Best TWAS P=1.344837e-07 · Best GWAS P=3.979479e-08 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Ankrd50 | mRNA stability | ENSRNOG00000010534 | 0.03 | 0.01 | blup | 1065 | 0.01 | 9.8e-03 | 5.0 | 5.3 | 1.3e-07 | 0.94 | 0.43 | 0.40 | TRUE |
| 2 | NAcc2 | NA | gene expression | ENSRNOG00000062674 | 0.06 | 0.04 | blup | 1059 | 0.04 | 2.4e-03 | 4.2 | -5.3 | 1.5e-07 | -0.96 | 0.38 | 0.45 | FALSE |
| 3 | OFC | Ankrd50 | gene expression | ENSRNOG00000010534 | 0.63 | 0.24 | lasso | 3 | 0.26 | 9.1e-07 | 4.3 | -5.2 | 2.5e-07 | -0.96 | 0.64 | 0.35 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.