Hub : Genes

Flrt1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA alternative polyA XM_008760167.3 0.15 0.07 2.6e-07 0.11 0.11 0.1 0.11 2.1e-06 1.4e-06 8.0e-06 2.1e-06
2 BLA alternative polyA NM_001109160.1 0.16 0.08 4.2e-08 0.13 0.13 0.12 0.13 3.1e-07 1.9e-07 4.7e-07 2.9e-07
3 Brain alternative polyA NM_001109160.1 0.07 0.04 1.4e-06 0.06 0.05 0.06 0.06 3.4e-06 1.2e-05 1.2e-06 2.3e-06
4 Brain alternative polyA XM_008760167.3 0.06 0.04 4.7e-06 0.05 0.05 0.06 0.05 1.2e-05 3.3e-05 5.1e-06 8.3e-06
5 NAcc alternative polyA XM_008760167.3 0.03 0.02 3.5e-04 0.03 0.02 0.02 0.02 2.4e-04 1.2e-03 6.8e-04 1.1e-03
6 NAcc gene expression Flrt1 0.02 0.02 9.1e-03 0 0.01 0.01 0 7.7e-02 3.7e-02 4.7e-02 1.2e-01
7 Brain gene expression Flrt1 0.04 0.03 4.6e-04 0 0.02 0.01 0.01 1.8e-01 1.1e-02 2.2e-02 6.6e-02
8 Brain mRNA stability Flrt1 0.04 0.03 5.7e-03 0.01 0.01 0.02 0.02 1.9e-02 5.3e-02 2.3e-03 8.8e-03
9 LHb gene expression Flrt1 0.4 0.19 4.6e-04 0.19 0.14 0.19 0.16 3.2e-05 3.6e-04 3.5e-05 1.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.50.83.0-0.40.5-0.80.90.5-0.3-1.30.51.7
Area under the delay curve0.20.20.70.1-0.0-0.20.20.3-0.4-0.6-0.70.8
BMI with tail3.210.428.7-2.12.3-3.43.53.0-0.0-4.70.25.4
BMI without tail2.55.210.0-1.71.8-3.23.02.50.6-2.9-0.82.6
Body weight3.313.723.9-3.63.8-4.04.04.12.1-4.9-1.34.1
Weight adjusted by age1.61.82.7-1.61.6-1.51.41.51.3-1.4-0.50.4
Bone surface2.74.77.8-2.32.3-2.52.51.91.0-2.81.32.4
Bone volume1.01.73.6-1.11.1-1.21.30.70.1-1.61.81.9
Breakpoint value in progressive ratio session2.02.24.0-2.02.0-1.51.51.51.7-1.40.40.3
Number of licking bursts0.10.10.2-0.50.5-0.40.40.30.4-0.4-0.1-0.1
Context. condit. distance diff. score0.91.12.21.5-1.40.9-0.9-1.1-1.40.70.30.3
Locomotion velocity, session 10.30.31.3-0.00.1-0.30.00.5-0.3-0.6-1.01.2
Locomotion distance, session 10.81.04.7-0.30.4-0.80.60.8-0.4-1.4-0.92.2
Locomotion velocity, session 22.32.74.0-1.61.7-1.81.71.81.0-2.0-0.91.8
Locomotion distance, session 20.71.02.0-0.70.7-0.90.71.00.2-1.2-1.41.4
Locomotion velocity, session 31.21.44.81.3-1.10.1-0.1-0.5-2.0-0.70.22.2
Locomotion distance, session 30.20.20.80.3-0.30.3-0.3-0.1-0.5-0.3-0.30.9
Stereotopy head waving bouts, day 31.11.34.31.5-1.3-0.20.2-0.6-2.1-0.40.41.8
Stereotopy head waving duration, day 30.80.92.51.4-1.30.5-0.4-0.9-1.60.40.70.6
Locomotion velocity, session 70.91.02.81.3-1.20.1-0.0-1.0-1.70.10.71.1
Locomotion distance, session 70.20.30.80.6-0.5-0.20.2-0.0-0.9-0.4-0.70.8
Stereotopy head waving bouts, day 70.40.51.70.6-0.60.4-0.3-0.9-0.80.31.30.7
Stereotopy head waving duration, day 70.60.71.2-0.90.9-0.80.80.50.6-1.00.81.1
Locomotion velocity, session 81.21.42.0-1.21.2-1.41.11.30.8-1.2-1.31.1
Locomotion distance, session 80.50.73.30.8-0.7-0.30.1-0.4-1.4-0.40.21.8
Degree of sensitization distance0.30.30.80.6-0.5-0.60.7-0.1-0.9-0.40.10.8
Degree of sensitization stereotypy0.30.31.1-0.50.5-0.30.3-0.10.2-0.41.00.8
Conditioned locomotion1.11.31.8-1.31.3-1.21.21.41.0-1.3-0.70.5
Cocaine response after cond. corrected0.91.12.01.4-1.31.2-1.1-0.8-1.40.6-0.40.4
Cocaine response after cond. not corrected0.60.71.41.1-1.10.9-1.0-0.5-1.20.4-0.20.3
Cocaine response before conditioning0.50.61.3-1.11.1-0.80.70.71.1-0.50.4-0.3
Saline control response3.95.17.5-2.52.6-2.72.62.62.2-2.3-1.10.5
Bone: connectivity density1.62.65.3-1.61.6-1.71.81.60.6-2.3-0.21.9
Bone: cortical apparent density0.50.61.5-0.80.8-0.50.50.61.20.1-1.0-1.0
Bone: cortical area0.40.71.2-0.80.8-1.01.10.60.5-0.90.90.6
Bone: cortical porosity0.00.00.1-0.30.20.1-0.10.10.30.00.20.3
Bone: cortical porosity0.30.40.8-0.90.9-0.40.40.70.9-0.4-0.10.3
Bone: cortical thickness2.64.27.0-2.42.4-2.02.12.32.7-1.5-1.6-0.5
Bone: cortical thickness1.01.23.7-1.01.0-0.90.91.21.1-0.8-1.90.1
Bone: cortical tissue density0.60.81.9-0.90.9-0.50.50.71.40.0-1.1-1.1
Condit. Reinf. active minus inactive responses0.20.20.4-0.40.4-0.60.60.50.4-0.3-0.1-0.5
Condit. Reinf. active-inactive response ratio0.30.31.7-0.40.3-0.20.10.30.70.2-0.1-1.3
Condit. Reinf. active responses0.00.00.20.1-0.1-0.10.1-0.0-0.2-0.20.5-0.1
Condit. Reinf. inactive responses0.40.51.20.7-0.60.3-0.3-0.6-1.1-0.10.81.1
Incentive salience index mean0.30.30.6-0.40.5-0.80.80.70.2-0.8-0.10.3
Condit. Reinf. lever presses0.30.40.8-0.40.4-0.70.70.5-0.1-0.90.30.9
Condit. Reinf. active minus inactive responses0.60.72.80.5-0.60.7-0.8-0.8-0.60.71.7-0.3
Condit. Reinf. active-inactive response ratio2.02.17.11.3-1.31.2-1.3-1.5-1.60.92.70.1
Condit. Reinf. active responses0.00.10.4-0.10.10.0-0.1-0.10.10.10.7-0.2
Condit. Reinf. inactive responses0.81.02.1-1.01.0-1.00.91.01.1-0.6-1.4-0.1
Condit. Reinf. lever presses1.11.52.6-1.51.4-1.61.60.91.0-1.30.80.7
Condit. Reinf. lever reinforcers received0.10.10.4-0.50.5-0.20.10.20.5-0.10.7-0.2
Conditioned reinforcement - actives0.60.61.80.6-0.60.5-0.4-1.0-0.61.01.4-0.3
Conditioned reinforcement - inactives5.86.510.42.8-2.83.2-2.8-3.0-2.22.61.6-1.2
Conditioned locomotion8.510.215.23.6-3.73.9-3.5-3.6-2.83.31.8-1.7
Patch foraging indifference point 0 sec0.20.41.10.4-0.41.0-0.9-0.3-0.10.30.8-0.6
Patch foraging indifference point AUC3.33.87.8-2.32.2-2.62.81.71.9-1.60.50.6
Delay disc. indifference point, 0s delay0.80.93.30.5-0.3-0.50.50.1-1.1-0.7-1.41.8
Delay disc. indifference point, 16s delay0.80.81.31.1-1.11.1-0.8-1.2-1.00.60.6-0.1
Delay disc. indifference point, 2s delay0.20.20.70.3-0.3-0.40.4-0.0-0.8-0.4-0.00.9
Delay disc. indifference point, 24s delay0.10.10.4-0.00.1-0.10.10.40.3-0.1-0.6-0.4
Delay disc. indifference point, 4s delay0.60.74.00.1-0.0-0.0-0.00.6-0.3-0.7-2.00.9
Delay disc. indifference point, 8s delay0.20.20.8-0.10.1-0.40.30.4-0.2-0.5-0.90.6
Indifference point function ln k5.57.712.83.6-3.53.2-3.3-2.7-3.02.4-0.3-0.6
Indifference point function log k5.57.712.83.6-3.53.2-3.3-2.7-3.02.4-0.3-0.6
Patch foraging total patch changes 0 sec0.20.31.20.2-0.21.1-1.0-0.10.10.20.3-0.7
Patch foraging total patch changes 12 sec3.14.06.7-2.62.6-1.72.02.22.2-2.3-0.20.8
Patch foraging total patch changes 18 sec0.70.91.5-1.11.1-1.21.20.81.0-0.60.9-0.3
Patch foraging total patch changes 24 sec1.92.33.4-1.81.8-1.31.71.71.7-1.8-0.40.5
Patch foraging total patch changes 6 sec0.71.11.9-1.01.0-1.31.41.10.7-1.3-0.20.7
Patch foraging time to switch 0 sec1.21.83.8-1.11.2-1.71.61.10.1-1.90.31.9
Patch foraging water rate 0 sec3.25.18.72.2-2.33.0-2.7-2.1-1.12.70.6-2.4
Patch foraging water rate 12 sec5.58.415.13.2-3.23.9-3.8-2.6-2.03.2-0.4-2.1
Patch foraging water rate 18 sec2.02.74.32.1-2.02.0-2.0-1.4-1.51.5-0.7-0.7
Patch foraging water rate 24 sec3.14.310.22.1-2.13.0-3.2-1.6-1.42.00.2-1.3
Patch foraging water rate 6 sec2.43.65.62.2-2.22.4-2.4-1.5-1.32.0-0.8-1.5
Seeking ratio, delayed vs. immediate footshock0.10.10.20.4-0.40.4-0.4-0.0-0.20.3-0.1-0.2
Distance traveled before self-admin0.20.30.9-0.60.6-0.00.10.30.4-0.50.90.3
Distance traveled after self-admin0.10.20.3-0.40.40.5-0.50.00.60.10.5-0.2
Extensor digitorum longus weight5.822.832.0-5.35.4-5.55.55.43.8-5.7-1.53.3
Bone: elastic displacement0.91.01.70.8-0.81.2-1.3-0.5-0.11.2-1.3-1.0
Bone: elastic work1.01.33.6-1.11.1-0.90.81.41.2-1.0-1.90.3
Bone: endosteal estimation1.53.38.72.0-1.90.4-0.4-1.5-3.0-0.02.42.3
Bone: endosteal perimeter2.24.611.22.2-2.10.8-0.8-2.1-3.20.43.32.2
Epididymis fat weight2.76.411.02.9-2.83.3-3.2-2.4-2.91.41.51.2
Delta time in closed arm before/after self-admin0.60.63.80.2-0.10.1-0.00.7-0.1-0.7-1.90.5
Delta time in open arm before/after self-admin0.20.20.6-0.50.4-0.10.1-0.00.60.20.8-0.8
Diff in mean of infusions in LGA sessions0.60.61.5-0.90.80.7-0.80.61.2-0.2-0.9-0.5
Delay discount exponential model param0.20.20.60.0-0.10.3-0.3-0.40.30.60.7-0.7
Extinction: sum of active levers before priming3.43.35.0-2.22.2-1.81.72.11.7-2.0-0.51.4
Active lever presses in extinction session 61.51.53.1-1.81.7-1.01.11.11.7-1.00.2-0.0
Bone: final force2.23.55.7-1.91.9-2.22.21.91.0-2.40.12.2
Bone: final moment1.93.15.1-1.81.8-2.02.11.81.0-2.30.12.1
Food consumed during 24 hour testing period0.20.20.8-0.30.20.5-0.4-0.10.50.40.5-0.9
Glucose1.92.86.32.1-2.11.4-1.4-1.8-2.50.91.20.9
Heart weight2.63.76.22.5-2.42.4-2.2-1.9-2.21.50.00.0
Delay discount hyperbolic model param0.20.30.60.0-0.10.4-0.4-0.40.30.70.7-0.8
Intermittent access intake day 1-15 change1.01.02.30.5-0.61.1-1.1-1.0-0.11.31.5-1.1
Intermittent access intake escalation1.01.02.10.5-0.61.2-1.2-1.0-0.21.21.5-0.9
Intermittent access intake escalation 20.80.82.40.2-0.31.1-1.1-0.70.20.91.6-1.1
Intermitt. access day 1 inactive lever presses2.22.33.71.8-1.81.6-1.4-1.9-1.51.61.0-0.5
Intermitt. access day 15 inactive lever presses3.84.27.22.3-2.32.7-2.3-2.4-2.01.71.4-0.2
Intermitt. access escalation Index1.71.52.81.7-1.61.5-1.3-1.1-1.40.9-0.30.1
Intermittent access day 1 total infusions5.96.813.93.3-3.22.5-2.0-2.9-3.71.41.81.4
Intermittent access day 15 total infusions8.99.913.73.5-3.53.7-3.3-3.6-3.42.62.8-0.0
Intermittent access terminal intake (last 3 days)7.17.710.43.0-3.03.2-2.8-3.0-3.21.83.10.8
Intermittent access total infusions5.96.610.33.0-3.02.8-2.5-2.9-3.21.72.40.8
Intermittent access day 1 locomotion3.84.09.82.7-2.51.8-1.4-2.0-3.10.60.81.6
Intermittent access day 15 total locomotion5.25.67.92.7-2.72.8-2.4-2.7-2.61.82.1-0.0
Intermittent access total locomotion7.38.314.63.5-3.43.0-2.5-3.1-3.81.52.81.1
Intermittent access standard deviation1.92.14.31.1-1.22.0-2.1-1.4-0.71.51.4-0.9
Left kidney weight0.61.83.51.4-1.41.9-1.7-1.3-1.31.01.3-0.2
Right kidney weight0.41.02.50.9-0.91.3-1.1-1.1-0.90.61.60.4
Cocaine induced anxiety0.20.21.7-0.10.0-0.10.2-0.1-0.1-0.11.30.1
Post-drug Anxiety0.70.71.2-1.11.1-1.00.90.70.8-0.70.90.5
Baseline Anxiety1.71.82.8-1.71.7-1.00.81.51.5-1.3-1.30.8
Tail length1.33.86.0-2.12.1-2.12.02.12.5-1.2-2.1-0.9
Length with tail1.66.08.5-2.92.9-2.32.32.82.6-2.5-2.11.1
Length without tail0.92.13.7-1.61.7-0.60.81.51.2-1.9-0.81.9
Times rat made contact with spout0.80.91.4-1.01.0-0.80.71.01.2-0.5-1.2-0.7
Lifetime Intake4.95.69.32.8-2.82.7-2.4-2.6-3.01.41.60.9
Liver weight, left0.10.20.50.4-0.3-0.30.0-0.2-0.7-0.10.40.7
Liver weight, right0.50.84.50.4-0.3-0.40.30.2-0.9-0.9-0.62.1
Locomotor activity1.21.93.81.5-1.41.8-2.0-1.0-0.71.5-0.8-1.1
Locomotor testing distance1.42.44.21.8-1.72.0-2.1-1.1-1.01.5-1.5-0.9
Locomotor testing rearing1.42.25.21.7-1.62.1-2.3-1.1-1.11.3-0.9-0.5
Locomotion in novel chamber4.75.88.22.7-2.82.9-2.7-2.9-2.52.31.5-0.4
Locomotion in novel chamber post-restriction2.73.24.32.0-2.11.7-1.8-2.0-1.71.91.7-0.9
Fecal boli incidents, locomotor time 10.40.43.0-0.30.2-0.40.4-0.2-0.0-0.01.70.2
Change in fecal boli incidents, locomotor task0.50.42.30.2-0.1-0.60.40.5-0.4-0.5-1.50.7
Time >=10cm from walls, locomotor time 11.41.43.41.1-1.10.5-0.6-1.3-1.80.41.81.1
Bouts of movement, locomotor time 11.71.85.6-1.61.5-0.30.10.82.40.3-0.6-2.1
Total resting periods, locomotor time 11.21.34.0-1.41.2-0.1-0.00.62.00.4-0.5-1.8
Rest time, locomotor task time 11.11.22.81.1-1.20.7-0.9-1.1-0.61.60.3-1.7
Distance moved, locomotor task time 10.40.42.6-0.30.30.00.00.4-0.2-0.9-0.11.6
Vertical activity count, locomotor time 11.21.21.91.3-1.31.4-1.3-1.1-1.30.80.50.5
Time >=10cm from walls, locomotor time 20.20.20.6-0.20.10.3-0.4-0.40.30.50.8-0.7
Bouts of movement, locomotor time 20.30.31.0-0.70.70.00.20.61.0-0.3-0.3-0.3
Total resting periods, locomotor time 20.10.10.4-0.50.40.2-0.10.40.6-0.20.0-0.3
Rest time, locomotor task time 21.92.23.61.9-1.91.4-1.5-1.6-1.81.50.9-0.3
Distance moved, locomotor task time 20.91.02.3-1.51.4-0.60.51.01.5-0.7-0.5-0.1
Vertical activity count, locomotor time 20.30.30.9-0.30.30.3-0.60.30.80.3-1.0-0.9
Light reinforcement 10.20.41.70.3-0.30.6-0.8-0.20.20.70.1-1.3
Light reinforcement 22.33.16.51.7-1.72.0-1.8-2.1-1.51.42.6-0.1
Bone: marrow area1.53.38.92.0-1.90.4-0.4-1.6-3.00.02.22.3
Bone: maximum diameter0.40.74.5-0.20.2-0.50.5-0.2-0.4-0.62.10.8
Bone: maximum force2.64.49.7-1.71.8-2.42.51.70.4-2.81.03.1
Bone: maximum moment2.33.98.7-1.51.6-2.22.41.60.3-2.71.03.0
Mean time between licks in bursts1.01.44.4-1.01.0-0.80.81.41.1-1.1-2.10.6
Mean num. licks in bursts0.10.10.40.2-0.20.2-0.2-0.00.10.4-0.4-0.6
Cd content in liver1.21.32.60.9-1.01.2-1.2-1.4-0.81.21.6-0.5
Co content in liver1.51.75.40.6-0.71.3-1.4-0.50.41.6-1.6-2.3
Cu content in liver0.20.30.6-0.70.6-0.30.30.60.8-0.3-0.4-0.4
Fe content in liver0.20.30.7-0.40.4-0.90.80.20.1-0.40.40.6
K content in liver2.22.25.0-1.01.1-2.22.21.40.2-1.9-0.21.4
Mg content in liver0.40.41.20.2-0.2-0.70.80.1-0.8-0.80.41.1
Mn content in liver1.21.42.2-1.51.5-1.21.31.11.2-1.20.60.8
Na content in liver0.60.71.3-0.90.9-1.11.10.80.6-0.90.30.4
Rb content in liver1.11.42.71.6-1.60.8-0.9-1.3-1.60.90.40.4
Se content in liver0.40.53.40.2-0.20.3-0.2-0.7-0.30.41.8-0.3
Sr content in liver2.22.04.1-1.91.9-1.01.21.72.0-1.2-0.4-0.3
Zn content in liver0.60.61.2-1.01.0-0.50.71.00.8-1.1-0.20.3
Bone: minimum diameter1.42.56.51.8-1.70.4-0.3-1.4-2.60.02.21.8
Time in familiar zone, hab. session 10.20.20.40.6-0.60.0-0.0-0.5-0.60.10.30.4
Time in novel zone, hab. session 10.20.21.10.2-0.20.5-0.60.1-0.20.2-1.1-0.1
Total zone transitions, hab. session 10.30.40.6-0.80.8-0.80.60.70.6-0.7-0.40.5
Total locomotion distance, hab. session 10.40.61.91.0-1.00.2-0.4-0.7-1.40.10.30.9
Locomotion velocity, hab. session 10.10.10.50.5-0.4-0.1-0.0-0.2-0.7-0.10.10.6
Time in familiar zone, hab. session 20.40.42.4-0.40.5-0.40.40.70.6-0.2-1.5-0.2
Time in novel zone, hab. session 20.10.10.60.2-0.20.1-0.0-0.1-0.4-0.20.80.4
Total zone transitions, hab. session 21.11.43.4-0.90.9-1.31.21.20.1-1.7-0.71.9
Total locomotion distance, hab. session 20.40.52.10.5-0.4-0.50.40.2-1.0-0.7-0.31.5
Locomotion velocity, hab. session 20.40.62.00.7-0.6-0.30.2-0.2-1.3-0.50.11.4
Novel to familiar place preference ratio0.60.61.1-1.01.0-0.60.80.50.7-0.81.00.5
Novelty place preference0.30.31.3-0.70.6-0.30.50.20.4-0.51.20.2
Time in novel zone, NPP test0.30.30.9-0.60.5-0.20.40.20.3-0.51.00.4
Total zone transitions, NPP test1.52.23.5-1.61.7-1.61.41.60.9-1.9-0.71.7
Total locomotion distance, NPP test0.20.31.70.2-0.1-0.30.20.2-0.7-0.6-0.41.3
Locomotion velocity, NPP test0.10.20.90.1-0.0-0.30.20.1-0.4-0.4-0.40.9
Intraocular pressure1.82.55.10.8-0.92.3-2.2-1.40.02.01.0-2.2
Delta distance traveled before/after self-admin0.10.10.60.0-0.00.3-0.40.00.10.2-0.8-0.2
Delta ambulatory time before/after self-admin0.10.21.2-0.10.1-0.2-0.00.30.20.1-1.1-0.1
Parametrial fat weight1.83.48.02.3-2.21.7-1.6-1.9-2.80.71.21.1
Pavlov. Cond. lever latency0.50.61.30.4-0.51.0-1.1-0.6-0.10.9-0.1-1.1
Pavlov. Cond. magazine entry latency0.30.40.8-0.30.4-0.70.90.4-0.0-0.90.40.9
Pavlov. Cond. change in total contacts0.20.21.40.0-0.0-0.10.3-0.3-0.20.01.20.1
Pavlov. Cond. index score0.20.20.4-0.50.5-0.50.70.40.4-0.40.30.2
Pavlov. Cond. latency score0.20.20.6-0.30.3-0.60.80.40.2-0.50.10.5
Pavlov. Cond. lever contacts0.20.20.7-0.10.1-0.50.60.4-0.1-0.5-0.20.8
Pavlov. Cond. magazine entry number0.20.20.60.7-0.60.2-0.3-0.3-0.70.1-0.60.4
Pavlov. Cond. intertrial magazine entries1.21.42.80.7-0.81.5-1.5-1.1-0.01.50.9-1.7
Pavlov. Cond. lever-magazine prob. diff.0.30.40.9-0.70.7-0.80.90.60.6-0.60.30.4
Pavlov. Cond. response bias0.10.10.1-0.30.3-0.20.40.30.4-0.20.4-0.0
Pavlov. Cond. lever latency0.40.50.90.6-0.60.8-0.8-0.3-0.20.8-0.9-1.0
Pavlov. Cond. magazine entry latency2.73.14.8-2.22.2-1.81.81.91.8-1.9-0.50.9
Pavlov. Cond. change in total contacts0.71.02.2-1.21.2-0.70.80.50.8-0.91.51.0
Pavlov. Cond. index score1.31.72.7-1.61.6-1.41.41.11.2-1.50.71.1
Pavlov. Cond. latency score1.11.42.0-1.41.4-1.21.30.90.9-1.40.81.2
Pavlov. Cond. lever contacts0.20.30.6-0.80.7-0.50.50.30.6-0.50.70.1
Pavlov. Cond. magazine entry number4.04.87.72.8-2.82.3-2.4-2.2-2.32.40.1-1.3
Pavlov. Cond. intertrial magazine entries0.70.91.41.0-1.00.7-0.9-1.0-0.81.20.8-0.8
Pavlov. Cond. lever-magazine prob. diff.1.72.23.5-1.91.8-1.51.61.41.4-1.70.51.1
Pavlov. Cond. response bias1.01.32.4-1.51.5-1.11.20.91.2-1.20.50.6
Time in closed arm before self-admin0.10.20.7-0.20.2-0.40.3-0.2-0.1-0.10.80.4
Time in closed arm after self-admin0.20.20.70.5-0.40.1-0.1-0.2-0.60.0-0.90.5
Time in open arm before self-admin0.40.42.70.5-0.50.3-0.30.2-0.10.3-1.6-0.4
Time in open arm after self-admin0.30.42.0-0.10.10.4-0.40.00.70.6-0.1-1.4
Bone: periosteal estimation0.71.55.10.7-0.7-0.40.5-0.6-1.6-0.62.21.8
Bone: periosteal perimeter0.50.83.30.1-0.1-0.40.5-0.3-0.8-0.61.81.4
Bone: post-yield work2.12.98.60.5-0.5-1.31.3-0.7-2.0-1.12.92.9
Progressive ratio test 1 active lever presses3.13.24.62.1-2.12.1-1.9-2.1-1.81.90.7-0.5
Progressive ratio test 1 breakpoint2.52.63.81.9-1.91.7-1.6-1.9-1.61.80.7-0.5
Progressive ratio test 1 inactive lever presses1.31.43.21.3-1.31.8-1.5-1.2-1.00.8-0.70.0
Progressive ratio test 2 active lever presses5.05.37.82.7-2.72.6-2.2-2.8-2.52.11.7-0.3
Progressive ratio test 2 breakpoint5.86.59.42.9-3.02.9-2.5-3.1-2.52.71.7-0.9
Progressive ratio test 2 inactive lever presses9.310.717.23.7-3.74.1-3.7-3.7-3.22.82.5-0.5
Incentive Sensitization - Responses0.90.91.41.0-1.01.2-0.9-1.1-1.00.71.00.1
Incentive Sensitization - Breakpoint1.21.21.81.2-1.21.3-1.0-1.3-1.20.91.1-0.1
Sum of active levers in priming session hrs 5-60.80.82.3-1.31.10.10.00.21.50.11.1-0.9
Progressive ratio2.12.54.2-1.41.5-2.02.01.40.5-1.90.22.1
Food seeking constrained by brief footshock0.60.73.2-0.50.6-0.80.60.90.4-0.6-1.80.2
Seeking ratio, punishment vs. effort1.41.72.71.2-1.21.5-1.5-0.9-0.51.4-1.4-1.7
Retroperitoneal fat weight4.916.123.44.8-4.84.6-4.5-4.3-4.63.22.6-0.1
Reaction time number correct0.30.40.9-0.80.8-0.00.10.70.9-0.4-0.70.5
Reaction time mean minus median2.12.84.8-2.12.0-2.22.11.31.5-1.41.01.0
Reaction time mean minus median AUC1.21.62.9-1.71.6-1.51.41.11.5-0.90.30.3
Reaction time num false alarms0.30.32.30.4-0.40.3-0.3-0.00.10.5-1.5-0.4
Reaction time num false alarms AUC0.30.52.9-0.30.3-0.20.30.70.7-0.1-1.7-0.2
Reaction time trials correct on left0.30.40.9-0.80.8-0.00.10.70.9-0.4-0.70.5
Reaction time trials on left0.30.51.0-0.90.9-0.10.10.81.0-0.5-0.70.5
Reaction time mean0.10.10.9-0.10.00.1-0.1-0.40.00.30.9-0.1
Reaction time mean AUC0.10.20.9-0.0-0.00.2-0.3-0.5-0.00.31.0-0.1
Median of all reaction times0.20.30.70.4-0.50.6-0.6-0.8-0.40.50.8-0.2
Reaction time omissions0.40.61.6-1.31.2-0.30.20.61.2-0.5-0.40.1
Reaction time false alarm rate0.10.21.20.4-0.40.00.00.0-0.20.2-1.1-0.3
Reaction time premature initiation rate3.14.26.9-1.81.9-2.22.32.41.6-2.2-2.60.8
Reaction time premature initiations4.25.98.6-2.52.6-2.32.42.92.5-2.3-2.90.8
Std. dev. reaction times0.50.71.2-1.11.0-1.11.00.30.9-0.20.90.0
Reaction time trials completed0.30.51.0-0.90.9-0.10.10.81.0-0.5-0.70.5
Reaction time trials AUC0.20.30.6-0.70.60.1-0.00.70.8-0.4-0.70.6
Run reversals in cocaine runway, females1.31.23.0-0.20.4-1.11.11.0-0.3-1.6-1.41.7
Run reversals in cocaine runway, males0.00.00.10.1-0.2-0.1-0.10.1-0.10.3-0.1-0.1
Latency to leave start box in cocaine runway0.60.61.80.6-0.5-0.70.9-0.5-1.0-0.11.30.6
Latency to leave start box in cocaine runway, F0.30.31.30.1-0.1-0.60.8-0.1-0.2-0.01.2-0.1
Latency to leave start box in cocaine runway, M0.40.30.80.4-0.4-0.60.5-0.4-0.9-0.00.60.9
Std. dev. time between licks in bursts0.20.32.20.1-0.10.1-0.10.30.1-0.1-1.50.3
Total sessions with >9 infusions2.02.25.22.0-1.91.4-1.2-1.6-2.30.70.41.0
Short access day 1 total inactive lever presses4.55.08.32.7-2.72.9-2.6-2.4-2.41.90.1-0.3
Short access day 10 total inactive lever presses2.42.74.42.1-2.11.8-1.7-1.8-1.61.8-0.2-0.8
Short access day 1 total infusions3.13.35.92.3-2.32.0-1.7-2.0-2.41.10.60.7
Short access day 10 total infusions2.52.87.12.1-2.01.5-1.3-1.6-2.70.40.91.5
Short access total infusions1.92.25.11.9-1.81.5-1.2-1.5-2.30.40.21.3
Short access day 1 locomotion2.52.65.42.1-2.01.9-1.4-1.7-2.30.50.31.3
Short access day 10 total locomotion1.51.73.81.8-1.71.3-1.0-1.3-1.90.50.60.7
Short access total locomotion1.71.84.41.8-1.71.3-0.9-1.3-2.10.20.51.1
One hour access (0.3 mA shock)9.511.215.43.9-3.93.9-3.5-3.9-3.53.12.1-0.7
Compulsive drug intake4.44.412.9-2.02.1-1.91.72.12.4-1.3-3.6-0.4
One hour access (shock baseline)10.912.617.13.7-3.84.1-3.8-4.1-3.53.23.8-0.7
Social response proportion0.70.81.2-1.11.1-1.11.10.90.8-0.9-0.20.1
Social responses0.60.71.4-1.01.0-0.70.41.11.2-0.4-0.7-0.7
Social time0.50.61.1-1.00.9-0.80.61.01.0-0.5-0.7-0.4
Soleus weight3.08.813.13.6-3.63.2-3.2-3.3-3.03.11.3-1.2
Bone: stiffness1.72.74.2-1.61.6-2.02.01.30.6-2.01.21.9
Tibialis anterior weight7.726.239.3-6.26.3-5.45.35.95.1-5.6-1.52.1
Time to tail flick, vehicle, before self-admin1.11.24.1-0.50.5-1.21.30.6-0.4-1.40.22.0
Time to tail flick, vehicle, after self-admin3.73.96.7-1.61.7-2.62.52.10.7-2.4-0.92.2
Time to tail flick, test, before self-admin1.11.12.91.2-1.10.8-0.6-0.6-1.6-0.30.21.7
Time to tail flick, test, after self-admin0.10.10.2-0.40.4-0.40.30.40.3-0.20.50.1
Delta time to tail flick, vehicle, before/after SA1.11.12.2-1.01.0-1.51.41.30.7-1.1-0.60.6
Delta time to tail flick, test, before/after SA1.71.53.9-1.61.4-0.90.81.02.00.10.1-1.7
Tibia length0.51.43.1-1.51.4-1.01.20.71.1-1.01.80.6
Ambulatory time before self-admin0.10.10.3-0.40.40.4-0.3-0.10.4-0.20.60.1
Ambulatory time after self-admin0.50.62.30.5-0.50.9-0.8-0.8-0.50.51.5-0.1
Bone: tissue strength0.10.10.30.0-0.10.3-0.4-0.30.10.40.6-0.5
Total heroin consumption4.04.68.7-2.92.9-2.01.82.52.6-2.0-0.60.3
Bone: trabecular number0.40.72.7-0.40.5-0.50.70.3-0.3-1.11.11.6
Bone: trabecular spacing0.30.52.10.2-0.20.3-0.40.00.40.7-1.0-1.4
Bone: trabecular thickness0.81.01.41.1-1.11.0-1.0-1.1-1.20.60.90.6
Bone: trabecular tissue density2.53.66.32.0-2.11.9-1.9-2.2-1.42.51.0-1.6
Water consumed over 24 hours0.91.12.4-1.31.2-0.70.71.21.6-0.5-1.1-0.7
Number of responses in last shaping day1.51.64.81.2-1.12.2-2.0-1.1-0.60.9-0.2-0.6