Hub : Genes

Dock7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL mRNA stability Dock7 0.14 0.14 8.2e-03 0.04 0.05 0.06 0.05 4.1e-02 2.2e-02 1.6e-02 3.0e-02
2 OFC gene expression Dock7 0.31 0.23 9.8e-05 0.1 0.12 0.12 0.11 2.1e-03 1.2e-03 7.0e-04 1.4e-03
3 NAcc mRNA stability Dock7 0.06 0.05 9.1e-07 0.06 0.06 0.06 0.06 3.8e-07 3.1e-07 2.0e-07 2.3e-07
4 BLA gene expression Dock7 0.26 0.14 1.6e-15 0.25 0.26 0.26 0.26 1.8e-13 4.8e-14 2.5e-14 3.4e-14
5 Adipose gene expression Dock7 0.34 0.14 0.0e+00 0.27 0.27 0.27 0.27 7.8e-30 7.8e-30 4.6e-30 7.5e-30
6 PL intron excision ratio chr5_113751397_113757479 0.03 0.03 1.1e-03 0.03 0.03 0.02 0.02 6.5e-04 8.9e-04 2.2e-03 1.1e-03
7 NAcc intron excision ratio chr5_113689726_113692835 0.03 0.04 5.6e-03 0.01 0.01 0.01 0.01 4.2e-02 7.5e-03 3.8e-02 5.6e-02
8 Brain mRNA stability Dock7 0.19 0.15 1.0e-14 0.16 0.16 0.15 0.16 2.6e-14 3.1e-14 4.8e-14 1.7e-14
9 PL gene expression Dock7 0.49 0.22 0.0e+00 0.39 0.41 0.4 0.4 4.9e-46 1.2e-47 2.1e-47 3.6e-47
10 Liver gene expression Dock7 0.09 0.06 1.2e-09 0.06 0.06 0.05 0.05 1.0e-06 6.5e-07 1.8e-06 1.1e-06
11 LHb mRNA stability Dock7 0.15 0.14 5.6e-03 0.03 0.09 0.06 0.05 5.4e-02 4.1e-03 1.3e-02 2.3e-02
12 Brain gene expression Dock7 0.7 0.13 0.0e+00 0.57 0.57 0.57 0.57 2.0e-63 1.6e-64 5.1e-64 3.0e-64
13 Liver mRNA stability Dock7 0.03 0.03 3.1e-03 0.01 0.01 0 0.01 7.1e-02 3.3e-02 2.1e-01 6.5e-02
14 NAcc isoform ratio NM_001415886.1 0.03 0.04 9.5e-04 0.02 0.02 0.02 0.02 1.1e-03 9.2e-04 2.0e-03 1.6e-03
15 NAcc intron excision ratio chr5_113617633_113619139 0.03 0.03 1.0e-03 0.02 0.02 0.02 0.02 1.9e-03 7.8e-04 1.8e-03 1.9e-03
16 NAcc intron excision ratio chr5_113610926_113619139 0.02 0.02 2.6e-03 0.02 0.02 0.01 0.02 4.6e-03 2.3e-03 5.7e-03 5.2e-03
17 PL intron excision ratio chr5_113757584_113782662 0.03 0.03 2.4e-03 0.02 0.02 0 0.02 2.6e-03 2.0e-03 8.3e-02 2.2e-03
18 pVTA gene expression Dock7 0.36 0.22 8.0e-14 0.32 0.31 0.32 0.31 3.0e-14 7.3e-14 2.7e-14 7.3e-14
19 BLA mRNA stability Dock7 0.12 0.09 6.0e-07 0.11 0.12 0.11 0.11 1.8e-06 8.4e-07 1.4e-06 1.6e-06
20 PL mRNA stability Dock7 0.16 0.15 2.4e-12 0.11 0.11 0.1 0.11 4.9e-12 4.1e-12 2.3e-11 4.5e-12
21 LHb gene expression Dock7 0.57 0.25 5.4e-11 0.36 0.34 0.35 0.36 1.5e-09 4.8e-09 3.1e-09 2.6e-09
22 NAcc gene expression Dock7 0.27 0.18 0.0e+00 0.22 0.21 0.21 0.21 1.8e-24 8.9e-24 2.2e-24 2.8e-24
23 IL gene expression Dock7 0.37 0.24 4.3e-06 0.19 0.18 0.16 0.18 2.9e-05 3.3e-05 1.2e-04 3.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.10.20.3-0.50.5-0.50.50.5-0.50.40.4-0.5-0.40.5-0.5-0.5-0.50.5-0.5-0.50.50.50.50.50.40.5
Area under the delay curve0.40.41.0-0.80.8-0.60.50.5-0.80.40.1-0.7-0.50.5-0.9-0.5-0.60.6-0.6-0.60.70.60.71.00.10.2
BMI with tail0.00.20.20.4-0.40.4-0.3-0.30.3-0.3-0.40.50.4-0.40.50.40.4-0.40.40.4-0.4-0.4-0.4-0.4-0.4-0.4
BMI without tail0.20.50.60.8-0.80.7-0.6-0.60.7-0.6-0.60.70.7-0.70.80.70.7-0.70.70.7-0.7-0.7-0.7-0.8-0.7-0.6
Body weight0.10.20.4-0.50.5-0.50.60.5-0.50.50.4-0.4-0.50.5-0.5-0.5-0.50.5-0.5-0.50.50.50.50.40.40.3
Weight adjusted by age2.32.63.31.8-1.81.7-1.6-1.51.5-1.6-1.71.51.6-1.61.51.61.6-1.61.61.6-1.6-1.6-1.6-1.7-1.6-1.6
Bone surface2.23.94.42.1-2.12.1-1.9-2.01.9-2.0-2.02.02.0-2.02.02.02.0-2.02.02.0-2.0-2.0-2.0-1.9-2.0-1.9
Bone volume0.61.01.21.1-1.11.1-1.0-1.01.0-1.0-1.01.01.0-1.01.01.01.0-1.01.01.0-1.1-1.0-1.0-1.0-1.0-0.9
Breakpoint value in progressive ratio session0.30.30.6-0.70.7-0.50.40.5-0.30.50.7-0.5-0.50.5-0.4-0.5-0.50.5-0.5-0.50.40.50.50.80.70.7
Number of licking bursts0.00.10.10.2-0.20.3-0.2-0.20.3-0.2-0.20.30.2-0.20.30.20.2-0.20.20.2-0.3-0.2-0.3-0.2-0.2-0.2
Context. condit. distance diff. score2.93.54.0-2.02.0-2.01.91.9-1.91.81.7-1.9-1.81.9-1.9-1.9-1.91.9-1.9-1.91.91.91.91.91.81.9
Locomotion velocity, session 10.10.10.10.3-0.30.3-0.4-0.30.3-0.3-0.30.30.3-0.30.30.30.3-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.2
Locomotion distance, session 10.60.80.9-1.01.0-1.00.90.9-0.90.90.9-0.9-0.90.9-0.9-0.9-0.90.9-0.9-0.90.90.90.90.90.90.9
Locomotion velocity, session 20.20.20.50.6-0.60.5-0.4-0.40.6-0.3-0.10.60.4-0.40.70.40.5-0.50.50.4-0.6-0.4-0.6-0.6-0.2-0.2
Locomotion distance, session 20.20.20.30.5-0.50.5-0.5-0.50.4-0.5-0.50.50.5-0.50.50.50.5-0.50.50.5-0.5-0.5-0.5-0.4-0.5-0.6
Locomotion velocity, session 30.00.00.0-0.00.0-0.00.10.1-0.00.10.10.0-0.10.10.0-0.1-0.00.1-0.1-0.10.00.10.00.00.10.1
Locomotion distance, session 30.00.00.0-0.00.00.0-0.1-0.0-0.0-0.1-0.2-0.00.1-0.1-0.10.10.0-0.00.00.00.0-0.00.00.0-0.1-0.2
Stereotopy head waving bouts, day 30.40.50.6-0.70.7-0.70.80.8-0.60.70.8-0.6-0.70.7-0.7-0.7-0.70.7-0.7-0.70.70.70.70.60.70.7
Stereotopy head waving duration, day 30.81.01.4-1.01.0-1.01.11.1-0.91.11.2-0.9-1.01.0-0.9-1.0-1.01.0-1.0-1.00.91.00.90.91.01.1
Locomotion velocity, session 70.50.50.8-0.70.7-0.70.80.8-0.60.80.9-0.5-0.70.7-0.5-0.7-0.60.7-0.7-0.70.60.70.60.60.90.9
Locomotion distance, session 70.40.40.5-0.70.7-0.70.70.7-0.60.70.7-0.6-0.70.7-0.6-0.7-0.70.7-0.7-0.70.60.70.60.60.70.7
Stereotopy head waving bouts, day 71.01.21.61.2-1.21.2-1.0-1.01.2-1.0-0.91.21.0-1.01.21.01.1-1.11.11.1-1.2-1.1-1.1-1.2-0.9-0.9
Stereotopy head waving duration, day 71.11.31.61.3-1.21.2-1.2-1.11.2-1.1-1.11.21.1-1.11.21.11.2-1.11.11.1-1.2-1.1-1.2-1.2-1.1-1.1
Locomotion velocity, session 80.40.50.6-0.80.8-0.80.70.7-0.80.70.6-0.8-0.70.7-0.8-0.7-0.70.7-0.7-0.70.80.70.70.80.70.7
Locomotion distance, session 80.91.31.5-1.21.2-1.21.11.1-1.11.11.1-1.1-1.11.1-1.1-1.1-1.11.1-1.1-1.11.11.11.11.11.11.2
Degree of sensitization distance0.00.00.10.2-0.20.2-0.1-0.10.3-0.10.10.30.1-0.10.30.10.2-0.20.20.1-0.3-0.1-0.2-0.3-0.00.1
Degree of sensitization stereotypy1.21.31.61.3-1.21.2-1.2-1.11.2-1.1-1.01.21.1-1.11.21.11.1-1.11.11.1-1.2-1.1-1.2-1.2-1.0-1.0
Conditioned locomotion0.00.00.1-0.20.2-0.20.20.2-0.20.20.3-0.1-0.20.2-0.0-0.2-0.10.2-0.2-0.20.10.20.10.20.30.3
Cocaine response after cond. corrected0.60.71.01.0-1.00.9-0.8-0.71.0-0.7-0.60.90.8-0.81.00.80.9-0.80.80.8-0.9-0.8-0.9-0.9-0.6-0.6
Cocaine response after cond. not corrected0.50.50.80.9-0.90.8-0.7-0.60.9-0.6-0.50.80.7-0.70.90.70.8-0.70.70.7-0.8-0.7-0.8-0.9-0.5-0.5
Cocaine response before conditioning0.00.00.0-0.00.0-0.00.10.0-0.00.00.0-0.0-0.00.0-0.0-0.0-0.00.0-0.0-0.0-0.00.00.00.00.00.0
Saline control response0.10.20.3-0.50.5-0.40.40.4-0.50.40.4-0.4-0.40.4-0.5-0.4-0.40.4-0.4-0.40.30.40.40.50.40.3
Bone: connectivity density1.93.03.41.8-1.81.8-1.7-1.81.6-1.8-1.81.71.7-1.71.61.71.7-1.71.71.7-1.7-1.7-1.7-1.7-1.8-1.7
Bone: cortical apparent density8.110.711.7-3.43.4-3.43.33.3-3.23.33.2-3.2-3.33.3-3.2-3.3-3.23.3-3.3-3.33.33.33.23.23.33.2
Bone: cortical area0.10.20.30.5-0.50.5-0.4-0.40.4-0.4-0.50.40.4-0.40.40.40.4-0.40.40.4-0.4-0.4-0.4-0.4-0.5-0.4
Bone: cortical porosity0.50.50.60.7-0.70.8-0.7-0.60.7-0.7-0.80.70.7-0.70.70.70.7-0.70.70.7-0.7-0.7-0.7-0.7-0.7-0.7
Bone: cortical porosity0.60.70.80.8-0.80.9-0.8-0.80.9-0.8-0.90.90.8-0.80.80.80.8-0.80.80.8-0.8-0.8-0.8-0.8-0.8-0.8
Bone: cortical thickness0.30.50.6-0.70.7-0.70.80.7-0.70.70.6-0.6-0.70.7-0.6-0.7-0.70.7-0.7-0.70.60.70.70.60.60.7
Bone: cortical thickness0.00.00.1-0.00.0-0.10.10.10.00.20.4-0.0-0.10.10.1-0.1-0.00.1-0.1-0.10.00.1-0.0-0.10.30.3
Bone: cortical tissue density8.010.511.5-3.43.4-3.43.33.3-3.23.23.2-3.2-3.23.2-3.2-3.2-3.23.2-3.2-3.23.23.23.23.13.23.2
Condit. Reinf. active minus inactive responses0.10.10.30.1-0.10.2-0.3-0.30.1-0.3-0.50.00.3-0.2-0.10.20.2-0.20.20.2-0.1-0.2-0.1-0.1-0.5-0.5
Condit. Reinf. active-inactive response ratio0.10.10.2-0.30.3-0.30.10.2-0.40.1-0.1-0.4-0.20.2-0.5-0.2-0.30.2-0.2-0.20.40.20.30.4-0.0-0.1
Condit. Reinf. active responses0.50.61.10.7-0.70.8-0.8-0.80.6-0.9-1.00.60.8-0.80.50.80.7-0.70.70.7-0.6-0.7-0.6-0.6-1.0-1.0
Condit. Reinf. inactive responses0.30.40.50.6-0.60.6-0.5-0.60.6-0.6-0.70.60.6-0.60.50.60.6-0.60.60.6-0.6-0.6-0.6-0.6-0.7-0.6
Incentive salience index mean0.10.10.40.2-0.20.3-0.3-0.30.1-0.4-0.60.10.3-0.30.00.30.2-0.30.30.3-0.1-0.3-0.2-0.1-0.6-0.5
Condit. Reinf. lever presses0.10.20.2-0.40.4-0.40.40.4-0.50.30.2-0.4-0.40.4-0.5-0.4-0.40.4-0.4-0.40.40.40.40.50.20.3
Condit. Reinf. active minus inactive responses1.31.61.8-1.31.3-1.31.21.2-1.31.21.1-1.3-1.21.2-1.3-1.2-1.31.2-1.2-1.21.31.21.31.31.11.1
Condit. Reinf. active-inactive response ratio0.50.50.6-0.80.8-0.70.70.7-0.70.70.7-0.8-0.70.7-0.8-0.7-0.70.7-0.7-0.70.70.70.70.70.70.7
Condit. Reinf. active responses0.91.21.7-1.21.2-1.21.01.0-1.30.90.8-1.2-1.01.0-1.3-1.0-1.11.1-1.1-1.11.21.11.21.20.80.8
Condit. Reinf. inactive responses1.51.82.5-1.51.5-1.51.31.2-1.51.21.0-1.5-1.31.3-1.6-1.3-1.41.3-1.3-1.31.41.31.41.51.11.1
Condit. Reinf. lever presses3.14.24.62.1-2.12.1-2.1-2.11.9-2.1-2.12.02.1-2.11.92.12.0-2.02.02.0-2.0-2.0-2.0-1.9-2.1-2.1
Condit. Reinf. lever reinforcers received0.30.40.7-0.70.7-0.70.60.5-0.80.50.4-0.8-0.60.6-0.9-0.6-0.70.6-0.6-0.60.70.60.70.80.40.4
Conditioned reinforcement - actives0.20.20.4-0.50.5-0.50.40.4-0.60.40.6-0.5-0.40.4-0.5-0.4-0.40.4-0.4-0.40.40.40.40.50.40.4
Conditioned reinforcement - inactives0.60.61.9-0.90.9-1.00.80.7-1.40.60.4-0.8-0.70.7-0.9-0.7-0.80.7-0.7-0.70.90.70.80.90.50.4
Conditioned locomotion0.20.20.5-0.50.5-0.50.40.3-0.60.40.7-0.4-0.40.4-0.4-0.4-0.40.4-0.4-0.40.20.40.40.60.50.4
Patch foraging indifference point 0 sec6.210.010.83.2-3.23.3-3.2-3.12.9-3.2-3.23.23.2-3.23.13.23.2-3.23.23.1-3.1-3.1-3.1-3.0-3.2-3.2
Patch foraging indifference point AUC0.91.01.41.1-1.11.2-0.9-0.91.2-1.0-1.01.11.0-1.01.01.01.0-1.01.01.0-0.9-1.0-1.0-1.0-1.1-1.0
Delay disc. indifference point, 0s delay2.62.93.2-1.71.7-1.81.81.7-1.71.71.7-1.6-1.71.7-1.6-1.7-1.71.7-1.7-1.71.81.71.71.71.81.6
Delay disc. indifference point, 16s delay0.90.91.80.7-0.70.9-1.1-1.00.7-1.1-1.40.81.0-1.00.61.00.9-0.90.90.9-0.8-0.9-0.8-0.6-1.3-1.3
Delay disc. indifference point, 2s delay0.20.20.4-0.50.5-0.50.40.5-0.50.30.1-0.5-0.40.4-0.7-0.4-0.50.4-0.4-0.40.60.40.60.60.20.2
Delay disc. indifference point, 24s delay0.10.10.3-0.50.5-0.30.20.3-0.30.20.0-0.4-0.20.3-0.5-0.3-0.30.3-0.3-0.30.40.30.40.5-0.00.1
Delay disc. indifference point, 4s delay2.83.04.9-2.12.1-1.81.61.6-2.01.51.3-1.7-1.61.6-2.0-1.6-1.71.7-1.7-1.71.81.71.82.21.21.3
Delay disc. indifference point, 8s delay1.71.82.7-1.61.6-1.41.31.3-1.51.21.0-1.3-1.21.3-1.5-1.3-1.31.3-1.3-1.31.41.31.41.60.91.0
Indifference point function ln k0.30.40.7-0.60.6-0.60.50.6-0.40.70.8-0.5-0.60.6-0.4-0.6-0.50.6-0.6-0.60.40.60.50.50.90.8
Indifference point function log k0.30.40.7-0.60.6-0.60.50.6-0.40.70.8-0.5-0.60.6-0.4-0.6-0.50.6-0.6-0.60.40.60.50.50.90.8
Patch foraging total patch changes 0 sec5.69.19.83.1-3.13.1-3.0-3.02.7-3.0-3.03.13.0-3.03.03.03.0-3.03.03.0-3.0-3.0-3.0-2.8-3.0-3.1
Patch foraging total patch changes 12 sec1.01.32.11.0-1.01.2-1.2-1.11.0-1.3-1.31.01.2-1.20.81.21.1-1.11.11.1-1.0-1.1-1.0-0.8-1.4-1.4
Patch foraging total patch changes 18 sec1.92.43.11.6-1.61.7-1.5-1.51.4-1.6-1.71.61.6-1.61.41.61.6-1.61.61.6-1.4-1.5-1.5-1.4-1.7-1.7
Patch foraging total patch changes 24 sec1.51.92.21.5-1.51.5-1.3-1.31.4-1.3-1.11.51.3-1.41.51.41.4-1.41.41.4-1.4-1.3-1.4-1.3-1.2-1.3
Patch foraging total patch changes 6 sec2.33.33.91.8-1.81.9-1.9-1.81.5-1.9-2.01.91.9-1.81.71.81.8-1.81.81.8-1.8-1.8-1.8-1.6-1.9-2.0
Patch foraging time to switch 0 sec1.62.53.4-1.71.7-1.71.41.5-1.91.41.3-1.8-1.51.5-1.8-1.5-1.61.6-1.6-1.51.71.51.61.61.41.4
Patch foraging water rate 0 sec1.82.83.31.8-1.81.8-1.5-1.61.8-1.6-1.61.81.6-1.61.81.61.7-1.71.71.6-1.7-1.6-1.7-1.7-1.7-1.7
Patch foraging water rate 12 sec3.55.36.12.3-2.32.5-2.3-2.42.3-2.3-2.22.42.3-2.32.42.32.3-2.32.32.3-2.4-2.3-2.3-2.0-2.2-2.3
Patch foraging water rate 18 sec0.20.30.40.5-0.50.6-0.5-0.60.6-0.5-0.60.50.5-0.50.50.50.5-0.50.50.5-0.6-0.5-0.5-0.4-0.6-0.6
Patch foraging water rate 24 sec0.00.00.10.1-0.10.2-0.1-0.10.3-0.1-0.20.20.1-0.10.20.10.2-0.20.20.1-0.2-0.1-0.2-0.1-0.2-0.3
Patch foraging water rate 6 sec0.10.20.50.6-0.60.5-0.2-0.30.6-0.3-0.20.60.3-0.40.70.40.5-0.40.40.4-0.5-0.4-0.5-0.6-0.2-0.3
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.10.10.2-0.00.00.3-0.1-0.2-0.00.1-0.1-0.10.10.0-0.10.10.10.1-0.1-0.00.2-0.2-0.2
Distance traveled before self-admin0.10.10.1-0.10.10.2-0.3-0.30.2-0.3-0.30.10.2-0.20.10.20.2-0.20.20.2-0.2-0.2-0.10.2-0.4-0.4
Distance traveled after self-admin0.91.01.80.7-0.71.1-1.1-1.10.9-1.2-1.30.91.1-1.10.81.11.0-1.01.01.0-1.0-1.0-0.9-0.4-1.3-1.3
Extensor digitorum longus weight0.62.52.8-1.71.7-1.71.61.6-1.61.51.4-1.6-1.51.6-1.6-1.6-1.61.6-1.6-1.61.51.61.61.61.51.5
Bone: elastic displacement0.91.01.1-1.11.1-1.01.01.0-0.91.01.0-1.1-1.01.0-1.0-1.0-1.01.0-1.0-1.01.01.01.01.01.01.0
Bone: elastic work1.41.72.1-1.41.4-1.41.31.3-1.21.31.3-1.3-1.31.3-1.3-1.3-1.31.3-1.3-1.31.21.31.31.41.31.3
Bone: endosteal estimation0.71.41.61.3-1.31.3-1.2-1.21.1-1.2-1.21.21.2-1.21.21.21.2-1.21.21.2-1.2-1.2-1.2-1.1-1.2-1.1
Bone: endosteal perimeter1.53.03.31.8-1.81.8-1.7-1.71.6-1.8-1.81.71.8-1.71.61.71.7-1.71.71.7-1.7-1.7-1.7-1.6-1.8-1.7
Epididymis fat weight2.25.25.7-2.42.3-2.42.42.3-2.22.32.3-2.3-2.32.3-2.2-2.3-2.32.3-2.3-2.32.32.32.32.12.22.1
Delta time in closed arm before/after self-admin0.10.10.30.4-0.40.4-0.3-0.30.6-0.3-0.40.30.3-0.30.30.30.3-0.30.30.3-0.3-0.3-0.3-0.5-0.3-0.3
Delta time in open arm before/after self-admin1.31.31.61.1-1.11.1-1.3-1.20.8-1.2-1.11.11.2-1.21.11.21.2-1.21.21.2-1.2-1.2-1.2-0.9-1.1-1.1
Diff in mean of infusions in LGA sessions0.20.20.6-0.50.5-0.50.40.4-0.40.50.8-0.5-0.50.5-0.3-0.5-0.40.5-0.5-0.50.30.50.40.50.50.5
Delay discount exponential model param0.40.41.00.9-0.90.6-0.5-0.50.8-0.4-0.10.70.5-0.50.90.50.6-0.60.60.6-0.7-0.5-0.7-1.0-0.1-0.2
Extinction: sum of active levers before priming0.20.20.4-0.60.6-0.50.30.4-0.50.40.5-0.4-0.40.4-0.4-0.4-0.40.4-0.4-0.40.30.40.40.60.60.6
Active lever presses in extinction session 60.00.00.2-0.30.3-0.30.10.1-0.40.10.2-0.1-0.10.1-0.2-0.1-0.10.1-0.1-0.10.00.10.10.40.30.3
Bone: final force0.40.60.8-0.80.8-0.80.90.9-0.70.80.8-0.7-0.80.8-0.7-0.8-0.80.8-0.8-0.80.70.80.80.80.70.8
Bone: final moment0.00.00.1-0.10.1-0.10.20.2-0.10.20.2-0.1-0.20.2-0.1-0.2-0.10.1-0.1-0.10.00.20.10.10.10.2
Food consumed during 24 hour testing period0.20.20.4-0.50.5-0.50.40.3-0.60.30.2-0.5-0.40.4-0.6-0.4-0.40.4-0.4-0.40.40.40.50.60.20.2
Glucose0.00.00.10.1-0.10.00.0-0.10.10.10.30.2-0.0-0.00.30.00.1-0.00.00.0-0.2-0.0-0.1-0.20.20.1
Heart weight3.34.65.1-2.22.1-2.32.22.2-2.12.22.2-2.2-2.22.2-2.1-2.2-2.12.1-2.1-2.12.22.12.11.92.22.2
Delay discount hyperbolic model param0.50.51.21.0-1.00.7-0.7-0.60.9-0.5-0.20.80.6-0.61.00.60.7-0.70.70.7-0.8-0.7-0.8-1.1-0.2-0.3
Intermittent access intake day 1-15 change0.80.81.2-0.90.9-0.90.90.9-0.81.01.1-0.8-0.90.9-0.7-0.9-0.80.9-0.9-0.90.80.90.80.70.90.9
Intermittent access intake escalation0.60.60.9-0.80.8-0.80.80.8-0.70.90.9-0.7-0.80.8-0.6-0.8-0.80.8-0.8-0.80.70.80.70.60.80.8
Intermittent access intake escalation 20.70.71.0-0.80.8-0.80.90.9-0.60.90.9-0.8-0.90.9-0.7-0.8-0.80.8-0.8-0.80.80.80.70.61.00.9
Intermitt. access day 1 inactive lever presses1.21.31.61.1-1.11.0-1.1-1.20.8-1.2-0.91.21.2-1.21.21.21.2-1.21.21.2-1.3-1.2-1.2-1.0-1.2-1.2
Intermitt. access day 15 inactive lever presses1.01.12.3-1.11.2-1.20.90.8-1.50.91.0-0.9-1.01.0-0.9-1.0-0.91.0-0.9-1.01.01.00.91.31.01.0
Intermitt. access escalation Index0.90.81.41.0-1.00.9-0.8-0.91.2-0.9-0.70.90.9-0.90.90.90.9-0.90.90.9-0.9-0.9-0.9-1.0-0.7-0.7
Intermittent access day 1 total infusions0.10.10.8-0.40.4-0.40.20.2-0.90.20.3-0.2-0.20.2-0.3-0.3-0.20.2-0.2-0.30.20.30.30.70.20.2
Intermittent access day 15 total infusions0.50.61.2-0.80.8-0.90.70.7-1.10.70.9-0.6-0.70.7-0.6-0.7-0.70.7-0.7-0.70.60.70.70.80.80.7
Intermittent access terminal intake (last 3 days)0.10.10.4-0.30.3-0.40.30.3-0.60.30.4-0.2-0.30.3-0.2-0.3-0.20.3-0.3-0.30.20.30.20.40.40.3
Intermittent access total infusions0.30.40.9-0.60.6-0.70.60.6-0.90.60.8-0.5-0.60.6-0.5-0.6-0.50.6-0.6-0.60.40.60.50.70.60.6
Intermittent access day 1 locomotion0.10.10.30.2-0.20.2-0.4-0.5-0.1-0.4-0.10.40.4-0.40.40.40.4-0.40.40.3-0.5-0.4-0.4-0.0-0.2-0.2
Intermittent access day 15 total locomotion0.00.00.10.1-0.10.0-0.2-0.3-0.2-0.2-0.00.20.2-0.20.30.20.2-0.20.20.2-0.4-0.2-0.2-0.0-0.1-0.1
Intermittent access total locomotion0.10.10.30.4-0.40.3-0.3-0.40.2-0.20.20.50.3-0.30.60.30.4-0.30.30.3-0.6-0.3-0.4-0.20.0-0.0
Intermittent access standard deviation1.41.52.1-1.21.2-1.21.31.3-1.01.31.5-1.1-1.31.2-1.1-1.2-1.21.2-1.2-1.21.21.21.11.01.31.2
Left kidney weight0.31.01.1-1.01.0-1.01.00.9-0.91.01.0-0.9-1.01.0-0.9-1.0-1.01.0-1.0-1.00.91.01.01.01.01.0
Right kidney weight0.20.60.7-0.80.8-0.70.80.7-0.50.80.8-0.8-0.80.8-0.7-0.8-0.80.8-0.8-0.80.70.80.70.70.80.8
Cocaine induced anxiety0.10.10.3-0.40.4-0.40.40.4-0.50.30.3-0.3-0.30.3-0.4-0.3-0.30.3-0.3-0.30.40.30.40.50.10.1
Post-drug Anxiety1.11.21.5-1.21.2-1.21.11.1-1.21.00.9-1.1-1.11.1-1.2-1.1-1.11.1-1.1-1.11.11.11.11.10.90.9
Baseline Anxiety0.50.50.7-0.70.7-0.70.70.7-0.60.80.7-0.7-0.70.7-0.6-0.7-0.70.7-0.7-0.70.70.70.70.50.80.8
Tail length0.41.21.3-1.11.1-1.11.11.2-0.91.11.1-1.1-1.11.1-1.1-1.1-1.11.1-1.1-1.11.11.11.11.01.01.1
Length with tail0.31.21.4-1.21.2-1.11.11.1-1.11.00.9-1.1-1.11.1-1.2-1.1-1.11.1-1.1-1.11.21.11.11.10.90.9
Length without tail0.00.10.1-0.30.3-0.30.30.2-0.40.20.1-0.3-0.20.3-0.4-0.2-0.30.3-0.3-0.30.30.30.30.30.1-0.0
Times rat made contact with spout0.00.00.00.1-0.10.0-0.1-0.1-0.0-0.1-0.10.10.1-0.10.10.10.1-0.10.10.1-0.1-0.1-0.1-0.0-0.0-0.0
Lifetime Intake0.10.10.5-0.40.4-0.40.20.2-0.70.30.4-0.2-0.30.3-0.2-0.3-0.20.3-0.3-0.30.20.30.30.50.30.2
Liver weight, left2.03.23.8-1.91.9-1.91.81.8-1.91.71.5-1.8-1.71.8-1.9-1.8-1.81.8-1.8-1.81.81.81.81.91.61.5
Liver weight, right6.410.712.2-3.53.5-3.43.33.3-3.23.33.2-3.2-3.33.3-3.2-3.3-3.23.3-3.3-3.33.13.23.23.33.23.1
Locomotor activity0.00.00.00.0-0.00.0-0.0-0.10.0-0.0-0.0-0.00.00.0-0.0-0.0-0.00.0-0.0-0.0-0.1-0.00.0-0.0-0.1-0.2
Locomotor testing distance1.62.63.01.7-1.71.7-1.6-1.61.5-1.6-1.71.61.6-1.61.61.61.6-1.61.61.6-1.7-1.6-1.6-1.5-1.7-1.7
Locomotor testing rearing0.00.00.1-0.10.1-0.00.0-0.0-0.10.0-0.0-0.0-0.00.0-0.1-0.1-0.00.1-0.1-0.1-0.00.00.10.2-0.0-0.0
Locomotion in novel chamber1.51.92.41.5-1.51.4-1.5-1.51.3-1.3-1.11.41.3-1.31.51.31.4-1.41.41.4-1.5-1.4-1.4-1.4-1.0-1.1
Locomotion in novel chamber post-restriction0.10.10.3-0.10.1-0.30.20.2-0.10.30.3-0.3-0.30.3-0.2-0.3-0.30.3-0.3-0.30.30.30.2-0.00.50.5
Fecal boli incidents, locomotor time 10.00.00.0-0.00.0-0.1-0.1-0.1-0.20.00.10.1-0.0-0.00.10.00.1-0.00.00.0-0.1-0.0-0.1-0.00.10.1
Change in fecal boli incidents, locomotor task0.10.10.2-0.30.3-0.30.40.3-0.20.30.4-0.4-0.30.4-0.5-0.4-0.40.4-0.4-0.40.50.40.40.30.20.2
Time >=10cm from walls, locomotor time 10.20.20.50.5-0.50.4-0.5-0.40.0-0.5-0.60.40.5-0.50.30.50.5-0.50.50.5-0.6-0.5-0.4-0.4-0.7-0.7
Bouts of movement, locomotor time 10.10.10.20.2-0.20.3-0.2-0.20.1-0.3-0.30.20.2-0.20.20.20.2-0.20.20.2-0.3-0.2-0.2-0.2-0.4-0.4
Total resting periods, locomotor time 10.10.10.30.3-0.30.4-0.3-0.20.2-0.3-0.40.30.3-0.30.20.30.3-0.30.30.3-0.4-0.3-0.3-0.2-0.5-0.5
Rest time, locomotor task time 10.10.10.10.2-0.20.3-0.3-0.40.3-0.3-0.30.30.3-0.30.30.30.3-0.30.30.3-0.3-0.3-0.3-0.0-0.3-0.3
Distance moved, locomotor task time 10.20.30.4-0.30.3-0.60.50.6-0.40.50.5-0.6-0.50.5-0.5-0.5-0.50.5-0.5-0.50.60.50.50.10.60.6
Vertical activity count, locomotor time 10.10.10.30.5-0.50.3-0.2-0.20.4-0.20.00.40.2-0.30.50.20.3-0.30.30.3-0.4-0.3-0.3-0.5-0.0-0.0
Time >=10cm from walls, locomotor time 22.52.73.7-1.61.6-1.81.61.7-1.91.61.6-1.7-1.61.6-1.7-1.6-1.61.6-1.6-1.61.61.61.61.51.51.5
Bouts of movement, locomotor time 20.60.71.30.9-0.91.0-0.6-0.50.8-0.8-0.90.70.8-0.80.60.80.7-0.70.70.8-0.7-0.7-0.7-0.8-1.1-1.1
Total resting periods, locomotor time 20.70.71.40.9-0.91.0-0.7-0.60.9-0.9-1.00.80.8-0.80.60.80.8-0.80.80.8-0.8-0.8-0.7-0.8-1.2-1.2
Rest time, locomotor task time 20.91.11.30.9-0.91.1-1.0-1.21.2-1.0-1.01.21.0-1.01.11.01.1-1.01.01.0-1.0-1.0-1.1-0.8-0.9-0.9
Distance moved, locomotor task time 21.92.23.1-1.31.3-1.61.51.6-1.41.61.7-1.5-1.51.5-1.3-1.5-1.41.5-1.5-1.41.41.51.41.01.81.8
Vertical activity count, locomotor time 20.50.61.2-0.60.6-0.80.70.8-0.60.91.1-0.7-0.80.8-0.5-0.8-0.70.7-0.7-0.70.50.70.60.41.01.0
Light reinforcement 10.40.81.2-1.11.1-0.90.80.9-0.90.80.5-1.0-0.80.8-1.1-0.8-0.90.9-0.9-0.91.10.91.01.10.60.6
Light reinforcement 20.30.50.6-0.80.8-0.70.80.8-0.50.70.6-0.6-0.70.7-0.7-0.7-0.70.7-0.7-0.70.80.70.70.60.70.7
Bone: marrow area0.61.31.51.2-1.21.2-1.1-1.11.1-1.1-1.11.11.1-1.11.11.11.1-1.11.11.1-1.1-1.1-1.1-1.1-1.1-1.0
Bone: maximum diameter0.61.11.51.1-1.11.1-1.0-1.00.9-1.1-1.21.01.1-1.00.91.01.0-1.01.01.0-0.9-1.0-1.0-1.0-1.2-1.1
Bone: maximum force0.10.20.3-0.40.4-0.40.50.5-0.40.40.4-0.3-0.40.4-0.4-0.4-0.40.4-0.4-0.40.30.40.40.40.40.4
Bone: maximum moment0.10.10.20.3-0.30.3-0.2-0.20.3-0.3-0.30.40.3-0.30.40.30.3-0.30.30.3-0.4-0.3-0.3-0.2-0.3-0.2
Mean time between licks in bursts6.49.010.4-3.23.2-3.23.02.9-3.12.92.9-3.0-2.93.0-3.1-3.0-3.03.0-3.0-3.03.03.03.03.02.82.8
Mean num. licks in bursts0.00.00.0-0.00.0-0.10.0-0.0-0.2-0.0-0.0-0.0-0.00.0-0.1-0.0-0.00.0-0.0-0.00.10.00.10.0-0.0-0.0
Cd content in liver1.21.41.51.2-1.21.2-1.2-1.21.2-1.1-1.11.21.1-1.21.21.21.2-1.21.21.2-1.2-1.2-1.2-1.2-1.1-1.1
Co content in liver0.10.20.3-0.40.4-0.40.50.4-0.40.40.4-0.3-0.40.4-0.3-0.4-0.40.4-0.4-0.40.40.40.40.40.40.5
Cu content in liver0.30.40.5-0.70.7-0.70.70.7-0.70.60.6-0.6-0.60.6-0.7-0.6-0.60.6-0.6-0.60.70.60.60.70.60.6
Fe content in liver0.70.91.01.0-1.01.0-0.9-0.90.9-0.9-1.00.90.9-0.90.90.90.9-0.90.90.9-0.9-0.9-0.9-0.9-1.0-1.0
K content in liver0.90.91.1-1.01.0-1.01.01.0-0.91.01.1-0.9-0.90.9-0.8-0.9-0.90.9-0.9-0.90.90.90.90.91.01.0
Mg content in liver0.50.60.70.8-0.80.8-0.7-0.70.8-0.7-0.50.80.7-0.70.80.70.8-0.70.70.7-0.8-0.7-0.8-0.8-0.6-0.6
Mn content in liver0.10.10.1-0.30.3-0.30.20.2-0.20.30.4-0.2-0.30.2-0.2-0.2-0.20.2-0.2-0.20.20.20.20.20.40.3
Na content in liver3.23.43.9-2.02.0-2.01.81.8-1.81.81.8-1.9-1.81.8-1.9-1.8-1.81.8-1.8-1.81.81.81.81.81.81.7
Rb content in liver0.60.70.9-0.90.9-0.90.90.9-0.80.90.9-0.8-0.90.8-0.7-0.9-0.80.8-0.8-0.80.80.80.80.80.90.9
Se content in liver1.11.31.41.2-1.21.2-1.2-1.21.1-1.2-1.11.11.2-1.21.11.21.1-1.11.11.1-1.1-1.1-1.1-1.1-1.1-1.2
Sr content in liver0.10.10.10.3-0.30.3-0.2-0.30.2-0.3-0.30.30.2-0.20.30.20.3-0.30.30.2-0.2-0.2-0.2-0.2-0.2-0.2
Zn content in liver0.80.91.11.0-1.01.0-1.0-1.01.0-0.9-0.81.00.9-0.91.00.91.0-0.90.90.9-1.0-0.9-1.0-1.0-0.8-0.7
Bone: minimum diameter1.63.13.41.8-1.81.8-1.7-1.71.7-1.8-1.81.81.7-1.71.71.71.7-1.71.71.7-1.7-1.7-1.7-1.7-1.8-1.7
Time in familiar zone, hab. session 12.92.73.1-1.81.8-1.71.61.7-1.61.61.6-1.6-1.61.6-1.6-1.6-1.61.6-1.6-1.61.61.61.61.61.61.7
Time in novel zone, hab. session 17.47.28.32.9-2.92.8-2.7-2.72.7-2.6-2.62.72.6-2.72.72.72.7-2.72.72.7-2.7-2.7-2.7-2.7-2.6-2.6
Total zone transitions, hab. session 11.52.12.5-1.61.6-1.51.41.4-1.51.31.2-1.5-1.41.4-1.6-1.4-1.51.4-1.4-1.41.51.41.51.51.21.3
Total locomotion distance, hab. session 10.00.10.1-0.30.3-0.30.20.3-0.20.30.3-0.2-0.20.2-0.2-0.2-0.20.2-0.2-0.20.20.20.20.20.20.3
Locomotion velocity, hab. session 10.10.10.2-0.40.4-0.40.30.4-0.30.30.4-0.3-0.30.3-0.3-0.3-0.30.3-0.3-0.30.30.30.30.30.30.3
Time in familiar zone, hab. session 20.60.60.7-0.80.8-0.80.80.8-0.80.80.8-0.8-0.80.8-0.8-0.8-0.80.8-0.8-0.80.80.80.80.80.80.8
Time in novel zone, hab. session 21.11.11.31.1-1.11.1-1.1-1.01.1-1.0-1.01.11.0-1.01.11.01.1-1.11.11.1-1.1-1.1-1.1-1.1-1.0-1.0
Total zone transitions, hab. session 24.66.06.6-2.52.5-2.62.52.5-2.42.52.5-2.3-2.52.4-2.3-2.4-2.42.4-2.4-2.42.42.42.42.42.52.5
Total locomotion distance, hab. session 22.02.63.6-1.61.6-1.71.71.7-1.51.71.9-1.4-1.71.6-1.3-1.6-1.51.6-1.6-1.61.51.61.51.51.81.8
Locomotion velocity, hab. session 21.62.23.0-1.51.5-1.51.51.5-1.31.61.7-1.3-1.51.5-1.2-1.5-1.41.5-1.5-1.51.31.51.41.31.61.6
Novel to familiar place preference ratio1.01.11.21.1-1.11.1-1.1-1.11.1-1.0-0.91.01.0-1.01.11.01.0-1.01.01.0-1.1-1.0-1.1-1.1-0.9-1.0
Novelty place preference0.70.70.90.9-0.90.9-0.9-0.90.9-0.7-0.60.80.8-0.80.90.80.8-0.80.80.8-0.9-0.8-0.9-0.9-0.7-0.7
Time in novel zone, NPP test1.01.01.41.1-1.11.1-1.0-1.01.1-0.9-0.71.11.0-1.01.21.01.0-1.01.01.0-1.1-1.0-1.1-1.1-0.8-0.8
Total zone transitions, NPP test1.72.42.7-1.61.6-1.61.61.6-1.51.61.6-1.5-1.61.6-1.5-1.6-1.51.5-1.5-1.61.51.61.51.51.61.6
Total locomotion distance, NPP test0.20.20.5-0.40.4-0.40.60.5-0.30.60.7-0.2-0.50.5-0.2-0.5-0.40.4-0.4-0.50.30.50.40.30.60.7
Locomotion velocity, NPP test0.30.40.6-0.60.6-0.60.70.7-0.50.70.8-0.5-0.70.6-0.5-0.6-0.60.6-0.6-0.60.50.60.60.50.70.7
Intraocular pressure0.00.00.10.0-0.00.1-0.1-0.1-0.1-0.1-0.20.00.1-0.1-0.10.10.0-0.10.10.10.0-0.1-0.00.0-0.2-0.2
Delta distance traveled before/after self-admin1.21.31.81.1-1.11.2-1.1-1.21.0-1.2-1.41.11.2-1.21.01.21.1-1.11.11.1-1.1-1.1-1.1-0.9-1.3-1.3
Delta ambulatory time before/after self-admin0.80.91.50.9-0.91.0-0.9-1.00.7-1.1-1.20.91.0-1.00.81.00.9-0.90.90.9-0.9-0.9-0.8-0.6-1.2-1.2
Parametrial fat weight4.79.211.23.3-3.33.2-3.0-3.03.1-2.9-2.83.13.0-3.03.23.03.0-3.03.03.0-3.0-3.0-3.1-3.2-2.7-2.6
Pavlov. Cond. lever latency0.30.40.7-0.60.6-0.70.60.6-0.50.70.9-0.5-0.70.6-0.5-0.6-0.60.6-0.6-0.60.50.60.50.50.90.7
Pavlov. Cond. magazine entry latency0.60.71.1-1.01.0-0.90.80.8-1.00.80.6-1.0-0.80.8-1.0-0.8-0.90.8-0.8-0.80.90.80.91.00.70.7
Pavlov. Cond. change in total contacts0.30.40.60.6-0.60.6-0.6-0.60.5-0.6-0.80.60.6-0.60.50.60.6-0.60.60.6-0.6-0.6-0.6-0.5-0.6-0.7
Pavlov. Cond. index score0.00.00.0-0.10.1-0.10.00.0-0.1-0.0-0.2-0.10.00.0-0.2-0.0-0.10.0-0.0-0.00.10.00.10.1-0.1-0.1
Pavlov. Cond. latency score0.00.00.10.0-0.00.0-0.1-0.1-0.0-0.1-0.3-0.00.1-0.1-0.10.10.0-0.00.00.10.0-0.1-0.00.0-0.2-0.1
Pavlov. Cond. lever contacts0.00.00.10.0-0.00.1-0.1-0.1-0.0-0.2-0.4-0.00.1-0.1-0.10.10.0-0.10.10.10.0-0.1-0.00.0-0.4-0.2
Pavlov. Cond. magazine entry number0.81.01.21.1-1.11.1-0.9-0.91.1-0.9-0.81.10.9-1.01.11.01.0-1.01.01.0-1.0-1.0-1.0-1.1-0.9-0.9
Pavlov. Cond. intertrial magazine entries0.60.70.8-0.90.9-0.90.80.8-0.90.80.8-0.9-0.80.8-0.9-0.8-0.90.8-0.8-0.80.90.80.90.90.70.7
Pavlov. Cond. lever-magazine prob. diff.0.00.00.0-0.10.1-0.10.00.0-0.1-0.0-0.2-0.20.00.0-0.2-0.0-0.10.0-0.0-0.00.10.00.10.1-0.1-0.0
Pavlov. Cond. response bias0.20.30.6-0.60.6-0.60.50.5-0.70.40.2-0.7-0.50.5-0.8-0.5-0.60.5-0.5-0.50.60.50.60.70.30.4
Pavlov. Cond. lever latency1.01.41.6-1.31.3-1.21.21.2-1.11.21.2-1.2-1.21.2-1.2-1.2-1.21.2-1.2-1.21.21.21.21.21.21.2
Pavlov. Cond. magazine entry latency1.51.72.11.3-1.31.3-1.4-1.41.1-1.4-1.41.21.3-1.31.11.31.3-1.31.31.3-1.2-1.3-1.2-1.2-1.4-1.4
Pavlov. Cond. change in total contacts2.12.83.11.8-1.81.7-1.7-1.81.6-1.7-1.71.61.7-1.71.61.71.7-1.71.71.7-1.6-1.7-1.6-1.6-1.7-1.6
Pavlov. Cond. index score1.62.02.31.5-1.51.5-1.5-1.51.3-1.5-1.51.31.5-1.41.31.41.4-1.41.41.4-1.3-1.4-1.4-1.3-1.5-1.5
Pavlov. Cond. latency score1.21.61.81.3-1.31.3-1.3-1.31.1-1.3-1.31.21.3-1.31.21.31.2-1.21.21.2-1.2-1.2-1.2-1.2-1.3-1.3
Pavlov. Cond. lever contacts2.12.93.21.8-1.81.8-1.8-1.81.5-1.8-1.81.61.7-1.71.61.71.7-1.71.71.7-1.6-1.7-1.6-1.6-1.7-1.7
Pavlov. Cond. magazine entry number0.40.50.7-0.60.6-0.70.80.8-0.50.80.9-0.5-0.70.7-0.5-0.7-0.60.7-0.7-0.70.60.70.60.50.80.8
Pavlov. Cond. intertrial magazine entries1.31.82.0-1.31.3-1.41.41.4-1.21.41.4-1.2-1.31.3-1.2-1.3-1.31.3-1.3-1.31.31.31.31.31.41.4
Pavlov. Cond. lever-magazine prob. diff.1.51.92.21.4-1.41.4-1.5-1.51.2-1.5-1.51.31.4-1.41.31.41.4-1.41.41.4-1.3-1.4-1.3-1.3-1.4-1.4
Pavlov. Cond. response bias1.72.32.61.6-1.61.5-1.6-1.61.3-1.6-1.61.41.5-1.51.41.51.5-1.51.51.5-1.4-1.5-1.4-1.4-1.6-1.6
Time in closed arm before self-admin0.00.10.1-0.20.3-0.20.30.2-0.30.20.1-0.2-0.20.2-0.3-0.2-0.20.2-0.2-0.20.20.20.30.40.10.1
Time in closed arm after self-admin0.00.00.10.0-0.10.10.20.10.30.1-0.0-0.0-0.10.1-0.1-0.1-0.10.1-0.1-0.10.10.10.1-0.1-0.0-0.1
Time in open arm before self-admin0.20.20.40.4-0.40.5-0.4-0.40.6-0.3-0.20.50.4-0.40.60.40.4-0.40.40.4-0.5-0.4-0.5-0.5-0.4-0.3
Time in open arm after self-admin2.83.13.71.6-1.61.8-1.9-1.91.5-1.8-1.71.81.8-1.81.81.81.8-1.81.81.8-1.8-1.8-1.8-1.4-1.8-1.7
Bone: periosteal estimation0.71.41.61.3-1.31.2-1.1-1.11.1-1.2-1.21.21.2-1.21.21.21.2-1.21.21.2-1.2-1.2-1.2-1.1-1.2-1.1
Bone: periosteal perimeter0.61.01.41.0-1.01.0-1.0-1.00.9-1.0-1.21.01.0-1.00.91.01.0-1.01.01.0-0.9-1.0-1.0-0.9-1.1-1.1
Bone: post-yield work1.62.22.61.6-1.61.6-1.4-1.51.5-1.4-1.41.51.5-1.51.61.51.5-1.51.51.5-1.5-1.5-1.5-1.5-1.4-1.3
Progressive ratio test 1 active lever presses4.44.66.5-2.42.4-2.42.12.1-2.62.02.1-2.1-2.12.1-2.2-2.1-2.12.1-2.1-2.12.12.12.12.41.91.8
Progressive ratio test 1 breakpoint5.45.67.9-2.62.6-2.62.32.3-2.82.32.3-2.3-2.32.3-2.4-2.3-2.32.3-2.3-2.32.22.32.32.72.12.1
Progressive ratio test 1 inactive lever presses1.92.14.8-1.71.8-1.61.31.3-2.21.21.3-1.3-1.31.3-1.5-1.3-1.31.3-1.3-1.41.21.41.41.91.01.0
Progressive ratio test 2 active lever presses0.20.20.5-0.40.4-0.50.30.3-0.70.40.5-0.3-0.40.4-0.3-0.4-0.30.4-0.3-0.40.40.30.30.50.50.4
Progressive ratio test 2 breakpoint0.20.20.5-0.50.5-0.60.40.4-0.70.50.6-0.4-0.40.4-0.3-0.4-0.40.4-0.4-0.40.40.40.40.50.50.5
Progressive ratio test 2 inactive lever presses0.10.10.8-0.40.4-0.40.10.1-0.90.10.2-0.2-0.10.2-0.3-0.2-0.20.2-0.2-0.20.20.20.20.60.0-0.0
Incentive Sensitization - Responses0.30.30.50.7-0.70.5-0.6-0.60.4-0.4-0.40.50.5-0.50.70.50.5-0.50.50.5-0.5-0.5-0.6-0.7-0.3-0.3
Incentive Sensitization - Breakpoint0.40.40.70.8-0.80.6-0.7-0.70.6-0.5-0.50.60.6-0.60.80.60.7-0.60.60.6-0.6-0.6-0.7-0.9-0.4-0.4
Sum of active levers in priming session hrs 5-61.71.62.0-1.41.4-1.41.21.3-1.41.21.3-1.2-1.21.2-1.2-1.2-1.21.2-1.2-1.21.21.21.21.41.31.4
Progressive ratio0.20.20.4-0.40.4-0.50.60.5-0.40.60.6-0.5-0.50.5-0.4-0.5-0.50.5-0.5-0.50.50.50.40.30.60.6
Food seeking constrained by brief footshock4.86.06.8-2.32.3-2.62.62.6-2.32.52.6-2.4-2.52.5-2.3-2.5-2.42.5-2.5-2.42.52.52.42.02.52.5
Seeking ratio, punishment vs. effort1.01.21.4-1.11.1-1.21.21.2-1.11.11.1-1.1-1.11.1-1.1-1.1-1.11.1-1.1-1.11.11.11.11.01.01.0
Retroperitoneal fat weight0.30.81.0-0.90.9-0.91.00.9-0.81.01.0-1.0-0.90.9-0.9-0.9-1.00.9-0.9-0.91.00.90.90.70.80.8
Reaction time number correct0.10.10.20.3-0.30.3-0.2-0.20.2-0.2-0.20.40.2-0.20.40.20.3-0.30.30.2-0.5-0.2-0.3-0.2-0.3-0.4
Reaction time mean minus median0.50.61.00.7-0.70.8-0.9-1.00.7-0.8-0.80.70.8-0.80.70.80.8-0.80.80.8-0.9-0.8-0.7-0.6-0.7-0.8
Reaction time mean minus median AUC0.10.10.20.2-0.20.3-0.4-0.50.2-0.4-0.30.30.3-0.30.30.30.3-0.30.30.3-0.5-0.3-0.3-0.1-0.3-0.3
Reaction time num false alarms0.30.40.60.6-0.60.6-0.6-0.60.4-0.6-0.60.70.6-0.60.60.60.6-0.60.60.6-0.6-0.6-0.6-0.5-0.7-0.7
Reaction time num false alarms AUC0.71.01.41.0-1.01.1-1.0-1.00.8-1.1-1.11.01.0-1.00.91.01.0-1.01.01.0-1.0-1.0-1.0-0.9-1.2-1.1
Reaction time trials correct on left0.10.10.20.3-0.30.3-0.2-0.20.2-0.2-0.20.40.2-0.20.40.20.3-0.30.30.2-0.5-0.2-0.3-0.2-0.3-0.4
Reaction time trials on left0.10.10.30.3-0.30.4-0.2-0.30.3-0.3-0.20.40.3-0.30.40.30.3-0.30.30.3-0.5-0.3-0.3-0.3-0.4-0.4
Reaction time mean0.70.91.31.1-1.11.0-1.1-1.10.9-1.0-0.90.91.0-1.00.91.00.9-1.01.01.0-0.9-1.0-1.0-1.1-0.8-0.8
Reaction time mean AUC0.30.40.70.7-0.70.6-0.8-0.80.6-0.7-0.60.60.6-0.60.60.60.6-0.60.60.6-0.6-0.7-0.6-0.7-0.5-0.5
Median of all reaction times0.70.91.31.1-1.10.9-1.0-1.10.9-0.9-0.90.90.9-0.90.90.90.9-0.90.91.0-0.8-1.0-1.0-1.1-0.8-0.8
Reaction time omissions0.40.50.80.8-0.80.8-0.8-0.80.9-0.6-0.50.70.7-0.70.80.70.7-0.70.70.7-0.7-0.7-0.7-0.8-0.6-0.6
Reaction time false alarm rate0.81.11.41.1-1.11.1-1.1-1.10.8-1.1-1.11.01.1-1.10.91.11.0-1.01.01.0-0.8-1.0-1.0-0.9-1.2-1.1
Reaction time premature initiation rate0.30.41.0-0.90.9-0.60.40.4-0.80.40.4-0.6-0.50.5-0.7-0.6-0.60.6-0.6-0.60.50.50.61.00.40.4
Reaction time premature initiations0.30.41.0-0.90.9-0.60.50.5-0.80.50.5-0.6-0.60.6-0.7-0.6-0.60.6-0.6-0.60.40.60.71.00.40.4
Std. dev. reaction times1.92.63.21.7-1.71.7-1.7-1.81.6-1.6-1.61.51.6-1.61.61.61.6-1.61.61.6-1.6-1.6-1.6-1.6-1.5-1.6
Reaction time trials completed0.10.10.30.3-0.30.4-0.2-0.30.3-0.3-0.20.40.3-0.30.40.30.3-0.30.30.3-0.5-0.3-0.3-0.3-0.4-0.4
Reaction time trials AUC0.10.10.30.3-0.30.4-0.2-0.30.3-0.3-0.20.40.3-0.30.40.30.3-0.30.30.3-0.5-0.3-0.3-0.3-0.4-0.4
Run reversals in cocaine runway, females0.00.00.0-0.10.10.0-0.00.00.00.0-0.0-0.1-0.00.0-0.1-0.0-0.00.0-0.0-0.00.00.00.00.0-0.1-0.1
Run reversals in cocaine runway, males0.50.50.70.6-0.60.8-0.8-0.80.8-0.8-0.70.70.7-0.70.70.70.7-0.70.70.7-0.8-0.7-0.7-0.5-0.8-0.8
Latency to leave start box in cocaine runway0.40.40.6-0.60.6-0.60.80.7-0.50.70.7-0.6-0.60.6-0.6-0.6-0.60.6-0.6-0.60.70.60.60.50.50.6
Latency to leave start box in cocaine runway, F0.10.10.2-0.20.2-0.20.40.3-0.20.30.4-0.2-0.30.3-0.2-0.3-0.30.3-0.3-0.30.30.30.30.10.20.2
Latency to leave start box in cocaine runway, M0.40.40.5-0.70.7-0.60.60.6-0.40.60.5-0.6-0.60.6-0.6-0.6-0.60.6-0.6-0.60.70.60.60.60.60.6
Std. dev. time between licks in bursts0.00.00.00.0-0.00.0-0.1-0.1-0.0-0.0-0.00.10.0-0.00.10.00.1-0.00.00.0-0.1-0.1-0.1-0.1-0.1-0.1
Total sessions with >9 infusions1.51.62.7-1.41.4-1.51.21.1-1.61.21.1-1.3-1.21.2-1.3-1.2-1.21.2-1.2-1.21.21.21.31.41.11.1
Short access day 1 total inactive lever presses0.10.10.30.4-0.30.2-0.4-0.4-0.2-0.4-0.50.40.4-0.40.40.40.4-0.40.40.4-0.4-0.4-0.4-0.2-0.4-0.4
Short access day 10 total inactive lever presses2.22.43.11.5-1.51.5-1.7-1.61.1-1.6-1.81.61.6-1.61.61.61.6-1.61.61.6-1.7-1.6-1.6-1.3-1.6-1.6
Short access day 1 total infusions0.00.00.00.1-0.10.0-0.2-0.2-0.1-0.1-0.00.10.1-0.10.20.10.1-0.10.10.1-0.2-0.1-0.2-0.10.00.0
Short access day 10 total infusions0.10.10.5-0.50.5-0.40.20.2-0.70.20.3-0.2-0.30.3-0.3-0.3-0.20.3-0.3-0.30.10.30.30.60.20.1
Short access total infusions0.00.00.1-0.10.1-0.1-0.0-0.0-0.4-0.00.10.0-0.00.0-0.0-0.00.00.0-0.0-0.0-0.10.00.00.2-0.0-0.1
Short access day 1 locomotion0.20.20.40.5-0.50.5-0.5-0.50.2-0.5-0.50.50.5-0.50.50.50.5-0.50.50.5-0.6-0.5-0.5-0.3-0.6-0.6
Short access day 10 total locomotion0.20.20.40.5-0.50.5-0.5-0.50.7-0.3-0.10.50.4-0.40.60.40.5-0.40.40.4-0.6-0.4-0.5-0.5-0.2-0.2
Short access total locomotion0.20.20.4-0.60.6-0.50.30.3-0.60.30.4-0.3-0.40.4-0.3-0.4-0.30.4-0.4-0.40.10.40.30.60.40.4
One hour access (0.3 mA shock)0.00.00.1-0.00.00.1-0.3-0.3-0.3-0.3-0.10.20.2-0.20.20.20.2-0.20.20.2-0.3-0.2-0.20.2-0.2-0.3
Compulsive drug intake5.15.15.72.4-2.42.4-2.3-2.32.2-2.3-2.32.22.3-2.32.12.32.2-2.22.22.3-2.1-2.3-2.2-2.3-2.3-2.3
One hour access (shock baseline)2.32.63.6-1.81.9-1.81.51.5-1.91.51.6-1.5-1.61.6-1.6-1.6-1.51.6-1.6-1.61.51.61.61.91.61.5
Social response proportion0.60.61.21.0-1.00.8-0.7-0.70.9-0.6-0.50.90.7-0.71.00.70.8-0.70.70.7-0.8-0.7-0.8-1.1-0.5-0.5
Social responses0.70.91.2-0.90.9-0.91.11.0-0.91.01.0-0.9-1.01.0-0.9-1.0-1.01.0-1.0-1.01.01.01.00.90.80.9
Social time0.00.10.2-0.10.1-0.20.20.2-0.00.30.3-0.3-0.30.3-0.2-0.3-0.30.3-0.3-0.30.30.30.20.10.30.4
Soleus weight0.10.20.3-0.50.5-0.50.50.5-0.50.50.5-0.5-0.50.5-0.4-0.5-0.50.5-0.5-0.50.50.50.50.40.50.5
Bone: stiffness0.10.10.2-0.40.4-0.40.40.4-0.40.40.3-0.3-0.40.4-0.3-0.4-0.30.4-0.4-0.40.30.40.40.40.30.3
Tibialis anterior weight8.228.030.95.6-5.55.6-5.3-5.35.2-5.3-5.45.25.3-5.35.25.35.2-5.35.35.3-5.3-5.2-5.2-5.1-5.3-5.3
Time to tail flick, vehicle, before self-admin2.12.12.41.6-1.61.5-1.5-1.41.5-1.5-1.51.41.5-1.41.41.51.4-1.41.41.4-1.4-1.4-1.4-1.5-1.4-1.3
Time to tail flick, vehicle, after self-admin1.81.92.61.5-1.51.6-1.3-1.41.6-1.3-1.31.51.3-1.31.51.31.4-1.41.41.3-1.4-1.3-1.4-1.3-1.3-1.3
Time to tail flick, test, before self-admin0.20.20.20.5-0.50.4-0.4-0.50.3-0.4-0.40.40.4-0.40.40.40.4-0.40.40.4-0.4-0.4-0.4-0.4-0.3-0.2
Time to tail flick, test, after self-admin0.10.10.10.2-0.20.3-0.3-0.30.1-0.3-0.20.30.3-0.30.20.30.3-0.30.30.3-0.3-0.3-0.2-0.1-0.3-0.3
Delta time to tail flick, vehicle, before/after SA0.30.30.4-0.50.5-0.50.60.5-0.40.60.7-0.5-0.60.6-0.4-0.6-0.50.5-0.5-0.50.50.50.50.50.60.6
Delta time to tail flick, test, before/after SA0.20.20.60.4-0.40.5-0.5-0.40.3-0.5-0.50.40.5-0.40.30.40.4-0.40.40.4-0.4-0.4-0.4-0.3-0.7-0.8
Tibia length2.46.77.6-2.82.8-2.72.72.6-2.52.62.5-2.5-2.62.6-2.5-2.6-2.62.6-2.6-2.62.52.62.62.62.52.5
Ambulatory time before self-admin0.10.10.3-0.50.5-0.20.10.1-0.10.10.1-0.3-0.20.2-0.3-0.2-0.20.2-0.2-0.20.20.20.30.50.10.1
Ambulatory time after self-admin0.80.91.90.6-0.61.0-1.0-1.10.8-1.2-1.40.81.0-1.00.61.00.9-0.90.90.9-0.9-1.0-0.8-0.4-1.3-1.3
Bone: tissue strength0.60.50.70.8-0.80.8-0.7-0.60.8-0.7-0.80.70.7-0.70.70.70.7-0.70.70.7-0.7-0.7-0.7-0.7-0.8-0.7
Total heroin consumption0.91.11.6-1.11.1-1.11.01.0-0.91.11.3-0.9-1.01.0-0.8-1.0-1.01.0-1.0-1.00.91.00.90.91.31.3
Bone: trabecular number0.00.00.1-0.20.2-0.20.20.2-0.30.20.1-0.2-0.20.2-0.2-0.2-0.20.2-0.2-0.20.20.20.20.20.20.2
Bone: trabecular spacing0.00.00.1-0.10.1-0.10.20.2-0.10.20.2-0.1-0.20.2-0.1-0.2-0.20.2-0.2-0.20.20.20.10.10.10.1
Bone: trabecular thickness0.10.10.2-0.30.3-0.20.30.3-0.20.30.3-0.2-0.30.3-0.2-0.3-0.20.2-0.2-0.20.20.30.20.20.30.4
Bone: trabecular tissue density16.723.526.2-5.15.1-5.14.94.9-4.74.84.8-4.8-4.84.8-4.8-4.8-4.84.8-4.8-4.84.84.84.84.84.84.8
Water consumed over 24 hours0.20.20.20.5-0.50.5-0.4-0.40.4-0.5-0.50.40.5-0.40.40.40.4-0.40.40.4-0.4-0.4-0.4-0.4-0.4-0.4
Number of responses in last shaping day0.10.10.4-0.40.5-0.30.20.2-0.60.10.0-0.3-0.20.2-0.4-0.2-0.30.3-0.3-0.30.20.20.30.70.1-0.0