Hub : Genes

LOC120097103

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Brain	gene expression	LOC120097103	0.09	0.05	5.7e-12	0.13	0.12	0.11	0.11	8.7e-12	4.5e-11	1.1e-10	1.2e-10
2	Adipose	gene expression	LOC120097103	0.03	0.02	1.3e-03	0.02	0.02	0.01	0.01	2.5e-03	6.5e-03	1.7e-02	1.1e-02
3	Eye	gene expression	LOC120097103	0.22	0.13	8.3e-03	0.09	0.13	0.05	0.08	1.5e-02	4.4e-03	5.6e-02	2.3e-02
4	NAcc	gene expression	LOC120097103	0.03	0.02	1.8e-03	0	0	-0	0	1.2e-01	1.7e-01	5.2e-01	2.5e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	0.5	0.9	1.2	-1.0	-1.0	0.6	-1.1
Area under the delay curve	3.7	3.9	7.4	2.7	2.4	-1.1	1.1
BMI with tail	1.0	3.1	4.9	2.2	2.2	-1.2	1.2
BMI without tail	0.2	0.5	0.9	-0.5	-0.5	1.0	-0.6
Body weight	1.4	5.9	9.5	3.1	2.6	-2.5	1.0
Weight adjusted by age	2.0	2.3	4.7	1.2	1.1	-2.2	1.3
Bone surface	0.2	0.3	0.5	-0.6	-0.7	0.3	-0.6
Bone volume	0.1	0.2	0.2	-0.3	-0.4	0.4	-0.5
Breakpoint value in progressive ratio session	0.4	0.4	0.6	0.7	0.8	0.2	-0.7
Number of licking bursts	0.3	0.3	0.6	0.8	0.7	-0.0	-0.2
Context. condit. distance diff. score	2.0	2.4	5.4	-1.2	-1.2	2.3	-1.1
Locomotion velocity, session 1	0.1	0.1	0.2	0.3	0.4	-0.1	-0.4
Locomotion distance, session 1	0.0	0.0	0.0	-0.1	-0.1	-0.0	0.0
Locomotion velocity, session 2	0.1	0.1	0.2	0.5	0.5	-0.1	-0.4
Locomotion distance, session 2	0.1	0.1	0.3	-0.4	-0.4	0.1	-0.5
Locomotion velocity, session 3	0.8	1.0	1.5	0.9	1.0	-1.2	0.8
Locomotion distance, session 3	0.4	0.5	0.7	0.9	0.9	-0.5	0.2
Stereotopy head waving bouts, day 3	0.2	0.2	0.3	-0.4	-0.4	-0.6	0.3
Stereotopy head waving duration, day 3	1.2	1.5	2.5	0.8	0.8	-1.6	1.4
Locomotion velocity, session 7	2.7	2.9	5.1	-1.2	-1.2	2.3	-1.9
Locomotion distance, session 7	3.9	4.9	7.1	-1.8	-1.8	2.7	-2.4
Stereotopy head waving bouts, day 7	1.7	1.9	2.6	1.5	1.4	-1.6	1.0
Stereotopy head waving duration, day 7	3.1	3.8	5.5	1.9	1.8	-2.4	1.7
Locomotion velocity, session 8	0.0	0.1	0.2	-0.0	0.2	0.4	0.1
Locomotion distance, session 8	0.8	1.1	2.2	-0.8	-0.8	1.5	-1.0
Degree of sensitization distance	8.0	8.0	11.0	-2.7	-2.7	3.3	-2.6
Degree of sensitization stereotypy	1.5	1.6	2.1	1.5	1.4	-1.3	0.9
Conditioned locomotion	0.4	0.5	0.9	-0.6	-0.8	0.9	-0.5
Cocaine response after cond. corrected	0.2	0.2	0.9	0.1	-0.1	1.0	0.0
Cocaine response after cond. not corrected	0.2	0.2	0.6	0.3	0.1	0.8	-0.3
Cocaine response before conditioning	0.3	0.4	0.6	0.4	0.4	-0.8	-0.7
Saline control response	0.0	0.0	0.1	-0.1	0.1	-0.2	-0.1
Bone: connectivity density	1.9	2.9	4.1	-1.8	-1.9	0.8	-2.0
Bone: cortical apparent density	0.1	0.1	0.2	0.4	0.4	0.0	0.0
Bone: cortical area	0.9	1.3	2.1	1.5	1.4	-0.2	1.1
Bone: cortical porosity	2.4	2.6	3.1	1.8	1.7	-1.7	1.2
Bone: cortical porosity	1.9	2.1	2.4	1.5	1.4	-1.5	1.3
Bone: cortical thickness	1.6	2.6	4.2	2.0	2.0	-0.7	1.3
Bone: cortical thickness	0.8	0.9	1.7	1.2	1.3	0.8	0.1
Bone: cortical tissue density	0.0	0.1	0.2	0.3	0.4	0.0	0.1
Condit. Reinf. active minus inactive responses	0.4	0.4	0.6	0.6	0.5	-0.8	0.7
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.5	-0.1	-0.2	-0.3	0.7
Condit. Reinf. active responses	0.3	0.4	0.6	0.7	0.7	-0.7	0.2
Condit. Reinf. inactive responses	0.4	0.4	1.3	0.3	0.4	-0.4	-1.1
Incentive salience index mean	1.6	1.9	2.4	1.5	1.4	-1.5	1.0
Condit. Reinf. lever presses	1.8	2.4	3.4	1.9	1.8	-1.6	0.5
Condit. Reinf. active minus inactive responses	0.2	0.2	0.4	-0.5	-0.4	0.6	-0.4
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.1	-0.2	-0.2	0.3	0.2
Condit. Reinf. active responses	0.3	0.5	0.6	-0.7	-0.5	0.8	-0.7
Condit. Reinf. inactive responses	1.5	1.8	2.8	-1.3	-1.1	1.2	-1.7
Condit. Reinf. lever presses	0.1	0.1	0.5	-0.0	0.0	-0.7	0.2
Condit. Reinf. lever reinforcers received	0.1	0.1	0.2	-0.4	-0.2	0.4	-0.4
Conditioned reinforcement - actives	6.8	6.8	8.7	-2.9	-2.9	2.8	-1.4
Conditioned reinforcement - inactives	2.3	2.6	4.1	-1.7	-1.4	1.2	-2.0
Conditioned locomotion	2.0	2.4	4.2	-1.4	-1.3	2.1	-1.3
Patch foraging indifference point 0 sec	0.2	0.3	0.8	0.2	0.1	-0.7	-0.9
Patch foraging indifference point AUC	0.5	0.6	1.7	-0.2	0.1	0.8	1.3
Delay disc. indifference point, 0s delay	0.3	0.3	1.2	0.3	-0.1	0.3	-1.1
Delay disc. indifference point, 16s delay	2.5	2.5	4.3	1.9	2.1	-0.7	1.2
Delay disc. indifference point, 2s delay	0.5	0.5	1.2	1.1	0.6	-0.4	0.5
Delay disc. indifference point, 24s delay	2.3	2.2	4.6	2.1	2.0	-0.4	0.6
Delay disc. indifference point, 4s delay	3.1	3.3	4.7	2.2	2.1	-1.4	1.5
Delay disc. indifference point, 8s delay	5.0	5.2	9.3	3.0	2.6	-1.6	1.4
Indifference point function ln k	0.5	0.7	1.5	0.8	0.7	-1.2	-0.2
Indifference point function log k	0.5	0.7	1.5	0.8	0.7	-1.2	-0.2
Patch foraging total patch changes 0 sec	0.3	0.4	0.9	0.5	0.4	-0.9	-0.6
Patch foraging total patch changes 12 sec	0.1	0.1	0.2	0.4	0.4	-0.1	-0.1
Patch foraging total patch changes 18 sec	0.3	0.4	0.7	-0.6	-0.5	0.8	-0.3
Patch foraging total patch changes 24 sec	0.1	0.2	0.3	0.3	0.3	-0.4	0.6
Patch foraging total patch changes 6 sec	0.0	0.0	0.1	0.1	0.2	-0.0	-0.1
Patch foraging time to switch 0 sec	0.4	0.6	1.8	-0.2	-0.5	0.5	-1.3
Patch foraging water rate 0 sec	0.8	1.3	1.9	0.9	1.4	-1.2	1.1
Patch foraging water rate 12 sec	0.3	0.5	0.8	0.2	0.7	-0.9	0.9
Patch foraging water rate 18 sec	4.2	5.7	6.4	2.5	2.3	-2.3	2.4
Patch foraging water rate 24 sec	0.1	0.2	0.8	-0.0	0.1	0.1	0.9
Patch foraging water rate 6 sec	1.4	2.0	3.8	0.8	1.2	-1.5	2.0
Seeking ratio, delayed vs. immediate footshock	0.4	0.5	1.9	-0.2	-0.2	-0.0	-1.4
Distance traveled before self-admin	0.2	0.2	0.6	-0.5	-0.3	-0.0	0.8
Distance traveled after self-admin	0.1	0.2	0.6	-0.3	-0.2	0.1	0.7
Extensor digitorum longus weight	8.1	31.9	41.0	5.6	5.5	-4.9	6.4
Bone: elastic displacement	0.1	0.1	0.1	-0.4	-0.3	-0.0	-0.4
Bone: elastic work	0.5	0.6	1.0	0.9	0.7	-1.0	0.5
Bone: endosteal estimation	0.0	0.1	0.2	-0.3	-0.4	0.2	0.1
Bone: endosteal perimeter	0.3	0.6	1.1	-0.9	-1.1	0.6	-0.3
Epididymis fat weight	0.2	0.6	2.0	0.2	0.0	0.5	-1.4
Delta time in closed arm before/after self-admin	0.6	0.6	0.9	-1.0	-0.7	0.4	-0.7
Delta time in open arm before/after self-admin	0.1	0.1	0.1	-0.0	-0.2	0.3	-0.3
Diff in mean of infusions in LGA sessions	4.3	4.7	6.7	2.6	2.3	-2.5	0.8
Delay discount exponential model param	4.3	4.5	8.2	-2.9	-2.5	1.3	-1.4
Extinction: sum of active levers before priming	0.6	0.6	1.7	-0.5	-0.3	0.8	-1.3
Active lever presses in extinction session 6	0.7	0.7	0.9	-0.8	-0.5	0.9	-0.9
Bone: final force	0.9	1.4	2.3	1.5	1.4	-0.6	1.0
Bone: final moment	0.9	1.5	2.2	1.5	1.4	-0.9	1.1
Food consumed during 24 hour testing period	0.2	0.2	0.6	-0.0	0.0	-0.5	0.7
Glucose	0.1	0.2	0.3	0.5	0.3	0.4	0.3
Heart weight	0.1	0.1	0.2	0.1	-0.0	-0.4	0.4
Delay discount hyperbolic model param	4.5	4.8	8.4	-2.9	-2.5	1.4	-1.6
Intermittent access intake day 1-15 change	0.6	0.6	1.2	-0.7	-1.1	0.7	-0.4
Intermittent access intake escalation	0.6	0.6	1.2	-0.7	-1.1	0.7	-0.1
Intermittent access intake escalation 2	0.3	0.3	0.6	-0.5	-0.8	0.3	-0.1
Intermitt. access day 1 inactive lever presses	1.2	1.3	2.6	-1.0	-1.0	0.7	-1.6
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.8	-0.1	-0.1	-0.9	0.3
Intermitt. access escalation Index	0.7	0.6	1.5	-0.4	-0.8	1.2	-0.2
Intermittent access day 1 total infusions	0.4	0.5	1.2	-0.5	-0.6	1.1	0.4
Intermittent access day 15 total infusions	1.5	1.7	2.9	-1.2	-1.6	1.7	-0.1
Intermittent access terminal intake (last 3 days)	1.3	1.4	2.1	-1.0	-1.4	1.4	0.7
Intermittent access total infusions	1.7	1.9	3.9	-1.3	-1.4	2.0	-0.2
Intermittent access day 1 locomotion	0.1	0.1	0.1	0.3	0.3	0.3	-0.1
Intermittent access day 15 total locomotion	0.3	0.3	0.6	-0.5	-0.6	0.8	-0.2
Intermittent access total locomotion	0.1	0.1	0.2	0.1	-0.1	0.5	-0.2
Intermittent access standard deviation	0.8	0.9	1.2	-1.0	-1.1	0.5	1.0
Left kidney weight	1.3	3.8	6.0	1.9	1.6	-2.5	1.8
Right kidney weight	1.5	4.2	8.3	2.1	1.9	-2.9	0.5
Cocaine induced anxiety	0.4	0.5	0.8	0.4	0.5	-0.9	0.9
Post-drug Anxiety	0.4	0.4	1.2	0.3	0.5	-1.1	-0.4
Baseline Anxiety	0.6	0.6	2.3	-0.2	-0.1	0.3	-1.5
Tail length	0.5	1.4	2.1	-1.2	-1.4	0.6	-1.3
Length with tail	0.3	1.1	2.8	1.1	0.7	-1.7	-0.2
Length without tail	3.5	7.7	10.1	3.1	2.7	-3.2	1.9
Times rat made contact with spout	0.1	0.1	0.2	-0.2	-0.3	0.4	0.1
Lifetime Intake	2.0	2.3	4.0	-1.5	-1.7	2.0	-0.3
Liver weight, left	3.1	4.9	6.0	2.3	1.9	-2.1	2.5
Liver weight, right	1.8	3.0	4.4	1.8	1.7	-1.4	2.1
Locomotor activity	3.1	4.9	8.1	2.3	2.0	-2.8	1.5
Locomotor testing distance	0.3	0.5	1.5	0.4	0.2	-1.2	-0.4
Locomotor testing rearing	0.6	0.9	1.7	-0.6	-0.7	-1.0	-1.3
Locomotion in novel chamber	0.6	0.7	1.1	1.1	1.0	-0.8	0.3
Locomotion in novel chamber post-restriction	0.4	0.5	1.5	0.5	0.5	-0.1	1.2
Fecal boli incidents, locomotor time 1	0.7	0.8	2.4	0.8	0.0	-0.3	1.5
Change in fecal boli incidents, locomotor task	0.2	0.2	0.6	-0.3	0.0	-0.3	-0.8
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.5	-0.1	-0.1	-0.7	-0.4
Bouts of movement, locomotor time 1	0.1	0.1	0.4	-0.1	-0.3	0.2	0.6
Total resting periods, locomotor time 1	0.2	0.3	0.5	-0.3	-0.4	0.7	0.5
Rest time, locomotor task time 1	0.1	0.1	0.2	0.1	0.2	0.5	0.1
Distance moved, locomotor task time 1	0.2	0.2	0.3	-0.5	-0.5	0.1	-0.5
Vertical activity count, locomotor time 1	0.4	0.4	0.8	0.2	0.3	-0.9	0.7
Time >=10cm from walls, locomotor time 2	0.1	0.1	0.3	-0.5	-0.3	-0.5	0.1
Bouts of movement, locomotor time 2	1.3	1.4	2.3	1.5	1.3	-0.6	1.1
Total resting periods, locomotor time 2	1.8	2.0	3.1	1.8	1.5	-0.7	1.4
Rest time, locomotor task time 2	1.8	2.0	4.4	1.4	1.3	-0.2	2.1
Distance moved, locomotor task time 2	0.8	0.9	1.6	-1.1	-0.8	0.3	-1.3
Vertical activity count, locomotor time 2	0.1	0.1	0.2	-0.5	-0.2	-0.2	-0.4
Light reinforcement 1	0.3	0.5	1.4	-0.3	-0.3	0.7	-1.2
Light reinforcement 2	0.5	0.6	1.2	-0.7	-0.8	1.1	-0.6
Bone: marrow area	0.1	0.1	0.3	-0.4	-0.5	0.3	-0.0
Bone: maximum diameter	0.4	0.7	1.5	0.8	0.7	0.1	1.2
Bone: maximum force	1.2	2.0	3.2	1.8	1.6	-0.7	1.3
Bone: maximum moment	1.2	2.1	3.0	1.7	1.5	-0.9	1.4
Mean time between licks in bursts	3.7	5.2	6.6	-2.6	-2.5	1.5	-2.4
Mean num. licks in bursts	0.4	0.5	0.9	-0.9	-0.9	0.4	0.3
Cd content in liver	0.3	0.3	0.5	-0.7	-0.7	0.1	-0.3
Co content in liver	0.8	0.9	1.8	0.9	0.9	0.0	1.3
Cu content in liver	0.4	0.4	0.8	0.5	0.6	-0.7	0.9
Fe content in liver	0.9	1.1	2.0	-1.0	-1.1	0.4	-1.4
K content in liver	0.6	0.6	0.9	-0.5	-0.5	1.0	-1.0
Mg content in liver	0.9	1.0	1.3	-1.0	-1.0	1.1	-0.8
Mn content in liver	2.0	2.2	3.6	-1.2	-1.2	1.6	-1.9
Na content in liver	6.2	6.5	9.3	2.6	2.6	-3.0	1.9
Rb content in liver	0.9	1.1	1.7	-1.3	-1.3	0.8	-0.8
Se content in liver	0.4	0.4	1.5	-0.2	-0.1	-0.4	-1.2
Sr content in liver	1.7	1.6	2.2	-1.5	-1.5	0.7	-1.2
Zn content in liver	1.8	2.0	3.8	1.2	1.2	-1.9	1.2
Bone: minimum diameter	0.4	0.7	1.3	0.9	0.8	-0.3	1.1
Time in familiar zone, hab. session 1	0.5	0.4	1.0	-0.4	-0.4	1.0	-0.6
Time in novel zone, hab. session 1	1.6	1.6	1.7	1.3	1.3	-1.3	1.2
Total zone transitions, hab. session 1	0.3	0.4	0.6	0.8	0.8	-0.2	0.4
Total locomotion distance, hab. session 1	0.1	0.1	0.2	0.2	0.2	0.3	-0.5
Locomotion velocity, hab. session 1	0.1	0.1	0.3	0.2	0.2	0.0	-0.5
Time in familiar zone, hab. session 2	0.2	0.2	0.3	-0.4	-0.4	0.6	-0.1
Time in novel zone, hab. session 2	0.0	0.0	0.1	0.1	0.2	-0.1	0.1
Total zone transitions, hab. session 2	0.4	0.5	0.6	0.6	0.7	-0.8	0.7
Total locomotion distance, hab. session 2	0.0	0.1	0.1	0.3	0.4	-0.1	0.2
Locomotion velocity, hab. session 2	0.2	0.3	0.5	0.6	0.7	-0.4	0.5
Novel to familiar place preference ratio	0.3	0.3	0.6	-0.5	-0.5	0.8	-0.5
Novelty place preference	0.3	0.3	0.4	-0.5	-0.5	0.7	-0.6
Time in novel zone, NPP test	0.2	0.2	0.2	-0.3	-0.4	0.5	-0.4
Total zone transitions, NPP test	0.0	0.0	0.2	-0.0	0.0	0.1	-0.4
Total locomotion distance, NPP test	1.7	2.3	3.9	-1.4	-1.4	1.3	-2.0
Locomotion velocity, NPP test	1.7	2.4	3.7	-1.4	-1.4	1.4	-1.9
Intraocular pressure	1.9	2.7	3.9	-2.0	-2.0	1.3	-1.2
Delta distance traveled before/after self-admin	0.2	0.2	0.3	0.5	0.4	-0.3	0.4
Delta ambulatory time before/after self-admin	0.1	0.1	0.2	0.3	0.2	-0.0	0.4
Parametrial fat weight	3.7	7.2	9.2	-2.5	-2.4	3.0	-2.7
Pavlov. Cond. lever latency	0.6	0.8	1.2	-1.1	-1.0	0.9	-0.3
Pavlov. Cond. magazine entry latency	0.6	0.7	1.2	0.9	0.9	-1.1	0.3
Pavlov. Cond. change in total contacts	2.8	3.0	3.7	1.9	1.9	-1.7	1.5
Pavlov. Cond. index score	2.3	2.9	4.0	2.0	1.9	-1.9	0.7
Pavlov. Cond. latency score	1.6	2.0	2.9	1.7	1.6	-1.6	0.5
Pavlov. Cond. lever contacts	1.3	1.5	2.0	1.4	1.3	-1.4	0.5
Pavlov. Cond. magazine entry number	1.7	2.1	2.7	-1.6	-1.5	1.6	-0.9
Pavlov. Cond. intertrial magazine entries	0.0	0.0	0.1	0.0	0.0	-0.3	-0.3
Pavlov. Cond. lever-magazine prob. diff.	2.9	3.6	4.9	2.2	2.1	-2.1	0.9
Pavlov. Cond. response bias	2.5	3.0	3.7	1.9	1.8	-1.9	1.1
Pavlov. Cond. lever latency	1.6	2.2	4.0	-1.0	-1.1	2.0	-1.5
Pavlov. Cond. magazine entry latency	1.8	2.1	2.9	1.7	1.7	-1.5	0.6
Pavlov. Cond. change in total contacts	4.1	5.6	8.0	2.0	2.2	-2.8	2.4
Pavlov. Cond. index score	2.7	3.5	5.3	1.8	1.9	-2.3	1.5
Pavlov. Cond. latency score	2.5	3.1	5.2	1.6	1.7	-2.3	1.3
Pavlov. Cond. lever contacts	1.3	1.8	3.5	0.9	1.0	-1.9	1.4
Pavlov. Cond. magazine entry number	0.7	0.9	1.4	-1.2	-1.2	0.8	-0.2
Pavlov. Cond. intertrial magazine entries	9.5	12.4	14.6	-3.8	-3.8	3.2	-3.2
Pavlov. Cond. lever-magazine prob. diff.	2.7	3.4	5.0	1.8	1.9	-2.2	1.4
Pavlov. Cond. response bias	1.9	2.6	3.9	1.5	1.6	-2.0	1.4
Time in closed arm before self-admin	2.6	3.0	3.7	1.8	1.8	-1.9	1.2
Time in closed arm after self-admin	0.5	0.6	1.0	0.6	0.9	-1.0	0.0
Time in open arm before self-admin	0.8	0.9	1.4	-1.2	-1.1	1.0	-0.1
Time in open arm after self-admin	0.5	0.6	1.0	-0.7	-1.0	0.7	-0.5
Bone: periosteal estimation	0.1	0.2	0.4	0.5	0.3	0.2	0.6
Bone: periosteal perimeter	0.0	0.0	0.1	0.0	0.1	0.3	0.1
Bone: post-yield work	0.7	0.9	3.0	0.2	0.2	1.7	0.7
Progressive ratio test 1 active lever presses	0.5	0.6	1.6	-0.3	-0.4	1.2	0.7
Progressive ratio test 1 breakpoint	0.5	0.6	1.7	-0.2	-0.3	1.3	0.7
Progressive ratio test 1 inactive lever presses	0.9	1.0	1.3	-1.0	-1.1	1.0	-0.8
Progressive ratio test 2 active lever presses	2.5	2.7	4.1	-1.7	-2.0	2.0	-0.2
Progressive ratio test 2 breakpoint	1.8	2.0	3.3	-1.4	-1.8	1.6	-0.1
Progressive ratio test 2 inactive lever presses	1.6	1.8	2.7	-1.6	-1.6	1.3	-0.5
Incentive Sensitization - Responses	2.0	2.0	4.1	-1.7	-2.0	0.9	-0.7
Incentive Sensitization - Breakpoint	2.1	2.1	4.3	-1.7	-2.1	0.9	-0.7
Sum of active levers in priming session hrs 5-6	0.8	0.8	1.3	-0.9	-0.6	1.2	-0.8
Progressive ratio	1.2	1.4	2.4	1.1	0.9	-1.5	1.0
Food seeking constrained by brief footshock	0.2	0.3	0.5	-0.6	-0.1	0.7	-0.5
Seeking ratio, punishment vs. effort	0.5	0.6	1.3	-0.8	-0.4	1.2	-0.6
Retroperitoneal fat weight	0.6	2.0	3.6	-0.8	-1.4	1.9	-1.4
Reaction time number correct	0.3	0.5	1.0	-0.7	-1.0	0.6	-0.3
Reaction time mean minus median	0.7	0.9	1.7	0.9	0.9	-1.3	0.4
Reaction time mean minus median AUC	0.3	0.4	1.0	0.5	0.5	-1.0	-0.1
Reaction time num false alarms	0.6	0.8	1.3	1.2	0.8	-1.0	-0.2
Reaction time num false alarms AUC	0.6	0.8	1.5	1.2	0.8	-1.0	0.2
Reaction time trials correct on left	0.3	0.5	1.0	-0.7	-1.0	0.6	-0.3
Reaction time trials on left	0.4	0.6	1.2	-0.8	-1.1	0.6	-0.4
Reaction time mean	0.2	0.2	0.5	-0.3	-0.1	-0.7	0.6
Reaction time mean AUC	0.3	0.4	1.1	-0.0	0.1	-1.1	0.7
Median of all reaction times	0.2	0.2	0.5	-0.7	-0.4	-0.4	0.4
Reaction time omissions	2.0	2.7	3.8	-1.8	-2.0	1.0	-1.7
Reaction time false alarm rate	0.9	1.2	2.1	1.4	1.2	-1.1	0.2
Reaction time premature initiation rate	0.3	0.4	0.7	0.6	0.9	-0.5	0.6
Reaction time premature initiations	0.0	0.1	0.2	0.1	0.2	-0.1	0.4
Std. dev. reaction times	0.1	0.1	0.4	0.0	0.2	-0.6	0.4
Reaction time trials completed	0.4	0.6	1.2	-0.8	-1.1	0.6	-0.4
Reaction time trials AUC	0.5	0.7	1.4	-0.9	-1.2	0.7	-0.4
Run reversals in cocaine runway, females	0.5	0.4	1.2	-1.1	-0.0	0.5	-0.6
Run reversals in cocaine runway, males	3.9	3.8	6.6	1.7	1.9	-1.5	2.6
Latency to leave start box in cocaine runway	0.9	1.0	1.9	-1.2	-1.4	0.7	0.5
Latency to leave start box in cocaine runway, F	0.3	0.4	1.0	-0.4	-0.5	-0.1	1.0
Latency to leave start box in cocaine runway, M	1.2	1.1	2.1	-1.3	-1.5	0.7	-0.6
Std. dev. time between licks in bursts	1.9	2.3	4.2	-1.5	-1.5	0.7	-2.1
Total sessions with >9 infusions	1.3	1.4	2.4	-0.9	-1.5	1.2	-1.0
Short access day 1 total inactive lever presses	0.7	0.7	1.0	-0.7	-0.8	1.0	0.9
Short access day 10 total inactive lever presses	0.9	1.0	1.6	-0.9	-0.8	0.9	-1.3
Short access day 1 total infusions	2.9	3.1	5.0	-1.8	-2.2	2.0	-0.4
Short access day 10 total infusions	0.2	0.2	0.5	-0.0	0.0	0.7	0.6
Short access total infusions	0.6	0.7	1.2	-0.7	-1.1	1.1	0.0
Short access day 1 locomotion	0.1	0.1	0.2	-0.2	-0.5	-0.1	-0.0
Short access day 10 total locomotion	0.5	0.5	0.8	0.9	0.7	-0.7	-0.6
Short access total locomotion	0.2	0.2	0.3	0.5	0.3	-0.5	-0.6
One hour access (0.3 mA shock)	0.9	1.0	2.6	-0.7	-1.0	1.6	-0.0
Compulsive drug intake	0.4	0.4	1.1	0.3	0.4	0.4	-1.0
One hour access (shock baseline)	1.3	1.5	2.2	-1.1	-1.5	1.5	0.6
Social response proportion	2.5	2.7	4.0	-1.8	-2.0	1.6	-1.0
Social responses	3.8	4.9	6.2	-2.1	-2.2	2.0	-2.5
Social time	0.2	0.2	0.5	-0.5	-0.4	-0.7	-0.2
Soleus weight	0.3	0.9	1.4	1.2	1.1	-0.4	1.0
Bone: stiffness	0.8	1.2	2.0	1.4	1.3	-0.7	0.9
Tibialis anterior weight	7.8	26.7	28.4	5.2	5.3	-4.8	5.3
Time to tail flick, vehicle, before self-admin	1.7	1.7	3.5	1.3	1.9	-1.3	0.1
Time to tail flick, vehicle, after self-admin	1.9	2.1	3.0	1.2	1.6	-1.1	1.7
Time to tail flick, test, before self-admin	0.2	0.2	0.4	0.2	0.3	-0.6	0.6
Time to tail flick, test, after self-admin	4.6	4.8	6.2	-2.5	-2.3	2.0	-1.9
Delta time to tail flick, vehicle, before/after SA	0.6	0.6	1.0	-0.7	-0.8	0.6	1.0
Delta time to tail flick, test, before/after SA	4.9	4.4	5.5	-2.3	-2.0	2.1	-1.9
Tibia length	0.8	2.4	5.9	1.4	1.3	-2.4	-0.3
Ambulatory time before self-admin	0.1	0.1	0.2	-0.3	-0.0	0.1	0.4
Ambulatory time after self-admin	0.5	0.5	1.4	0.5	0.6	-0.5	1.2
Bone: tissue strength	0.2	0.2	0.5	-0.5	-0.7	0.1	0.1
Total heroin consumption	0.7	0.8	1.4	0.8	0.7	-0.7	1.2
Bone: trabecular number	1.0	1.6	2.2	-1.2	-1.3	0.9	-1.5
Bone: trabecular spacing	1.9	2.5	3.6	1.9	1.9	-1.1	1.3
Bone: trabecular thickness	0.2	0.3	0.5	0.7	0.7	-0.4	0.1
Bone: trabecular tissue density	2.0	2.9	4.0	1.9	2.0	-1.6	1.2
Water consumed over 24 hours	1.3	1.5	2.1	1.2	1.1	-1.2	1.5
Number of responses in last shaping day	0.2	0.2	0.3	0.5	-0.0	-0.5	0.5