Hub : Traits

Bone: trabecular tissue density

Tags: Physiology · Bone

Project: r01_doug_adams

5 loci · 5 genes with independent associations · 5 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr3	107934079	108540443	1	1	1.48e-07	3.00e-01	6.56e-37	Prr5l
2	chr7	92127461	93066096	1	1	6.61e-09	1.65e-01	1.00e+00	Ndufb9
3	chr8	117463629	118343328	1	1	1.50e-07	4.90e-01	1.00e+00	Mst1
4	chr9	83390749	84777604	1	1	0.00e+00	2.61e-01	1.00e+00	Retreg2
5	chr17	61510864	62906219	1	1	1.23e-08	1.55e-01	9.78e-01	Ccny

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	1285.12	3	2	40	0	1.00e+00	Ndufb9 Prr5l Retreg2
BMI without tail	36010.26	4	3	60	1	1.14e-03	Ccny Ndufb9 Prr5l Retreg2
Body weight	7.75	4	3	60	0.38	6.20e-01	Mst1 Ndufb9 Prr5l Retreg2
Epididymis fat weight	27130.87	4	3	60	1	2.12e-03	Ccny Mst1 Ndufb9 Retreg2
Glucose	825.95	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Heart weight	4511.78	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Left kidney weight	35317.59	4	2	40	-1	7.29e-04	Ccny Ndufb9 Prr5l Retreg2
Right kidney weight	29220.21	4	4	80	-1	1.11e-03	Ccny Mst1 Ndufb9 Retreg2
Tail length	30711.52	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Length with tail	2052.1	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Length without tail	32336.19	4	3	60	-1	1.13e-03	Ccny Mst1 Ndufb9 Retreg2
Liver weight, left	3639.22	4	3	60	-1	4.47e-03	Ccny Mst1 Ndufb9 Retreg2
Liver weight, right	60.98	5	2	40	-0.88	5.07e-02	Ccny Mst1 Ndufb9 Prr5l Retreg2
Parametrial fat weight	208.77	3	1	20	0	1.00e+00	Ccny Prr5l Retreg2
Retroperitoneal fat weight	8040.04	2	2	40	0	1.00e+00	Mst1 Retreg2
Intraocular pressure	40071.91	1	1	20	0	1.00e+00	Retreg2
Extensor digitorum longus weight	2342.82	2	1	20	0	1.00e+00	Mst1 Retreg2
Soleus weight	31.31	4	1	20	0.97	3.02e-02	Ccny Ndufb9 Prr5l Retreg2
Tibialis anterior weight	2447.14	2	2	40	0	1.00e+00	Prr5l Retreg2
Tibia length	825.24	4	3	60	0.99	5.02e-03	Mst1 Ndufb9 Prr5l Retreg2
Number of licking bursts	78561.42	2	1	20	0	1.00e+00	Ccny Retreg2
Food consumed during 24 hour testing period	35405.04	3	1	20	0	1.00e+00	Ccny Mst1 Retreg2
Times rat made contact with spout	158.46	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Mean time between licks in bursts	66503.89	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Mean num. licks in bursts	71302.54	2	1	20	0	1.00e+00	Ccny Retreg2
Std. dev. time between licks in bursts	47023.49	2	1	20	0	1.00e+00	Mst1 Retreg2
Water consumed over 24 hours	34476.6	3	1	20	0	1.00e+00	Ccny Prr5l Retreg2
Patch foraging indifference point 0 sec	38337.57	3	1	20	0	1.00e+00	Mst1 Prr5l Retreg2
Patch foraging indifference point AUC	26650.96	5	3	60	-1	1.02e-05	Ccny Mst1 Ndufb9 Prr5l Retreg2
Indifference point function ln k	35546.2	4	4	80	1	5.06e-04	Ccny Mst1 Ndufb9 Retreg2
Indifference point function log k	35546.2	4	4	80	1	5.06e-04	Ccny Mst1 Ndufb9 Retreg2
Patch foraging total patch changes 0 sec	40090.58	3	1	20	0	1.00e+00	Mst1 Prr5l Retreg2
Patch foraging total patch changes 12 sec	2223	5	4	80	0.99	1.33e-03	Ccny Mst1 Ndufb9 Prr5l Retreg2
Patch foraging total patch changes 18 sec	29448.67	4	1	20	1	5.59e-04	Ccny Mst1 Ndufb9 Retreg2
Patch foraging total patch changes 24 sec	41794.2	4	4	80	1	5.08e-04	Ccny Mst1 Ndufb9 Retreg2
Patch foraging total patch changes 6 sec	6547.3	5	3	60	1	2.09e-04	Ccny Mst1 Ndufb9 Prr5l Retreg2
Patch foraging time to switch 0 sec	39162.38	4	3	60	1	1.73e-05	Mst1 Ndufb9 Prr5l Retreg2
Patch foraging water rate 0 sec	49607.39	3	2	40	0	1.00e+00	Ndufb9 Prr5l Retreg2
Patch foraging water rate 12 sec	53969.51	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging water rate 18 sec	20660.83	5	1	20	-1	1.90e-05	Ccny Mst1 Ndufb9 Prr5l Retreg2
Patch foraging water rate 24 sec	1575.07	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging water rate 6 sec	1363.06	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Locomotor activity	29.73	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Locomotor testing distance	22395.71	4	3	60	-1	5.58e-05	Ccny Mst1 Ndufb9 Retreg2
Locomotor testing rearing	50810.53	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Light reinforcement 1	77669.42	2	2	40	0	1.00e+00	Ccny Retreg2
Light reinforcement 2	27019.19	4	3	60	-1	2.86e-03	Ccny Mst1 Ndufb9 Retreg2
Reaction time number correct	51168.28	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time mean minus median	51454.06	4	1	20	1	4.03e-04	Ccny Mst1 Ndufb9 Retreg2
Reaction time mean minus median AUC	69469.62	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Reaction time num false alarms	19041.41	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Reaction time num false alarms AUC	35512.53	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Reaction time trials correct on left	51168.28	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time trials on left	50013.45	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time mean	47192.43	2	1	20	0	1.00e+00	Ccny Retreg2
Reaction time mean AUC	56674.13	2	1	20	0	1.00e+00	Ccny Retreg2
Median of all reaction times	15711.8	2	1	20	0	1.00e+00	Prr5l Retreg2
Reaction time omissions	17137.2	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Reaction time false alarm rate	302.63	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Reaction time premature initiation rate	18442.81	2	1	20	0	1.00e+00	Ccny Retreg2
Reaction time premature initiations	69362.16	2	1	20	0	1.00e+00	Ccny Retreg2
Std. dev. reaction times	49831.92	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Reaction time trials completed	50013.45	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time trials AUC	50581.81	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Social response proportion	17657.99	2	1	20	0	1.00e+00	Mst1 Retreg2
Social responses	1150.43	5	2	40	-1	4.57e-06	Ccny Mst1 Ndufb9 Prr5l Retreg2
Social time	11065.2	4	1	20	1	4.88e-04	Ccny Mst1 Prr5l Retreg2
Conditioned locomotion	3044.63	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. corrected	32913.12	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. not corrected	32126.2	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response before conditioning	1409.02	2	1	20	0	1.00e+00	Ccny Retreg2
Saline control response	6522.43	2	2	40	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active minus inactive responses	26712.34	2	1	20	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active-inactive response ratio	45793.79	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active responses	4856.3	2	2	40	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. inactive responses	14046.99	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Condit. Reinf. lever presses	5308.92	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Condit. Reinf. lever reinforcers received	1007.39	2	1	20	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever latency	3648.25	3	1	20	0	1.00e+00	Mst1 Prr5l Retreg2
Pavlov. Cond. magazine entry latency	16518.76	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Pavlov. Cond. change in total contacts	57393.18	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. index score	16014.27	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Pavlov. Cond. latency score	14633.27	4	2	40	1	1.12e-03	Ccny Mst1 Prr5l Retreg2
Pavlov. Cond. lever contacts	7372.88	3	2	40	0	1.00e+00	Mst1 Prr5l Retreg2
Pavlov. Cond. magazine entry number	8453.95	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	35002.54	3	2	40	0	1.00e+00	Mst1 Prr5l Retreg2
Pavlov. Cond. lever-magazine prob. diff.	14975.97	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Pavlov. Cond. response bias	1755.38	3	2	40	0	1.00e+00	Mst1 Prr5l Retreg2
Conditioned reinforcement - actives	63842.12	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Conditioned reinforcement - inactives	38782.44	4	4	80	1	5.83e-04	Ccny Mst1 Ndufb9 Retreg2
Conditioned locomotion	8308.82	5	3	60	1	3.19e-05	Ccny Mst1 Ndufb9 Prr5l Retreg2
Intermittent access intake day 1-15 change	70205.74	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Intermittent access intake escalation	104773.43	2	1	20	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation 2	36035.56	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Intermitt. access day 1 inactive lever presses	59140.52	4	2	40	1	6.34e-04	Ccny Mst1 Ndufb9 Retreg2
Intermitt. access day 15 inactive lever presses	104145.18	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Intermitt. access escalation Index	46260.94	4	2	40	-1	5.35e-04	Ccny Mst1 Ndufb9 Retreg2
Intermittent access day 1 total infusions	51844.88	3	1	20	0	1.00e+00	Ccny Mst1 Retreg2
Intermittent access day 15 total infusions	65747.49	2	1	20	0	1.00e+00	Ccny Retreg2
Intermittent access terminal intake (last 3 days)	41604.86	2	1	20	0	1.00e+00	Ccny Retreg2
Intermittent access total infusions	345.81	2	1	20	0	1.00e+00	Ccny Retreg2
Intermittent access day 1 locomotion	52247.41	2	2	40	0	1.00e+00	Ccny Retreg2
Intermittent access day 15 total locomotion	88947.95	2	2	40	0	1.00e+00	Ccny Retreg2
Intermittent access total locomotion	243.62	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Intermittent access standard deviation	50491.84	4	3	60	1	1.68e-04	Ccny Mst1 Prr5l Retreg2
Cocaine induced anxiety	53447.41	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Post-drug Anxiety	6831.37	3	2	40	0	1.00e+00	Ndufb9 Prr5l Retreg2
Baseline Anxiety	34558.77	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Lifetime Intake	3437.35	2	2	40	0	1.00e+00	Ccny Retreg2
Incentive Sensitization - Responses	54538.05	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Incentive Sensitization - Breakpoint	47607.85	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio test 1 active lever presses	33313.84	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio test 1 breakpoint	32105.23	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio test 1 inactive lever presses	37785.58	4	4	80	1	4.98e-04	Ccny Mst1 Ndufb9 Retreg2
Progressive ratio test 2 active lever presses	19090.97	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio test 2 breakpoint	11681.84	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio test 2 inactive lever presses	41031.87	4	2	40	1	4.12e-04	Ccny Mst1 Ndufb9 Retreg2
Total sessions with >9 infusions	2022.77	4	3	60	-0.98	1.68e-02	Ccny Mst1 Prr5l Retreg2
Short access day 1 total inactive lever presses	22896.59	5	4	80	-1	2.44e-05	Ccny Mst1 Ndufb9 Prr5l Retreg2
Short access day 10 total inactive lever presses	54316.33	4	3	60	1	4.12e-05	Ccny Mst1 Prr5l Retreg2
Short access day 1 total infusions	37245.84	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Short access day 10 total infusions	15269.23	5	3	60	-1	6.54e-05	Ccny Mst1 Ndufb9 Prr5l Retreg2
Short access total infusions	17026.24	2	2	40	0	1.00e+00	Ccny Retreg2
Short access day 1 locomotion	21037.62	4	3	60	1	4.44e-04	Ccny Ndufb9 Prr5l Retreg2
Short access day 10 total locomotion	60537.65	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Short access total locomotion	17076.43	4	2	40	1	3.26e-04	Mst1 Ndufb9 Prr5l Retreg2
Compulsive drug intake	16366.41	4	1	20	-1	4.90e-04	Ccny Mst1 Ndufb9 Retreg2
One hour access (0.3 mA shock)	3241.22	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
One hour access (shock baseline)	70135.77	2	1	20	0	1.00e+00	Ccny Retreg2
Number of responses in last shaping day	17145.74	3	3	60	0	1.00e+00	Ccny Prr5l Retreg2
Context. condit. distance diff. score	488.1	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 1	7315.11	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Locomotion distance, session 1	2213.01	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 2	4702.2	2	2	40	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 2	806.64	3	1	20	0	1.00e+00	Ccny Mst1 Retreg2
Locomotion velocity, session 3	1177.39	2	1	20	0	1.00e+00	Prr5l Retreg2
Locomotion distance, session 3	16615.78	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	1968.48	3	1	20	0	1.00e+00	Mst1 Prr5l Retreg2
Stereotopy head waving duration, day 3	6074.03	2	1	20	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, session 7	708.6	2	2	40	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 7	1294.52	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Stereotopy head waving bouts, day 7	3507.59	3	2	40	0	1.00e+00	Ndufb9 Prr5l Retreg2
Stereotopy head waving duration, day 7	4446.48	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Locomotion velocity, session 8	635.82	3	1	20	0	1.00e+00	Ccny Prr5l Retreg2
Locomotion distance, session 8	673.32	1	1	20	0	1.00e+00	Retreg2
Degree of sensitization distance	7696.03	2	2	40	0	1.00e+00	Mst1 Retreg2
Degree of sensitization stereotypy	2841.03	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Condit. Reinf. active minus inactive responses	1389.25	3	2	40	0	1.00e+00	Ccny Prr5l Retreg2
Condit. Reinf. active-inactive response ratio	558.58	2	1	20	0	1.00e+00	Prr5l Retreg2
Condit. Reinf. active responses	3903.09	3	2	40	0	1.00e+00	Ccny Prr5l Retreg2
Condit. Reinf. inactive responses	6466.37	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Incentive salience index mean	3713.55	4	2	40	0.99	5.09e-03	Ccny Mst1 Prr5l Retreg2
Condit. Reinf. lever presses	7168.4	3	3	60	0	1.00e+00	Mst1 Prr5l Retreg2
Time in familiar zone, hab. session 1	13965.81	3	1	20	0	1.00e+00	Mst1 Prr5l Retreg2
Time in novel zone, hab. session 1	11855.76	3	2	40	0	1.00e+00	Mst1 Prr5l Retreg2
Total zone transitions, hab. session 1	916.07	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 1	849.35	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 1	571.33	2	1	20	0	1.00e+00	Ccny Retreg2
Time in familiar zone, hab. session 2	7808.35	3	2	40	0	1.00e+00	Mst1 Prr5l Retreg2
Time in novel zone, hab. session 2	8334.9	3	2	40	0	1.00e+00	Mst1 Prr5l Retreg2
Total zone transitions, hab. session 2	76.98	4	1	20	-1	2.97e-04	Mst1 Ndufb9 Prr5l Retreg2
Total locomotion distance, hab. session 2	39.55	3	1	20	0	1.00e+00	Ccny Prr5l Retreg2
Locomotion velocity, hab. session 2	56.5	3	1	20	0	1.00e+00	Ccny Prr5l Retreg2
Novel to familiar place preference ratio	13888.8	4	1	20	1	4.50e-04	Ccny Mst1 Prr5l Retreg2
Novelty place preference	13607.13	4	1	20	1	3.72e-04	Ccny Mst1 Prr5l Retreg2
Time in novel zone, NPP test	13626.92	3	1	20	0	1.00e+00	Mst1 Prr5l Retreg2
Total zone transitions, NPP test	4127.68	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, NPP test	3566.83	2	2	40	0	1.00e+00	Ccny Retreg2
Locomotion velocity, NPP test	2031.76	2	2	40	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever latency	563.82	4	2	40	0.98	1.77e-02	Mst1 Ndufb9 Prr5l Retreg2
Pavlov. Cond. magazine entry latency	8.96	2	0	0	0	1.00e+00	Ccny Prr5l
Pavlov. Cond. change in total contacts	1523.84	3	1	20	0	1.00e+00	Ccny Prr5l Retreg2
Pavlov. Cond. index score	603.88	3	2	40	0	1.00e+00	Mst1 Prr5l Retreg2
Pavlov. Cond. latency score	628.33	3	2	40	0	1.00e+00	Mst1 Prr5l Retreg2
Pavlov. Cond. lever contacts	775.63	4	2	40	-0.98	1.55e-02	Mst1 Ndufb9 Prr5l Retreg2
Pavlov. Cond. magazine entry number	550.77	4	2	40	0.99	9.95e-03	Ccny Mst1 Prr5l Retreg2
Pavlov. Cond. intertrial magazine entries	152.73	4	3	60	0.92	7.85e-02	Mst1 Ndufb9 Prr5l Retreg2
Pavlov. Cond. lever-magazine prob. diff.	656.26	3	1	20	0	1.00e+00	Mst1 Prr5l Retreg2
Pavlov. Cond. response bias	880.36	3	1	20	0	1.00e+00	Mst1 Prr5l Retreg2
Bone: apparent density	7427.93	3	1	20	0	1.00e+00	Ndufb9 Prr5l Retreg2
Bone surface	8383.75	3	2	40	0	1.00e+00	Mst1 Prr5l Retreg2
Bone volume	16919.6	2	1	20	0	1.00e+00	Mst1 Retreg2
Bone: connectivity density	1788.3	4	2	40	1	6.65e-04	Mst1 Ndufb9 Prr5l Retreg2
Bone: cortical apparent density	15092.86	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Bone: cortical area	6332.51	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: cortical porosity	471.17	4	2	40	-0.99	1.48e-02	Mst1 Ndufb9 Prr5l Retreg2
Bone: cortical porosity	1212.51	4	2	40	1	4.60e-03	Mst1 Ndufb9 Prr5l Retreg2
Bone: cortical thickness	566.34	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: cortical thickness	3064.07	4	2	40	-1	3.50e-03	Mst1 Ndufb9 Prr5l Retreg2
Bone: cortical tissue density	16155.62	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Bone: elastic displacement	29626.25	1	1	20	0	1.00e+00	Retreg2
Bone: elastic work	507.3	3	2	40	0	1.00e+00	Mst1 Prr5l Retreg2
Bone: endosteal estimation	11756.25	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: endosteal perimeter	14902.29	3	1	20	0	1.00e+00	Mst1 Prr5l Retreg2
Bone: final force	3544.85	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: final moment	548.75	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: marrow area	12360.31	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: maximum diameter	8150.69	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: maximum force	17305.93	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: maximum moment	8258.6	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: minimum diameter	8606.13	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: periosteal estimation	19111.51	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: periosteal perimeter	21606.9	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: post-yield work	25428.45	2	1	20	0	1.00e+00	Mst1 Retreg2
Bone: stiffness	17808.98	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: tissue strength	6136.63	2	1	20	0	1.00e+00	Prr5l Retreg2
Bone: trabecular number	13724.52	3	2	40	0	1.00e+00	Ndufb9 Prr5l Retreg2
Bone: trabecular spacing	10445.17	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: trabecular thickness	11101.04	3	2	40	0	1.00e+00	Mst1 Prr5l Retreg2
Breakpoint value in progressive ratio session	37483.32	3	1	20	0	1.00e+00	Ccny Mst1 Retreg2
Distance traveled before self-admin	44694.41	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Distance traveled after self-admin	50469.31	2	2	40	0	1.00e+00	Ccny Retreg2
Delta time in closed arm before/after self-admin	689.79	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Delta time in open arm before/after self-admin	18296.52	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Diff in mean of infusions in LGA sessions	36170.06	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Extinction: sum of active levers before priming	22955.29	4	4	80	1	1.61e-03	Ccny Mst1 Ndufb9 Retreg2
Active lever presses in extinction session 6	1124.21	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Delta distance traveled before/after self-admin	4205.11	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Delta ambulatory time before/after self-admin	32036.91	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Time in closed arm before self-admin	29438.21	3	3	60	0	1.00e+00	Ccny Mst1 Retreg2
Time in closed arm after self-admin	6616.57	3	3	60	0	1.00e+00	Ccny Mst1 Retreg2
Time in open arm before self-admin	8700.62	4	3	60	-1	1.88e-03	Ccny Mst1 Ndufb9 Retreg2
Time in open arm after self-admin	518.44	4	4	80	0.95	5.29e-02	Ccny Mst1 Ndufb9 Retreg2
Sum of active levers in priming session hrs 5-6	1945.79	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Time to tail flick, vehicle, before self-admin	12972.56	4	2	40	0.99	6.17e-03	Ccny Mst1 Ndufb9 Retreg2
Time to tail flick, vehicle, after self-admin	39443.57	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Time to tail flick, test, before self-admin	6575.38	5	2	40	-1	2.33e-05	Ccny Mst1 Ndufb9 Prr5l Retreg2
Time to tail flick, test, after self-admin	1519.96	4	3	60	0.96	3.59e-02	Ccny Ndufb9 Prr5l Retreg2
Delta time to tail flick, vehicle, before/after SA	12309.52	3	3	60	0	1.00e+00	Ccny Mst1 Retreg2
Delta time to tail flick, test, before/after SA	14216.41	4	1	20	1	1.91e-03	Ccny Mst1 Ndufb9 Retreg2
Ambulatory time before self-admin	85572.63	2	2	40	0	1.00e+00	Ccny Retreg2
Ambulatory time after self-admin	29437.11	3	2	40	0	1.00e+00	Ccny Mst1 Retreg2
Total heroin consumption	547.18	2	2	40	0	1.00e+00	Ccny Retreg2
Area under the delay curve	40810.48	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 0s delay	4741.82	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 16s delay	37437.33	2	2	40	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 2s delay	416.46	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 24s delay	50025	2	2	40	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 4s delay	870.6	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Delay disc. indifference point, 8s delay	101423.99	1	1	20	0	1.00e+00	Retreg2
Delay discount exponential model param	30110.07	2	1	20	0	1.00e+00	Ccny Retreg2
Delay discount hyperbolic model param	45715.54	1	1	20	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	75084.64	2	1	20	0	1.00e+00	Ccny Retreg2
Change in fecal boli incidents, locomotor task	5921.12	4	3	60	1	3.39e-03	Ccny Ndufb9 Prr5l Retreg2
Time >=10cm from walls, locomotor time 1	16438.93	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Bouts of movement, locomotor time 1	13896.68	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Total resting periods, locomotor time 1	5936.78	2	2	40	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 1	18997.04	4	1	20	1	1.73e-03	Ccny Ndufb9 Prr5l Retreg2
Distance moved, locomotor task time 1	53112.82	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Vertical activity count, locomotor time 1	219061.96	1	1	20	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	80995.71	2	1	20	0	1.00e+00	Ccny Retreg2
Bouts of movement, locomotor time 2	87164.71	2	2	40	0	1.00e+00	Ccny Retreg2
Total resting periods, locomotor time 2	95051.56	2	2	40	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 2	27936.17	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Distance moved, locomotor task time 2	17217.33	2	2	40	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 2	69238.05	2	2	40	0	1.00e+00	Ccny Retreg2
Weight adjusted by age	54026.61	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Seeking ratio, delayed vs. immediate footshock	24709.08	2	2	40	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber	4104.78	4	3	60	-1	4.48e-03	Ccny Ndufb9 Prr5l Retreg2
Locomotion in novel chamber post-restriction	51551.01	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio	39494.45	4	3	60	-1	1.83e-03	Ccny Ndufb9 Prr5l Retreg2
Food seeking constrained by brief footshock	3673.46	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, punishment vs. effort	29579.01	4	3	60	1	1.44e-03	Ccny Ndufb9 Prr5l Retreg2
Run reversals in cocaine runway, females	18598.36	2	1	20	0	1.00e+00	Ccny Retreg2
Run reversals in cocaine runway, males	9993.2	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Latency to leave start box in cocaine runway	29317.55	2	2	40	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway, F	14201.52	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Latency to leave start box in cocaine runway, M	2456.15	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Cd content in liver	11.42	1	0	0	0	1.00e+00	Prr5l
Co content in liver	2368.81	2	1	20	0	1.00e+00	Prr5l Retreg2
Cu content in liver	89.33	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Fe content in liver	5656.2	1	1	20	0	1.00e+00	Retreg2
K content in liver	6593.53	1	1	20	0	1.00e+00	Retreg2
Mg content in liver	12253.35	2	1	20	0	1.00e+00	Prr5l Retreg2
Mn content in liver	2219.37	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Na content in liver	8325.4	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Rb content in liver	163.29	3	2	40	0	1.00e+00	Ndufb9 Prr5l Retreg2
Se content in liver	11.09	2	0	0	0	1.00e+00	Ndufb9 Prr5l
Zn content in liver	7891.81	2	2	40	0	1.00e+00	Ndufb9 Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.41
Adipose	alternative TSS	0	0	1.45
Adipose	gene expression	0	0	1.39
Adipose	isoform ratio	0	0	1.37
Adipose	intron excision ratio	0	0	1.21
Adipose	mRNA stability	1	0	1.41
BLA	alternative polyA	0	0	1.56
BLA	alternative TSS	0	0	1.38
BLA	gene expression	0	0	1.43
BLA	isoform ratio	0	0	1.42
BLA	intron excision ratio	0	0	1.37
BLA	mRNA stability	0	0	1.4
Brain	alternative polyA	0	0	1.48
Brain	alternative TSS	0	0	1.34
Brain	gene expression	0	0	1.39
Brain	isoform ratio	0	0	1.4
Brain	intron excision ratio	0	0	1.36
Brain	mRNA stability	0	0	1.42
Eye	alternative polyA	0	0	1.4
Eye	alternative TSS	0	0	1.34
Eye	gene expression	0	0	1.52
Eye	isoform ratio	0	0	1.45
Eye	intron excision ratio	0	0	1.43
Eye	mRNA stability	0	0	1.4
IC	alternative polyA	0	0	1.47
IC	alternative TSS	0	0	1.43
IC	gene expression	0	0	1.42
IC	isoform ratio	0	0	1.43
IC	intron excision ratio	0	0	1.38
IC	mRNA stability	0	0	1.4
IL	alternative polyA	0	0	1.42
IL	alternative TSS	0	0	1.27
IL	gene expression	0	0	1.41
IL	isoform ratio	0	0	1.5
IL	intron excision ratio	0	0	1.3
IL	mRNA stability	0	0	1.35
LHb	alternative polyA	0	0	1.53
LHb	alternative TSS	0	0	1.51
LHb	gene expression	0	0	1.45
LHb	isoform ratio	0	0	1.47
LHb	intron excision ratio	0	0	1.36
LHb	mRNA stability	0	0	1.47
Liver	alternative polyA	0	0	1.38
Liver	alternative TSS	0	0	1.38
Liver	gene expression	0	0	1.37
Liver	isoform ratio	1	0	1.39
Liver	intron excision ratio	0	0	1.35
Liver	mRNA stability	0	0	1.39
NAcc	alternative polyA	1	0	27.83
NAcc	alternative TSS	0	0	1.35
NAcc	gene expression	0	0	1.43
NAcc	isoform ratio	0	0	1.44
NAcc	intron excision ratio	0	0	1.35
NAcc	mRNA stability	0	0	1.43
OFC	alternative polyA	0	0	1.59
OFC	alternative TSS	0	0	1.28
OFC	gene expression	0	0	1.44
OFC	isoform ratio	0	0	1.38
OFC	intron excision ratio	0	0	1.47
OFC	mRNA stability	0	0	1.41
PL	alternative polyA	0	0	1.49
PL	alternative TSS	0	0	1.37
PL	gene expression	0	0	1.4
PL	isoform ratio	0	0	1.47
PL	intron excision ratio	0	0	1.38
PL	mRNA stability	0	0	1.41
pVTA	alternative polyA	0	0	1.53
pVTA	alternative TSS	0	0	1.39
pVTA	gene expression	1	0	1.45
pVTA	isoform ratio	0	0	1.42
pVTA	intron excision ratio	0	0	1.4
pVTA	mRNA stability	1	0	1.45
RMTg	alternative polyA	0	0	1.51
RMTg	alternative TSS	0	0	1.18
RMTg	gene expression	0	0	1.36
RMTg	isoform ratio	0	0	1.45
RMTg	intron excision ratio	0	0	1.45
RMTg	mRNA stability	0	0	1.3