Hub : Genes

Flrt1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XR_010056413.1 0.04 0.03 3.2e-03 0 0.01 0.01 0.01 6.0e-02 1.4e-02 7.2e-03 8.3e-03
2 BLA isoform ratio NM_001109160.1 0.14 0.07 1.5e-07 0.13 0.14 0.13 0.13 1.4e-07 8.4e-08 2.0e-07 2.1e-07
3 BLA alternative polyA NM_001109160.1 0.17 0.08 8.0e-09 0.14 0.14 0.13 0.14 9.4e-08 4.2e-08 3.6e-07 4.9e-08
4 BLA alternative polyA XM_063271593.1 0.15 0.07 5.1e-08 0.13 0.13 0.1 0.13 2.2e-07 2.5e-07 3.2e-06 2.7e-07
5 PL gene expression Flrt1 0.03 0.03 8.0e-03 0.03 0.02 0.03 0.02 8.2e-04 3.0e-03 7.8e-04 1.0e-03
6 pVTA isoform ratio XM_063271593.1 0.03 0.02 5.9e-03 0.02 0.01 0 0.01 4.3e-03 7.5e-02 1.9e-01 4.3e-02
7 IC alternative TSS NM_001109160.1 0.11 0.08 4.2e-03 0.02 0.03 -0.01 0.01 6.5e-02 2.2e-02 9.8e-01 8.9e-02
8 IC alternative TSS XM_063271593.1 0.11 0.08 3.3e-03 0.02 0.03 -0.01 0.02 5.3e-02 1.6e-02 9.1e-01 6.4e-02
9 Liver gene expression Flrt1 0.13 0.07 2.6e-09 0.05 0.07 0.06 0.06 2.2e-06 3.2e-08 2.1e-07 4.8e-07
10 PL isoform ratio XM_063271593.1 0.04 0.02 4.5e-04 0.03 0.02 0.02 0.02 4.9e-04 2.1e-03 3.7e-03 5.2e-03
11 pVTA isoform ratio NM_001109160.1 0.08 0.04 2.3e-07 0.08 0.09 0.09 0.09 3.2e-07 1.7e-07 9.7e-08 1.1e-07
12 NAcc isoform ratio XM_063271593.1 0.05 0.03 1.1e-08 0.07 0.05 0.06 0.06 1.2e-10 2.4e-08 2.7e-09 1.8e-09
13 PL mRNA stability Flrt1 0.02 0.02 5.1e-03 0.03 0.01 0.02 0.02 1.7e-04 1.1e-02 1.8e-03 3.1e-03
14 Brain alternative polyA XM_063271593.1 0.07 0.04 1.7e-05 0.05 0.04 0.04 0.04 3.4e-05 4.9e-05 4.3e-05 5.6e-05
15 PL isoform ratio NM_001109160.1 0.06 0.03 8.1e-07 0.05 0.06 0.05 0.05 1.7e-06 7.9e-07 3.3e-06 3.4e-06
16 Brain alternative polyA NM_001109160.1 0.08 0.05 4.2e-06 0.05 0.05 0.05 0.05 1.1e-05 1.3e-05 2.3e-05 1.4e-05
17 NAcc mRNA stability Flrt1 0.04 0.03 7.6e-06 0.01 0.02 0.03 0.03 6.6e-03 1.1e-04 3.6e-05 1.0e-04
18 NAcc gene expression Flrt1 0.05 0.02 5.3e-08 0.06 0.04 0.04 0.05 7.5e-09 1.8e-07 2.1e-07 1.2e-07
19 Brain alternative TSS NM_001109160.1 0.05 0.03 7.1e-03 0.04 0.02 0.01 0.03 9.8e-05 3.6e-03 8.6e-02 4.3e-04
20 Brain alternative TSS XM_063271593.1 0.05 0.03 7.7e-03 0.04 0.02 0.01 0.03 1.1e-04 3.7e-03 7.9e-02 5.5e-04
21 Brain isoform ratio NM_001109160.1 0.09 0.07 2.4e-05 0.04 0.02 0.05 0.03 6.4e-05 2.5e-03 2.3e-05 9.2e-04
22 pVTA mRNA stability Flrt1 0.06 0.03 1.0e-05 0.06 0.06 0.05 0.06 1.3e-05 1.9e-05 7.0e-05 1.7e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.40.73.2-0.30.70.60.8-0.40.8-0.70.70.80.9-1.01.00.40.71.1-0.71.70.80.5-0.50.11.8
Area under the delay curve0.10.21.00.40.10.1-0.1-0.00.20.0-0.1-0.30.0-0.3-0.10.40.40.5-0.30.40.5-0.70.70.41.0
BMI with tail2.07.126.40.71.91.82.6-1.62.7-2.22.22.42.7-3.02.52.42.13.1-2.44.41.90.2-0.24.55.1
BMI without tail0.52.56.2-0.41.51.41.5-1.31.6-1.31.30.91.5-1.91.51.81.92.2-2.02.00.3-1.11.11.82.5
Body weight2.611.220.6-0.83.33.23.8-3.03.7-3.53.53.33.7-4.03.63.53.64.1-3.64.50.1-0.20.23.84.2
Weight adjusted by age0.61.72.7-1.01.51.51.5-1.41.7-1.61.61.61.5-1.41.21.31.31.3-1.41.3-1.00.8-0.8-0.20.0
Bone surface3.46.713.3-2.32.62.63.0-2.33.0-2.72.73.23.1-3.13.22.12.22.8-2.13.60.12.1-2.1-0.32.6
Bone volume1.32.56.6-1.01.31.31.7-1.01.7-1.51.52.11.8-1.81.90.81.01.5-0.92.60.82.1-2.1-0.02.1
Breakpoint value in progressive ratio session2.13.85.7-2.42.32.32.2-2.32.2-2.22.22.22.3-2.12.42.11.82.1-1.91.8-1.31.0-1.0-0.30.8
Number of licking bursts0.10.20.5-0.60.50.50.6-0.60.6-0.50.50.60.7-0.50.60.60.40.5-0.40.6-0.40.3-0.3-0.10.2
Context. condit. distance diff. score1.11.42.81.7-1.4-1.4-1.41.3-1.31.3-1.3-1.4-1.41.2-1.4-0.7-1.0-1.01.0-0.91.1-0.60.61.00.2
Locomotion velocity, session 10.20.21.20.10.0-0.00.0-0.1-0.30.3-0.3-0.60.0-0.00.10.40.40.4-0.40.60.3-1.01.00.21.1
Locomotion distance, session 10.40.63.10.30.30.30.5-0.20.2-0.20.2-0.00.4-0.60.60.50.80.9-0.71.60.8-0.70.71.11.8
Locomotion velocity, session 21.82.24.3-0.51.61.61.7-1.51.6-1.61.61.51.7-1.71.51.61.71.8-1.72.1-0.40.0-0.01.01.4
Locomotion distance, session 20.40.61.5-0.40.70.60.6-0.50.5-0.40.40.00.6-0.70.60.71.01.1-1.01.20.1-1.11.10.51.2
Locomotion velocity, session 31.21.45.82.3-1.1-1.1-0.81.3-0.90.8-0.8-0.8-0.90.5-0.7-0.5-0.5-0.20.50.82.3-0.50.52.41.9
Locomotion distance, session 30.10.21.80.7-0.2-0.2-0.10.3-0.20.1-0.1-0.2-0.10.1-0.0-0.00.00.10.00.20.5-0.50.51.30.4
Stereotopy head waving bouts, day 31.21.44.01.8-1.3-1.3-1.21.5-1.11.3-1.3-1.4-1.10.7-1.0-0.8-0.7-0.40.60.32.0-0.90.91.11.8
Stereotopy head waving duration, day 30.81.02.01.3-1.2-1.2-1.21.3-1.11.1-1.1-1.0-1.10.9-0.9-1.0-1.0-0.80.9-0.31.4-0.20.20.70.7
Locomotion velocity, session 70.80.93.21.8-1.0-1.1-0.91.1-0.80.9-0.9-0.8-1.00.7-1.0-0.7-0.8-0.50.80.41.6-0.10.11.01.1
Locomotion distance, session 70.30.31.30.7-0.4-0.4-0.40.5-0.40.5-0.5-0.8-0.30.1-0.4-0.10.20.2-0.10.30.6-1.11.10.81.0
Stereotopy head waving bouts, day 70.20.31.30.6-0.2-0.2-0.00.00.2-0.10.10.50.0-0.1-0.00.3-0.5-0.10.50.70.91.1-1.10.50.9
Stereotopy head waving duration, day 70.81.02.4-0.00.90.91.0-1.01.2-1.21.21.51.0-1.11.01.10.50.8-0.51.30.11.3-1.30.80.9
Locomotion velocity, session 81.01.22.4-1.51.21.11.1-1.30.9-0.50.50.11.0-1.10.71.51.51.5-1.41.1-0.5-0.90.9-1.31.2
Locomotion distance, session 80.40.62.80.9-0.7-0.8-0.50.6-0.60.9-0.9-0.9-0.60.3-0.60.0-0.4-0.10.40.81.7-0.30.30.61.6
Degree of sensitization distance0.20.21.70.9-0.3-0.4-0.30.4-0.20.3-0.3-0.4-0.30.0-0.50.0-0.00.1-0.00.50.8-0.40.40.31.3
Degree of sensitization stereotypy0.60.72.00.10.60.60.8-0.70.9-0.90.91.30.8-0.80.60.80.10.5-0.11.20.31.4-1.40.40.8
Conditioned locomotion1.11.32.4-1.11.31.31.3-1.31.3-1.11.10.91.4-1.31.21.51.41.4-1.31.1-0.6-0.40.4-0.10.9
Cocaine response after cond. corrected1.01.53.11.5-1.3-1.4-1.51.4-1.31.4-1.4-1.8-1.41.1-1.4-1.1-0.9-0.90.7-0.91.1-1.31.30.50.4
Cocaine response after cond. not corrected0.60.91.81.1-1.1-1.1-1.21.2-1.01.1-1.1-1.3-1.10.7-1.0-1.1-0.7-0.60.5-0.71.0-0.90.90.70.4
Cocaine response before conditioning0.91.02.4-1.21.11.11.2-0.81.0-1.31.31.51.1-0.91.30.30.70.7-0.60.7-0.81.3-1.30.2-0.4
Saline control response3.85.27.6-1.92.72.72.5-2.62.6-2.72.72.32.8-2.62.62.72.72.6-2.71.8-2.0-0.00.00.50.8
Bone: connectivity density1.93.06.5-1.31.81.82.0-1.52.0-1.81.82.02.1-2.22.11.41.82.1-1.72.60.00.7-0.70.22.0
Bone: cortical apparent density0.20.32.0-0.50.50.50.3-0.70.3-0.50.50.40.3-0.10.20.40.3-0.0-0.3-0.6-1.40.0-0.0-0.5-1.4
Bone: cortical area0.50.92.20.10.90.91.0-0.81.0-1.21.21.51.1-1.01.10.90.70.8-0.71.1-0.20.9-0.90.90.5
Bone: cortical porosity0.20.21.0-1.00.50.50.3-0.70.4-0.30.30.20.3-0.30.30.70.30.3-0.30.0-0.50.1-0.1-0.8-0.4
Bone: cortical porosity0.50.61.7-1.30.90.90.8-1.10.8-0.70.70.50.8-0.80.81.10.80.8-0.80.5-0.60.1-0.1-0.6-0.0
Bone: cortical thickness2.64.47.8-1.62.52.52.3-2.52.3-2.62.62.12.3-2.22.32.32.42.0-2.40.7-2.8-0.70.70.3-0.9
Bone: cortical thickness0.70.82.6-0.80.90.90.7-0.80.7-0.70.70.10.6-0.80.60.81.31.0-1.30.1-1.1-1.61.6-0.4-0.0
Bone: cortical tissue density0.30.52.3-0.70.60.70.5-0.90.5-0.70.70.50.4-0.30.40.60.50.2-0.5-0.6-1.5-0.00.0-0.6-1.4
Condit. Reinf. active minus inactive responses0.20.21.1-0.10.40.50.5-0.70.5-0.70.70.60.3-0.40.31.00.50.4-0.60.1-0.40.2-0.2-0.5-0.0
Condit. Reinf. active-inactive response ratio0.20.31.0-0.50.40.40.4-0.70.3-0.50.50.40.1-0.20.10.80.30.0-0.3-0.6-0.80.2-0.2-1.0-0.8
Condit. Reinf. active responses0.10.10.40.7-0.1-0.00.1-0.00.1-0.30.40.4-0.1-0.1-0.10.30.0-0.0-0.00.20.30.6-0.6-0.30.1
Condit. Reinf. inactive responses0.30.41.91.2-0.6-0.7-0.50.9-0.40.5-0.5-0.2-0.50.3-0.5-0.7-0.6-0.40.60.61.40.6-0.60.40.8
Incentive salience index mean0.30.31.10.10.50.50.6-0.60.6-0.80.80.70.5-0.70.51.10.70.6-0.70.6-0.00.1-0.10.10.5
Condit. Reinf. lever presses0.40.51.40.20.50.50.8-0.40.8-0.90.91.00.8-0.90.90.60.40.7-0.61.20.30.6-0.60.80.8
Condit. Reinf. active minus inactive responses0.20.32.10.2-0.4-0.4-0.30.2-0.30.2-0.20.2-0.30.3-0.2-0.3-0.7-0.60.80.00.71.4-1.40.0-0.1
Condit. Reinf. active-inactive response ratio0.91.54.40.9-1.3-1.3-0.91.1-0.91.0-0.9-0.3-1.00.9-0.9-1.1-1.5-1.21.6-0.02.12.1-2.1-0.60.4
Condit. Reinf. active responses0.10.20.7-0.00.20.20.4-0.40.3-0.40.50.70.3-0.20.30.5-0.00.00.10.3-0.10.8-0.80.4-0.1
Condit. Reinf. inactive responses0.71.02.6-0.71.11.11.0-1.10.8-1.01.00.61.0-0.80.81.41.21.0-1.10.3-1.6-1.01.00.8-0.2
Condit. Reinf. lever presses1.42.04.6-0.81.41.41.6-1.41.6-1.61.62.01.7-1.61.61.30.81.3-0.82.1-0.31.5-1.50.11.0
Condit. Reinf. lever reinforcers received0.30.41.1-0.30.60.60.7-0.70.6-0.80.81.00.7-0.50.70.70.20.3-0.20.6-0.41.0-1.00.4-0.1
Conditioned reinforcement - actives0.10.42.6-0.2-0.2-0.20.10.2-0.20.1-0.10.70.10.2-0.0-0.4-0.7-0.50.90.70.71.6-1.6-0.20.4
Conditioned reinforcement - inactives1.33.59.13.0-2.1-2.0-1.92.2-1.91.3-1.3-0.4-1.52.0-1.5-2.1-2.5-2.32.5-0.91.51.6-1.61.8-0.5
Conditioned locomotion6.79.918.74.3-3.7-3.7-3.53.7-3.63.1-3.1-2.4-3.33.7-3.5-3.6-3.8-3.83.8-2.42.20.2-0.21.5-1.4
Patch foraging indifference point 0 sec0.10.23.20.5-0.2-0.20.00.2-0.2-0.30.30.4-0.10.20.20.0-0.2-0.30.2-0.8-0.00.4-0.41.8-0.3
Patch foraging indifference point AUC1.43.25.7-1.72.02.02.4-2.02.0-2.12.12.42.0-1.71.61.71.61.5-1.41.7-1.32.0-2.0-0.30.0
Delay disc. indifference point, 0s delay0.50.64.20.3-0.3-0.4-0.10.3-0.20.8-0.8-1.0-0.4-0.1-0.3-0.00.30.4-0.10.71.3-1.11.10.12.0
Delay disc. indifference point, 16s delay0.60.83.61.9-0.9-0.9-0.91.0-0.80.4-0.4-0.2-0.80.8-0.9-0.7-0.9-0.91.1-0.60.70.4-0.41.6-0.3
Delay disc. indifference point, 2s delay0.20.21.20.6-0.3-0.3-0.20.3-0.00.5-0.5-0.4-0.2-0.0-0.5-0.3-0.10.10.10.51.10.1-0.1-0.61.0
Delay disc. indifference point, 24s delay0.10.20.80.40.10.1-0.10.1-0.1-0.20.1-0.1-0.00.0-0.10.30.30.1-0.2-0.4-0.8-0.90.90.6-0.4
Delay disc. indifference point, 4s delay0.40.42.00.60.10.1-0.1-0.20.2-0.0-0.0-0.5-0.1-0.4-0.10.70.60.6-0.60.40.2-1.41.41.30.9
Delay disc. indifference point, 8s delay0.20.31.4-0.60.20.1-0.2-0.20.20.3-0.4-0.70.1-0.30.00.40.50.6-0.50.10.2-1.21.2-0.60.9
Indifference point function ln k3.19.216.02.5-3.4-3.4-3.73.5-3.63.6-3.6-4.0-3.53.3-3.2-3.1-2.6-2.82.7-3.32.0-2.42.4-0.6-0.7
Indifference point function log k3.19.216.02.5-3.4-3.4-3.73.5-3.63.6-3.6-4.0-3.53.3-3.2-3.1-2.6-2.82.7-3.32.0-2.42.4-0.6-0.7
Patch foraging total patch changes 0 sec0.10.23.40.2-0.00.00.10.0-0.2-0.40.40.3-0.00.10.30.20.1-0.1-0.0-1.0-0.5-0.00.01.8-0.5
Patch foraging total patch changes 12 sec4.15.68.9-1.72.72.73.0-2.42.4-3.03.03.02.8-2.52.82.42.52.4-2.21.8-1.90.9-0.92.10.9
Patch foraging total patch changes 18 sec0.51.22.3-1.21.21.21.5-1.31.1-1.41.41.51.2-1.01.11.21.00.9-0.90.5-0.91.1-1.10.4-0.1
Patch foraging total patch changes 24 sec1.03.511.80.01.81.82.0-1.71.7-2.62.62.62.0-1.72.02.11.71.6-1.61.2-1.60.6-0.63.40.2
Patch foraging total patch changes 6 sec0.81.32.5-0.51.21.21.4-1.21.2-1.41.31.21.4-1.31.21.61.31.4-1.30.8-0.7-0.20.21.00.7
Patch foraging time to switch 0 sec0.41.66.7-0.41.11.11.2-1.01.5-1.01.01.31.4-1.61.31.21.01.5-1.12.60.70.5-0.50.42.2
Patch foraging water rate 0 sec1.24.612.61.9-2.3-2.2-2.52.2-2.51.9-1.9-1.9-2.42.7-2.4-2.1-2.2-2.72.1-3.6-0.0-0.40.4-0.3-2.6
Patch foraging water rate 12 sec2.49.718.53.5-3.4-3.3-3.93.3-3.73.1-3.1-3.5-3.53.7-3.5-2.9-3.0-3.42.8-4.30.7-2.02.01.1-2.3
Patch foraging water rate 18 sec1.63.66.32.5-2.1-2.0-2.52.2-2.21.8-1.9-2.2-1.92.0-2.1-1.8-1.6-1.71.5-2.20.6-1.81.80.9-0.9
Patch foraging water rate 24 sec2.73.98.41.8-2.1-2.1-2.62.1-2.22.0-2.1-2.2-2.22.2-2.3-2.1-1.9-2.11.7-2.90.6-1.01.00.0-1.5
Patch foraging water rate 6 sec3.45.011.22.5-2.4-2.3-2.62.4-2.62.1-2.1-2.7-2.62.6-2.6-2.1-1.7-2.31.6-3.40.3-1.91.90.6-1.9
Seeking ratio, delayed vs. immediate footshock0.20.32.01.4-0.6-0.5-0.60.4-0.40.2-0.2-0.3-0.70.4-0.6-0.2-0.5-0.50.3-0.50.0-0.30.30.4-0.4
Distance traveled before self-admin0.51.13.00.20.80.81.0-0.60.9-1.21.21.71.0-1.11.10.70.60.7-0.51.70.31.5-1.51.10.8
Distance traveled after self-admin0.20.41.0-0.50.60.70.4-0.60.5-0.80.91.00.6-0.40.70.50.30.2-0.30.3-0.90.7-0.70.8-0.5
Extensor digitorum longus weight6.124.334.2-3.45.55.55.8-5.45.7-5.75.75.35.7-5.85.65.85.45.7-5.45.3-2.50.4-0.42.13.3
Bone: elastic displacement0.81.03.30.7-0.7-0.7-1.00.7-1.00.8-0.9-1.4-1.11.1-1.1-0.6-0.3-0.80.4-1.8-0.6-1.61.6-0.0-1.2
Bone: elastic work1.11.42.9-0.11.21.21.0-1.11.0-1.21.10.51.1-1.11.01.41.61.3-1.60.3-1.4-1.71.71.20.2
Bone: endosteal estimation1.02.510.81.9-1.7-1.8-1.31.9-1.31.7-1.7-1.2-1.21.0-1.4-1.4-1.4-0.81.50.93.30.8-0.80.32.6
Bone: endosteal perimeter1.43.414.01.8-2.0-2.1-1.52.1-1.51.9-1.9-1.1-1.41.3-1.5-1.7-2.0-1.22.00.93.71.6-1.6-0.52.4
Epididymis fat weight1.99.823.44.8-3.7-3.7-3.33.7-3.22.8-2.8-1.9-3.33.2-3.1-3.4-3.7-3.43.7-1.63.51.5-1.53.20.3
Delta time in closed arm before/after self-admin0.70.73.60.60.20.20.10.20.1-0.40.4-0.5-0.2-0.30.40.11.10.6-0.9-0.2-0.5-1.91.91.70.2
Delta time in open arm before/after self-admin0.70.93.2-0.10.60.70.9-0.90.9-1.11.11.70.9-0.70.70.8-0.00.2-0.21.0-0.41.8-1.80.1-0.5
Diff in mean of infusions in LGA sessions0.40.81.8-0.21.01.00.7-0.90.9-1.41.41.10.7-0.90.81.11.10.8-0.90.4-1.0-0.10.11.3-0.0
Delay discount exponential model param0.10.20.6-0.3-0.2-0.2-0.00.2-0.30.1-0.10.1-0.20.40.0-0.5-0.5-0.50.4-0.4-0.20.7-0.7-0.3-0.8
Extinction: sum of active levers before priming1.62.55.6-0.61.71.71.8-1.61.8-1.91.91.91.6-1.71.61.71.61.7-1.62.4-0.40.4-0.40.91.8
Active lever presses in extinction session 63.23.25.7-1.52.02.02.2-1.92.0-2.12.12.42.0-2.01.91.71.61.7-1.52.4-0.71.6-1.60.10.7
Bone: final force1.83.06.3-0.61.81.72.0-1.62.0-1.91.92.02.0-2.12.01.71.72.0-1.62.5-0.20.7-0.71.41.8
Bone: final moment1.82.96.1-0.31.71.71.9-1.51.9-1.91.92.02.0-2.02.01.61.71.9-1.62.5-0.20.7-0.71.71.7
Food consumed during 24 hour testing period0.10.21.1-0.20.10.20.2-0.20.2-0.30.40.70.4-0.00.4-0.0-0.2-0.30.2-0.2-0.61.0-1.00.3-0.9
Glucose2.43.87.52.3-2.3-2.3-2.02.5-2.12.4-2.4-2.2-2.11.8-2.1-2.3-1.7-1.51.8-0.42.7-0.40.40.91.1
Heart weight1.01.74.91.6-1.1-1.2-1.11.4-1.11.3-1.3-1.7-0.90.6-0.8-0.9-0.3-0.10.30.22.2-1.41.42.12.2
Delay discount hyperbolic model param0.10.20.9-0.2-0.2-0.1-0.00.2-0.30.00.00.2-0.10.40.0-0.5-0.5-0.50.4-0.5-0.40.6-0.6-0.3-0.9
Intermittent access intake day 1-15 change0.31.53.90.6-1.2-1.2-1.31.1-1.21.1-1.0-0.4-0.91.4-0.9-1.3-1.6-1.61.6-1.00.52.0-2.0-0.5-1.2
Intermittent access intake escalation0.31.44.70.3-1.1-1.1-1.10.9-1.11.0-1.0-0.3-0.81.2-0.8-1.1-1.5-1.51.5-0.80.52.2-2.2-0.9-1.1
Intermittent access intake escalation 20.91.56.10.9-1.1-1.1-1.21.0-1.10.7-0.7-0.0-0.91.2-0.5-1.1-1.5-1.51.5-0.70.62.5-2.50.7-1.1
Intermitt. access day 1 inactive lever presses0.00.53.5-0.5-0.3-0.3-0.50.2-0.50.6-0.6-0.3-0.40.7-0.5-0.4-0.5-0.60.6-0.70.01.0-1.0-1.9-0.5
Intermitt. access day 15 inactive lever presses0.73.913.43.7-2.1-2.1-1.92.3-1.91.0-1.0-0.2-1.81.9-1.6-1.9-2.1-2.22.2-0.52.12.2-2.22.8-0.1
Intermitt. access escalation Index0.82.74.42.0-1.8-1.8-2.01.9-1.91.7-1.7-1.8-1.71.9-1.6-1.9-1.7-1.71.6-2.10.5-1.01.00.1-0.9
Intermittent access day 1 total infusions1.75.115.84.0-2.6-2.7-2.02.7-2.12.3-2.3-1.7-2.01.8-2.3-2.2-2.3-1.82.30.34.00.0-0.01.31.9
Intermittent access day 15 total infusions3.17.513.03.5-3.2-3.3-2.83.2-2.93.0-2.9-1.9-2.72.8-2.8-3.1-3.4-3.03.4-0.83.61.7-1.70.60.2
Intermittent access terminal intake (last 3 days)3.96.716.44.0-3.0-3.0-2.43.0-2.52.5-2.4-1.3-2.32.3-2.3-2.7-3.2-2.63.0-0.14.02.1-2.12.01.0
Intermittent access total infusions4.95.815.53.8-2.8-2.9-2.22.9-2.32.5-2.5-1.6-2.22.2-2.4-2.5-2.7-2.22.8-0.03.91.0-1.01.51.2
Intermittent access day 1 locomotion1.83.411.13.3-2.2-2.2-1.72.3-1.71.8-1.8-1.3-1.71.5-1.6-1.8-1.9-1.51.90.13.0-0.20.22.01.3
Intermittent access day 15 total locomotion1.56.014.13.8-2.8-2.8-2.32.9-2.42.1-2.1-1.0-2.22.3-2.2-2.6-3.1-2.73.1-0.43.31.9-1.92.40.2
Intermittent access total locomotion7.89.427.95.3-3.6-3.6-2.93.7-2.92.7-2.6-1.4-2.82.8-2.8-3.1-3.6-3.13.6-0.34.52.0-2.02.90.9
Intermittent access standard deviation0.31.72.71.6-1.5-1.5-1.61.5-1.31.2-1.2-0.7-1.31.4-1.0-1.4-1.7-1.61.6-0.71.31.3-1.30.8-0.7
Left kidney weight0.32.05.52.2-1.7-1.7-1.51.7-1.41.5-1.5-1.0-1.31.3-1.4-1.4-1.6-1.21.5-0.02.40.4-0.41.21.1
Right kidney weight0.21.22.71.7-1.3-1.3-1.11.5-1.11.1-1.0-0.6-0.91.0-0.9-1.4-1.3-1.11.2-0.31.60.5-0.51.30.5
Cocaine induced anxiety0.10.21.1-0.60.20.20.1-0.20.1-0.20.20.50.10.0-0.20.1-0.00.00.20.40.21.1-1.1-0.50.1
Post-drug Anxiety0.40.40.9-0.90.70.70.7-0.60.6-0.70.70.80.6-0.60.40.70.70.6-0.50.9-0.10.7-0.7-0.40.5
Baseline Anxiety0.30.41.6-0.10.50.50.5-0.40.5-0.60.60.10.6-0.60.70.50.80.7-0.80.0-0.9-1.31.30.30.2
Tail length0.42.15.3-1.51.71.71.4-1.81.4-1.61.61.01.2-1.31.11.81.91.4-1.80.2-2.3-0.90.9-1.0-0.9
Length with tail1.66.911.1-2.23.13.13.0-3.22.9-3.03.02.42.7-3.02.73.33.33.1-3.22.2-2.1-0.70.70.21.0
Length without tail1.15.58.4-0.82.62.62.7-2.42.5-2.92.92.32.6-2.62.62.62.82.7-2.72.0-1.6-0.80.82.41.4
Times rat made contact with spout0.70.82.0-1.31.01.00.7-1.10.7-0.80.80.50.9-0.70.71.21.10.8-1.00.0-1.4-0.60.6-1.1-0.5
Lifetime Intake3.54.311.93.2-2.4-2.5-1.92.5-2.02.2-2.2-1.6-2.01.8-2.2-2.2-2.3-1.82.3-0.13.40.1-0.11.31.4
Liver weight, left0.61.12.41.2-1.2-1.2-1.10.9-1.21.3-1.3-1.6-1.21.0-1.4-0.6-0.8-0.80.7-0.41.1-0.90.9-0.90.4
Liver weight, right1.73.06.12.2-1.9-1.9-2.01.9-2.02.0-2.1-2.5-1.81.7-2.0-1.3-1.0-1.11.2-0.91.6-2.02.00.90.8
Locomotor activity1.42.24.81.1-1.4-1.4-1.81.6-1.81.5-1.5-2.0-1.51.6-1.5-1.5-1.3-1.41.1-2.2-0.1-1.61.61.0-1.0
Locomotor testing distance1.22.95.31.5-1.6-1.6-1.91.7-2.01.6-1.7-2.3-1.91.8-1.8-1.5-1.2-1.41.0-2.20.1-2.32.31.5-1.0
Locomotor testing rearing0.72.76.21.5-1.6-1.6-2.01.7-2.01.6-1.6-2.1-1.91.7-1.6-1.4-1.0-1.41.1-2.00.6-1.71.72.5-0.8
Locomotion in novel chamber4.35.89.02.9-2.9-2.9-2.62.9-2.82.5-2.4-1.8-2.42.6-2.4-2.8-3.0-2.83.0-1.82.30.7-0.71.6-0.8
Locomotion in novel chamber post-restriction1.33.95.81.5-2.3-2.3-2.22.2-2.22.1-2.1-1.7-2.32.2-2.1-2.4-2.4-2.42.4-1.71.81.0-1.0-0.1-1.1
Fecal boli incidents, locomotor time 10.10.42.6-0.50.20.10.3-0.10.3-0.20.20.80.3-0.20.2-0.2-0.3-0.10.30.70.31.6-1.6-0.60.2
Change in fecal boli incidents, locomotor task0.50.52.2-0.3-0.2-0.3-0.60.2-0.40.9-0.9-1.4-0.20.3-0.60.00.20.2-0.2-0.40.3-1.51.5-1.50.4
Time >=10cm from walls, locomotor time 11.01.35.40.5-1.1-1.1-0.80.9-0.71.2-1.1-0.4-0.60.6-0.6-1.0-1.5-0.81.30.92.31.8-1.8-0.91.1
Bouts of movement, locomotor time 11.82.38.5-2.61.61.61.2-1.81.2-1.61.71.71.6-0.91.51.20.90.6-1.0-0.4-2.90.9-0.9-0.8-2.0
Total resting periods, locomotor time 11.41.66.2-2.11.21.31.0-1.31.0-1.41.41.61.4-0.61.40.70.50.3-0.6-0.4-2.51.1-1.10.0-1.9
Rest time, locomotor task time 11.01.62.90.5-1.4-1.3-1.11.1-1.51.4-1.4-1.1-1.31.6-1.6-1.2-1.7-1.61.4-1.60.20.4-0.4-0.7-1.7
Distance moved, locomotor task time 10.20.53.60.00.50.40.4-0.50.6-0.40.40.40.6-0.81.00.70.50.8-0.61.10.8-0.10.10.51.9
Vertical activity count, locomotor time 10.10.82.00.8-1.1-1.1-1.21.0-1.01.1-1.1-1.1-0.90.8-0.6-0.8-1.0-0.80.9-0.51.4-0.30.3-0.20.8
Time >=10cm from walls, locomotor time 20.10.42.9-0.80.20.20.1-0.50.2-0.20.30.80.3-0.00.30.3-0.4-0.30.40.30.11.7-1.7-0.4-0.7
Bouts of movement, locomotor time 20.20.61.5-0.10.70.80.9-0.60.7-1.21.21.10.6-0.60.80.50.60.4-0.60.1-1.10.1-0.11.2-0.4
Total resting periods, locomotor time 20.10.31.50.00.40.50.6-0.40.4-0.80.80.80.4-0.30.50.20.30.2-0.30.1-0.70.3-0.31.2-0.4
Rest time, locomotor task time 21.62.74.51.1-1.9-2.0-1.81.8-2.02.1-2.1-1.9-1.61.8-1.8-1.8-2.0-1.71.8-1.31.5-0.00.0-0.3-0.6
Distance moved, locomotor task time 21.21.63.1-1.81.51.51.3-1.61.4-1.41.41.31.3-1.31.61.51.31.2-1.30.7-1.30.3-0.3-0.30.2
Vertical activity count, locomotor time 20.10.21.0-0.60.20.3-0.1-0.2-0.0-0.10.1-0.3-0.10.0-0.00.20.30.1-0.3-0.7-0.9-0.90.9-1.0-0.6
Light reinforcement 10.00.21.2-0.3-0.2-0.2-0.30.1-0.4-0.00.00.0-0.10.40.00.0-0.2-0.50.3-0.9-0.40.4-0.40.4-1.1
Light reinforcement 21.02.34.62.1-1.6-1.6-1.51.8-1.51.0-1.0-0.2-1.31.5-1.1-1.8-1.8-1.82.0-0.41.62.1-2.11.3-0.5
Bone: marrow area1.12.611.02.0-1.8-1.9-1.41.9-1.41.8-1.8-1.3-1.31.1-1.5-1.4-1.5-0.91.50.83.30.6-0.60.22.6
Bone: maximum diameter0.30.63.40.10.20.20.5-0.10.5-0.50.51.10.6-0.50.70.1-0.10.20.21.11.01.8-1.80.31.0
Bone: maximum force2.24.412.7-0.21.91.82.3-1.62.3-2.22.22.62.4-2.52.31.71.72.3-1.73.60.71.5-1.51.92.9
Bone: maximum moment2.24.211.80.01.81.82.2-1.52.2-2.22.22.52.3-2.42.31.71.72.2-1.73.40.61.4-1.42.22.7
Mean time between licks in bursts0.10.84.0-0.10.70.80.5-0.60.5-0.50.5-0.20.6-0.50.50.81.31.0-1.20.0-1.2-2.02.00.70.3
Mean num. licks in bursts0.10.20.7-0.0-0.2-0.2-0.40.2-0.40.3-0.3-0.6-0.50.4-0.5-0.1-0.0-0.30.1-0.9-0.4-0.60.6-0.7-0.8
Cd content in liver1.01.12.30.4-1.1-1.1-0.90.8-0.81.1-1.0-0.4-1.11.0-1.1-0.8-1.5-1.31.4-0.71.31.5-1.5-0.6-0.4
Co content in liver1.11.36.6-0.2-0.7-0.6-1.00.3-1.00.9-0.9-1.4-1.11.1-1.1-0.2-0.4-1.00.3-2.6-1.1-1.71.7-0.4-1.9
Cu content in liver0.00.00.2-0.3-0.0-0.0-0.0-0.1-0.00.0-0.0-0.0-0.20.1-0.2-0.0-0.1-0.20.1-0.5-0.10.1-0.1-0.1-0.3
Fe content in liver0.30.31.2-0.90.50.40.4-0.60.6-0.20.20.20.3-0.60.30.80.50.6-0.51.10.40.1-0.1-1.00.9
K content in liver0.70.71.8-0.70.80.70.8-0.70.8-0.70.70.40.7-1.00.81.11.11.2-1.10.80.1-0.80.8-0.61.3
Mg content in liver0.30.31.20.8-0.5-0.5-0.50.4-0.50.4-0.4-0.7-0.60.3-0.40.1-0.1-0.10.0-0.40.6-1.11.10.50.6
Mn content in liver2.52.85.8-1.01.81.81.9-1.61.8-2.12.22.42.0-1.82.01.71.51.5-1.31.7-0.91.3-1.31.20.6
Na content in liver0.30.41.0-0.20.60.60.8-0.70.7-0.80.80.70.6-0.70.71.00.70.6-0.70.4-0.5-0.00.00.40.3
Rb content in liver1.82.14.71.0-1.6-1.6-1.61.2-1.51.9-1.9-2.2-1.91.4-1.8-1.0-1.2-1.31.0-1.31.1-1.31.3-1.0-0.1
Se content in liver0.30.42.30.7-0.5-0.4-0.30.4-0.20.1-0.10.5-0.40.3-0.4-0.4-0.8-0.70.80.10.71.5-1.50.1-0.3
Sr content in liver2.52.24.4-1.01.71.71.8-1.51.6-2.02.02.11.7-1.51.81.41.51.3-1.30.8-1.50.8-0.80.9-0.1
Zn content in liver0.50.51.30.00.70.80.9-0.70.8-1.11.11.00.6-0.70.70.80.90.6-0.80.2-0.6-0.10.11.10.1
Bone: minimum diameter1.12.07.52.3-1.6-1.7-1.21.8-1.21.3-1.3-0.8-1.11.0-1.1-1.3-1.4-0.91.40.62.70.9-0.91.41.8
Time in familiar zone, hab. session 10.30.31.71.3-0.6-0.5-0.50.5-0.40.3-0.3-0.3-0.50.4-0.5-0.2-0.4-0.40.5-0.40.4-0.40.41.30.2
Time in novel zone, hab. session 10.30.31.1-0.5-0.3-0.3-0.40.3-0.60.8-0.8-1.1-0.50.5-0.5-0.40.0-0.1-0.0-0.30.1-0.90.9-1.0-0.0
Total zone transitions, hab. session 10.40.51.7-0.90.70.70.7-1.00.6-0.70.70.70.8-0.71.01.30.60.7-0.60.9-0.20.2-0.20.00.5
Total locomotion distance, hab. session 10.40.62.01.1-1.0-1.0-0.90.7-0.90.9-0.9-0.7-0.80.6-0.5-0.2-0.8-0.60.80.31.4-0.10.10.41.0
Locomotion velocity, hab. session 10.10.10.60.6-0.4-0.4-0.30.2-0.40.3-0.3-0.2-0.30.2-0.00.3-0.4-0.20.30.40.80.0-0.00.30.8
Time in familiar zone, hab. session 20.50.63.1-1.00.50.50.1-0.40.3-0.10.0-0.60.2-0.40.20.60.80.6-0.8-0.6-1.0-1.81.8-1.0-0.3
Time in novel zone, hab. session 20.40.43.11.1-0.2-0.20.10.2-0.0-0.20.20.60.10.1-0.0-0.2-0.3-0.20.30.70.71.1-1.11.80.5
Total zone transitions, hab. session 20.91.13.3-0.30.90.91.1-0.80.8-0.90.90.81.1-1.21.31.31.11.4-1.11.80.3-0.50.51.11.8
Total locomotion distance, hab. session 20.30.42.40.7-0.4-0.4-0.20.3-0.40.4-0.4-0.5-0.30.0-0.00.30.00.20.00.71.1-0.80.80.81.5
Locomotion velocity, hab. session 20.30.42.30.9-0.6-0.7-0.40.6-0.60.6-0.6-0.6-0.40.3-0.20.0-0.3-0.10.40.61.4-0.50.50.61.5
Novel to familiar place preference ratio1.01.33.8-0.41.01.01.2-0.71.4-1.41.41.91.3-1.21.30.10.40.8-0.41.5-0.01.8-1.81.00.6
Novelty place preference0.70.83.2-0.20.70.70.8-0.31.0-1.01.01.60.9-0.90.9-0.30.10.4-0.11.00.11.8-1.80.90.4
Time in novel zone, NPP test0.60.72.30.00.60.60.7-0.20.9-0.91.01.40.8-0.80.9-0.30.10.4-0.21.00.21.5-1.51.20.5
Total zone transitions, NPP test1.62.34.7-1.51.71.61.7-1.71.6-1.51.51.41.8-1.82.01.81.61.8-1.62.2-0.20.2-0.20.61.4
Total locomotion distance, NPP test0.10.21.20.2-0.2-0.2-0.10.1-0.20.3-0.3-0.4-0.1-0.10.10.30.10.3-0.10.70.9-0.60.60.41.1
Locomotion velocity, NPP test0.10.10.6-0.0-0.1-0.1-0.0-0.0-0.10.2-0.2-0.3-0.0-0.10.10.40.00.2-0.00.60.6-0.40.4-0.10.8
Intraocular pressure0.81.23.80.2-0.8-0.8-0.90.8-0.80.4-0.40.2-0.81.1-0.9-1.4-1.6-1.71.3-1.5-0.31.7-1.7-0.2-2.0
Delta distance traveled before/after self-admin0.50.52.0-0.4-0.2-0.1-0.60.1-0.50.4-0.5-0.9-0.50.5-0.5-0.0-0.2-0.30.0-1.3-1.1-1.41.4-0.3-1.2
Delta ambulatory time before/after self-admin0.30.41.9-0.8-0.0-0.0-0.4-0.3-0.20.5-0.5-1.0-0.30.3-0.40.30.0-0.0-0.2-0.9-0.9-1.41.4-0.8-0.8
Parametrial fat weight3.07.011.83.2-3.1-3.2-2.73.4-2.92.9-2.9-2.2-2.52.7-2.5-3.1-2.9-2.63.1-1.13.40.7-0.72.90.7
Pavlov. Cond. lever latency0.30.41.4-0.5-0.5-0.5-0.70.4-0.70.9-0.9-0.8-0.70.8-0.7-0.6-0.5-0.60.6-0.90.2-0.10.1-1.2-0.5
Pavlov. Cond. magazine entry latency0.40.61.40.20.50.50.7-0.50.8-0.90.91.10.8-0.80.90.70.40.6-0.41.10.20.6-0.61.20.8
Pavlov. Cond. change in total contacts0.40.42.30.20.10.10.50.00.4-0.60.61.10.5-0.30.4-0.3-0.3-0.10.20.60.21.5-1.50.5-0.1
Pavlov. Cond. index score0.40.51.20.00.60.60.8-0.60.8-1.01.01.10.8-0.70.80.60.40.4-0.40.6-0.50.6-0.60.8-0.1
Pavlov. Cond. latency score0.20.30.70.30.50.50.6-0.50.6-0.80.80.80.6-0.60.70.60.40.4-0.40.6-0.30.4-0.40.80.1
Pavlov. Cond. lever contacts0.20.31.00.60.30.30.5-0.30.5-0.60.60.50.5-0.60.50.50.40.5-0.50.7-0.0-0.20.21.00.6
Pavlov. Cond. magazine entry number0.50.61.80.5-0.7-0.8-0.80.8-0.91.1-1.1-1.3-0.90.7-1.0-0.6-0.3-0.40.4-0.40.7-1.01.0-0.40.5
Pavlov. Cond. intertrial magazine entries0.70.83.40.8-0.7-0.7-0.80.7-0.70.4-0.3-0.1-0.91.0-1.0-1.1-1.0-1.31.0-1.4-0.30.9-0.9-0.5-1.8
Pavlov. Cond. lever-magazine prob. diff.0.50.71.6-0.10.80.81.0-0.81.0-1.11.11.31.0-0.91.00.80.50.6-0.60.9-0.50.7-0.70.80.1
Pavlov. Cond. response bias0.30.41.30.00.50.60.7-0.50.7-1.01.01.20.8-0.60.80.50.30.3-0.30.4-0.50.7-0.70.8-0.2
Pavlov. Cond. lever latency0.60.82.2-0.1-0.7-0.7-0.80.5-0.81.1-1.1-1.5-1.00.8-1.0-0.4-0.3-0.60.3-1.40.1-1.41.4-0.9-0.6
Pavlov. Cond. magazine entry latency3.34.78.2-1.42.52.52.5-2.12.4-2.82.82.92.6-2.42.72.02.12.3-2.02.4-1.30.9-0.91.21.1
Pavlov. Cond. change in total contacts0.92.36.0-0.01.21.21.5-1.11.5-1.71.82.41.5-1.41.60.90.50.9-0.52.1-0.12.4-2.42.00.8
Pavlov. Cond. index score1.93.07.0-0.61.71.71.9-1.41.9-2.22.22.62.1-1.92.11.21.21.5-1.12.3-0.51.8-1.81.41.1
Pavlov. Cond. latency score1.62.66.1-0.51.51.51.7-1.21.7-2.02.02.51.9-1.71.91.01.01.4-0.92.3-0.21.9-1.91.31.2
Pavlov. Cond. lever contacts0.60.82.2-0.20.80.80.9-0.60.9-1.11.11.51.1-0.91.10.40.30.6-0.31.3-0.31.4-1.40.80.5
Pavlov. Cond. magazine entry number5.67.213.91.6-3.0-3.0-3.22.7-3.13.4-3.4-3.7-3.23.0-3.2-2.5-2.4-2.62.3-3.11.5-1.71.7-1.7-1.2
Pavlov. Cond. intertrial magazine entries0.51.02.0-0.1-1.1-1.1-1.10.7-1.11.3-1.3-1.2-1.11.1-1.1-0.7-1.1-1.21.1-1.40.60.3-0.3-1.3-0.7
Pavlov. Cond. lever-magazine prob. diff.2.33.68.1-0.82.01.92.1-1.62.1-2.42.42.82.3-2.12.31.41.41.7-1.32.4-0.71.8-1.81.51.1
Pavlov. Cond. response bias1.82.55.5-0.61.61.61.8-1.31.7-2.02.02.42.0-1.71.91.21.21.5-1.12.1-0.71.4-1.41.51.0
Time in closed arm before self-admin0.30.51.50.9-0.6-0.6-0.50.7-0.60.5-0.50.1-0.30.6-0.6-0.7-0.9-0.71.10.61.01.2-1.20.70.3
Time in closed arm after self-admin0.60.71.30.7-0.8-0.8-1.01.1-1.00.9-1.0-1.1-0.90.8-0.8-0.9-0.5-0.60.7-0.50.5-0.70.70.90.0
Time in open arm before self-admin1.01.28.7-0.5-0.2-0.2-0.40.1-0.50.6-0.7-1.7-0.60.2-0.30.10.70.2-0.7-1.5-0.8-3.03.0-0.8-0.2
Time in open arm after self-admin0.40.51.2-0.50.70.70.7-1.00.7-0.70.70.40.7-0.50.41.00.60.6-0.9-0.3-1.1-0.70.7-0.7-0.4
Bone: periosteal estimation0.30.84.11.3-0.5-0.6-0.10.6-0.10.3-0.20.3-0.0-0.0-0.1-0.3-0.50.00.51.42.01.2-1.20.62.0
Bone: periosteal perimeter0.20.52.70.4-0.0-0.10.20.10.2-0.10.10.60.4-0.40.40.1-0.10.30.21.31.41.2-1.20.21.6
Bone: post-yield work1.11.910.30.9-0.2-0.30.50.40.40.0-0.00.90.5-0.70.5-0.2-0.40.50.52.92.92.2-2.20.73.2
Progressive ratio test 1 active lever presses0.40.62.00.9-0.9-0.9-0.60.9-0.71.0-1.0-0.5-0.60.7-1.1-0.8-1.0-0.60.90.41.4-0.10.1-0.30.9
Progressive ratio test 1 breakpoint0.30.61.90.8-0.8-0.8-0.60.8-0.60.9-0.9-0.4-0.50.6-1.0-0.8-1.0-0.60.80.51.40.0-0.0-0.31.0
Progressive ratio test 1 inactive lever presses0.10.33.41.3-0.3-0.3-0.30.5-0.3-0.10.20.50.30.20.2-0.4-0.6-0.30.50.20.1-0.00.01.80.7
Progressive ratio test 2 active lever presses2.53.57.42.7-2.2-2.2-1.72.2-1.81.8-1.8-0.9-1.81.9-2.1-2.1-2.4-2.12.4-0.52.41.3-1.31.00.1
Progressive ratio test 2 breakpoint2.83.57.82.8-2.2-2.2-1.72.2-1.91.8-1.8-0.9-1.82.0-2.1-2.1-2.4-2.12.4-0.52.31.4-1.41.10.1
Progressive ratio test 2 inactive lever presses3.19.722.04.7-3.7-3.6-3.43.7-3.32.7-2.6-1.6-3.03.4-3.1-3.5-4.0-3.73.9-2.02.91.6-1.62.5-0.8
Incentive Sensitization - Responses0.30.85.71.5-0.4-0.4-0.10.6-0.2-0.10.20.7-0.10.2-0.0-0.4-0.4-0.40.70.51.31.6-1.62.40.6
Incentive Sensitization - Breakpoint0.41.05.71.8-0.7-0.7-0.30.9-0.40.1-0.00.5-0.40.4-0.3-0.6-0.7-0.60.90.31.41.7-1.72.40.4
Sum of active levers in priming session hrs 5-61.71.66.9-1.31.11.11.0-1.11.0-1.41.42.11.1-0.60.90.50.10.1-0.20.6-1.22.6-2.6-0.4-1.3
Progressive ratio0.51.46.2-0.70.90.81.3-1.11.3-0.70.71.01.1-1.41.21.30.81.3-1.02.51.00.8-0.8-0.52.0
Food seeking constrained by brief footshock0.10.10.4-0.20.30.30.1-0.20.2-0.00.0-0.20.3-0.30.00.20.50.4-0.50.3-0.2-0.60.60.40.3
Seeking ratio, punishment vs. effort0.81.85.61.2-1.1-1.0-1.51.3-1.51.0-1.1-1.6-1.31.5-1.5-1.4-0.5-1.10.7-2.4-0.7-1.81.80.8-1.6
Retroperitoneal fat weight7.131.747.46.5-6.7-6.7-6.66.9-6.66.2-6.2-5.7-6.36.2-6.0-6.4-6.0-6.06.0-4.94.9-0.80.83.3-0.9
Reaction time number correct0.10.40.9-0.50.70.80.6-0.70.7-0.90.90.70.7-0.60.60.60.70.5-0.60.4-1.0-0.20.2-0.20.0
Reaction time mean minus median0.74.26.4-2.52.22.22.2-2.32.3-2.02.02.52.3-2.22.51.91.61.9-1.52.4-0.72.4-2.4-0.90.7
Reaction time mean minus median AUC0.42.56.0-2.41.81.71.7-1.91.7-1.51.61.81.7-1.72.01.61.11.4-1.31.5-1.01.5-1.5-1.3-0.1
Reaction time num false alarms0.61.05.4-0.1-0.4-0.4-0.70.6-0.80.7-0.8-1.5-0.90.7-0.7-0.60.1-0.3-0.0-1.5-0.7-2.32.3-1.1-0.6
Reaction time num false alarms AUC0.30.74.5-0.70.30.3-0.0-0.1-0.10.0-0.0-0.8-0.20.0-0.00.00.70.4-0.7-0.9-1.1-2.12.1-1.0-0.4
Reaction time trials correct on left0.10.40.9-0.50.70.80.6-0.70.7-0.90.90.70.7-0.60.60.60.70.5-0.60.4-1.0-0.20.2-0.20.0
Reaction time trials on left0.10.51.1-0.60.80.90.7-0.80.8-0.90.90.80.8-0.60.70.70.80.6-0.70.4-1.1-0.20.2-0.20.0
Reaction time mean0.10.31.9-0.40.10.10.2-0.30.1-0.20.20.60.2-0.20.40.1-0.3-0.10.30.60.31.4-1.4-0.6-0.0
Reaction time mean AUC0.10.32.2-0.40.10.00.1-0.20.1-0.10.10.60.2-0.10.40.1-0.4-0.20.40.50.41.5-1.5-0.50.1
Median of all reaction times0.20.30.70.6-0.5-0.5-0.40.4-0.50.4-0.30.1-0.30.4-0.2-0.4-0.8-0.60.80.10.70.8-0.8-0.20.0
Reaction time omissions0.91.43.9-2.01.51.41.3-1.31.2-1.21.21.41.4-1.21.61.00.91.2-0.91.1-1.20.5-0.50.00.4
Reaction time false alarm rate0.50.73.50.0-0.4-0.4-0.60.5-0.70.7-0.7-1.3-0.80.5-0.6-0.50.1-0.2-0.1-1.1-0.3-1.91.9-0.8-0.3
Reaction time premature initiation rate2.03.26.30.01.91.92.0-1.81.7-2.02.01.21.7-1.81.12.32.52.2-2.41.2-1.8-1.71.71.20.9
Reaction time premature initiations1.64.98.6-0.72.52.62.5-2.52.3-2.72.61.82.3-2.21.62.82.92.6-2.81.4-2.7-1.61.60.70.6
Std. dev. reaction times0.41.33.9-2.01.11.11.0-1.31.1-0.90.91.21.0-1.01.20.90.60.7-0.51.1-0.51.8-1.8-1.6-0.2
Reaction time trials completed0.10.51.1-0.60.80.90.7-0.80.8-0.90.90.80.8-0.60.70.70.80.6-0.70.4-1.1-0.20.2-0.20.0
Reaction time trials AUC0.10.30.8-0.40.60.70.5-0.60.6-0.80.80.60.6-0.50.60.60.60.5-0.60.3-0.9-0.30.3-0.00.1
Run reversals in cocaine runway, females0.70.73.60.70.30.20.40.10.3-0.20.2-0.30.4-0.60.60.50.91.0-0.80.50.4-1.91.91.51.4
Run reversals in cocaine runway, males0.20.21.6-0.3-0.2-0.2-0.2-0.2-0.20.5-0.5-0.6-0.20.2-0.40.5-0.5-0.20.1-0.50.0-0.50.5-1.3-0.0
Latency to leave start box in cocaine runway0.30.41.50.7-0.7-0.7-0.50.6-0.50.7-0.7-0.6-0.70.4-0.7-0.4-0.4-0.40.50.61.20.4-0.4-0.70.5
Latency to leave start box in cocaine runway, F0.00.10.20.5-0.3-0.3-0.10.2-0.00.1-0.1-0.1-0.40.1-0.1-0.1-0.1-0.20.10.40.40.2-0.2-0.1-0.0
Latency to leave start box in cocaine runway, M0.40.42.8-0.3-0.3-0.4-0.30.3-0.30.9-0.9-0.8-0.20.3-0.7-0.1-0.10.00.30.61.10.1-0.1-1.70.9
Std. dev. time between licks in bursts0.30.53.90.20.00.0-0.30.2-0.30.2-0.2-0.9-0.10.2-0.10.00.60.3-0.5-0.6-0.8-2.02.00.5-0.1
Total sessions with >9 infusions0.30.42.50.0-0.4-0.5-0.20.5-0.30.8-0.8-0.6-0.30.2-0.5-0.5-0.4-0.00.50.41.6-0.50.5-0.51.5
Short access day 1 total inactive lever presses1.83.58.83.0-2.2-2.2-2.32.2-2.11.8-1.7-1.7-2.02.0-1.9-2.0-1.9-2.01.9-1.51.8-0.60.61.20.1
Short access day 10 total inactive lever presses0.10.61.30.3-0.8-0.8-1.00.7-0.90.9-0.9-1.1-1.01.0-0.8-0.7-0.5-0.80.5-1.1-0.1-0.00.0-0.4-1.1
Short access day 1 total infusions1.32.65.01.8-1.9-1.9-1.61.8-1.72.0-2.0-1.8-1.71.6-1.9-1.8-1.6-1.41.6-0.82.2-0.80.8-0.70.9
Short access day 10 total infusions1.01.79.81.7-1.3-1.4-0.91.4-1.01.4-1.4-0.9-0.90.7-1.2-1.2-1.2-0.61.20.83.1-0.20.20.71.9
Short access total infusions1.21.77.41.4-1.3-1.3-0.91.4-1.01.5-1.5-1.3-1.00.7-1.2-1.2-1.0-0.51.00.52.7-1.01.00.52.1
Short access day 1 locomotion1.11.94.72.2-1.6-1.6-1.41.8-1.61.3-1.3-1.0-1.11.4-1.1-1.8-1.5-1.41.6-0.91.6-0.20.21.10.7
Short access day 10 total locomotion0.41.66.52.5-1.4-1.4-1.11.6-1.11.0-1.0-0.4-0.90.9-0.6-1.3-1.3-1.11.50.41.90.5-0.52.11.0
Short access total locomotion1.62.47.12.7-1.8-1.8-1.52.0-1.51.4-1.4-0.9-1.21.3-1.2-1.7-1.7-1.41.8-0.22.30.4-0.41.90.8
One hour access (0.3 mA shock)6.37.519.24.4-3.2-3.2-2.93.4-3.02.5-2.5-1.8-2.62.9-2.4-3.1-3.1-3.03.2-1.62.70.9-0.93.0-0.2
Compulsive drug intake1.92.98.1-1.91.92.01.7-2.01.6-1.81.70.81.3-1.51.51.92.41.7-2.1-0.1-2.9-1.41.4-0.5-0.6
One hour access (shock baseline)3.69.316.64.1-3.6-3.6-3.33.7-3.43.2-3.2-2.0-2.73.3-2.9-3.6-3.9-3.43.8-1.43.51.5-1.51.7-0.2
Social response proportion0.50.61.2-0.90.90.91.1-1.01.1-0.80.80.90.8-0.90.60.90.70.8-0.70.8-0.60.2-0.2-0.70.2
Social responses0.60.71.6-1.11.01.01.1-1.31.0-0.90.90.70.7-0.90.51.20.70.7-1.00.1-1.30.1-0.10.0-0.4
Social time0.30.52.1-1.40.90.90.7-1.00.7-0.60.60.40.6-0.80.70.90.80.8-0.90.1-0.8-0.10.1-0.3-0.1
Soleus weight3.410.014.33.0-3.7-3.7-3.83.4-3.73.7-3.7-3.7-3.83.7-3.7-3.1-3.4-3.53.3-3.32.0-0.80.8-0.2-1.5
Bone: stiffness1.52.76.4-1.41.61.61.9-1.61.9-1.61.62.12.0-1.91.91.51.21.7-1.22.50.31.6-1.6-0.31.9
Tibialis anterior weight8.529.141.1-4.56.26.26.4-6.26.4-6.46.46.26.3-6.26.36.35.65.8-5.75.0-3.61.2-1.21.52.2
Time to tail flick, vehicle, before self-admin0.30.42.70.30.20.20.60.00.5-0.30.30.50.4-0.60.30.00.50.6-0.21.41.20.4-0.40.21.6
Time to tail flick, vehicle, after self-admin0.81.65.7-0.61.21.11.1-1.01.1-0.80.80.61.3-1.51.21.51.51.8-1.52.00.6-0.50.51.12.4
Time to tail flick, test, before self-admin2.12.410.63.0-1.6-1.6-1.51.9-1.51.1-1.1-1.2-1.21.1-1.0-1.3-1.2-0.91.2-0.61.8-1.01.03.31.3
Time to tail flick, test, after self-admin0.30.31.4-0.80.50.50.5-0.50.6-0.50.50.80.5-0.60.60.10.20.4-0.20.7-0.01.2-1.20.30.2
Delta time to tail flick, vehicle, before/after SA0.70.71.6-0.90.90.90.8-1.00.8-0.70.70.30.9-1.00.81.31.11.2-1.30.7-0.4-0.60.60.20.8
Delta time to tail flick, test, before/after SA2.22.77.7-2.81.71.71.5-1.91.6-1.51.61.81.3-1.11.11.01.10.8-1.00.4-2.21.7-1.7-2.6-1.8
Tibia length1.02.88.3-0.21.41.41.8-1.41.8-2.12.12.91.7-1.51.51.00.70.9-0.71.9-0.42.9-2.90.7-0.0
Ambulatory time before self-admin0.31.03.4-0.10.70.70.9-0.50.7-1.11.21.71.0-0.91.20.50.30.5-0.21.50.31.9-1.91.30.6
Ambulatory time after self-admin0.20.31.50.6-0.5-0.4-0.50.4-0.40.1-0.10.2-0.30.4-0.1-0.5-0.8-0.70.70.20.31.0-1.01.2-0.5
Bone: tissue strength0.10.10.30.2-0.1-0.1-0.10.2-0.10.1-0.10.0-0.20.2-0.1-0.3-0.3-0.30.3-0.1-0.00.3-0.30.4-0.5
Total heroin consumption4.95.88.3-2.72.92.92.6-2.72.7-2.82.82.82.7-2.72.82.42.32.5-2.52.2-2.21.0-1.00.70.7
Bone: trabecular number0.61.24.1-0.00.80.81.1-0.51.1-1.11.11.51.2-1.21.20.40.71.0-0.62.00.71.3-1.30.81.7
Bone: trabecular spacing0.60.82.8-0.3-0.5-0.5-0.80.3-0.70.7-0.7-1.2-0.90.8-0.9-0.2-0.3-0.60.2-1.7-0.7-1.41.4-1.6-1.3
Bone: trabecular thickness0.50.71.41.2-0.9-0.9-0.81.0-0.80.8-0.8-0.6-0.80.7-0.6-1.1-0.8-0.70.9-0.11.20.5-0.51.00.5
Bone: trabecular tissue density2.64.66.60.6-2.2-2.2-2.42.0-2.42.6-2.6-2.4-2.52.5-2.3-2.4-2.5-2.52.4-2.40.7-0.00.0-2.0-1.8
Water consumed over 24 hours0.71.43.4-1.21.41.41.2-1.51.2-1.41.41.11.3-1.11.11.41.31.0-1.30.2-1.8-0.20.2-0.6-0.6
Number of responses in last shaping day0.20.32.00.40.00.1-0.10.2-0.3-0.20.2-0.00.10.2-0.1-0.30.1-0.00.1-0.6-0.8-1.31.31.4-0.2