Hub : Genes

Ehbp1l1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_039079580.1 0.06 0.04 2.9e-04 0.02 0.02 0.02 0.02 1.9e-03 1.8e-03 5.9e-03 1.5e-03
2 pVTA gene expression Ehbp1l1 0.07 0.05 4.1e-03 -0.01 0.01 -0 -0 8.4e-01 1.1e-01 3.9e-01 6.8e-01
3 Brain mRNA stability Ehbp1l1 0.04 0.02 3.6e-03 0.03 0.02 0.02 0.02 7.6e-04 9.7e-03 6.4e-03 3.8e-03
4 PL intron excision ratio chr1_202997203_202997369 0.03 0.02 3.0e-03 0.01 0.02 0.01 0.01 2.1e-02 5.7e-03 2.6e-02 9.5e-03
5 Adipose gene expression Ehbp1l1 0.31 0.11 0.0e+00 0.16 0.21 0.2 0.2 3.4e-17 1.7e-22 5.0e-22 7.1e-22
6 NAcc gene expression Ehbp1l1 0.13 0.06 1.1e-15 0.15 0.14 0.12 0.13 1.1e-16 1.8e-15 5.7e-14 2.9e-15
7 Brain isoform ratio NM_001129997.1 0.04 0.03 7.8e-03 0.02 0.02 0.01 0.03 3.1e-03 9.7e-03 1.8e-02 7.5e-04
8 OFC gene expression Ehbp1l1 0.48 0.17 6.5e-05 0.11 0.18 0.22 0.19 1.4e-03 3.6e-05 5.7e-06 2.6e-05
9 Adipose intron excision ratio chr1_203004677_203007128 0.1 0.07 1.1e-04 0.02 0.02 0.05 0.02 1.7e-03 1.6e-03 6.1e-06 2.9e-03
10 BLA gene expression Ehbp1l1 0.11 0.06 1.9e-04 0.06 0.06 0.05 0.05 5.2e-04 4.4e-04 1.0e-03 7.9e-04
11 Adipose isoform ratio XM_039079598.1 0.04 0.03 2.0e-03 0.03 0.02 0.03 0.02 5.1e-04 5.8e-03 7.1e-04 9.2e-04
12 PL gene expression Ehbp1l1 0.15 0.07 1.9e-13 0.1 0.13 0.13 0.13 1.3e-11 1.5e-14 2.9e-14 1.7e-14
13 Brain gene expression Ehbp1l1 0.19 0.09 1.6e-09 0.06 0.12 0.08 0.11 3.7e-06 5.0e-11 3.1e-08 1.0e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density1.01.74.11.00.1-0.6-0.4-1.9-0.8-1.30.1-1.62.01.91.61.6
Area under the delay curve0.80.82.4-0.10.5-0.0-0.8-0.6-1.3-1.3-1.0-0.20.60.81.51.6
BMI with tail3.912.731.03.8-1.2-2.90.1-5.6-1.2-0.92.8-5.14.95.23.33.4
BMI without tail1.83.79.22.0-0.7-1.7-0.0-3.0-0.9-0.71.3-2.42.42.92.12.2
Body weight2.410.220.94.6-3.4-4.02.7-4.31.72.04.2-4.32.53.00.30.5
Weight adjusted by age1.51.73.11.7-1.6-1.51.7-1.01.61.81.6-0.70.30.3-1.0-1.0
Bone surface2.23.99.12.6-1.8-2.01.8-3.01.20.42.1-2.82.61.90.20.3
Bone volume1.11.96.21.4-0.6-0.90.7-2.30.2-0.40.8-2.12.51.70.70.7
Breakpoint value in progressive ratio session1.82.03.92.0-1.8-1.81.8-1.51.51.61.2-1.30.70.7-0.7-0.6
Number of licking bursts0.10.20.40.6-0.5-0.60.5-0.50.40.40.2-0.30.40.0-0.1-0.1
Context. condit. distance diff. score1.11.32.9-1.41.61.2-1.70.9-1.4-1.3-1.30.4-0.20.00.90.8
Locomotion velocity, session 10.20.20.70.3-0.4-0.40.20.20.30.40.9-0.1-0.7-0.3-0.3-0.3
Locomotion distance, session 10.91.22.81.2-0.4-1.1-0.2-1.6-0.6-0.60.7-1.01.11.71.31.5
Locomotion velocity, session 21.92.24.92.2-1.5-2.01.1-2.10.50.91.7-1.71.21.70.40.5
Locomotion distance, session 20.81.12.51.4-0.7-1.30.1-1.6-0.4-0.10.7-0.80.91.61.21.3
Locomotion velocity, session 30.81.01.90.30.7-0.2-1.1-0.8-1.3-0.70.8-1.41.11.21.21.1
Locomotion distance, session 30.00.00.10.00.2-0.1-0.30.0-0.3-0.10.2-0.30.00.10.20.1
Stereotopy head waving bouts, day 31.01.22.4-0.41.10.5-1.5-0.4-1.4-1.60.9-1.10.80.91.41.3
Stereotopy head waving duration, day 30.70.82.3-0.91.11.1-1.30.1-1.2-1.5-0.0-0.10.50.40.90.9
Locomotion velocity, session 71.92.04.3-0.21.30.4-1.6-1.1-1.9-1.2-0.6-1.21.71.82.11.8
Locomotion distance, session 70.60.82.00.40.5-0.4-1.0-0.8-1.1-0.60.1-0.80.61.21.41.3
Stereotopy head waving bouts, day 70.40.41.0-0.60.70.8-0.5-0.3-0.6-0.9-0.7-0.31.00.40.50.5
Stereotopy head waving duration, day 70.50.62.10.8-0.6-0.60.6-1.40.1-0.3-0.1-0.61.41.20.50.7
Locomotion velocity, session 81.01.13.01.5-1.3-1.71.1-0.31.10.91.7-0.7-0.6-0.1-0.7-0.5
Locomotion distance, session 80.50.81.7-0.10.80.3-1.1-0.6-1.2-0.70.4-1.31.01.01.10.9
Degree of sensitization distance0.70.71.60.30.4-0.2-0.7-0.9-0.8-0.70.5-1.30.91.11.11.0
Degree of sensitization stereotypy0.20.31.30.5-0.3-0.30.5-0.90.20.1-0.3-0.61.10.60.10.1
Conditioned locomotion1.21.52.51.6-1.5-1.51.3-0.91.21.51.6-1.40.10.4-0.7-0.6
Cocaine response after cond. corrected0.60.72.0-0.91.20.8-1.40.9-1.2-0.9-0.00.3-0.6-0.10.60.6
Cocaine response after cond. not corrected0.50.61.6-0.81.00.7-1.30.7-1.0-1.00.30.3-0.4-0.10.60.5
Cocaine response before conditioning0.30.30.80.7-0.8-0.50.9-0.60.80.50.4-0.00.50.1-0.4-0.4
Saline control response2.12.86.72.6-2.4-2.52.0-1.71.71.02.0-1.10.31.1-0.5-0.1
Bone: connectivity density1.52.46.32.0-1.1-1.60.7-2.50.2-0.60.8-2.02.12.11.11.3
Bone: cortical apparent density0.20.31.30.3-0.7-0.50.6-0.10.50.5-0.91.1-0.50.1-0.00.1
Bone: cortical area0.71.02.31.1-0.9-0.91.1-0.70.81.51.5-1.30.50.0-0.8-1.0
Bone: cortical porosity0.40.41.40.40.0-0.3-0.2-0.8-0.3-0.7-0.4-0.40.81.20.80.9
Bone: cortical porosity0.40.51.40.9-0.6-0.80.3-1.00.2-0.20.2-0.60.71.20.50.7
Bone: cortical thickness2.33.79.42.4-2.6-2.62.5-0.72.13.11.8-0.5-0.9-0.3-1.6-1.5
Bone: cortical thickness0.91.12.41.1-1.3-1.51.10.21.01.50.90.5-1.4-0.4-0.9-0.7
Bone: cortical tissue density0.30.41.30.3-0.9-0.60.8-0.10.60.6-0.91.2-0.50.1-0.10.0
Condit. Reinf. active minus inactive responses0.20.20.60.5-0.3-0.50.0-0.6-0.10.0-0.2-0.10.40.80.50.6
Condit. Reinf. active-inactive response ratio0.10.10.8-0.0-0.2-0.10.1-0.0-0.10.0-0.90.8-0.20.10.20.3
Condit. Reinf. active responses0.20.31.00.40.1-0.2-0.3-0.8-0.40.10.1-0.70.91.00.60.5
Condit. Reinf. inactive responses0.50.62.20.10.60.3-0.7-0.8-0.7-0.10.7-1.51.31.00.70.4
Incentive salience index mean0.50.62.00.8-0.2-0.7-0.1-1.3-0.40.00.3-0.91.01.40.90.9
Condit. Reinf. lever presses0.50.72.50.8-0.3-0.40.2-1.20.00.61.3-1.61.11.00.20.0
Condit. Reinf. active minus inactive responses0.20.30.9-0.70.61.0-0.4-0.0-0.3-0.5-0.6-0.30.7-0.10.20.1
Condit. Reinf. active-inactive response ratio0.70.82.4-1.11.31.6-0.8-0.0-0.7-0.4-0.1-1.21.3-0.10.2-0.2
Condit. Reinf. active responses0.20.31.0-0.10.10.2-0.1-0.5-0.3-0.8-1.00.20.80.60.70.8
Condit. Reinf. inactive responses0.60.72.00.7-0.5-0.90.1-0.7-0.2-1.1-1.01.10.11.11.01.4
Condit. Reinf. lever presses1.11.52.51.6-1.4-1.21.6-1.51.20.91.0-1.61.20.5-0.5-0.6
Condit. Reinf. lever reinforcers received0.20.20.70.2-0.3-0.10.3-0.60.1-0.5-0.80.10.70.60.40.5
Conditioned reinforcement - actives0.30.31.1-0.50.40.60.10.70.20.10.10.6-0.1-0.8-0.9-1.1
Conditioned reinforcement - inactives3.94.410.4-3.22.73.2-1.92.5-1.4-1.4-2.82.1-0.6-1.7-0.1-0.5
Conditioned locomotion4.85.812.2-3.52.93.3-2.23.2-1.5-1.4-2.53.2-1.4-2.4-0.5-0.9
Patch foraging indifference point 0 sec0.10.10.3-0.20.30.2-0.30.1-0.3-0.4-0.60.40.10.30.30.3
Patch foraging indifference point AUC1.82.14.81.9-2.0-1.72.2-1.31.91.61.0-0.80.40.4-1.0-0.9
Delay disc. indifference point, 0s delay1.21.33.3-0.40.90.1-1.3-0.4-1.8-1.7-0.8-0.10.50.71.71.8
Delay disc. indifference point, 16s delay1.21.33.7-1.21.31.2-1.20.1-1.4-1.2-1.90.40.60.21.21.1
Delay disc. indifference point, 2s delay0.20.20.4-0.10.50.2-0.5-0.2-0.7-0.60.1-0.60.50.10.50.4
Delay disc. indifference point, 24s delay0.10.10.6-0.1-0.0-0.2-0.20.4-0.3-0.2-0.40.5-0.8-0.30.20.4
Delay disc. indifference point, 4s delay0.60.72.1-0.00.4-0.2-0.9-0.2-1.2-1.2-0.50.30.10.61.31.4
Delay disc. indifference point, 8s delay0.40.41.6-0.10.2-0.1-0.6-0.2-0.9-1.0-0.60.00.00.51.11.3
Indifference point function ln k3.85.312.1-3.03.22.6-3.52.4-3.0-2.2-1.71.5-1.2-0.91.41.1
Indifference point function log k3.85.312.1-3.03.22.6-3.52.4-3.0-2.2-1.71.5-1.2-0.91.41.1
Patch foraging total patch changes 0 sec0.00.00.3-0.10.0-0.0-0.10.30.10.0-0.20.5-0.40.0-0.1-0.1
Patch foraging total patch changes 12 sec2.22.86.52.5-2.3-2.32.1-2.11.71.41.0-1.00.91.5-0.3-0.1
Patch foraging total patch changes 18 sec0.20.31.00.7-0.5-0.50.6-1.00.30.10.2-0.50.90.80.10.2
Patch foraging total patch changes 24 sec1.51.94.01.7-2.0-1.62.0-0.71.91.51.3-0.3-0.30.1-1.2-1.0
Patch foraging total patch changes 6 sec0.50.82.21.5-1.1-1.40.7-1.10.60.30.6-0.70.41.00.20.3
Patch foraging time to switch 0 sec1.82.77.91.6-0.7-1.10.5-2.8-0.3-0.20.7-2.32.72.51.41.3
Patch foraging water rate 0 sec2.64.111.6-2.71.72.3-1.23.4-0.2-0.2-1.22.0-2.5-3.0-1.3-1.5
Patch foraging water rate 12 sec4.56.919.4-3.42.52.7-2.34.4-1.2-1.3-1.63.1-3.5-3.4-0.8-0.9
Patch foraging water rate 18 sec1.41.84.5-1.91.71.6-1.72.1-1.1-0.9-0.41.0-1.6-1.30.1-0.0
Patch foraging water rate 24 sec2.23.07.9-2.61.82.3-1.52.8-0.8-0.6-0.41.4-2.0-2.2-0.7-0.9
Patch foraging water rate 6 sec1.92.88.8-2.11.61.6-1.53.0-0.6-0.4-0.41.5-2.5-2.4-0.7-0.8
Seeking ratio, delayed vs. immediate footshock0.50.61.7-0.10.4-0.0-0.7-0.5-0.8-0.8-1.10.20.60.91.21.3
Distance traveled before self-admin0.30.30.70.5-0.6-0.30.8-0.70.50.50.4-0.60.70.3-0.3-0.4
Distance traveled after self-admin0.10.10.40.0-0.40.20.6-0.20.60.5-0.2-0.00.20.0-0.4-0.4
Extensor digitorum longus weight4.317.036.26.0-5.1-5.54.5-5.03.23.85.0-4.32.23.0-0.7-0.4
Bone: elastic displacement1.01.24.6-0.80.30.3-0.41.90.10.4-0.01.2-2.1-1.7-0.9-0.9
Bone: elastic work1.01.22.71.4-1.4-1.71.00.01.11.51.5-0.2-1.2-0.4-0.8-0.7
Bone: endosteal estimation1.22.64.4-1.02.01.5-2.0-0.7-2.1-2.10.6-1.82.11.11.61.4
Bone: endosteal perimeter1.32.85.4-1.42.32.0-2.0-0.4-2.0-2.30.0-1.62.30.81.41.1
Epididymis fat weight1.53.48.0-2.52.82.6-2.61.2-2.4-2.4-1.40.20.6-0.41.10.8
Delta time in closed arm before/after self-admin0.20.21.00.6-0.4-0.8-0.2-0.00.00.11.0-0.1-0.80.10.20.4
Delta time in open arm before/after self-admin0.30.20.7-0.3-0.20.40.70.20.50.4-0.60.30.2-0.5-0.7-0.8
Diff in mean of infusions in LGA sessions0.40.51.10.4-0.8-0.41.00.11.11.00.50.2-0.4-0.4-0.9-0.8
Delay discount exponential model param0.60.61.90.1-0.30.10.70.51.11.10.90.1-0.5-0.7-1.3-1.4
Extinction: sum of active levers before priming2.52.55.72.3-1.8-2.11.5-2.41.01.20.9-1.41.51.80.30.4
Active lever presses in extinction session 62.72.64.61.4-1.7-1.22.2-0.52.12.22.1-0.9-0.1-0.6-1.9-1.9
Bone: final force1.82.95.42.2-1.9-1.91.8-2.11.41.52.3-2.31.31.1-0.5-0.4
Bone: final moment1.62.65.02.1-1.8-1.81.7-2.01.31.42.2-2.21.21.1-0.4-0.4
Food consumed during 24 hour testing period0.50.61.5-0.2-0.40.20.80.70.90.7-0.20.5-0.6-1.2-1.2-1.2
Glucose1.92.96.5-1.62.31.8-2.30.1-2.2-2.6-1.0-0.41.20.71.81.7
Heart weight2.02.96.0-2.12.31.9-2.41.3-2.1-2.1-1.71.1-0.3-0.31.31.1
Delay discount hyperbolic model param0.50.51.6-0.0-0.30.20.60.51.01.00.70.2-0.4-0.6-1.2-1.3
Intermittent access intake day 1-15 change1.11.12.2-1.20.61.20.11.40.40.7-0.51.3-0.8-1.5-1.3-1.5
Intermittent access intake escalation0.70.71.3-1.10.71.1-0.21.10.10.4-0.70.9-0.4-1.0-0.8-1.0
Intermittent access intake escalation 20.80.81.9-0.90.10.90.51.10.70.9-0.40.9-0.7-1.2-1.3-1.4
Intermitt. access day 1 inactive lever presses1.71.83.7-1.91.71.9-1.51.2-1.3-1.0-1.91.6-0.1-0.60.50.3
Intermitt. access day 15 inactive lever presses1.61.74.4-2.01.82.1-1.31.4-1.0-0.6-1.71.30.0-1.1-0.1-0.4
Intermitt. access escalation Index3.12.75.8-1.42.01.2-2.30.5-2.4-2.3-1.90.10.20.41.91.8
Intermittent access day 1 total infusions5.26.013.8-2.23.42.4-3.30.3-3.5-3.7-2.00.11.80.72.52.1
Intermittent access day 15 total infusions4.75.212.4-3.13.53.3-2.91.9-2.6-2.6-2.31.50.5-1.00.80.4
Intermittent access terminal intake (last 3 days)3.43.79.6-2.63.12.9-2.51.2-2.4-2.3-1.60.41.0-0.60.80.4
Intermittent access total infusions3.64.09.2-2.13.02.4-2.70.6-2.8-2.8-1.80.21.40.21.61.2
Intermittent access day 1 locomotion4.44.610.7-1.42.81.6-3.0-0.1-3.2-3.3-1.40.51.51.12.62.3
Intermittent access day 15 total locomotion3.33.67.6-2.52.82.6-2.31.3-2.2-2.1-2.21.90.5-0.60.90.5
Intermittent access total locomotion5.36.112.9-2.63.62.9-3.30.5-3.4-3.4-2.30.71.80.52.11.7
Intermittent access standard deviation0.91.02.2-1.41.01.3-0.61.4-0.3-0.2-0.91.5-0.5-1.2-0.6-0.8
Left kidney weight0.31.03.2-1.71.41.8-1.10.8-1.0-0.1-0.90.00.2-0.60.1-0.3
Right kidney weight0.30.82.3-1.10.51.30.20.70.21.10.1-0.30.1-1.2-1.1-1.5
Cocaine induced anxiety0.10.10.5-0.0-0.00.10.30.20.30.30.6-0.30.1-0.4-0.6-0.7
Post-drug Anxiety1.51.74.21.0-1.3-0.81.7-0.31.71.62.1-0.40.1-0.6-1.6-1.7
Baseline Anxiety1.71.83.61.6-1.8-1.51.7-0.81.71.91.8-0.0-0.20.1-1.0-0.9
Tail length1.13.26.21.2-2.1-1.52.20.62.32.51.50.5-2.0-1.4-2.2-2.0
Length with tail1.76.310.92.8-3.3-2.83.3-0.93.23.33.2-1.3-0.8-0.4-2.4-2.1
Length without tail1.83.98.32.6-2.4-2.52.3-1.42.22.12.9-1.80.30.3-1.3-1.2
Times rat made contact with spout0.40.41.50.9-0.7-1.20.4-0.60.1-0.1-0.70.6-0.10.60.50.8
Lifetime Intake3.43.88.3-1.82.92.1-2.70.4-2.8-2.8-1.60.11.40.41.81.4
Liver weight, left0.00.10.3-0.10.30.2-0.30.0-0.2-0.20.5-0.50.20.00.0-0.0
Liver weight, right0.20.32.30.20.2-0.3-0.40.1-0.2-0.31.5-1.0-0.2-0.10.0-0.0
Locomotor activity1.01.65.0-1.41.01.0-1.02.2-0.4-0.2-0.11.6-2.1-1.7-0.6-0.6
Locomotor testing distance1.42.37.3-1.51.20.9-1.32.7-0.7-0.6-0.22.2-2.6-2.0-0.5-0.4
Locomotor testing rearing1.42.25.7-1.61.31.2-1.52.2-1.0-1.7-1.02.4-1.9-1.30.20.4
Locomotion in novel chamber2.42.97.5-2.72.62.7-1.91.9-1.6-1.3-1.50.70.0-1.3-0.0-0.5
Locomotion in novel chamber post-restriction1.51.84.0-1.92.01.8-1.71.4-1.3-1.2-1.60.5-0.2-0.90.30.1
Fecal boli incidents, locomotor time 10.20.30.8-0.30.10.60.5-0.20.30.50.2-0.60.9-0.3-0.6-0.9
Change in fecal boli incidents, locomotor task0.40.41.10.5-0.0-0.5-0.6-0.5-0.5-0.60.8-0.2-0.00.80.91.0
Time >=10cm from walls, locomotor time 11.81.94.8-0.91.61.5-1.4-0.8-1.6-1.6-0.3-1.62.20.91.30.9
Bouts of movement, locomotor time 10.70.82.50.5-1.5-0.61.6-0.41.31.1-0.90.7-0.30.0-0.6-0.3
Total resting periods, locomotor time 10.50.51.70.4-1.1-0.41.3-0.41.10.8-0.90.5-0.00.2-0.4-0.2
Rest time, locomotor task time 10.70.71.9-1.20.91.2-0.61.4-0.4-0.3-0.20.5-0.7-1.3-0.6-0.7
Distance moved, locomotor task time 10.50.61.40.50.1-0.5-0.4-1.0-0.7-0.6-0.1-0.61.01.21.11.1
Vertical activity count, locomotor time 10.70.71.4-1.11.21.1-1.20.9-0.9-0.8-0.90.9-0.3-0.40.40.3
Time >=10cm from walls, locomotor time 20.10.10.5-0.30.00.40.2-0.3-0.0-0.0-0.5-0.00.70.30.0-0.0
Bouts of movement, locomotor time 20.20.30.60.5-0.7-0.60.7-0.40.60.3-0.80.50.00.20.10.3
Total resting periods, locomotor time 20.20.20.90.3-0.4-0.30.4-0.40.30.0-0.90.40.20.30.40.5
Rest time, locomotor task time 21.31.53.5-1.81.81.9-1.61.0-1.6-1.3-0.80.3-0.0-0.60.60.4
Distance moved, locomotor task time 20.70.82.01.3-1.3-1.41.2-0.61.01.20.6-0.1-0.10.2-0.6-0.4
Vertical activity count, locomotor time 20.91.03.00.1-0.6-0.40.51.21.11.10.71.0-1.7-1.2-1.3-1.2
Light reinforcement 10.20.41.3-0.40.20.2-0.10.90.0-0.3-0.91.1-0.9-0.7-0.3-0.2
Light reinforcement 20.50.71.7-1.21.11.3-0.51.0-0.3-0.2-0.5-0.30.2-1.2-0.6-1.0
Bone: marrow area1.32.84.7-1.02.11.5-2.1-0.7-2.2-2.20.5-1.82.11.21.71.5
Bone: maximum diameter0.40.82.90.3-0.30.20.8-0.40.70.81.7-1.50.8-0.4-1.0-1.2
Bone: maximum force2.44.110.32.6-1.6-1.91.4-3.10.70.92.3-3.22.62.20.40.5
Bone: maximum moment2.13.69.22.4-1.5-1.91.3-2.90.60.82.2-3.02.42.10.40.5
Mean time between licks in bursts0.50.72.31.2-1.2-1.50.7-0.20.80.51.30.1-1.0-0.1-0.30.0
Mean num. licks in bursts0.30.41.1-0.40.30.2-0.50.4-0.5-0.8-1.01.0-0.50.30.50.7
Cd content in liver1.21.33.4-1.81.01.8-0.41.60.0-0.1-1.00.7-0.6-1.7-0.9-1.1
Co content in liver1.72.06.5-1.30.50.7-0.52.2-0.0-0.2-1.82.6-2.4-1.5-0.5-0.3
Cu content in liver0.30.30.80.6-0.4-0.70.3-0.8-0.10.1-0.70.40.50.90.50.6
Fe content in liver0.30.31.40.5-0.4-0.40.5-0.10.50.61.2-0.70.1-0.2-0.6-0.7
K content in liver1.91.84.51.7-0.7-1.40.3-2.1-0.2-0.11.3-1.91.71.91.01.0
Mg content in liver2.02.04.70.60.4-0.4-0.9-1.7-1.4-1.6-0.5-0.81.92.22.12.1
Mn content in liver1.41.62.91.7-1.5-1.41.7-1.31.41.21.2-1.30.80.5-0.8-0.7
Na content in liver1.21.32.61.1-1.2-1.01.4-0.61.31.61.6-1.30.2-0.1-1.2-1.3
Rb content in liver1.72.14.7-1.11.61.1-1.90.3-1.9-2.2-1.90.90.50.61.71.7
Se content in liver0.20.21.0-0.30.40.70.0-0.2-0.0-0.5-0.5-0.41.00.1-0.1-0.2
Sr content in liver2.52.35.41.3-2.1-1.42.3-0.32.12.01.1-0.1-0.7-0.6-1.8-1.6
Zn content in liver0.50.61.51.1-1.0-1.10.8-1.20.40.60.2-0.40.71.00.30.4
Bone: minimum diameter1.73.15.7-0.71.91.1-2.1-1.0-2.4-2.2-0.7-1.12.21.72.22.0
Time in familiar zone, hab. session 10.30.30.6-0.20.70.3-0.8-0.2-0.8-0.8-0.1-0.10.60.50.70.6
Time in novel zone, hab. session 10.40.41.8-0.4-0.10.20.01.00.30.1-0.00.8-1.3-0.9-0.5-0.4
Total zone transitions, hab. session 10.40.51.21.1-0.8-1.00.6-1.10.20.5-0.0-0.30.61.10.30.4
Total locomotion distance, hab. session 10.50.71.4-0.60.90.8-1.0-0.4-1.2-0.6-0.1-0.70.90.81.00.8
Locomotion velocity, hab. session 10.30.40.8-0.10.40.3-0.5-0.7-0.8-0.3-0.0-0.80.90.80.80.7
Time in familiar zone, hab. session 20.40.41.50.4-0.3-0.60.10.60.40.21.20.1-1.1-0.7-0.5-0.3
Time in novel zone, hab. session 20.40.41.4-0.00.10.1-0.1-0.7-0.4-0.5-1.20.20.90.90.80.8
Total zone transitions, hab. session 22.02.57.21.6-0.6-1.3-0.0-2.4-0.6-1.10.2-1.22.02.71.92.2
Total locomotion distance, hab. session 21.41.84.00.20.60.1-1.1-1.4-1.5-1.50.1-1.21.61.92.02.0
Locomotion velocity, hab. session 21.41.93.8-0.10.90.5-1.3-1.4-1.6-1.50.1-1.41.81.81.91.9
Novel to familiar place preference ratio0.50.51.50.6-0.7-0.31.0-1.10.60.4-0.2-0.41.20.8-0.1-0.2
Novelty place preference0.20.21.10.3-0.3-0.00.6-0.80.30.0-0.6-0.11.00.70.0-0.0
Time in novel zone, NPP test0.20.20.80.2-0.3-0.00.5-0.70.2-0.1-0.5-0.00.90.60.10.1
Total zone transitions, NPP test1.21.84.61.9-1.4-1.61.1-2.10.50.51.0-1.21.41.80.60.8
Total locomotion distance, NPP test0.50.71.80.40.1-0.1-0.5-1.2-0.8-0.40.2-1.11.11.31.21.1
Locomotion velocity, NPP test0.40.61.70.30.1-0.1-0.3-1.2-0.7-0.20.0-0.91.11.31.11.0
Intraocular pressure1.31.83.9-1.80.82.00.01.70.40.3-0.81.6-0.8-1.9-1.5-1.7
Delta distance traveled before/after self-admin0.10.10.4-0.2-0.00.2-0.10.40.20.2-0.10.3-0.6-0.3-0.1-0.1
Delta ambulatory time before/after self-admin0.10.10.6-0.0-0.2-0.10.00.40.30.20.00.4-0.8-0.3-0.1-0.0
Parametrial fat weight2.14.17.8-2.12.82.5-2.70.1-2.8-2.5-1.5-0.41.70.82.11.8
Pavlov. Cond. lever latency0.30.41.0-0.70.30.5-0.21.00.1-0.1-1.01.0-0.9-0.8-0.4-0.3
Pavlov. Cond. magazine entry latency0.60.82.10.20.10.1-0.2-1.3-0.6-0.7-0.5-0.51.41.41.21.2
Pavlov. Cond. change in total contacts0.30.31.5-0.10.20.4-0.0-0.8-0.4-0.1-0.6-0.11.20.80.50.4
Pavlov. Cond. index score0.10.10.40.2-0.2-0.00.3-0.60.10.10.1-0.30.60.40.10.1
Pavlov. Cond. latency score0.10.10.50.2-0.0-0.00.0-0.7-0.2-0.10.2-0.40.70.60.40.4
Pavlov. Cond. lever contacts0.10.10.30.20.0-0.2-0.2-0.5-0.3-0.10.5-0.50.50.50.40.4
Pavlov. Cond. magazine entry number0.10.10.5-0.10.5-0.1-0.70.3-0.5-0.50.3-0.1-0.30.10.40.4
Pavlov. Cond. intertrial magazine entries0.40.51.4-0.70.60.6-0.31.1-0.00.2-1.20.7-0.6-0.9-0.5-0.7
Pavlov. Cond. lever-magazine prob. diff.0.20.20.80.4-0.4-0.20.4-0.90.10.20.2-0.50.80.70.20.2
Pavlov. Cond. response bias0.00.00.10.1-0.20.00.4-0.30.20.3-0.2-0.10.30.1-0.1-0.2
Pavlov. Cond. lever latency0.40.51.7-0.60.50.3-0.80.9-0.6-0.6-0.91.3-0.9-0.10.40.5
Pavlov. Cond. magazine entry latency1.61.94.52.1-1.7-1.91.5-2.10.91.00.7-1.01.21.40.20.4
Pavlov. Cond. change in total contacts0.81.13.11.1-1.0-0.61.4-1.80.80.8-0.0-1.11.80.9-0.1-0.2
Pavlov. Cond. index score1.11.53.41.6-1.4-1.21.5-1.90.91.10.8-1.51.50.9-0.2-0.2
Pavlov. Cond. latency score1.01.33.11.5-1.1-1.01.3-1.80.71.00.9-1.51.50.9-0.1-0.2
Pavlov. Cond. lever contacts0.50.71.20.5-0.8-0.31.1-0.31.10.90.9-0.80.3-0.6-1.0-1.1
Pavlov. Cond. magazine entry number2.73.37.3-2.72.52.4-2.42.6-1.6-1.5-0.91.2-1.5-1.60.2-0.0
Pavlov. Cond. intertrial magazine entries0.50.71.9-1.41.21.4-1.11.0-0.7-0.7-0.30.3-0.3-0.70.1-0.1
Pavlov. Cond. lever-magazine prob. diff.1.31.73.91.8-1.6-1.41.6-2.01.01.10.8-1.41.51.0-0.2-0.1
Pavlov. Cond. response bias0.91.22.51.3-1.4-1.01.6-1.21.21.10.9-1.10.80.2-0.7-0.6
Time in closed arm before self-admin0.10.10.60.10.10.10.2-0.4-0.0-0.10.0-0.40.80.2-0.0-0.1
Time in closed arm after self-admin0.10.10.30.30.2-0.3-0.5-0.2-0.3-0.20.3-0.40.10.40.50.5
Time in open arm before self-admin0.70.72.2-0.40.40.0-1.00.6-0.9-0.7-0.81.5-1.10.10.91.2
Time in open arm after self-admin0.50.52.0-0.7-0.00.40.11.00.10.1-0.91.4-1.1-0.9-0.5-0.4
Bone: periosteal estimation0.40.84.00.10.60.4-0.4-0.8-0.6-0.11.4-2.01.60.60.3-0.0
Bone: periosteal perimeter0.30.52.20.40.10.00.1-0.8-0.1-0.11.0-1.51.30.50.0-0.1
Bone: post-yield work4.86.622.00.51.00.5-1.2-3.5-2.1-2.1-0.2-3.04.73.73.02.8
Progressive ratio test 1 active lever presses1.71.83.7-1.81.91.8-1.61.3-1.5-1.7-1.61.0-0.1-0.70.40.3
Progressive ratio test 1 breakpoint1.51.63.1-1.71.81.7-1.41.4-1.2-1.5-1.40.9-0.3-0.80.20.0
Progressive ratio test 1 inactive lever presses1.01.12.7-1.21.31.1-1.30.7-1.2-1.3-1.60.9-0.2-0.10.80.8
Progressive ratio test 2 active lever presses2.52.76.3-2.32.52.4-2.01.5-1.7-1.8-1.81.20.3-0.90.40.1
Progressive ratio test 2 breakpoint3.03.47.0-2.62.62.6-2.02.1-1.6-1.6-2.11.7-0.3-1.40.1-0.3
Progressive ratio test 2 inactive lever presses5.96.813.4-3.53.73.5-3.02.1-2.8-3.0-3.42.40.4-0.91.10.7
Incentive Sensitization - Responses0.30.30.9-0.70.90.8-0.70.3-0.6-0.5-0.70.50.5-0.10.20.0
Incentive Sensitization - Breakpoint0.40.51.2-0.91.11.0-0.80.4-0.7-0.5-0.90.60.5-0.20.2-0.1
Sum of active levers in priming session hrs 5-63.33.28.20.7-1.5-0.42.30.32.52.71.5-0.6-0.4-1.4-2.7-2.9
Progressive ratio2.42.87.71.8-0.7-1.40.4-2.8-0.5-0.61.0-2.02.52.41.61.7
Food seeking constrained by brief footshock0.20.20.60.7-0.6-0.80.3-0.10.50.40.60.5-0.6-0.0-0.1-0.0
Seeking ratio, punishment vs. effort1.72.16.3-1.40.70.9-0.72.50.10.2-1.02.2-2.5-1.9-0.9-0.9
Retroperitoneal fat weight2.99.422.0-4.24.74.3-4.32.3-3.7-3.6-2.90.50.4-0.81.81.3
Reaction time number correct0.60.91.70.8-0.9-0.91.00.21.11.31.3-0.5-0.7-0.7-1.1-1.1
Reaction time mean minus median1.51.93.61.6-1.7-1.21.9-1.81.61.41.2-1.41.40.8-0.6-0.6
Reaction time mean minus median AUC1.01.42.81.3-1.4-1.11.7-1.01.51.51.2-1.00.5-0.0-1.0-1.0
Reaction time num false alarms0.20.21.30.10.2-0.5-0.60.6-0.40.30.30.4-1.1-0.40.20.2
Reaction time num false alarms AUC0.20.31.30.8-0.5-1.1-0.00.10.00.80.70.2-0.9-0.00.10.1
Reaction time trials correct on left0.60.91.70.8-0.9-0.91.00.21.11.31.3-0.5-0.7-0.7-1.1-1.1
Reaction time trials on left0.81.12.10.9-1.1-1.01.20.11.21.41.4-0.5-0.7-0.7-1.2-1.2
Reaction time mean0.10.10.3-0.4-0.10.50.4-0.20.40.1-0.50.30.5-0.1-0.2-0.2
Reaction time mean AUC0.10.10.5-0.40.10.60.2-0.30.2-0.0-0.70.30.70.00.0-0.1
Median of all reaction times0.20.20.8-0.80.40.8-0.10.1-0.1-0.3-0.90.60.4-0.10.20.1
Reaction time omissions0.60.81.71.3-1.3-1.21.3-1.10.81.30.7-0.10.40.5-0.3-0.2
Reaction time false alarm rate0.10.20.50.10.3-0.3-0.70.3-0.70.00.10.4-0.60.10.50.5
Reaction time premature initiation rate1.72.35.52.1-2.3-2.31.7-0.81.71.32.0-0.7-1.00.3-0.7-0.3
Reaction time premature initiations3.04.39.12.7-3.0-3.02.6-0.72.62.22.5-0.7-1.4-0.1-1.5-1.1
Std. dev. reaction times0.30.51.40.5-0.9-0.31.2-0.81.00.80.2-0.40.70.2-0.5-0.5
Reaction time trials completed0.81.12.10.9-1.1-1.01.20.11.21.41.4-0.5-0.7-0.7-1.2-1.2
Reaction time trials AUC0.50.81.70.8-0.8-0.90.90.21.01.11.3-0.5-0.7-0.6-1.0-1.0
Run reversals in cocaine runway, females2.01.94.61.2-0.1-1.1-0.7-1.9-1.2-0.80.5-1.41.32.22.02.1
Run reversals in cocaine runway, males1.31.33.1-0.5-0.10.30.41.50.91.20.70.3-1.6-1.8-1.6-1.7
Latency to leave start box in cocaine runway0.70.71.50.10.60.2-0.8-0.9-1.0-0.8-0.2-0.81.21.21.21.1
Latency to leave start box in cocaine runway, F0.40.41.00.00.30.0-0.4-0.7-0.8-0.5-0.9-0.10.81.00.90.9
Latency to leave start box in cocaine runway, M0.30.31.60.30.3-0.0-0.3-0.3-0.10.01.3-1.20.50.30.1-0.0
Std. dev. time between licks in bursts0.30.31.60.2-0.3-0.5-0.10.70.20.30.90.4-1.3-0.4-0.3-0.2
Total sessions with >9 infusions1.51.74.1-1.01.81.1-2.00.1-2.0-1.9-0.5-0.20.80.61.51.3
Short access day 1 total inactive lever presses2.52.85.4-2.12.32.1-2.31.1-2.0-2.0-1.91.60.1-0.31.21.0
Short access day 10 total inactive lever presses2.32.65.3-2.01.91.7-2.01.6-1.6-1.2-2.02.3-0.9-0.80.80.7
Short access day 1 total infusions3.53.77.9-1.52.41.6-2.6-0.1-2.8-2.7-1.7-0.31.41.02.32.1
Short access day 10 total infusions3.74.28.7-0.52.20.9-2.5-1.0-2.9-2.9-1.1-1.02.31.72.72.4
Short access total infusions2.22.55.7-0.71.90.9-2.1-0.5-2.3-2.4-0.7-0.51.51.12.01.8
Short access day 1 locomotion2.62.86.1-1.32.21.5-2.4-0.0-2.5-2.4-1.20.61.10.82.01.7
Short access day 10 total locomotion2.22.55.7-0.91.91.0-2.2-0.2-2.4-2.2-1.40.31.20.92.01.8
Short access total locomotion2.22.25.1-0.71.80.8-2.0-0.4-2.3-2.1-1.10.51.21.02.01.8
One hour access (0.3 mA shock)5.76.614.0-3.73.73.7-3.12.7-2.6-2.5-2.72.0-0.3-1.70.60.1
Compulsive drug intake1.71.74.71.7-2.2-2.01.7-0.51.71.50.9-0.4-1.20.1-0.6-0.2
One hour access (shock baseline)5.15.913.9-3.63.73.7-2.82.3-2.5-2.3-2.61.60.4-1.50.3-0.2
Social response proportion0.40.40.90.8-0.9-0.70.9-0.70.90.10.5-0.20.50.4-0.3-0.1
Social responses0.30.30.90.5-0.7-0.50.80.11.00.30.60.4-0.5-0.4-0.7-0.5
Social time0.40.61.30.6-1.0-0.60.90.11.00.61.10.3-0.7-0.4-0.8-0.7
Soleus weight1.95.613.6-3.73.53.6-3.22.5-2.6-1.9-2.11.1-0.6-1.20.90.5
Bone: stiffness1.72.77.52.0-1.3-1.51.2-2.70.60.41.3-2.42.42.00.60.6
Tibialis anterior weight6.923.841.26.4-6.3-6.06.2-4.05.25.86.4-4.30.91.2-3.1-2.8
Time to tail flick, vehicle, before self-admin0.60.61.60.9-0.3-0.80.2-1.1-0.1-0.10.8-1.21.10.90.40.4
Time to tail flick, vehicle, after self-admin1.41.53.21.6-0.9-1.50.3-1.8-0.2-0.01.5-1.81.01.60.91.1
Time to tail flick, test, before self-admin1.71.63.5-0.31.30.3-1.7-0.6-1.8-1.6-0.4-0.71.01.21.91.8
Time to tail flick, test, after self-admin0.10.10.2-0.1-0.20.00.30.20.30.20.2-0.1-0.3-0.3-0.4-0.4
Delta time to tail flick, vehicle, before/after SA0.40.40.80.7-0.5-0.70.1-0.9-0.1-0.00.7-0.70.30.90.50.7
Delta time to tail flick, test, before/after SA3.02.75.70.5-1.7-0.72.20.82.32.00.70.7-1.5-1.6-2.4-2.2
Tibia length1.13.16.21.3-1.6-0.72.4-0.82.12.52.0-1.80.8-0.7-2.2-2.4
Ambulatory time before self-admin0.30.30.70.3-0.40.00.8-0.60.60.60.4-0.90.90.1-0.5-0.6
Ambulatory time after self-admin0.30.31.0-0.70.51.0-0.3-0.3-0.3-0.4-1.0-0.10.90.40.40.3
Bone: tissue strength0.00.00.2-0.00.00.20.1-0.30.1-0.1-0.3-0.30.50.20.00.0
Total heroin consumption2.93.47.12.7-2.6-2.52.4-2.11.92.11.8-1.10.71.2-0.6-0.4
Bone: trabecular number0.71.13.80.8-0.0-0.30.0-1.6-0.3-1.0-0.1-1.51.91.41.01.0
Bone: trabecular spacing0.20.20.9-0.30.20.0-0.40.7-0.3-0.0-0.30.9-1.0-0.30.10.2
Bone: trabecular thickness0.81.02.3-0.61.10.7-1.2-0.2-1.2-1.5-1.30.00.90.71.21.1
Bone: trabecular tissue density1.82.56.7-2.62.12.4-1.62.1-1.2-0.6-1.61.2-0.8-1.4-0.1-0.4
Water consumed over 24 hours0.50.61.50.9-1.2-1.21.1-0.10.90.4-0.51.0-0.6-0.2-0.4-0.1
Number of responses in last shaping day0.80.92.7-1.00.90.7-0.91.3-0.6-0.8-0.91.6-1.0-0.9-0.0-0.0