Hub : Genes

Flrt1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XR_010056413.1 0.04 0.03 3.2e-03 0 0.01 0.01 0.01 6.0e-02 1.4e-02 7.2e-03 7.6e-03
2 BLA isoform ratio NM_001109160.1 0.14 0.07 1.5e-07 0.13 0.14 0.13 0.13 1.4e-07 8.4e-08 2.0e-07 2.2e-07
3 BLA alternative polyA NM_001109160.1 0.17 0.08 8.0e-09 0.14 0.14 0.13 0.14 9.4e-08 4.2e-08 3.6e-07 4.8e-08
4 BLA alternative polyA XM_063271593.1 0.15 0.07 5.1e-08 0.13 0.13 0.1 0.13 2.2e-07 2.5e-07 3.2e-06 2.5e-07
5 PL gene expression Flrt1 0.03 0.03 8.0e-03 0.03 0.02 0.03 0.02 8.2e-04 3.0e-03 7.8e-04 1.0e-03
6 pVTA isoform ratio XM_063271593.1 0.03 0.02 5.9e-03 0.02 0.01 0 0.01 4.3e-03 7.5e-02 1.9e-01 5.0e-02
7 IC alternative TSS NM_001109160.1 0.11 0.08 4.2e-03 0.02 0.03 -0.01 0.01 6.5e-02 2.2e-02 9.4e-01 8.9e-02
8 IC alternative TSS XM_063271593.1 0.11 0.08 3.3e-03 0.02 0.03 -0.01 0.02 5.3e-02 1.6e-02 7.6e-01 6.3e-02
9 Liver gene expression Flrt1 0.13 0.07 2.6e-09 0.05 0.07 0.06 0.06 2.2e-06 3.2e-08 2.1e-07 4.7e-07
10 PL isoform ratio XM_063271593.1 0.04 0.02 4.5e-04 0.03 0.02 0.02 0.02 4.9e-04 2.1e-03 3.7e-03 4.8e-03
11 pVTA isoform ratio NM_001109160.1 0.08 0.04 2.3e-07 0.08 0.09 0.09 0.09 3.2e-07 1.7e-07 9.7e-08 1.1e-07
12 NAcc isoform ratio XM_063271593.1 0.05 0.03 1.1e-08 0.07 0.05 0.06 0.06 1.2e-10 2.4e-08 2.7e-09 1.8e-09
13 PL mRNA stability Flrt1 0.02 0.02 5.1e-03 0.03 0.01 0.02 0.02 1.7e-04 1.1e-02 1.8e-03 3.1e-03
14 Brain alternative polyA XM_063271593.1 0.07 0.04 1.7e-05 0.05 0.04 0.04 0.04 3.4e-05 4.9e-05 4.8e-05 5.7e-05
15 PL isoform ratio NM_001109160.1 0.06 0.03 8.1e-07 0.05 0.06 0.05 0.05 1.7e-06 7.9e-07 3.3e-06 3.3e-06
16 Brain alternative polyA NM_001109160.1 0.08 0.05 4.2e-06 0.05 0.05 0.05 0.05 1.1e-05 1.3e-05 2.3e-05 1.4e-05
17 NAcc mRNA stability Flrt1 0.04 0.03 7.6e-06 0.01 0.02 0.03 0.02 6.6e-03 1.1e-04 3.9e-05 1.0e-04
18 NAcc gene expression Flrt1 0.05 0.02 5.3e-08 0.06 0.04 0.04 0.05 7.5e-09 1.8e-07 2.1e-07 1.3e-07
19 Brain isoform ratio NM_001109160.1 0.09 0.07 2.4e-05 0.04 0.02 0.05 0.03 6.4e-05 2.5e-03 2.5e-05 8.5e-04
20 Brain alternative TSS NM_001109160.1 0.05 0.03 7.1e-03 0.04 0.02 0.01 0.03 9.8e-05 3.6e-03 8.6e-02 4.7e-04
21 Brain alternative TSS XM_063271593.1 0.05 0.03 7.7e-03 0.04 0.02 0.01 0.03 1.1e-04 3.7e-03 8.3e-02 4.7e-04
22 pVTA mRNA stability Flrt1 0.06 0.03 1.0e-05 0.06 0.06 0.05 0.06 1.3e-05 1.9e-05 7.0e-05 1.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.40.73.20.30.70.6-0.80.4-0.8-0.70.70.8-0.91.0-1.0-0.4-0.71.10.7-1.7-0.8-0.0-0.50.5-1.8
Area under the delay curve0.10.21.0-0.40.10.10.10.0-0.20.0-0.1-0.3-0.00.30.1-0.4-0.40.50.3-0.4-0.5-0.40.7-0.7-1.0
BMI with tail2.17.126.4-0.71.91.8-2.61.6-2.7-2.22.22.4-2.73.0-2.5-2.4-2.13.12.4-4.4-1.9-4.5-0.20.2-5.1
BMI without tail0.82.56.20.51.51.4-1.51.3-1.6-1.31.30.9-1.51.9-1.5-1.8-1.92.22.0-2.0-0.3-1.71.1-1.1-2.5
Body weight2.611.220.50.83.33.2-3.83.0-3.7-3.53.53.3-3.74.0-3.6-3.5-3.64.13.6-4.5-0.1-3.80.2-0.2-4.2
Weight adjusted by age1.11.72.71.01.51.5-1.51.4-1.7-1.61.61.6-1.51.4-1.2-1.3-1.31.31.4-1.31.00.2-0.80.8-0.0
Bone surface3.76.713.32.32.62.6-3.02.3-3.0-2.72.73.2-3.13.1-3.2-2.1-2.22.82.1-3.6-0.10.4-2.12.1-2.6
Bone volume1.42.56.61.01.31.3-1.71.0-1.7-1.51.52.1-1.81.8-1.9-0.8-1.01.50.9-2.6-0.80.1-2.12.1-2.1
Breakpoint value in progressive ratio session3.23.85.72.42.32.3-2.22.3-2.2-2.22.22.2-2.32.1-2.4-2.1-1.82.11.9-1.81.30.4-1.01.0-0.8
Number of licking bursts0.20.20.50.60.50.5-0.60.6-0.6-0.50.50.6-0.70.5-0.6-0.6-0.40.50.4-0.60.40.1-0.30.3-0.2
Context. condit. distance diff. score1.11.42.8-1.7-1.4-1.41.4-1.31.31.3-1.3-1.41.4-1.21.40.71.0-1.0-1.00.9-1.1-1.10.6-0.6-0.2
Locomotion velocity, session 10.20.21.2-0.10.0-0.0-0.00.10.30.3-0.3-0.6-0.00.0-0.1-0.4-0.40.40.4-0.6-0.3-0.21.0-1.0-1.1
Locomotion distance, session 10.40.53.1-0.30.30.3-0.50.2-0.2-0.20.2-0.0-0.40.6-0.6-0.5-0.80.90.7-1.6-0.8-1.10.7-0.7-1.8
Locomotion velocity, session 21.92.24.30.51.61.6-1.71.5-1.6-1.61.61.5-1.71.7-1.5-1.6-1.71.81.7-2.10.4-0.9-0.00.0-1.4
Locomotion distance, session 20.40.51.50.40.70.6-0.60.5-0.5-0.40.40.0-0.60.7-0.6-0.7-1.01.11.0-1.2-0.1-0.41.1-1.1-1.2
Locomotion velocity, session 31.21.45.7-2.3-1.1-1.10.8-1.30.90.8-0.8-0.80.9-0.50.70.50.5-0.2-0.5-0.8-2.3-2.40.5-0.5-1.9
Locomotion distance, session 30.10.21.7-0.7-0.2-0.20.1-0.30.20.1-0.1-0.20.1-0.10.00.0-0.00.1-0.0-0.2-0.5-1.30.5-0.5-0.4
Stereotopy head waving bouts, day 31.21.44.0-1.8-1.3-1.31.2-1.51.11.3-1.3-1.41.1-0.71.00.80.7-0.4-0.6-0.3-2.0-1.10.9-0.9-1.8
Stereotopy head waving duration, day 30.81.02.0-1.3-1.2-1.21.2-1.31.11.1-1.1-1.01.1-0.90.91.01.0-0.8-0.90.3-1.4-0.70.2-0.2-0.7
Locomotion velocity, session 70.80.93.2-1.8-1.0-1.10.9-1.10.80.9-0.9-0.81.0-0.71.00.70.8-0.5-0.8-0.4-1.6-1.00.1-0.1-1.1
Locomotion distance, session 70.30.31.3-0.7-0.4-0.40.4-0.50.40.5-0.5-0.80.3-0.10.40.1-0.20.20.1-0.3-0.6-0.81.1-1.1-1.0
Stereotopy head waving bouts, day 70.30.31.3-0.6-0.2-0.20.0-0.0-0.2-0.10.10.5-0.00.10.0-0.30.5-0.1-0.5-0.7-0.9-0.5-1.11.1-0.9
Stereotopy head waving duration, day 70.81.02.40.00.90.9-1.01.0-1.2-1.21.21.5-1.01.1-1.0-1.1-0.50.80.5-1.3-0.1-0.8-1.31.3-0.9
Locomotion velocity, session 81.01.22.41.51.21.1-1.11.3-0.9-0.50.50.1-1.01.1-0.7-1.5-1.51.51.4-1.10.51.40.9-0.9-1.2
Locomotion distance, session 80.40.62.8-0.9-0.7-0.80.5-0.60.60.9-0.9-0.90.6-0.30.6-0.00.4-0.1-0.4-0.8-1.7-0.60.3-0.3-1.6
Degree of sensitization distance0.20.21.7-0.9-0.3-0.40.3-0.40.20.3-0.3-0.40.3-0.00.5-0.00.00.10.0-0.5-0.8-0.30.4-0.4-1.3
Degree of sensitization stereotypy0.60.72.0-0.10.60.6-0.80.7-0.9-0.90.91.3-0.80.8-0.6-0.8-0.10.50.1-1.2-0.3-0.4-1.41.4-0.8
Conditioned locomotion1.11.32.41.11.31.3-1.31.3-1.3-1.11.10.9-1.41.3-1.2-1.5-1.41.41.3-1.10.60.20.4-0.4-0.9
Cocaine response after cond. corrected1.21.53.1-1.5-1.3-1.41.5-1.41.31.4-1.4-1.81.4-1.11.41.10.9-0.9-0.70.9-1.1-0.51.3-1.3-0.4
Cocaine response after cond. not corrected0.80.91.8-1.1-1.1-1.11.2-1.21.01.1-1.1-1.31.1-0.71.01.10.7-0.6-0.50.7-1.0-0.70.9-0.9-0.4
Cocaine response before conditioning0.91.02.41.21.11.1-1.20.8-1.0-1.31.31.5-1.10.9-1.3-0.3-0.70.70.6-0.70.8-0.2-1.31.30.4
Saline control response3.95.27.61.92.72.7-2.52.6-2.6-2.72.72.3-2.82.6-2.6-2.7-2.72.62.7-1.82.0-0.40.0-0.0-0.8
Bone: connectivity density1.93.06.51.31.81.8-2.01.5-2.0-1.81.82.0-2.12.2-2.1-1.4-1.82.11.7-2.6-0.0-0.1-0.70.7-2.0
Bone: cortical apparent density0.20.32.00.50.50.5-0.30.7-0.3-0.50.50.4-0.30.1-0.2-0.4-0.3-0.00.30.61.40.5-0.00.01.4
Bone: cortical area0.60.92.2-0.10.90.9-1.00.8-1.0-1.21.21.5-1.11.0-1.1-0.9-0.70.80.7-1.10.2-0.8-0.90.9-0.5
Bone: cortical porosity0.20.21.01.00.50.5-0.30.7-0.4-0.30.30.2-0.30.3-0.3-0.7-0.30.30.3-0.00.50.8-0.10.10.4
Bone: cortical porosity0.50.61.71.30.90.9-0.81.1-0.8-0.70.70.5-0.80.8-0.8-1.1-0.80.80.8-0.50.60.6-0.10.10.0
Bone: cortical thickness2.74.47.81.62.52.5-2.32.5-2.3-2.62.62.1-2.32.2-2.3-2.3-2.42.02.4-0.72.8-0.20.7-0.70.9
Bone: cortical thickness0.70.82.60.80.90.9-0.70.8-0.7-0.70.70.1-0.60.8-0.6-0.8-1.31.01.3-0.11.10.41.6-1.60.0
Bone: cortical tissue density0.30.52.30.70.60.7-0.50.9-0.5-0.70.70.5-0.40.3-0.4-0.6-0.50.20.50.61.50.60.0-0.01.4
Condit. Reinf. active minus inactive responses0.20.21.10.10.40.5-0.50.7-0.5-0.70.70.6-0.30.4-0.3-1.0-0.50.40.6-0.10.40.5-0.20.20.0
Condit. Reinf. active-inactive response ratio0.20.31.00.50.40.4-0.40.7-0.3-0.50.50.4-0.10.2-0.1-0.8-0.30.00.30.60.81.0-0.20.20.8
Condit. Reinf. active responses0.10.10.4-0.7-0.1-0.0-0.10.0-0.1-0.30.40.40.10.10.1-0.3-0.0-0.00.0-0.2-0.30.3-0.60.6-0.1
Condit. Reinf. inactive responses0.40.41.9-1.2-0.6-0.70.5-0.90.40.5-0.5-0.20.5-0.30.50.70.6-0.4-0.6-0.6-1.4-0.4-0.60.6-0.8
Incentive salience index mean0.30.31.1-0.10.50.5-0.60.6-0.6-0.80.80.7-0.50.7-0.5-1.1-0.70.60.7-0.60.0-0.1-0.10.1-0.5
Condit. Reinf. lever presses0.40.51.4-0.20.50.5-0.80.4-0.8-0.90.91.0-0.80.9-0.9-0.6-0.40.70.6-1.2-0.3-0.8-0.60.6-0.8
Condit. Reinf. active minus inactive responses0.30.32.1-0.2-0.4-0.40.3-0.20.30.2-0.20.20.3-0.30.20.30.7-0.6-0.8-0.0-0.7-0.1-1.41.40.1
Condit. Reinf. active-inactive response ratio1.31.54.4-0.9-1.3-1.30.9-1.10.91.0-0.9-0.31.0-0.90.91.11.5-1.2-1.60.0-2.10.5-2.12.1-0.4
Condit. Reinf. active responses0.10.20.70.00.20.2-0.40.4-0.3-0.40.50.7-0.30.2-0.3-0.50.00.0-0.1-0.40.1-0.4-0.80.80.1
Condit. Reinf. inactive responses0.71.02.60.71.11.1-1.01.1-0.8-1.01.00.6-1.00.8-0.8-1.4-1.21.01.1-0.31.6-0.81.0-1.00.2
Condit. Reinf. lever presses1.42.04.60.81.41.4-1.61.4-1.6-1.61.62.0-1.71.6-1.6-1.3-0.81.30.8-2.10.3-0.1-1.51.5-1.0
Condit. Reinf. lever reinforcers received0.30.41.10.30.60.6-0.70.7-0.6-0.80.81.0-0.70.5-0.7-0.7-0.20.30.2-0.60.4-0.4-1.01.00.1
Conditioned reinforcement - actives0.20.42.60.2-0.2-0.2-0.1-0.20.20.1-0.10.7-0.1-0.20.00.40.7-0.5-0.9-0.7-0.70.2-1.61.6-0.4
Conditioned reinforcement - inactives2.43.59.1-3.0-2.1-2.01.9-2.21.91.3-1.3-0.41.5-2.01.52.12.5-2.3-2.50.9-1.5-1.9-1.61.60.5
Conditioned locomotion7.69.918.7-4.3-3.7-3.73.5-3.73.63.1-3.1-2.43.3-3.73.53.63.8-3.8-3.82.4-2.2-1.6-0.20.21.4
Patch foraging indifference point 0 sec0.10.23.4-0.5-0.2-0.2-0.0-0.20.2-0.30.30.40.1-0.2-0.2-0.00.2-0.3-0.20.80.0-1.8-0.40.40.3
Patch foraging indifference point AUC2.23.25.71.72.02.0-2.42.0-2.0-2.12.12.4-2.01.7-1.6-1.7-1.61.51.4-1.71.30.3-2.02.0-0.0
Delay disc. indifference point, 0s delay0.50.64.2-0.3-0.3-0.40.1-0.30.20.8-0.8-1.00.40.10.30.0-0.30.40.1-0.7-1.3-0.11.1-1.1-2.0
Delay disc. indifference point, 16s delay0.70.83.6-1.9-0.9-0.90.9-1.00.80.4-0.4-0.20.8-0.80.90.70.9-0.9-1.10.6-0.7-1.6-0.40.40.3
Delay disc. indifference point, 2s delay0.20.21.2-0.6-0.3-0.30.2-0.30.00.5-0.5-0.40.20.00.50.30.10.1-0.1-0.5-1.10.6-0.10.1-1.0
Delay disc. indifference point, 24s delay0.10.20.8-0.40.10.10.1-0.10.1-0.20.1-0.10.0-0.00.1-0.3-0.30.10.20.40.8-0.60.9-0.90.4
Delay disc. indifference point, 4s delay0.40.42.0-0.60.10.10.10.2-0.2-0.0-0.0-0.50.10.40.1-0.7-0.60.60.6-0.4-0.2-1.31.4-1.4-0.9
Delay disc. indifference point, 8s delay0.20.31.40.60.20.10.20.2-0.20.3-0.4-0.7-0.10.3-0.0-0.4-0.50.60.5-0.1-0.20.71.2-1.2-0.9
Indifference point function ln k5.39.216.0-2.5-3.4-3.43.7-3.53.63.6-3.6-4.03.5-3.33.23.12.6-2.8-2.73.4-2.00.52.4-2.40.7
Indifference point function log k5.39.216.0-2.5-3.4-3.43.7-3.53.63.6-3.6-4.03.5-3.33.23.12.6-2.8-2.73.4-2.00.52.4-2.40.7
Patch foraging total patch changes 0 sec0.10.33.6-0.2-0.00.0-0.1-0.00.2-0.40.40.30.0-0.1-0.3-0.2-0.1-0.10.01.00.5-1.90.0-0.00.5
Patch foraging total patch changes 12 sec4.35.68.91.72.72.7-3.02.4-2.4-3.03.03.0-2.82.5-2.8-2.4-2.52.42.2-1.81.9-2.1-0.90.9-0.9
Patch foraging total patch changes 18 sec0.81.22.31.21.21.2-1.51.3-1.1-1.41.41.5-1.21.0-1.1-1.2-1.00.90.9-0.50.9-0.5-1.11.10.1
Patch foraging total patch changes 24 sec2.03.511.7-0.01.81.8-2.01.7-1.7-2.62.62.6-2.01.7-2.0-2.1-1.71.61.6-1.21.6-3.4-0.60.6-0.2
Patch foraging total patch changes 6 sec0.81.32.50.61.21.2-1.41.2-1.2-1.41.31.2-1.41.3-1.2-1.6-1.31.41.3-0.80.7-1.00.2-0.2-0.7
Patch foraging time to switch 0 sec0.81.66.80.41.11.1-1.21.0-1.5-1.01.01.3-1.41.6-1.3-1.2-1.01.51.1-2.6-0.7-0.4-0.50.5-2.2
Patch foraging water rate 0 sec2.24.612.6-1.9-2.3-2.22.5-2.22.51.9-1.9-1.92.4-2.72.42.12.2-2.7-2.13.60.00.20.4-0.42.6
Patch foraging water rate 12 sec4.79.718.6-3.5-3.4-3.33.9-3.33.73.1-3.1-3.53.5-3.73.52.93.0-3.4-2.84.3-0.7-1.22.0-2.02.3
Patch foraging water rate 18 sec2.33.66.3-2.5-2.1-2.02.5-2.22.21.8-1.9-2.21.9-2.02.11.81.6-1.7-1.52.2-0.6-0.91.8-1.80.9
Patch foraging water rate 24 sec2.73.98.4-1.8-2.1-2.12.6-2.12.22.0-2.1-2.22.2-2.22.32.11.9-2.1-1.72.9-0.6-0.11.0-1.01.5
Patch foraging water rate 6 sec3.45.011.3-2.5-2.4-2.32.6-2.42.62.1-2.1-2.72.6-2.62.62.11.7-2.3-1.63.4-0.3-0.61.9-1.91.9
Seeking ratio, delayed vs. immediate footshock0.20.32.0-1.4-0.6-0.50.6-0.40.40.2-0.2-0.30.7-0.40.60.20.5-0.5-0.30.5-0.0-0.40.3-0.30.4
Distance traveled before self-admin0.81.13.0-0.20.80.8-1.00.6-0.9-1.21.21.7-1.01.1-1.1-0.7-0.60.70.5-1.7-0.3-1.1-1.51.5-0.8
Distance traveled after self-admin0.30.41.00.50.60.7-0.40.6-0.5-0.80.91.0-0.60.4-0.7-0.5-0.30.20.3-0.30.9-0.8-0.70.70.5
Extensor digitorum longus weight6.224.234.23.45.55.5-5.85.4-5.7-5.75.75.3-5.75.8-5.6-5.8-5.45.75.4-5.32.5-1.9-0.40.4-3.3
Bone: elastic displacement0.91.03.3-0.7-0.7-0.71.0-0.71.00.8-0.9-1.41.1-1.11.10.60.3-0.8-0.41.80.6-0.01.6-1.61.2
Bone: elastic work1.11.42.90.11.21.2-1.01.1-1.0-1.21.10.5-1.11.1-1.0-1.4-1.61.31.6-0.31.4-1.21.7-1.7-0.2
Bone: endosteal estimation1.12.510.8-1.9-1.7-1.81.3-1.91.31.7-1.7-1.21.2-1.01.41.41.4-0.8-1.5-0.9-3.3-0.3-0.80.8-2.6
Bone: endosteal perimeter1.63.414.0-1.8-2.0-2.11.5-2.11.51.9-1.9-1.11.4-1.31.51.72.0-1.2-2.0-0.9-3.70.6-1.61.6-2.4
Epididymis fat weight2.99.823.4-4.8-3.7-3.73.3-3.73.22.8-2.8-1.93.3-3.23.13.43.7-3.4-3.71.6-3.5-3.3-1.51.5-0.3
Delta time in closed arm before/after self-admin0.70.73.6-0.60.20.2-0.1-0.2-0.1-0.40.4-0.50.20.3-0.4-0.1-1.10.60.90.30.5-1.71.9-1.9-0.2
Delta time in open arm before/after self-admin0.90.93.20.10.60.7-0.90.9-0.9-1.11.11.7-0.90.7-0.7-0.80.00.20.2-1.00.4-0.1-1.81.80.5
Diff in mean of infusions in LGA sessions0.70.81.80.21.01.0-0.70.9-0.9-1.41.41.1-0.70.9-0.8-1.1-1.10.80.9-0.41.0-1.30.1-0.10.0
Delay discount exponential model param0.10.20.60.3-0.2-0.20.0-0.20.30.1-0.10.10.2-0.4-0.00.50.5-0.5-0.40.40.20.3-0.70.70.8
Extinction: sum of active levers before priming2.32.55.60.61.71.7-1.81.6-1.8-1.91.91.9-1.61.7-1.6-1.7-1.61.71.6-2.40.4-0.9-0.40.4-1.8
Active lever presses in extinction session 63.23.25.71.52.02.0-2.21.9-2.0-2.12.12.4-2.02.0-1.9-1.7-1.61.71.5-2.40.7-0.1-1.61.6-0.7
Bone: final force1.83.06.30.61.81.7-2.01.6-2.0-1.91.92.0-2.02.1-2.0-1.7-1.72.01.6-2.50.2-1.3-0.70.7-1.8
Bone: final moment1.82.96.10.31.71.7-1.91.5-1.9-1.91.92.0-2.02.0-2.0-1.6-1.71.91.6-2.50.2-1.6-0.70.7-1.7
Food consumed during 24 hour testing period0.20.21.10.20.10.2-0.20.2-0.2-0.30.40.7-0.40.0-0.40.00.2-0.3-0.20.20.6-0.3-1.01.00.9
Glucose2.43.87.5-2.3-2.3-2.32.0-2.52.12.4-2.4-2.22.1-1.82.12.31.7-1.5-1.80.4-2.7-0.90.4-0.4-1.1
Heart weight1.11.74.9-1.6-1.1-1.21.1-1.41.11.3-1.3-1.70.9-0.60.80.90.3-0.1-0.3-0.2-2.2-2.11.4-1.4-2.2
Delay discount hyperbolic model param0.10.20.90.2-0.2-0.10.0-0.20.30.00.00.20.1-0.4-0.00.50.5-0.5-0.40.50.40.2-0.60.60.9
Intermittent access intake day 1-15 change0.71.53.9-0.6-1.2-1.21.3-1.11.21.1-1.0-0.40.9-1.40.91.31.6-1.6-1.61.0-0.50.5-2.02.01.2
Intermittent access intake escalation0.71.44.7-0.3-1.1-1.11.1-0.91.11.0-1.0-0.30.8-1.20.81.11.5-1.5-1.50.7-0.50.8-2.22.21.1
Intermittent access intake escalation 21.31.56.1-0.9-1.1-1.11.2-1.01.10.7-0.7-0.00.9-1.20.51.11.5-1.5-1.50.7-0.6-0.8-2.52.51.1
Intermitt. access day 1 inactive lever presses0.10.53.30.5-0.3-0.30.5-0.20.50.6-0.6-0.30.4-0.70.50.40.5-0.6-0.60.7-0.01.8-1.01.00.5
Intermitt. access day 15 inactive lever presses1.93.913.4-3.7-2.1-2.11.9-2.31.91.0-1.0-0.21.8-1.91.61.92.1-2.2-2.20.5-2.1-2.9-2.22.20.1
Intermitt. access escalation Index1.92.74.4-2.0-1.8-1.82.0-1.91.91.7-1.7-1.81.7-1.91.61.91.7-1.7-1.62.1-0.5-0.21.0-1.00.9
Intermittent access day 1 total infusions3.25.115.8-4.0-2.6-2.72.0-2.72.12.3-2.3-1.72.0-1.82.32.22.3-1.8-2.3-0.3-4.0-1.3-0.00.0-1.9
Intermittent access day 15 total infusions5.07.513.0-3.5-3.2-3.32.8-3.22.93.0-2.9-1.92.7-2.82.83.13.4-3.0-3.40.8-3.6-0.7-1.71.7-0.2
Intermittent access terminal intake (last 3 days)5.16.816.4-4.0-3.0-3.02.4-3.02.52.5-2.4-1.32.3-2.32.32.73.2-2.6-3.00.1-4.0-2.1-2.12.1-1.0
Intermittent access total infusions4.95.815.5-3.8-2.8-2.92.2-2.92.32.5-2.5-1.62.2-2.22.42.52.7-2.2-2.8-0.0-3.9-1.5-1.01.0-1.2
Intermittent access day 1 locomotion2.73.411.1-3.3-2.2-2.21.7-2.31.71.8-1.8-1.31.7-1.51.61.81.9-1.5-1.9-0.1-3.0-2.00.2-0.2-1.3
Intermittent access day 15 total locomotion3.36.014.1-3.8-2.8-2.82.3-2.92.42.1-2.1-1.02.2-2.32.22.63.1-2.7-3.10.4-3.3-2.5-1.91.9-0.2
Intermittent access total locomotion7.99.427.8-5.3-3.6-3.62.9-3.72.92.7-2.6-1.42.8-2.82.83.13.6-3.1-3.60.2-4.5-3.0-2.02.0-0.9
Intermittent access standard deviation0.81.82.7-1.6-1.5-1.51.6-1.51.31.2-1.2-0.71.3-1.41.01.41.7-1.6-1.60.7-1.3-0.9-1.31.30.7
Left kidney weight0.42.15.5-2.2-1.7-1.71.5-1.71.41.5-1.5-1.01.3-1.31.41.41.6-1.2-1.50.0-2.4-1.3-0.40.4-1.1
Right kidney weight0.31.32.7-1.7-1.3-1.31.1-1.51.11.1-1.0-0.60.9-1.00.91.41.3-1.1-1.20.3-1.6-1.3-0.50.5-0.5
Cocaine induced anxiety0.10.21.10.60.20.2-0.10.2-0.1-0.20.20.5-0.1-0.00.2-0.10.00.0-0.2-0.4-0.20.4-1.11.1-0.1
Post-drug Anxiety0.40.40.90.90.70.7-0.70.6-0.6-0.70.70.8-0.60.6-0.4-0.7-0.70.60.5-0.90.10.4-0.70.7-0.5
Baseline Anxiety0.40.41.60.10.50.5-0.50.4-0.5-0.60.60.1-0.60.6-0.7-0.5-0.80.70.8-0.00.9-0.31.3-1.3-0.2
Tail length0.52.15.31.51.71.7-1.41.8-1.4-1.61.61.0-1.21.3-1.1-1.8-1.91.41.8-0.22.31.10.9-0.90.9
Length with tail1.66.911.12.23.13.1-3.03.2-2.9-3.03.02.4-2.73.0-2.7-3.3-3.33.13.2-2.22.1-0.10.7-0.7-1.0
Length without tail1.75.58.40.82.62.6-2.72.4-2.5-2.92.92.3-2.62.6-2.6-2.6-2.82.72.7-2.01.6-2.40.8-0.8-1.4
Times rat made contact with spout0.70.82.01.31.01.0-0.71.1-0.7-0.80.80.5-0.90.7-0.7-1.2-1.10.81.0-0.01.41.10.6-0.60.5
Lifetime Intake3.54.311.9-3.2-2.4-2.51.9-2.52.02.2-2.2-1.62.0-1.82.22.22.3-1.8-2.30.0-3.4-1.3-0.10.1-1.4
Liver weight, left0.71.12.4-1.2-1.2-1.21.1-0.91.21.3-1.3-1.61.2-1.01.40.60.8-0.8-0.70.4-1.10.90.9-0.9-0.4
Liver weight, right1.73.06.1-2.2-1.9-1.92.0-1.92.02.0-2.1-2.51.8-1.72.01.31.0-1.1-1.20.9-1.6-1.02.0-2.0-0.8
Locomotor activity1.42.24.8-1.1-1.4-1.41.8-1.61.81.5-1.5-2.01.5-1.61.51.51.3-1.4-1.12.20.1-1.11.6-1.61.0
Locomotor testing distance1.62.95.3-1.5-1.6-1.61.9-1.72.01.6-1.7-2.31.9-1.81.81.51.2-1.4-1.02.2-0.1-1.62.3-2.31.0
Locomotor testing rearing1.42.87.0-1.5-1.6-1.62.0-1.72.01.6-1.6-2.11.9-1.71.61.41.0-1.4-1.12.0-0.6-2.61.7-1.70.8
Locomotion in novel chamber4.65.89.0-2.9-2.9-2.92.6-2.92.82.5-2.4-1.82.4-2.62.42.83.0-2.8-3.01.8-2.3-1.7-0.70.70.8
Locomotion in novel chamber post-restriction2.43.95.8-1.5-2.3-2.32.2-2.22.22.1-2.1-1.72.3-2.22.12.42.4-2.4-2.41.7-1.80.0-1.01.01.1
Fecal boli incidents, locomotor time 10.20.42.60.50.20.1-0.30.1-0.3-0.20.20.8-0.30.2-0.20.20.3-0.1-0.3-0.7-0.30.5-1.61.6-0.2
Change in fecal boli incidents, locomotor task0.50.52.40.3-0.2-0.30.6-0.20.40.9-0.9-1.40.2-0.30.6-0.0-0.20.20.20.4-0.31.51.5-1.5-0.4
Time >=10cm from walls, locomotor time 11.21.35.4-0.5-1.1-1.10.8-0.90.71.2-1.1-0.40.6-0.60.61.01.5-0.8-1.3-0.9-2.30.8-1.81.8-1.1
Bouts of movement, locomotor time 12.02.38.52.61.61.6-1.21.8-1.2-1.61.71.7-1.60.9-1.5-1.2-0.90.61.00.42.90.7-0.90.92.0
Total resting periods, locomotor time 11.51.66.22.11.21.3-1.01.3-1.0-1.41.41.6-1.40.6-1.4-0.7-0.50.30.60.42.5-0.1-1.11.11.9
Rest time, locomotor task time 11.31.62.9-0.5-1.4-1.31.1-1.11.51.4-1.4-1.11.3-1.61.61.21.7-1.6-1.41.6-0.20.6-0.40.41.7
Distance moved, locomotor task time 10.30.53.6-0.00.50.4-0.40.5-0.6-0.40.40.4-0.60.8-1.0-0.7-0.50.80.6-1.1-0.8-0.50.1-0.1-1.9
Vertical activity count, locomotor time 10.30.82.0-0.8-1.1-1.11.2-1.01.01.1-1.1-1.10.9-0.80.60.81.0-0.8-0.90.5-1.40.10.3-0.3-0.8
Time >=10cm from walls, locomotor time 20.30.42.90.80.20.2-0.10.5-0.2-0.20.30.8-0.30.0-0.3-0.30.4-0.3-0.4-0.3-0.10.4-1.71.70.7
Bouts of movement, locomotor time 20.30.61.50.10.70.8-0.90.6-0.7-1.21.21.1-0.60.6-0.8-0.5-0.60.40.6-0.11.1-1.2-0.10.10.4
Total resting periods, locomotor time 20.20.31.6-0.00.40.5-0.60.4-0.4-0.80.80.8-0.40.3-0.5-0.2-0.30.20.3-0.10.7-1.3-0.30.30.4
Rest time, locomotor task time 22.12.74.5-1.1-1.9-2.01.8-1.82.02.1-2.1-1.91.6-1.81.81.82.0-1.7-1.81.3-1.50.30.0-0.00.6
Distance moved, locomotor task time 21.31.63.11.81.51.5-1.31.6-1.4-1.41.41.3-1.31.3-1.6-1.5-1.31.21.3-0.71.30.3-0.30.3-0.2
Vertical activity count, locomotor time 20.20.21.00.60.20.30.10.20.0-0.10.1-0.30.1-0.00.0-0.2-0.30.10.30.70.91.00.9-0.90.6
Light reinforcement 10.10.21.20.3-0.2-0.20.3-0.10.4-0.00.00.00.1-0.4-0.0-0.00.2-0.5-0.30.90.4-0.4-0.40.41.1
Light reinforcement 21.52.34.6-2.1-1.6-1.61.5-1.81.51.0-1.0-0.21.3-1.51.11.81.8-1.8-2.00.4-1.6-1.4-2.12.10.5
Bone: marrow area1.22.611.0-2.0-1.8-1.91.4-1.91.41.8-1.8-1.31.3-1.11.51.41.5-0.9-1.5-0.8-3.3-0.2-0.60.6-2.6
Bone: maximum diameter0.30.63.4-0.10.20.2-0.50.1-0.5-0.50.51.1-0.60.5-0.7-0.10.10.2-0.2-1.1-1.0-0.3-1.81.8-1.0
Bone: maximum force2.54.412.70.21.91.8-2.31.6-2.3-2.22.22.6-2.42.5-2.3-1.7-1.72.31.7-3.6-0.7-1.8-1.51.5-2.9
Bone: maximum moment2.44.211.8-0.01.81.8-2.21.5-2.2-2.22.22.5-2.32.4-2.3-1.7-1.72.21.7-3.4-0.6-2.1-1.41.4-2.7
Mean time between licks in bursts0.30.84.00.10.70.8-0.50.6-0.5-0.50.5-0.2-0.60.5-0.5-0.8-1.31.01.2-0.01.2-0.62.0-2.0-0.3
Mean num. licks in bursts0.10.20.70.0-0.2-0.20.4-0.20.40.3-0.3-0.60.5-0.40.50.10.0-0.3-0.10.90.40.70.6-0.60.8
Cd content in liver1.01.12.3-0.4-1.1-1.10.9-0.80.81.1-1.0-0.41.1-1.01.10.81.5-1.3-1.40.7-1.30.6-1.51.50.4
Co content in liver1.11.36.60.2-0.7-0.61.0-0.31.00.9-0.9-1.41.1-1.11.10.20.4-1.0-0.32.61.10.41.7-1.71.9
Cu content in liver0.00.00.20.3-0.0-0.00.00.10.00.0-0.0-0.00.2-0.10.20.00.1-0.2-0.10.50.10.1-0.10.10.3
Fe content in liver0.30.31.20.90.50.4-0.40.6-0.6-0.20.20.2-0.30.6-0.3-0.8-0.50.60.5-1.1-0.41.0-0.10.1-0.9
K content in liver0.80.71.80.70.80.7-0.80.7-0.8-0.70.70.4-0.71.0-0.8-1.1-1.11.21.1-0.8-0.10.70.8-0.8-1.3
Mg content in liver0.30.31.2-0.8-0.5-0.50.5-0.40.50.4-0.4-0.70.6-0.30.4-0.10.1-0.1-0.00.4-0.6-0.41.1-1.1-0.6
Mn content in liver2.52.85.81.01.81.8-1.91.6-1.8-2.12.22.4-2.01.8-2.0-1.7-1.51.51.3-1.70.9-1.1-1.31.3-0.6
Na content in liver0.40.41.00.20.60.6-0.80.7-0.7-0.80.80.7-0.60.7-0.7-1.0-0.70.60.7-0.40.5-0.30.0-0.0-0.3
Rb content in liver1.82.14.7-1.0-1.6-1.61.6-1.21.51.9-1.9-2.21.9-1.41.81.01.2-1.3-1.01.3-1.11.01.3-1.30.1
Se content in liver0.30.42.3-0.7-0.5-0.40.3-0.40.20.1-0.10.50.4-0.30.40.40.8-0.7-0.8-0.1-0.7-0.2-1.51.50.3
Sr content in liver2.52.24.41.01.71.7-1.81.5-1.6-2.02.02.1-1.71.5-1.8-1.4-1.51.31.3-0.81.5-0.9-0.80.80.1
Zn content in liver0.50.51.3-0.00.70.8-0.90.7-0.8-1.11.11.0-0.60.7-0.7-0.8-0.90.60.8-0.20.6-1.00.1-0.1-0.1
Bone: minimum diameter1.12.07.5-2.3-1.6-1.71.2-1.81.21.3-1.3-0.81.1-1.01.11.31.4-0.9-1.4-0.6-2.7-1.4-0.90.9-1.8
Time in familiar zone, hab. session 10.30.31.7-1.3-0.6-0.50.5-0.50.40.3-0.3-0.30.5-0.40.50.20.4-0.4-0.50.4-0.4-1.30.4-0.4-0.2
Time in novel zone, hab. session 10.30.31.10.5-0.3-0.30.4-0.30.60.8-0.8-1.10.5-0.50.50.4-0.0-0.10.00.3-0.11.00.9-0.90.0
Total zone transitions, hab. session 10.40.51.70.90.70.7-0.71.0-0.6-0.70.70.7-0.80.7-1.0-1.3-0.60.70.6-0.90.2-0.0-0.20.2-0.5
Total locomotion distance, hab. session 10.40.62.0-1.1-1.0-1.00.9-0.70.90.9-0.9-0.70.8-0.60.50.20.8-0.6-0.8-0.3-1.4-0.40.1-0.1-1.0
Locomotion velocity, hab. session 10.10.10.6-0.6-0.4-0.40.3-0.20.40.3-0.3-0.20.3-0.20.0-0.30.4-0.2-0.3-0.4-0.8-0.3-0.00.0-0.8
Time in familiar zone, hab. session 20.60.63.11.00.50.5-0.10.4-0.3-0.10.0-0.6-0.20.4-0.2-0.6-0.80.60.80.61.01.01.8-1.80.3
Time in novel zone, hab. session 20.40.43.2-1.1-0.2-0.2-0.1-0.20.0-0.20.20.6-0.1-0.10.00.20.3-0.2-0.3-0.7-0.7-1.8-1.11.1-0.5
Total zone transitions, hab. session 20.91.13.30.30.90.9-1.10.8-0.8-0.90.90.8-1.11.2-1.3-1.3-1.11.41.1-1.8-0.3-1.00.5-0.5-1.8
Total locomotion distance, hab. session 20.30.42.4-0.7-0.4-0.40.2-0.30.40.4-0.4-0.50.3-0.00.0-0.3-0.00.2-0.0-0.7-1.1-0.70.8-0.8-1.5
Locomotion velocity, hab. session 20.30.42.3-0.9-0.6-0.70.4-0.60.60.6-0.6-0.60.4-0.30.2-0.00.3-0.1-0.4-0.6-1.4-0.60.5-0.5-1.5
Novel to familiar place preference ratio1.21.33.80.41.01.0-1.20.7-1.4-1.41.41.9-1.31.2-1.3-0.1-0.40.80.4-1.50.0-1.0-1.81.8-0.6
Novelty place preference0.80.83.20.20.70.7-0.80.3-1.0-1.01.01.6-0.90.9-0.90.3-0.10.40.1-1.0-0.1-0.9-1.81.8-0.4
Time in novel zone, NPP test0.70.72.3-0.00.60.6-0.70.2-0.9-0.91.01.4-0.80.8-0.90.3-0.10.40.2-1.0-0.2-1.2-1.51.5-0.5
Total zone transitions, NPP test1.62.34.71.51.71.6-1.71.7-1.6-1.51.51.4-1.81.8-2.0-1.8-1.61.81.6-2.20.2-0.6-0.20.2-1.4
Total locomotion distance, NPP test0.10.21.2-0.2-0.2-0.20.1-0.10.20.3-0.3-0.40.10.1-0.1-0.3-0.10.30.1-0.7-0.9-0.40.6-0.6-1.1
Locomotion velocity, NPP test0.10.10.60.0-0.1-0.10.00.00.10.2-0.2-0.30.00.1-0.1-0.4-0.00.20.0-0.6-0.60.10.4-0.4-0.8
Intraocular pressure0.91.23.8-0.2-0.8-0.80.9-0.80.80.4-0.40.20.8-1.10.91.41.6-1.7-1.31.50.30.1-1.71.72.0
Delta distance traveled before/after self-admin0.50.52.00.4-0.2-0.10.6-0.10.50.4-0.5-0.90.5-0.50.50.00.2-0.3-0.01.31.10.31.4-1.41.2
Delta ambulatory time before/after self-admin0.40.41.90.8-0.0-0.00.40.30.20.5-0.5-1.00.3-0.30.4-0.3-0.0-0.00.20.90.90.81.4-1.40.8
Parametrial fat weight3.07.111.8-3.2-3.1-3.22.7-3.42.92.9-2.9-2.22.5-2.72.53.12.9-2.6-3.11.1-3.4-3.0-0.70.7-0.7
Pavlov. Cond. lever latency0.30.41.30.5-0.5-0.50.7-0.40.70.9-0.9-0.80.7-0.80.70.60.5-0.6-0.60.9-0.21.10.1-0.10.5
Pavlov. Cond. magazine entry latency0.40.61.3-0.20.50.5-0.70.5-0.8-0.90.91.1-0.80.8-0.9-0.7-0.40.60.4-1.1-0.2-1.1-0.60.6-0.8
Pavlov. Cond. change in total contacts0.40.42.3-0.20.10.1-0.5-0.0-0.4-0.60.61.1-0.50.3-0.40.30.3-0.1-0.2-0.7-0.2-0.5-1.51.50.1
Pavlov. Cond. index score0.40.51.2-0.00.60.6-0.80.6-0.8-1.01.01.1-0.80.7-0.8-0.6-0.40.40.4-0.60.5-0.8-0.60.60.1
Pavlov. Cond. latency score0.20.30.7-0.30.50.5-0.60.5-0.6-0.80.80.8-0.60.6-0.7-0.6-0.40.40.4-0.60.3-0.8-0.40.4-0.1
Pavlov. Cond. lever contacts0.20.31.0-0.60.30.3-0.50.3-0.5-0.60.60.5-0.50.6-0.5-0.5-0.40.50.5-0.70.0-1.00.2-0.2-0.6
Pavlov. Cond. magazine entry number0.50.61.8-0.5-0.7-0.80.8-0.80.91.1-1.1-1.30.9-0.71.00.60.3-0.4-0.40.4-0.70.41.0-1.0-0.5
Pavlov. Cond. intertrial magazine entries0.70.83.4-0.8-0.7-0.70.8-0.70.70.4-0.3-0.10.9-1.01.01.11.0-1.3-1.01.40.30.4-0.90.91.8
Pavlov. Cond. lever-magazine prob. diff.0.50.71.60.10.80.8-1.00.8-1.0-1.11.11.3-1.00.9-1.0-0.8-0.50.60.6-0.90.5-0.8-0.70.7-0.1
Pavlov. Cond. response bias0.30.41.3-0.00.50.6-0.70.5-0.7-1.01.01.2-0.80.6-0.8-0.5-0.30.30.3-0.40.5-0.8-0.70.70.2
Pavlov. Cond. lever latency0.60.82.20.1-0.7-0.70.8-0.50.81.1-1.1-1.51.0-0.81.00.40.3-0.6-0.31.4-0.10.91.4-1.40.6
Pavlov. Cond. magazine entry latency3.94.78.21.42.52.5-2.52.1-2.4-2.82.82.9-2.62.4-2.7-2.0-2.12.32.0-2.41.3-1.1-0.90.9-1.1
Pavlov. Cond. change in total contacts1.42.36.00.01.21.2-1.51.1-1.5-1.71.82.4-1.51.4-1.6-0.9-0.50.90.5-2.10.1-2.0-2.42.4-0.8
Pavlov. Cond. index score2.23.07.00.61.71.7-1.91.4-1.9-2.22.22.6-2.11.9-2.1-1.2-1.21.51.1-2.30.5-1.4-1.81.8-1.1
Pavlov. Cond. latency score1.92.66.10.51.51.5-1.71.2-1.7-2.02.02.5-1.91.7-1.9-1.0-1.01.40.9-2.30.2-1.2-1.91.9-1.2
Pavlov. Cond. lever contacts0.60.82.20.20.80.8-0.90.6-0.9-1.11.11.5-1.10.9-1.1-0.4-0.30.60.3-1.30.3-0.8-1.41.4-0.5
Pavlov. Cond. magazine entry number5.97.213.9-1.6-3.0-3.03.2-2.73.13.4-3.4-3.73.2-3.03.22.52.4-2.6-2.33.1-1.51.71.7-1.71.2
Pavlov. Cond. intertrial magazine entries0.71.02.00.1-1.1-1.11.1-0.71.11.3-1.3-1.21.1-1.11.10.71.1-1.2-1.11.4-0.61.3-0.30.30.7
Pavlov. Cond. lever-magazine prob. diff.2.73.68.10.82.01.9-2.11.6-2.1-2.42.42.8-2.32.1-2.3-1.4-1.41.71.3-2.40.7-1.5-1.81.8-1.1
Pavlov. Cond. response bias1.92.55.50.61.61.6-1.81.3-1.7-2.02.02.4-2.01.7-1.9-1.2-1.21.51.1-2.10.7-1.5-1.41.4-1.0
Time in closed arm before self-admin0.40.51.5-0.9-0.6-0.60.5-0.70.60.5-0.50.10.3-0.60.60.70.9-0.7-1.1-0.6-1.0-0.8-1.21.2-0.3
Time in closed arm after self-admin0.60.71.3-0.7-0.8-0.81.0-1.11.00.9-1.0-1.10.9-0.80.80.90.5-0.6-0.70.5-0.5-1.00.7-0.7-0.0
Time in open arm before self-admin1.11.28.70.5-0.2-0.20.4-0.10.50.6-0.7-1.70.6-0.20.3-0.1-0.70.20.71.50.80.83.0-3.00.2
Time in open arm after self-admin0.40.51.20.50.70.7-0.71.0-0.7-0.70.70.4-0.70.5-0.4-1.0-0.60.60.90.31.10.80.7-0.70.4
Bone: periosteal estimation0.40.84.1-1.3-0.5-0.60.1-0.60.10.3-0.20.30.00.00.10.30.50.0-0.5-1.4-2.0-0.6-1.21.2-2.0
Bone: periosteal perimeter0.30.52.7-0.4-0.0-0.1-0.2-0.1-0.2-0.10.10.6-0.40.4-0.4-0.10.10.3-0.2-1.3-1.4-0.2-1.21.2-1.6
Bone: post-yield work1.31.910.3-0.8-0.2-0.3-0.5-0.4-0.40.0-0.00.9-0.50.7-0.50.20.40.5-0.5-3.0-2.9-0.7-2.22.2-3.2
Progressive ratio test 1 active lever presses0.50.62.0-0.9-0.9-0.90.6-0.90.71.0-1.0-0.50.6-0.71.10.81.0-0.6-0.9-0.4-1.40.30.1-0.1-0.9
Progressive ratio test 1 breakpoint0.50.61.9-0.8-0.8-0.80.6-0.80.60.9-0.9-0.40.5-0.61.00.81.0-0.6-0.8-0.5-1.40.3-0.00.0-1.0
Progressive ratio test 1 inactive lever presses0.20.33.4-1.3-0.3-0.30.3-0.50.3-0.10.20.5-0.3-0.2-0.20.40.6-0.3-0.5-0.2-0.1-1.80.0-0.0-0.7
Progressive ratio test 2 active lever presses3.03.57.4-2.7-2.2-2.21.7-2.21.81.8-1.8-0.91.8-1.92.12.12.4-2.1-2.40.5-2.4-1.0-1.31.3-0.1
Progressive ratio test 2 breakpoint3.13.57.8-2.8-2.2-2.21.7-2.21.91.8-1.8-0.91.8-2.02.12.12.4-2.1-2.40.5-2.3-1.1-1.41.4-0.1
Progressive ratio test 2 inactive lever presses6.09.722.0-4.7-3.7-3.63.4-3.73.32.7-2.6-1.63.0-3.43.13.54.0-3.7-3.92.0-2.9-2.6-1.61.60.8
Incentive Sensitization - Responses0.60.86.0-1.5-0.4-0.40.1-0.60.2-0.10.20.70.1-0.20.00.40.4-0.4-0.7-0.5-1.3-2.5-1.61.6-0.6
Incentive Sensitization - Breakpoint0.81.06.1-1.8-0.7-0.70.3-0.90.40.1-0.00.50.4-0.40.30.60.7-0.6-0.9-0.3-1.4-2.5-1.71.7-0.4
Sum of active levers in priming session hrs 5-61.81.66.91.31.11.1-1.01.1-1.0-1.41.42.1-1.10.6-0.9-0.5-0.10.10.2-0.61.20.4-2.62.61.3
Progressive ratio0.91.46.20.70.90.8-1.31.1-1.3-0.70.71.0-1.11.4-1.2-1.3-0.81.31.0-2.5-1.00.5-0.80.8-2.0
Food seeking constrained by brief footshock0.10.10.40.20.30.3-0.10.2-0.2-0.00.0-0.2-0.30.3-0.0-0.2-0.50.40.5-0.30.2-0.30.6-0.6-0.3
Seeking ratio, punishment vs. effort1.31.85.6-1.2-1.1-1.01.5-1.31.51.0-1.1-1.61.3-1.51.51.40.5-1.1-0.72.40.7-0.91.8-1.81.6
Retroperitoneal fat weight7.431.847.4-6.5-6.7-6.76.6-6.96.66.2-6.2-5.76.3-6.26.06.46.0-6.0-6.04.9-4.9-3.50.8-0.80.9
Reaction time number correct0.20.40.90.50.70.8-0.60.7-0.7-0.90.90.7-0.70.6-0.6-0.6-0.70.50.6-0.41.00.20.2-0.2-0.0
Reaction time mean minus median1.74.26.42.52.22.2-2.22.3-2.3-2.02.02.5-2.32.2-2.5-1.9-1.61.91.5-2.40.70.9-2.42.4-0.7
Reaction time mean minus median AUC1.02.56.02.41.81.7-1.71.9-1.7-1.51.61.8-1.71.7-2.0-1.6-1.11.41.3-1.51.01.3-1.51.50.1
Reaction time num false alarms0.71.05.40.1-0.4-0.40.7-0.60.80.7-0.8-1.50.9-0.70.70.6-0.1-0.30.01.50.71.22.3-2.30.6
Reaction time num false alarms AUC0.40.74.50.70.30.30.00.10.10.0-0.0-0.80.2-0.00.0-0.0-0.70.40.70.91.11.02.1-2.10.4
Reaction time trials correct on left0.20.40.90.50.70.8-0.60.7-0.7-0.90.90.7-0.70.6-0.6-0.6-0.70.50.6-0.41.00.20.2-0.2-0.0
Reaction time trials on left0.30.51.10.60.80.9-0.70.8-0.8-0.90.90.8-0.80.6-0.7-0.7-0.80.60.7-0.41.10.20.2-0.2-0.0
Reaction time mean0.20.31.90.40.10.1-0.20.3-0.1-0.20.20.6-0.20.2-0.4-0.10.3-0.1-0.3-0.6-0.30.5-1.41.40.0
Reaction time mean AUC0.20.32.20.40.10.0-0.10.2-0.1-0.10.10.6-0.20.1-0.4-0.10.4-0.2-0.4-0.6-0.40.5-1.51.5-0.1
Median of all reaction times0.20.30.7-0.6-0.5-0.50.4-0.40.50.4-0.30.10.3-0.40.20.40.8-0.6-0.8-0.1-0.70.2-0.80.8-0.0
Reaction time omissions1.01.43.92.01.51.4-1.31.3-1.2-1.21.21.4-1.41.2-1.6-1.0-0.91.20.9-1.11.2-0.0-0.50.5-0.4
Reaction time false alarm rate0.50.73.5-0.0-0.4-0.40.6-0.50.70.7-0.7-1.30.8-0.50.60.5-0.1-0.20.11.10.30.81.9-1.90.3
Reaction time premature initiation rate2.33.26.3-0.01.91.9-2.01.8-1.7-2.02.01.2-1.71.8-1.1-2.3-2.52.22.4-1.21.8-1.11.7-1.7-0.9
Reaction time premature initiations2.74.98.60.72.52.6-2.52.5-2.3-2.72.61.8-2.32.2-1.6-2.8-2.92.62.8-1.42.7-0.61.6-1.6-0.6
Std. dev. reaction times0.71.33.92.01.11.1-1.01.3-1.1-0.90.91.2-1.01.0-1.2-0.9-0.60.70.5-1.10.51.6-1.81.80.2
Reaction time trials completed0.30.51.10.60.80.9-0.70.8-0.8-0.90.90.8-0.80.6-0.7-0.7-0.80.60.7-0.41.10.20.2-0.2-0.0
Reaction time trials AUC0.20.30.80.40.60.7-0.50.6-0.6-0.80.80.6-0.60.5-0.6-0.6-0.60.50.6-0.30.90.10.3-0.3-0.1
Run reversals in cocaine runway, females0.70.73.6-0.70.30.2-0.4-0.1-0.3-0.20.2-0.3-0.40.6-0.6-0.5-0.91.00.8-0.5-0.4-1.41.9-1.9-1.4
Run reversals in cocaine runway, males0.20.21.60.3-0.2-0.20.20.20.20.5-0.5-0.60.2-0.20.4-0.50.5-0.2-0.10.5-0.01.30.5-0.50.0
Latency to leave start box in cocaine runway0.30.41.5-0.7-0.7-0.70.5-0.60.50.7-0.7-0.60.7-0.40.70.40.4-0.4-0.5-0.6-1.20.7-0.40.4-0.5
Latency to leave start box in cocaine runway, F0.00.10.2-0.5-0.3-0.30.1-0.20.00.1-0.1-0.10.4-0.10.10.10.1-0.2-0.1-0.4-0.40.1-0.20.20.0
Latency to leave start box in cocaine runway, M0.40.42.90.3-0.3-0.40.3-0.30.30.9-0.9-0.80.2-0.30.70.10.10.0-0.3-0.6-1.11.7-0.10.1-0.9
Std. dev. time between licks in bursts0.40.53.9-0.20.00.00.3-0.20.30.2-0.2-0.90.1-0.20.1-0.0-0.60.30.50.60.8-0.52.0-2.00.1
Total sessions with >9 infusions0.30.42.5-0.0-0.4-0.50.2-0.50.30.8-0.8-0.60.3-0.20.50.50.4-0.0-0.5-0.4-1.60.60.5-0.5-1.5
Short access day 1 total inactive lever presses2.73.58.8-3.0-2.2-2.22.3-2.22.11.8-1.7-1.72.0-2.01.92.01.9-2.0-1.91.6-1.8-1.30.6-0.6-0.1
Short access day 10 total inactive lever presses0.20.61.3-0.3-0.8-0.81.0-0.70.90.9-0.9-1.11.0-1.00.80.70.5-0.8-0.51.20.10.40.0-0.01.1
Short access day 1 total infusions2.02.65.0-1.8-1.9-1.91.6-1.81.72.0-2.0-1.81.7-1.61.91.81.6-1.4-1.60.8-2.20.70.8-0.8-0.9
Short access day 10 total infusions1.31.79.8-1.7-1.3-1.40.9-1.41.01.4-1.4-0.90.9-0.71.21.21.2-0.6-1.2-0.8-3.1-0.60.2-0.2-1.9
Short access total infusions1.31.77.4-1.4-1.3-1.30.9-1.41.01.5-1.5-1.31.0-0.71.21.21.0-0.5-1.0-0.5-2.7-0.41.0-1.0-2.1
Short access day 1 locomotion1.51.94.7-2.2-1.6-1.61.4-1.81.61.3-1.3-1.01.1-1.41.11.81.5-1.4-1.60.9-1.6-1.10.2-0.2-0.7
Short access day 10 total locomotion0.91.66.5-2.5-1.4-1.41.1-1.61.11.0-1.0-0.40.9-0.90.61.31.3-1.1-1.5-0.4-1.9-2.1-0.50.5-1.0
Short access total locomotion2.02.47.1-2.7-1.8-1.81.5-2.01.51.4-1.4-0.91.2-1.31.21.71.7-1.4-1.80.2-2.3-1.9-0.40.4-0.8
One hour access (0.3 mA shock)6.57.519.2-4.4-3.2-3.22.9-3.43.02.5-2.5-1.82.6-2.92.43.13.1-3.0-3.21.6-2.7-3.1-0.90.90.2
Compulsive drug intake2.42.98.11.91.92.0-1.72.0-1.6-1.81.70.8-1.31.5-1.5-1.9-2.41.72.10.12.90.51.4-1.40.6
One hour access (shock baseline)6.19.316.6-4.1-3.6-3.63.3-3.73.43.2-3.2-2.02.7-3.32.93.63.9-3.4-3.81.4-3.5-1.8-1.51.50.2
Social response proportion0.60.61.20.90.90.9-1.11.0-1.1-0.80.80.9-0.80.9-0.6-0.9-0.70.80.7-0.80.60.8-0.20.2-0.2
Social responses0.60.71.61.11.01.0-1.11.3-1.0-0.90.90.7-0.70.9-0.5-1.2-0.70.71.0-0.11.3-0.0-0.10.10.4
Social time0.40.52.11.40.90.9-0.71.0-0.7-0.60.60.4-0.60.8-0.7-0.9-0.80.80.9-0.10.80.30.1-0.10.1
Soleus weight3.410.014.3-3.0-3.7-3.73.8-3.43.73.7-3.7-3.73.8-3.73.73.13.4-3.5-3.33.3-2.00.10.8-0.81.5
Bone: stiffness1.72.86.41.41.61.6-1.91.6-1.9-1.61.62.1-2.01.9-1.9-1.5-1.21.71.2-2.5-0.30.4-1.61.6-1.9
Tibialis anterior weight8.629.141.14.56.26.2-6.46.2-6.4-6.46.46.2-6.36.2-6.3-6.3-5.65.85.7-5.03.6-1.3-1.21.2-2.2
Time to tail flick, vehicle, before self-admin0.40.42.7-0.30.20.2-0.6-0.0-0.5-0.30.30.5-0.40.6-0.3-0.0-0.50.60.2-1.4-1.2-0.2-0.40.4-1.6
Time to tail flick, vehicle, after self-admin1.21.65.70.61.21.1-1.11.0-1.1-0.80.80.6-1.31.5-1.2-1.5-1.51.81.5-2.0-0.6-1.10.5-0.5-2.4
Time to tail flick, test, before self-admin2.42.410.8-3.0-1.6-1.61.5-1.91.51.1-1.1-1.21.2-1.11.01.31.2-0.9-1.20.6-1.8-3.31.0-1.0-1.3
Time to tail flick, test, after self-admin0.30.31.40.80.50.5-0.50.5-0.6-0.50.50.8-0.50.6-0.6-0.1-0.20.40.2-0.70.0-0.4-1.21.2-0.2
Delta time to tail flick, vehicle, before/after SA0.80.71.60.90.90.9-0.81.0-0.8-0.70.70.3-0.91.0-0.8-1.3-1.11.21.3-0.70.4-0.20.6-0.6-0.8
Delta time to tail flick, test, before/after SA2.62.77.72.81.71.7-1.51.9-1.6-1.51.61.8-1.31.1-1.1-1.0-1.10.81.0-0.42.22.6-1.71.71.8
Tibia length1.02.88.30.21.41.4-1.81.4-1.8-2.12.12.9-1.71.5-1.5-1.0-0.70.90.7-1.90.4-0.7-2.92.90.0
Ambulatory time before self-admin0.71.03.40.10.70.7-0.90.5-0.7-1.11.21.7-1.00.9-1.2-0.5-0.30.50.2-1.5-0.3-1.3-1.91.9-0.6
Ambulatory time after self-admin0.30.31.6-0.6-0.5-0.40.5-0.40.40.1-0.10.20.3-0.40.10.50.8-0.7-0.7-0.2-0.3-1.3-1.01.00.5
Bone: tissue strength0.10.10.3-0.2-0.1-0.10.1-0.20.10.1-0.10.00.2-0.20.10.30.3-0.3-0.30.10.0-0.4-0.30.30.5
Total heroin consumption4.95.88.32.72.92.9-2.62.7-2.7-2.82.82.8-2.72.7-2.8-2.4-2.32.52.5-2.22.2-0.7-1.01.0-0.7
Bone: trabecular number0.71.24.20.00.80.8-1.10.5-1.1-1.11.11.5-1.21.2-1.2-0.4-0.71.00.6-2.0-0.7-0.7-1.31.3-1.7
Bone: trabecular spacing0.60.82.80.3-0.5-0.50.8-0.30.70.7-0.7-1.20.9-0.80.90.20.3-0.6-0.21.70.71.61.4-1.41.3
Bone: trabecular thickness0.50.71.4-1.2-0.9-0.90.8-1.00.80.8-0.8-0.60.8-0.70.61.10.8-0.7-0.90.1-1.2-1.1-0.50.5-0.5
Bone: trabecular tissue density3.14.56.6-0.6-2.2-2.22.4-2.02.42.6-2.6-2.42.5-2.52.32.42.5-2.5-2.42.4-0.71.90.0-0.01.8
Water consumed over 24 hours1.01.43.41.21.41.4-1.21.5-1.2-1.41.41.1-1.31.1-1.1-1.4-1.31.01.3-0.21.80.60.2-0.20.6
Number of responses in last shaping day0.30.32.1-0.40.00.10.1-0.20.3-0.20.2-0.0-0.1-0.20.10.3-0.1-0.0-0.10.60.8-1.41.3-1.30.2