Hub : Genes

Ppp6r3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Ppp6r3 0.09 0.06 2.1e-07 0.07 0.07 0.07 0.07 4.7e-08 2.0e-08 5.9e-08 4.5e-08
2 BLA gene expression Ppp6r3 0.07 0.05 5.7e-03 0.05 0.02 0.02 0.04 1.7e-03 1.8e-02 2.4e-02 4.8e-03
3 NAcc gene expression Ppp6r3 0.04 0.03 8.9e-04 0.03 0.03 0.02 0.03 3.1e-04 6.5e-04 2.4e-03 5.0e-04
4 Brain gene expression Ppp6r3 0.09 0.06 1.4e-05 0.06 0.05 0.04 0.06 4.6e-06 1.2e-05 2.8e-04 5.6e-06
5 IL mRNA stability Ppp6r3 0.23 0.14 3.4e-03 0.1 0.03 0.05 0.06 2.8e-03 5.5e-02 2.5e-02 1.5e-02
6 pVTA gene expression Ppp6r3 0.08 0.06 6.4e-03 0.04 0.04 0.05 0.04 7.3e-03 9.1e-03 4.3e-03 1.0e-02
7 IL gene expression Ppp6r3 0.33 0.17 1.3e-04 0.14 0.16 0.17 0.17 2.5e-04 1.2e-04 6.6e-05 8.1e-05
8 Liver gene expression Ppp6r3 0.1 0.05 3.4e-09 0.03 0.07 0.07 0.06 1.9e-04 7.2e-08 8.4e-08 3.1e-07
9 BLA intron excision ratio chr1_200775836_200807434 0.05 0.04 8.4e-03 0.04 0.02 0.01 0.03 1.9e-03 2.9e-02 5.1e-02 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.21.96.6-0.80.40.50.30.3-1.61.4-2.22.6
Area under the delay curve0.30.31.2-0.1-0.0-0.20.00.0-1.10.5-0.90.9
BMI with tail2.47.713.7-2.82.62.72.42.3-0.33.3-3.73.3
BMI without tail1.63.35.6-1.91.51.71.71.7-0.12.2-2.42.1
Body weight3.313.917.9-4.24.14.24.24.02.54.1-3.32.2
Weight adjusted by age1.31.42.0-1.41.41.31.31.31.31.3-0.90.4
Bone surface2.44.39.0-2.01.71.81.41.5-0.72.5-3.03.0
Bone volume1.11.85.6-0.90.60.70.50.5-1.21.5-2.12.4
Breakpoint value in progressive ratio session1.92.12.8-1.71.71.71.61.61.01.6-1.30.9
Number of licking bursts0.00.00.1-0.10.1-0.1-0.2-0.0-0.20.2-0.30.4
Context. condit. distance diff. score0.70.91.61.1-1.2-1.3-1.1-0.9-1.1-0.70.4-0.1
Locomotion velocity, session 10.00.00.10.00.1-0.1-0.2-0.1-0.2-0.0-0.10.1
Locomotion distance, session 10.81.03.1-0.70.60.40.20.3-0.91.1-1.61.7
Locomotion velocity, session 22.12.53.5-1.91.81.81.61.81.41.7-1.20.6
Locomotion distance, session 20.71.01.7-1.01.10.90.80.7-0.11.1-1.31.2
Locomotion velocity, session 30.60.72.4-0.20.1-0.0-0.1-0.0-1.20.7-1.31.5
Locomotion distance, session 30.00.00.1-0.10.0-0.1-0.10.1-0.30.2-0.30.4
Stereotopy head waving bouts, day 30.50.62.10.2-0.5-0.6-0.3-0.3-1.40.4-0.91.2
Stereotopy head waving duration, day 30.80.92.40.9-1.1-1.2-0.9-1.0-1.6-0.5-0.10.6
Locomotion velocity, session 70.40.41.3-0.2-0.1-0.20.00.3-0.80.7-1.01.2
Locomotion distance, session 70.30.40.7-0.70.50.60.30.80.20.8-0.70.6
Stereotopy head waving bouts, day 70.60.72.40.6-0.6-0.9-0.4-0.8-1.6-0.1-0.61.0
Stereotopy head waving duration, day 71.11.33.4-0.90.80.61.00.6-0.71.3-1.81.8
Locomotion velocity, session 81.41.72.4-1.51.41.41.41.51.01.5-1.10.6
Locomotion distance, session 80.20.40.90.5-0.5-0.6-0.8-0.7-1.0-0.3-0.20.5
Degree of sensitization distance0.30.30.6-0.60.40.60.40.6-0.10.7-0.80.7
Degree of sensitization stereotypy0.40.41.2-0.40.40.20.60.1-0.60.6-1.01.1
Conditioned locomotion1.92.25.8-1.41.71.81.61.52.40.60.3-1.0
Cocaine response after cond. corrected0.10.10.20.3-0.4-0.4-0.3-0.3-0.4-0.20.10.1
Cocaine response after cond. not corrected0.20.20.70.3-0.4-0.4-0.3-0.4-0.9-0.1-0.30.5
Cocaine response before conditioning0.10.10.3-0.20.20.20.1-0.1-0.40.3-0.50.5
Saline control response2.63.44.6-2.12.12.02.12.11.42.1-1.60.9
Bone: connectivity density2.74.29.0-1.91.71.71.41.4-0.82.4-3.03.0
Bone: cortical apparent density0.60.71.1-0.91.01.01.01.01.00.8-0.4-0.0
Bone: cortical area0.30.51.1-0.60.90.90.70.51.10.20.2-0.5
Bone: cortical porosity0.00.00.10.1-0.00.0-0.1-0.2-0.3-0.0-0.20.3
Bone: cortical porosity0.20.30.4-0.60.60.70.60.50.30.5-0.40.3
Bone: cortical thickness3.15.110.0-2.32.92.92.62.23.21.3-0.2-0.9
Bone: cortical thickness1.61.93.1-1.51.71.81.61.41.71.0-0.4-0.2
Bone: cortical tissue density0.70.91.3-1.11.11.11.21.11.10.8-0.4-0.1
Condit. Reinf. active minus inactive responses0.20.20.6-0.10.30.00.2-0.2-0.60.2-0.70.8
Condit. Reinf. active-inactive response ratio0.10.10.40.2-0.1-0.3-0.1-0.4-0.7-0.1-0.30.5
Condit. Reinf. active responses0.00.00.10.10.0-0.10.1-0.4-0.3-0.2-0.10.2
Condit. Reinf. inactive responses0.10.10.10.2-0.2-0.2-0.1-0.30.1-0.30.4-0.3
Incentive salience index mean0.10.10.4-0.10.30.20.2-0.2-0.50.2-0.60.7
Condit. Reinf. lever presses0.00.00.10.10.20.2-0.0-0.20.1-0.30.2-0.2
Condit. Reinf. active minus inactive responses1.01.23.90.9-0.9-1.0-1.1-1.3-2.0-0.5-0.41.0
Condit. Reinf. active-inactive response ratio2.22.34.11.7-1.5-1.6-1.7-2.0-2.0-1.40.40.3
Condit. Reinf. active responses0.60.82.70.1-0.3-0.3-0.4-0.5-1.70.4-1.21.6
Condit. Reinf. inactive responses1.21.42.7-1.20.91.00.91.1-0.21.6-1.61.5
Condit. Reinf. lever presses0.71.02.1-0.90.90.90.60.6-0.41.2-1.51.4
Condit. Reinf. lever reinforcers received0.60.93.0-0.2-0.0-0.1-0.2-0.2-1.50.7-1.41.7
Conditioned reinforcement - actives0.50.51.00.7-0.6-0.6-0.5-0.60.1-0.91.0-0.9
Conditioned reinforcement - inactives5.46.18.12.9-2.8-2.7-2.7-2.7-2.2-2.62.0-1.2
Conditioned locomotion9.010.814.63.7-3.4-3.5-3.5-3.5-1.4-3.83.4-2.6
Patch foraging indifference point 0 sec0.20.20.80.5-0.9-0.7-0.5-0.3-0.6-0.20.2-0.1
Patch foraging indifference point AUC1.01.22.0-1.21.41.31.41.01.40.7-0.3-0.2
Delay disc. indifference point, 0s delay0.70.72.6-0.1-0.00.00.0-0.0-1.60.6-1.21.5
Delay disc. indifference point, 16s delay1.21.22.01.3-1.2-1.4-1.1-1.2-1.2-1.00.6-0.2
Delay disc. indifference point, 2s delay0.30.31.10.5-0.5-0.5-0.5-0.4-1.1-0.1-0.30.6
Delay disc. indifference point, 24s delay0.10.10.3-0.30.30.20.30.30.50.10.2-0.4
Delay disc. indifference point, 4s delay0.10.10.4-0.20.10.00.10.2-0.50.4-0.60.6
Delay disc. indifference point, 8s delay0.30.30.6-0.40.40.10.40.4-0.50.7-0.80.7
Indifference point function ln k3.75.28.12.6-2.7-2.6-2.8-2.3-1.8-2.31.8-1.1
Indifference point function log k3.75.28.12.6-2.7-2.6-2.8-2.3-1.8-2.31.8-1.1
Patch foraging total patch changes 0 sec0.10.10.30.2-0.6-0.3-0.10.10.1-0.10.4-0.4
Patch foraging total patch changes 12 sec2.22.84.6-1.91.71.82.11.91.51.7-1.20.6
Patch foraging total patch changes 18 sec0.40.50.8-0.70.60.70.80.80.30.9-0.70.5
Patch foraging total patch changes 24 sec1.01.22.1-1.21.01.11.41.41.40.9-0.3-0.3
Patch foraging total patch changes 6 sec0.91.42.2-1.30.91.11.31.20.21.5-1.41.1
Patch foraging time to switch 0 sec2.03.16.4-1.61.41.31.51.4-0.62.2-2.52.5
Patch foraging water rate 0 sec4.57.212.62.7-2.5-2.5-2.5-2.30.2-3.23.5-3.3
Patch foraging water rate 12 sec6.710.216.33.4-2.9-3.0-3.2-3.0-0.3-3.94.0-3.4
Patch foraging water rate 18 sec1.72.43.41.7-1.5-1.5-1.8-1.6-0.6-1.81.7-1.2
Patch foraging water rate 24 sec2.73.87.31.9-1.6-1.5-1.9-1.60.4-2.42.7-2.5
Patch foraging water rate 6 sec1.82.75.71.5-1.4-1.2-1.3-1.10.6-2.02.4-2.3
Seeking ratio, delayed vs. immediate footshock0.30.31.2-0.30.10.20.30.2-0.60.6-1.01.1
Distance traveled before self-admin0.10.10.2-0.30.30.30.30.2-0.00.4-0.50.4
Distance traveled after self-admin0.00.00.1-0.00.10.0-0.1-0.00.00.1-0.20.3
Extensor digitorum longus weight5.622.130.0-5.45.55.45.45.44.54.6-3.01.2
Bone: elastic displacement1.11.24.30.5-0.2-0.1-0.3-0.21.3-1.11.8-2.1
Bone: elastic work1.31.74.0-1.31.51.61.31.42.00.70.1-0.8
Bone: endosteal estimation1.22.65.61.6-2.0-2.0-2.0-1.6-2.4-0.8-0.00.8
Bone: endosteal perimeter2.75.611.82.3-2.8-2.8-2.8-2.5-3.4-1.40.11.1
Epididymis fat weight3.07.09.83.1-2.9-3.0-2.8-3.1-2.3-2.82.0-1.0
Delta time in closed arm before/after self-admin0.70.61.1-1.01.10.90.90.90.80.6-0.2-0.3
Delta time in open arm before/after self-admin0.20.20.40.5-0.5-0.4-0.6-0.6-0.5-0.40.10.1
Diff in mean of infusions in LGA sessions0.30.30.6-0.70.80.70.80.60.60.4-0.2-0.0
Delay discount exponential model param0.20.30.80.1-0.00.1-0.1-0.10.9-0.50.8-0.8
Extinction: sum of active levers before priming3.63.54.7-2.22.02.01.81.91.02.2-2.01.5
Active lever presses in extinction session 61.01.02.6-1.01.21.11.01.01.60.50.2-0.6
Bone: final force1.52.33.0-1.71.71.71.71.60.71.7-1.51.1
Bone: final moment1.22.02.6-1.61.61.61.51.50.71.6-1.41.0
Food consumed during 24 hour testing period0.40.50.80.7-0.5-0.7-0.8-0.8-0.1-0.90.9-0.7
Glucose1.62.45.91.6-1.7-1.8-1.4-1.8-2.4-0.9-0.10.9
Heart weight1.21.72.51.5-1.5-1.5-1.4-1.6-1.4-1.30.7-0.3
Delay discount hyperbolic model param0.20.30.80.1-0.10.0-0.1-0.10.9-0.50.8-0.8
Intermittent access intake day 1-15 change1.91.92.61.5-1.4-1.5-1.4-1.5-0.6-1.61.4-1.1
Intermittent access intake escalation1.71.62.21.5-1.2-1.5-1.4-1.5-0.9-1.41.1-0.8
Intermittent access intake escalation 20.80.81.11.0-0.8-1.0-0.9-1.0-0.2-1.11.0-0.8
Intermitt. access day 1 inactive lever presses1.31.42.61.4-1.6-1.3-1.4-1.3-0.9-1.10.8-0.4
Intermitt. access day 15 inactive lever presses1.71.82.61.6-1.6-1.5-1.4-1.5-1.6-1.30.7-0.1
Intermitt. access escalation Index2.72.43.21.8-1.6-1.7-1.6-1.7-0.9-1.81.5-1.1
Intermittent access day 1 total infusions2.83.29.81.7-2.0-1.8-1.7-1.8-3.1-0.9-0.31.3
Intermittent access day 15 total infusions6.37.19.73.1-3.1-3.0-2.9-3.0-3.0-2.51.4-0.4
Intermittent access terminal intake (last 3 days)4.24.68.12.5-2.5-2.4-2.2-2.4-2.8-1.80.80.1
Intermittent access total infusions2.62.96.41.9-2.0-1.9-1.7-1.9-2.5-1.30.30.5
Intermittent access day 1 locomotion1.21.24.20.8-1.2-0.9-0.9-0.9-2.1-0.1-0.71.2
Intermittent access day 15 total locomotion4.04.35.82.4-2.3-2.3-2.4-2.3-2.3-2.01.1-0.4
Intermittent access total locomotion4.65.310.62.6-2.6-2.6-2.6-2.6-3.3-1.70.50.5
Intermittent access standard deviation0.80.81.11.0-0.9-1.0-0.8-1.0-0.9-1.00.8-0.6
Left kidney weight1.02.84.11.9-1.5-1.7-1.7-1.9-0.6-2.01.9-1.6
Right kidney weight1.02.74.71.7-1.3-1.4-1.4-1.60.1-2.12.2-2.0
Cocaine induced anxiety0.00.00.10.20.1-0.0-0.2-0.2-0.4-0.20.1-0.1
Post-drug Anxiety0.80.91.5-1.11.21.21.11.11.10.7-0.2-0.2
Baseline Anxiety1.71.83.3-1.61.41.51.51.51.81.2-0.6-0.0
Tail length0.82.56.4-1.61.41.61.81.92.51.10.0-0.9
Length with tail2.38.513.5-3.23.23.23.53.53.72.6-1.1-0.1
Length without tail2.35.17.2-2.52.72.62.62.52.42.1-1.30.5
Times rat made contact with spout0.60.71.4-0.80.70.70.50.5-0.31.0-1.21.1
Lifetime Intake2.02.35.41.7-1.8-1.7-1.4-1.7-2.3-1.10.20.5
Liver weight, left0.10.20.30.5-0.6-0.5-0.4-0.5-0.4-0.50.4-0.2
Liver weight, right0.30.40.90.6-0.3-0.2-0.4-0.70.2-1.01.0-0.9
Locomotor activity1.01.52.51.3-1.2-1.0-1.3-1.4-0.4-1.61.4-1.1
Locomotor testing distance1.11.82.91.4-1.4-1.2-1.5-1.4-0.4-1.71.5-1.2
Locomotor testing rearing0.91.42.41.3-1.4-1.1-1.4-1.5-1.5-1.20.50.1
Locomotion in novel chamber5.56.89.23.0-3.0-3.0-3.0-2.9-2.7-2.51.6-0.7
Locomotion in novel chamber post-restriction3.03.64.72.2-2.1-2.0-2.2-2.0-1.9-2.01.5-0.9
Fecal boli incidents, locomotor time 10.10.10.20.3-0.2-0.1-0.4-0.4-0.4-0.30.2-0.2
Change in fecal boli incidents, locomotor task0.40.40.7-0.70.60.70.70.7-0.00.8-0.70.5
Time >=10cm from walls, locomotor time 11.51.56.11.0-1.1-1.2-1.1-1.0-2.5-0.2-0.61.0
Bouts of movement, locomotor time 10.70.81.6-1.01.20.80.81.31.10.7-0.0-0.5
Total resting periods, locomotor time 10.40.40.9-0.60.90.50.40.90.90.30.2-0.6
Rest time, locomotor task time 11.82.03.51.5-1.1-1.0-1.4-1.3-0.2-1.91.8-1.7
Distance moved, locomotor task time 10.40.41.5-0.3-0.00.10.30.1-0.60.8-1.11.2
Vertical activity count, locomotor time 10.80.81.51.0-1.2-1.1-0.8-1.1-1.2-0.60.10.3
Time >=10cm from walls, locomotor time 20.20.20.50.4-0.2-0.3-0.7-0.20.4-0.40.5-0.7
Bouts of movement, locomotor time 20.50.50.8-0.80.80.80.70.90.90.7-0.4-0.0
Total resting periods, locomotor time 20.20.20.3-0.50.60.50.40.60.40.5-0.40.1
Rest time, locomotor task time 21.82.15.41.6-1.5-1.5-1.5-1.7-2.3-1.10.40.2
Distance moved, locomotor task time 20.70.82.8-0.90.80.80.90.91.70.6-0.0-0.4
Vertical activity count, locomotor time 20.80.94.0-0.20.20.30.20.42.0-0.41.1-1.5
Light reinforcement 10.71.42.01.3-1.2-1.4-1.1-1.3-0.3-1.41.3-0.9
Light reinforcement 22.73.64.72.1-2.0-2.2-2.0-2.1-1.0-2.21.9-1.2
Bone: marrow area1.22.65.61.6-2.0-2.0-2.0-1.6-2.4-0.8-0.00.8
Bone: maximum diameter0.20.30.50.6-0.5-0.5-0.7-0.6-0.2-0.70.6-0.5
Bone: maximum force1.83.16.3-1.71.51.51.41.4-0.42.2-2.52.4
Bone: maximum moment1.62.75.2-1.61.41.51.31.3-0.42.0-2.32.2
Mean time between licks in bursts0.91.31.8-1.31.31.21.31.41.11.2-0.80.3
Mean num. licks in bursts0.10.10.1-0.20.10.30.20.1-0.20.2-0.30.4
Cd content in liver1.71.82.51.5-1.4-1.4-1.5-1.4-0.6-1.61.3-1.0
Co content in liver0.60.81.80.7-0.4-0.4-0.5-0.80.6-1.21.3-1.3
Cu content in liver0.20.20.5-0.50.40.40.70.60.70.3-0.1-0.1
Fe content in liver0.00.00.1-0.20.20.30.2-0.10.00.1-0.10.2
K content in liver1.51.53.1-1.21.11.11.20.8-0.31.4-1.81.7
Mg content in liver1.01.03.7-0.1-0.1-0.2-0.0-0.4-1.70.6-1.51.9
Mn content in liver1.21.31.9-1.31.31.31.41.10.71.2-1.10.7
Na content in liver0.10.10.4-0.10.20.10.40.10.6-0.10.4-0.6
Rb content in liver1.51.95.61.2-1.3-1.3-1.4-1.5-2.4-0.6-0.51.2
Se content in liver0.30.31.00.3-0.5-0.6-0.2-0.3-1.00.2-0.60.8
Sr content in liver2.11.93.0-1.51.61.61.61.61.71.1-0.3-0.4
Zn content in liver0.70.81.2-1.01.01.11.01.00.90.8-0.60.2
Bone: minimum diameter1.12.16.31.1-1.4-1.4-1.6-1.4-2.5-0.4-0.61.4
Time in familiar zone, hab. session 10.40.40.90.7-0.7-0.7-0.7-0.8-0.9-0.40.00.3
Time in novel zone, hab. session 10.10.10.2-0.30.20.20.20.40.40.20.0-0.2
Total zone transitions, hab. session 10.30.40.6-0.70.80.70.60.40.10.6-0.70.7
Total locomotion distance, hab. session 10.60.81.41.0-0.9-1.0-1.1-1.2-1.0-0.90.40.0
Locomotion velocity, hab. session 10.20.30.70.6-0.5-0.5-0.7-0.8-0.6-0.70.30.0
Time in familiar zone, hab. session 20.60.61.6-0.70.90.90.80.81.30.40.1-0.5
Time in novel zone, hab. session 20.40.41.30.1-0.3-0.4-0.3-0.2-1.10.3-0.81.1
Total zone transitions, hab. session 22.22.87.6-1.41.01.00.81.0-1.12.0-2.72.8
Total locomotion distance, hab. session 20.50.62.1-0.0-0.2-0.3-0.4-0.3-1.30.4-1.11.5
Locomotion velocity, hab. session 20.50.72.30.4-0.5-0.6-0.7-0.7-1.50.1-0.81.3
Novel to familiar place preference ratio0.30.30.8-0.50.30.20.50.5-0.30.7-0.90.9
Novelty place preference0.20.20.7-0.2-0.0-0.10.30.2-0.50.5-0.70.8
Time in novel zone, NPP test0.20.20.7-0.20.0-0.00.30.2-0.50.5-0.80.8
Total zone transitions, NPP test1.01.42.9-1.21.11.00.71.0-0.21.5-1.71.6
Total locomotion distance, NPP test0.20.20.70.2-0.2-0.3-0.6-0.4-0.80.0-0.50.7
Locomotion velocity, NPP test0.10.20.50.2-0.3-0.3-0.6-0.4-0.7-0.1-0.30.5
Intraocular pressure0.81.12.41.0-0.7-0.7-0.8-0.90.4-1.41.5-1.5
Delta distance traveled before/after self-admin0.00.00.10.10.0-0.0-0.3-0.10.0-0.20.1-0.1
Delta ambulatory time before/after self-admin0.00.00.2-0.20.30.30.00.20.40.00.1-0.1
Parametrial fat weight1.73.35.62.0-2.0-2.2-2.0-2.2-2.4-1.50.50.3
Pavlov. Cond. lever latency0.10.20.30.4-0.5-0.3-0.4-0.4-0.0-0.50.5-0.5
Pavlov. Cond. magazine entry latency0.40.51.60.1-0.3-0.3-0.3-0.1-1.20.4-0.91.3
Pavlov. Cond. change in total contacts0.50.51.30.7-0.8-0.8-0.7-0.8-1.1-0.4-0.10.5
Pavlov. Cond. index score0.10.10.20.4-0.3-0.3-0.3-0.4-0.4-0.30.10.1
Pavlov. Cond. latency score0.10.10.20.2-0.2-0.3-0.2-0.3-0.5-0.1-0.20.3
Pavlov. Cond. lever contacts0.00.00.1-0.00.1-0.00.1-0.1-0.20.1-0.20.3
Pavlov. Cond. magazine entry number0.10.10.1-0.40.30.30.40.30.20.4-0.30.2
Pavlov. Cond. intertrial magazine entries0.40.41.20.5-0.4-0.5-0.1-0.40.4-0.81.0-1.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.2-0.1-0.1-0.2-0.3-0.3-0.2-0.00.2
Pavlov. Cond. response bias0.00.10.10.3-0.2-0.2-0.3-0.3-0.3-0.20.10.1
Pavlov. Cond. lever latency0.00.00.1-0.0-0.2-0.20.20.30.30.10.2-0.3
Pavlov. Cond. magazine entry latency2.93.35.3-2.01.81.91.51.60.12.2-2.32.0
Pavlov. Cond. change in total contacts0.40.51.5-0.50.40.30.20.3-0.70.8-1.11.2
Pavlov. Cond. index score0.70.91.7-1.00.91.00.60.6-0.21.1-1.31.2
Pavlov. Cond. latency score0.50.61.3-0.80.80.80.40.5-0.20.9-1.11.1
Pavlov. Cond. lever contacts0.00.00.10.10.20.2-0.2-0.30.0-0.30.2-0.2
Pavlov. Cond. magazine entry number3.64.46.82.3-2.1-2.2-1.8-1.9-0.2-2.52.6-2.3
Pavlov. Cond. intertrial magazine entries1.01.42.21.3-1.4-1.5-1.1-0.9-0.4-1.21.2-1.0
Pavlov. Cond. lever-magazine prob. diff.1.01.32.2-1.21.21.20.90.9-0.11.3-1.51.3
Pavlov. Cond. response bias0.40.60.9-0.80.90.90.50.4-0.10.8-1.00.9
Time in closed arm before self-admin0.10.20.40.4-0.6-0.5-0.4-0.4-0.4-0.2-0.00.3
Time in closed arm after self-admin0.00.00.1-0.20.20.20.20.20.20.00.2-0.3
Time in open arm before self-admin0.30.30.4-0.60.60.60.70.60.60.4-0.2-0.1
Time in open arm after self-admin0.00.00.1-0.00.20.10.10.00.3-0.10.2-0.2
Bone: periosteal estimation0.10.30.50.5-0.7-0.6-0.7-0.5-0.7-0.40.10.1
Bone: periosteal perimeter0.20.31.00.4-0.6-0.5-0.7-0.5-1.0-0.1-0.30.6
Bone: post-yield work2.63.611.30.3-0.8-0.7-0.8-0.8-3.30.9-2.53.4
Progressive ratio test 1 active lever presses1.41.42.01.4-1.4-1.3-1.2-1.3-0.9-1.41.1-0.7
Progressive ratio test 1 breakpoint1.31.32.01.3-1.4-1.2-1.1-1.2-0.7-1.31.1-0.8
Progressive ratio test 1 inactive lever presses0.40.40.80.7-0.9-0.7-0.6-0.7-0.6-0.60.4-0.2
Progressive ratio test 2 active lever presses2.62.83.92.0-2.0-1.9-1.8-1.9-1.6-1.81.3-0.7
Progressive ratio test 2 breakpoint3.53.95.22.3-2.2-2.1-2.0-2.1-1.4-2.31.8-1.2
Progressive ratio test 2 inactive lever presses6.47.410.33.2-3.2-3.1-3.0-3.1-2.7-2.71.7-0.6
Incentive Sensitization - Responses0.30.30.60.6-0.6-0.5-0.6-0.5-0.7-0.50.3-0.0
Incentive Sensitization - Breakpoint0.50.50.70.8-0.8-0.8-0.8-0.8-0.9-0.70.4-0.2
Sum of active levers in priming session hrs 5-61.01.03.4-0.10.40.40.20.31.8-0.61.3-1.7
Progressive ratio3.13.67.8-1.81.11.41.31.5-0.62.5-2.82.7
Food seeking constrained by brief footshock0.50.60.9-0.80.40.70.91.00.80.9-0.60.4
Seeking ratio, punishment vs. effort1.82.24.91.4-1.0-1.0-0.9-1.10.8-1.92.2-2.2
Retroperitoneal fat weight4.715.421.14.6-4.5-4.5-4.1-4.5-3.4-4.22.9-1.5
Reaction time number correct0.30.41.2-0.50.80.70.50.51.10.20.3-0.6
Reaction time mean minus median1.41.93.5-1.51.71.91.51.00.41.2-1.51.2
Reaction time mean minus median AUC1.11.43.0-1.31.71.71.40.80.90.8-0.80.4
Reaction time num false alarms0.30.41.2-0.20.40.30.30.21.1-0.30.7-1.0
Reaction time num false alarms AUC0.60.82.1-0.91.01.11.00.91.50.50.1-0.5
Reaction time trials correct on left0.30.41.2-0.50.80.70.50.51.10.20.3-0.6
Reaction time trials on left0.40.51.6-0.71.00.80.60.61.30.20.2-0.6
Reaction time mean0.10.10.40.00.00.00.0-0.2-0.70.1-0.50.6
Reaction time mean AUC0.10.20.60.1-0.1-0.1-0.1-0.3-0.80.1-0.50.6
Median of all reaction times0.20.20.90.3-0.4-0.4-0.3-0.4-1.00.0-0.40.6
Reaction time omissions1.41.93.5-1.61.91.81.51.31.21.2-1.00.5
Reaction time false alarm rate0.20.20.7-0.40.40.40.50.50.80.10.2-0.5
Reaction time premature initiation rate2.43.24.6-2.12.02.01.82.11.61.9-1.30.7
Reaction time premature initiations3.24.56.5-2.52.62.52.22.42.52.0-1.10.3
Std. dev. reaction times0.40.51.0-0.70.91.00.70.4-0.00.6-0.90.7
Reaction time trials completed0.40.51.6-0.71.00.80.60.61.30.20.2-0.6
Reaction time trials AUC0.30.41.1-0.60.80.70.50.51.10.20.2-0.5
Run reversals in cocaine runway, females1.71.73.3-1.21.11.11.01.1-0.31.6-1.81.7
Run reversals in cocaine runway, males0.30.30.9-0.20.50.50.30.00.9-0.40.6-0.9
Latency to leave start box in cocaine runway0.30.41.20.1-0.1-0.3-0.3-0.1-1.00.4-0.81.1
Latency to leave start box in cocaine runway, F0.20.21.0-0.10.2-0.0-0.20.0-0.60.5-0.81.0
Latency to leave start box in cocaine runway, M0.00.00.00.1-0.2-0.2-0.10.0-0.20.1-0.10.1
Std. dev. time between licks in bursts0.60.72.4-0.61.00.80.40.81.60.10.5-1.0
Total sessions with >9 infusions0.60.61.10.9-1.0-0.9-0.8-0.9-1.1-0.70.30.1
Short access day 1 total inactive lever presses2.02.34.21.8-2.0-1.7-1.7-1.7-1.1-1.51.0-0.4
Short access day 10 total inactive lever presses1.01.21.81.3-1.3-1.3-1.3-1.3-0.7-1.10.7-0.2
Short access day 1 total infusions1.41.52.91.4-1.7-1.4-1.2-1.4-1.7-0.90.20.4
Short access day 10 total infusions1.21.35.60.5-0.8-0.6-0.6-0.6-2.40.2-1.11.7
Short access total infusions0.60.72.70.6-0.9-0.8-0.5-0.6-1.6-0.1-0.50.9
Short access day 1 locomotion1.21.33.41.2-1.3-1.2-1.2-1.2-1.8-0.70.00.5
Short access day 10 total locomotion0.50.61.90.7-0.9-0.7-0.8-0.7-1.4-0.1-0.30.6
Short access total locomotion0.40.41.20.5-0.9-0.7-0.5-0.5-1.1-0.0-0.40.6
One hour access (0.3 mA shock)6.47.510.43.2-3.2-3.1-2.9-3.1-2.5-2.81.9-1.0
Compulsive drug intake3.53.55.5-2.22.02.22.22.22.31.7-0.8-0.1
One hour access (shock baseline)8.19.313.13.6-3.5-3.5-3.3-3.5-2.6-3.22.2-1.2
Social response proportion0.80.81.4-0.91.01.10.60.6-0.11.0-1.21.1
Social responses0.30.40.9-0.61.00.90.60.40.80.3-0.1-0.2
Social time0.50.61.2-0.91.11.10.70.70.60.7-0.60.4
Soleus weight3.811.214.03.7-3.7-3.7-3.6-3.3-1.5-3.73.5-2.8
Bone: stiffness1.52.35.4-1.41.11.11.01.0-0.71.9-2.32.3
Tibialis anterior weight6.823.436.8-5.35.85.75.75.56.13.9-1.6-0.6
Time to tail flick, vehicle, before self-admin1.21.23.4-0.80.20.50.70.6-1.11.3-1.71.8
Time to tail flick, vehicle, after self-admin2.42.63.4-1.81.71.71.81.70.91.9-1.61.2
Time to tail flick, test, before self-admin0.60.62.00.0-0.2-0.2-0.1-0.1-1.30.6-1.11.4
Time to tail flick, test, after self-admin0.10.10.3-0.30.30.20.60.30.30.3-0.20.0
Delta time to tail flick, vehicle, before/after SA0.90.91.4-1.01.21.01.11.01.00.9-0.50.1
Delta time to tail flick, test, before/after SA1.41.24.3-0.80.80.81.11.02.10.10.9-1.5
Tibia length0.20.72.3-0.30.60.60.50.41.5-0.31.0-1.3
Ambulatory time before self-admin0.10.10.4-0.10.10.10.00.0-0.50.4-0.50.6
Ambulatory time after self-admin0.50.61.90.7-0.6-0.7-0.8-0.8-1.4-0.2-0.40.9
Bone: tissue strength0.30.30.80.6-0.4-0.4-0.5-0.9-0.9-0.50.00.3
Total heroin consumption3.84.46.4-2.42.42.42.52.41.72.2-1.50.8
Bone: trabecular number1.11.65.5-0.80.50.60.40.3-1.41.3-2.12.3
Bone: trabecular spacing0.40.51.50.4-0.4-0.5-0.1-0.00.8-0.61.1-1.2
Bone: trabecular thickness0.80.93.30.6-0.8-0.7-0.9-0.9-1.8-0.1-0.71.3
Bone: trabecular tissue density5.27.39.63.0-2.9-3.0-2.8-2.6-1.0-3.12.9-2.3
Water consumed over 24 hours0.80.91.6-1.10.90.80.81.00.21.3-1.20.9
Number of responses in last shaping day0.50.50.70.8-0.7-0.8-0.6-0.8-0.1-0.80.7-0.6