Ehbp1l1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_039079580.2 0.03 0.02 3.5e-03 0.01 0.01 0.01 0.01 9.3e-03 3.4e-02 6.3e-02 1.0e-02
2 PL intron excision ratio chr1_212426531_212426697 0.03 0.02 5.2e-03 0.01 0.01 0.01 0.01 2.2e-02 1.1e-02 1.6e-02 1.7e-02
3 Adipose gene expression Ehbp1l1 0.28 0.11 0.0e+00 0.16 0.2 0.2 0.2 5.9e-17 5.2e-22 2.9e-21 1.1e-21
4 NAcc gene expression Ehbp1l1 0.1 0.05 1.1e-15 0.1 0.1 0.1 0.1 1.2e-15 3.1e-15 9.9e-15 3.3e-15
5 BLA gene expression Ehbp1l1 0.1 0.06 2.5e-04 0.06 0.04 0.04 0.04 2.7e-04 2.7e-03 4.6e-03 2.9e-03
6 Brain isoform ratio NM_001129997.1 0.08 0.04 2.8e-05 0.06 0.05 0.06 0.06 2.5e-06 1.9e-05 2.0e-06 1.1e-06
7 pVTA isoform ratio NM_001129997.1 0.05 0.03 1.2e-03 0.04 0.03 0.03 0.03 2.9e-04 1.1e-03 1.5e-03 1.4e-03
8 Liver gene expression Ehbp1l1 0.03 0.02 9.3e-03 0 0 0 0.01 7.7e-02 9.9e-02 7.6e-02 4.9e-02
9 IC gene expression Ehbp1l1 0.22 0.11 5.3e-07 0.14 0.16 0.17 0.15 1.8e-06 2.7e-07 1.6e-07 6.1e-07
10 Brain gene expression Ehbp1l1 0.17 0.08 4.4e-10 0.1 0.11 0.12 0.12 2.9e-09 1.8e-10 4.7e-11 4.0e-11
11 PL gene expression Ehbp1l1 0.14 0.07 2.0e-12 0.07 0.12 0.12 0.12 1.6e-08 3.1e-13 1.6e-12 1.7e-12
12 Adipose intron excision ratio chr1_212434005_212436456 0.08 0.06 1.6e-04 0.02 0.02 0.03 0.02 1.1e-03 2.2e-03 3.0e-04 2.8e-03
13 OFC gene expression Ehbp1l1 0.46 0.17 2.9e-05 0.15 0.16 0.26 0.2 2.2e-04 1.6e-04 6.3e-07 2.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density1.42.34.70.9-0.3-2.00.71.9-2.2-1.8-2.01.51.51.41.21.2
Area under the delay curve0.81.02.0-0.3-0.8-0.61.20.9-1.0-0.8-0.41.11.41.4-0.61.4
BMI with tail4.114.027.12.6-0.3-5.01.54.4-5.1-4.9-5.23.63.03.13.23.1
BMI without tail1.44.28.91.8-0.3-3.01.02.4-2.5-2.1-2.82.22.12.30.91.6
Body weight1.77.217.23.82.0-4.2-1.22.7-3.4-3.3-4.00.90.60.63.10.5
Weight adjusted by age0.60.92.61.51.6-0.7-1.50.2-0.5-0.6-0.3-0.7-1.0-1.10.6-0.5
Bone surface3.15.611.23.01.9-3.3-1.32.8-3.3-3.2-2.90.60.4-0.12.81.2
Bone volume2.03.57.51.80.8-2.6-0.32.5-2.7-2.6-2.31.10.80.52.21.4
Breakpoint value in progressive ratio session1.21.55.02.21.7-1.7-1.31.4-0.9-1.0-0.9-0.2-0.6-0.60.9-0.1
Number of licking bursts0.10.20.60.80.6-0.6-0.50.4-0.4-0.4-0.2-0.1-0.3-0.30.20.0
Context. condit. distance diff. score0.91.13.6-1.9-1.71.01.5-0.50.91.00.40.70.71.0-0.7-0.1
Locomotion velocity, session 10.20.20.8-0.00.10.4-0.2-0.80.50.50.1-0.6-0.3-0.2-0.2-0.9
Locomotion distance, session 10.91.22.60.8-0.3-1.50.61.1-1.5-1.2-1.61.01.11.30.50.7
Locomotion velocity, session 21.51.74.12.01.0-2.0-0.51.4-1.7-1.7-1.70.20.10.31.30.4
Locomotion distance, session 20.70.92.31.10.0-1.50.31.0-1.2-0.9-1.40.81.01.10.20.5
Locomotion velocity, session 31.11.22.6-0.4-1.1-0.71.20.6-1.2-1.3-1.61.31.01.31.40.6
Locomotion distance, session 30.00.00.1-0.1-0.20.00.2-0.20.00.1-0.20.1-0.00.20.2-0.2
Stereotopy head waving bouts, day 31.21.42.7-1.0-1.6-0.41.50.3-1.0-1.0-1.51.41.61.60.90.5
Stereotopy head waving duration, day 30.70.81.8-1.1-1.30.01.20.3-0.6-0.6-0.71.11.31.10.10.5
Locomotion velocity, session 72.32.54.5-0.5-1.5-1.11.81.4-1.7-1.8-1.42.01.61.90.92.1
Locomotion distance, session 70.60.81.7-0.1-0.8-0.70.90.5-1.0-1.0-1.01.01.01.30.31.0
Stereotopy head waving bouts, day 70.50.61.3-0.2-0.4-0.60.51.1-1.0-1.1-0.51.10.70.50.41.0
Stereotopy head waving duration, day 70.81.02.50.80.4-1.40.01.6-1.5-1.4-0.90.90.60.40.31.0
Locomotion velocity, session 80.60.72.11.11.0-0.2-1.1-0.70.20.4-0.4-1.2-0.9-0.70.5-1.5
Locomotion distance, session 80.50.81.4-0.7-1.1-0.51.20.5-0.6-0.6-1.21.10.91.20.80.3
Degree of sensitization distance0.90.91.90.1-0.7-0.90.70.7-1.2-1.2-1.40.91.01.10.90.9
Degree of sensitization stereotypy0.60.61.90.70.5-1.1-0.21.4-1.0-1.2-0.50.70.10.00.60.8
Conditioned locomotion0.60.72.11.41.2-0.9-1.00.3-0.5-0.7-0.9-0.6-0.6-0.60.8-0.4
Cocaine response after cond. corrected0.50.61.8-1.3-1.30.91.2-1.00.40.20.10.40.60.7-0.1-0.1
Cocaine response after cond. not corrected0.40.41.3-1.1-1.10.80.9-0.90.1-0.1-0.10.30.60.60.2-0.0
Cocaine response before conditioning0.40.41.21.11.0-0.7-0.90.7-0.7-0.7-0.1-0.1-0.3-0.60.40.4
Saline control response1.41.96.52.62.0-1.6-1.80.4-1.5-1.5-1.2-0.7-0.6-0.70.80.1
Bone: connectivity density2.13.37.32.10.8-2.6-0.32.2-2.7-2.3-2.41.01.00.81.61.2
Bone: cortical apparent density0.50.72.10.20.60.3-0.5-0.31.11.31.2-0.6-0.7-0.5-1.4-0.6
Bone: cortical area0.60.93.61.31.1-0.8-1.00.5-0.8-1.2-0.7-0.4-0.7-0.81.90.2
Bone: cortical porosity0.20.20.60.40.0-0.70.10.7-0.5-0.3-0.50.40.80.5-0.10.2
Bone: cortical porosity0.30.31.00.80.3-1.0-0.10.8-0.7-0.4-0.80.30.60.40.10.0
Bone: cortical thickness1.62.76.82.62.6-0.5-2.4-0.60.60.40.4-1.9-2.3-1.90.5-1.3
Bone: cortical thickness0.80.91.71.01.00.3-1.0-1.11.01.20.6-1.2-1.2-0.8-0.4-1.3
Bone: cortical tissue density0.60.82.30.40.70.3-0.7-0.31.11.31.2-0.8-0.8-0.6-1.5-0.8
Condit. Reinf. active minus inactive responses0.30.30.90.4-0.0-0.70.20.6-0.7-0.6-0.30.50.50.6-0.21.0
Condit. Reinf. active-inactive response ratio0.20.21.20.10.0-0.10.10.2-0.2-0.10.60.20.20.2-1.10.9
Condit. Reinf. active responses0.40.50.80.3-0.3-0.80.50.9-0.8-0.8-0.80.80.60.70.70.9
Condit. Reinf. inactive responses0.70.83.20.0-0.7-0.70.80.9-0.7-0.9-1.40.90.70.71.80.3
Incentive salience index mean0.80.91.60.6-0.2-1.30.41.1-1.2-1.2-1.11.00.90.90.61.2
Condit. Reinf. lever presses0.81.23.50.80.3-1.4-0.11.3-1.2-1.5-1.60.80.40.31.90.8
Condit. Reinf. active minus inactive responses0.10.20.7-0.1-0.2-0.10.00.4-0.6-0.7-0.00.50.20.00.30.8
Condit. Reinf. active-inactive response ratio0.60.72.5-0.7-0.8-0.10.60.7-0.9-1.3-0.60.90.50.21.61.1
Condit. Reinf. active responses0.20.30.70.50.1-0.7-0.00.8-0.8-0.6-0.10.60.50.3-0.50.8
Condit. Reinf. inactive responses0.30.42.70.90.3-0.8-0.10.5-0.40.20.00.40.60.7-1.60.2
Condit. Reinf. lever presses1.11.53.82.01.5-1.7-1.21.4-1.4-1.5-1.0-0.1-0.4-0.61.30.6
Condit. Reinf. lever reinforcers received0.20.30.70.80.5-0.8-0.40.8-0.8-0.6-0.00.30.20.0-0.50.8
Conditioned reinforcement - actives0.30.52.00.10.80.3-0.9-0.2-0.1-0.40.1-0.6-1.0-1.40.9-0.2
Conditioned reinforcement - inactives0.71.03.8-2.0-1.21.70.8-0.81.00.91.40.20.0-0.4-0.6-0.1
Conditioned locomotion2.63.310.6-3.3-2.22.91.7-1.91.81.52.30.20.2-0.1-1.50.3
Patch foraging indifference point 0 sec0.00.10.2-0.1-0.3-0.10.20.3-0.4-0.4-0.00.30.30.3-0.10.4
Patch foraging indifference point AUC0.91.44.21.92.1-1.0-1.80.7-0.2-0.1-0.2-1.0-1.4-1.40.3-0.6
Delay disc. indifference point, 0s delay1.41.63.4-1.0-1.4-0.51.80.8-1.0-0.9-0.81.41.81.8-0.51.5
Delay disc. indifference point, 16s delay0.60.61.6-0.7-1.10.01.20.5-0.2-0.10.21.11.01.0-0.61.0
Delay disc. indifference point, 2s delay0.60.61.8-0.4-0.6-0.30.80.5-1.0-1.2-0.60.80.70.70.51.3
Delay disc. indifference point, 24s delay0.10.10.5-0.3-0.10.50.2-0.50.40.40.5-0.30.10.1-0.7-0.1
Delay disc. indifference point, 4s delay0.80.81.9-0.5-0.9-0.31.20.4-0.8-0.6-0.60.91.41.4-0.51.2
Delay disc. indifference point, 8s delay0.30.41.2-0.3-0.6-0.30.90.4-0.3-0.1-0.10.61.11.1-0.90.4
Indifference point function ln k2.34.112.1-3.5-3.42.52.9-1.81.41.21.11.21.51.8-0.60.3
Indifference point function log k2.34.112.1-3.5-3.42.52.9-1.81.41.21.11.21.51.8-0.60.3
Patch foraging total patch changes 0 sec0.00.00.10.0-0.00.2-0.2-0.30.10.10.3-0.2-0.2-0.1-0.2-0.2
Patch foraging total patch changes 12 sec1.41.87.32.72.0-2.1-1.51.4-1.0-0.7-1.1-0.4-0.7-0.50.3-0.3
Patch foraging total patch changes 18 sec0.30.41.11.00.6-1.0-0.31.0-0.8-0.7-0.70.2-0.1-0.00.50.3
Patch foraging total patch changes 24 sec0.71.33.71.71.9-0.6-1.9-0.0-0.4-0.5-0.2-1.3-1.3-1.40.4-0.4
Patch foraging total patch changes 6 sec0.40.62.01.40.8-1.1-0.60.6-1.0-0.8-0.9-0.1-0.20.00.60.1
Patch foraging time to switch 0 sec1.94.08.61.70.3-2.90.52.9-2.7-2.6-2.51.71.41.31.41.6
Patch foraging water rate 0 sec2.45.112.4-2.6-1.13.50.1-3.23.23.02.8-1.3-1.2-1.1-0.9-1.7
Patch foraging water rate 12 sec3.98.121.0-3.8-2.34.61.2-4.23.73.73.3-1.2-0.5-0.5-1.7-1.7
Patch foraging water rate 18 sec1.32.15.2-2.2-1.62.30.9-2.21.71.71.1-0.40.10.2-0.5-0.9
Patch foraging water rate 24 sec2.53.69.0-2.9-1.53.00.6-2.72.62.41.8-0.7-0.5-0.5-0.3-1.5
Patch foraging water rate 6 sec2.84.110.6-2.5-1.53.30.5-3.22.82.72.0-1.0-0.6-0.4-0.4-1.6
Seeking ratio, delayed vs. immediate footshock0.70.91.7-0.4-0.9-0.51.00.9-0.9-0.8-0.01.31.31.3-1.01.1
Distance traveled before self-admin0.60.72.20.90.5-1.3-0.11.5-1.2-1.1-0.80.60.30.20.70.7
Distance traveled after self-admin0.10.20.40.40.6-0.3-0.50.4-0.3-0.30.4-0.1-0.3-0.3-0.40.6
Extensor digitorum longus weight2.911.235.56.04.5-4.8-3.42.9-2.9-3.3-3.7-0.9-1.4-1.23.1-0.1
Bone: elastic displacement2.02.35.6-0.8-0.22.0-0.3-2.42.32.21.5-1.3-1.0-0.9-0.5-1.9
Bone: elastic work0.81.02.91.31.1-0.0-1.2-1.01.01.00.0-1.2-1.0-0.80.4-1.7
Bone: endosteal estimation1.63.55.6-1.3-2.1-0.82.01.4-1.8-1.9-2.32.12.41.92.31.5
Bone: endosteal perimeter1.94.16.5-1.5-2.1-0.72.01.6-2.3-2.6-2.02.22.31.72.42.2
Epididymis fat weight0.82.813.0-3.6-2.82.12.3-0.91.00.50.61.01.00.61.00.2
Delta time in closed arm before/after self-admin0.20.20.80.20.0-0.1-0.1-0.60.30.6-0.4-0.30.00.3-0.1-0.9
Delta time in open arm before/after self-admin0.20.20.80.50.8-0.2-0.60.5-0.0-0.20.3-0.4-0.6-0.90.30.2
Diff in mean of infusions in LGA sessions0.30.30.90.90.9-0.3-0.9-0.10.00.1-0.1-0.7-0.8-0.60.1-0.6
Delay discount exponential model param0.60.71.70.20.60.6-1.0-0.70.90.80.4-0.9-1.2-1.20.6-1.3
Extinction: sum of active levers before priming1.81.94.42.00.9-2.1-0.61.8-1.9-1.9-1.50.70.30.40.81.3
Active lever presses in extinction session 61.91.94.02.02.0-1.4-1.80.9-0.8-1.1-1.2-0.8-1.2-1.31.9-0.3
Bone: final force1.22.04.22.11.6-1.9-1.31.2-1.4-1.5-1.8-0.2-0.3-0.52.00.1
Bone: final moment1.11.84.02.01.5-1.8-1.21.1-1.4-1.4-1.7-0.2-0.3-0.52.0-0.0
Food consumed during 24 hour testing period0.50.61.70.20.90.7-0.9-0.60.30.01.1-1.1-1.2-1.3-0.3-0.1
Glucose2.23.58.2-2.1-2.8-0.02.90.8-1.0-0.9-1.12.42.62.50.11.3
Heart weight2.33.68.3-1.5-2.6-0.72.70.9-1.3-1.0-1.92.42.92.90.51.0
Delay discount hyperbolic model param0.70.82.10.20.70.6-1.0-0.81.00.90.5-1.0-1.2-1.20.4-1.4
Intermittent access intake day 1-15 change0.30.72.0-1.4-0.51.40.1-0.91.00.71.2-0.3-0.5-0.8-0.4-0.3
Intermittent access intake escalation0.30.71.9-1.3-0.31.4-0.1-0.91.00.71.1-0.4-0.7-1.0-0.2-0.4
Intermittent access intake escalation 20.50.61.7-1.3-0.31.3-0.1-0.70.90.51.2-0.4-0.6-0.9-0.3-0.1
Intermitt. access day 1 inactive lever presses0.10.32.0-0.5-0.20.50.1-0.10.70.70.70.0-0.1-0.1-1.4-0.1
Intermitt. access day 15 inactive lever presses0.30.62.0-1.4-1.30.81.20.10.50.50.50.80.50.3-0.30.1
Intermitt. access escalation Index1.31.84.8-2.0-2.21.12.1-0.50.40.50.91.21.51.5-0.90.9
Intermittent access day 1 total infusions2.13.37.9-1.7-2.6-0.32.81.0-1.3-1.1-1.22.52.52.10.81.6
Intermittent access day 15 total infusions1.11.66.2-2.5-2.31.51.9-0.50.30.20.51.20.90.50.20.7
Intermittent access terminal intake (last 3 days)1.31.75.1-2.2-2.20.92.10.0-0.2-0.4-0.21.51.20.70.90.9
Intermittent access total infusions1.72.05.3-1.8-2.30.42.30.4-0.7-0.7-0.71.81.61.21.01.2
Intermittent access day 1 locomotion1.51.95.0-1.5-2.1-0.02.20.6-0.8-0.6-0.71.91.81.60.21.3
Intermittent access day 15 total locomotion0.81.45.0-2.2-2.11.11.9-0.00.0-0.10.41.41.00.60.11.0
Intermittent access total locomotion2.63.18.5-2.7-2.90.72.90.5-0.5-0.6-0.22.31.91.40.61.7
Intermittent access standard deviation0.40.82.2-1.5-0.71.50.4-1.01.11.11.0-0.3-0.3-0.5-0.7-0.6
Left kidney weight0.31.54.2-2.1-1.90.42.00.3-0.1-0.4-0.31.41.31.20.61.0
Right kidney weight0.10.42.2-1.5-0.80.90.7-0.50.50.10.30.10.2-0.10.50.1
Cocaine induced anxiety0.00.10.10.30.3-0.2-0.20.3-0.2-0.4-0.00.1-0.1-0.3-0.00.3
Post-drug Anxiety0.40.51.21.10.9-0.7-0.80.5-0.7-0.9-0.5-0.2-0.5-0.50.70.1
Baseline Anxiety0.20.20.50.70.6-0.1-0.7-0.3-0.00.0-0.1-0.6-0.5-0.30.1-0.6
Tail length0.41.73.21.31.70.2-1.8-1.11.21.30.7-1.8-1.3-1.3-0.8-1.6
Length with tail0.83.59.63.13.0-1.2-2.9-0.30.00.0-0.8-2.1-1.9-1.80.9-2.0
Length without tail1.03.17.42.72.7-0.9-2.6-0.6-0.1-0.0-0.8-2.1-1.9-1.81.3-2.1
Times rat made contact with spout0.20.21.40.80.4-0.6-0.10.2-0.10.30.1-0.00.20.4-1.20.0
Lifetime Intake1.31.64.5-1.5-2.10.22.10.3-0.7-0.6-0.81.71.61.31.01.0
Liver weight, left0.30.61.8-1.3-1.01.10.7-1.20.60.40.10.10.30.20.5-0.5
Liver weight, right0.91.54.7-2.2-2.01.61.5-1.70.90.90.20.20.70.8-0.2-0.7
Locomotor activity1.62.56.8-1.7-1.12.40.4-2.62.12.31.4-0.9-0.5-0.3-0.9-1.5
Locomotor testing distance1.83.39.0-1.9-1.32.70.6-3.02.42.71.6-1.0-0.5-0.2-1.0-1.8
Locomotor testing rearing1.32.65.4-1.9-1.52.30.9-2.31.82.21.5-0.50.30.3-1.8-1.2
Locomotion in novel chamber1.41.87.9-2.8-2.21.81.9-0.91.00.90.80.60.70.5-0.1-0.1
Locomotion in novel chamber post-restriction0.71.24.0-2.0-1.71.41.5-0.40.90.91.00.60.70.5-0.50.5
Fecal boli incidents, locomotor time 10.20.30.80.30.4-0.2-0.20.7-0.5-0.90.20.1-0.6-0.60.80.5
Change in fecal boli incidents, locomotor task0.30.30.9-0.2-0.6-0.30.5-0.1-0.00.3-1.00.40.80.80.1-0.3
Time >=10cm from walls, locomotor time 11.81.93.6-0.9-1.4-0.91.51.5-1.2-1.3-1.51.91.51.21.51.1
Bouts of movement, locomotor time 11.01.23.01.21.7-0.4-1.50.8-0.3-0.41.2-0.8-0.7-1.0-1.70.9
Total resting periods, locomotor time 10.80.81.91.01.4-0.5-1.20.9-0.4-0.61.0-0.5-0.5-0.8-1.31.1
Rest time, locomotor task time 10.40.51.8-1.3-0.71.30.5-0.70.90.70.8-0.2-0.2-0.3-0.1-0.2
Distance moved, locomotor task time 10.60.81.70.3-0.4-1.10.80.8-1.3-1.1-1.11.11.01.10.40.7
Vertical activity count, locomotor time 10.20.41.1-1.0-1.10.70.9-0.50.20.20.50.50.50.6-0.20.0
Time >=10cm from walls, locomotor time 20.10.10.5-0.10.3-0.4-0.10.7-0.2-0.40.10.2-0.1-0.20.10.3
Bouts of movement, locomotor time 20.20.31.10.90.7-0.6-0.60.7-0.3-0.20.4-0.10.1-0.0-1.10.5
Total resting periods, locomotor time 20.10.31.00.60.3-0.5-0.20.8-0.3-0.20.30.20.30.2-1.00.7
Rest time, locomotor task time 20.81.03.7-1.9-1.61.01.5-0.20.70.60.30.60.90.7-0.10.4
Distance moved, locomotor task time 20.40.51.71.21.3-0.5-1.1-0.0-0.4-0.40.0-0.7-0.9-0.7-0.1-0.2
Vertical activity count, locomotor time 21.11.53.00.10.61.2-1.1-1.71.41.41.1-1.4-1.4-1.1-0.3-1.7
Light reinforcement 10.10.30.8-0.3-0.00.7-0.2-0.70.70.90.9-0.4-0.2-0.3-0.9-0.4
Light reinforcement 20.20.30.8-0.9-0.40.80.1-0.20.1-0.30.50.1-0.3-0.50.90.5
Bone: marrow area1.73.86.2-1.4-2.2-0.82.11.4-1.8-1.9-2.32.22.52.02.21.6
Bone: maximum diameter0.61.26.00.50.7-0.5-0.70.5-1.3-1.9-1.0-0.2-0.4-0.82.40.7
Bone: maximum force2.54.59.12.51.5-3.0-0.92.5-2.7-2.8-2.90.80.30.12.91.0
Bone: maximum moment2.34.18.32.41.4-2.9-0.82.4-2.6-2.6-2.80.70.40.22.80.9
Mean time between licks in bursts0.10.30.90.50.40.1-0.6-0.90.40.5-0.1-0.7-0.4-0.1-0.3-0.9
Mean num. licks in bursts0.20.41.6-0.6-0.60.40.6-0.30.40.70.50.20.60.6-1.30.0
Cd content in liver0.30.31.3-1.1-0.80.80.60.20.20.20.80.30.3-0.0-0.40.5
Co content in liver2.83.37.9-1.4-0.42.2-0.1-2.22.72.82.4-1.2-0.9-0.6-2.3-1.4
Cu content in liver0.30.30.80.1-0.4-0.50.80.7-0.10.20.10.90.40.8-0.80.5
Fe content in liver0.40.41.50.50.60.1-0.7-0.60.0-0.1-0.5-0.7-0.7-0.71.2-1.0
K content in liver0.80.81.90.7-0.0-1.20.20.8-1.2-1.2-1.40.70.60.81.20.4
Mg content in liver0.40.41.2-0.6-1.0-0.01.00.1-0.10.0-0.40.90.91.10.00.1
Mn content in liver1.61.74.82.21.9-1.5-1.60.9-1.0-1.2-1.0-0.6-1.0-1.11.6-0.1
Na content in liver0.80.81.70.71.10.2-1.2-0.60.60.40.1-1.1-1.3-1.20.9-1.2
Rb content in liver1.01.13.0-1.5-1.70.91.5-0.70.30.60.60.91.21.3-1.00.4
Se content in liver0.00.10.3-0.2-0.20.20.10.2-0.2-0.20.20.20.1-0.20.60.3
Sr content in liver1.51.33.91.62.0-0.4-1.8-0.10.0-0.20.3-1.4-1.4-1.50.2-0.5
Zn content in liver0.10.10.30.50.2-0.6-0.00.5-0.10.0-0.10.30.10.4-0.50.1
Bone: minimum diameter2.24.07.2-1.0-2.1-1.12.31.9-2.0-1.9-1.82.62.72.31.42.2
Time in familiar zone, hab. session 10.40.40.8-0.4-0.8-0.20.80.4-0.5-0.5-0.40.90.60.80.40.7
Time in novel zone, hab. session 10.80.81.9-0.60.01.1-0.3-1.41.21.30.8-1.0-0.5-0.5-0.6-1.2
Total zone transitions, hab. session 10.20.31.31.10.6-1.1-0.20.9-0.4-0.2-0.40.40.00.3-0.20.3
Total locomotion distance, hab. session 10.50.71.4-0.7-1.0-0.41.20.7-0.5-0.7-0.81.20.91.10.50.8
Locomotion velocity, hab. session 10.30.50.9-0.2-0.5-0.70.80.8-0.6-0.7-0.81.00.60.80.30.6
Time in familiar zone, hab. session 20.40.41.8-0.10.10.7-0.4-1.30.70.60.1-0.8-0.5-0.30.2-1.1
Time in novel zone, hab. session 20.40.51.50.2-0.1-0.80.41.2-0.7-0.5-0.20.80.70.6-0.61.0
Total zone transitions, hab. session 22.12.66.01.3-0.1-2.40.62.1-2.1-1.5-2.11.61.91.80.21.1
Total locomotion distance, hab. session 21.62.03.9-0.2-1.2-1.41.41.4-1.5-1.2-1.81.81.92.00.41.1
Locomotion velocity, hab. session 21.72.33.8-0.4-1.3-1.31.61.5-1.5-1.4-1.91.92.02.00.71.2
Novel to familiar place preference ratio0.70.72.61.11.0-1.2-0.61.6-0.9-0.9-0.40.2-0.1-0.30.40.8
Novelty place preference0.40.42.00.70.6-0.9-0.31.4-0.7-0.7-0.20.30.1-0.10.00.8
Time in novel zone, NPP test0.30.31.50.60.5-0.8-0.31.2-0.6-0.6-0.20.30.1-0.1-0.00.7
Total zone transitions, NPP test1.01.54.61.81.0-2.1-0.51.7-1.4-1.2-1.60.40.50.40.60.4
Total locomotion distance, NPP test0.60.81.40.1-0.5-1.10.81.0-0.9-0.8-1.21.11.11.20.40.7
Locomotion velocity, NPP test0.50.71.30.3-0.4-1.10.71.1-0.8-0.7-1.01.11.01.10.20.8
Intraocular pressure0.91.33.0-1.3-0.01.7-0.3-1.21.41.21.7-0.8-1.0-1.3-0.9-0.7
Delta distance traveled before/after self-admin0.60.61.7-0.4-0.01.0-0.4-1.30.91.01.0-0.7-0.5-0.3-1.1-0.4
Delta ambulatory time before/after self-admin0.50.61.4-0.10.20.8-0.5-1.20.91.00.9-0.8-0.6-0.4-1.0-0.5
Parametrial fat weight1.43.310.2-3.2-3.11.12.80.1-0.1-0.4-0.02.12.11.80.11.3
Pavlov. Cond. lever latency0.30.41.1-0.6-0.11.0-0.0-0.90.40.51.0-0.6-0.4-0.4-0.8-0.1
Pavlov. Cond. magazine entry latency0.81.12.90.4-0.2-1.50.51.7-1.0-0.9-1.11.31.11.00.21.1
Pavlov. Cond. change in total contacts0.50.62.40.30.0-1.00.31.5-0.6-0.7-0.41.00.50.40.21.1
Pavlov. Cond. index score0.10.20.80.40.3-0.8-0.20.9-0.2-0.2-0.40.40.10.10.20.2
Pavlov. Cond. latency score0.20.20.80.30.1-0.80.10.9-0.2-0.3-0.70.60.40.40.40.2
Pavlov. Cond. lever contacts0.30.41.00.3-0.2-0.90.30.8-0.4-0.4-1.00.80.60.70.70.2
Pavlov. Cond. magazine entry number0.10.20.5-0.6-0.70.60.5-0.7-0.2-0.1-0.1-0.00.30.30.2-0.1
Pavlov. Cond. intertrial magazine entries0.30.41.6-0.4-0.21.00.1-0.70.70.61.3-0.3-0.4-0.5-0.50.2
Pavlov. Cond. lever-magazine prob. diff.0.30.41.40.60.4-1.1-0.11.2-0.5-0.5-0.60.60.30.30.30.5
Pavlov. Cond. response bias0.10.10.40.50.5-0.6-0.40.70.0-0.0-0.10.2-0.2-0.20.10.1
Pavlov. Cond. lever latency0.60.82.1-1.0-1.00.70.9-0.60.91.30.60.30.70.8-1.4-0.3
Pavlov. Cond. magazine entry latency1.92.37.02.61.7-2.4-1.12.0-1.8-1.6-1.30.2-0.1-0.10.70.7
Pavlov. Cond. change in total contacts1.11.84.01.81.3-1.8-0.92.0-1.7-2.0-0.80.5-0.2-0.40.91.4
Pavlov. Cond. index score1.52.14.62.11.5-2.0-1.11.8-1.8-2.0-1.20.2-0.3-0.41.31.0
Pavlov. Cond. latency score1.52.04.02.01.4-1.9-0.91.8-1.8-2.0-1.30.3-0.3-0.41.51.0
Pavlov. Cond. lever contacts0.50.71.51.01.0-0.7-0.90.7-0.9-1.2-0.5-0.3-0.6-0.71.20.3
Pavlov. Cond. magazine entry number2.93.511.3-3.4-2.62.81.8-2.32.12.01.20.10.60.7-0.7-0.9
Pavlov. Cond. intertrial magazine entries0.30.41.8-1.4-0.91.10.6-0.60.60.40.50.10.10.10.0-0.1
Pavlov. Cond. lever-magazine prob. diff.1.72.35.52.31.7-2.1-1.21.9-1.9-2.1-1.20.2-0.3-0.41.21.1
Pavlov. Cond. response bias1.21.63.71.91.5-1.7-1.11.4-1.6-1.7-1.00.0-0.4-0.51.10.7
Time in closed arm before self-admin0.20.20.5-0.5-0.6-0.10.60.7-0.3-0.4-0.20.70.50.30.40.6
Time in closed arm after self-admin0.10.20.6-0.4-0.70.20.5-0.20.00.0-0.20.50.40.60.20.3
Time in open arm before self-admin0.50.62.2-0.5-0.60.80.5-1.30.60.80.6-0.20.20.7-1.5-0.4
Time in open arm after self-admin0.20.20.60.20.40.2-0.2-0.40.50.70.5-0.6-0.3-0.2-0.8-0.5
Bone: periosteal estimation0.91.97.80.0-0.5-1.00.51.2-1.6-2.0-1.91.00.90.52.81.1
Bone: periosteal perimeter1.01.74.90.4-0.0-1.10.21.2-1.9-2.2-1.60.80.60.32.21.3
Bone: post-yield work7.911.622.40.8-1.2-3.82.14.7-4.4-4.3-3.93.83.22.92.73.7
Progressive ratio test 1 active lever presses0.00.10.2-0.2-0.40.20.4-0.0-0.00.1-0.20.30.2-0.00.40.0
Progressive ratio test 1 breakpoint0.00.00.2-0.1-0.30.20.30.0-0.00.1-0.20.20.1-0.10.4-0.0
Progressive ratio test 1 inactive lever presses0.10.10.8-0.2-0.10.30.1-0.00.40.60.4-0.1-0.0-0.2-0.9-0.2
Progressive ratio test 2 active lever presses0.50.52.0-1.4-1.30.91.1-0.30.20.20.30.60.60.10.20.3
Progressive ratio test 2 breakpoint0.40.51.9-1.4-1.31.01.0-0.40.30.30.40.50.40.00.20.2
Progressive ratio test 2 inactive lever presses1.82.810.2-3.2-2.72.02.4-0.70.90.91.41.31.30.8-1.00.8
Incentive Sensitization - Responses0.30.41.00.1-0.4-0.60.40.7-0.9-0.9-0.80.80.60.41.00.5
Incentive Sensitization - Breakpoint0.30.40.8-0.1-0.5-0.40.60.6-0.8-0.8-0.70.80.60.40.90.6
Sum of active levers in priming session hrs 5-63.43.19.11.32.40.5-2.7-0.60.80.10.9-2.1-2.8-3.01.2-1.2
Progressive ratio2.53.97.41.0-0.2-2.60.92.6-2.7-2.5-2.62.01.91.71.11.5
Food seeking constrained by brief footshock0.00.00.20.40.1-0.1-0.3-0.10.00.1-0.1-0.1-0.10.0-0.0-0.3
Seeking ratio, punishment vs. effort1.92.76.0-1.2-0.52.4-0.2-2.52.32.32.2-1.4-1.0-0.8-1.3-1.1
Retroperitoneal fat weight3.113.045.7-6.8-6.04.44.9-2.72.62.51.82.22.72.5-1.10.1
Reaction time number correct0.30.61.30.71.00.3-1.1-0.7-0.0-0.30.0-1.1-1.1-1.10.9-0.4
Reaction time mean minus median0.82.04.62.12.0-2.1-1.51.9-1.5-1.7-1.1-0.1-0.6-0.80.60.4
Reaction time mean minus median AUC0.41.03.01.61.7-1.1-1.50.8-0.6-0.8-0.5-0.6-1.0-1.10.3-0.3
Reaction time num false alarms0.30.51.6-0.4-0.70.80.5-1.31.11.00.3-0.1-0.10.4-0.4-0.6
Reaction time num false alarms AUC0.10.20.90.2-0.20.30.1-0.90.80.70.1-0.2-0.20.3-0.3-0.6
Reaction time trials correct on left0.30.61.30.71.00.3-1.1-0.7-0.0-0.30.0-1.1-1.1-1.10.9-0.4
Reaction time trials on left0.40.71.50.81.10.2-1.2-0.7-0.0-0.40.0-1.2-1.2-1.20.9-0.4
Reaction time mean0.10.20.60.00.4-0.4-0.20.8-0.2-0.30.40.3-0.1-0.2-0.80.3
Reaction time mean AUC0.10.21.0-0.10.2-0.5-0.01.0-0.4-0.50.30.50.10.0-0.80.6
Median of all reaction times0.10.20.9-0.6-0.3-0.00.40.6-0.0-0.10.50.60.30.2-1.00.4
Reaction time omissions0.71.03.01.71.5-1.3-1.11.0-1.1-1.2-0.5-0.2-0.6-0.60.00.4
Reaction time false alarm rate0.30.40.8-0.5-0.90.40.8-0.70.80.90.00.40.30.8-0.5-0.5
Reaction time premature initiation rate0.71.03.61.91.6-0.8-1.6-0.4-0.2-0.0-0.6-1.2-0.8-0.60.0-0.9
Reaction time premature initiations1.32.36.42.52.5-0.7-2.4-0.7-0.1-0.0-0.3-2.0-1.7-1.50.1-1.2
Std. dev. reaction times0.30.61.51.01.2-1.1-1.01.2-0.8-0.9-0.2-0.1-0.4-0.6-0.30.3
Reaction time trials completed0.40.71.50.81.10.2-1.2-0.7-0.0-0.40.0-1.2-1.2-1.20.9-0.4
Reaction time trials AUC0.30.51.20.60.90.3-1.0-0.80.0-0.30.0-1.1-1.0-1.00.8-0.4
Run reversals in cocaine runway, females1.61.62.90.6-0.7-1.51.11.2-1.4-1.4-1.71.31.31.70.81.1
Run reversals in cocaine runway, males1.71.73.2-0.50.31.6-0.8-1.81.81.61.1-1.4-1.5-1.40.4-1.5
Latency to leave start box in cocaine runway0.91.02.1-0.2-0.9-0.91.21.1-0.9-0.8-1.11.41.11.30.50.9
Latency to leave start box in cocaine runway, F0.50.61.2-0.1-0.6-0.61.10.9-0.6-0.4-0.31.11.01.1-0.40.9
Latency to leave start box in cocaine runway, M0.60.52.80.2-0.3-0.60.20.4-0.6-0.7-1.40.60.20.41.7-0.1
Std. dev. time between licks in bursts0.30.51.9-0.2-0.10.7-0.2-1.40.90.90.2-0.6-0.4-0.1-0.1-1.1
Total sessions with >9 infusions0.81.01.80.2-0.7-0.90.90.9-1.2-1.1-1.31.11.11.01.30.9
Short access day 1 total inactive lever presses0.70.93.1-1.6-1.81.01.5-0.40.40.40.30.90.90.9-0.50.3
Short access day 10 total inactive lever presses0.20.52.7-0.8-0.80.70.7-0.50.50.50.70.30.30.5-1.60.2
Short access day 1 total infusions1.21.64.0-1.3-1.9-0.02.00.4-0.6-0.6-0.91.71.61.50.61.1
Short access day 10 total infusions2.63.35.8-0.2-1.8-1.42.11.8-2.0-1.7-1.92.42.22.11.21.9
Short access total infusions1.41.82.9-0.4-1.5-0.81.70.9-1.3-1.1-1.71.71.61.61.21.0
Short access day 1 locomotion0.81.02.7-1.2-1.70.31.60.1-0.5-0.4-0.21.31.11.10.21.3
Short access day 10 total locomotion0.61.12.7-1.1-1.5-0.21.60.8-0.7-0.7-0.51.51.21.10.21.2
Short access total locomotion1.01.23.0-1.2-1.60.01.70.6-0.7-0.6-0.41.51.31.20.41.3
One hour access (0.3 mA shock)2.12.48.8-3.0-2.52.02.1-1.21.11.11.00.81.10.7-0.50.0
Compulsive drug intake1.11.32.51.31.5-0.0-1.6-0.90.81.10.6-1.6-1.1-0.7-0.6-1.6
One hour access (shock baseline)1.52.38.8-3.0-2.61.72.4-0.50.50.30.81.41.20.7-0.20.9
Social response proportion0.30.30.80.80.8-0.7-0.90.6-0.8-0.7-0.1-0.2-0.2-0.40.10.1
Social responses0.20.30.90.50.70.1-1.0-0.40.10.20.2-0.7-0.6-0.7-0.3-0.7
Social time0.40.51.20.50.90.1-1.1-0.50.30.40.2-1.0-0.7-0.8-0.4-1.0
Soleus weight1.44.115.3-3.9-3.12.72.5-1.51.91.71.40.91.11.1-0.7-0.3
Bone: stiffness1.93.16.72.11.2-2.6-0.72.4-2.5-2.4-2.10.80.40.21.81.2
Tibialis anterior weight4.113.940.76.46.0-3.6-5.11.4-1.7-2.3-2.5-3.0-3.6-3.53.3-1.8
Time to tail flick, vehicle, before self-admin0.70.71.90.4-0.0-0.90.30.9-1.3-1.4-1.00.60.70.50.71.0
Time to tail flick, vehicle, after self-admin1.62.15.60.5-0.5-1.91.11.7-1.7-1.4-2.41.51.61.71.10.6
Time to tail flick, test, before self-admin2.12.15.3-1.7-2.3-0.12.30.5-0.6-0.4-0.81.91.92.1-0.21.2
Time to tail flick, test, after self-admin0.10.10.40.10.50.0-0.5-0.0-0.3-0.5-0.1-0.3-0.4-0.60.40.4
Delta time to tail flick, vehicle, before/after SA0.40.41.40.4-0.1-1.00.30.8-0.7-0.5-1.20.50.60.80.4-0.0
Delta time to tail flick, test, before/after SA3.53.68.91.42.70.7-2.8-1.11.10.71.5-2.6-2.7-3.0-0.1-1.3
Tibia length0.92.46.21.92.3-0.9-2.10.7-0.7-1.2-0.4-1.1-1.7-2.12.5-0.3
Ambulatory time before self-admin0.50.82.30.70.4-1.2-0.11.5-1.2-1.2-0.80.70.30.10.80.8
Ambulatory time after self-admin0.30.31.3-0.4-0.5-0.10.50.7-0.3-0.20.30.80.50.5-0.61.1
Bone: tissue strength0.00.00.20.0-0.1-0.30.10.4-0.2-0.1-0.10.30.20.2-0.00.2
Total heroin consumption1.92.26.72.62.3-1.9-1.91.3-1.5-1.5-0.9-0.7-0.9-0.90.40.2
Bone: trabecular number1.32.25.01.20.2-2.00.22.1-2.2-2.0-1.71.21.00.81.41.3
Bone: trabecular spacing0.50.72.0-0.9-0.61.00.4-1.01.11.20.8-0.20.00.2-1.4-0.6
Bone: trabecular thickness0.60.71.4-0.5-1.1-0.31.10.8-0.8-0.6-0.51.21.11.10.20.9
Bone: trabecular tissue density1.52.27.2-2.7-1.72.31.3-1.41.81.51.70.1-0.00.0-0.7-0.3
Water consumed over 24 hours0.40.61.61.21.2-0.3-1.0-0.10.10.50.6-0.9-0.5-0.6-1.2-0.3
Number of responses in last shaping day0.20.20.5-0.00.10.5-0.2-0.60.60.70.3-0.5-0.3-0.2-0.6-0.5