time trials AUC0.31.21.9-1.2-1.20.90.9-0.70.81.4-1.31.4-1.4-1.20.30.8
Run reversals in cocaine runway, females0.20.20.8-0.4-0.4-0.1-0.30.2-0.30.5-0.70.5-0.6-0.5-0.20.9
Run reversals in cocaine runway, males0.40.51.00.10.1-0.1-0.10.4-0.10.9-0.81.0-1.0-0.9-1.00.8
Latency to leave start box in cocaine runway0.81.11.6-1.0-0.91.21.2-1.11.21.2-1.11.2-1.1-0.50.51.0
Latency to leave start box in cocaine runway, F0.60.72.3-0.1-0.10.20.10.00.01.1-1.11.2-1.2-1.2-0.61.5
Latency to leave start box in cocaine runway, M3.53.36.4-2.1-2.12.52.5-2.52.51.3-1.11.1-1.00.41.80.3
Std. dev. time between licks in bursts0.10.21.00.10.10.30.4-0.30.4-0.20.3-0.20.3-0.10.6-1.0
Total sessions with >9 infusions1.01.32.70.50.5-1.5-1.61.6-1.60.2-0.40.4-0.5-1.6-1.51.0
Short access day 1 total inactive lever presses0.10.31.2-0.6-0.6-0.5-0.60.4-0.60.1-0.30.2-0.3-1.10.10.7
Short access day 10 total inactive lever presses0.00.30.80.50.5-0.8-0.90.7-0.9-0.40.2-0.30.2-0.3-0.50.3
Short access day 1 total infusions0.10.20.7-0.00.0-0.6-0.60.6-0.60.1-0.20.2-0.2-0.8-0.20.8
Short access day 10 total infusions0.91.53.01.21.2-1.7-1.71.6-1.7-1.10.9-1.00.90.2-1.0-0.1
Short access total infusions0.81.22.90.90.9-1.7-1.71.6-1.7-0.50.3-0.30.2-0.7-1.20.5
Short access day 1 locomotion0.00.00.1-0.0-0.0-0.00.0-0.00.0-0.20.2-0.20.20.00.3-0.3
Short access day 10 total locomotion0.10.30.80.00.1-0.7-0.90.7-0.90.0-0.20.0-0.2-0.7-0.50.9
Short access total locomotion0.30.41.20.50.5-1.0-1.10.9-1.1-0.50.3-0.40.3-0.3-0.40.3
One hour access (0.3 mA shock)0.70.81.7-1.3-1.31.11.2-1.31.10.3-0.30.1-0.2-0.01.20.3
Compulsive drug intake0.71.12.4-1.5-1.50.90.7-0.80.71.1-1.21.0-1.0-1.10.10.9
One hour access (shock baseline)0.10.30.60.30.4-0.1-0.0-0.0-0.0-0.70.7-0.70.70.70.6-0.3
Social response proportion0.91.14.2-1.0-1.01.11.2-1.41.3-0.30.5-0.50.50.72.0-0.9
Social responses0.10.10.2-0.4-0.40.40.4-0.40.40.2-0.10.2-0.10.10.5-0.2
Social time0.30.41.6-0.7-0.60.20.1-0.20.10.7-0.80.7-0.8-0.9-0.21.3
Soleus weight10.932.248.3-6.7-6.76.96.8-6.46.75.8-5.25.4-5.2-3.14.02.4
Bone: stiffness0.81.52.6-1.4-1.40.70.5-0.50.51.5-1.61.6-1.6-1.60.01.5
Tibialis anterior weight10.134.752.9-7.3-7.36.66.3-6.16.26.3-5.96.0-5.9-4.23.43.6
Time to tail flick, vehicle, before self-admin0.70.92.41.61.5-0.8-0.71.0-0.7-0.60.6-0.40.50.9-1.0-0.9
Time to tail flick, vehicle, after self-admin0.00.00.1-0.3-0.30.0-0.0-0.1-0.0-0.20.1-0.20.2-0.00.30.0
Time to tail flick, test, before self-admin2.42.76.21.51.5-0.6-0.40.3-0.3-2.02.2-2.12.12.30.8-2.5
Time to tail flick, test, after self-admin1.61.72.71.41.5-1.7-1.61.6-1.6-1.21.0-1.01.00.8-1.3-0.2
Delta time to tail flick, vehicle, before/after SA0.10.10.5-0.7-0.70.0-0.1-0.2-0.1-0.1-0.0-0.20.1-0.40.30.5
Delta time to tail flick, test, before/after SA0.40.52.5-0.8-0.7-0.0-0.20.1-0.30.6-0.80.6-0.7-0.7-0.51.6
Tibia length0.61.74.1-0.9-0.91.11.2-1.51.3-0.91.0-1.21.21.62.0-1.6
Ambulatory time before self-admin0.10.30.60.70.7-0.8-0.70.7-0.8-0.40.3-0.30.30.2-0.60.4
Ambulatory time after self-admin0.91.42.7-1.6-1.60.90.7-0.80.61.2-1.31.1-1.2-1.60.51.4
Bone: tissue strength0.60.60.90.70.7-0.9-0.90.7-0.9-0.90.8-0.90.90.6-0.4-0.7
Total heroin consumption0.70.81.7-0.6-0.60.70.7-0.50.71.2-1.11.3-1.2-1.2-0.10.8
Bone: trabecular number0.61.01.81.31.3-1.2-1.11.2-1.1-1.01.0-0.80.80.6-0.7-0.6
Bone: trabecular spacing0.00.00.2-0.0-0.00.20.2-0.10.10.1-0.10.0-0.00.20.00.4
Bone: trabecular thickness0.10.10.5-0.7-0.70.20.2-0.40.2-0.0-0.0-0.10.0-0.20.60.3
Bone: trabecular tissue density4.57.914.9-3.9-3.93.13.0-3.22.92.5-2.42.2-2.2-1.92.71.9
Water consumed over 24 hours0.10.20.40.20.2-0.2-0.20.1-0.2-0.60.5-0.70.60.6-0.2-0.5
Number of responses in last shaping day0.00.00.1-0.4-0.30.20.1-0.10.10.2-0.20.2-0.2-0.20.2-0.1