Hub : Genes

Drap1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA alternative TSS NM_001077668.2 0.03 0.02 7.2e-03 0.01 0.01 0 0 4.4e-02 6.2e-02 1.6e-01 1.5e-01
2 pVTA alternative TSS XM_006230741.4 0.03 0.02 5.5e-03 0.01 0.01 0 0 4.2e-02 6.1e-02 2.2e-01 1.9e-01
3 Eye alternative TSS XM_006230741.4 0.49 0.22 8.7e-03 0.01 0.07 0.01 0.05 2.5e-01 2.7e-02 2.6e-01 5.7e-02
4 Eye alternative TSS NM_001077668.2 0.47 0.22 8.1e-03 0.01 0.07 0.01 0.05 2.5e-01 3.3e-02 2.2e-01 6.2e-02
5 RMTg gene expression Drap1 0.13 0.1 6.9e-03 0.1 0.02 0.01 0.03 1.5e-03 9.4e-02 1.4e-01 5.2e-02
6 Adipose gene expression Drap1 0.1 0.05 9.5e-08 0.04 0.04 0.04 0.04 9.6e-06 3.1e-05 2.0e-05 3.2e-05
7 Brain gene expression Drap1 0.18 0.09 2.1e-11 0.13 0.12 0.12 0.13 4.8e-12 4.3e-11 4.3e-11 8.0e-12
8 Liver alternative TSS XM_006230741.4 0.09 0.06 3.8e-06 0.03 0.04 0.04 0 5.1e-04 5.0e-05 4.9e-05 1.2e-01
9 PL gene expression Drap1 0.05 0.04 6.6e-04 0.03 0.03 0.02 0.02 6.5e-04 5.4e-04 3.3e-03 4.8e-03
10 Liver alternative TSS NM_001077668.2 0.08 0.05 1.0e-05 0.02 0.03 0.04 0 8.9e-04 1.0e-04 7.6e-05 9.8e-02
11 Liver gene expression Drap1 0.33 0.12 0.0e+00 0.13 0.16 0.17 0 2.4e-14 2.0e-17 1.0e-18 7.7e-02
12 pVTA gene expression Drap1 0.06 0.04 3.5e-04 0.01 0.04 0.03 0.03 2.1e-02 3.7e-04 2.3e-03 3.2e-03
13 NAcc gene expression Drap1 0.21 0.13 3.8e-14 0.06 0.1 0.1 0.1 1.5e-09 4.5e-15 4.5e-15 5.2e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density1.32.35.40.9-0.9-0.70.80.61.91.9-1.42.01.51.22.02.3
Area under the delay curve0.91.01.70.6-0.6-0.60.71.01.11.1-1.21.11.21.31.21.2
BMI with tail2.89.823.60.4-0.4-1.11.41.54.94.9-3.14.43.32.83.93.4
BMI without tail1.34.110.6-0.30.3-0.20.41.03.33.3-2.02.72.12.02.42.3
Body weight0.73.29.5-2.22.21.4-1.2-1.13.13.1-0.42.10.60.21.41.1
Weight adjusted by age0.71.02.2-1.51.51.2-1.2-1.3-0.1-0.11.0-0.4-1.0-1.2-0.7-0.7
Bone surface0.81.54.2-0.40.40.6-0.4-1.32.12.1-0.21.90.4-0.21.31.6
Bone volume0.81.43.90.4-0.4-0.40.6-0.31.81.8-0.92.01.00.51.61.6
Breakpoint value in progressive ratio session0.60.71.7-1.11.10.9-0.8-1.31.01.00.50.6-0.4-0.80.1-0.1
Number of licking bursts0.00.10.1-0.20.20.2-0.2-0.40.30.30.20.2-0.2-0.30.0-0.1
Context. condit. distance diff. score0.70.92.11.2-1.2-1.21.11.4-0.0-0.0-1.00.21.01.20.50.3
Locomotion velocity, session 10.30.30.7-0.80.80.8-0.8-0.2-0.2-0.20.5-0.7-0.5-0.2-0.6-0.5
Locomotion distance, session 11.01.33.30.0-0.0-0.00.20.61.81.8-1.11.41.11.11.31.5
Locomotion velocity, session 20.91.03.3-1.31.30.8-0.7-0.61.81.8-0.21.00.20.20.60.3
Locomotion distance, session 20.81.13.5-0.60.60.3-0.20.31.91.9-0.81.20.80.91.11.1
Locomotion velocity, session 30.91.11.60.6-0.6-0.80.81.31.21.2-1.11.01.21.31.10.9
Locomotion distance, session 30.00.00.10.0-0.0-0.10.10.30.20.2-0.10.00.00.20.10.1
Stereotopy head waving bouts, day 31.21.42.41.0-1.0-1.01.11.51.01.0-1.41.01.41.51.21.2
Stereotopy head waving duration, day 31.01.22.01.4-1.4-1.21.21.20.50.5-1.10.71.11.11.01.1
Locomotion velocity, session 72.52.74.10.9-0.9-1.51.51.81.81.8-2.01.82.02.01.81.2
Locomotion distance, session 70.60.81.5-0.10.1-0.20.30.91.21.2-1.00.91.01.20.90.8
Stereotopy head waving bouts, day 70.70.81.41.2-1.2-1.21.20.50.50.5-0.91.00.90.61.00.7
Stereotopy head waving duration, day 70.60.71.60.7-0.7-0.60.7-0.01.11.1-0.61.30.70.41.10.9
Locomotion velocity, session 80.91.12.6-1.41.41.6-1.5-1.10.00.01.1-0.7-1.1-0.9-0.8-0.2
Locomotion distance, session 80.71.01.80.6-0.6-0.90.91.11.11.1-1.21.01.21.31.00.5
Degree of sensitization distance0.60.71.10.2-0.2-0.30.40.61.01.0-1.01.01.00.91.01.0
Degree of sensitization stereotypy0.30.30.80.4-0.4-0.70.7-0.20.60.6-0.40.90.50.10.60.2
Conditioned locomotion0.80.92.8-1.71.71.3-1.2-1.10.30.30.6-0.2-0.6-0.7-0.5-0.6
Cocaine response after cond. corrected0.20.31.40.5-0.5-0.50.41.2-0.3-0.3-0.5-0.30.50.80.00.1
Cocaine response after cond. not corrected0.20.21.00.6-0.6-0.40.41.0-0.2-0.2-0.4-0.20.40.60.00.2
Cocaine response before conditioning0.10.10.7-0.10.10.2-0.2-0.80.20.20.40.2-0.4-0.6-0.0-0.0
Saline control response1.21.54.1-1.61.62.0-1.9-1.80.70.70.90.0-0.9-1.1-0.30.5
Bone: connectivity density1.11.74.90.0-0.00.2-0.0-0.22.02.0-0.81.90.90.61.72.2
Bone: cortical apparent density0.20.30.6-0.70.70.5-0.6-0.4-0.2-0.20.5-0.5-0.5-0.5-0.6-0.8
Bone: cortical area0.30.51.1-1.11.10.6-0.6-0.90.10.10.6-0.1-0.6-0.8-0.4-0.9
Bone: cortical porosity0.30.30.90.3-0.3-0.10.10.10.80.8-0.40.70.40.50.71.0
Bone: cortical porosity0.20.30.8-0.10.10.2-0.1-0.20.90.9-0.30.70.30.30.60.8
Bone: cortical thickness3.05.010.3-3.23.22.7-2.7-2.3-0.4-0.42.2-1.4-2.2-2.1-1.9-2.0
Bone: cortical thickness1.51.83.7-1.91.91.8-1.8-1.0-0.5-0.51.3-1.1-1.3-1.0-1.2-0.9
Bone: cortical tissue density0.30.50.8-0.90.90.7-0.8-0.6-0.3-0.30.7-0.5-0.6-0.7-0.7-0.8
Condit. Reinf. active minus inactive responses0.20.30.7-0.30.3-0.00.10.20.80.8-0.50.60.60.50.50.4
Condit. Reinf. active-inactive response ratio0.00.00.1-0.10.1-0.00.00.10.30.3-0.30.20.30.20.20.2
Condit. Reinf. active responses0.40.50.9-0.30.3-0.40.40.51.01.0-0.90.90.90.70.70.2
Condit. Reinf. inactive responses0.50.60.90.1-0.1-0.80.80.80.90.9-1.00.91.00.90.80.1
Incentive salience index mean0.60.82.1-0.30.3-0.20.30.51.41.4-0.91.11.00.91.00.6
Condit. Reinf. lever presses0.30.41.3-0.60.6-0.20.2-0.01.11.1-0.60.90.60.40.6-0.1
Condit. Reinf. active minus inactive responses0.30.41.51.2-1.2-0.80.80.10.00.0-0.30.50.30.10.50.7
Condit. Reinf. active-inactive response ratio0.80.92.41.5-1.5-1.61.50.7-0.0-0.0-0.80.60.70.50.60.2
Condit. Reinf. active responses0.40.62.01.1-1.1-0.50.60.00.60.6-0.50.90.50.20.91.4
Condit. Reinf. inactive responses0.40.53.00.3-0.30.4-0.2-0.10.90.9-0.30.80.30.30.91.7
Condit. Reinf. lever presses0.20.31.5-0.40.40.4-0.3-1.20.70.70.30.8-0.2-0.70.40.4
Condit. Reinf. lever reinforcers received0.30.41.50.9-0.9-0.20.3-0.30.50.5-0.20.80.2-0.10.71.2
Conditioned reinforcement - actives0.30.51.00.1-0.1-0.1-0.0-0.9-1.0-1.00.7-0.6-0.7-1.0-0.7-0.9
Conditioned reinforcement - inactives0.81.22.71.6-1.6-1.61.50.9-1.6-1.6-0.2-0.50.20.0-0.1-0.3
Conditioned locomotion1.82.44.72.1-2.1-2.11.91.6-2.2-2.2-0.5-0.90.40.5-0.3-0.5
Patch foraging indifference point 0 sec0.10.20.50.7-0.7-0.40.40.30.20.2-0.40.30.40.20.40.6
Patch foraging indifference point AUC0.71.13.3-1.31.31.1-1.1-1.80.10.11.0-0.2-1.0-1.4-0.6-0.8
Delay disc. indifference point, 0s delay1.61.83.80.8-0.8-1.01.01.41.41.4-1.61.31.62.01.41.3
Delay disc. indifference point, 16s delay1.11.32.01.3-1.3-1.41.41.40.70.7-1.10.91.11.11.00.7
Delay disc. indifference point, 2s delay0.40.40.60.7-0.7-0.70.70.70.40.4-0.80.60.70.80.70.6
Delay disc. indifference point, 24s delay0.10.10.2-0.40.40.5-0.50.1-0.1-0.10.2-0.4-0.20.1-0.3-0.1
Delay disc. indifference point, 4s delay0.70.71.50.3-0.3-0.30.41.00.80.8-1.00.81.01.20.91.2
Delay disc. indifference point, 8s delay0.40.41.00.3-0.3-0.20.30.70.60.6-0.80.60.70.90.71.0
Indifference point function ln k1.32.38.61.7-1.7-1.81.72.9-0.9-0.9-1.4-0.41.31.90.30.2
Indifference point function log k1.32.38.61.7-1.7-1.81.72.9-0.9-0.9-1.4-0.41.31.90.30.2
Patch foraging total patch changes 0 sec0.00.00.10.1-0.10.2-0.2-0.1-0.1-0.10.1-0.2-0.1-0.2-0.20.1
Patch foraging total patch changes 12 sec0.91.12.6-1.21.21.3-1.2-1.61.41.40.40.8-0.3-0.70.30.4
Patch foraging total patch changes 18 sec0.10.20.5-0.10.10.1-0.0-0.40.70.7-0.20.70.3-0.00.50.5
Patch foraging total patch changes 24 sec0.91.63.8-1.41.41.7-1.7-1.9-0.1-0.11.3-0.6-1.3-1.5-0.9-0.5
Patch foraging total patch changes 6 sec0.20.40.8-0.60.60.9-0.8-0.60.90.90.20.4-0.1-0.20.30.7
Patch foraging time to switch 0 sec1.22.56.20.1-0.1-0.60.80.42.52.5-1.52.51.61.22.11.7
Patch foraging water rate 0 sec1.32.78.40.5-0.5-0.2-0.10.2-2.9-2.91.1-2.5-1.2-0.9-2.0-1.8
Patch foraging water rate 12 sec1.53.211.41.0-1.0-0.30.11.3-3.4-3.40.9-2.9-1.0-0.3-1.9-1.2
Patch foraging water rate 18 sec0.50.72.30.5-0.5-0.20.11.0-1.5-1.50.2-1.4-0.30.2-0.8-0.5
Patch foraging water rate 24 sec1.11.64.90.5-0.5-0.30.20.9-2.2-2.20.6-2.0-0.7-0.2-1.5-1.4
Patch foraging water rate 6 sec1.31.95.8-0.10.10.3-0.40.7-2.4-2.40.9-2.4-1.0-0.4-1.8-1.3
Seeking ratio, delayed vs. immediate footshock0.81.01.40.6-0.6-0.90.91.11.01.0-1.21.11.21.11.21.1
Distance traveled before self-admin0.30.41.00.4-0.4-0.40.5-0.20.90.9-0.51.00.50.20.80.4
Distance traveled after self-admin0.00.00.20.1-0.10.1-0.1-0.40.10.10.20.1-0.2-0.40.0-0.0
Extensor digitorum longus weight2.18.123.3-4.84.83.5-3.3-3.32.72.71.51.0-1.3-1.7-0.3-1.0
Bone: elastic displacement1.51.83.8-1.01.01.0-1.1-0.3-1.7-1.71.2-1.9-1.3-0.9-1.7-1.5
Bone: elastic work1.62.14.8-2.22.21.9-1.9-1.2-0.2-0.21.3-1.1-1.3-1.0-1.3-1.2
Bone: endosteal estimation1.73.85.02.1-2.1-2.22.22.01.21.2-2.21.82.22.02.01.7
Bone: endosteal perimeter2.24.77.82.8-2.8-2.72.72.01.01.0-2.21.92.22.02.11.9
Epididymis fat weight1.13.910.13.2-3.2-3.02.82.2-1.4-1.4-1.4-0.11.31.30.4-0.1
Delta time in closed arm before/after self-admin0.40.41.3-1.11.11.1-1.1-0.10.30.30.3-0.3-0.30.0-0.30.2
Delta time in open arm before/after self-admin0.20.20.50.2-0.2-0.30.2-0.7-0.3-0.30.4-0.0-0.4-0.7-0.2-0.5
Diff in mean of infusions in LGA sessions0.30.40.6-0.70.70.8-0.8-0.8-0.1-0.10.7-0.3-0.7-0.8-0.5-0.3
Delay discount exponential model param0.60.71.2-0.40.40.4-0.5-0.8-1.0-1.00.9-0.9-0.9-1.1-1.0-1.0
Extinction: sum of active levers before priming0.70.82.8-0.50.50.2-0.1-0.41.71.7-0.41.30.50.20.90.6
Active lever presses in extinction session 60.90.92.9-1.11.11.0-1.0-1.70.30.31.0-0.0-0.9-1.3-0.5-0.8
Bone: final force0.50.82.0-1.41.41.0-1.0-1.30.90.90.50.5-0.4-0.70.0-0.1
Bone: final moment0.50.71.8-1.41.41.0-1.0-1.20.90.90.40.5-0.4-0.70.0-0.1
Food consumed during 24 hour testing period0.60.91.5-0.10.10.4-0.5-1.0-1.2-1.21.1-1.0-1.1-1.2-1.0-1.0
Glucose3.25.08.22.4-2.4-2.42.52.91.11.1-2.51.72.52.62.12.2
Heart weight3.24.97.71.9-1.9-1.71.82.71.91.9-2.51.92.52.82.32.6
Delay discount hyperbolic model param0.70.71.2-0.50.50.5-0.6-0.8-0.9-0.91.0-1.0-1.0-1.1-1.0-1.0
Intermittent access intake day 1-15 change0.30.61.90.8-0.8-0.80.70.2-1.4-1.40.2-0.8-0.3-0.3-0.6-0.9
Intermittent access intake escalation0.30.72.10.6-0.6-0.70.6-0.1-1.5-1.50.4-0.9-0.4-0.5-0.7-1.1
Intermittent access intake escalation 20.60.61.80.7-0.7-0.80.6-0.1-1.3-1.30.3-0.8-0.4-0.5-0.7-1.1
Intermitt. access day 1 inactive lever presses0.00.10.20.3-0.3-0.40.30.3-0.3-0.3-0.0-0.10.0-0.0-0.1-0.3
Intermitt. access day 15 inactive lever presses0.51.13.11.4-1.4-1.81.71.2-0.6-0.6-0.80.30.80.70.60.2
Intermitt. access escalation Index1.31.93.91.7-1.7-1.71.62.0-0.2-0.2-1.50.51.41.70.90.9
Intermittent access day 1 total infusions3.75.98.42.8-2.8-2.82.92.70.80.8-2.72.02.72.52.42.3
Intermittent access day 15 total infusions2.03.07.02.6-2.6-2.62.51.9-1.1-1.1-1.40.31.31.20.80.6
Intermittent access terminal intake (last 3 days)2.73.57.82.8-2.8-2.82.72.0-0.7-0.7-1.70.81.61.41.20.9
Intermittent access total infusions3.23.86.82.5-2.5-2.62.62.2-0.1-0.1-2.01.21.91.81.71.5
Intermittent access day 1 locomotion2.73.45.12.1-2.1-2.22.32.20.50.5-2.01.52.01.91.81.7
Intermittent access day 15 total locomotion1.83.27.72.6-2.6-2.82.71.9-0.8-0.8-1.60.71.51.21.10.7
Intermittent access total locomotion5.36.313.43.3-3.3-3.73.62.9-0.3-0.3-2.51.52.42.22.01.4
Intermittent access standard deviation0.20.51.80.7-0.7-0.70.60.3-1.3-1.30.1-0.7-0.2-0.1-0.5-0.5
Left kidney weight0.42.14.41.6-1.6-2.12.01.80.10.1-1.80.81.71.71.00.0
Right kidney weight0.10.40.80.7-0.7-0.90.80.6-0.7-0.7-0.3-0.40.20.4-0.3-0.8
Cocaine induced anxiety0.00.00.00.0-0.0-0.20.2-0.10.00.00.10.1-0.1-0.10.0-0.2
Post-drug Anxiety0.20.20.5-0.40.40.4-0.4-0.70.30.30.50.0-0.5-0.6-0.2-0.3
Baseline Anxiety0.30.41.0-0.60.61.0-0.9-0.8-0.0-0.00.7-0.5-0.7-0.6-0.6-0.2
Tail length0.83.05.6-2.42.42.2-2.2-1.8-0.6-0.61.7-1.4-1.7-1.5-1.6-1.4
Length with tail1.35.511.8-3.43.43.1-3.1-2.80.00.02.2-1.1-2.2-2.2-1.7-1.5
Length without tail1.54.89.2-3.03.03.0-3.0-2.6-0.1-0.12.3-1.2-2.2-2.2-1.7-1.2
Times rat made contact with spout0.20.20.6-0.40.40.5-0.4-0.20.80.8-0.10.40.10.20.30.7
Lifetime Intake2.43.04.82.1-2.1-2.22.22.00.10.1-1.81.21.81.71.61.5
Liver weight, left0.10.20.6-0.00.0-0.20.10.7-0.8-0.8-0.2-0.70.10.3-0.4-0.5
Liver weight, right0.30.52.00.5-0.5-0.40.41.4-0.9-0.9-0.5-0.60.50.9-0.10.2
Locomotor activity0.60.92.9-0.20.20.4-0.50.5-1.7-1.70.7-1.7-0.7-0.2-1.2-0.7
Locomotor testing distance0.61.13.7-0.20.20.5-0.60.6-1.8-1.80.7-1.9-0.8-0.2-1.3-0.6
Locomotor testing rearing0.30.72.20.8-0.80.0-0.00.9-1.5-1.50.1-1.2-0.20.3-0.50.7
Locomotion in novel chamber1.51.94.42.1-2.1-2.01.91.6-1.2-1.2-0.9-0.20.81.00.30.1
Locomotion in novel chamber post-restriction0.91.43.31.8-1.8-1.81.71.4-0.8-0.8-0.9-0.00.80.90.40.1
Fecal boli incidents, locomotor time 10.10.20.50.5-0.5-0.70.6-0.3-0.1-0.10.00.1-0.0-0.3-0.1-0.7
Change in fecal boli incidents, locomotor task0.30.30.9-0.10.10.3-0.20.60.70.7-0.40.30.40.60.50.9
Time >=10cm from walls, locomotor time 12.72.95.11.9-1.9-2.32.31.51.01.0-1.81.71.81.51.81.2
Bouts of movement, locomotor time 10.60.72.0-0.80.80.9-0.9-1.40.00.01.0-0.3-1.0-1.2-0.6-0.6
Total resting periods, locomotor time 10.30.31.3-0.40.40.5-0.5-1.10.10.10.7-0.0-0.6-0.9-0.3-0.4
Rest time, locomotor task time 10.40.51.10.9-0.9-0.80.70.4-1.0-1.00.1-0.7-0.10.0-0.5-0.6
Distance moved, locomotor task time 10.60.91.60.3-0.3-0.40.50.61.21.2-1.11.31.11.01.21.3
Vertical activity count, locomotor time 10.10.21.00.5-0.5-0.60.61.0-0.3-0.3-0.5-0.00.40.50.20.3
Time >=10cm from walls, locomotor time 20.10.10.30.3-0.3-0.50.5-0.20.10.1-0.20.40.2-0.00.2-0.3
Bouts of movement, locomotor time 20.10.10.4-0.20.20.2-0.2-0.40.60.60.10.3-0.1-0.20.20.2
Total resting periods, locomotor time 20.10.10.60.1-0.1-0.10.2-0.00.70.7-0.20.50.20.10.40.4
Rest time, locomotor task time 20.70.92.11.3-1.3-1.41.31.5-0.3-0.3-0.80.00.71.00.30.0
Distance moved, locomotor task time 20.60.71.5-1.21.21.2-1.1-1.20.00.00.8-0.3-0.7-0.8-0.5-0.4
Vertical activity count, locomotor time 21.41.92.7-1.31.31.4-1.5-0.9-1.3-1.31.5-1.6-1.5-1.2-1.6-1.3
Light reinforcement 10.00.10.40.2-0.20.2-0.2-0.1-0.6-0.60.3-0.5-0.3-0.3-0.30.0
Light reinforcement 20.30.51.11.0-1.0-1.11.00.3-0.9-0.9-0.0-0.3-0.0-0.2-0.2-0.6
Bone: marrow area1.94.25.32.2-2.2-2.32.32.11.31.3-2.31.92.32.22.11.8
Bone: maximum diameter0.10.10.50.2-0.2-0.20.1-0.7-0.2-0.20.40.0-0.4-0.6-0.2-0.6
Bone: maximum force0.61.13.8-0.80.80.4-0.3-0.81.91.9-0.41.70.50.01.10.7
Bone: maximum moment0.61.03.5-0.80.80.4-0.3-0.71.91.9-0.41.60.50.01.00.7
Mean time between licks in bursts0.20.61.8-1.01.01.3-1.3-0.50.00.00.8-0.6-0.8-0.5-0.60.1
Mean num. licks in bursts0.10.10.40.3-0.3-0.10.10.50.00.0-0.40.10.40.50.30.7
Cd content in liver0.70.82.31.5-1.5-1.31.30.6-0.7-0.7-0.60.10.50.30.30.1
Co content in liver1.11.33.2-0.70.70.7-0.8-0.1-1.6-1.60.9-1.8-1.0-0.6-1.5-1.4
Cu content in liver0.50.60.80.4-0.4-0.60.70.80.90.9-0.90.90.90.90.90.6
Fe content in liver0.40.50.7-0.60.60.8-0.8-0.7-0.5-0.50.8-0.7-0.8-0.8-0.7-0.5
K content in liver0.50.51.5-0.30.30.1-0.00.21.21.2-0.60.90.70.60.70.7
Mg content in liver0.60.61.10.7-0.7-0.60.61.00.70.7-0.90.60.91.10.80.9
Mn content in liver0.70.82.7-1.11.11.1-1.0-1.60.40.40.90.2-0.8-1.2-0.3-0.4
Na content in liver1.01.11.6-0.90.90.9-1.0-1.2-0.7-0.71.2-1.0-1.2-1.2-1.2-1.3
Rb content in liver0.91.02.31.3-1.3-1.01.01.50.10.1-1.00.31.01.20.81.3
Se content in liver0.20.20.70.8-0.8-0.70.70.1-0.3-0.3-0.20.20.2-0.00.20.2
Sr content in liver2.01.73.3-1.41.41.5-1.5-1.8-0.4-0.41.5-0.8-1.4-1.5-1.1-1.1
Zn content in liver0.10.20.5-0.50.50.2-0.2-0.00.70.7-0.30.40.30.30.30.2
Bone: minimum diameter2.95.36.82.2-2.2-2.42.52.31.71.7-2.62.32.62.42.52.2
Time in familiar zone, hab. session 10.60.60.80.8-0.8-0.80.80.80.50.5-0.90.70.90.90.70.6
Time in novel zone, hab. session 10.60.61.4-0.40.40.8-0.8-0.3-1.0-1.00.9-1.2-1.0-0.6-1.0-0.4
Total zone transitions, hab. session 10.30.41.1-0.80.80.2-0.2-0.21.11.1-0.30.70.30.20.50.1
Total locomotion distance, hab. session 10.71.01.60.6-0.6-1.11.11.20.90.9-1.30.91.31.20.90.3
Locomotion velocity, hab. session 10.40.61.10.2-0.2-0.70.70.81.01.0-1.00.91.00.90.80.2
Time in familiar zone, hab. session 20.50.51.1-0.80.81.0-1.0-0.3-0.6-0.60.8-0.9-0.8-0.5-0.8-0.3
Time in novel zone, hab. session 20.60.61.00.6-0.6-0.70.70.40.90.9-0.81.00.80.60.90.8
Total zone transitions, hab. session 22.43.07.10.6-0.6-0.30.60.72.62.6-1.52.31.61.42.22.7
Total locomotion distance, hab. session 22.12.84.11.0-1.0-1.01.11.52.02.0-1.81.91.91.91.91.9
Locomotion velocity, hab. session 22.33.03.91.3-1.3-1.31.41.71.91.9-1.91.92.01.92.01.8
Novel to familiar place preference ratio0.20.20.70.4-0.4-0.40.4-0.70.50.5-0.10.80.2-0.30.50.2
Novelty place preference0.20.30.60.7-0.7-0.60.6-0.30.50.5-0.30.80.3-0.10.50.3
Time in novel zone, NPP test0.20.20.50.7-0.7-0.50.5-0.30.40.4-0.30.70.3-0.10.50.4
Total zone transitions, NPP test0.70.93.1-0.80.80.6-0.4-0.51.81.8-0.41.30.50.30.90.9
Total locomotion distance, NPP test0.71.02.1-0.00.0-0.40.50.81.51.5-1.21.21.21.11.10.7
Locomotion velocity, NPP test0.60.92.1-0.10.1-0.50.50.71.41.4-1.11.21.11.01.00.6
Intraocular pressure0.81.23.70.7-0.7-0.60.5-0.4-1.9-1.90.7-1.2-0.8-1.0-1.1-1.3
Delta distance traveled before/after self-admin0.40.40.9-0.30.30.7-0.7-0.1-0.7-0.70.7-1.0-0.7-0.5-0.8-0.3
Delta ambulatory time before/after self-admin0.40.50.9-0.40.40.8-0.9-0.2-0.6-0.60.8-0.9-0.8-0.6-0.8-0.3
Parametrial fat weight2.04.810.22.9-2.9-3.23.12.7-0.2-0.2-2.21.02.22.21.50.8
Pavlov. Cond. lever latency0.20.20.70.3-0.30.1-0.10.0-0.9-0.90.4-0.7-0.5-0.3-0.5-0.2
Pavlov. Cond. magazine entry latency0.91.22.30.5-0.5-0.90.90.51.51.5-1.11.51.21.01.30.9
Pavlov. Cond. change in total contacts0.60.61.20.5-0.5-1.11.00.30.90.9-0.81.10.80.50.90.0
Pavlov. Cond. index score0.10.10.3-0.10.1-0.30.3-0.20.50.5-0.20.50.20.10.3-0.1
Pavlov. Cond. latency score0.20.20.50.1-0.1-0.40.40.10.70.7-0.50.70.50.30.50.2
Pavlov. Cond. lever contacts0.30.30.8-0.00.0-0.30.30.30.90.9-0.60.80.60.60.70.3
Pavlov. Cond. magazine entry number0.10.10.20.2-0.20.1-0.10.5-0.2-0.2-0.2-0.30.10.3-0.00.5
Pavlov. Cond. intertrial magazine entries0.20.20.90.1-0.1-0.30.2-0.0-1.0-1.00.2-0.6-0.2-0.3-0.5-0.6
Pavlov. Cond. lever-magazine prob. diff.0.20.20.8-0.10.1-0.40.4-0.10.90.9-0.40.80.40.20.5-0.0
Pavlov. Cond. response bias0.00.10.2-0.30.3-0.10.1-0.30.30.30.00.30.0-0.20.1-0.4
Pavlov. Cond. lever latency0.20.20.80.6-0.6-0.30.30.90.10.1-0.5-0.00.50.70.20.6
Pavlov. Cond. magazine entry latency0.81.02.8-1.11.10.8-0.7-1.11.71.70.11.30.0-0.30.80.7
Pavlov. Cond. change in total contacts0.20.41.40.0-0.0-0.30.4-0.81.01.0-0.11.20.2-0.30.70.2
Pavlov. Cond. index score0.40.51.2-0.70.70.3-0.2-1.01.11.10.11.0-0.0-0.50.50.1
Pavlov. Cond. latency score0.30.41.0-0.80.80.2-0.2-0.91.01.00.01.00.0-0.40.5-0.0
Pavlov. Cond. lever contacts0.10.20.8-0.40.40.2-0.2-0.9-0.0-0.00.50.1-0.5-0.7-0.1-0.4
Pavlov. Cond. magazine entry number1.11.43.31.4-1.4-1.21.01.8-1.6-1.6-0.5-1.20.40.9-0.5-0.4
Pavlov. Cond. intertrial magazine entries0.30.41.01.0-1.0-0.80.70.6-0.8-0.8-0.2-0.40.10.2-0.1-0.1
Pavlov. Cond. lever-magazine prob. diff.0.40.61.4-0.80.80.4-0.3-1.11.21.20.21.1-0.1-0.50.50.2
Pavlov. Cond. response bias0.30.41.1-0.60.60.4-0.3-1.10.90.90.30.8-0.2-0.50.40.2
Time in closed arm before self-admin0.50.61.41.2-1.2-1.21.20.60.10.1-0.70.70.70.50.70.5
Time in closed arm after self-admin0.10.10.50.1-0.1-0.30.30.70.10.1-0.40.10.40.50.30.3
Time in open arm before self-admin0.30.40.9-1.01.01.0-0.90.40.00.0-0.0-0.6-0.00.5-0.40.1
Time in open arm after self-admin0.20.20.4-0.40.40.6-0.6-0.4-0.2-0.20.5-0.4-0.5-0.3-0.4-0.1
Bone: periosteal estimation0.30.61.00.6-0.6-1.01.00.50.80.8-0.91.00.90.70.90.3
Bone: periosteal perimeter0.30.50.90.7-0.7-0.70.70.20.80.8-0.61.00.60.40.80.6
Bone: post-yield work7.511.019.12.4-2.4-2.83.02.13.83.8-3.64.43.73.04.03.2
Progressive ratio test 1 active lever presses0.20.20.40.7-0.7-0.60.60.3-0.3-0.3-0.40.20.40.30.40.4
Progressive ratio test 1 breakpoint0.10.20.40.6-0.6-0.50.60.2-0.3-0.3-0.40.20.30.20.30.4
Progressive ratio test 1 inactive lever presses0.00.10.20.4-0.4-0.30.30.0-0.3-0.3-0.00.00.0-0.10.10.1
Progressive ratio test 2 active lever presses1.11.33.31.8-1.8-1.71.71.0-0.9-0.9-0.80.30.80.60.60.6
Progressive ratio test 2 breakpoint1.01.23.01.7-1.7-1.61.60.9-0.9-0.9-0.70.20.70.50.50.5
Progressive ratio test 2 inactive lever presses2.64.29.63.1-3.1-3.02.92.3-1.3-1.3-1.60.31.41.41.00.8
Incentive Sensitization - Responses0.30.50.70.7-0.7-0.80.80.40.50.5-0.70.80.70.50.80.8
Incentive Sensitization - Breakpoint0.40.50.90.9-0.9-0.90.90.50.30.3-0.80.80.80.60.80.7
Sum of active levers in priming session hrs 5-64.44.17.4-1.41.41.2-1.3-2.4-1.8-1.82.4-1.7-2.3-2.7-2.2-2.7
Progressive ratio2.03.26.40.7-0.7-0.91.10.92.42.4-1.92.51.91.62.32.1
Food seeking constrained by brief footshock0.10.10.4-0.70.70.5-0.5-0.20.10.10.2-0.2-0.2-0.2-0.10.0
Seeking ratio, punishment vs. effort1.21.74.3-0.70.70.8-0.9-0.2-1.9-1.91.2-2.1-1.3-0.8-1.7-1.3
Retroperitoneal fat weight2.711.524.65.0-5.0-4.64.44.9-2.2-2.2-2.8-0.32.53.11.11.0
Reaction time number correct0.61.11.4-1.01.01.1-1.2-1.1-0.7-0.71.2-1.0-1.2-1.1-1.2-1.1
Reaction time mean minus median0.30.71.9-1.11.10.6-0.6-1.41.01.00.50.8-0.4-0.80.2-0.3
Reaction time mean minus median AUC0.30.81.8-1.31.30.9-0.9-1.30.20.20.9-0.1-0.8-1.1-0.5-0.9
Reaction time num false alarms0.20.30.8-0.90.90.5-0.60.5-0.1-0.10.1-0.7-0.10.3-0.5-0.6
Reaction time num false alarms AUC0.30.52.0-1.41.40.9-0.90.20.30.30.2-0.5-0.20.1-0.5-0.6
Reaction time trials correct on left0.61.11.4-1.01.01.1-1.2-1.1-0.7-0.71.2-1.0-1.2-1.1-1.2-1.1
Reaction time trials on left0.71.31.7-1.11.11.2-1.3-1.2-0.7-0.71.3-1.1-1.3-1.2-1.2-1.2
Reaction time mean0.00.10.20.2-0.2-0.50.4-0.20.20.2-0.10.40.2-0.10.2-0.1
Reaction time mean AUC0.10.20.50.4-0.4-0.70.70.10.40.4-0.40.60.40.10.4-0.1
Median of all reaction times0.20.30.80.7-0.7-0.90.90.30.20.2-0.50.50.50.30.50.1
Reaction time omissions0.40.61.6-1.31.30.8-0.8-0.90.70.70.60.3-0.5-0.7-0.1-0.4
Reaction time false alarm rate0.20.20.7-0.70.70.2-0.20.80.40.4-0.4-0.10.40.70.0-0.1
Reaction time premature initiation rate1.52.05.7-2.02.02.4-2.3-1.50.50.51.2-0.6-1.2-1.0-0.8-0.0
Reaction time premature initiations2.44.39.7-2.72.73.1-3.0-2.40.10.12.1-1.3-2.0-1.8-1.6-0.9
Std. dev. reaction times0.10.20.7-0.50.50.2-0.2-0.80.50.50.30.4-0.3-0.60.1-0.3
Reaction time trials completed0.71.31.7-1.11.11.2-1.3-1.2-0.7-0.71.3-1.1-1.3-1.2-1.2-1.2
Reaction time trials AUC0.51.01.3-1.01.01.1-1.2-1.0-0.7-0.71.1-1.0-1.1-1.0-1.1-1.0
Run reversals in cocaine runway, females1.41.43.2-0.40.4-0.10.21.01.81.8-1.21.41.21.41.31.1
Run reversals in cocaine runway, males2.02.03.6-1.11.10.9-1.0-0.8-1.8-1.81.4-1.8-1.4-1.3-1.8-1.9
Latency to leave start box in cocaine runway1.41.62.11.0-1.0-1.21.31.31.11.1-1.41.41.41.31.41.2
Latency to leave start box in cocaine runway, F0.91.01.40.7-0.7-0.90.91.00.90.9-1.21.11.21.11.10.9
Latency to leave start box in cocaine runway, M0.20.20.30.2-0.2-0.40.40.40.50.5-0.40.50.40.30.50.3
Std. dev. time between licks in bursts0.50.71.3-1.11.11.2-1.2-0.1-0.4-0.40.7-1.0-0.7-0.4-0.8-0.5
Total sessions with >9 infusions0.81.01.80.7-0.7-0.70.80.80.90.9-1.21.21.21.01.31.3
Short access day 1 total inactive lever presses0.81.12.41.5-1.5-1.41.31.5-0.4-0.4-1.00.20.91.00.50.5
Short access day 10 total inactive lever presses0.00.10.60.1-0.1-0.30.30.8-0.2-0.2-0.3-0.10.20.40.00.0
Short access day 1 total infusions1.82.43.71.7-1.7-1.81.81.90.50.5-1.81.21.81.81.51.4
Short access day 10 total infusions3.74.86.61.9-1.9-2.12.22.11.51.5-2.52.42.52.32.62.5
Short access total infusions1.82.33.21.3-1.3-1.41.51.61.01.0-1.81.61.81.71.71.8
Short access day 1 locomotion1.21.52.61.4-1.4-1.51.51.60.00.0-1.30.81.31.31.11.1
Short access day 10 total locomotion1.12.03.31.5-1.5-1.81.81.60.40.4-1.61.21.61.51.41.0
Short access total locomotion1.72.03.31.6-1.6-1.81.81.70.30.3-1.61.11.61.51.41.2
One hour access (0.3 mA shock)2.12.45.12.3-2.3-2.22.12.0-1.3-1.3-1.2-0.11.11.20.50.6
Compulsive drug intake2.42.86.2-2.32.32.5-2.4-1.6-0.0-0.01.6-1.2-1.6-1.3-1.4-0.9
One hour access (shock baseline)2.74.19.33.0-3.0-3.12.92.3-1.2-1.2-1.60.41.51.51.00.6
Social response proportion0.10.10.6-0.00.00.3-0.3-0.80.20.20.30.2-0.2-0.60.10.4
Social responses0.30.40.7-0.50.50.8-0.8-0.7-0.5-0.50.7-0.5-0.7-0.8-0.5-0.1
Social time0.50.71.2-0.90.91.1-1.1-0.9-0.6-0.60.9-0.7-0.9-0.9-0.8-0.3
Soleus weight0.92.66.21.9-1.9-2.22.02.5-1.5-1.5-1.3-0.61.21.50.1-0.5
Bone: stiffness0.61.03.2-0.10.10.00.1-0.61.81.8-0.51.70.60.11.21.1
Tibialis anterior weight4.515.134.2-5.95.94.9-4.8-5.10.80.83.6-0.9-3.4-3.9-2.3-2.9
Time to tail flick, vehicle, before self-admin0.30.30.70.1-0.1-0.30.30.10.80.8-0.60.80.70.50.70.6
Time to tail flick, vehicle, after self-admin1.52.04.50.2-0.2-0.40.50.92.12.1-1.51.81.61.61.71.6
Time to tail flick, test, before self-admin2.82.95.01.4-1.4-1.61.72.21.01.0-2.11.42.12.21.71.6
Time to tail flick, test, after self-admin0.10.10.30.1-0.10.1-0.1-0.5-0.4-0.40.4-0.3-0.4-0.5-0.3-0.3
Delta time to tail flick, vehicle, before/after SA0.50.51.40.0-0.00.10.00.41.21.2-0.60.80.60.70.80.9
Delta time to tail flick, test, before/after SA5.25.38.4-1.71.72.0-2.1-2.8-1.9-1.92.8-2.1-2.8-2.9-2.5-2.4
Tibia length0.61.64.2-1.31.30.7-0.8-2.0-0.6-0.61.3-0.4-1.3-1.9-1.0-1.8
Ambulatory time before self-admin0.30.51.10.6-0.6-0.70.8-0.10.80.8-0.51.10.60.20.80.5
Ambulatory time after self-admin0.70.81.81.3-1.3-1.21.20.70.30.3-0.70.80.70.50.80.7
Bone: tissue strength0.10.10.10.3-0.3-0.30.30.20.30.3-0.30.40.30.20.40.4
Total heroin consumption1.11.33.6-1.41.41.5-1.4-1.91.11.10.90.3-0.8-1.1-0.2-0.3
Bone: trabecular number1.01.64.00.8-0.8-0.60.80.21.61.6-1.11.91.10.71.72.0
Bone: trabecular spacing0.10.10.4-0.20.20.2-0.20.3-0.4-0.40.1-0.6-0.10.2-0.4-0.4
Bone: trabecular thickness1.11.42.21.4-1.4-1.21.31.20.70.7-1.21.11.21.11.31.5
Bone: trabecular tissue density0.81.22.61.0-1.0-1.51.31.2-1.6-1.6-0.3-0.90.20.4-0.6-1.2
Water consumed over 24 hours0.40.51.3-0.80.81.1-1.1-1.10.20.20.8-0.2-0.8-0.7-0.40.2
Number of responses in last shaping day0.10.10.3-0.20.20.5-0.5-0.3-0.4-0.40.5-0.5-0.5-0.3-0.4-0.1