Parametrial fat weight

Tags: Physiology · Weight

Project: dissection

7 loci · 24 genes with independent associations · 536 total associated genes

Significant Loci

# Chr Start pos End pos # assoc genes # joint models Best TWAS P Best GWAS P Cond GWAS P Joint genes
1 chr1 263352174 270504995 119 6 7.15e-28 9.15e-28 1.00e+00 Atrnl1 Cacul1 Eno4 LOC134485255 LOC134485267 Sfxn4
2 chr3 149420994 153353421 109 5 6.76e-19 1.59e-18 1.00e+00 LOC120101719 Pcsk2 Rbbp9 Rrbp1 Snrpb2
3 chr6 28764558 34886571 293 8 1.09e-18 1.48e-18 1.00e+00 Dnajc27 Efr3b Fkbp1b Hadhb Itsn2 Klhl29 Tmem214 Yipf4l1
4 chr9 83390749 85073307 2 2 0.00e+00 2.50e-02 1.00e+00 Gmppa Retreg2
5 chr10 56631856 58902949 11 1 5.80e-09 1.11e-06 4.49e-01 4933427D14Rikl
6 chr13 49989548 51387195 1 1 1.59e-07 1.01e-07 7.86e-02 LOC102547588
7 chr15 21952499 23260563 1 1 1.77e-07 1.77e-07 2.84e-01 Cgrrf1

Pleiotropic Associations

Trait Chi2 ratio # genes+ # genes++ % genes++ Corr Corr P Genes
BMI with tail 19.84 74 70 291.7 0.64 8.19e-64 Ablim1 Acsl5 Afap1l2 Atrnl1 Banf2 Cacul1 Casp7 Ccdc186 Ces2c Dclre1a Dennd10 Dstn Dtd1 Dzank1 Emx2os Eno4 Fam204a Fhip2a Gfra1 Gpam Grk5 Gucy2g Habp2 Hspa12a Kat14 Kif16b LOC102547573 LOC102550304 LOC102551125 LOC102553657 LOC102556644 LOC103691380 LOC120097692 LOC120100061 LOC120100065 LOC120100068 LOC120101717 LOC120101719 LOC134485255 LOC134485257 LOC134485258 LOC134485266 LOC134485267 LOC134485268 LOC134486165 LOC134486454 LOC134486455 LOC134486456 Nanos1 Nhlrc2 Nrap Otor Pcsk2 Plekhs1 Pnlip Polr3f Prdx3 Prlhr Rab11fip2 Rbbp9 Retreg2 Rrbp1 Scp2d1 Sec23b Sfxn4 Smim26 Snrpb2 Tcf7l2 Tectb Trub1 Vti1a Zdhhc6 Zfp133 Zfp933l1
BMI without tail 301.68 68 41 170.8 0.37 1.59e-17 Ablim1 Acsl5 Afap1l2 Atrnl1 Banf2 Cacul1 Casp7 Ccdc186 Ces2c Dclre1a Dennd10 Dstn Dtd1 Dzank1 Emx2os Eno4 Fam204a Fhip2a Gfra1 Gpam Grk5 Gucy2g Habp2 Hspa12a Kat14 Kif16b LOC102547573 LOC102550304 LOC102551125 LOC120097692 LOC120100061 LOC120100065 LOC120100068 LOC120101717 LOC120101719 LOC134485255 LOC134485257 LOC134485258 LOC134485266 LOC134485267 LOC134486165 LOC134486454 LOC134486455 LOC134486456 Nanos1 Nhlrc2 Nrap Otor Pcsk2 Plekhs1 Polr3f Prdx3 Prlhr Rab11fip2 Rbbp9 Retreg2 Rrbp1 Scp2d1 Sec23b Sfxn4 Smim26 Snrpb2 Tcf7l2 Trub1 Vti1a Zdhhc6 Zfp133 Zfp933l1
Body weight 13.17 74 72 300 0.97 0.00e+00 Ablim1 Acsl5 Afap1l2 Atrnl1 Banf2 Cacul1 Casp7 Ccdc186 Ces2c Dclre1a Dennd10 Dstn Dtd1 Dzank1 Emx2os Eno4 Fam204a Fhip2a Gfra1 Gpam Grk5 Gucy2g Habp2 Hspa12a Kat14 Kif16b LOC102547573 LOC102550304 LOC102551125 LOC102553657 LOC102556644 LOC103691380 LOC120097692 LOC120100061 LOC120100065 LOC120100068 LOC120101717 LOC120101719 LOC134485255 LOC134485257 LOC134485258 LOC134485266 LOC134485267 LOC134485268 LOC134486165 LOC134486454 LOC134486455 LOC134486456 Nanos1 Nhlrc2 Nrap Otor Pcsk2 Plekhs1 Pnlip Polr3f Prdx3 Prlhr Rab11fip2 Rbbp9 Retreg2 Rrbp1 Scp2d1 Sec23b Sfxn4 Smim26 Snrpb2 Tcf7l2 Tectb Trub1 Vti1a Zdhhc6 Zfp133 Zfp933l1
Epididymis fat weight 101.88 148 145 604.2 0.46 4.79e-63 4933427D14Rikl Abhd1 Ablim1 Acsl5 Adcy3 Afap1l2 Agbl5 Asxl2 Atad2b Atraid Atrnl1 Banf2 Cacul1 Cad Casp7 Ccdc186 Cenpo Ces2c Cgref1 Cimip2c Clip4 Cyb5d2 Dclre1a Dennd10 Dnajc27 Dnmt3a Dpysl5 Drc1 Dstn Dtd1 Dtnb Dzank1 Efr3b Eif2b4 Emx2os Eno4 Fam204a Fam228b Fhip2a Fkbp1b Fndc4 Fosl2 Garem2 Gfra1 Gpam Gpn1 Grk5 Gtf3c2 Gucy2g Habp2 Hadha Hadhb Hspa12a Ift172 Itgae Itsn2 Kat14 Kcnk3 Khk Kif16b Kif3c Klhl29 LOC102547573 LOC102548914 LOC102550304 LOC102551125 LOC102553657 LOC102556644 LOC103691380 LOC103692581 LOC120097692 LOC120100061 LOC120100065 LOC120100068 LOC120101717 LOC120101719 LOC120103488 LOC120103494 LOC120103495 LOC120103497 LOC120103502 LOC134479112 LOC134479333 LOC134479335 LOC134485255 LOC134485257 LOC134485258 LOC134485266 LOC134485267 LOC134485268 LOC134486165 LOC134486454 LOC134486455 LOC134486456 Mapre3 Mpv17 Nanos1 Ncoa1 Nhlrc2 Nrap Nrbp1 Ost4 Otof Otor Pcare Pcsk2 Pfn4 Plb1 Plekhs1 Pnlip Polr3f Ppp1cb Prdx3 Preb Prlhr Rab10 Rab11fip2 Rbbp9 Rbks Retreg2 Rrbp1 Scp2d1 Sec23b Sf3b6 Sfxn4 Slc30a3 Slc35f6 Slc4a1ap Slc5a6 Smim26 Smtnl2 Snrpb2 Snx17 Spdya Tcf7l2 Tectb Tekt1 Tmem214 Togaram2 Trim54 Trub1 Ubxn2a Vti1a Yipf4l1 Zdhhc6 Zfp133 Zfp513 Zfp933l1
Glucose 1188.51 2 1 4.2 0 1.00e+00 Ces2c Retreg2
Heart weight 296.4 12 4 16.7 -0.31 3.39e-02 Cacul1 Ces2c Dennd10 Grk5 LOC120100068 LOC134485267 Nanos1 Prlhr Rab11fip2 Retreg2 Sfxn4 Zfp933l1
Left kidney weight 1940.31 18 14 58.3 -0.43 1.55e-04 Cacul1 Casp7 Ces2c Dennd10 Emx2os Gpam Grk5 LOC120100068 LOC134485266 LOC134485267 Nanos1 Prdx3 Prlhr Rab11fip2 Retreg2 Sfxn4 Vti1a Zfp933l1
Right kidney weight 1129.48 27 15 62.5 -0.38 8.36e-05 Ablim1 Acsl5 Cacul1 Casp7 Ces2c Dennd10 Emx2os Gpam Grk5 Habp2 LOC120100068 LOC134485255 LOC134485266 LOC134485267 Nanos1 Nhlrc2 Nrap Plekhs1 Prdx3 Prlhr Rab11fip2 Retreg2 Sfxn4 Tcf7l2 Vti1a Zdhhc6 Zfp933l1
Tail length 92117.69 1 1 4.2 0 1.00e+00 Retreg2
Length with tail 174.8 8 1 4.2 0.77 5.00e-08 Kif16b LOC120101719 Otor Pcsk2 Retreg2 Rrbp1 Sec23b Snrpb2
Length without tail 1473.44 27 2 8.3 -0.46 7.18e-06 Acsl5 Cacul1 Casp7 Dclre1a Gpam Grk5 Gucy2g Habp2 Kif16b LOC102553657 LOC120100061 LOC120101719 LOC134485255 LOC134486165 Nanos1 Nhlrc2 Nrap Otor Prlhr Rab11fip2 Retreg2 Sfxn4 Snrpb2 Tcf7l2 Tectb Vti1a Zdhhc6
Liver weight, left 286.48 16 6 25 -0.32 2.13e-02 Cacul1 Casp7 Ces2c Dennd10 Emx2os Grk5 LOC120100068 LOC134485266 LOC134485267 Nanos1 Prdx3 Prlhr Rab11fip2 Retreg2 Sfxn4 Zfp933l1
Liver weight, right 12.1 42 1 4.2 0.6 9.06e-15 Abhd1 Acsl5 Atraid Cacul1 Cad Casp7 Clip4 Dpysl5 Eif2b4 Fndc4 Fosl2 Gpam Gpn1 Gtf3c2 Gucy2g Ift172 Khk LOC102548914 LOC120103488 LOC134485255 Mpv17 Nrbp1 Otof Pcare Plb1 Ppp1cb Preb Prlhr Rab11fip2 Rbks Retreg2 Sfxn4 Slc30a3 Slc4a1ap Slc5a6 Snx17 Spdya Tcf7l2 Togaram2 Trim54 Vti1a Zdhhc6
Retroperitoneal fat weight 38.52 144 143 595.8 0.88 0.00e+00 Abhd1 Ablim1 Acsl5 Adcy3 Afap1l2 Agbl5 Asxl2 Atad2b Atraid Atrnl1 Banf2 Cacul1 Cad Casp7 Ccdc186 Cenpo Ces2c Cgref1 Cgrrf1 Cimip2c Clip4 Dclre1a Dennd10 Dnajc27 Dnmt3a Dpysl5 Drc1 Dstn Dtd1 Dtnb Dzank1 Efr3b Eif2b4 Emx2os Eno4 Fam204a Fam228b Fhip2a Fkbp1b Fndc4 Fosl2 Garem2 Gfra1 Gpam Gpn1 Grk5 Gtf3c2 Gucy2g Habp2 Hadha Hadhb Hspa12a Ift172 Itsn2 Kat14 Kcnk3 Khk Kif16b Kif3c Klhl29 LOC102547573 LOC102548914 LOC102550304 LOC102551125 LOC102553657 LOC102556644 LOC103691380 LOC103692581 LOC120097692 LOC120100061 LOC120100065 LOC120100068 LOC120101717 LOC120101719 LOC120103488 LOC120103494 LOC120103495 LOC120103497 LOC120103502 LOC134479112 LOC134479333 LOC134479335 LOC134485255 LOC134485257 LOC134485258 LOC134485266 LOC134485267 LOC134485268 LOC134486165 LOC134486454 LOC134486455 LOC134486456 Mapre3 Mpv17 Nanos1 Ncoa1 Nhlrc2 Nrap Nrbp1 Ost4 Otof Otor Pcare Pcsk2 Pfn4 Plb1 Plekhs1 Pnlip Polr3f Ppp1cb Prdx3 Preb Prlhr Rab10 Rab11fip2 Rbbp9 Rbks Retreg2 Rrbp1 Scp2d1 Sec23b Sf3b6 Sfxn4 Slc30a3 Slc35f6 Slc4a1ap Slc5a6 Smim26 Snrpb2 Snx17 Spdya Tcf7l2 Tectb Tmem214 Togaram2 Trim54 Trub1 Ubxn2a Vti1a Yipf4l1 Zdhhc6 Zfp133 Zfp513 Zfp933l1
Intraocular pressure 40071.91 1 1 4.2 0 1.00e+00 Retreg2
Extensor digitorum longus weight 35.86 35 1 4.2 0.17 3.80e-02 Abhd1 Agbl5 Atraid Cad Cgref1 Clip4 Dpysl5 Eif2b4 Fndc4 Fosl2 Gpn1 Gtf3c2 Itgae Khk LOC102548914 LOC120100068 LOC120103488 Mapre3 Mpv17 Nrbp1 Ost4 Otof Pcare Plb1 Ppp1cb Preb Rbks Retreg2 Slc30a3 Slc35f6 Slc5a6 Snx17 Spdya Togaram2 Trim54
Soleus weight 13.88 13 1 4.2 0.75 2.04e-03 Ablim1 Acsl5 Clip4 Eno4 Fosl2 Gucy2g LOC134485258 LOC134485266 Pcare Ppp1cb Rab11fip2 Retreg2 Togaram2
Tibialis anterior weight 1631.05 3 1 4.2 0 1.00e+00 4933427D14Rikl Itgae Retreg2
Tibia length 224.56 5 1 4.2 0.93 4.56e-07 Kif16b LOC134486165 Otor Retreg2 Snrpb2
Number of licking bursts 157119.65 1 1 4.2 0 1.00e+00 Retreg2
Food consumed during 24 hour testing period 106196.53 1 1 4.2 0 1.00e+00 Retreg2
Times rat made contact with spout 305.36 1 1 4.2 0 1.00e+00 Retreg2
Mean time between licks in bursts 199507.71 1 1 4.2 0 1.00e+00 Retreg2
Mean num. licks in bursts 142600.29 1 1 4.2 0 1.00e+00 Retreg2
Std. dev. time between licks in bursts 94042.02 1 1 4.2 0 1.00e+00 Retreg2
Water consumed over 24 hours 103408.69 1 1 4.2 0 1.00e+00 Retreg2
Patch foraging indifference point 0 sec 115003.89 1 1 4.2 0 1.00e+00 Retreg2
Patch foraging indifference point AUC 133114.6 1 1 4.2 0 1.00e+00 Retreg2
Indifference point function ln k 142006.4 1 1 4.2 0 1.00e+00 Retreg2
Indifference point function log k 142006.4 1 1 4.2 0 1.00e+00 Retreg2
Patch foraging total patch changes 0 sec 60135.1 2 1 4.2 0 1.00e+00 Retreg2 Sfxn4
Patch foraging total patch changes 12 sec 10848.8 1 1 4.2 0 1.00e+00 Retreg2
Patch foraging total patch changes 18 sec 117768.16 1 1 4.2 0 1.00e+00 Retreg2
Patch foraging total patch changes 24 sec 167090.22 1 1 4.2 0 1.00e+00 Retreg2
Patch foraging total patch changes 6 sec 16324.9 2 1 4.2 0 1.00e+00 LOC134485258 Retreg2
Patch foraging time to switch 0 sec 156618.53 1 1 4.2 0 1.00e+00 Retreg2
Patch foraging water rate 0 sec 148807.58 1 1 4.2 0 1.00e+00 Retreg2
Patch foraging water rate 12 sec 161858.08 1 1 4.2 0 1.00e+00 Retreg2
Patch foraging water rate 18 sec 6082.71 8 1 4.2 -0.83 3.33e-05 Dtd1 Dzank1 Kat14 Rbbp9 Retreg2 Scp2d1 Sec23b Smim26
Patch foraging water rate 24 sec 4691.77 1 1 4.2 0 1.00e+00 Retreg2
Patch foraging water rate 6 sec 3954.86 1 1 4.2 0 1.00e+00 Retreg2
Locomotor activity 12.34 1 0 0 0 1.00e+00 Retreg2
Locomotor testing distance 89448.55 1 1 4.2 0 1.00e+00 Retreg2
Locomotor testing rearing 152414.81 1 1 4.2 0 1.00e+00 Retreg2
Light reinforcement 1 155242.72 1 1 4.2 0 1.00e+00 Retreg2
Light reinforcement 2 107899.08 1 1 4.2 0 1.00e+00 Retreg2
Reaction time number correct 153465.22 1 1 4.2 0 1.00e+00 Retreg2
Reaction time mean minus median 205810.62 1 1 4.2 0 1.00e+00 Retreg2
Reaction time mean minus median AUC 208396.98 1 1 4.2 0 1.00e+00 Retreg2
Reaction time num false alarms 57075.22 1 1 4.2 0 1.00e+00 Retreg2
Reaction time num false alarms AUC 106496.51 1 1 4.2 0 1.00e+00 Retreg2
Reaction time trials correct on left 153465.22 1 1 4.2 0 1.00e+00 Retreg2
Reaction time trials on left 149991.58 1 1 4.2 0 1.00e+00 Retreg2
Reaction time mean 94380.53 1 1 4.2 0 1.00e+00 Retreg2
Reaction time mean AUC 113341.21 1 1 4.2 0 1.00e+00 Retreg2
Median of all reaction times 31417.12 1 1 4.2 0 1.00e+00 Retreg2
Reaction time omissions 34267.91 1 1 4.2 0 1.00e+00 Retreg2
Reaction time false alarm rate 891.26 1 1 4.2 0 1.00e+00 Retreg2
Reaction time premature initiation rate 36877.02 1 1 4.2 0 1.00e+00 Retreg2
Reaction time premature initiations 138718.63 1 1 4.2 0 1.00e+00 Retreg2
Std. dev. reaction times 149487.71 1 1 4.2 0 1.00e+00 Retreg2
Reaction time trials completed 149991.58 1 1 4.2 0 1.00e+00 Retreg2
Reaction time trials AUC 151696.42 1 1 4.2 0 1.00e+00 Retreg2
Social response proportion 35302.65 1 1 4.2 0 1.00e+00 Retreg2
Social responses 5682.08 1 1 4.2 0 1.00e+00 Retreg2
Social time 44238.34 1 1 4.2 0 1.00e+00 Retreg2
Conditioned locomotion 6074.35 1 1 4.2 0 1.00e+00 Retreg2
Cocaine response after cond. corrected 65812.39 1 1 4.2 0 1.00e+00 Retreg2
Cocaine response after cond. not corrected 64247.35 1 1 4.2 0 1.00e+00 Retreg2
Cocaine response before conditioning 2800.41 1 1 4.2 0 1.00e+00 Retreg2
Saline control response 12962.78 1 1 4.2 0 1.00e+00 Retreg2
Condit. Reinf. active minus inactive responses 53410.48 1 1 4.2 0 1.00e+00 Retreg2
Condit. Reinf. active-inactive response ratio 91582.24 1 1 4.2 0 1.00e+00 Retreg2
Condit. Reinf. active responses 9691.24 1 1 4.2 0 1.00e+00 Retreg2
Condit. Reinf. inactive responses 42106.18 1 1 4.2 0 1.00e+00 Retreg2
Condit. Reinf. lever presses 15873.43 1 1 4.2 0 1.00e+00 Retreg2
Condit. Reinf. lever reinforcers received 2000.77 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. lever latency 10912.53 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. magazine entry latency 49418.79 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. change in total contacts 114781.94 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. index score 47988.08 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. latency score 58476.16 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. lever contacts 22069.78 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. magazine entry number 16773.11 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. intertrial magazine entries 104933.78 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. lever-magazine prob. diff. 44871.67 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. response bias 5169.79 1 1 4.2 0 1.00e+00 Retreg2
Conditioned reinforcement - actives 191492.54 1 1 4.2 0 1.00e+00 Retreg2
Conditioned reinforcement - inactives 155032.91 1 1 4.2 0 1.00e+00 Retreg2
Conditioned locomotion 41346.85 1 1 4.2 0 1.00e+00 Retreg2
Intermittent access intake day 1-15 change 210605.99 1 1 4.2 0 1.00e+00 Retreg2
Intermittent access intake escalation 209543.53 1 1 4.2 0 1.00e+00 Retreg2
Intermittent access intake escalation 2 107995.31 1 1 4.2 0 1.00e+00 Retreg2
Intermitt. access day 1 inactive lever presses 236542.72 1 1 4.2 0 1.00e+00 Retreg2
Intermitt. access day 15 inactive lever presses 208241.66 1 1 4.2 0 1.00e+00 Retreg2
Intermitt. access escalation Index 184996.65 1 1 4.2 0 1.00e+00 Retreg2
Intermittent access day 1 total infusions 155525.68 1 1 4.2 0 1.00e+00 Retreg2
Intermittent access day 15 total infusions 131485.34 1 1 4.2 0 1.00e+00 Retreg2
Intermittent access terminal intake (last 3 days) 83205.14 1 1 4.2 0 1.00e+00 Retreg2
Intermittent access total infusions 675.9 1 1 4.2 0 1.00e+00 Retreg2
Intermittent access day 1 locomotion 104459.41 1 1 4.2 0 1.00e+00 Retreg2
Intermittent access day 15 total locomotion 177836.92 1 1 4.2 0 1.00e+00 Retreg2
Intermittent access total locomotion 711.59 1 1 4.2 0 1.00e+00 Retreg2
Intermittent access standard deviation 201906.25 1 1 4.2 0 1.00e+00 Retreg2
Cocaine induced anxiety 160280.46 1 1 4.2 0 1.00e+00 Retreg2
Post-drug Anxiety 20460.83 1 1 4.2 0 1.00e+00 Retreg2
Baseline Anxiety 51741.5 2 1 4.2 0 1.00e+00 Gmppa Retreg2
Lifetime Intake 6830.03 1 1 4.2 0 1.00e+00 Retreg2
Incentive Sensitization - Responses 163579.25 1 1 4.2 0 1.00e+00 Retreg2
Incentive Sensitization - Breakpoint 142790.8 1 1 4.2 0 1.00e+00 Retreg2
Progressive ratio test 1 active lever presses 99872.69 1 1 4.2 0 1.00e+00 Retreg2
Progressive ratio test 1 breakpoint 96247.61 1 1 4.2 0 1.00e+00 Retreg2
Progressive ratio test 1 inactive lever presses 151100.07 1 1 4.2 0 1.00e+00 Retreg2
Progressive ratio test 2 active lever presses 57222.6 1 1 4.2 0 1.00e+00 Retreg2
Progressive ratio test 2 breakpoint 34975.96 1 1 4.2 0 1.00e+00 Retreg2
Progressive ratio test 2 inactive lever presses 164104.71 1 1 4.2 0 1.00e+00 Retreg2
Total sessions with >9 infusions 7953.9 1 1 4.2 0 1.00e+00 Retreg2
Short access day 1 total inactive lever presses 114392.27 1 1 4.2 0 1.00e+00 Retreg2
Short access day 10 total inactive lever presses 217140.65 1 1 4.2 0 1.00e+00 Retreg2
Short access day 1 total infusions 111479.43 1 1 4.2 0 1.00e+00 Retreg2
Short access day 10 total infusions 76293.54 1 1 4.2 0 1.00e+00 Retreg2
Short access total infusions 33946.03 1 1 4.2 0 1.00e+00 Retreg2
Short access day 1 locomotion 84055.65 1 1 4.2 0 1.00e+00 Retreg2
Short access day 10 total locomotion 181597.84 1 1 4.2 0 1.00e+00 Retreg2
Short access total locomotion 68266.59 1 1 4.2 0 1.00e+00 Retreg2
Compulsive drug intake 65439.45 1 1 4.2 0 1.00e+00 Retreg2
One hour access (0.3 mA shock) 9669.44 1 1 4.2 0 1.00e+00 Retreg2
One hour access (shock baseline) 140263.4 1 1 4.2 0 1.00e+00 Retreg2
Number of responses in last shaping day 51289.19 1 1 4.2 0 1.00e+00 Retreg2
Context. condit. distance diff. score 970.59 1 1 4.2 0 1.00e+00 Retreg2
Locomotion velocity, session 1 14615.25 1 1 4.2 0 1.00e+00 Retreg2
Locomotion distance, session 1 4416.18 1 1 4.2 0 1.00e+00 Retreg2
Locomotion velocity, session 2 9358 1 1 4.2 0 1.00e+00 Retreg2
Locomotion distance, session 2 2393.66 1 1 4.2 0 1.00e+00 Retreg2
Locomotion velocity, session 3 2332.53 1 1 4.2 0 1.00e+00 Retreg2
Locomotion distance, session 3 16615.78 1 1 4.2 0 1.00e+00 Retreg2
Stereotopy head waving bouts, day 3 5866.4 1 1 4.2 0 1.00e+00 Retreg2
Stereotopy head waving duration, day 3 12131.92 1 1 4.2 0 1.00e+00 Retreg2
Locomotion velocity, session 7 1310.17 1 1 4.2 0 1.00e+00 Retreg2
Locomotion distance, session 7 3744.54 1 1 4.2 0 1.00e+00 Retreg2
Stereotopy head waving bouts, day 7 10466.92 1 1 4.2 0 1.00e+00 Retreg2
Stereotopy head waving duration, day 7 8847.36 1 1 4.2 0 1.00e+00 Retreg2
Locomotion velocity, session 8 1892.98 1 1 4.2 0 1.00e+00 Retreg2
Locomotion distance, session 8 673.32 1 1 4.2 0 1.00e+00 Retreg2
Degree of sensitization distance 15309.16 1 1 4.2 0 1.00e+00 Retreg2
Degree of sensitization stereotypy 8496.38 1 1 4.2 0 1.00e+00 Retreg2
Condit. Reinf. active minus inactive responses 4120.78 1 1 4.2 0 1.00e+00 Retreg2
Condit. Reinf. active-inactive response ratio 1097.66 1 1 4.2 0 1.00e+00 Retreg2
Condit. Reinf. active responses 11664.93 1 1 4.2 0 1.00e+00 Retreg2
Condit. Reinf. inactive responses 19375.3 1 1 4.2 0 1.00e+00 Retreg2
Incentive salience index mean 14781.83 1 1 4.2 0 1.00e+00 Retreg2
Condit. Reinf. lever presses 21433.81 1 1 4.2 0 1.00e+00 Retreg2
Time in familiar zone, hab. session 1 41873.03 1 1 4.2 0 1.00e+00 Retreg2
Time in novel zone, hab. session 1 35522.88 1 1 4.2 0 1.00e+00 Retreg2
Total zone transitions, hab. session 1 1818.53 1 1 4.2 0 1.00e+00 Retreg2
Total locomotion distance, hab. session 1 1687 1 1 4.2 0 1.00e+00 Retreg2
Locomotion velocity, hab. session 1 1131.06 1 1 4.2 0 1.00e+00 Retreg2
Time in familiar zone, hab. session 2 23379.25 1 1 4.2 0 1.00e+00 Retreg2
Time in novel zone, hab. session 2 24924.95 1 1 4.2 0 1.00e+00 Retreg2
Total zone transitions, hab. session 2 280.53 1 1 4.2 0 1.00e+00 Retreg2
Total locomotion distance, hab. session 2 96.8 1 1 4.2 0 1.00e+00 Retreg2
Locomotion velocity, hab. session 2 145.53 1 1 4.2 0 1.00e+00 Retreg2
Novel to familiar place preference ratio 55508.81 1 1 4.2 0 1.00e+00 Retreg2
Novelty place preference 54383.96 1 1 4.2 0 1.00e+00 Retreg2
Time in novel zone, NPP test 40844.77 1 1 4.2 0 1.00e+00 Retreg2
Total zone transitions, NPP test 8230.03 1 1 4.2 0 1.00e+00 Retreg2
Total locomotion distance, NPP test 7114 1 1 4.2 0 1.00e+00 Retreg2
Locomotion velocity, NPP test 4041.22 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. lever latency 2195.61 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. change in total contacts 4539.35 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. index score 1769.33 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. latency score 1841.19 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. lever contacts 3029.77 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. magazine entry number 2162.19 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. intertrial magazine entries 524.02 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. lever-magazine prob. diff. 1940.27 1 1 4.2 0 1.00e+00 Retreg2
Pavlov. Cond. response bias 2606.99 1 1 4.2 0 1.00e+00 Retreg2
Bone: apparent density 22268.03 1 1 4.2 0 1.00e+00 Retreg2
Bone surface 25125.6 1 1 4.2 0 1.00e+00 Retreg2
Bone volume 33831.7 1 1 4.2 0 1.00e+00 Retreg2
Bone: connectivity density 7098.55 1 1 4.2 0 1.00e+00 Retreg2
Bone: cortical apparent density 45266.32 1 1 4.2 0 1.00e+00 Retreg2
Bone: cortical area 224.76 27 2 8.3 0.66 2.94e-12 Ablim1 Afap1l2 Cacul1 Casp7 Ces2c Dclre1a Dennd10 Fhip2a Grk5 Habp2 LOC102547573 LOC120100061 LOC120100065 LOC120100068 LOC134485255 LOC134485267 Nanos1 Nhlrc2 Nrap Plekhs1 Prlhr Rab11fip2 Retreg2 Sfxn4 Trub1 Vti1a Zfp933l1
Bone: cortical porosity 1837.29 1 1 4.2 0 1.00e+00 Retreg2
Bone: cortical porosity 4807.78 1 1 4.2 0 1.00e+00 Retreg2
Bone: cortical thickness 279.97 5 1 4.2 -1 2.22e-05 Cacul1 LOC120100068 Rab11fip2 Retreg2 Sfxn4
Bone: cortical thickness 12190.6 1 1 4.2 0 1.00e+00 Retreg2
Bone: cortical tissue density 9699.25 4 1 4.2 -0.89 4.12e-02 Grk5 LOC134485267 Retreg2 Sfxn4
Bone: elastic displacement 29626.25 1 1 4.2 0 1.00e+00 Retreg2
Bone: elastic work 1494.59 1 1 4.2 0 1.00e+00 Retreg2
Bone: endosteal estimation 35257.61 1 1 4.2 0 1.00e+00 Retreg2
Bone: endosteal perimeter 22353.48 2 1 4.2 0 1.00e+00 LOC134485258 Retreg2
Bone: final force 649.79 4 1 4.2 0.83 1.60e-03 Cacul1 Grk5 Retreg2 Sfxn4
Bone: final moment 106.26 4 1 4.2 0.93 3.48e-05 Cacul1 Grk5 Retreg2 Sfxn4
Bone: marrow area 37067.95 1 1 4.2 0 1.00e+00 Retreg2
Bone: maximum diameter 402.81 23 1 4.2 0.73 1.12e-11 Ablim1 Acsl5 Afap1l2 Cacul1 Casp7 Dclre1a Fhip2a Gfra1 Habp2 LOC102547573 LOC102556644 LOC120100061 LOC120100065 LOC134485255 LOC134485258 Nhlrc2 Nrap Plekhs1 Retreg2 Tcf7l2 Trub1 Vti1a Zdhhc6
Bone: maximum force 4944.16 3 1 4.2 0.83 1.94e-02 Cacul1 Grk5 Retreg2
Bone: maximum moment 3098.15 4 1 4.2 0.84 9.42e-03 Cacul1 Grk5 Retreg2 Sfxn4
Bone: minimum diameter 17196.64 1 1 4.2 0 1.00e+00 Retreg2
Bone: periosteal estimation 856.45 17 1 4.2 0.63 3.96e-06 Cacul1 Casp7 Ces2c Dennd10 Gpam Grk5 Habp2 LOC120100061 LOC134485255 LOC134485267 Nhlrc2 Prlhr Rab11fip2 Retreg2 Sfxn4 Tcf7l2 Vti1a
Bone: periosteal perimeter 282.67 37 2 8.3 0.58 1.55e-15 Ablim1 Acsl5 Afap1l2 Atrnl1 Cacul1 Casp7 Ccdc186 Ces2c Dclre1a Dennd10 Fhip2a Gfra1 Gpam Grk5 Gucy2g Habp2 LOC102547573 LOC102551125 LOC102556644 LOC120097692 LOC120100061 LOC120100065 LOC134485255 LOC134485257 LOC134485258 LOC134485267 Nhlrc2 Nrap Plekhs1 Rab11fip2 Retreg2 Sfxn4 Tcf7l2 Trub1 Vti1a Zdhhc6 Zfp933l1
Bone: post-yield work 50847.58 1 1 4.2 0 1.00e+00 Retreg2
Bone: stiffness 35564.91 1 1 4.2 0 1.00e+00 Retreg2
Bone: tissue strength 12264.67 1 1 4.2 0 1.00e+00 Retreg2
Bone: trabecular number 41138.39 1 1 4.2 0 1.00e+00 Retreg2
Bone: trabecular spacing 31287.85 1 1 4.2 0 1.00e+00 Retreg2
Bone: trabecular thickness 2229.65 6 1 4.2 0.79 4.34e-04 Cacul1 Grk5 LOC134485267 Rab11fip2 Retreg2 Sfxn4
Bone: trabecular tissue density 53620.06 1 1 4.2 0 1.00e+00 Retreg2
Breakpoint value in progressive ratio session 112428.06 1 1 4.2 0 1.00e+00 Retreg2
Distance traveled before self-admin 134013.73 1 1 4.2 0 1.00e+00 Retreg2
Distance traveled after self-admin 100820.36 1 1 4.2 0 1.00e+00 Retreg2
Delta time in closed arm before/after self-admin 1271.86 1 1 4.2 0 1.00e+00 Retreg2
Delta time in open arm before/after self-admin 54811.83 1 1 4.2 0 1.00e+00 Retreg2
Diff in mean of infusions in LGA sessions 108490.77 1 1 4.2 0 1.00e+00 Retreg2
Extinction: sum of active levers before priming 91573.47 1 1 4.2 0 1.00e+00 Retreg2
Active lever presses in extinction session 6 3117.3 1 1 4.2 0 1.00e+00 Retreg2
Delta distance traveled before/after self-admin 12434.77 1 1 4.2 0 1.00e+00 Retreg2
Delta ambulatory time before/after self-admin 96034.01 1 1 4.2 0 1.00e+00 Retreg2
Time in closed arm before self-admin 88239.28 1 1 4.2 0 1.00e+00 Retreg2
Time in closed arm after self-admin 19471.75 1 1 4.2 0 1.00e+00 Retreg2
Time in open arm before self-admin 34587.99 1 1 4.2 0 1.00e+00 Retreg2
Time in open arm after self-admin 1894.09 1 1 4.2 0 1.00e+00 Retreg2
Sum of active levers in priming session hrs 5-6 3877.89 1 1 4.2 0 1.00e+00 Retreg2
Time to tail flick, vehicle, before self-admin 51335.42 1 1 4.2 0 1.00e+00 Retreg2
Time to tail flick, vehicle, after self-admin 59148.38 2 1 4.2 0 1.00e+00 Gmppa Retreg2
Time to tail flick, test, before self-admin 32803.11 1 1 4.2 0 1.00e+00 Retreg2
Time to tail flick, test, after self-admin 5828.87 1 1 4.2 0 1.00e+00 Retreg2
Delta time to tail flick, vehicle, before/after SA 36533.83 1 1 4.2 0 1.00e+00 Retreg2
Delta time to tail flick, test, before/after SA 56832.34 1 1 4.2 0 1.00e+00 Retreg2
Ambulatory time before self-admin 171079.71 1 1 4.2 0 1.00e+00 Retreg2
Ambulatory time after self-admin 88230.17 1 1 4.2 0 1.00e+00 Retreg2
Total heroin consumption 961.5 1 1 4.2 0 1.00e+00 Retreg2
Area under the delay curve 81605.23 1 1 4.2 0 1.00e+00 Retreg2
Delay disc. indifference point, 0s delay 9477.47 1 1 4.2 0 1.00e+00 Retreg2
Delay disc. indifference point, 16s delay 74803.61 1 1 4.2 0 1.00e+00 Retreg2
Delay disc. indifference point, 2s delay 825.84 1 1 4.2 0 1.00e+00 Retreg2
Delay disc. indifference point, 24s delay 99983.64 1 1 4.2 0 1.00e+00 Retreg2
Delay disc. indifference point, 4s delay 2525.7 1 1 4.2 0 1.00e+00 Retreg2
Delay disc. indifference point, 8s delay 101423.99 1 1 4.2 0 1.00e+00 Retreg2
Delay discount exponential model param 60214.95 1 1 4.2 0 1.00e+00 Retreg2
Delay discount hyperbolic model param 45715.54 1 1 4.2 0 1.00e+00 Retreg2
Fecal boli incidents, locomotor time 1 150160.89 1 1 4.2 0 1.00e+00 Retreg2
Change in fecal boli incidents, locomotor task 23481.3 1 1 4.2 0 1.00e+00 Retreg2
Time >=10cm from walls, locomotor time 1 49255.61 1 1 4.2 0 1.00e+00 Retreg2
Bouts of movement, locomotor time 1 41590.88 1 1 4.2 0 1.00e+00 Retreg2
Total resting periods, locomotor time 1 11802.64 1 1 4.2 0 1.00e+00 Retreg2
Rest time, locomotor task time 1 75951.88 1 1 4.2 0 1.00e+00 Retreg2
Distance moved, locomotor task time 1 159283.67 1 1 4.2 0 1.00e+00 Retreg2
Vertical activity count, locomotor time 1 219061.96 1 1 4.2 0 1.00e+00 Retreg2
Time >=10cm from walls, locomotor time 2 161986.9 1 1 4.2 0 1.00e+00 Retreg2
Bouts of movement, locomotor time 2 174298.32 1 1 4.2 0 1.00e+00 Retreg2
Total resting periods, locomotor time 2 190079.87 1 1 4.2 0 1.00e+00 Retreg2
Rest time, locomotor task time 2 83778.18 1 1 4.2 0 1.00e+00 Retreg2
Distance moved, locomotor task time 2 34268.85 1 1 4.2 0 1.00e+00 Retreg2
Vertical activity count, locomotor time 2 138414.05 1 1 4.2 0 1.00e+00 Retreg2
Weight adjusted by age 161973.18 1 1 4.2 0 1.00e+00 Retreg2
Seeking ratio, delayed vs. immediate footshock 49395.56 1 1 4.2 0 1.00e+00 Retreg2
Locomotion in novel chamber 16301.47 1 1 4.2 0 1.00e+00 Retreg2
Locomotion in novel chamber post-restriction 154642.04 1 1 4.2 0 1.00e+00 Retreg2
Progressive ratio 157894.89 1 1 4.2 0 1.00e+00 Retreg2
Food seeking constrained by brief footshock 57.53 13 1 4.2 -0.8 7.41e-39 Asxl2 Dnmt3a Drc1 Dtnb Efr3b Garem2 Hadha Hadhb Kif3c Otof Rab10 Retreg2 Yipf4l1
Seeking ratio, punishment vs. effort 118281.2 1 1 4.2 0 1.00e+00 Retreg2
Run reversals in cocaine runway, females 37174.37 1 1 4.2 0 1.00e+00 Retreg2
Run reversals in cocaine runway, males 29861.56 1 1 4.2 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway 58575.8 1 1 4.2 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway, F 28379.24 1 1 4.2 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway, M 7140.1 1 1 4.2 0 1.00e+00 Retreg2
Co content in liver 4721.74 1 1 4.2 0 1.00e+00 Retreg2
Cu content in liver 162.43 1 1 4.2 0 1.00e+00 Retreg2
Fe content in liver 5656.2 1 1 4.2 0 1.00e+00 Retreg2
K content in liver 6593.53 1 1 4.2 0 1.00e+00 Retreg2
Mg content in liver 24493.99 1 1 4.2 0 1.00e+00 Retreg2
Mn content in liver 4374.36 1 1 4.2 0 1.00e+00 Retreg2
Na content in liver 16641.94 1 1 4.2 0 1.00e+00 Retreg2
Rb content in liver 428.45 1 1 4.2 0 1.00e+00 Retreg2
Zn content in liver 15755.62 1 1 4.2 0 1.00e+00 Retreg2

Associations by panel

Tissue RNA modality # hits % hits/tests Avg chisq
Adipose alternative polyA 9 0.2 2.21
Adipose alternative TSS 14 0.4 2.35
Adipose gene expression 46 0.5 2.37
Adipose isoform ratio 12 0.2 2.28
Adipose intron excision ratio 9 0.3 2.11
Adipose mRNA stability 19 0.4 2.36
BLA alternative polyA 14 0.6 2.22
BLA alternative TSS 4 0.2 2.29
BLA gene expression 28 0.4 2.36
BLA isoform ratio 11 0.4 2.23
BLA intron excision ratio 19 0.6 2.46
BLA mRNA stability 14 0.6 2.48
Brain alternative polyA 13 0.3 2.33
Brain alternative TSS 19 0.5 2.32
Brain gene expression 55 0.5 2.43
Brain isoform ratio 22 0.4 2.29
Brain intron excision ratio 25 0.4 2.42
Brain mRNA stability 23 0.4 2.38
Eye alternative polyA 1 0.4 2.43
Eye alternative TSS 0 0 2.08
Eye gene expression 3 0.2 2.27
Eye isoform ratio 4 0.7 2.26
Eye intron excision ratio 2 0.2 2.29
Eye mRNA stability 4 1.1 2.59
IC alternative polyA 11 0.6 2.42
IC alternative TSS 3 0.2 2.04
IC gene expression 35 0.5 2.46
IC isoform ratio 15 0.6 2.46
IC intron excision ratio 20 0.6 2.49
IC mRNA stability 13 0.8 2.52
IL alternative polyA 15 1.3 2.68
IL alternative TSS 1 0.1 2.18
IL gene expression 25 0.6 2.44
IL isoform ratio 6 0.5 2.35
IL intron excision ratio 7 0.6 2.69
IL mRNA stability 10 0.7 2.52
LHb alternative polyA 8 0.7 2.58
LHb alternative TSS 0 0 2.05
LHb gene expression 21 0.5 2.44
LHb isoform ratio 8 0.6 2.37
LHb intron excision ratio 8 0.7 2.35
LHb mRNA stability 11 0.9 2.55
Liver alternative polyA 14 0.5 2.34
Liver alternative TSS 11 0.4 2.35
Liver gene expression 29 0.4 2.31
Liver isoform ratio 24 0.7 2.4
Liver intron excision ratio 25 0.5 2.48
Liver mRNA stability 17 0.6 2.44
NAcc alternative polyA 17 0.5 2.7
NAcc alternative TSS 25 0.7 2.47
NAcc gene expression 51 0.5 2.43
NAcc isoform ratio 22 0.4 2.29
NAcc intron excision ratio 28 0.4 2.42
NAcc mRNA stability 16 0.4 2.37
OFC alternative polyA 11 0.9 2.52
OFC alternative TSS 3 0.4 2.26
OFC gene expression 24 0.5 2.47
OFC isoform ratio 6 0.4 2.3
OFC intron excision ratio 6 0.5 2.62
OFC mRNA stability 11 0.8 2.59
PL alternative polyA 14 0.4 2.36
PL alternative TSS 17 0.5 2.26
PL gene expression 47 0.5 2.41
PL isoform ratio 22 0.5 2.31
PL intron excision ratio 30 0.5 2.43
PL mRNA stability 21 0.5 2.41
pVTA alternative polyA 9 0.3 2.3
pVTA alternative TSS 10 0.4 2.34
pVTA gene expression 30 0.4 2.43
pVTA isoform ratio 12 0.3 2.23
pVTA intron excision ratio 14 0.3 2.41
pVTA mRNA stability 18 0.8 2.41
RMTg alternative polyA 2 0.3 2.14
RMTg alternative TSS 2 0.3 2.03
RMTg gene expression 13 0.6 2.64
RMTg isoform ratio 1 0.1 2.16
RMTg intron excision ratio 7 0.8 2.81
RMTg mRNA stability 4 0.6 2.54