Hub : Genes

Gstp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Gstp1 0.15 0.1 1.7e-09 0.1 0.11 0.11 0.1 1.6e-08 4.3e-09 7.5e-09 8.5e-09
2 Liver mRNA stability Gstp1 0.15 0.08 1.2e-09 0.06 0.05 0.06 0.05 2.6e-07 1.1e-06 3.7e-07 1.6e-06
3 BLA gene expression Gstp1 0.22 0.17 6.5e-08 0.13 0.13 0.17 0.12 3.0e-07 3.0e-07 2.9e-09 5.8e-07
4 Brain gene expression Gstp1 0.32 0.15 0.0e+00 0.2 0.2 0.2 0.2 6.8e-19 2.4e-18 1.3e-18 7.5e-19
5 NAcc gene expression Gstp1 0.19 0.12 0.0e+00 0.13 0.17 0.17 0.17 8.0e-19 7.0e-25 2.2e-24 8.3e-25
6 PL gene expression Gstp1 0.08 0.05 1.3e-08 0.07 0.07 0.07 0.07 5.7e-08 2.4e-08 2.3e-08 3.3e-08
7 IC gene expression Gstp1 0.14 0.1 1.4e-04 0.04 0.06 0.06 0.04 5.8e-03 1.7e-03 2.2e-03 8.1e-03
8 OFC gene expression Gstp1 0.26 0.16 3.4e-04 0.1 -0.01 0.1 -0.01 2.2e-03 5.4e-01 2.3e-03 7.3e-01
9 Adipose gene expression Gstp1 0.08 0.05 2.5e-08 0.02 0.06 0.06 0.06 9.6e-04 3.8e-07 3.9e-07 8.3e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.71.35.60.30.71.4-0.7-0.30.9-0.51.3-2.4
Area under the delay curve0.30.41.5-0.2-0.00.2-0.0-0.50.7-0.60.9-1.2
BMI with tail0.62.16.01.72.20.2-2.10.9-0.00.60.5-2.4
BMI without tail0.41.94.21.92.0-0.4-1.91.4-0.91.2-0.6-0.9
Body weight1.88.014.13.53.7-2.2-3.73.0-2.52.8-1.9-0.4
Weight adjusted by age0.41.32.11.21.4-1.1-1.11.2-1.21.2-1.00.5
Bone surface1.01.94.41.62.10.0-2.11.0-0.30.70.4-2.1
Bone volume0.50.94.20.60.90.8-0.90.00.5-0.21.0-2.0
Breakpoint value in progressive ratio session1.11.93.51.71.9-1.1-1.71.6-1.31.4-1.00.0
Number of licking bursts0.00.10.10.00.1-0.3-0.3-0.00.1-0.10.3-0.4
Context. condit. distance diff. score1.01.21.5-1.2-1.21.21.0-1.21.2-1.21.1-0.6
Locomotion velocity, session 10.00.00.00.00.00.0-0.2-0.00.0-0.00.1-0.1
Locomotion distance, session 10.40.52.10.40.60.4-0.70.00.4-0.20.7-1.5
Locomotion velocity, session 21.82.23.11.71.8-1.4-1.71.6-1.51.5-1.20.3
Locomotion distance, session 20.40.61.41.01.2-0.4-1.10.7-0.50.6-0.1-0.7
Locomotion velocity, session 30.70.82.6-0.3-0.11.0-0.1-0.61.0-0.81.2-1.6
Locomotion distance, session 30.10.10.2-0.1-0.00.4-0.1-0.20.3-0.20.3-0.5
Stereotopy head waving bouts, day 31.11.32.3-0.8-0.61.30.7-1.01.3-1.11.4-1.5
Stereotopy head waving duration, day 31.41.82.3-1.2-1.11.41.1-1.41.5-1.41.5-1.2
Locomotion velocity, session 70.40.41.5-0.20.00.90.0-0.40.7-0.50.8-1.2
Locomotion distance, session 70.10.20.50.60.7-0.0-0.60.4-0.30.4-0.2-0.3
Stereotopy head waving bouts, day 71.01.12.3-0.7-0.51.30.5-1.01.3-1.11.3-1.5
Stereotopy head waving duration, day 70.30.41.90.30.50.4-0.6-0.00.4-0.20.6-1.4
Locomotion velocity, session 81.21.52.21.41.5-1.3-1.51.3-1.21.2-0.90.1
Locomotion distance, session 80.40.50.8-0.6-0.50.80.4-0.80.8-0.80.9-0.8
Degree of sensitization distance0.10.10.40.50.60.1-0.50.3-0.10.20.0-0.5
Degree of sensitization stereotypy0.10.10.70.20.30.3-0.3-0.10.3-0.10.3-0.9
Conditioned locomotion3.84.55.91.91.7-2.4-1.72.2-2.42.3-2.31.9
Cocaine response after cond. corrected0.10.20.3-0.4-0.40.50.4-0.40.4-0.40.3-0.3
Cocaine response after cond. not corrected0.20.30.6-0.4-0.30.80.3-0.60.7-0.60.6-0.7
Cocaine response before conditioning0.00.00.10.10.2-0.1-0.30.00.0-0.00.2-0.4
Saline control response2.33.24.72.12.2-1.9-2.21.9-1.71.8-1.30.2
Bone: connectivity density1.11.74.71.51.90.4-1.90.8-0.10.50.5-2.2
Bone: cortical apparent density0.50.81.00.80.7-0.9-0.70.9-1.01.0-1.00.8
Bone: cortical area0.91.42.71.00.9-1.6-1.01.2-1.31.2-1.21.0
Bone: cortical porosity0.00.00.10.10.1-0.3-0.10.00.00.00.1-0.2
Bone: cortical porosity0.30.30.60.60.6-0.8-0.60.5-0.50.5-0.40.0
Bone: cortical thickness6.510.815.43.12.9-3.9-2.93.4-3.63.5-3.42.6
Bone: cortical thickness2.32.83.41.71.6-1.8-1.61.8-1.81.8-1.71.1
Bone: cortical tissue density0.71.11.41.00.9-1.0-0.91.1-1.21.1-1.10.9
Condit. Reinf. active minus inactive responses0.10.10.50.10.30.4-0.3-0.00.2-0.10.3-0.7
Condit. Reinf. active-inactive response ratio0.20.20.4-0.2-0.20.60.1-0.40.5-0.40.5-0.6
Condit. Reinf. active responses0.00.00.1-0.00.00.2-0.1-0.10.1-0.10.1-0.3
Condit. Reinf. inactive responses0.00.00.1-0.3-0.30.10.3-0.20.1-0.2-0.00.2
Incentive salience index mean0.10.10.30.20.40.1-0.40.10.10.00.2-0.6
Condit. Reinf. lever presses0.00.10.20.20.2-0.4-0.30.2-0.30.2-0.20.2
Condit. Reinf. active minus inactive responses1.11.62.9-1.0-0.81.70.7-1.21.5-1.31.5-1.5
Condit. Reinf. active-inactive response ratio1.72.73.8-1.6-1.52.01.4-1.71.8-1.71.7-1.2
Condit. Reinf. active responses0.71.13.0-0.4-0.21.40.1-0.81.2-0.91.3-1.7
Condit. Reinf. inactive responses0.30.51.00.91.0-0.2-1.00.5-0.20.40.1-0.9
Condit. Reinf. lever presses0.30.41.30.70.90.1-0.90.30.10.20.4-1.1
Condit. Reinf. lever reinforcers received0.60.83.0-0.10.11.2-0.2-0.51.0-0.71.2-1.7
Conditioned reinforcement - actives0.10.20.9-0.3-0.4-0.60.5-0.1-0.20.0-0.51.0
Conditioned reinforcement - inactives1.33.64.7-2.2-2.01.92.1-2.12.0-2.01.6-0.7
Conditioned locomotion5.27.712.1-3.5-3.52.33.5-3.12.5-2.81.90.2
Patch foraging indifference point 0 sec0.20.60.9-0.7-0.91.00.8-0.70.8-0.70.5-0.3
Patch foraging indifference point AUC0.81.83.41.21.3-1.9-1.11.3-1.51.4-1.21.1
Delay disc. indifference point, 0s delay0.91.03.0-0.4-0.30.90.1-0.81.2-0.91.5-1.7
Delay disc. indifference point, 16s delay0.91.21.7-1.3-1.20.61.2-1.31.2-1.31.1-0.6
Delay disc. indifference point, 2s delay0.80.91.4-0.9-0.61.00.7-1.01.1-1.11.2-1.1
Delay disc. indifference point, 24s delay0.20.31.00.30.1-1.0-0.20.5-0.50.5-0.60.6
Delay disc. indifference point, 4s delay0.10.20.80.00.30.1-0.2-0.20.3-0.30.6-0.9
Delay disc. indifference point, 8s delay0.10.10.60.10.0-0.3-0.3-0.10.3-0.20.3-0.7
Indifference point function ln k1.64.97.2-2.5-2.72.52.7-2.32.1-2.21.5-0.3
Indifference point function log k1.64.97.2-2.5-2.72.52.7-2.32.1-2.21.5-0.3
Patch foraging total patch changes 0 sec0.00.10.3-0.3-0.60.40.4-0.20.2-0.2-0.10.3
Patch foraging total patch changes 12 sec2.02.63.71.91.9-1.7-1.71.7-1.61.7-1.30.4
Patch foraging total patch changes 18 sec0.10.20.50.50.7-0.5-0.60.4-0.30.4-0.1-0.2
Patch foraging total patch changes 24 sec0.31.11.41.11.0-1.2-0.91.1-1.21.2-1.10.8
Patch foraging total patch changes 6 sec0.30.51.11.00.9-0.3-1.10.7-0.30.6-0.1-0.6
Patch foraging time to switch 0 sec0.31.03.60.91.5-0.2-1.30.40.10.10.7-1.9
Patch foraging water rate 0 sec0.72.86.7-2.0-2.60.82.4-1.30.6-1.0-0.22.1
Patch foraging water rate 12 sec1.14.310.8-2.6-3.31.23.0-1.91.1-1.50.31.9
Patch foraging water rate 18 sec0.41.02.2-1.3-1.50.71.3-1.00.7-0.90.30.6
Patch foraging water rate 24 sec0.91.33.4-1.3-1.80.21.7-0.70.2-0.5-0.51.8
Patch foraging water rate 6 sec0.60.93.0-1.0-1.3-0.21.4-0.5-0.1-0.3-0.51.7
Seeking ratio, delayed vs. immediate footshock0.20.41.4-0.20.00.30.0-0.40.7-0.60.9-1.2
Distance traveled before self-admin0.10.10.60.00.20.4-0.1-0.20.2-0.20.4-0.8
Distance traveled after self-admin0.00.00.10.10.10.2-0.20.0-0.00.00.0-0.2
Extensor digitorum longus weight6.927.636.55.86.0-5.5-5.85.6-5.35.5-4.61.9
Bone: elastic displacement1.11.44.50.3-0.0-1.50.00.8-1.31.0-1.62.1
Bone: elastic work3.04.06.01.91.7-2.4-1.72.1-2.22.1-2.11.6
Bone: endosteal estimation1.94.65.9-2.0-1.82.31.9-2.32.4-2.32.4-1.8
Bone: endosteal perimeter3.99.512.2-2.9-2.73.42.7-3.23.5-3.33.4-2.6
Epididymis fat weight2.311.716.7-4.1-4.03.04.0-3.83.4-3.62.8-0.5
Delta time in closed arm before/after self-admin1.91.83.41.31.3-1.8-1.21.4-1.41.3-1.30.7
Delta time in open arm before/after self-admin0.20.31.1-0.2-0.11.00.1-0.40.5-0.40.4-0.7
Diff in mean of infusions in LGA sessions0.50.91.31.01.1-1.0-0.91.0-1.01.0-0.80.4
Delay discount exponential model param0.20.21.10.1-0.1-0.20.10.3-0.50.4-0.71.0
Extinction: sum of active levers before priming0.81.22.61.41.6-0.8-1.51.1-0.71.0-0.4-0.6
Active lever presses in extinction session 61.51.51.81.31.2-1.2-1.31.3-1.31.3-1.20.7
Bone: final force0.81.42.41.41.6-1.0-1.61.2-1.01.1-0.6-0.2
Bone: final moment0.81.42.41.41.5-1.0-1.51.2-1.01.1-0.7-0.1
Food consumed during 24 hour testing period0.10.20.3-0.5-0.6-0.20.6-0.30.1-0.30.00.5
Glucose3.55.68.6-2.1-1.62.91.6-2.42.7-2.52.7-2.3
Heart weight1.21.93.7-0.9-0.61.50.6-1.31.6-1.41.8-1.9
Delay discount hyperbolic model param0.30.31.30.2-0.0-0.3-0.00.4-0.60.6-0.81.1
Intermittent access intake day 1-15 change0.52.94.9-2.2-2.11.12.1-2.01.6-1.81.30.0
Intermittent access intake escalation0.42.44.1-2.0-2.01.01.9-1.81.4-1.61.20.2
Intermittent access intake escalation 21.32.13.3-1.8-1.81.11.7-1.71.4-1.51.2-0.0
Intermitt. access day 1 inactive lever presses0.00.00.1-0.1-0.2-0.10.3-0.10.1-0.1-0.10.1
Intermitt. access day 15 inactive lever presses0.52.83.8-1.7-1.51.61.4-1.82.0-1.81.8-1.4
Intermitt. access escalation Index0.51.73.4-1.7-1.80.81.8-1.40.9-1.20.70.6
Intermittent access day 1 total infusions1.75.28.3-1.8-1.52.91.4-2.22.7-2.42.6-2.6
Intermittent access day 15 total infusions3.38.210.0-3.2-3.02.82.9-3.13.1-3.12.7-1.4
Intermittent access terminal intake (last 3 days)4.47.89.5-2.9-2.63.02.5-3.03.1-3.02.8-1.9
Intermittent access total infusions4.25.06.4-2.2-1.92.41.8-2.42.5-2.52.4-1.9
Intermittent access day 1 locomotion1.32.54.5-1.3-1.12.11.1-1.51.8-1.61.6-1.6
Intermittent access day 15 total locomotion1.97.59.2-3.0-2.62.82.7-3.02.9-3.02.7-1.5
Intermittent access total locomotion8.810.612.7-3.5-3.03.53.1-3.63.5-3.63.3-2.0
Intermittent access standard deviation0.21.21.6-1.3-1.20.91.1-1.31.2-1.31.1-0.6
Left kidney weight0.54.16.1-2.4-2.51.62.3-2.32.1-2.21.8-0.6
Right kidney weight0.32.03.7-1.8-1.90.91.9-1.51.2-1.40.90.3
Cocaine induced anxiety0.00.10.2-0.2-0.10.30.1-0.20.3-0.30.3-0.4
Post-drug Anxiety0.20.20.40.70.6-0.3-0.70.5-0.40.5-0.3-0.1
Baseline Anxiety0.30.60.80.90.7-0.5-0.80.9-0.80.9-0.80.4
Tail length0.94.66.12.11.8-2.2-1.72.3-2.42.3-2.51.8
Length with tail2.611.613.63.63.4-3.7-3.53.6-3.73.6-3.31.9
Length without tail1.57.710.03.02.8-3.2-2.93.0-2.92.9-2.51.3
Times rat made contact with spout0.20.20.50.60.7-0.3-0.70.4-0.10.30.1-0.7
Lifetime Intake2.42.93.9-1.7-1.51.91.4-1.82.0-1.91.8-1.5
Liver weight, left0.20.30.8-0.6-0.9-0.10.8-0.40.1-0.2-0.10.8
Liver weight, right0.61.02.3-1.3-1.50.61.4-1.00.7-0.90.40.5
Locomotor activity0.40.61.4-0.9-1.20.51.2-0.70.4-0.60.10.6
Locomotor testing distance0.30.82.2-1.1-1.50.61.4-0.80.6-0.70.20.6
Locomotor testing rearing0.41.52.0-1.2-1.21.41.4-1.31.3-1.31.2-0.7
Locomotion in novel chamber6.18.211.0-3.1-3.03.33.0-3.13.0-3.02.6-1.1
Locomotion in novel chamber post-restriction1.44.25.8-2.4-2.31.92.3-2.32.1-2.21.7-0.5
Fecal boli incidents, locomotor time 10.00.00.1-0.3-0.3-0.00.3-0.20.2-0.20.0-0.0
Change in fecal boli incidents, locomotor task0.00.00.10.30.2-0.1-0.40.2-0.10.2-0.1-0.2
Time >=10cm from walls, locomotor time 13.03.76.5-1.6-1.32.51.3-1.92.2-2.02.1-1.9
Bouts of movement, locomotor time 11.62.15.61.21.0-2.4-1.11.3-1.61.4-1.41.3
Total resting periods, locomotor time 11.01.13.20.70.5-1.8-0.60.9-1.21.0-1.11.1
Rest time, locomotor task time 10.81.23.1-1.4-1.80.51.5-1.10.8-0.90.50.7
Distance moved, locomotor task time 10.10.41.80.10.40.7-0.2-0.20.5-0.40.8-1.4
Vertical activity count, locomotor time 10.21.31.8-1.1-0.81.40.9-1.21.3-1.31.2-1.1
Time >=10cm from walls, locomotor time 20.00.10.2-0.3-0.30.10.3-0.20.1-0.1-0.00.4
Bouts of movement, locomotor time 20.20.71.50.80.6-1.2-0.70.8-0.70.8-0.90.3
Total resting periods, locomotor time 20.10.21.00.40.3-1.0-0.40.4-0.30.4-0.50.1
Rest time, locomotor task time 21.93.24.0-1.8-1.82.01.6-1.92.0-1.91.8-1.1
Distance moved, locomotor task time 21.21.62.21.21.1-1.3-0.91.3-1.51.4-1.41.1
Vertical activity count, locomotor time 20.71.53.80.60.4-1.4-0.21.0-1.41.2-1.71.9
Light reinforcement 10.10.61.3-1.0-0.90.51.1-0.80.6-0.70.50.3
Light reinforcement 20.92.13.8-1.8-1.81.41.9-1.51.2-1.40.80.3
Bone: marrow area2.04.86.1-2.1-1.92.41.9-2.32.5-2.42.4-1.9
Bone: maximum diameter0.00.10.2-0.4-0.4-0.10.4-0.30.2-0.30.20.2
Bone: maximum force0.51.12.41.21.5-0.3-1.50.7-0.20.50.3-1.6
Bone: maximum moment0.51.02.31.21.5-0.4-1.50.8-0.30.60.2-1.4
Mean time between licks in bursts0.10.71.20.90.9-0.8-1.10.9-0.80.9-0.70.2
Mean num. licks in bursts0.00.00.20.10.00.50.1-0.00.2-0.00.0-0.3
Cd content in liver1.71.92.6-1.6-1.51.51.5-1.51.4-1.51.2-0.5
Co content in liver0.40.52.5-0.2-0.5-0.50.50.1-0.60.3-0.81.6
Cu content in liver0.00.00.1-0.2-0.20.30.2-0.10.1-0.10.10.0
Fe content in liver0.10.20.20.50.3-0.4-0.40.4-0.50.4-0.40.2
K content in liver0.20.20.30.50.6-0.2-0.60.3-0.20.30.1-0.5
Mg content in liver0.60.71.0-0.8-0.70.90.7-0.90.9-0.91.0-0.8
Mn content in liver1.71.92.81.71.6-1.2-1.61.5-1.31.5-1.10.2
Na content in liver0.30.31.00.1-0.1-0.90.00.4-0.60.5-0.71.0
Rb content in liver1.92.23.0-1.3-1.11.71.1-1.51.7-1.61.7-1.4
Se content in liver0.50.60.9-0.6-0.60.90.5-0.80.9-0.80.9-0.9
Sr content in liver2.92.53.11.51.6-1.7-1.41.7-1.81.7-1.71.2
Zn content in liver0.60.60.90.70.7-0.8-0.70.8-0.90.9-0.90.7
Bone: minimum diameter1.83.44.9-1.6-1.31.81.3-1.92.2-2.02.2-2.1
Time in familiar zone, hab. session 10.70.71.1-0.8-0.71.10.7-0.90.9-0.90.9-0.7
Time in novel zone, hab. session 10.10.10.30.20.2-0.5-0.30.3-0.30.3-0.30.3
Total zone transitions, hab. session 10.30.40.70.70.9-0.6-0.80.6-0.50.5-0.2-0.2
Total locomotion distance, hab. session 10.50.70.8-0.9-0.80.80.9-0.90.9-0.90.9-0.5
Locomotion velocity, hab. session 10.10.20.2-0.4-0.30.30.5-0.40.4-0.40.5-0.3
Time in familiar zone, hab. session 21.01.11.50.90.9-1.2-0.91.0-1.21.1-1.11.0
Time in novel zone, hab. session 20.60.71.6-0.5-0.31.00.3-0.71.0-0.81.1-1.3
Total zone transitions, hab. session 20.81.15.00.71.10.6-1.10.10.5-0.11.0-2.2
Total locomotion distance, hab. session 20.60.82.5-0.3-0.11.00.1-0.61.0-0.81.2-1.6
Locomotion velocity, hab. session 20.81.12.4-0.6-0.41.20.5-0.91.2-1.01.4-1.6
Novel to familiar place preference ratio0.10.10.60.10.20.1-0.3-0.10.3-0.20.5-0.8
Novelty place preference0.20.20.8-0.2-0.10.30.0-0.40.6-0.50.7-0.9
Time in novel zone, NPP test0.20.20.8-0.2-0.10.3-0.0-0.40.6-0.50.7-0.9
Total zone transitions, NPP test0.40.61.41.01.2-0.2-1.20.6-0.30.50.1-1.0
Total locomotion distance, NPP test0.20.30.7-0.2-0.10.60.1-0.40.6-0.50.7-0.8
Locomotion velocity, NPP test0.10.20.4-0.2-0.20.50.2-0.40.5-0.40.6-0.6
Intraocular pressure0.20.41.5-0.5-0.7-0.50.7-0.2-0.2-0.0-0.51.2
Delta distance traveled before/after self-admin0.10.10.30.20.1-0.3-0.20.3-0.40.4-0.50.6
Delta ambulatory time before/after self-admin0.10.20.50.40.1-0.3-0.40.5-0.50.5-0.70.7
Parametrial fat weight3.07.08.8-3.0-2.52.72.7-3.02.8-2.92.6-1.3
Pavlov. Cond. lever latency0.20.20.5-0.6-0.60.50.7-0.50.4-0.40.10.2
Pavlov. Cond. magazine entry latency0.50.61.6-0.5-0.30.80.2-0.70.9-0.81.1-1.2
Pavlov. Cond. change in total contacts0.70.81.0-0.8-0.71.00.7-0.91.0-0.91.0-0.8
Pavlov. Cond. index score0.00.00.1-0.2-0.20.00.1-0.30.2-0.30.3-0.2
Pavlov. Cond. latency score0.00.10.2-0.1-0.00.1-0.0-0.20.2-0.30.4-0.4
Pavlov. Cond. lever contacts0.00.00.10.20.3-0.2-0.30.1-0.10.10.2-0.3
Pavlov. Cond. magazine entry number0.00.10.10.30.3-0.1-0.20.3-0.20.3-0.20.1
Pavlov. Cond. intertrial magazine entries0.10.20.8-0.2-0.4-0.30.40.0-0.30.1-0.50.9
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.2-0.10.10.0-0.20.2-0.20.3-0.2
Pavlov. Cond. response bias0.00.00.1-0.2-0.2-0.10.1-0.20.1-0.20.10.1
Pavlov. Cond. lever latency0.00.00.2-0.1-0.10.40.2-0.10.2-0.10.1-0.1
Pavlov. Cond. magazine entry latency1.31.94.11.82.0-0.9-2.01.3-0.81.1-0.3-1.1
Pavlov. Cond. change in total contacts0.10.21.10.20.40.3-0.4-0.10.3-0.20.6-1.0
Pavlov. Cond. index score0.30.51.10.81.0-0.4-1.00.6-0.30.40.1-0.8
Pavlov. Cond. latency score0.20.30.80.70.9-0.4-0.90.5-0.30.40.0-0.6
Pavlov. Cond. lever contacts0.00.00.20.20.2-0.4-0.30.2-0.10.10.0-0.0
Pavlov. Cond. magazine entry number1.92.45.2-2.0-2.31.02.3-1.51.0-1.30.51.1
Pavlov. Cond. intertrial magazine entries0.61.32.4-1.4-1.50.91.5-1.20.9-1.10.70.3
Pavlov. Cond. lever-magazine prob. diff.0.40.71.51.01.2-0.5-1.20.7-0.40.6-0.1-0.8
Pavlov. Cond. response bias0.40.51.20.91.0-0.5-1.10.6-0.30.50.0-0.8
Time in closed arm before self-admin1.01.83.2-1.2-1.21.81.1-1.41.4-1.41.3-1.1
Time in closed arm after self-admin0.00.00.1-0.2-0.2-0.20.2-0.10.0-0.1-0.10.2
Time in open arm before self-admin1.41.63.81.21.0-1.9-0.81.3-1.41.3-1.21.1
Time in open arm after self-admin0.40.40.80.80.9-0.4-0.80.7-0.60.6-0.4-0.1
Bone: periosteal estimation0.10.30.5-0.6-0.50.30.5-0.60.6-0.70.7-0.4
Bone: periosteal perimeter0.30.71.1-0.6-0.50.80.5-0.81.0-0.91.1-1.1
Bone: post-yield work3.56.116.3-1.2-0.62.90.6-2.02.8-2.33.2-4.0
Progressive ratio test 1 active lever presses0.00.00.0-0.1-0.20.00.1-0.00.1-0.0-0.20.1
Progressive ratio test 1 breakpoint0.00.00.0-0.0-0.1-0.00.10.00.00.0-0.20.2
Progressive ratio test 1 inactive lever presses0.00.00.0-0.1-0.10.10.2-0.10.2-0.1-0.1-0.0
Progressive ratio test 2 active lever presses1.62.22.7-1.6-1.51.61.5-1.61.6-1.61.3-0.8
Progressive ratio test 2 breakpoint1.62.02.4-1.5-1.51.51.4-1.51.5-1.51.2-0.7
Progressive ratio test 2 inactive lever presses3.09.411.7-3.4-3.23.13.2-3.43.3-3.32.8-1.4
Incentive Sensitization - Responses0.10.41.2-0.20.00.8-0.0-0.40.6-0.50.8-1.1
Incentive Sensitization - Breakpoint0.20.51.2-0.4-0.21.00.2-0.60.8-0.70.9-1.1
Sum of active levers in priming session hrs 5-61.61.55.00.40.1-1.3-0.00.9-1.31.1-1.62.2
Progressive ratio0.41.25.60.50.81.2-0.9-0.10.8-0.31.2-2.4
Food seeking constrained by brief footshock0.00.10.10.30.40.0-0.30.2-0.10.1-0.0-0.3
Seeking ratio, punishment vs. effort0.30.62.7-0.7-0.8-0.80.9-0.2-0.3-0.0-0.71.6
Retroperitoneal fat weight6.629.740.8-6.4-6.35.26.2-6.05.4-5.74.6-1.2
Reaction time number correct0.31.11.50.90.7-1.2-0.71.1-1.21.1-1.21.1
Reaction time mean minus median0.31.83.61.81.6-0.9-1.91.5-1.01.3-0.9-0.4
Reaction time mean minus median AUC0.32.13.31.81.5-1.2-1.81.6-1.41.6-1.40.3
Reaction time num false alarms0.40.71.80.50.2-0.9-0.40.7-1.00.8-1.11.3
Reaction time num false alarms AUC0.71.52.11.10.9-1.3-1.11.3-1.41.4-1.51.2
Reaction time trials correct on left0.31.11.50.90.7-1.2-0.71.1-1.21.1-1.21.1
Reaction time trials on left0.41.41.81.10.8-1.3-0.91.2-1.41.3-1.41.2
Reaction time mean0.10.20.7-0.10.10.6-0.1-0.30.5-0.40.6-0.8
Reaction time mean AUC0.10.30.9-0.2-0.10.8-0.0-0.40.7-0.50.8-0.9
Median of all reaction times0.50.81.4-0.6-0.31.00.4-0.81.0-0.91.2-1.1
Reaction time omissions1.82.94.52.02.0-1.4-2.11.8-1.61.8-1.40.3
Reaction time false alarm rate0.20.30.60.40.3-0.6-0.40.6-0.70.6-0.80.8
Reaction time premature initiation rate2.13.24.92.22.1-1.2-2.02.1-1.82.0-1.60.4
Reaction time premature initiations2.06.28.12.82.6-2.1-2.52.8-2.62.8-2.51.2
Std. dev. reaction times0.10.51.11.00.8-0.1-1.10.7-0.40.6-0.4-0.4
Reaction time trials completed0.41.41.81.10.8-1.3-0.91.2-1.41.3-1.41.2
Reaction time trials AUC0.31.01.40.90.7-1.2-0.71.0-1.21.1-1.21.0
Run reversals in cocaine runway, females0.40.41.00.71.0-0.0-1.00.4-0.10.30.2-0.9
Run reversals in cocaine runway, males0.50.51.20.50.2-0.8-0.30.7-0.80.7-1.01.1
Latency to leave start box in cocaine runway0.81.02.1-0.7-0.41.20.4-0.91.2-1.01.4-1.4
Latency to leave start box in cocaine runway, F0.50.71.7-0.4-0.11.00.1-0.70.9-0.81.1-1.3
Latency to leave start box in cocaine runway, M0.00.00.1-0.0-0.00.20.1-0.10.2-0.10.2-0.3
Std. dev. time between licks in bursts1.12.13.21.21.0-1.8-1.11.4-1.71.5-1.61.5
Total sessions with >9 infusions0.00.10.20.20.20.3-0.20.10.10.00.1-0.5
Short access day 1 total inactive lever presses0.91.82.6-1.6-1.41.21.6-1.51.4-1.51.1-0.4
Short access day 10 total inactive lever presses0.00.00.0-0.00.00.10.0-0.10.2-0.10.1-0.2
Short access day 1 total infusions0.81.62.1-1.3-1.31.41.2-1.31.5-1.31.2-0.8
Short access day 10 total infusions0.91.53.8-0.6-0.31.70.3-1.01.4-1.11.5-2.0
Short access total infusions0.40.51.3-0.3-0.21.00.2-0.60.9-0.70.8-1.1
Short access day 1 locomotion0.81.31.8-1.2-1.11.41.1-1.21.2-1.21.0-0.7
Short access day 10 total locomotion0.41.53.8-1.1-0.81.90.9-1.21.3-1.31.3-1.1
Short access total locomotion1.01.52.7-1.2-1.01.61.1-1.31.4-1.31.2-0.9
One hour access (0.3 mA shock)4.85.76.9-2.6-2.62.62.4-2.62.5-2.52.1-1.0
Compulsive drug intake3.14.55.82.21.8-2.3-1.72.3-2.32.3-2.41.6
One hour access (shock baseline)3.49.011.4-3.4-3.23.13.1-3.33.2-3.22.7-1.2
Social response proportion0.20.30.70.70.80.0-0.80.5-0.30.4-0.1-0.5
Social responses0.70.91.11.01.0-0.9-0.91.0-1.11.0-1.00.6
Social time0.40.71.01.00.9-0.9-1.00.9-0.90.9-0.70.1
Soleus weight2.47.013.3-3.4-3.51.93.7-2.92.2-2.61.40.9
Bone: stiffness0.40.72.90.71.0-0.0-1.00.20.20.00.7-1.7
Tibialis anterior weight10.235.244.96.06.0-6.7-5.76.3-6.46.3-5.83.7
Time to tail flick, vehicle, before self-admin0.40.52.30.10.30.5-0.3-0.20.6-0.40.9-1.5
Time to tail flick, vehicle, after self-admin0.40.82.01.11.40.2-1.30.7-0.20.50.1-1.2
Time to tail flick, test, before self-admin1.71.93.3-1.1-0.61.50.8-1.41.6-1.51.7-1.8
Time to tail flick, test, after self-admin0.00.10.30.0-0.2-0.5-0.10.1-0.20.1-0.10.2
Delta time to tail flick, vehicle, before/after SA0.50.51.40.91.2-0.4-1.00.7-0.50.7-0.4-0.2
Delta time to tail flick, test, before/after SA2.73.46.31.20.5-2.3-0.91.7-2.11.9-2.32.5
Tibia length0.61.52.80.80.9-1.5-0.51.1-1.41.2-1.51.7
Ambulatory time before self-admin0.10.31.1-0.10.20.6-0.0-0.40.5-0.40.7-1.0
Ambulatory time after self-admin0.91.42.2-1.1-0.81.50.8-1.21.3-1.31.3-1.1
Bone: tissue strength0.20.30.4-0.4-0.30.40.3-0.50.6-0.60.6-0.6
Total heroin consumption3.54.15.62.42.2-2.0-2.42.2-1.92.1-1.70.5
Bone: trabecular number0.61.14.90.40.81.2-0.8-0.10.7-0.41.2-2.2
Bone: trabecular spacing0.20.31.0-0.4-0.6-0.60.6-0.1-0.1-0.0-0.41.0
Bone: trabecular thickness1.11.63.0-0.8-0.51.70.5-1.11.4-1.21.6-1.7
Bone: trabecular tissue density2.84.810.1-2.9-3.11.23.2-2.31.7-2.01.01.0
Water consumed over 24 hours0.30.51.10.91.0-0.7-1.00.7-0.50.6-0.2-0.5
Number of responses in last shaping day0.10.20.30.40.4-0.5-0.40.4-0.40.4-0.50.4