Hub : Traits

Conditioned locomotion

Tags: Behavior · Locomotion

Project: p50_paul_meyer_2020

7 loci · 10 genes with independent associations · 11 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr1	195496403	196893216	1	1	1.24e-07	2.90e-07	4.40e-01	Gpr26
2	chr1	197835237	200586301	5	4	8.27e-10	3.68e-10	7.69e-01	Dock1 Insyn2a LOC102551963 Uros
3	chr2	144511896	145907690	1	1	2.40e-08	2.43e-01	1.00e+00	Mindy4b
4	chr7	92127461	93066096	1	1	6.90e-22	2.45e-01	1.00e+00	Ndufb9
5	chr9	72835349	74094385	1	1	1.63e-07	4.14e-04	1.00e+00	Creb1
6	chr9	83390749	84777604	1	1	0.00e+00	3.11e-02	1.00e+00	Retreg2
7	chr17	61510864	62906219	1	1	3.09e-41	1.94e-02	1.26e-02	Ccny

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	968.25	4	4	40	-0.99	1.31e-02	Creb1 Mindy4b Ndufb9 Retreg2
BMI without tail	36009.96	4	3	30	1	2.45e-03	Ccny Mindy4b Ndufb9 Retreg2
Body weight	8.04	3	2	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Epididymis fat weight	36170.21	3	2	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Glucose	1186.24	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Heart weight	4511.78	3	2	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Left kidney weight	35317.16	4	2	20	-1	2.83e-03	Ccny Mindy4b Ndufb9 Retreg2
Right kidney weight	38957.32	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Tail length	30712.2	3	2	20	0	1.00e+00	Ccny Creb1 Retreg2
Length with tail	2050.17	3	2	20	0	1.00e+00	Creb1 Ndufb9 Retreg2
Length without tail	32335.28	4	2	20	-1	3.32e-03	Ccny Mindy4b Ndufb9 Retreg2
Liver weight, left	4845.91	3	2	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Liver weight, right	88.25	3	1	10	0	1.00e+00	Ccny Ndufb9 Retreg2
Parametrial fat weight	311.74	2	1	10	0	1.00e+00	Ccny Retreg2
Retroperitoneal fat weight	4015.82	4	1	10	1	1.48e-04	Gpr26 Mindy4b Retreg2 Uros
Intraocular pressure	40071.91	1	1	10	0	1.00e+00	Retreg2
Extensor digitorum longus weight	1562.77	3	1	10	0	1.00e+00	Creb1 Mindy4b Retreg2
Soleus weight	60.1	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Tibialis anterior weight	4881.94	1	1	10	0	1.00e+00	Retreg2
Tibia length	1631.46	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Number of licking bursts	78561.42	2	1	10	0	1.00e+00	Ccny Retreg2
Food consumed during 24 hour testing period	53104.21	2	1	10	0	1.00e+00	Ccny Retreg2
Times rat made contact with spout	158.46	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Mean time between licks in bursts	66503.89	3	1	10	0	1.00e+00	Ccny Ndufb9 Retreg2
Mean num. licks in bursts	71302.54	2	1	10	0	1.00e+00	Ccny Retreg2
Std. dev. time between licks in bursts	94042.02	1	1	10	0	1.00e+00	Retreg2
Water consumed over 24 hours	51711.02	2	1	10	0	1.00e+00	Ccny Retreg2
Patch foraging indifference point 0 sec	115003.89	1	1	10	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	44399.08	3	2	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Indifference point function ln k	47369.79	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Indifference point function log k	47369.79	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Patch foraging total patch changes 0 sec	120264.14	1	1	10	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	3683.47	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Patch foraging total patch changes 18 sec	39261.17	3	1	10	0	1.00e+00	Ccny Ndufb9 Retreg2
Patch foraging total patch changes 24 sec	55719.27	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Patch foraging total patch changes 6 sec	8181.69	4	3	30	0.99	6.41e-03	Ccny Mindy4b Ndufb9 Retreg2
Patch foraging time to switch 0 sec	78314.79	2	2	20	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 0 sec	74407.03	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 12 sec	80953.12	2	2	20	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 18 sec	34430	3	1	10	0	1.00e+00	Ccny Ndufb9 Retreg2
Patch foraging water rate 24 sec	2357.13	2	2	20	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 6 sec	1363.06	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Locomotor activity	35.04	2	1	10	0	1.00e+00	Ccny Retreg2
Locomotor testing distance	29855.65	3	2	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Locomotor testing rearing	76208.69	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Light reinforcement 1	51780.52	3	2	20	0	1.00e+00	Ccny Mindy4b Retreg2
Light reinforcement 2	54020.7	2	2	20	0	1.00e+00	Ccny Retreg2
Reaction time number correct	51168.28	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time mean minus median	68605.03	3	1	10	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time mean minus median AUC	104201.41	2	2	20	0	1.00e+00	Ndufb9 Retreg2
Reaction time num false alarms	28557.11	2	2	20	0	1.00e+00	Ccny Retreg2
Reaction time num false alarms AUC	53265.52	2	2	20	0	1.00e+00	Ccny Retreg2
Reaction time trials correct on left	51168.28	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time trials on left	50013.45	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time mean	31468.26	3	2	20	0	1.00e+00	Ccny Mindy4b Retreg2
Reaction time mean AUC	37788.34	3	2	20	0	1.00e+00	Ccny Mindy4b Retreg2
Median of all reaction times	15724.94	2	2	20	0	1.00e+00	Mindy4b Retreg2
Reaction time omissions	11429.48	3	1	10	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Reaction time false alarm rate	891.26	1	1	10	0	1.00e+00	Retreg2
Reaction time premature initiation rate	12297.62	3	1	10	0	1.00e+00	Ccny Mindy4b Retreg2
Reaction time premature initiations	46242.53	3	1	10	0	1.00e+00	Ccny Mindy4b Retreg2
Std. dev. reaction times	49831.65	3	1	10	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Reaction time trials completed	50013.45	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time trials AUC	50581.81	3	2	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Social response proportion	17656.04	2	1	10	0	1.00e+00	Mindy4b Retreg2
Social responses	2856.43	2	2	20	0	1.00e+00	Ccny Retreg2
Social time	44238.34	1	1	10	0	1.00e+00	Retreg2
Conditioned locomotion	3044.63	2	1	10	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. corrected	21944.02	3	1	10	0	1.00e+00	Ccny LOC102551963 Retreg2
Cocaine response after cond. not corrected	32126.66	2	1	10	0	1.00e+00	LOC102551963 Retreg2
Cocaine response before conditioning	1409.02	2	1	10	0	1.00e+00	Ccny Retreg2
Saline control response	12962.78	1	1	10	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	26708.5	2	1	10	0	1.00e+00	Creb1 Retreg2
Condit. Reinf. active-inactive response ratio	30531.22	3	1	10	0	1.00e+00	Creb1 Ndufb9 Retreg2
Condit. Reinf. active responses	9691.24	1	1	10	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	21056.03	2	1	10	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever presses	7939.8	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. lever reinforcers received	2000.77	1	1	10	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	10912.53	1	1	10	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	24714.14	2	1	10	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. change in total contacts	57393.18	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. index score	23998.4	2	1	10	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. latency score	29242.48	2	1	10	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever contacts	22069.78	1	1	10	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	16773.11	1	1	10	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	104933.78	1	1	10	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	22438.69	2	1	10	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. response bias	5169.79	1	1	10	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	19156.21	8	3	30	1	1.20e-10	Ccny Dock1 Gpr26 Insyn2a LOC102551963 Ndufb9 Retreg2 Uros
Conditioned reinforcement - inactives	31016.47	5	3	30	1	5.30e-05	Ccny Gpr26 Insyn2a Ndufb9 Retreg2
Intermittent access intake day 1-15 change	70205.89	3	2	20	0	1.00e+00	Ccny Mindy4b Retreg2
Intermittent access intake escalation	104774.17	2	1	10	0	1.00e+00	Mindy4b Retreg2
Intermittent access intake escalation 2	54050.4	2	2	20	0	1.00e+00	Ccny Retreg2
Intermitt. access day 1 inactive lever presses	78848.66	3	1	10	0	1.00e+00	Ccny Ndufb9 Retreg2
Intermitt. access day 15 inactive lever presses	104145.18	2	2	20	0	1.00e+00	Ndufb9 Retreg2
Intermitt. access escalation Index	46253.76	4	1	10	-1	2.29e-03	Ccny Mindy4b Ndufb9 Retreg2
Intermittent access day 1 total infusions	31108.45	5	1	10	-1	2.53e-04	Ccny Gpr26 LOC102551963 Mindy4b Retreg2
Intermittent access day 15 total infusions	21919.46	6	1	10	1	9.31e-06	Ccny Gpr26 Insyn2a LOC102551963 Retreg2 Uros
Intermittent access terminal intake (last 3 days)	11892.36	6	1	10	1	2.03e-08	Dock1 Gpr26 Insyn2a LOC102551963 Retreg2 Uros
Intermittent access total infusions	84.74	7	1	10	-0.91	5.72e-04	Ccny Dock1 Gpr26 Insyn2a LOC102551963 Retreg2 Uros
Intermittent access day 1 locomotion	11615.54	8	2	20	-1	1.79e-08	Ccny Dock1 Gpr26 Insyn2a LOC102551963 Mindy4b Retreg2 Uros
Intermittent access day 15 total locomotion	25415.95	6	2	20	1	1.18e-06	Ccny Dock1 Gpr26 LOC102551963 Retreg2 Uros
Intermittent access total locomotion	81.79	9	1	10	0.95	1.99e-05	Creb1 Dock1 Gpr26 Insyn2a LOC102551963 Mindy4b Ndufb9 Retreg2 Uros
Intermittent access standard deviation	100979.14	2	2	20	0	1.00e+00	Ccny Retreg2
Cocaine induced anxiety	53447.41	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Post-drug Anxiety	10242.99	2	2	20	0	1.00e+00	Ndufb9 Retreg2
Baseline Anxiety	34558.77	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Lifetime Intake	772.44	7	2	20	-0.98	5.57e-06	Ccny Dock1 Gpr26 Insyn2a LOC102551963 Retreg2 Uros
Incentive Sensitization - Responses	40905.93	4	3	30	-1	3.55e-03	Ccny Mindy4b Ndufb9 Retreg2
Incentive Sensitization - Breakpoint	35708.82	4	3	30	-1	3.72e-03	Ccny Mindy4b Ndufb9 Retreg2
Progressive ratio test 1 active lever presses	11108.87	7	2	20	1	4.10e-10	Ccny Dock1 Gpr26 Insyn2a LOC102551963 Ndufb9 Retreg2
Progressive ratio test 1 breakpoint	12043.64	7	2	20	1	7.03e-09	Ccny Dock1 Gpr26 Insyn2a LOC102551963 Ndufb9 Retreg2
Progressive ratio test 1 inactive lever presses	37783.01	4	3	30	1	1.48e-03	Ccny Insyn2a Ndufb9 Retreg2
Progressive ratio test 2 active lever presses	5734.59	8	2	20	-0.99	2.74e-08	Ccny Dock1 Gpr26 Insyn2a LOC102551963 Mindy4b Retreg2 Uros
Progressive ratio test 2 breakpoint	3512.43	8	2	20	-0.99	7.91e-08	Ccny Dock1 Gpr26 Insyn2a LOC102551963 Mindy4b Retreg2 Uros
Progressive ratio test 2 inactive lever presses	18238.17	7	2	20	1	2.50e-09	Ccny Dock1 Gpr26 Insyn2a LOC102551963 Ndufb9 Retreg2
Total sessions with >9 infusions	813.75	8	2	20	-0.97	2.82e-06	Ccny Dock1 Gpr26 Insyn2a LOC102551963 Mindy4b Retreg2 Uros
Short access day 1 total inactive lever presses	28610.09	4	3	30	-1	1.68e-03	Ccny Mindy4b Ndufb9 Retreg2
Short access day 10 total inactive lever presses	108624.06	2	2	20	0	1.00e+00	Ccny Retreg2
Short access day 1 total infusions	12419.24	7	2	20	-0.99	1.54e-07	Ccny Dock1 Gpr26 Insyn2a LOC102551963 Retreg2 Uros
Short access day 10 total infusions	12723.95	6	2	20	-0.99	4.17e-05	Ccny Gpr26 Insyn2a LOC102551963 Ndufb9 Retreg2
Short access total infusions	3412.84	8	2	20	-0.99	1.16e-07	Ccny Dock1 Gpr26 Insyn2a LOC102551963 Mindy4b Retreg2 Uros
Short access day 1 locomotion	9353.54	7	3	30	1	8.61e-11	Ccny Dock1 Insyn2a LOC102551963 Ndufb9 Retreg2 Uros
Short access day 10 total locomotion	60541.4	3	3	30	0	1.00e+00	Ccny Mindy4b Retreg2
Short access total locomotion	6835.44	8	1	10	1	2.66e-12	Dock1 Gpr26 Insyn2a LOC102551963 Mindy4b Ndufb9 Retreg2 Uros
Compulsive drug intake	21819.64	3	1	10	0	1.00e+00	Ccny Ndufb9 Retreg2
One hour access (0.3 mA shock)	3242.98	3	2	20	0	1.00e+00	Ccny Mindy4b Retreg2
One hour access (shock baseline)	17537.31	6	1	10	1	3.83e-08	Ccny Dock1 Insyn2a LOC102551963 Retreg2 Uros
Number of responses in last shaping day	17141.46	3	2	20	0	1.00e+00	Ccny Mindy4b Retreg2
Context. condit. distance diff. score	970.59	1	1	10	0	1.00e+00	Retreg2
Locomotion velocity, session 1	7315.11	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Locomotion distance, session 1	2213.01	2	1	10	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 2	9358	1	1	10	0	1.00e+00	Retreg2
Locomotion distance, session 2	1206.44	2	1	10	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 3	2332.53	1	1	10	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	10	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	5866.4	1	1	10	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	12131.92	1	1	10	0	1.00e+00	Retreg2
Locomotion velocity, session 7	1310.17	1	1	10	0	1.00e+00	Retreg2
Locomotion distance, session 7	1879.14	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving bouts, day 7	5257.18	2	2	20	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving duration, day 7	4446.48	2	2	20	0	1.00e+00	Ndufb9 Retreg2
Locomotion velocity, session 8	950.4	2	1	10	0	1.00e+00	Ccny Retreg2
Locomotion distance, session 8	673.32	1	1	10	0	1.00e+00	Retreg2
Degree of sensitization distance	15309.16	1	1	10	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	4256.13	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active minus inactive responses	1380.95	3	1	10	0	1.00e+00	Ccny Mindy4b Retreg2
Condit. Reinf. active-inactive response ratio	553.67	2	1	10	0	1.00e+00	Mindy4b Retreg2
Condit. Reinf. active responses	3895.25	3	1	10	0	1.00e+00	Ccny Mindy4b Retreg2
Condit. Reinf. inactive responses	9694.1	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Incentive salience index mean	7397.37	2	1	10	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever presses	21433.81	1	1	10	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 1	41873.03	1	1	10	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	17766.61	2	1	10	0	1.00e+00	Creb1 Retreg2
Total zone transitions, hab. session 1	916.07	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 1	849.35	2	1	10	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 1	571.33	2	1	10	0	1.00e+00	Ccny Retreg2
Time in familiar zone, hab. session 2	23379.25	1	1	10	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	24924.95	1	1	10	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	143.96	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 2	51.92	2	1	10	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 2	77.91	2	1	10	0	1.00e+00	Ccny Retreg2
Novel to familiar place preference ratio	27759.88	2	1	10	0	1.00e+00	Ccny Retreg2
Novelty place preference	27195.73	2	1	10	0	1.00e+00	Ccny Retreg2
Time in novel zone, NPP test	40844.77	1	1	10	0	1.00e+00	Retreg2
Total zone transitions, NPP test	4127.68	2	2	20	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, NPP test	3566.83	2	2	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, NPP test	2031.76	2	2	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever latency	2195.61	1	1	10	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	8.04	1	0	0	0	1.00e+00	Ccny
Pavlov. Cond. change in total contacts	2273.55	2	1	10	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. index score	1769.33	1	1	10	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	1841.19	1	1	10	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	1520.48	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. magazine entry number	1086.53	2	1	10	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. intertrial magazine entries	269.44	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	1940.27	1	1	10	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	2606.99	1	1	10	0	1.00e+00	Retreg2
Bone: apparent density	11138.75	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Bone surface	12566.7	2	1	10	0	1.00e+00	Gpr26 Retreg2
Bone volume	16919.4	2	1	10	0	1.00e+00	Gpr26 Retreg2
Bone: connectivity density	3557.17	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical apparent density	22636.78	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical area	9468.26	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	619.93	3	1	10	0	1.00e+00	Creb1 Ndufb9 Retreg2
Bone: cortical porosity	1609.67	3	1	10	0	1.00e+00	Creb1 Ndufb9 Retreg2
Bone: cortical thickness	817.52	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical thickness	6100.69	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical tissue density	16155.62	3	1	10	0	1.00e+00	Ccny Ndufb9 Retreg2
Bone: elastic displacement	29626.25	1	1	10	0	1.00e+00	Retreg2
Bone: elastic work	1494.59	1	1	10	0	1.00e+00	Retreg2
Bone: endosteal estimation	17631.97	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Bone: endosteal perimeter	44697.39	1	1	10	0	1.00e+00	Retreg2
Bone: final force	7031.22	1	1	10	0	1.00e+00	Retreg2
Bone: final moment	1042.62	1	1	10	0	1.00e+00	Retreg2
Bone: marrow area	18537.3	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum diameter	12203.48	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum force	34553.99	1	1	10	0	1.00e+00	Retreg2
Bone: maximum moment	24715.64	1	1	10	0	1.00e+00	Retreg2
Bone: minimum diameter	17196.64	1	1	10	0	1.00e+00	Retreg2
Bone: periosteal estimation	38190.5	1	1	10	0	1.00e+00	Retreg2
Bone: periosteal perimeter	43183.28	1	1	10	0	1.00e+00	Retreg2
Bone: post-yield work	50847.58	1	1	10	0	1.00e+00	Retreg2
Bone: stiffness	35564.91	1	1	10	0	1.00e+00	Retreg2
Bone: tissue strength	12264.67	1	1	10	0	1.00e+00	Retreg2
Bone: trabecular number	20584.56	2	2	20	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular spacing	15655.12	2	2	20	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular thickness	33264.33	1	1	10	0	1.00e+00	Retreg2
Bone: trabecular tissue density	17885.93	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Breakpoint value in progressive ratio session	56221.29	2	1	10	0	1.00e+00	Ccny Retreg2
Distance traveled before self-admin	33521.89	4	2	20	1	1.36e-03	Ccny Ndufb9 Retreg2 Uros
Distance traveled after self-admin	50469.31	2	2	20	0	1.00e+00	Ccny Retreg2
Delta time in closed arm before/after self-admin	1030.46	2	2	20	0	1.00e+00	Ccny Retreg2
Delta time in open arm before/after self-admin	27441.91	2	2	20	0	1.00e+00	Ccny Retreg2
Diff in mean of infusions in LGA sessions	108490.77	1	1	10	0	1.00e+00	Retreg2
Extinction: sum of active levers before priming	30592.97	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Active lever presses in extinction session 6	1673.08	2	2	20	0	1.00e+00	Ccny Retreg2
Delta distance traveled before/after self-admin	4205.11	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Delta ambulatory time before/after self-admin	32036.91	3	2	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Time in closed arm before self-admin	44143.36	2	2	20	0	1.00e+00	Ccny Retreg2
Time in closed arm after self-admin	9901.19	2	2	20	0	1.00e+00	Ccny Retreg2
Time in open arm before self-admin	5802.54	5	3	30	-0.99	3.95e-05	Ccny Dock1 Insyn2a Ndufb9 Retreg2
Time in open arm after self-admin	669.46	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Sum of active levers in priming session hrs 5-6	1945.79	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Time to tail flick, vehicle, before self-admin	17290.24	3	2	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Time to tail flick, vehicle, after self-admin	23668.56	5	2	20	1	1.75e-04	Ccny Creb1 Mindy4b Ndufb9 Retreg2
Time to tail flick, test, before self-admin	10954.71	3	2	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Time to tail flick, test, after self-admin	1221.25	5	4	40	0.97	5.05e-03	Ccny Creb1 Mindy4b Ndufb9 Retreg2
Delta time to tail flick, vehicle, before/after SA	12302.72	3	2	20	0	1.00e+00	Ccny Mindy4b Retreg2
Delta time to tail flick, test, before/after SA	11377.49	5	1	10	1	1.52e-04	Ccny Creb1 Mindy4b Ndufb9 Retreg2
Ambulatory time before self-admin	57049.52	3	2	20	0	1.00e+00	Ccny LOC102551963 Retreg2
Ambulatory time after self-admin	44153.3	2	2	20	0	1.00e+00	Ccny Retreg2
Total heroin consumption	547.18	2	2	20	0	1.00e+00	Ccny Retreg2
Area under the delay curve	27209.19	3	1	10	0	1.00e+00	Ccny Mindy4b Retreg2
Delay disc. indifference point, 0s delay	4743.52	2	1	10	0	1.00e+00	Mindy4b Retreg2
Delay disc. indifference point, 16s delay	24960.64	3	2	20	0	1.00e+00	Ccny Mindy4b Retreg2
Delay disc. indifference point, 2s delay	417.74	2	1	10	0	1.00e+00	Mindy4b Retreg2
Delay disc. indifference point, 24s delay	50025	2	2	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 4s delay	656.7	4	2	20	-0.97	3.26e-02	Ccny Mindy4b Ndufb9 Retreg2
Delay disc. indifference point, 8s delay	101423.99	1	1	10	0	1.00e+00	Retreg2
Delay discount exponential model param	30110.83	2	1	10	0	1.00e+00	Mindy4b Retreg2
Delay discount hyperbolic model param	22862.83	2	1	10	0	1.00e+00	Mindy4b Retreg2
Fecal boli incidents, locomotor time 1	75084.64	2	1	10	0	1.00e+00	Ccny Retreg2
Change in fecal boli incidents, locomotor task	5920.26	4	3	30	0.99	1.11e-02	Ccny Mindy4b Ndufb9 Retreg2
Time >=10cm from walls, locomotor time 1	12334.02	4	2	20	-1	5.57e-04	Ccny LOC102551963 Mindy4b Retreg2
Bouts of movement, locomotor time 1	20842.46	2	2	20	0	1.00e+00	Ccny Retreg2
Total resting periods, locomotor time 1	5936.78	2	2	20	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 1	25327.02	3	1	10	0	1.00e+00	Ccny Ndufb9 Retreg2
Distance moved, locomotor task time 1	53112.82	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Vertical activity count, locomotor time 1	109531.92	2	1	10	0	1.00e+00	LOC102551963 Retreg2
Time >=10cm from walls, locomotor time 2	54002.04	3	2	20	0	1.00e+00	Ccny Mindy4b Retreg2
Bouts of movement, locomotor time 2	58111.8	3	2	20	0	1.00e+00	Ccny Mindy4b Retreg2
Total resting periods, locomotor time 2	63368.65	3	2	20	0	1.00e+00	Ccny Mindy4b Retreg2
Rest time, locomotor task time 2	27936.17	3	2	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Distance moved, locomotor task time 2	11481.69	3	2	20	0	1.00e+00	Ccny Mindy4b Retreg2
Vertical activity count, locomotor time 2	34623.57	4	3	30	-1	2.67e-03	Ccny LOC102551963 Mindy4b Retreg2
Weight adjusted by age	54026.61	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Seeking ratio, delayed vs. immediate footshock	16476.76	3	2	20	0	1.00e+00	Ccny Mindy4b Retreg2
Locomotion in novel chamber	2346.7	6	3	30	-0.99	2.82e-05	Ccny Dock1 Gpr26 Ndufb9 Retreg2 Uros
Locomotion in novel chamber post-restriction	51551.01	3	1	10	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio	52658.05	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Food seeking constrained by brief footshock	3673.46	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, punishment vs. effort	39437.56	3	3	30	0	1.00e+00	Ccny Ndufb9 Retreg2
Run reversals in cocaine runway, females	18598.36	2	1	10	0	1.00e+00	Ccny Retreg2
Run reversals in cocaine runway, males	9993.2	3	2	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Latency to leave start box in cocaine runway	29317.55	2	2	20	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway, F	9470.37	3	2	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Latency to leave start box in cocaine runway, M	2456.15	3	2	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Co content in liver	4721.74	1	1	10	0	1.00e+00	Retreg2
Cu content in liver	89.33	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Fe content in liver	5656.2	1	1	10	0	1.00e+00	Retreg2
K content in liver	6593.53	1	1	10	0	1.00e+00	Retreg2
Mg content in liver	24493.99	1	1	10	0	1.00e+00	Retreg2
Mn content in liver	2219.37	2	2	20	0	1.00e+00	Ndufb9 Retreg2
Na content in liver	8325.4	2	1	10	0	1.00e+00	Ndufb9 Retreg2
Rb content in liver	241.33	2	2	20	0	1.00e+00	Ndufb9 Retreg2
Se content in liver	8.64	1	0	0	0	1.00e+00	Ndufb9
Zn content in liver	7891.81	2	2	20	0	1.00e+00	Ndufb9 Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.2
Adipose	alternative TSS	2	0.1	1.26
Adipose	gene expression	0	0	1.24
Adipose	isoform ratio	0	0	1.19
Adipose	intron excision ratio	0	0	1.11
Adipose	mRNA stability	1	0	1.28
BLA	alternative polyA	0	0	1.16
BLA	alternative TSS	0	0	1.39
BLA	gene expression	0	0	1.29
BLA	isoform ratio	0	0	1.32
BLA	intron excision ratio	1	0	1.17
BLA	mRNA stability	0	0	1.3
Brain	alternative polyA	0	0	1.18
Brain	alternative TSS	0	0	1.28
Brain	gene expression	0	0	1.25
Brain	isoform ratio	0	0	1.28
Brain	intron excision ratio	0	0	1.15
Brain	mRNA stability	0	0	1.27
Eye	alternative polyA	0	0	1.24
Eye	alternative TSS	0	0	1.32
Eye	gene expression	0	0	1.3
Eye	isoform ratio	0	0	1.36
Eye	intron excision ratio	0	0	1.18
Eye	mRNA stability	0	0	1.36
IC	alternative polyA	0	0	1.26
IC	alternative TSS	0	0	1.26
IC	gene expression	0	0	1.28
IC	isoform ratio	0	0	1.24
IC	intron excision ratio	0	0	1.21
IC	mRNA stability	0	0	1.3
IL	alternative polyA	0	0	1.15
IL	alternative TSS	0	0	1.1
IL	gene expression	0	0	1.24
IL	isoform ratio	1	0.1	1.26
IL	intron excision ratio	0	0	1.08
IL	mRNA stability	0	0	1.36
LHb	alternative polyA	0	0	1.17
LHb	alternative TSS	0	0	1.21
LHb	gene expression	0	0	1.27
LHb	isoform ratio	0	0	1.19
LHb	intron excision ratio	0	0	1.08
LHb	mRNA stability	0	0	1.34
Liver	alternative polyA	0	0	1.19
Liver	alternative TSS	0	0	1.26
Liver	gene expression	0	0	1.25
Liver	isoform ratio	0	0	1.23
Liver	intron excision ratio	0	0	1.16
Liver	mRNA stability	0	0	1.23
NAcc	alternative polyA	1	0	18.38
NAcc	alternative TSS	1	0	1.29
NAcc	gene expression	1	0	1.27
NAcc	isoform ratio	0	0	1.33
NAcc	intron excision ratio	1	0	1.2
NAcc	mRNA stability	0	0	1.3
OFC	alternative polyA	0	0	1.17
OFC	alternative TSS	0	0	1.4
OFC	gene expression	1	0	1.3
OFC	isoform ratio	0	0	1.27
OFC	intron excision ratio	0	0	1.2
OFC	mRNA stability	0	0	1.36
PL	alternative polyA	0	0	1.29
PL	alternative TSS	0	0	1.35
PL	gene expression	0	0	1.26
PL	isoform ratio	0	0	1.33
PL	intron excision ratio	0	0	1.18
PL	mRNA stability	0	0	1.32
pVTA	alternative polyA	1	0	1.31
pVTA	alternative TSS	0	0	1.38
pVTA	gene expression	1	0	1.32
pVTA	isoform ratio	0	0	1.33
pVTA	intron excision ratio	0	0	1.19
pVTA	mRNA stability	0	0	1.32
RMTg	alternative polyA	0	0	1.13
RMTg	alternative TSS	0	0	1.19
RMTg	gene expression	0	0	1.27
RMTg	isoform ratio	0	0	1.2
RMTg	intron excision ratio	0	0	1.15
RMTg	mRNA stability	0	0	1.23