Hub : Genes

Gstp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Gstp1 0.15 0.1 1.7e-09 0.1 0.11 0.11 0.1 1.6e-08 4.3e-09 7.1e-09 8.8e-09
2 Liver mRNA stability Gstp1 0.15 0.08 1.2e-09 0.06 0.05 0.06 0.05 2.6e-07 1.1e-06 3.7e-07 1.5e-06
3 BLA gene expression Gstp1 0.22 0.17 6.5e-08 0.13 0.13 0.17 0.12 3.0e-07 3.0e-07 2.9e-09 5.9e-07
4 Brain gene expression Gstp1 0.32 0.15 0.0e+00 0.2 0.2 0.2 0.2 6.8e-19 2.4e-18 1.3e-18 7.1e-19
5 NAcc gene expression Gstp1 0.19 0.12 0.0e+00 0.13 0.17 0.17 0.17 8.0e-19 7.0e-25 2.1e-24 8.2e-25
6 PL gene expression Gstp1 0.08 0.05 1.3e-08 0.07 0.07 0.07 0.07 5.7e-08 2.4e-08 2.3e-08 3.4e-08
7 IC gene expression Gstp1 0.14 0.1 1.4e-04 0.04 0.06 0.06 0.04 5.8e-03 1.7e-03 2.3e-03 9.5e-03
8 OFC gene expression Gstp1 0.26 0.16 3.4e-04 0.1 -0.01 0.1 -0.01 2.2e-03 5.4e-01 2.3e-03 7.3e-01
9 Adipose gene expression Gstp1 0.08 0.05 2.5e-08 0.02 0.06 0.06 0.06 9.6e-04 3.8e-07 3.9e-07 7.9e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.71.35.60.3-0.7-1.40.7-0.3-0.9-0.5-1.3-2.4
Area under the delay curve0.30.41.5-0.20.0-0.20.0-0.5-0.7-0.6-0.9-1.2
BMI with tail0.62.16.01.7-2.2-0.22.10.90.00.6-0.5-2.4
BMI without tail0.61.94.21.9-2.00.41.91.40.91.20.6-0.9
Body weight1.88.014.13.5-3.72.23.73.02.52.81.9-0.4
Weight adjusted by age0.81.32.11.2-1.41.11.11.21.21.21.00.5
Bone surface1.11.94.41.6-2.1-0.02.11.00.30.7-0.4-2.1
Bone volume0.50.94.20.6-0.9-0.80.90.0-0.5-0.2-1.0-2.0
Breakpoint value in progressive ratio session1.61.93.51.7-1.91.11.71.61.31.41.00.0
Number of licking bursts0.00.10.10.0-0.10.30.3-0.0-0.1-0.1-0.3-0.4
Context. condit. distance diff. score1.01.21.5-1.21.2-1.2-1.0-1.2-1.2-1.2-1.1-0.6
Locomotion velocity, session 10.00.00.00.0-0.0-0.00.2-0.0-0.0-0.0-0.1-0.1
Locomotion distance, session 10.40.52.10.4-0.6-0.40.70.0-0.4-0.2-0.7-1.5
Locomotion velocity, session 21.92.23.11.7-1.81.41.71.61.51.51.20.3
Locomotion distance, session 20.40.61.41.0-1.20.41.10.70.50.60.1-0.7
Locomotion velocity, session 30.70.82.6-0.30.1-1.00.1-0.6-1.0-0.8-1.2-1.6
Locomotion distance, session 30.10.10.2-0.10.0-0.40.1-0.2-0.3-0.2-0.3-0.5
Stereotopy head waving bouts, day 31.11.32.3-0.80.6-1.3-0.7-1.0-1.3-1.1-1.4-1.5
Stereotopy head waving duration, day 31.51.82.3-1.21.1-1.4-1.1-1.4-1.5-1.4-1.5-1.2
Locomotion velocity, session 70.40.41.5-0.2-0.0-0.9-0.0-0.4-0.7-0.5-0.8-1.2
Locomotion distance, session 70.10.20.50.6-0.70.00.60.40.30.40.2-0.3
Stereotopy head waving bouts, day 71.01.12.3-0.70.5-1.3-0.5-1.0-1.3-1.1-1.3-1.5
Stereotopy head waving duration, day 70.30.41.90.3-0.5-0.40.6-0.0-0.4-0.2-0.6-1.4
Locomotion velocity, session 81.21.52.21.4-1.51.31.51.31.21.20.90.1
Locomotion distance, session 80.40.50.8-0.60.5-0.8-0.4-0.8-0.8-0.8-0.9-0.8
Degree of sensitization distance0.10.10.40.5-0.6-0.10.50.30.10.2-0.0-0.5
Degree of sensitization stereotypy0.10.10.70.2-0.3-0.30.3-0.1-0.3-0.1-0.3-0.9
Conditioned locomotion3.94.55.91.9-1.72.41.72.22.42.32.31.9
Cocaine response after cond. corrected0.10.20.3-0.40.4-0.5-0.4-0.4-0.4-0.4-0.3-0.3
Cocaine response after cond. not corrected0.30.30.6-0.40.3-0.8-0.3-0.6-0.7-0.6-0.6-0.7
Cocaine response before conditioning0.00.00.10.1-0.20.10.30.0-0.0-0.0-0.2-0.4
Saline control response2.43.24.72.1-2.21.92.21.91.71.81.30.2
Bone: connectivity density1.11.74.71.5-1.9-0.41.90.80.10.5-0.5-2.2
Bone: cortical apparent density0.60.81.00.8-0.70.90.70.91.01.01.00.8
Bone: cortical area0.91.42.71.0-0.91.61.01.21.31.21.21.0
Bone: cortical porosity0.00.00.10.1-0.10.30.10.0-0.00.0-0.1-0.2
Bone: cortical porosity0.30.30.60.6-0.60.80.60.50.50.50.40.0
Bone: cortical thickness6.510.815.43.1-2.93.92.93.43.63.53.42.6
Bone: cortical thickness2.42.83.41.7-1.61.81.61.81.81.81.71.1
Bone: cortical tissue density0.81.11.41.0-0.91.00.91.11.21.11.10.9
Condit. Reinf. active minus inactive responses0.10.10.50.1-0.3-0.40.3-0.0-0.2-0.1-0.3-0.7
Condit. Reinf. active-inactive response ratio0.20.20.4-0.20.2-0.6-0.1-0.4-0.5-0.4-0.5-0.6
Condit. Reinf. active responses0.00.00.1-0.0-0.0-0.20.1-0.1-0.1-0.1-0.1-0.3
Condit. Reinf. inactive responses0.00.00.1-0.30.3-0.1-0.3-0.2-0.1-0.20.00.2
Incentive salience index mean0.10.10.30.2-0.4-0.10.40.1-0.10.0-0.2-0.6
Condit. Reinf. lever presses0.00.10.20.2-0.20.40.30.20.30.20.20.2
Condit. Reinf. active minus inactive responses1.31.62.9-1.00.8-1.7-0.7-1.2-1.5-1.3-1.5-1.5
Condit. Reinf. active-inactive response ratio2.32.73.8-1.61.5-2.0-1.4-1.7-1.8-1.7-1.7-1.2
Condit. Reinf. active responses0.81.13.0-0.40.2-1.4-0.1-0.8-1.2-0.9-1.3-1.7
Condit. Reinf. inactive responses0.40.51.00.9-1.00.21.00.50.20.4-0.1-0.9
Condit. Reinf. lever presses0.30.41.30.7-0.9-0.10.90.3-0.10.2-0.4-1.1
Condit. Reinf. lever reinforcers received0.60.83.0-0.1-0.1-1.20.2-0.5-1.0-0.7-1.2-1.7
Conditioned reinforcement - actives0.10.20.9-0.30.40.6-0.5-0.10.20.00.51.0
Conditioned reinforcement - inactives2.43.64.7-2.22.0-1.9-2.1-2.1-2.0-2.0-1.6-0.7
Conditioned locomotion5.97.712.1-3.53.5-2.3-3.5-3.1-2.5-2.8-1.90.2
Patch foraging indifference point 0 sec0.30.60.9-0.70.9-1.0-0.8-0.7-0.8-0.7-0.5-0.3
Patch foraging indifference point AUC1.31.83.41.2-1.31.91.11.31.51.41.21.1
Delay disc. indifference point, 0s delay0.91.03.0-0.40.3-0.9-0.1-0.8-1.2-0.9-1.5-1.7
Delay disc. indifference point, 16s delay1.11.21.7-1.31.2-0.6-1.2-1.3-1.2-1.3-1.1-0.6
Delay disc. indifference point, 2s delay0.80.91.4-0.90.6-1.0-0.7-1.0-1.1-1.1-1.2-1.1
Delay disc. indifference point, 24s delay0.30.31.00.3-0.11.00.20.50.50.50.60.6
Delay disc. indifference point, 4s delay0.20.20.80.0-0.3-0.10.2-0.2-0.3-0.3-0.6-0.9
Delay disc. indifference point, 8s delay0.10.10.60.1-0.00.30.3-0.1-0.3-0.2-0.3-0.7
Indifference point function ln k2.84.97.2-2.52.7-2.5-2.7-2.3-2.1-2.2-1.5-0.3
Indifference point function log k2.84.97.2-2.52.7-2.5-2.7-2.3-2.1-2.2-1.5-0.3
Patch foraging total patch changes 0 sec0.10.10.3-0.30.6-0.4-0.4-0.2-0.2-0.20.10.3
Patch foraging total patch changes 12 sec2.02.63.71.9-1.91.71.71.71.61.71.30.4
Patch foraging total patch changes 18 sec0.10.20.50.5-0.70.50.60.40.30.40.1-0.2
Patch foraging total patch changes 24 sec0.71.11.41.1-1.01.20.91.11.21.21.10.8
Patch foraging total patch changes 6 sec0.30.51.11.0-0.90.31.10.70.30.60.1-0.6
Patch foraging time to switch 0 sec0.51.03.60.9-1.50.21.30.4-0.10.1-0.7-1.9
Patch foraging water rate 0 sec1.32.86.7-2.02.6-0.8-2.4-1.3-0.6-1.00.22.1
Patch foraging water rate 12 sec2.14.310.8-2.63.3-1.2-3.0-1.9-1.1-1.5-0.31.9
Patch foraging water rate 18 sec0.61.02.2-1.31.5-0.7-1.3-1.0-0.7-0.9-0.30.6
Patch foraging water rate 24 sec0.91.33.4-1.31.8-0.2-1.7-0.7-0.2-0.50.51.8
Patch foraging water rate 6 sec0.60.93.0-1.01.30.2-1.4-0.50.1-0.30.51.7
Seeking ratio, delayed vs. immediate footshock0.30.41.4-0.2-0.0-0.3-0.0-0.4-0.7-0.6-0.9-1.2
Distance traveled before self-admin0.10.10.60.0-0.2-0.40.1-0.2-0.2-0.2-0.4-0.8
Distance traveled after self-admin0.00.00.10.1-0.1-0.20.20.00.00.0-0.0-0.2
Extensor digitorum longus weight7.027.636.55.8-6.05.55.85.65.35.54.61.9
Bone: elastic displacement1.21.44.50.30.01.5-0.00.81.31.01.62.1
Bone: elastic work3.14.06.01.9-1.72.41.72.12.22.12.11.6
Bone: endosteal estimation2.14.65.9-2.01.8-2.3-1.9-2.3-2.4-2.3-2.4-1.8
Bone: endosteal perimeter4.59.512.2-2.92.7-3.4-2.7-3.2-3.5-3.3-3.4-2.6
Epididymis fat weight3.411.716.7-4.14.0-3.0-4.0-3.8-3.4-3.6-2.8-0.5
Delta time in closed arm before/after self-admin1.91.83.41.3-1.31.81.21.41.41.31.30.7
Delta time in open arm before/after self-admin0.30.31.1-0.20.1-1.0-0.1-0.4-0.5-0.4-0.4-0.7
Diff in mean of infusions in LGA sessions0.70.91.31.0-1.11.00.91.01.01.00.80.4
Delay discount exponential model param0.20.21.10.10.10.2-0.10.30.50.40.71.0
Extinction: sum of active levers before priming1.11.22.61.4-1.60.81.51.10.71.00.4-0.6
Active lever presses in extinction session 61.51.51.81.3-1.21.21.31.31.31.31.20.7
Bone: final force0.91.42.41.4-1.61.01.61.21.01.10.6-0.2
Bone: final moment0.81.42.41.4-1.51.01.51.21.01.10.7-0.1
Food consumed during 24 hour testing period0.10.20.3-0.50.60.2-0.6-0.3-0.1-0.3-0.00.5
Glucose3.65.68.6-2.11.6-2.9-1.6-2.4-2.7-2.5-2.7-2.3
Heart weight1.21.93.7-0.90.6-1.5-0.6-1.3-1.6-1.4-1.8-1.9
Delay discount hyperbolic model param0.30.31.30.20.00.30.00.40.60.60.81.1
Intermittent access intake day 1-15 change1.42.94.9-2.22.1-1.1-2.1-2.0-1.6-1.8-1.30.0
Intermittent access intake escalation1.22.44.1-2.02.0-1.0-1.9-1.8-1.4-1.6-1.20.2
Intermittent access intake escalation 21.92.13.3-1.81.8-1.1-1.7-1.7-1.4-1.5-1.2-0.0
Intermitt. access day 1 inactive lever presses0.00.00.1-0.10.20.1-0.3-0.1-0.1-0.10.10.1
Intermitt. access day 15 inactive lever presses1.42.83.8-1.71.5-1.6-1.4-1.8-2.0-1.8-1.8-1.4
Intermitt. access escalation Index1.21.73.4-1.71.8-0.8-1.8-1.4-0.9-1.2-0.70.6
Intermittent access day 1 total infusions3.25.28.3-1.81.5-2.9-1.4-2.2-2.7-2.4-2.6-2.6
Intermittent access day 15 total infusions5.58.210.0-3.23.0-2.8-2.9-3.1-3.1-3.1-2.7-1.4
Intermittent access terminal intake (last 3 days)5.97.89.5-2.92.6-3.0-2.5-3.0-3.1-3.0-2.8-1.9
Intermittent access total infusions4.25.06.4-2.21.9-2.4-1.8-2.4-2.5-2.5-2.4-1.9
Intermittent access day 1 locomotion1.92.54.5-1.31.1-2.1-1.1-1.5-1.8-1.6-1.6-1.6
Intermittent access day 15 total locomotion4.17.59.2-3.02.6-2.8-2.7-3.0-2.9-3.0-2.7-1.5
Intermittent access total locomotion8.810.612.7-3.53.0-3.5-3.1-3.6-3.5-3.6-3.3-2.0
Intermittent access standard deviation0.61.21.6-1.31.2-0.9-1.1-1.3-1.2-1.3-1.1-0.6
Left kidney weight0.94.16.1-2.42.5-1.6-2.3-2.3-2.0-2.2-1.8-0.6
Right kidney weight0.42.03.7-1.81.9-0.9-1.9-1.5-1.2-1.4-0.90.3
Cocaine induced anxiety0.00.10.2-0.20.1-0.3-0.1-0.2-0.3-0.3-0.3-0.4
Post-drug Anxiety0.20.20.40.7-0.60.30.70.50.40.50.3-0.1
Baseline Anxiety0.50.60.80.9-0.70.50.80.90.80.90.80.4
Tail length1.24.66.12.1-1.82.21.72.32.42.32.51.8
Length with tail2.711.613.63.6-3.43.73.53.63.73.63.31.9
Length without tail2.47.710.03.0-2.83.22.93.02.92.92.51.3
Times rat made contact with spout0.20.20.50.6-0.70.30.70.40.10.3-0.1-0.7
Lifetime Intake2.42.93.9-1.71.5-1.9-1.4-1.8-2.0-1.9-1.8-1.5
Liver weight, left0.20.30.8-0.60.90.1-0.8-0.4-0.1-0.20.10.8
Liver weight, right0.61.02.3-1.31.5-0.6-1.4-1.0-0.7-0.9-0.40.5
Locomotor activity0.40.61.4-0.91.2-0.5-1.2-0.7-0.4-0.6-0.10.6
Locomotor testing distance0.50.82.2-1.11.5-0.6-1.4-0.8-0.6-0.7-0.20.6
Locomotor testing rearing0.81.52.0-1.21.2-1.4-1.4-1.3-1.3-1.3-1.2-0.7
Locomotion in novel chamber6.48.211.0-3.13.0-3.3-3.0-3.1-3.0-3.0-2.6-1.1
Locomotion in novel chamber post-restriction2.64.25.8-2.42.3-1.9-2.3-2.3-2.1-2.2-1.7-0.5
Fecal boli incidents, locomotor time 10.00.00.1-0.30.30.0-0.3-0.2-0.2-0.2-0.0-0.0
Change in fecal boli incidents, locomotor task0.00.00.10.3-0.20.10.40.20.10.20.1-0.2
Time >=10cm from walls, locomotor time 13.53.76.5-1.61.3-2.5-1.3-1.9-2.2-2.0-2.1-1.9
Bouts of movement, locomotor time 11.92.15.61.2-1.02.41.11.31.61.41.41.3
Total resting periods, locomotor time 11.01.13.20.7-0.51.80.60.91.21.01.11.1
Rest time, locomotor task time 11.01.23.1-1.41.8-0.5-1.5-1.1-0.8-0.9-0.50.7
Distance moved, locomotor task time 10.30.41.80.1-0.4-0.70.2-0.2-0.5-0.4-0.8-1.4
Vertical activity count, locomotor time 10.61.31.8-1.10.8-1.4-0.9-1.2-1.3-1.3-1.2-1.1
Time >=10cm from walls, locomotor time 20.00.10.2-0.30.3-0.1-0.3-0.2-0.1-0.10.00.4
Bouts of movement, locomotor time 20.40.71.50.8-0.61.20.70.80.70.80.90.3
Total resting periods, locomotor time 20.10.21.00.4-0.31.00.40.40.30.40.50.1
Rest time, locomotor task time 22.53.24.0-1.81.8-2.0-1.6-1.9-2.0-1.9-1.8-1.1
Distance moved, locomotor task time 21.31.62.21.2-1.11.30.91.31.51.41.41.1
Vertical activity count, locomotor time 21.11.53.80.6-0.41.40.21.01.41.21.71.9
Light reinforcement 10.20.61.3-1.00.9-0.5-1.1-0.8-0.6-0.7-0.50.3
Light reinforcement 21.32.13.8-1.81.8-1.4-1.9-1.5-1.2-1.4-0.80.3
Bone: marrow area2.24.86.1-2.11.9-2.4-1.9-2.3-2.5-2.4-2.4-1.9
Bone: maximum diameter0.10.10.2-0.40.40.1-0.4-0.3-0.2-0.3-0.20.2
Bone: maximum force0.61.12.41.2-1.50.31.50.70.20.5-0.3-1.6
Bone: maximum moment0.61.02.31.2-1.50.41.50.80.30.6-0.2-1.4
Mean time between licks in bursts0.30.71.20.9-0.90.81.10.90.80.90.70.2
Mean num. licks in bursts0.00.00.20.1-0.0-0.5-0.1-0.0-0.2-0.0-0.0-0.3
Cd content in liver1.71.92.6-1.61.5-1.5-1.5-1.5-1.4-1.5-1.2-0.5
Co content in liver0.40.52.5-0.20.50.5-0.50.10.60.30.81.6
Cu content in liver0.00.00.1-0.20.2-0.3-0.2-0.1-0.1-0.1-0.10.0
Fe content in liver0.10.20.20.5-0.30.40.40.40.50.40.40.2
K content in liver0.20.20.30.5-0.60.20.60.30.20.3-0.1-0.5
Mg content in liver0.70.71.0-0.80.7-0.9-0.7-0.9-0.9-0.9-1.0-0.8
Mn content in liver1.71.92.81.7-1.61.21.61.51.31.51.10.2
Na content in liver0.30.31.00.10.10.9-0.00.40.60.50.71.0
Rb content in liver1.92.23.0-1.31.1-1.7-1.1-1.5-1.7-1.6-1.7-1.4
Se content in liver0.50.60.9-0.60.6-0.9-0.5-0.8-0.9-0.8-0.9-0.9
Sr content in liver2.92.53.11.5-1.61.71.41.71.81.71.71.2
Zn content in liver0.60.60.90.7-0.70.80.70.80.90.90.90.7
Bone: minimum diameter1.93.44.9-1.61.3-1.8-1.3-1.9-2.2-2.0-2.2-2.1
Time in familiar zone, hab. session 10.70.71.1-0.80.7-1.1-0.7-0.9-0.9-0.9-0.9-0.7
Time in novel zone, hab. session 10.10.10.30.2-0.20.50.30.30.30.30.30.3
Total zone transitions, hab. session 10.30.40.70.7-0.90.60.80.60.50.50.2-0.2
Total locomotion distance, hab. session 10.50.70.8-0.90.8-0.8-0.9-0.9-0.9-0.9-0.9-0.5
Locomotion velocity, hab. session 10.10.20.2-0.40.3-0.3-0.5-0.4-0.4-0.4-0.5-0.3
Time in familiar zone, hab. session 21.11.11.50.9-0.91.20.91.01.21.11.11.0
Time in novel zone, hab. session 20.70.71.6-0.50.3-1.0-0.3-0.7-1.0-0.8-1.1-1.3
Total zone transitions, hab. session 20.81.15.00.7-1.1-0.61.10.1-0.5-0.1-1.0-2.2
Total locomotion distance, hab. session 20.60.82.5-0.30.1-1.0-0.1-0.6-1.0-0.8-1.2-1.6
Locomotion velocity, hab. session 20.81.12.4-0.60.4-1.2-0.5-0.9-1.2-1.0-1.4-1.6
Novel to familiar place preference ratio0.10.10.60.1-0.2-0.10.3-0.1-0.3-0.2-0.5-0.8
Novelty place preference0.20.20.8-0.20.1-0.3-0.0-0.4-0.6-0.5-0.7-0.9
Time in novel zone, NPP test0.20.20.8-0.20.1-0.30.0-0.4-0.6-0.5-0.7-0.9
Total zone transitions, NPP test0.40.61.41.0-1.20.21.20.60.30.5-0.1-1.0
Total locomotion distance, NPP test0.20.30.7-0.20.1-0.6-0.1-0.4-0.6-0.5-0.7-0.8
Locomotion velocity, NPP test0.10.20.4-0.20.2-0.5-0.2-0.4-0.5-0.4-0.6-0.6
Intraocular pressure0.30.41.5-0.50.70.5-0.7-0.20.2-0.00.51.2
Delta distance traveled before/after self-admin0.10.10.30.2-0.10.30.20.30.40.40.50.6
Delta ambulatory time before/after self-admin0.20.20.50.4-0.10.30.40.50.50.50.70.7
Parametrial fat weight3.07.08.8-3.02.5-2.7-2.7-3.0-2.8-2.9-2.6-1.3
Pavlov. Cond. lever latency0.20.20.5-0.60.6-0.5-0.7-0.5-0.4-0.4-0.10.2
Pavlov. Cond. magazine entry latency0.50.61.6-0.50.3-0.8-0.2-0.7-0.9-0.8-1.1-1.2
Pavlov. Cond. change in total contacts0.70.81.0-0.80.7-1.0-0.7-0.9-1.0-0.9-1.0-0.8
Pavlov. Cond. index score0.00.00.1-0.20.2-0.0-0.1-0.3-0.2-0.3-0.3-0.2
Pavlov. Cond. latency score0.00.10.2-0.10.0-0.10.0-0.2-0.2-0.3-0.4-0.4
Pavlov. Cond. lever contacts0.00.00.10.2-0.30.20.30.10.10.1-0.2-0.3
Pavlov. Cond. magazine entry number0.00.10.10.3-0.30.10.20.30.20.30.20.1
Pavlov. Cond. intertrial magazine entries0.10.20.8-0.20.40.3-0.40.00.30.10.50.9
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.20.1-0.1-0.0-0.2-0.2-0.2-0.3-0.2
Pavlov. Cond. response bias0.00.00.1-0.20.20.1-0.1-0.2-0.1-0.2-0.10.1
Pavlov. Cond. lever latency0.00.00.2-0.10.1-0.4-0.2-0.1-0.2-0.1-0.1-0.1
Pavlov. Cond. magazine entry latency1.61.94.11.8-2.00.92.01.30.81.10.3-1.1
Pavlov. Cond. change in total contacts0.10.21.10.2-0.4-0.30.4-0.1-0.3-0.2-0.6-1.0
Pavlov. Cond. index score0.30.51.10.8-1.00.41.00.60.30.4-0.1-0.8
Pavlov. Cond. latency score0.30.30.80.7-0.90.40.90.50.30.4-0.0-0.6
Pavlov. Cond. lever contacts0.00.00.20.2-0.20.40.30.20.10.1-0.0-0.0
Pavlov. Cond. magazine entry number2.02.45.2-2.02.3-1.0-2.3-1.5-1.0-1.3-0.51.1
Pavlov. Cond. intertrial magazine entries0.81.32.4-1.41.5-0.9-1.5-1.2-0.9-1.1-0.70.3
Pavlov. Cond. lever-magazine prob. diff.0.50.71.51.0-1.20.51.20.70.40.60.1-0.8
Pavlov. Cond. response bias0.40.51.20.9-1.00.51.10.60.30.5-0.0-0.8
Time in closed arm before self-admin1.41.83.2-1.21.2-1.8-1.1-1.4-1.4-1.4-1.3-1.1
Time in closed arm after self-admin0.00.00.1-0.20.20.2-0.2-0.1-0.0-0.10.10.2
Time in open arm before self-admin1.51.63.81.2-1.01.90.81.31.41.31.21.1
Time in open arm after self-admin0.40.40.80.8-0.90.40.80.70.60.60.4-0.1
Bone: periosteal estimation0.20.30.5-0.60.5-0.3-0.5-0.6-0.6-0.7-0.7-0.4
Bone: periosteal perimeter0.40.71.1-0.60.5-0.8-0.5-0.8-1.0-0.9-1.1-1.1
Bone: post-yield work4.16.116.3-1.20.6-2.9-0.6-2.0-2.8-2.3-3.2-4.0
Progressive ratio test 1 active lever presses0.00.00.0-0.10.2-0.0-0.1-0.0-0.1-0.00.20.1
Progressive ratio test 1 breakpoint0.00.00.0-0.00.10.0-0.10.0-0.00.00.20.2
Progressive ratio test 1 inactive lever presses0.00.00.0-0.10.1-0.1-0.2-0.1-0.2-0.10.1-0.0
Progressive ratio test 2 active lever presses1.92.22.7-1.61.5-1.6-1.5-1.6-1.6-1.6-1.3-0.8
Progressive ratio test 2 breakpoint1.72.02.4-1.51.5-1.5-1.4-1.5-1.5-1.5-1.2-0.7
Progressive ratio test 2 inactive lever presses5.89.411.7-3.43.2-3.1-3.2-3.4-3.3-3.3-2.8-1.4
Incentive Sensitization - Responses0.30.41.2-0.2-0.0-0.80.0-0.4-0.6-0.5-0.8-1.1
Incentive Sensitization - Breakpoint0.40.51.2-0.40.2-1.0-0.2-0.6-0.8-0.7-0.9-1.1
Sum of active levers in priming session hrs 5-61.61.55.00.4-0.11.30.00.91.31.11.62.2
Progressive ratio0.81.25.60.5-0.8-1.20.9-0.1-0.8-0.3-1.2-2.4
Food seeking constrained by brief footshock0.00.10.10.3-0.4-0.00.30.20.10.10.0-0.3
Seeking ratio, punishment vs. effort0.40.62.7-0.70.80.8-0.9-0.20.3-0.00.71.6
Retroperitoneal fat weight7.029.740.8-6.46.3-5.2-6.2-6.0-5.4-5.7-4.6-1.2
Reaction time number correct0.61.11.50.9-0.71.20.71.11.21.11.21.1
Reaction time mean minus median0.71.83.61.8-1.60.91.91.51.01.30.9-0.4
Reaction time mean minus median AUC0.82.13.31.8-1.51.21.81.61.41.61.40.3
Reaction time num false alarms0.50.71.80.5-0.20.90.40.71.00.81.11.3
Reaction time num false alarms AUC1.01.52.11.1-0.91.31.11.31.41.41.51.2
Reaction time trials correct on left0.61.11.50.9-0.71.20.71.11.21.11.21.1
Reaction time trials on left0.71.41.81.1-0.81.30.91.21.41.31.41.2
Reaction time mean0.10.20.7-0.1-0.1-0.60.1-0.3-0.5-0.4-0.6-0.8
Reaction time mean AUC0.20.30.9-0.20.1-0.80.0-0.4-0.7-0.5-0.8-0.9
Median of all reaction times0.50.81.4-0.60.3-1.0-0.4-0.8-1.0-0.9-1.2-1.1
Reaction time omissions2.02.94.52.0-2.01.42.11.81.61.81.40.3
Reaction time false alarm rate0.20.30.60.4-0.30.60.40.60.70.60.80.8
Reaction time premature initiation rate2.33.24.92.2-2.11.22.02.11.82.01.60.4
Reaction time premature initiations3.56.28.12.8-2.62.12.52.82.62.82.51.2
Std. dev. reaction times0.20.51.11.0-0.80.11.10.70.40.60.4-0.4
Reaction time trials completed0.71.41.81.1-0.81.30.91.21.41.31.41.2
Reaction time trials AUC0.51.01.40.9-0.71.20.71.01.21.11.21.0
Run reversals in cocaine runway, females0.40.41.00.7-1.00.01.00.40.10.3-0.2-0.9
Run reversals in cocaine runway, males0.50.51.20.5-0.20.80.30.70.80.71.01.1
Latency to leave start box in cocaine runway0.91.02.1-0.70.4-1.2-0.4-0.9-1.2-1.0-1.4-1.4
Latency to leave start box in cocaine runway, F0.60.71.7-0.40.1-1.0-0.1-0.7-0.9-0.8-1.1-1.3
Latency to leave start box in cocaine runway, M0.00.00.1-0.00.0-0.2-0.1-0.1-0.2-0.1-0.2-0.3
Std. dev. time between licks in bursts1.52.13.21.2-1.01.81.11.41.71.51.61.5
Total sessions with >9 infusions0.00.10.20.2-0.2-0.30.20.1-0.10.0-0.1-0.5
Short access day 1 total inactive lever presses1.41.82.6-1.61.4-1.2-1.6-1.5-1.4-1.5-1.1-0.4
Short access day 10 total inactive lever presses0.00.00.0-0.0-0.0-0.1-0.0-0.1-0.2-0.1-0.1-0.2
Short access day 1 total infusions1.21.62.1-1.31.3-1.4-1.2-1.3-1.5-1.3-1.2-0.8
Short access day 10 total infusions1.21.53.8-0.60.3-1.7-0.3-1.0-1.4-1.1-1.5-2.0
Short access total infusions0.40.51.3-0.30.2-1.0-0.2-0.6-0.9-0.7-0.8-1.1
Short access day 1 locomotion1.01.31.8-1.21.1-1.4-1.1-1.2-1.2-1.2-1.0-0.7
Short access day 10 total locomotion0.81.53.8-1.10.8-1.9-0.9-1.2-1.3-1.3-1.3-1.1
Short access total locomotion1.31.52.7-1.21.0-1.6-1.1-1.3-1.4-1.3-1.2-0.9
One hour access (0.3 mA shock)4.95.76.9-2.62.6-2.6-2.4-2.6-2.5-2.5-2.1-1.0
Compulsive drug intake3.84.55.82.2-1.82.31.72.32.32.32.41.6
One hour access (shock baseline)5.99.011.4-3.43.2-3.1-3.1-3.3-3.2-3.2-2.7-1.2
Social response proportion0.30.30.70.7-0.8-0.00.80.50.30.40.1-0.5
Social responses0.70.91.11.0-1.00.90.91.01.11.01.00.6
Social time0.50.71.01.0-0.90.91.00.90.90.90.70.1
Soleus weight2.47.013.3-3.43.5-1.9-3.7-2.9-2.2-2.6-1.40.9
Bone: stiffness0.40.72.90.7-1.00.01.00.2-0.20.0-0.7-1.7
Tibialis anterior weight10.435.244.96.0-6.06.75.76.36.46.35.83.7
Time to tail flick, vehicle, before self-admin0.40.52.30.1-0.3-0.50.3-0.2-0.6-0.4-0.9-1.5
Time to tail flick, vehicle, after self-admin0.60.82.01.1-1.4-0.21.30.70.20.5-0.1-1.2
Time to tail flick, test, before self-admin1.81.93.3-1.10.6-1.5-0.8-1.4-1.6-1.5-1.7-1.8
Time to tail flick, test, after self-admin0.00.10.30.00.20.50.10.10.20.10.10.2
Delta time to tail flick, vehicle, before/after SA0.60.51.40.9-1.20.41.00.70.50.70.4-0.2
Delta time to tail flick, test, before/after SA3.33.46.31.2-0.52.30.91.72.11.92.32.5
Tibia length0.61.52.80.8-0.91.50.51.11.41.21.51.7
Ambulatory time before self-admin0.20.31.1-0.1-0.2-0.60.0-0.4-0.5-0.4-0.7-1.0
Ambulatory time after self-admin1.21.42.2-1.10.8-1.5-0.8-1.2-1.3-1.3-1.3-1.1
Bone: tissue strength0.30.30.4-0.40.3-0.4-0.3-0.5-0.6-0.6-0.6-0.6
Total heroin consumption3.54.15.62.4-2.22.02.42.21.92.11.70.5
Bone: trabecular number0.71.14.90.4-0.8-1.20.8-0.1-0.7-0.4-1.2-2.2
Bone: trabecular spacing0.20.31.0-0.40.60.6-0.6-0.10.1-0.00.41.0
Bone: trabecular thickness1.31.63.0-0.80.5-1.7-0.5-1.1-1.4-1.2-1.6-1.7
Bone: trabecular tissue density3.34.810.1-2.93.1-1.2-3.2-2.3-1.7-2.0-1.01.0
Water consumed over 24 hours0.40.51.10.9-1.00.71.00.70.50.60.2-0.5
Number of responses in last shaping day0.20.20.30.4-0.40.50.40.40.40.40.50.4