Hub : Genes

Arhgef18

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Arhgef18 0.11 0.06 2.6e-06 0.06 0.06 0.06 0.07 1.4e-06 1.1e-06 1.3e-06 9.8e-07
2 IC intron excision ratio chr12_6233723_6272690 0.11 0.07 5.4e-03 0.04 0.04 0.02 0.03 1.0e-02 6.6e-03 5.4e-02 1.8e-02
3 PL isoform ratio XM_063271245.1 0.08 0.05 1.0e-04 0.04 0.04 0.04 0.04 1.1e-05 8.3e-05 2.6e-05 7.3e-05
4 PL alternative TSS XM_063271245.1 0.07 0.05 2.9e-04 0.04 0.03 0.04 0.03 3.9e-05 2.3e-04 3.9e-05 2.2e-04
5 pVTA gene expression Arhgef18 0.29 0.11 0.0e+00 0.21 0.25 0.22 0.25 8.3e-17 7.6e-20 1.6e-17 3.9e-20
6 IC intron excision ratio chr12_6238847_6272690 0.15 0.09 9.4e-04 0.07 0.09 0.08 0.08 4.7e-04 1.1e-04 3.3e-04 2.3e-04
7 pVTA mRNA stability Arhgef18 0.04 0.03 3.0e-03 0.01 0.01 0 0 8.8e-02 3.5e-02 1.8e-01 1.1e-01
8 NAcc gene expression Arhgef18 0.08 0.04 2.7e-09 0.06 0.06 0.06 0.06 2.3e-09 1.2e-09 1.4e-09 2.0e-09
9 BLA alternative TSS XM_063271245.1 0.22 0.1 3.1e-08 0.11 0.16 0.14 0.14 1.9e-06 7.8e-09 4.6e-08 4.8e-08
10 pVTA isoform ratio XM_063271245.1 0.09 0.05 1.2e-04 0.03 0.06 0.05 0.05 1.7e-03 2.0e-05 4.9e-05 6.0e-05
11 pVTA alternative TSS XM_063271245.1 0.06 0.04 3.0e-03 0.02 0.03 0.03 0.03 1.9e-02 8.7e-04 1.8e-03 1.6e-03
12 PL gene expression Arhgef18 0.04 0.02 2.6e-03 0.02 0.02 0.01 0.02 3.6e-03 1.7e-03 2.2e-02 3.1e-03
13 BLA isoform ratio XM_063271245.1 0.19 0.09 1.2e-07 0.12 0.13 0.11 0.12 7.4e-07 2.2e-07 1.8e-06 6.2e-07
14 Eye alternative TSS XM_063271245.1 0.31 0.16 5.0e-03 0.12 0.18 0.13 0.16 7.7e-03 9.4e-04 5.8e-03 1.7e-03
15 BLA gene expression Arhgef18 0.11 0.06 8.2e-05 0.08 0.08 0.06 0.08 6.0e-05 7.3e-05 3.6e-04 7.8e-05
16 Adipose gene expression Arhgef18 0.35 0.15 0.0e+00 0.24 0.25 0.25 0.24 1.5e-26 4.1e-27 3.6e-27 1.0e-26
17 NAcc mRNA stability Arhgef18 0.04 0.03 2.5e-05 0.03 0.03 0.02 0.02 8.4e-05 5.1e-05 4.9e-04 4.8e-04
18 Liver mRNA stability Arhgef18 0.03 0.02 2.3e-03 0.02 0.02 0.02 0.02 1.3e-03 2.4e-03 3.2e-03 1.9e-03
19 PL mRNA stability Arhgef18 0.03 0.02 4.6e-04 0.03 0.03 0.03 0.03 1.7e-04 4.7e-04 5.5e-04 1.9e-04
20 PL intron excision ratio chr12_6238847_6272690 0.04 0.03 1.1e-04 0.02 0.03 0.03 0.02 3.2e-03 2.3e-04 1.3e-04 1.1e-03
21 LHb mRNA stability Arhgef18 0.17 0.1 2.9e-03 0.06 0.11 0.11 0.1 1.3e-02 1.2e-03 1.4e-03 1.9e-03
22 Adipose mRNA stability Arhgef18 0.04 0.02 2.8e-04 0.03 0.03 0.02 0.03 1.4e-04 6.3e-04 1.9e-03 3.7e-04
23 Brain mRNA stability Arhgef18 0.03 0.02 2.9e-03 0.01 0.01 0.01 0.01 2.0e-02 1.2e-02 8.0e-02 6.0e-02
24 PL intron excision ratio chr12_6233723_6272690 0.04 0.02 4.9e-04 0.01 0.02 0.03 0.01 1.9e-02 1.1e-03 4.3e-04 8.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density1.93.210.1-2.8-2.32.62.6-2.01.83.2-1.61.31.41.4-1.11.00.9-0.7-2.32.12.02.0-0.40.3-1.50.70.9
Area under the delay curve1.51.85.60.90.6-1.0-1.00.1-0.2-2.2-0.30.3-0.1-0.1-0.60.60.7-0.92.4-2.1-2.3-2.21.0-1.62.1-1.7-1.1
BMI with tail0.82.88.5-2.9-2.22.22.2-2.61.82.4-2.41.91.01.0-1.91.81.7-1.2-1.21.50.60.80.2-0.9-0.6-0.50.6
BMI without tail2.67.916.5-3.9-3.73.43.4-4.13.42.2-3.93.62.82.7-3.53.53.4-3.0-0.40.5-0.4-0.31.9-2.30.4-1.9-1.2
Body weight8.135.577.2-8.7-8.27.57.5-8.87.45.8-8.17.66.05.9-7.27.16.8-5.8-1.92.10.20.53.7-4.2-0.0-3.2-2.0
Weight adjusted by age0.50.72.6-1.3-0.90.80.8-0.90.61.6-0.60.50.40.4-0.30.30.20.1-1.41.31.11.0-0.40.4-1.40.50.4
Bone surface2.13.910.0-3.2-2.82.72.7-2.82.42.8-2.52.21.81.8-2.01.91.8-1.5-1.51.61.01.10.4-0.7-0.5-0.30.3
Bone volume1.11.96.6-2.3-1.71.91.9-1.81.32.6-1.51.10.80.8-1.00.90.8-0.5-1.71.81.41.4-0.50.0-1.00.41.0
Breakpoint value in progressive ratio session0.81.02.2-0.1-0.40.40.4-0.60.6-0.9-0.90.80.60.6-1.00.91.0-1.21.3-1.2-1.3-1.31.1-1.31.5-1.4-1.1
Number of licking bursts0.40.71.9-1.1-1.01.11.1-0.60.71.4-0.20.60.70.7-0.00.30.10.0-1.21.21.21.20.30.8-0.90.8-0.4
Context. condit. distance diff. score3.44.16.5-2.1-2.42.12.1-2.52.50.5-2.52.42.32.3-2.52.42.4-2.40.6-0.9-1.0-1.11.9-2.11.1-1.9-1.6
Locomotion velocity, session 10.50.52.10.90.6-0.8-0.80.5-0.4-1.20.3-0.2-0.2-0.20.1-0.1-0.00.01.2-1.0-0.9-0.90.6-0.51.4-0.6-0.7
Locomotion distance, session 10.70.92.61.61.3-1.2-1.21.3-1.0-1.41.1-1.0-0.7-0.60.9-0.9-0.80.60.9-1.0-0.6-0.6-0.10.20.90.0-0.2
Locomotion velocity, session 20.30.31.00.60.2-0.4-0.40.3-0.1-1.00.10.00.10.1-0.10.10.2-0.31.0-0.9-0.8-0.80.7-0.41.0-0.5-0.8
Locomotion distance, session 20.50.82.41.51.0-0.8-0.81.5-0.7-1.61.3-0.9-0.1-0.00.9-0.8-0.80.40.9-1.3-0.4-0.40.10.40.70.1-0.5
Locomotion velocity, session 30.30.30.5-0.4-0.50.40.4-0.60.6-0.1-0.70.60.60.6-0.70.60.7-0.70.4-0.5-0.5-0.50.5-0.70.5-0.7-0.4
Locomotion distance, session 30.20.20.60.20.20.10.10.5-0.20.30.6-0.5-0.1-0.00.6-0.6-0.60.4-0.60.40.70.7-0.50.7-0.80.70.4
Stereotopy head waving bouts, day 31.51.84.7-2.2-1.81.91.9-1.71.62.0-1.31.31.31.3-1.11.11.0-0.8-1.41.21.01.00.3-0.1-1.40.10.1
Stereotopy head waving duration, day 30.10.10.5-0.20.1-0.1-0.10.0-0.20.50.1-0.2-0.3-0.30.3-0.3-0.30.4-0.60.60.50.5-0.50.4-0.70.50.6
Locomotion velocity, session 71.31.54.10.90.5-1.0-1.00.0-0.2-1.9-0.30.3-0.1-0.2-0.50.50.7-0.62.0-1.7-1.9-2.01.3-1.42.0-1.5-1.4
Locomotion distance, session 70.81.03.10.60.1-0.2-0.20.00.3-1.6-0.20.40.60.6-0.60.60.7-0.91.5-1.8-1.5-1.51.2-1.11.3-1.3-1.4
Stereotopy head waving bouts, day 70.10.10.50.60.4-0.4-0.40.4-0.2-0.70.3-0.3-0.00.00.2-0.2-0.10.00.5-0.6-0.4-0.40.2-0.10.3-0.2-0.3
Stereotopy head waving duration, day 70.30.41.11.10.8-0.9-0.90.8-0.7-0.90.7-0.7-0.6-0.60.5-0.6-0.50.50.5-0.5-0.4-0.4-0.20.10.4-0.00.1
Locomotion velocity, session 80.50.61.0-0.2-0.40.20.2-0.70.5-0.5-0.80.80.50.4-0.80.80.9-0.80.8-0.7-0.9-1.01.0-1.00.9-1.0-1.0
Locomotion distance, session 81.21.72.7-1.1-1.41.21.2-1.51.50.0-1.61.61.51.5-1.61.61.6-1.60.7-0.8-0.9-0.91.3-1.41.3-1.4-1.1
Degree of sensitization distance0.80.93.21.10.7-0.9-0.90.5-0.4-1.80.2-0.1-0.1-0.1-0.00.10.2-0.31.6-1.5-1.4-1.40.8-0.81.3-0.9-1.0
Degree of sensitization stereotypy0.30.30.90.90.7-0.8-0.80.6-0.5-0.90.4-0.4-0.4-0.40.3-0.3-0.20.20.7-0.7-0.6-0.60.1-0.20.6-0.3-0.2
Conditioned locomotion0.40.52.1-0.10.2-0.0-0.00.4-0.40.80.5-0.6-0.4-0.40.6-0.6-0.70.6-1.10.90.90.9-0.90.8-1.40.91.0
Cocaine response after cond. corrected0.60.82.4-0.20.5-0.6-0.6-0.1-0.91.00.0-0.4-1.5-1.50.4-0.5-0.51.1-0.91.60.80.8-1.00.5-0.70.71.4
Cocaine response after cond. not corrected0.20.21.2-0.10.3-0.6-0.6-0.3-0.60.4-0.3-0.1-1.1-1.1-0.0-0.1-0.00.6-0.20.80.10.1-0.5-0.1-0.00.00.8
Cocaine response before conditioning1.21.43.4-0.0-0.50.40.4-0.60.9-1.2-0.80.81.21.3-1.11.01.1-1.41.4-1.9-1.4-1.41.4-1.51.4-1.5-1.5
Saline control response2.63.48.5-2.4-2.62.92.9-1.82.61.3-1.52.02.82.8-1.61.81.5-2.0-0.70.00.40.41.6-0.5-0.6-0.5-1.6
Bone: connectivity density3.35.112.4-3.5-3.23.43.4-3.02.93.1-2.62.42.42.4-2.22.11.9-1.8-1.81.51.31.30.7-0.6-0.7-0.2-0.1
Bone: cortical apparent density0.30.41.00.70.6-0.9-0.90.3-0.5-1.00.1-0.2-0.6-0.60.0-0.00.10.10.9-0.6-0.9-1.00.2-0.50.6-0.6-0.3
Bone: cortical area2.33.56.1-1.8-2.01.51.5-2.42.10.1-2.52.31.81.8-2.42.42.4-2.20.9-0.9-1.3-1.31.9-2.21.3-2.0-1.5
Bone: cortical porosity0.10.10.3-0.3-0.20.40.4-0.00.20.50.1-0.00.20.20.1-0.1-0.20.1-0.50.40.50.5-0.10.4-0.50.40.1
Bone: cortical porosity0.00.00.10.30.2-0.0-0.00.4-0.1-0.30.4-0.30.10.10.2-0.2-0.20.10.1-0.3-0.0-0.00.00.20.10.1-0.2
Bone: cortical thickness1.72.85.0-1.8-1.91.61.6-2.21.90.4-2.22.11.71.6-2.22.12.1-1.90.5-0.5-1.0-1.01.6-1.80.7-1.6-1.3
Bone: cortical thickness1.61.93.0-1.4-1.61.51.5-1.61.70.2-1.51.61.71.7-1.61.61.6-1.70.4-0.7-0.7-0.61.4-1.20.6-1.2-1.3
Bone: cortical tissue density0.30.30.90.80.7-0.9-0.90.4-0.6-0.90.2-0.3-0.7-0.70.2-0.2-0.10.20.8-0.5-0.8-0.80.1-0.40.5-0.4-0.2
Condit. Reinf. active minus inactive responses0.50.51.41.10.9-1.2-1.20.6-0.8-1.10.4-0.6-0.8-0.80.3-0.4-0.30.40.8-0.7-0.8-0.80.0-0.30.5-0.4-0.2
Condit. Reinf. active-inactive response ratio0.30.30.90.60.5-0.8-0.80.1-0.5-0.9-0.1-0.1-0.6-0.6-0.20.10.20.00.8-0.7-1.0-1.00.3-0.70.6-0.7-0.3
Condit. Reinf. active responses0.30.41.51.00.7-0.8-0.80.6-0.4-1.20.4-0.4-0.2-0.20.2-0.2-0.10.00.9-1.1-0.8-0.80.3-0.40.7-0.5-0.5
Condit. Reinf. inactive responses0.40.41.81.10.6-0.5-0.50.9-0.2-1.30.8-0.50.20.30.4-0.4-0.3-0.10.9-1.3-0.6-0.70.2-0.00.6-0.3-0.6
Incentive salience index mean0.40.41.41.10.9-0.9-0.90.7-0.7-1.20.5-0.6-0.5-0.50.4-0.4-0.30.30.8-0.9-0.7-0.70.0-0.20.4-0.3-0.2
Condit. Reinf. lever presses0.20.31.00.80.7-0.5-0.50.7-0.4-1.00.5-0.6-0.1-0.10.3-0.4-0.30.10.6-1.0-0.5-0.5-0.0-0.10.4-0.2-0.2
Condit. Reinf. active minus inactive responses2.73.66.4-1.1-1.61.31.3-1.71.9-0.7-1.92.12.02.0-2.12.22.2-2.21.5-1.6-1.6-1.62.5-2.12.1-2.1-2.5
Condit. Reinf. active-inactive response ratio1.92.35.2-0.4-0.90.60.6-1.01.2-1.1-1.21.51.41.4-1.51.61.6-1.61.7-1.7-1.6-1.62.1-1.72.2-1.8-2.3
Condit. Reinf. active responses3.04.27.0-1.3-1.81.51.5-1.92.1-0.8-2.12.22.22.2-2.32.32.4-2.51.6-1.8-1.8-1.82.6-2.32.0-2.3-2.6
Condit. Reinf. inactive responses0.50.61.1-0.8-0.91.01.0-0.91.00.1-0.90.91.11.1-1.00.90.9-1.00.2-0.5-0.4-0.40.8-0.80.1-0.8-0.7
Condit. Reinf. lever presses0.50.71.3-0.2-0.50.30.3-0.60.7-0.6-0.70.70.80.8-0.90.80.9-0.90.9-1.1-0.8-0.81.1-1.01.1-1.1-1.1
Condit. Reinf. lever reinforcers received2.63.66.6-0.9-1.51.21.2-1.51.8-1.1-1.81.92.02.0-2.12.12.1-2.31.7-2.0-1.9-1.82.5-2.22.1-2.3-2.6
Conditioned reinforcement - actives1.93.26.5-2.1-2.52.22.2-2.42.51.3-2.22.32.32.3-2.12.12.0-1.8-0.50.1-0.00.01.6-1.2-0.0-1.0-1.3
Conditioned reinforcement - inactives0.30.51.2-0.6-0.70.90.9-0.30.61.1-0.00.30.60.60.00.1-0.1-0.0-1.10.81.01.0-0.20.6-1.00.70.0
Conditioned locomotion2.22.85.3-1.7-2.12.12.1-1.92.30.6-1.91.92.32.3-1.91.91.8-2.00.1-0.6-0.4-0.41.7-1.40.4-1.3-1.6
Patch foraging indifference point 0 sec1.12.14.8-0.20.20.30.30.8-0.51.81.1-1.1-0.6-0.61.3-1.3-1.41.3-2.11.92.22.2-1.82.0-2.02.01.8
Patch foraging indifference point AUC0.71.02.3-1.5-1.41.51.5-1.21.31.4-1.01.11.11.1-0.90.90.8-0.7-0.90.70.60.60.4-0.1-0.80.0-0.2
Delay disc. indifference point, 0s delay1.82.04.5-0.5-0.5-0.2-0.2-1.40.5-0.9-1.71.40.0-0.0-1.61.61.7-1.31.8-1.0-2.0-2.11.6-2.12.0-2.0-1.3
Delay disc. indifference point, 16s delay0.50.61.60.60.3-0.8-0.80.1-0.1-1.3-0.10.10.00.0-0.30.30.4-0.31.3-1.2-1.3-1.20.7-0.81.1-0.9-0.8
Delay disc. indifference point, 2s delay2.42.77.91.61.3-1.8-1.80.6-0.9-2.8-0.1-0.2-0.9-0.9-0.30.20.5-0.52.8-2.4-2.7-2.70.7-1.72.4-1.9-0.7
Delay disc. indifference point, 24s delay0.50.61.91.10.8-1.1-1.10.6-0.6-1.40.5-0.4-0.4-0.40.3-0.2-0.10.01.1-1.0-1.0-0.80.4-0.30.8-0.5-0.6
Delay disc. indifference point, 4s delay1.21.33.90.90.8-1.1-1.10.2-0.5-1.9-0.2-0.0-0.4-0.5-0.40.30.5-0.62.0-1.7-1.9-1.90.5-1.31.8-1.4-0.5
Delay disc. indifference point, 8s delay0.60.72.50.40.2-0.1-0.10.20.1-1.5-0.10.20.40.4-0.40.40.5-0.91.5-1.6-1.4-1.30.5-0.91.3-1.1-0.7
Indifference point function ln k0.00.10.20.1-0.10.30.30.30.2-0.20.3-0.10.50.50.2-0.1-0.2-0.1-0.0-0.30.20.30.20.30.20.2-0.4
Indifference point function log k0.00.10.20.1-0.10.30.30.30.2-0.20.3-0.10.50.50.2-0.1-0.2-0.1-0.0-0.30.20.30.20.30.20.2-0.4
Patch foraging total patch changes 0 sec1.42.76.4-0.10.30.30.30.9-0.61.91.3-1.2-0.6-0.61.5-1.5-1.71.5-2.42.12.52.5-2.02.3-2.32.31.9
Patch foraging total patch changes 12 sec0.91.23.6-0.8-0.40.60.6-0.20.01.90.0-0.2-0.2-0.20.4-0.4-0.50.8-1.81.81.61.6-1.21.1-1.91.31.4
Patch foraging total patch changes 18 sec1.52.25.5-0.5-0.10.60.60.5-0.32.10.8-0.8-0.4-0.41.1-1.1-1.21.3-2.32.22.32.3-1.72.0-2.22.11.9
Patch foraging total patch changes 24 sec0.61.02.8-0.1-0.10.70.70.70.11.01.0-0.70.40.50.9-0.9-1.00.6-1.50.81.71.6-0.91.5-1.51.40.6
Patch foraging total patch changes 6 sec1.11.74.6-0.7-0.30.70.70.2-0.01.90.6-0.6-0.1-0.00.8-0.8-0.91.0-2.11.82.12.1-1.41.6-1.91.71.5
Patch foraging time to switch 0 sec1.12.27.61.61.9-2.7-2.70.8-2.1-1.10.5-1.1-2.7-2.80.7-0.8-0.61.41.10.1-1.0-1.0-1.0-0.30.9-0.31.1
Patch foraging water rate 0 sec1.43.09.1-2.2-2.23.03.0-0.92.22.2-0.61.12.52.6-0.60.70.4-1.0-2.10.91.92.00.30.8-1.80.9-0.3
Patch foraging water rate 12 sec0.30.62.3-0.6-0.81.51.5-0.01.00.10.00.41.51.5-0.20.30.2-0.8-0.2-0.60.40.40.70.1-0.10.0-1.0
Patch foraging water rate 18 sec0.61.03.70.3-0.20.50.50.20.7-1.40.10.31.41.4-0.40.40.5-1.11.1-1.9-0.9-0.91.4-0.71.0-0.9-1.9
Patch foraging water rate 24 sec1.62.26.3-1.8-2.02.52.5-1.22.11.0-1.11.52.42.4-1.21.31.1-1.7-0.6-0.20.50.51.2-0.3-0.2-0.3-1.3
Patch foraging water rate 6 sec0.30.51.9-0.6-0.81.41.4-0.11.00.4-0.10.31.31.4-0.30.20.2-0.6-0.4-0.30.60.70.30.2-0.10.1-0.4
Seeking ratio, delayed vs. immediate footshock2.73.45.21.61.8-1.4-1.42.1-2.00.22.2-2.1-1.9-1.92.3-2.2-2.22.3-1.11.31.51.6-2.02.2-1.42.11.8
Distance traveled before self-admin0.50.62.31.21.0-0.7-0.70.9-0.8-1.50.6-0.6-0.6-0.50.4-0.4-0.3-0.11.2-1.2-1.0-1.00.1-0.31.0-0.5-0.1
Distance traveled after self-admin0.20.21.00.50.20.10.10.40.1-0.90.2-0.00.40.4-0.00.00.1-0.50.6-1.0-0.6-0.60.5-0.30.4-0.4-0.7
Extensor digitorum longus weight4.015.528.1-5.3-5.25.15.1-5.35.12.7-4.94.84.64.6-4.74.64.4-4.3-0.60.0-0.5-0.53.2-3.00.2-2.5-2.5
Bone: elastic displacement0.20.20.5-0.7-0.70.70.7-0.50.60.6-0.40.50.60.6-0.40.40.4-0.3-0.40.30.30.40.2-0.0-0.20.0-0.2
Bone: elastic work2.33.06.8-2.6-2.52.62.6-2.32.31.9-2.02.02.12.1-1.81.81.7-1.6-1.00.70.60.70.9-0.7-0.3-0.5-0.6
Bone: endosteal estimation0.61.33.1-1.6-1.51.81.8-1.01.31.7-0.70.91.31.3-0.50.60.4-0.5-1.41.01.31.30.20.4-0.90.6-0.1
Bone: endosteal perimeter0.61.32.7-1.3-1.51.51.5-1.31.60.6-1.21.21.61.7-1.21.21.1-1.3-0.2-0.30.00.01.0-0.70.3-0.6-0.9
Epididymis fat weight0.00.00.2-0.1-0.10.20.2-0.10.2-0.2-0.20.10.20.2-0.20.10.2-0.30.2-0.4-0.3-0.1-0.1-0.30.2-0.30.3
Delta time in closed arm before/after self-admin1.11.01.9-0.4-0.70.60.6-0.60.9-0.8-0.81.01.11.1-1.01.01.1-1.41.1-1.2-1.1-1.11.3-1.21.1-1.2-1.2
Delta time in open arm before/after self-admin2.52.54.92.12.1-2.2-2.21.9-2.1-1.01.7-1.9-2.1-2.01.7-1.8-1.71.90.30.10.1-0.0-1.41.00.00.81.0
Diff in mean of infusions in LGA sessions0.10.20.3-0.4-0.50.60.6-0.50.50.2-0.50.40.50.5-0.50.40.4-0.50.0-0.1-0.1-0.10.3-0.40.1-0.3-0.2
Delay discount exponential model param1.82.16.5-1.2-0.81.21.2-0.40.42.50.1-0.10.20.20.5-0.4-0.60.9-2.52.32.42.4-0.91.6-2.21.81.0
Extinction: sum of active levers before priming0.20.31.10.50.5-0.7-0.70.2-0.4-0.7-0.0-0.2-0.4-0.4-0.1-0.00.10.00.9-0.6-0.7-0.70.1-0.51.1-0.5-0.1
Active lever presses in extinction session 60.10.10.2-0.2-0.30.30.3-0.20.20.4-0.20.10.20.2-0.20.10.1-0.1-0.30.20.30.3-0.10.0-0.20.10.2
Bone: final force2.23.66.6-2.4-2.52.22.2-2.62.41.1-2.42.52.12.1-2.32.32.2-2.10.10.0-0.4-0.41.7-1.50.7-1.3-1.5
Bone: final moment1.72.85.1-2.2-2.22.02.0-2.32.11.1-2.12.21.91.8-2.02.02.0-1.8-0.00.1-0.3-0.31.5-1.20.5-1.1-1.2
Food consumed during 24 hour testing period0.40.61.9-0.5-0.30.50.5-0.10.11.10.2-0.10.00.00.4-0.3-0.40.6-1.41.11.41.4-0.60.9-1.20.90.7
Glucose0.91.33.31.81.5-1.8-1.81.2-1.3-1.80.8-0.9-1.2-1.20.6-0.7-0.50.61.4-1.1-1.2-1.1-0.0-0.31.2-0.5-0.2
Heart weight0.91.33.2-0.5-1.01.01.0-0.61.4-0.7-0.71.11.81.8-1.01.11.1-1.40.9-1.4-0.8-0.71.5-1.01.0-1.1-1.8
Delay discount hyperbolic model param1.71.96.1-1.1-0.81.21.2-0.30.32.40.2-0.10.20.20.5-0.5-0.60.8-2.52.22.32.3-0.91.6-2.21.70.9
Intermittent access intake day 1-15 change0.61.23.6-1.4-1.31.51.5-0.91.01.9-0.60.70.80.8-0.40.50.3-0.2-1.61.51.41.3-0.50.6-1.40.70.7
Intermittent access intake escalation0.51.13.3-1.4-1.21.41.4-0.90.91.8-0.60.70.80.7-0.30.40.3-0.2-1.61.41.31.3-0.50.6-1.40.70.7
Intermittent access intake escalation 20.40.41.1-0.3-0.10.30.30.1-0.10.90.3-0.2-0.1-0.10.4-0.3-0.40.5-1.01.01.00.9-0.90.8-1.00.90.9
Intermitt. access day 1 inactive lever presses0.10.51.4-0.4-0.40.60.6-0.00.21.10.2-0.00.20.20.3-0.2-0.40.3-1.21.01.21.1-0.00.9-1.20.9-0.1
Intermitt. access day 15 inactive lever presses0.61.22.70.20.7-0.8-0.80.4-1.11.10.5-0.9-1.6-1.60.9-1.0-0.91.5-1.11.61.11.0-1.41.0-1.11.21.6
Intermitt. access escalation Index0.20.21.20.50.3-0.2-0.20.4-0.0-1.00.3-0.20.30.30.0-0.1-0.0-0.30.8-1.1-0.7-0.60.4-0.30.7-0.5-0.5
Intermittent access day 1 total infusions0.50.83.01.30.5-0.7-0.70.6-0.1-1.70.4-0.20.30.3-0.00.00.1-0.31.3-1.7-1.2-1.21.1-0.61.0-0.8-1.5
Intermittent access day 15 total infusions0.20.20.80.1-0.40.30.3-0.10.6-0.3-0.20.40.80.8-0.30.40.4-0.40.2-0.6-0.3-0.30.8-0.30.1-0.4-0.9
Intermittent access terminal intake (last 3 days)0.10.10.40.2-0.10.00.0-0.00.2-0.4-0.10.20.40.4-0.20.20.2-0.20.3-0.5-0.4-0.30.6-0.30.2-0.3-0.7
Intermittent access total infusions0.50.51.40.70.1-0.4-0.4-0.00.1-1.1-0.20.30.30.3-0.40.40.5-0.41.1-1.2-1.1-1.11.0-0.80.9-0.9-1.1
Intermittent access day 1 locomotion0.81.03.61.40.8-1.0-1.00.8-0.3-1.90.4-0.40.00.00.0-0.10.0-0.21.6-1.9-1.4-1.40.7-0.81.3-1.0-1.0
Intermittent access day 15 total locomotion0.40.72.20.1-0.60.80.8-0.01.0-0.7-0.10.51.51.5-0.50.50.5-1.00.6-1.4-0.5-0.61.1-0.50.5-0.7-1.4
Intermittent access total locomotion0.60.73.00.90.2-0.3-0.30.40.2-1.50.10.00.60.6-0.30.20.3-0.51.3-1.7-1.2-1.10.9-0.81.1-0.9-1.2
Intermittent access standard deviation0.61.23.8-0.4-0.00.10.10.0-0.41.70.3-0.4-0.8-0.80.6-0.6-0.71.1-1.72.01.61.5-1.11.2-1.71.41.2
Left kidney weight5.324.857.0-7.5-7.16.86.8-7.06.35.8-6.26.05.35.2-5.45.45.0-4.4-3.02.71.51.72.6-2.3-1.5-1.5-1.3
Right kidney weight4.420.146.6-6.8-6.46.06.0-6.55.75.3-5.75.54.64.6-4.95.04.6-4.0-2.62.51.31.52.3-2.2-1.2-1.4-1.1
Cocaine induced anxiety0.40.52.10.40.2-0.4-0.4-0.10.0-1.1-0.30.20.10.1-0.50.40.5-0.51.3-1.2-1.1-1.10.4-1.01.4-1.1-0.4
Post-drug Anxiety2.62.86.92.01.9-2.6-2.60.8-1.7-2.50.3-0.8-1.9-1.90.2-0.4-0.10.52.5-1.6-2.2-2.2-0.0-1.32.6-1.40.2
Baseline Anxiety1.82.06.31.91.9-2.5-2.51.1-2.0-1.40.9-1.2-2.3-2.31.0-1.0-0.81.41.2-0.2-0.9-0.9-0.5-0.01.1-0.10.5
Tail length6.424.947.0-6.6-6.86.16.1-6.96.43.6-6.46.45.75.6-6.06.05.8-5.4-0.70.5-0.6-0.54.0-3.70.7-3.1-3.0
Length with tail11.349.397.7-9.8-9.78.88.8-9.99.16.0-9.18.97.87.7-8.38.48.0-7.2-1.91.60.00.25.2-4.80.1-3.9-3.6
Length without tail5.919.046.6-6.8-6.25.85.8-6.35.45.6-5.55.24.34.2-4.74.74.3-3.5-3.03.01.71.91.9-1.8-1.5-1.0-0.7
Times rat made contact with spout0.91.11.8-1.0-1.21.01.0-1.31.20.2-1.21.31.21.2-1.21.31.2-1.10.3-0.4-0.4-0.41.3-1.00.8-0.9-1.2
Lifetime Intake0.30.41.21.00.5-0.9-0.90.3-0.3-1.10.1-0.1-0.2-0.2-0.10.00.10.10.9-0.9-1.0-0.90.6-0.60.7-0.7-0.7
Liver weight, left2.94.714.8-3.1-2.53.13.1-1.91.93.8-1.21.41.61.6-0.70.80.5-0.4-3.32.92.82.8-0.41.2-2.81.50.8
Liver weight, right1.42.46.1-2.5-2.22.32.3-2.21.92.3-1.81.71.41.4-1.51.51.3-1.1-1.31.30.90.90.3-0.4-0.7-0.10.2
Locomotor activity2.94.69.7-1.9-2.52.32.3-2.02.8-0.0-2.02.43.13.1-2.32.42.3-2.80.7-1.5-1.1-1.12.5-1.80.7-1.8-2.5
Locomotor testing distance0.50.92.3-1.2-1.41.31.3-0.91.41.0-0.70.91.51.5-0.70.80.6-0.9-0.70.30.40.50.5-0.0-0.60.1-0.4
Locomotor testing rearing0.30.71.4-0.10.20.10.10.5-0.31.00.7-0.7-0.3-0.30.8-0.8-0.90.7-1.11.01.21.2-1.11.1-1.01.21.1
Locomotion in novel chamber0.81.13.6-1.0-1.41.61.6-0.61.60.3-0.51.01.91.9-0.80.90.8-1.0-0.3-0.50.20.21.1-0.2-0.2-0.3-1.4
Locomotion in novel chamber post-restriction1.82.97.0-1.5-2.02.12.1-1.62.30.1-1.51.92.62.7-1.71.81.7-2.20.4-1.2-0.6-0.62.0-1.20.5-1.3-2.0
Fecal boli incidents, locomotor time 11.62.34.2-1.6-1.91.91.9-1.72.00.4-1.71.82.02.0-1.71.81.7-1.90.2-0.6-0.5-0.21.6-1.20.4-1.2-1.5
Change in fecal boli incidents, locomotor task0.40.41.20.30.5-0.8-0.80.3-0.80.30.3-0.4-1.1-1.10.5-0.5-0.50.9-0.30.90.40.2-0.90.5-0.20.51.0
Time >=10cm from walls, locomotor time 11.11.12.51.51.3-1.6-1.60.8-1.2-1.60.3-0.7-1.3-1.30.3-0.4-0.20.31.5-1.0-1.3-1.50.1-0.71.1-0.8-0.1
Bouts of movement, locomotor time 11.01.22.3-1.4-1.51.51.5-1.41.50.8-1.21.31.51.5-1.21.21.1-1.2-0.3-0.00.00.10.7-0.70.0-0.6-0.5
Total resting periods, locomotor time 11.11.22.3-1.3-1.51.41.4-1.41.50.6-1.31.31.51.5-1.31.31.2-1.3-0.1-0.2-0.2-0.10.8-0.80.1-0.7-0.6
Rest time, locomotor task time 10.91.22.5-1.4-1.51.31.3-1.61.40.9-1.51.41.21.1-1.41.31.3-1.1-0.30.2-0.10.10.6-0.90.1-0.7-0.3
Distance moved, locomotor task time 10.30.41.60.80.6-0.7-0.70.7-0.4-1.30.5-0.4-0.1-0.10.3-0.2-0.2-0.11.0-1.0-0.7-1.20.3-0.20.7-0.4-0.5
Vertical activity count, locomotor time 10.20.41.0-0.4-0.40.60.6-0.10.6-0.6-0.20.50.90.9-0.50.50.5-0.90.6-0.9-0.5-1.00.7-0.50.6-0.6-0.8
Time >=10cm from walls, locomotor time 20.60.82.2-0.4-0.5-0.1-0.1-1.10.4-0.2-1.40.90.0-0.0-1.21.11.2-0.91.0-0.4-1.2-1.40.9-1.51.1-1.3-0.5
Bouts of movement, locomotor time 20.61.02.0-1.4-1.31.41.4-1.21.40.7-1.11.11.31.4-1.11.11.0-1.2-0.4-0.10.0-0.00.4-0.7-0.4-0.6-0.2
Total resting periods, locomotor time 20.40.81.9-1.4-1.21.31.3-1.11.20.9-1.00.91.11.1-0.90.90.8-0.9-0.60.20.30.20.0-0.4-0.6-0.30.1
Rest time, locomotor task time 20.10.20.70.60.5-0.4-0.40.4-0.5-0.20.3-0.5-0.5-0.50.3-0.4-0.30.40.1-0.1-0.00.2-0.80.10.20.10.9
Distance moved, locomotor task time 20.10.10.4-0.5-0.40.40.4-0.20.40.4-0.10.30.40.4-0.10.20.1-0.2-0.40.30.30.10.40.2-0.60.2-0.5
Vertical activity count, locomotor time 21.31.94.5-2.1-1.92.12.1-1.41.81.2-1.11.51.81.8-1.11.31.1-1.4-0.80.40.50.51.2-0.2-0.8-0.2-1.2
Light reinforcement 10.61.65.01.41.0-1.4-1.40.5-0.6-2.20.1-0.2-0.4-0.4-0.10.10.3-0.32.2-1.9-2.0-1.90.8-1.22.1-1.4-1.0
Light reinforcement 20.20.30.50.70.5-0.6-0.60.6-0.6-0.00.7-0.6-0.5-0.50.7-0.6-0.60.6-0.10.30.30.3-0.40.6-0.20.60.3
Bone: marrow area0.61.23.0-1.5-1.41.71.7-1.01.31.7-0.60.81.21.3-0.50.50.4-0.4-1.51.11.41.40.10.5-1.00.6-0.1
Bone: maximum diameter0.91.63.6-1.8-1.81.61.6-1.91.61.2-1.71.61.31.3-1.51.51.5-1.3-0.40.40.10.10.8-0.9-0.0-0.7-0.5
Bone: maximum force1.73.05.4-2.3-2.32.22.2-2.22.31.2-2.12.12.12.1-2.02.01.9-1.9-0.20.1-0.2-0.11.4-1.20.3-1.0-1.2
Bone: maximum moment1.32.34.4-2.1-2.12.12.1-2.02.01.2-1.81.91.91.9-1.71.81.6-1.7-0.30.2-0.00.01.2-0.90.2-0.8-1.0
Mean time between licks in bursts0.71.73.61.81.7-1.6-1.61.9-1.6-1.01.8-1.7-1.2-1.21.6-1.6-1.61.30.1-0.30.20.2-0.81.1-0.50.90.4
Mean num. licks in bursts0.10.20.60.20.1-0.2-0.2-0.20.0-0.6-0.40.1-0.0-0.0-0.40.30.4-0.40.7-0.7-0.8-0.80.2-0.80.8-0.80.0
Cd content in liver0.80.93.10.4-0.30.30.30.10.7-1.4-0.00.51.31.3-0.50.60.5-1.01.2-1.8-1.1-1.11.4-0.70.9-0.9-1.7
Co content in liver1.51.86.0-0.8-0.41.01.00.20.21.90.7-0.40.20.20.9-0.7-0.90.8-2.31.82.22.2-1.11.8-2.51.91.0
Cu content in liver0.10.10.30.50.3-0.4-0.40.5-0.30.00.4-0.4-0.2-0.20.4-0.4-0.40.5-0.20.10.30.4-0.40.40.10.40.5
Fe content in liver0.91.11.8-0.5-0.80.90.9-0.81.1-0.5-1.00.91.31.3-1.21.01.1-1.30.9-1.3-0.9-0.91.1-1.21.2-1.2-1.1
K content in liver0.10.10.7-0.00.1-0.3-0.3-0.3-0.1-0.0-0.40.1-0.3-0.3-0.30.20.20.00.40.0-0.3-0.3-0.1-0.40.9-0.30.4
Mg content in liver0.20.20.8-0.7-0.70.40.4-0.80.50.9-0.70.60.20.2-0.50.50.5-0.1-0.40.70.30.30.0-0.10.1-0.00.3
Mn content in liver0.30.40.70.30.5-0.5-0.50.5-0.70.20.6-0.6-0.7-0.70.7-0.7-0.70.8-0.40.60.60.6-0.70.7-0.20.70.8
Na content in liver0.50.51.2-1.0-0.90.70.7-1.10.80.7-1.10.90.50.5-0.90.90.9-0.6-0.10.3-0.1-0.10.4-0.60.3-0.5-0.2
Rb content in liver2.02.45.72.42.2-2.2-2.22.0-1.9-1.81.7-1.8-1.7-1.61.5-1.6-1.41.31.0-0.9-0.6-0.6-1.00.50.70.30.9
Se content in liver1.41.74.5-0.7-0.70.10.1-1.60.7-0.4-1.91.30.30.3-1.81.51.7-1.31.4-0.9-1.7-1.60.9-2.11.9-1.9-0.5
Sr content in liver0.60.51.6-0.7-0.50.70.7-0.30.31.20.10.10.20.20.2-0.1-0.20.3-1.31.21.21.2-0.30.8-1.30.90.3
Zn content in liver2.22.57.4-2.3-2.22.22.2-1.71.82.7-1.31.31.51.5-1.01.00.8-0.5-2.01.81.71.7-0.00.4-1.20.70.4
Bone: minimum diameter0.00.00.10.10.00.00.00.10.0-0.20.10.00.10.10.1-0.0-0.0-0.00.0-0.20.00.00.20.0-0.10.0-0.3
Time in familiar zone, hab. session 11.81.73.00.40.9-0.7-0.70.9-1.21.01.1-1.2-1.4-1.41.3-1.3-1.41.6-1.41.61.41.4-1.71.5-1.71.61.7
Time in novel zone, hab. session 11.01.01.8-0.6-0.90.60.6-1.01.0-0.3-1.11.11.01.0-1.21.21.2-1.20.8-0.8-0.9-0.91.3-1.11.1-1.1-1.3
Total zone transitions, hab. session 10.81.14.41.71.2-1.2-1.21.2-0.8-2.11.0-0.8-0.3-0.30.6-0.5-0.40.11.6-1.8-1.2-1.20.4-0.31.3-0.6-0.7
Total locomotion distance, hab. session 10.50.72.41.10.9-1.0-1.00.6-0.6-1.50.4-0.4-0.4-0.40.1-0.2-0.1-0.01.3-1.3-1.2-1.10.2-0.61.1-0.7-0.3
Locomotion velocity, hab. session 10.91.34.61.71.4-1.5-1.51.1-1.0-2.10.8-0.8-0.7-0.60.5-0.5-0.40.11.7-1.7-1.4-1.40.2-0.51.3-0.8-0.3
Time in familiar zone, hab. session 20.20.20.80.10.3-0.5-0.50.0-0.50.30.1-0.3-0.8-0.80.2-0.3-0.20.5-0.30.60.20.2-0.70.2-0.60.30.9
Time in novel zone, hab. session 20.20.20.90.60.2-0.1-0.10.40.0-0.90.3-0.10.30.30.0-0.00.0-0.30.7-1.0-0.5-0.50.7-0.20.8-0.4-0.9
Total zone transitions, hab. session 20.20.30.9-0.3-0.60.50.5-0.40.7-0.2-0.40.60.80.8-0.50.60.5-0.60.3-0.5-0.3-0.30.9-0.40.3-0.4-1.0
Total locomotion distance, hab. session 20.10.20.70.50.3-0.3-0.30.4-0.1-0.80.3-0.10.10.10.1-0.0-0.0-0.10.6-0.8-0.5-0.50.5-0.20.4-0.3-0.7
Locomotion velocity, hab. session 20.10.10.70.50.3-0.3-0.30.4-0.1-0.80.3-0.10.20.20.1-0.1-0.0-0.10.6-0.7-0.5-0.50.5-0.10.4-0.3-0.6
Novel to familiar place preference ratio0.10.10.40.2-0.00.00.00.00.1-0.5-0.00.20.30.3-0.10.20.2-0.30.4-0.5-0.4-0.30.5-0.20.4-0.3-0.6
Novelty place preference0.10.10.50.50.3-0.3-0.30.3-0.2-0.70.3-0.10.00.00.1-0.1-0.1-0.10.5-0.6-0.4-0.40.3-0.10.4-0.2-0.5
Time in novel zone, NPP test0.10.10.40.30.1-0.1-0.10.10.0-0.60.10.10.10.1-0.00.10.1-0.20.5-0.5-0.4-0.40.4-0.20.4-0.3-0.6
Total zone transitions, NPP test0.20.30.90.0-0.30.20.2-0.20.5-0.5-0.30.50.70.7-0.50.50.5-0.60.6-0.8-0.6-0.61.0-0.60.7-0.6-1.0
Total locomotion distance, NPP test0.71.02.70.50.1-0.4-0.4-0.10.2-1.4-0.40.40.40.4-0.70.60.7-0.81.6-1.6-1.5-1.51.2-1.31.5-1.4-1.2
Locomotion velocity, NPP test0.81.13.30.4-0.1-0.0-0.0-0.20.5-1.5-0.50.50.80.8-0.80.70.8-1.11.5-1.8-1.5-1.51.3-1.31.5-1.4-1.4
Intraocular pressure1.01.43.1-1.6-1.71.81.8-1.41.71.3-1.21.21.61.6-1.21.11.0-1.0-0.80.30.50.50.5-0.4-0.5-0.3-0.3
Delta distance traveled before/after self-admin0.30.31.1-0.6-0.70.60.6-0.30.50.9-0.10.30.60.6-0.10.10.0-0.0-1.00.70.90.80.00.5-1.00.5-0.1
Delta ambulatory time before/after self-admin0.30.31.10.30.2-0.3-0.30.5-0.30.40.6-0.5-0.2-0.20.6-0.6-0.70.7-0.80.60.80.8-0.50.8-1.00.80.2
Parametrial fat weight0.10.21.0-0.30.1-0.3-0.3-0.4-0.40.7-0.4-0.0-1.0-1.0-0.1-0.00.10.3-0.30.90.10.1-0.6-0.1-0.30.10.9
Pavlov. Cond. lever latency1.41.74.4-2.1-1.91.81.8-1.71.62.0-1.41.41.21.2-1.11.21.0-0.8-1.11.31.01.00.3-0.1-0.30.1-0.1
Pavlov. Cond. magazine entry latency0.60.71.3-0.6-0.80.70.7-0.91.0-0.3-0.91.01.01.0-1.01.01.0-1.10.5-0.8-0.8-0.80.8-1.00.0-1.0-0.7
Pavlov. Cond. change in total contacts0.70.72.40.80.6-1.0-1.00.1-0.4-1.5-0.20.0-0.4-0.4-0.30.30.4-0.41.4-1.2-1.6-1.50.3-1.10.9-1.2-0.2
Pavlov. Cond. index score0.20.30.90.50.3-0.4-0.40.1-0.1-1.0-0.10.0-0.0-0.0-0.20.20.3-0.30.8-1.0-0.9-1.00.3-0.70.3-0.7-0.3
Pavlov. Cond. latency score0.40.51.70.80.6-0.7-0.70.3-0.3-1.30.1-0.2-0.2-0.2-0.10.00.1-0.21.0-1.2-1.2-1.20.3-0.70.4-0.8-0.4
Pavlov. Cond. lever contacts1.11.33.31.81.7-1.7-1.71.4-1.4-1.81.1-1.2-1.2-1.20.9-1.0-0.80.71.1-1.2-1.0-1.0-0.3-0.10.4-0.30.1
Pavlov. Cond. magazine entry number0.70.81.50.40.8-0.6-0.60.8-1.00.50.9-1.0-1.1-1.11.1-1.0-1.11.2-0.71.11.01.0-0.91.2-0.31.20.8
Pavlov. Cond. intertrial magazine entries0.70.92.11.21.2-1.0-1.01.4-1.1-0.61.4-1.2-0.9-0.91.2-1.2-1.21.00.1-0.10.30.3-0.70.90.10.80.4
Pavlov. Cond. lever-magazine prob. diff.0.20.20.70.40.3-0.4-0.40.0-0.1-0.8-0.10.0-0.1-0.1-0.20.20.2-0.30.7-0.8-0.8-0.80.1-0.60.2-0.7-0.1
Pavlov. Cond. response bias0.40.51.1-0.1-0.40.20.2-0.50.6-0.7-0.60.60.70.7-0.70.70.7-0.90.7-1.0-0.9-0.90.6-0.90.3-1.0-0.6
Pavlov. Cond. lever latency0.81.24.2-0.6-0.10.40.40.1-0.31.60.4-0.4-0.5-0.50.7-0.6-0.70.9-1.71.81.51.5-1.21.3-2.01.41.3
Pavlov. Cond. magazine entry latency1.51.86.01.71.2-1.7-1.70.7-0.8-2.40.3-0.4-0.6-0.6-0.0-0.00.2-0.32.3-2.1-2.1-2.00.6-1.22.0-1.4-0.8
Pavlov. Cond. change in total contacts0.60.93.10.70.1-0.3-0.30.20.3-1.6-0.10.30.70.7-0.40.40.5-0.81.5-1.8-1.3-1.31.1-0.91.6-1.1-1.3
Pavlov. Cond. index score1.11.55.01.40.7-1.0-1.00.5-0.2-2.20.2-0.10.10.1-0.20.20.3-0.62.1-2.2-1.8-1.81.0-1.12.0-1.4-1.3
Pavlov. Cond. latency score1.11.44.71.30.7-1.1-1.10.5-0.3-2.20.1-0.10.00.0-0.20.20.3-0.52.0-2.1-1.8-1.71.0-1.22.0-1.4-1.2
Pavlov. Cond. lever contacts1.01.45.00.80.2-0.6-0.6-0.00.2-1.8-0.40.40.40.5-0.70.60.8-0.92.0-2.0-1.7-1.71.2-1.42.2-1.5-1.4
Pavlov. Cond. magazine entry number1.21.55.7-1.7-1.11.51.5-0.90.72.4-0.50.50.40.4-0.20.20.00.2-2.02.01.71.6-0.60.9-1.81.10.9
Pavlov. Cond. intertrial magazine entries0.50.82.0-1.2-1.21.41.4-1.01.20.8-0.80.91.21.2-0.80.80.7-0.8-0.50.20.30.30.6-0.2-0.4-0.1-0.5
Pavlov. Cond. lever-magazine prob. diff.1.31.75.81.40.7-1.1-1.10.6-0.2-2.40.2-0.10.20.2-0.30.20.4-0.72.2-2.4-1.9-1.91.1-1.22.2-1.5-1.4
Pavlov. Cond. response bias1.52.16.71.30.6-1.0-1.00.4-0.0-2.5-0.10.10.40.4-0.50.40.6-1.02.5-2.6-2.2-2.11.3-1.52.6-1.7-1.6
Time in closed arm before self-admin1.21.53.4-1.7-1.81.71.7-1.31.71.3-1.11.41.81.8-1.11.21.0-1.0-0.90.40.60.60.9-0.2-0.6-0.1-1.0
Time in closed arm after self-admin2.32.56.3-1.6-2.02.02.0-1.42.20.3-1.21.72.52.5-1.51.61.5-2.00.1-0.8-0.3-0.21.8-0.90.1-0.9-2.0
Time in open arm before self-admin0.50.61.40.2-0.20.40.4-0.20.5-1.0-0.40.50.60.6-0.60.60.6-1.01.1-1.2-1.1-1.01.0-0.91.0-1.0-0.9
Time in open arm after self-admin1.01.12.81.41.5-1.5-1.51.0-1.6-0.70.9-1.2-1.7-1.70.9-1.1-0.91.10.50.0-0.3-0.3-1.00.30.30.30.9
Bone: periosteal estimation1.22.64.9-2.1-2.22.12.1-2.12.11.2-1.92.02.02.0-1.81.91.8-1.7-0.30.10.00.01.3-1.10.2-0.9-1.1
Bone: periosteal perimeter1.12.03.0-1.0-1.31.11.1-1.41.5-0.3-1.51.51.61.6-1.71.61.6-1.71.0-1.2-1.1-1.11.5-1.61.4-1.6-1.4
Bone: post-yield work0.10.20.5-0.5-0.50.70.7-0.40.60.4-0.30.30.60.6-0.40.30.3-0.4-0.2-0.00.20.10.1-0.1-0.1-0.1-0.1
Progressive ratio test 1 active lever presses0.91.12.0-0.9-1.41.01.0-1.41.40.4-1.31.41.31.3-1.31.31.3-1.10.1-0.3-0.4-0.41.3-0.90.2-0.8-1.2
Progressive ratio test 1 breakpoint0.91.12.0-0.9-1.41.01.0-1.41.40.4-1.31.41.31.3-1.31.31.3-1.10.1-0.3-0.4-0.41.3-0.90.2-0.9-1.2
Progressive ratio test 1 inactive lever presses0.50.71.5-0.8-1.11.21.2-0.51.11.1-0.30.61.21.2-0.30.40.2-0.4-1.00.60.90.90.70.4-0.90.5-0.8
Progressive ratio test 2 active lever presses0.91.12.6-1.0-1.41.31.3-1.11.50.3-0.91.31.61.6-1.11.21.1-1.10.0-0.4-0.1-0.21.3-0.60.2-0.6-1.3
Progressive ratio test 2 breakpoint0.91.02.4-0.9-1.31.31.3-1.01.40.3-0.91.21.61.6-1.01.11.0-1.10.1-0.4-0.2-0.31.3-0.60.2-0.6-1.3
Progressive ratio test 2 inactive lever presses1.42.25.6-1.9-2.12.42.4-1.42.01.9-1.01.42.12.1-1.01.10.9-1.0-1.50.81.31.10.80.2-1.20.3-0.7
Incentive Sensitization - Responses0.00.00.10.00.10.10.10.2-0.1-0.10.2-0.10.10.10.2-0.1-0.20.10.1-0.00.10.0-0.00.20.20.2-0.0
Incentive Sensitization - Breakpoint0.00.00.10.10.20.00.00.3-0.1-0.20.3-0.20.00.00.3-0.2-0.20.10.1-0.10.10.0-0.10.20.30.20.0
Sum of active levers in priming session hrs 5-60.10.10.5-0.10.1-0.3-0.3-0.3-0.20.2-0.40.1-0.6-0.6-0.20.10.20.20.20.3-0.2-0.2-0.3-0.30.5-0.20.7
Progressive ratio0.40.61.11.01.0-0.8-0.81.1-1.0-0.61.0-1.0-0.9-0.91.0-0.9-0.90.70.0-0.00.10.0-0.50.6-0.30.50.3
Food seeking constrained by brief footshock3.23.96.01.11.6-1.1-1.11.8-1.91.02.1-2.2-1.9-1.92.3-2.3-2.42.4-1.81.92.12.1-2.42.4-2.12.42.2
Seeking ratio, punishment vs. effort0.30.41.5-1.0-0.80.80.8-0.70.61.2-0.50.50.50.5-0.40.40.3-0.1-0.90.90.80.8-0.10.2-0.50.30.3
Retroperitoneal fat weight0.20.71.80.40.7-1.2-1.2-0.4-0.8-0.5-0.6-0.1-1.3-1.4-0.40.10.30.20.9-0.1-1.0-0.9-0.6-1.01.2-0.91.1
Reaction time number correct0.40.71.9-0.9-0.91.31.3-0.30.81.2-0.00.31.01.0-0.00.1-0.1-0.1-1.30.81.31.4-0.00.7-1.00.8-0.1
Reaction time mean minus median1.94.810.40.1-0.6-0.0-0.0-1.31.2-2.4-1.81.61.31.3-2.12.02.2-2.43.0-3.1-3.2-3.22.5-3.02.8-3.1-2.5
Reaction time mean minus median AUC0.71.85.80.80.2-0.5-0.5-0.10.3-2.1-0.30.40.70.7-0.80.70.8-1.22.2-2.4-2.1-2.11.5-1.61.8-1.8-1.7
Reaction time num false alarms0.81.24.00.60.0-0.2-0.20.10.4-1.7-0.30.40.80.8-0.60.60.7-1.11.7-2.0-1.6-1.51.3-1.21.4-1.4-1.5
Reaction time num false alarms AUC0.50.72.60.3-0.10.00.0-0.00.5-1.3-0.30.40.80.8-0.60.50.6-1.01.2-1.6-1.2-1.11.1-1.01.0-1.1-1.2
Reaction time trials correct on left0.40.71.9-0.9-0.91.31.3-0.30.81.2-0.00.31.01.0-0.00.1-0.1-0.1-1.30.81.31.4-0.00.7-1.00.8-0.1
Reaction time trials on left0.40.71.6-0.8-0.91.31.3-0.30.81.2-0.10.31.01.0-0.00.1-0.0-0.1-1.20.71.21.30.00.7-0.90.7-0.1
Reaction time mean1.72.78.92.11.8-2.3-2.31.0-1.4-3.00.6-0.7-1.2-1.30.3-0.3-0.10.12.6-2.2-2.4-2.40.6-1.22.0-1.5-0.9
Reaction time mean AUC1.72.78.72.21.8-2.3-2.31.1-1.4-2.90.7-0.8-1.2-1.20.4-0.4-0.20.22.5-2.2-2.3-2.30.5-1.11.8-1.3-0.8
Median of all reaction times2.23.17.52.52.4-2.7-2.71.7-2.2-2.71.4-1.5-2.1-2.11.1-1.2-0.91.12.0-1.5-1.7-1.6-0.2-0.31.3-0.5-0.1
Reaction time omissions0.71.03.31.10.7-1.0-1.00.3-0.4-1.80.1-0.1-0.2-0.2-0.20.10.3-0.41.6-1.7-1.6-1.50.8-1.01.2-1.2-0.9
Reaction time false alarm rate0.91.33.90.70.2-0.5-0.50.00.2-1.8-0.30.30.40.4-0.70.60.7-1.01.8-2.0-1.9-1.81.1-1.41.4-1.5-1.2
Reaction time premature initiation rate0.60.82.0-0.1-0.20.30.3-0.30.5-1.2-0.50.60.60.6-0.80.80.8-1.11.3-1.4-1.4-1.31.1-1.20.9-1.2-1.3
Reaction time premature initiations0.30.51.2-0.4-0.50.70.7-0.30.7-0.5-0.40.60.90.9-0.60.60.6-0.90.5-0.9-0.6-0.61.0-0.70.4-0.7-1.1
Std. dev. reaction times1.52.87.81.00.4-1.1-1.1-0.30.0-2.6-0.70.50.20.2-1.10.91.2-1.22.7-2.6-2.8-2.81.6-2.22.2-2.3-1.8
Reaction time trials completed0.40.71.6-0.8-0.91.31.3-0.30.81.2-0.10.31.01.0-0.00.1-0.0-0.1-1.20.71.21.30.00.7-0.90.7-0.1
Reaction time trials AUC0.30.51.5-0.6-0.71.11.1-0.10.71.00.10.20.90.90.1-0.0-0.2-0.0-1.10.61.21.2-0.00.7-0.90.7-0.1
Run reversals in cocaine runway, females0.90.91.50.91.2-1.0-1.01.2-1.2-0.21.0-1.2-1.2-1.21.1-1.2-1.11.1-0.10.30.30.4-1.00.8-0.10.70.9
Run reversals in cocaine runway, males0.20.20.50.2-0.00.40.40.50.2-0.10.7-0.30.60.60.4-0.4-0.4-0.0-0.3-0.30.40.40.10.6-0.40.5-0.5
Latency to leave start box in cocaine runway0.10.10.30.30.2-0.5-0.5-0.1-0.3-0.1-0.20.0-0.5-0.5-0.10.10.10.10.30.1-0.3-0.3-0.0-0.20.4-0.20.0
Latency to leave start box in cocaine runway, F0.10.21.0-0.3-0.3-0.2-0.2-0.6-0.00.8-0.50.4-0.4-0.5-0.20.30.30.1-0.41.00.30.2-0.3-0.0-0.20.10.5
Latency to leave start box in cocaine runway, M0.20.20.80.60.5-0.3-0.30.5-0.3-0.90.4-0.3-0.1-0.00.2-0.2-0.10.10.6-0.8-0.5-0.40.3-0.20.5-0.3-0.6
Std. dev. time between licks in bursts0.30.41.2-0.3-0.60.60.6-0.30.8-0.4-0.30.51.11.1-0.50.60.5-0.90.4-0.9-0.5-0.50.9-0.50.0-0.6-1.0
Total sessions with >9 infusions0.30.30.90.70.6-0.9-0.90.4-0.7-0.00.4-0.5-0.8-0.80.5-0.5-0.50.8-0.10.30.1-0.0-0.50.3-0.40.40.5
Short access day 1 total inactive lever presses0.50.71.9-0.4-0.00.20.20.0-0.21.30.3-0.4-0.5-0.50.5-0.5-0.60.7-1.31.41.31.3-1.01.0-1.31.11.1
Short access day 10 total inactive lever presses1.12.810.4-1.7-1.11.21.2-0.90.43.2-0.40.2-0.2-0.20.2-0.2-0.40.7-2.93.12.62.5-1.31.5-2.61.81.7
Short access day 1 total infusions1.11.42.81.31.4-1.5-1.51.2-1.6-0.21.2-1.4-1.7-1.71.3-1.3-1.31.6-0.30.60.40.4-1.10.9-0.70.91.0
Short access day 10 total infusions0.30.41.01.00.8-1.0-1.00.6-0.8-0.30.5-0.7-0.8-0.80.6-0.6-0.60.80.1-0.0-0.1-0.2-0.50.2-0.20.20.5
Short access total infusions0.81.03.01.41.3-1.7-1.70.8-1.3-0.60.7-1.0-1.5-1.50.8-0.9-0.81.20.30.1-0.3-0.3-0.70.3-0.00.30.7
Short access day 1 locomotion0.80.92.90.90.4-0.6-0.60.2-0.0-1.7-0.10.10.20.2-0.40.30.4-0.61.6-1.7-1.6-1.60.9-1.01.3-1.2-1.1
Short access day 10 total locomotion0.20.51.30.20.10.10.10.5-0.20.70.6-0.6-0.2-0.20.6-0.6-0.70.6-0.90.71.00.9-0.90.9-1.10.90.8
Short access total locomotion0.40.51.51.20.9-1.2-1.20.7-0.8-1.00.5-0.6-0.7-0.70.4-0.5-0.40.40.8-0.7-0.8-0.9-0.1-0.20.4-0.3-0.1
One hour access (0.3 mA shock)0.91.13.7-0.9-1.41.71.7-0.61.50.7-0.40.91.91.9-0.60.70.5-1.0-0.7-0.10.60.71.00.2-0.60.1-1.1
Compulsive drug intake1.31.63.51.51.7-1.3-1.31.9-1.6-0.91.8-1.6-1.3-1.31.6-1.6-1.61.20.2-0.10.30.2-1.01.1-0.00.90.6
One hour access (shock baseline)1.82.85.9-1.3-2.01.81.8-1.72.20.2-1.61.92.42.4-1.81.91.8-2.00.4-1.0-0.7-0.62.0-1.40.6-1.3-2.0
Social response proportion6.47.311.2-2.5-3.02.62.6-3.23.10.1-3.23.33.02.9-3.23.33.3-3.31.2-1.3-1.7-1.73.2-2.71.7-2.6-3.0
Social responses2.43.16.2-1.6-2.12.02.0-1.82.30.1-1.72.02.52.5-1.92.01.9-2.20.5-1.1-0.8-0.82.0-1.50.5-1.4-2.1
Social time1.21.65.92.01.5-1.6-1.61.5-1.1-2.41.2-0.9-0.7-0.60.8-0.7-0.60.31.7-1.8-1.5-1.50.4-0.31.0-0.5-0.9
Soleus weight0.92.66.2-2.4-2.22.52.5-2.02.11.6-1.81.72.02.0-1.61.61.5-1.6-0.80.40.50.50.8-0.7-0.3-0.5-0.5
Bone: stiffness1.22.03.2-1.0-1.41.21.2-1.31.6-0.4-1.41.61.71.7-1.61.61.6-1.81.1-1.2-1.2-1.21.8-1.51.3-1.5-1.8
Tibialis anterior weight5.317.833.2-5.6-5.55.25.2-5.85.32.8-5.55.34.64.6-5.25.15.0-4.7-0.20.0-0.9-0.83.4-3.50.9-3.0-2.6
Time to tail flick, vehicle, before self-admin1.01.03.10.90.8-1.0-1.00.2-0.6-1.6-0.2-0.0-0.7-0.8-0.30.20.4-0.21.8-1.2-1.7-1.70.6-1.11.7-1.2-0.7
Time to tail flick, vehicle, after self-admin0.30.40.90.1-0.2-0.1-0.1-0.20.4-0.7-0.40.40.50.5-0.50.50.5-0.60.8-0.9-0.8-0.80.8-0.70.9-0.7-0.9
Time to tail flick, test, before self-admin1.01.12.4-1.4-1.51.31.3-1.51.41.2-1.21.31.21.2-1.11.21.0-0.9-0.60.60.40.30.8-0.4-0.3-0.2-0.7
Time to tail flick, test, after self-admin0.20.20.40.40.4-0.6-0.60.1-0.4-0.6-0.0-0.1-0.6-0.6-0.0-0.00.10.10.6-0.3-0.6-0.60.0-0.40.5-0.40.0
Delta time to tail flick, vehicle, before/after SA0.00.00.10.1-0.00.00.00.30.10.00.3-0.20.30.30.2-0.2-0.30.1-0.2-0.10.30.3-0.10.3-0.20.30.0
Delta time to tail flick, test, before/after SA1.01.02.01.21.4-1.1-1.11.3-1.4-0.71.2-1.3-1.3-1.31.1-1.2-1.11.00.2-0.1-0.0-0.0-1.00.6-0.20.50.9
Tibia length2.67.217.2-4.2-3.83.43.4-4.03.23.2-3.63.52.42.3-3.03.12.9-2.2-1.51.80.60.61.6-1.4-1.0-0.9-1.0
Ambulatory time before self-admin0.30.51.70.60.5-0.1-0.10.4-0.2-1.30.1-0.10.00.1-0.10.00.2-0.61.2-1.3-1.1-1.10.4-0.71.1-0.8-0.4
Ambulatory time after self-admin0.10.20.70.70.4-0.2-0.20.6-0.2-0.80.4-0.30.00.00.2-0.2-0.2-0.20.6-0.8-0.5-0.50.2-0.10.3-0.3-0.4
Bone: tissue strength1.41.43.2-0.20.20.10.10.5-0.51.50.8-0.8-0.7-0.71.0-1.0-1.11.2-1.71.71.81.8-1.41.6-1.61.61.5
Total heroin consumption1.82.16.82.21.7-1.8-1.81.5-1.2-2.61.0-1.0-0.8-0.80.6-0.7-0.50.42.1-2.1-1.8-1.70.4-0.61.9-0.9-0.7
Bone: trabecular number1.62.76.8-2.6-2.32.42.4-2.22.02.4-1.91.71.61.6-1.61.51.4-1.2-1.41.31.01.00.3-0.4-0.5-0.10.2
Bone: trabecular spacing2.02.75.22.22.3-2.2-2.22.2-2.1-1.42.1-2.1-1.9-1.91.9-1.9-1.81.70.3-0.3-0.0-0.0-1.31.1-0.50.90.9
Bone: trabecular thickness2.22.86.7-2.6-2.32.42.4-2.32.11.9-2.11.91.81.8-1.91.71.7-1.6-0.90.70.50.50.7-0.9-0.2-0.6-0.3
Bone: trabecular tissue density3.34.910.90.0-0.6-0.2-0.2-1.31.1-2.4-1.81.71.11.1-2.12.12.3-2.23.0-2.9-3.3-3.32.6-3.12.8-3.2-2.6
Water consumed over 24 hours1.41.94.4-2.1-2.02.12.1-1.71.81.8-1.31.51.61.6-1.11.31.1-0.8-1.21.11.11.10.8-0.0-0.50.1-0.6
Number of responses in last shaping day0.20.30.90.90.7-0.9-0.90.5-0.6-0.40.5-0.6-0.6-0.60.4-0.5-0.40.60.2-0.2-0.2-0.2-0.10.10.10.1-0.0