Hub : Traits

Parametrial fat weight

Tags: Physiology · Weight

Project: dissection

236 significantly associated models · 62 unique genes

Significant Loci

# chr p0 p1 # assoc genes # joint models best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 254740406 256136868 1 1 2.5e-07 9.0e-07 0.42 97 Casp7
2 1 257808644 260518987 15 4 1.4e-18 2.8e-19 1.00 100 Fam204a Cacul1 Nanos1 Sfxn4
3 3 129554891 132693612 15 5 4.8e-11 1.8e-11 1.00 100 Kif16b Pcsk2 Dstn Dtd1 Otor
4 6 25869940 29090273 11 4 1.5e-10 5.2e-09 1.00 100 Ncoa1 Efr3b Itsn2 NA
5 7 16845355 16970279 1 1 6.9e-13 NaN NA NA NA
6 10 56067111 58495301 18 1 1.9e-08 3.5e-08 1.00 100 Cyb5d2
7 11 39057816 40174684 1 1 1.8e-09 1.9e-01 1.00 100 Epha6

p0: physical position of the start of the locus. p1: physical position of the end of the locus. # joint models: number of models selected by step-wise conditional analysis.

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
BMI with tail 16.4 36 27 158.8 0.98 4.7e-102 Adcy3 Ncoa1 Kif16b Snrpb2 Pcsk2 Dstn Rrbp1 Kat14 Dzank1 Rbbp9 Sec23b Dtd1 Pdzd8 Rab11fip2 Fam204a Prlhr Cacul1 Dennd10 Prdx3 Grk5 Efr3b Nanos1 Zfp133 Mgme1 Otor Zfp950 Ces2c Sfxn4 Smim26 Itsn2 Casp7 NA NA NA NA NA
BMI without tail 15.0 29 15 88.2 0.90 1.4e-47 Kif16b Snrpb2 Pcsk2 Dstn Rrbp1 Dzank1 Rbbp9 Sec23b Dtd1 Pdzd8 Rab11fip2 Fam204a Prlhr Cacul1 Dennd10 Prdx3 Grk5 Nanos1 Zfp133 Mgme1 Otor Zfp950 Ces2c Sfxn4 NA NA NA NA NA
Body weight 15.3 42 32 188.2 0.97 5.1e-99 Dnajc27 Adcy3 Ncoa1 Kif16b Snrpb2 Klhl29 Pcsk2 Dstn Rrbp1 Kat14 Dzank1 Rbbp9 Sec23b Dtd1 Pdzd8 Rab11fip2 Fam204a Prlhr Cacul1 Dennd10 Prdx3 Grk5 Dtnb Efr3b Nanos1 Zfp133 Mgme1 Otor Zfp950 Ces2c Sfxn4 Smim26 Itsn2 Fam228b Cenpo Casp7 NA NA NA NA NA NA
Epididymis fat weight 21.5 43 34 200.0 0.93 3.1e-81 Dnajc27 Adcy3 Ncoa1 Kif16b Snrpb2 Klhl29 Pcsk2 Dstn Rrbp1 Kat14 Dzank1 Rbbp9 Sec23b Dtd1 Pdzd8 Rab11fip2 Fam204a Prlhr Cacul1 Dennd10 Prdx3 Grk5 Dtnb Efr3b Nanos1 Zfp133 Mgme1 Otor Zfp950 Ces2c Sfxn4 Smim26 Itsn2 Fam228b Cenpo Casp7 NA NA NA NA NA NA Ubxn2a
Glucose 9.9 5 0 0.0 0.99 4.9e-10 Cacul1 Dennd10 Zfp950 Ces2c Sfxn4
Heart weight 10.7 11 0 0.0 1.00 6.4e-24 Rab11fip2 Cacul1 Dennd10 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 NA NA NA
Left kidney weight 12.5 14 13 76.5 0.87 8.4e-15 Rab11fip2 Prlhr Cacul1 Dennd10 Prdx3 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 NA NA NA NA
Right kidney weight 12.5 14 13 76.5 0.86 5.9e-14 Rab11fip2 Prlhr Cacul1 Dennd10 Prdx3 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 NA NA NA NA
Tail length 91.1 1 1 5.9 0.00 1.0e+00 NA
Length with tail 4.5 8 0 0.0 0.88 1.3e-06 Kif16b Cacul1 Nanos1 Otor Zfp950 Sfxn4 NA NA
Length without tail 14.2 7 1 5.9 0.84 4.3e-05 Rab11fip2 Prlhr Cacul1 Zfp950 Sfxn4 NA NA
Liver weight, left 10.8 5 1 5.9 0.81 4.2e-04 Rab11fip2 Prlhr Cacul1 Sfxn4 NA
Liver weight, right 12.8 13 4 23.5 1.00 5.3e-44 Pdzd8 Rab11fip2 Prlhr Cacul1 Dennd10 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 Casp7 NA NA
Retroperitoneal fat weight 30.1 43 42 247.1 0.98 1.2e-128 Dnajc27 Adcy3 Ncoa1 Kif16b Snrpb2 Klhl29 Pcsk2 Dstn Rrbp1 Kat14 Dzank1 Rbbp9 Sec23b Dtd1 Pdzd8 Rab11fip2 Fam204a Prlhr Cacul1 Dennd10 Prdx3 Grk5 Dtnb Efr3b Nanos1 Zfp133 Mgme1 Otor Zfp950 Ces2c Sfxn4 Smim26 Itsn2 Fam228b Cenpo Casp7 NA NA NA NA NA NA Ubxn2a
Intraocular pressure 29.4 1 1 5.9 0.00 1.0e+00 NA
Extensor digitorum longus weight 5.0 19 1 5.9 0.97 1.6e-27 Pitpnm3 Ube2g1 RGD1304728 Slc13a5 Fbxo39 Tekt1 Spns3 Ankfy1 Atp2a3 Camkk1 Tax1bp3 Zzef1 Cyb5d2 Sfxn4 Xaf1 Spns2 NA NA NA
Soleus weight 6.9 6 1 5.9 -0.09 8.1e-01 Ncoa1 Rab11fip2 Prdx3 Tekt1 NA NA
Tibialis anterior weight 6.5 19 1 5.9 0.93 6.7e-23 Pitpnm3 Ube2g1 RGD1304728 Slc13a5 Fbxo39 Tekt1 Smtnl2 Spns3 Ankfy1 Atp2a3 Camkk1 P2rx5 Tax1bp3 Zzef1 Cyb5d2 Xaf1 Spns2 NA NA
Tibia length 7.7 3 0 0.0 -0.89 4.1e-02 Kif16b Otor NA
Number of licking bursts 242.4 1 1 5.9 0.00 1.0e+00 NA
Food consumed during 24 hour testing period 17.5 1 0 0.0 0.00 1.0e+00 NA
Times rat made contact with spout 50.4 2 1 5.9 0.00 1.0e+00 Epha6 NA
Mean time between licks in bursts 90.5 1 1 5.9 0.00 1.0e+00 NA
Mean num. licks in bursts 258.2 1 1 5.9 0.00 1.0e+00 NA
Std. dev. time between licks in bursts 291.0 1 1 5.9 0.00 1.0e+00 NA
Water consumed over 24 hours 15.6 1 0 0.0 0.00 1.0e+00 Epha6
Indifference point 0 sec 21.3 1 1 5.9 0.00 1.0e+00 NA
Indifference point AUC 66.7 1 1 5.9 0.00 1.0e+00 NA
Delay discounting total patch changes 0 sec 10.6 4 1 5.9 0.59 1.6e-01 Cacul1 Grk5 NA NA
Delay discounting total patch changes 12 sec 85.7 2 1 5.9 0.00 1.0e+00 Epha6 NA
Delay discounting total patch changes 18 sec 147.0 2 1 5.9 0.00 1.0e+00 Epha6 NA
Delay discounting total patch changes 24 sec 43.7 1 1 5.9 0.00 1.0e+00 NA
Delay discounting total patch changes 6 sec 44.3 3 1 5.9 -0.55 4.5e-01 Epha6 NA NA
Delay discounting water rate 0 sec 11.8 1 0 0.0 0.00 1.0e+00 NA
Delay discounting water rate 12 sec 44.2 1 1 5.9 0.00 1.0e+00 NA
Delay discounting water rate 18 sec 11.6 8 0 0.0 -0.81 7.2e-04 Kat14 Dzank1 Rbbp9 Sec23b Dtd1 Epha6 Smim26 NA
Delay discounting water rate 24 sec 100.9 1 1 5.9 0.00 1.0e+00 NA
Delay discounting water rate 6 sec 70.2 1 1 5.9 0.00 1.0e+00 NA
Locomotor testing distance 11.5 2 0 0.0 0.00 1.0e+00 Epha6 NA
Locomotor testing rearing 23.9 1 1 5.9 0.00 1.0e+00 NA
Light reinforcement 1 84.1 1 1 5.9 0.00 1.0e+00 NA
Reaction time num false alarms 90.1 1 1 5.9 0.00 1.0e+00 NA
Reaction time num false alarms AUC 128.2 1 1 5.9 0.00 1.0e+00 NA
Reaction time trials on left 10.3 1 0 0.0 0.00 1.0e+00 NA
Reaction time mean 62.5 1 1 5.9 0.00 1.0e+00 NA
Reaction time mean AUC 89.1 1 1 5.9 0.00 1.0e+00 NA
Median of all reaction times 80.2 1 1 5.9 0.00 1.0e+00 NA
Reaction time false alarm rate 104.2 1 1 5.9 0.00 1.0e+00 NA
Reaction time premature initiation rate 47.3 1 1 5.9 0.00 1.0e+00 NA
Reaction time premature initiations 49.8 1 1 5.9 0.00 1.0e+00 NA
Std. dev. reaction times 27.0 1 1 5.9 0.00 1.0e+00 NA
Reaction time trials completed 10.3 1 0 0.0 0.00 1.0e+00 NA
Reaction time trials AUC 15.6 1 0 0.0 0.00 1.0e+00 NA
Social responses 108.6 1 1 5.9 0.00 1.0e+00 NA
Conditioned locomotion 14.7 1 0 0.0 0.00 1.0e+00 Epha6
Cocaine response after cond. corrected 135.7 1 1 5.9 0.00 1.0e+00 NA
Cocaine response after cond. not corrected 176.6 1 1 5.9 0.00 1.0e+00 NA
Cocaine response before conditioning 28.6 1 1 5.9 0.00 1.0e+00 NA
Saline control response 50.6 1 1 5.9 0.00 1.0e+00 NA
Condit. Reinf. active minus inactive responses 46.4 1 1 5.9 0.00 1.0e+00 NA
Condit. Reinf. active-inactive response ratio 68.7 1 1 5.9 0.00 1.0e+00 NA
Condit. Reinf. active responses 11.1 1 0 0.0 0.00 1.0e+00 NA
Condit. Reinf. inactive responses 20.6 1 0 0.0 0.00 1.0e+00 NA
Pavlov. Cond. lever latency 60.5 1 1 5.9 0.00 1.0e+00 NA
Pavlov. Cond. magazine entry latency 173.4 1 1 5.9 0.00 1.0e+00 NA
Pavlov. Cond. change in total contacts 216.7 1 1 5.9 0.00 1.0e+00 NA
Pavlov. Cond. index score 102.2 1 1 5.9 0.00 1.0e+00 NA
Pavlov. Cond. latency score 110.3 1 1 5.9 0.00 1.0e+00 NA
Pavlov. Cond. lever contacts 29.4 1 1 5.9 0.00 1.0e+00 NA
Pavlov. Cond. magazine entry number 244.9 1 1 5.9 0.00 1.0e+00 NA
Pavlov. Cond. intertrial magazine entries 106.2 1 1 5.9 0.00 1.0e+00 NA
Pavlov. Cond. lever-magazine prob. diff. 90.6 1 1 5.9 0.00 1.0e+00 NA
Pavlov. Cond. response bias 51.3 1 1 5.9 0.00 1.0e+00 NA
Conditioned reinforcement - actives 20.3 2 0 0.0 0.00 1.0e+00 Epha6 NA
Conditioned reinforcement - inactives 27.0 1 1 5.9 0.00 1.0e+00 Epha6
Intermittent access intake day 1-15 change 104.0 1 1 5.9 0.00 1.0e+00 NA
Intermittent access intake escalation 141.1 1 1 5.9 0.00 1.0e+00 NA
Intermittent access intake escalation 2 42.5 1 1 5.9 0.00 1.0e+00 NA
Intermitt. access day 1 inactive lever presses 30.6 1 1 5.9 0.00 1.0e+00 NA
Intermittent access day 1 total infusions 52.9 1 1 5.9 0.00 1.0e+00 NA
Intermittent access day 15 total infusions 13.7 1 0 0.0 0.00 1.0e+00 Epha6
Intermittent access terminal intake (last 3 days) 19.4 1 0 0.0 0.00 1.0e+00 Epha6
Intermittent access total infusions 17.6 1 0 0.0 0.00 1.0e+00 Epha6
Intermittent access day 1 locomotion 27.1 1 1 5.9 0.00 1.0e+00 NA
Cocaine induced anxiety 15.4 1 0 0.0 0.00 1.0e+00 Epha6
Post-drug Anxiety 20.6 1 0 0.0 0.00 1.0e+00 NA
Baseline Anxiety 18.8 1 0 0.0 0.00 1.0e+00 Epha6
Lifetime Intake 31.6 1 1 5.9 0.00 1.0e+00 Epha6
Progressive ratio test 1 active lever presses 25.4 1 1 5.9 0.00 1.0e+00 Epha6
Progressive ratio test 1 breakpoint 30.1 1 1 5.9 0.00 1.0e+00 Epha6
Progressive ratio test 2 active lever presses 31.2 1 1 5.9 0.00 1.0e+00 Epha6
Progressive ratio test 2 breakpoint 36.6 2 2 11.8 0.00 1.0e+00 Epha6 NA
Progressive ratio test 2 inactive lever presses 29.3 1 1 5.9 0.00 1.0e+00 Epha6
Total sessions with >9 infusions 15.7 1 0 0.0 0.00 1.0e+00 Epha6
Short access day 1 total infusions 37.1 1 1 5.9 0.00 1.0e+00 Epha6
Short access day 10 total infusions 24.0 1 1 5.9 0.00 1.0e+00 NA
Short access total infusions 40.4 1 1 5.9 0.00 1.0e+00 Epha6
Short access day 1 locomotion 17.2 1 0 0.0 0.00 1.0e+00 NA
Compulsive drug intake 45.4 1 1 5.9 0.00 1.0e+00 NA
One hour access (0.3 mA shock) 33.5 1 1 5.9 0.00 1.0e+00 Epha6
One hour access (shock baseline) 19.6 1 0 0.0 0.00 1.0e+00 Epha6
Context. condit. distance diff. score 240.2 1 1 5.9 0.00 1.0e+00 NA
Locomotion velocity, session 1 190.8 1 1 5.9 0.00 1.0e+00 NA
Locomotion distance, session 1 310.5 2 1 5.9 0.00 1.0e+00 Epha6 NA
Locomotion velocity, session 2 139.6 1 1 5.9 0.00 1.0e+00 NA
Locomotion distance, session 2 639.8 2 1 5.9 0.00 1.0e+00 Kif16b NA
Locomotion velocity, session 3 178.9 1 1 5.9 0.00 1.0e+00 NA
Locomotion distance, session 3 117.5 1 1 5.9 0.00 1.0e+00 NA
Stereotopy head waving duration, day 3 33.2 1 1 5.9 0.00 1.0e+00 NA
Locomotion velocity, session 7 98.9 1 1 5.9 0.00 1.0e+00 NA
Locomotion distance, session 7 18.8 2 1 5.9 0.00 1.0e+00 Epha6 NA
Stereotopy head waving bouts, day 7 68.4 1 1 5.9 0.00 1.0e+00 NA
Stereotopy head waving duration, day 7 102.2 1 1 5.9 0.00 1.0e+00 NA
Locomotion distance, session 8 171.7 1 1 5.9 0.00 1.0e+00 NA
Degree of sensitization distance 198.5 1 1 5.9 0.00 1.0e+00 NA
Degree of sensitization stereotypy 37.5 1 1 5.9 0.00 1.0e+00 NA
Condit. Reinf. active-inactive response ratio 107.3 1 1 5.9 0.00 1.0e+00 NA
Condit. Reinf. active responses 20.0 1 0 0.0 0.00 1.0e+00 NA
Condit. Reinf. inactive responses 17.2 1 0 0.0 0.00 1.0e+00 NA
Incentive salience index mean 15.6 1 0 0.0 0.00 1.0e+00 NA
Condit. Reinf. lever presses 23.0 2 1 5.9 0.00 1.0e+00 Epha6 NA
Time in familiar zone, hab. session 1 16.4 1 0 0.0 0.00 1.0e+00 NA
Time in novel zone, hab. session 1 17.4 1 0 0.0 0.00 1.0e+00 NA
Total zone transitions, hab. session 1 673.8 1 1 5.9 0.00 1.0e+00 NA
Total locomotion distance, hab. session 1 279.4 1 1 5.9 0.00 1.0e+00 NA
Locomotion velocity, hab. session 1 349.5 1 1 5.9 0.00 1.0e+00 NA
Time in familiar zone, hab. session 2 36.2 2 2 11.8 0.00 1.0e+00 Epha6 NA
Time in novel zone, hab. session 2 36.3 2 2 11.8 0.00 1.0e+00 Epha6 NA
Total zone transitions, hab. session 2 421.2 1 1 5.9 0.00 1.0e+00 NA
Total locomotion distance, hab. session 2 214.3 1 1 5.9 0.00 1.0e+00 NA
Locomotion velocity, hab. session 2 225.0 1 1 5.9 0.00 1.0e+00 NA
Total zone transitions, NPP test 376.1 1 1 5.9 0.00 1.0e+00 NA
Total locomotion distance, NPP test 269.3 1 1 5.9 0.00 1.0e+00 NA
Locomotion velocity, NPP test 317.8 1 1 5.9 0.00 1.0e+00 NA
Pavlov. Cond. lever latency 19.5 1 0 0.0 0.00 1.0e+00 Epha6
Pavlov. Cond. magazine entry latency 52.9 2 2 11.8 0.00 1.0e+00 Epha6 NA
Pavlov. Cond. change in total contacts 40.1 1 1 5.9 0.00 1.0e+00 NA
Pavlov. Cond. index score 33.5 2 2 11.8 0.00 1.0e+00 Epha6 NA
Pavlov. Cond. latency score 20.5 2 1 5.9 0.00 1.0e+00 Epha6 NA
Pavlov. Cond. lever contacts 19.0 2 1 5.9 0.00 1.0e+00 Epha6 NA
Pavlov. Cond. magazine entry number 38.2 2 1 5.9 0.00 1.0e+00 Epha6 NA
Pavlov. Cond. lever-magazine prob. diff. 44.7 2 2 11.8 0.00 1.0e+00 Epha6 NA
Pavlov. Cond. response bias 33.9 2 2 11.8 0.00 1.0e+00 Epha6 NA
Bone: apparent density 31.2 1 1 5.9 0.00 1.0e+00 NA
Bone surface 41.3 1 1 5.9 0.00 1.0e+00 NA
Bone volume 14.1 4 1 5.9 0.46 2.5e-01 Rab11fip2 Cacul1 Sfxn4 NA
Bone: cortical apparent density 10.8 2 0 0.0 -1.00 1.4e-03 Cacul1 Zfp950
Bone: cortical area 13.7 13 0 0.0 1.00 1.7e-41 Rab11fip2 Prlhr Cacul1 Dennd10 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 Casp7 NA NA NA
Bone: cortical porosity 188.5 1 1 5.9 0.00 1.0e+00 NA
Bone: cortical porosity 155.8 1 1 5.9 0.00 1.0e+00 NA
Bone: cortical thickness 9.6 11 0 0.0 0.99 1.4e-16 Rab11fip2 Cacul1 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 NA NA NA NA
Bone: cortical thickness 14.2 3 0 0.0 -0.27 7.3e-01 Prdx3 Epha6 NA
Bone: cortical tissue density 11.4 4 0 0.0 -1.00 4.8e-09 Cacul1 Nanos1 Zfp950 Sfxn4
Bone: elastic displacement 28.2 1 1 5.9 0.00 1.0e+00 NA
Bone: endosteal estimation 18.4 1 1 5.9 0.00 1.0e+00 NA
Bone: final force 11.2 10 1 5.9 0.80 1.4e-07 Rab11fip2 Cacul1 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 NA NA NA
Bone: final moment 11.2 11 1 5.9 0.84 3.2e-09 Rab11fip2 Cacul1 Dennd10 Prdx3 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 NA NA
Bone: marrow area 15.3 1 1 5.9 0.00 1.0e+00 NA
Bone: maximum diameter 8.7 5 0 0.0 0.99 1.7e-11 Cacul1 Nanos1 Zfp950 Sfxn4 Casp7
Bone: maximum force 12.3 8 1 5.9 0.72 7.3e-04 Rab11fip2 Cacul1 Grk5 Nanos1 Zfp950 Sfxn4 NA NA
Bone: maximum moment 10.9 9 1 5.9 0.81 4.6e-06 Rab11fip2 Prlhr Cacul1 Grk5 Nanos1 Zfp950 Sfxn4 NA NA
Bone: minimum diameter 14.2 7 1 5.9 0.53 6.2e-02 Cacul1 Nanos1 Zfp950 Ces2c Sfxn4 NA NA
Bone: periosteal estimation 8.9 13 0 0.0 0.94 3.1e-19 Rab11fip2 Prlhr Cacul1 Dennd10 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 Casp7 NA NA NA
Bone: periosteal perimeter 11.1 11 0 0.0 0.94 3.8e-16 Rab11fip2 Cacul1 Dennd10 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 Casp7 NA NA
Bone: post-yield work 124.3 1 1 5.9 0.00 1.0e+00 NA
Bone: stiffness 136.8 1 1 5.9 0.00 1.0e+00 NA
Bone: tissue strength 136.0 1 1 5.9 0.00 1.0e+00 NA
Bone: trabecular number 64.1 1 1 5.9 0.00 1.0e+00 NA
Bone: trabecular thickness 13.3 11 0 0.0 0.93 4.7e-14 Rab11fip2 Prlhr Cacul1 Dennd10 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 NA NA
Bone: trabecular tissue density 66.6 1 1 5.9 0.00 1.0e+00 NA
Delta time in open arm before/after self-admin 40.2 1 1 5.9 0.00 1.0e+00 NA
Time in closed arm before self-admin 78.0 1 1 5.9 0.00 1.0e+00 NA
Time in closed arm after self-admin 40.2 1 1 5.9 0.00 1.0e+00 NA
Time in open arm after self-admin 31.3 1 1 5.9 0.00 1.0e+00 NA
Delta time to tail flick, test, before/after SA 20.0 1 0 0.0 0.00 1.0e+00 NA
Time >=10cm from walls, locomotor time 1 19.5 1 0 0.0 0.00 1.0e+00 NA
Time >=10cm from walls, locomotor time 2 27.2 1 1 5.9 0.00 1.0e+00 NA
Distance moved, locomotor task time 2 13.1 1 0 0.0 0.00 1.0e+00 NA
Weight adjusted by age 25.0 1 1 5.9 0.00 1.0e+00 NA
Seeking ratio, delayed vs. immediate footshock 12.3 1 0 0.0 0.00 1.0e+00 Ces2c
Locomotion in novel chamber post-restriction 15.3 1 0 0.0 0.00 1.0e+00 Epha6
Food seeking constrained by brief footshock 12.4 2 0 0.0 -1.00 7.1e-04 Dnajc27 Efr3b
Run reversals in cocaine runway, males 39.3 1 1 5.9 0.00 1.0e+00 NA
Latency to leave start box in cocaine runway 18.8 1 0 0.0 0.00 1.0e+00 NA
Cd content in liver 239.3 1 1 5.9 0.00 1.0e+00 NA
Co content in liver 143.3 1 1 5.9 0.00 1.0e+00 NA
K content in liver 87.3 1 1 5.9 0.00 1.0e+00 NA
Mn content in liver 207.1 1 1 5.9 0.00 1.0e+00 NA
Rb content in liver 31.4 1 1 5.9 0.00 1.0e+00 NA
Se content in liver 30.1 2 1 5.9 0.00 1.0e+00 Epha6 NA
Zn content in liver 46.0 1 1 5.9 0.00 1.0e+00 NA

chisq ratio: Average Chi2 statistic for the selected genes in the secondary trait, divided by the average statistic for all genes in the secondary trait. # genes+: Shared significant genes at Bonferroni correction. # genes++: Shared significant genes at transcriptome-wide significance. % genes++: Number of [++] genes as a percentage of primary trait’s total joint genes. corr: Correlation of effect sizes across the [+] genes.

Associations by panel

tissue modality # hits % hits/tests avg chisq
Adipose alternative polyA 2 0.094 1.9
Adipose alternative TSS 2 0.124 1.8
Adipose gene expression 15 0.181 1.9
Adipose isoform ratio 3 0.106 1.9
Adipose intron excision ratio 0 0.000 1.8
Adipose mRNA stability 10 0.290 1.9
BLA alternative polyA 2 0.167 1.8
BLA alternative TSS 0 0.000 1.9
BLA gene expression 16 0.264 2.0
BLA isoform ratio 3 0.170 1.9
BLA intron excision ratio 4 0.134 2.0
BLA mRNA stability 4 0.198 1.9
Brain alternative polyA 2 0.100 1.8
Brain alternative TSS 2 0.116 1.9
Brain gene expression 19 0.210 2.0
Brain isoform ratio 6 0.190 2.1
Brain intron excision ratio 5 0.092 2.0
Brain mRNA stability 7 0.160 1.9
Eye alternative polyA 0 0.000 2.0
Eye alternative TSS 1 0.417 2.1
Eye gene expression 5 0.445 2.0
Eye isoform ratio 0 0.000 1.8
Eye intron excision ratio 1 0.163 1.9
Eye mRNA stability 0 0.000 1.9
IL alternative polyA 0 0.000 1.6
IL alternative TSS 0 0.000 1.8
IL gene expression 8 0.219 2.0
IL isoform ratio 0 0.000 1.9
IL intron excision ratio 0 0.000 2.1
IL mRNA stability 2 0.180 2.0
LHb alternative polyA 0 0.000 1.6
LHb alternative TSS 0 0.000 2.1
LHb gene expression 6 0.187 2.0
LHb isoform ratio 3 0.398 1.9
LHb intron excision ratio 0 0.000 1.9
LHb mRNA stability 3 0.290 2.0
Liver alternative polyA 7 0.466 1.8
Liver alternative TSS 0 0.000 1.9
Liver gene expression 15 0.209 2.0
Liver isoform ratio 8 0.335 2.1
Liver intron excision ratio 7 0.160 2.0
Liver mRNA stability 4 0.163 2.0
NAcc alternative polyA 0 0.000 1.7
NAcc alternative TSS 0 0.000 1.8
NAcc gene expression 13 0.206 2.0
NAcc isoform ratio 3 0.159 2.0
NAcc intron excision ratio 2 0.065 2.1
NAcc mRNA stability 2 0.088 1.9
OFC alternative polyA 2 0.342 1.8
OFC alternative TSS 0 0.000 1.9
OFC gene expression 6 0.162 2.0
OFC isoform ratio 0 0.000 1.9
OFC intron excision ratio 1 0.100 2.2
OFC mRNA stability 2 0.185 2.0
PL alternative polyA 0 0.000 1.7
PL alternative TSS 2 0.170 2.0
PL gene expression 19 0.257 2.0
PL isoform ratio 2 0.091 2.0
PL intron excision ratio 5 0.140 2.0
PL mRNA stability 5 0.171 1.9

avg chisq: Average Chi2 (squared Z-score) across all models in this panel for this trait.