Hub : Genes

Crk

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Crk 0.17 0.09 4.3e-07 0.11 0.11 0.12 0.12 1.3e-06 2.2e-06 8.4e-07 1.1e-06
2 PL gene expression Crk 0.22 0.1 0.0e+00 0.21 0.2 0.2 0.21 4.3e-22 9.9e-22 9.0e-22 2.8e-22
3 OFC gene expression Crk 0.29 0.13 1.1e-05 0.2 0.24 0.23 0.21 1.6e-05 2.2e-06 3.3e-06 1.2e-05
4 LHb gene expression Crk 0.36 0.15 1.5e-06 0.22 0.27 0.23 0.2 7.1e-06 3.5e-07 4.1e-06 1.5e-05
5 Brain gene expression Crk 0.33 0.13 0.0e+00 0.25 0.25 0.25 0.26 7.2e-23 2.5e-23 1.3e-23 2.6e-24
6 NAcc mRNA stability Crk 0.23 0.1 0.0e+00 0.21 0.22 0.22 0.22 1.3e-31 9.4e-33 1.1e-32 2.7e-32
7 BLA mRNA stability Crk 0.32 0.08 0.0e+00 0.28 0.28 0.28 0.28 2.1e-15 1.9e-15 3.7e-15 2.7e-15
8 Brain mRNA stability Crk 0.36 0.11 0.0e+00 0.26 0.27 0.27 0.27 7.5e-24 8.5e-25 4.7e-25 3.7e-25
9 IC mRNA stability Crk 0.39 0.15 8.2e-12 0.3 0.17 0.26 0.1 3.2e-13 1.5e-07 1.5e-11 8.2e-05
10 RMTg gene expression Crk 0.18 0.12 4.0e-03 0.11 0.1 0.09 0.12 8.0e-04 1.5e-03 1.8e-03 4.9e-04
11 IL mRNA stability Crk 0.2 0.12 1.5e-03 0.11 0.03 0.07 -0.01 1.5e-03 5.6e-02 8.5e-03 5.1e-01
12 Liver mRNA stability Crk 0.09 0.06 4.3e-06 0.04 0.03 0.03 0.03 6.1e-05 3.8e-04 3.4e-04 3.7e-04
13 pVTA gene expression Crk 0.18 0.1 2.6e-12 0.17 0.12 0.16 0.14 7.8e-14 3.4e-10 1.7e-12 4.5e-11
14 Adipose mRNA stability Crk 0.17 0.08 0.0e+00 0.13 0.14 0.13 0.14 8.0e-14 5.8e-15 1.1e-14 3.8e-15
15 OFC mRNA stability Crk 0.17 0.11 9.9e-04 0.06 0.14 0.1 0.12 1.5e-02 4.3e-04 2.2e-03 1.1e-03
16 IL gene expression Crk 0.2 0.13 9.2e-04 0.02 0.03 0.03 0.02 1.1e-01 6.7e-02 7.2e-02 1.1e-01
17 PL mRNA stability Crk 0.28 0.1 0.0e+00 0.28 0.28 0.28 0.29 9.7e-31 3.5e-31 4.3e-31 1.8e-31
18 Liver gene expression Crk 0.13 0.07 0.0e+00 0.09 0.13 0.12 0.12 5.9e-10 7.3e-14 1.2e-13 1.2e-13
19 NAcc gene expression Crk 0.51 0.17 0.0e+00 0.23 0.23 0.23 0.23 9.4e-34 7.7e-35 8.9e-34 6.8e-34
20 pVTA mRNA stability Crk 0.25 0.12 0.0e+00 0.26 0.2 0.24 0.11 3.0e-21 1.2e-15 1.5e-19 2.1e-09
21 IC gene expression Crk 0.35 0.15 3.6e-11 0.28 0.12 0.28 0.06 5.1e-12 1.2e-05 2.2e-12 2.2e-03
22 Brain intron excision ratio chr10_61040004_61051412 0.03 0.03 9.0e-03 0.01 0 0 0 5.3e-02 1.7e-01 2.3e-01 1.1e-01
23 LHb mRNA stability Crk 0.29 0.14 9.6e-06 0.19 0.13 0.18 0.16 2.9e-05 5.8e-04 5.1e-05 1.7e-04
24 NAcc intron excision ratio chr10_61040174_61051412 0.01 0.01 6.4e-03 0.01 0.01 0 0 1.3e-02 2.6e-02 1.4e-01 4.8e-02
25 Adipose gene expression Crk 0.02 0.02 6.9e-03 0.01 0.01 0 0.01 2.1e-02 2.8e-02 1.0e-01 3.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density4.68.09.83.13.03.13.13.03.02.93.03.02.92.92.92.93.03.03.02.82.92.82.62.52.52.5-2.02.1
Area under the delay curve1.61.83.0-1.2-1.4-1.5-1.5-1.3-1.5-1.5-1.3-1.3-1.2-1.2-1.2-1.2-1.5-1.4-1.4-1.4-1.3-1.6-1.6-0.7-1.7-1.61.0-1.0
BMI with tail1.13.75.22.32.12.02.12.01.92.02.02.12.12.12.12.11.91.91.92.21.91.72.21.41.61.7-1.40.8
BMI without tail0.82.67.22.01.21.61.71.11.21.21.01.11.21.21.21.21.62.12.21.22.31.01.22.70.70.7-2.52.4
Body weight1.04.318.82.51.21.92.11.01.31.20.91.01.11.11.11.12.02.93.10.83.20.70.74.30.20.2-4.03.6
Weight adjusted by age0.40.61.00.71.00.80.81.00.80.91.01.01.01.01.01.00.70.50.50.90.50.80.90.10.60.6-0.00.0
Bone surface4.07.39.83.03.12.92.93.12.82.93.13.13.03.03.03.02.82.72.62.92.52.52.52.12.02.0-1.61.5
Bone volume4.17.49.73.13.12.92.93.12.82.93.13.13.13.13.13.12.82.72.72.92.52.52.62.22.02.0-1.61.5
Breakpoint value in progressive ratio session0.81.02.51.10.81.01.10.70.80.80.80.70.80.80.80.81.11.31.40.71.40.60.61.60.70.5-1.51.5
Number of licking bursts0.50.92.6-1.0-0.8-0.9-1.0-0.8-1.0-0.9-0.8-0.8-0.7-0.7-0.7-0.7-0.9-0.8-0.8-1.0-0.9-1.3-1.4-0.3-1.5-1.60.6-0.7
Context. condit. distance diff. score1.51.82.51.41.21.51.51.21.51.41.21.21.21.21.21.21.41.51.51.31.41.61.31.11.51.5-1.20.8
Locomotion velocity, session 13.13.35.02.11.62.02.01.61.81.81.61.51.71.71.71.72.02.22.21.52.21.71.32.21.61.6-2.01.9
Locomotion distance, session 10.70.81.41.01.21.01.01.20.91.01.21.21.11.11.11.10.90.80.80.70.70.70.30.80.50.5-0.30.4
Locomotion velocity, session 20.91.01.21.11.11.11.11.11.11.11.11.11.11.11.11.11.11.01.00.81.01.00.61.00.90.9-0.70.7
Locomotion distance, session 21.72.43.61.71.91.71.71.91.61.71.91.91.71.71.71.71.71.51.41.41.41.41.11.21.31.3-0.81.1
Locomotion velocity, session 35.66.49.5-2.5-2.6-2.7-2.6-2.6-2.8-2.7-2.6-2.6-2.5-2.5-2.5-2.5-2.7-2.4-2.3-2.8-2.2-3.0-3.1-1.1-2.9-2.91.2-1.3
Locomotion distance, session 30.10.10.2-0.10.2-0.2-0.10.2-0.20.00.20.20.20.20.20.2-0.1-0.4-0.3-0.1-0.3-0.3-0.5-0.2-0.2-0.10.5-0.5
Stereotopy head waving bouts, day 30.10.10.50.1-0.4-0.1-0.1-0.4-0.3-0.3-0.4-0.5-0.2-0.2-0.2-0.2-0.10.10.2-0.50.2-0.5-0.60.6-0.4-0.4-0.60.7
Stereotopy head waving duration, day 30.30.41.2-0.4-0.5-0.6-0.6-0.4-0.6-0.5-0.4-0.5-0.1-0.1-0.1-0.1-0.7-0.5-0.6-0.7-0.6-0.9-1.0-0.2-1.1-1.10.5-0.7
Locomotion velocity, session 71.21.31.81.21.31.11.21.31.21.31.31.31.21.21.21.21.20.90.91.20.91.21.20.31.31.3-0.30.3
Locomotion distance, session 71.92.43.31.51.71.61.61.71.61.71.71.71.71.71.71.71.61.31.31.81.31.71.80.61.81.8-0.60.6
Stereotopy head waving bouts, day 70.80.92.21.30.91.01.00.90.80.90.90.81.21.21.21.20.91.11.10.51.10.4-0.21.50.10.1-1.10.9
Stereotopy head waving duration, day 71.21.42.51.61.31.21.21.31.11.21.31.21.61.61.61.61.21.31.30.81.20.50.11.50.10.2-1.00.9
Locomotion velocity, session 80.50.60.90.61.00.80.81.00.90.91.01.00.90.90.90.90.70.60.60.80.51.00.60.20.70.7-0.1-0.1
Locomotion distance, session 82.23.24.32.01.92.02.01.91.91.81.91.91.71.71.71.71.92.12.11.52.01.71.22.01.41.4-1.71.4
Degree of sensitization distance1.31.32.71.20.91.21.20.91.21.00.90.90.80.80.80.81.31.41.31.21.31.31.60.91.31.3-1.21.3
Degree of sensitization stereotypy1.21.32.41.51.11.21.21.11.11.11.11.01.31.31.31.31.21.31.30.71.30.70.21.60.40.3-1.21.1
Conditioned locomotion0.20.21.1-0.5-0.5-0.5-0.6-0.4-0.4-0.4-0.4-0.4-0.3-0.3-0.3-0.3-0.5-0.6-0.7-0.0-0.7-0.30.1-1.1-0.0-0.00.8-0.6
Cocaine response after cond. corrected0.10.10.50.1-0.10.30.3-0.10.20.1-0.1-0.1-0.1-0.1-0.1-0.10.20.50.50.00.50.40.20.40.50.5-0.70.7
Cocaine response after cond. not corrected0.30.30.80.50.30.60.60.30.50.40.30.30.30.30.30.30.50.80.80.40.90.60.40.90.50.5-0.90.9
Cocaine response before conditioning1.01.11.71.21.31.11.21.21.01.11.21.31.31.31.31.31.01.11.11.11.10.80.81.20.30.4-0.70.5
Saline control response0.30.51.00.61.00.60.61.00.60.71.01.01.01.01.01.00.50.40.40.60.30.30.20.5-0.2-0.20.1-0.2
Bone: connectivity density6.710.512.93.63.63.53.53.53.43.53.53.63.43.43.43.43.53.33.33.23.13.22.92.52.82.9-2.12.3
Bone: cortical apparent density0.30.41.6-0.7-0.3-0.5-0.6-0.3-0.3-0.3-0.2-0.3-0.2-0.2-0.2-0.2-0.5-0.8-0.9-0.3-1.0-0.0-0.4-1.30.10.11.2-1.1
Bone: cortical area1.93.04.0-2.0-1.9-1.9-1.8-1.8-1.9-1.9-1.8-1.8-2.0-2.0-2.0-2.0-1.8-1.8-1.7-1.7-1.6-1.7-1.5-1.2-1.5-1.40.9-0.9
Bone: cortical porosity0.10.10.30.50.20.40.40.20.30.30.30.20.30.30.30.30.30.40.40.20.50.40.30.50.20.2-0.40.2
Bone: cortical porosity0.00.00.1-0.0-0.2-0.1-0.1-0.2-0.2-0.2-0.2-0.2-0.1-0.1-0.1-0.1-0.2-0.0-0.0-0.20.0-0.1-0.10.2-0.3-0.3-0.1-0.1
Bone: cortical thickness6.310.513.9-3.4-3.6-3.4-3.4-3.6-3.5-3.5-3.6-3.6-3.7-3.7-3.7-3.7-3.3-3.0-2.9-3.6-2.7-3.3-3.5-1.7-2.9-2.91.4-1.4
Bone: cortical thickness1.51.73.1-1.2-1.5-1.3-1.2-1.5-1.4-1.5-1.6-1.5-1.7-1.7-1.7-1.7-1.3-0.9-0.8-1.6-0.6-1.3-1.5-0.0-1.0-1.1-0.1-0.1
Bone: cortical tissue density0.20.21.1-0.5-0.2-0.3-0.4-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.3-0.6-0.7-0.1-0.80.1-0.2-1.10.30.21.0-0.8
Condit. Reinf. active minus inactive responses0.30.40.7-0.3-0.8-0.6-0.6-0.8-0.7-0.7-0.8-0.9-0.7-0.7-0.7-0.7-0.4-0.4-0.3-0.6-0.2-0.9-0.60.2-0.8-0.7-0.20.2
Condit. Reinf. active-inactive response ratio2.83.04.9-1.4-2.2-1.7-1.6-2.2-2.0-2.0-2.2-2.2-2.1-2.1-2.1-2.1-1.3-1.1-1.0-1.9-0.8-2.1-1.80.2-1.9-1.9-0.30.5
Condit. Reinf. active responses0.20.30.70.70.50.50.50.40.50.50.40.40.50.50.50.50.60.50.50.70.50.40.80.20.50.5-0.30.3
Condit. Reinf. inactive responses3.54.37.21.82.52.01.92.52.32.32.52.52.52.52.52.51.71.41.22.50.92.32.7-0.42.22.10.3-0.4
Incentive salience index mean0.20.20.5-0.1-0.6-0.3-0.3-0.7-0.5-0.5-0.7-0.7-0.6-0.6-0.6-0.6-0.1-0.10.0-0.50.2-0.5-0.50.5-0.3-0.2-0.60.4
Condit. Reinf. lever presses0.40.52.20.80.20.60.70.10.40.40.10.10.10.10.10.10.70.91.10.21.20.50.31.30.80.8-1.51.0
Condit. Reinf. active minus inactive responses0.40.50.90.80.80.70.80.70.80.80.80.80.80.80.80.80.80.70.61.00.60.70.80.50.50.5-0.40.5
Condit. Reinf. active-inactive response ratio0.10.10.2-0.2-0.5-0.2-0.2-0.5-0.2-0.3-0.5-0.5-0.4-0.4-0.4-0.4-0.1-0.00.0-0.00.1-0.10.00.2-0.1-0.1-0.40.4
Condit. Reinf. active responses0.91.32.61.21.41.11.11.41.11.21.41.41.61.61.61.61.00.80.71.40.60.90.90.50.30.40.0-0.0
Condit. Reinf. inactive responses2.22.86.31.72.31.51.42.31.61.92.32.32.52.52.52.51.30.80.71.80.51.21.20.10.40.50.7-0.8
Condit. Reinf. lever presses0.40.52.8-0.40.1-0.5-0.50.2-0.3-0.20.20.20.50.50.50.5-0.7-0.9-0.90.3-1.0-0.5-0.1-1.1-1.1-1.01.4-1.7
Condit. Reinf. lever reinforcers received0.81.12.61.11.40.90.91.31.01.11.41.41.61.61.61.60.90.60.61.30.40.70.80.30.10.20.2-0.2
Conditioned reinforcement - actives1.42.53.51.61.71.61.61.71.81.81.71.81.71.71.71.71.51.31.31.91.21.91.90.41.61.5-0.40.4
Conditioned reinforcement - inactives0.30.40.60.50.60.70.70.70.70.70.70.70.70.70.70.70.70.60.50.70.50.70.80.40.70.8-0.20.1
Conditioned locomotion0.30.40.9-0.5-0.3-0.7-0.6-0.3-0.6-0.4-0.4-0.2-0.1-0.1-0.1-0.1-0.6-0.9-0.8-0.3-0.9-0.6-0.5-0.8-0.8-0.70.9-0.9
Patch foraging indifference point 0 sec0.20.30.60.60.70.50.60.70.60.60.70.70.60.60.60.60.50.40.40.70.40.60.80.20.50.5-0.1-0.2
Patch foraging indifference point AUC0.10.21.0-0.4-0.1-0.2-0.3-0.1-0.1-0.0-0.0-0.10.00.00.00.0-0.2-0.5-0.6-0.1-0.70.0-0.1-0.80.30.31.0-0.8
Delay disc. indifference point, 0s delay0.10.10.30.50.10.20.20.20.20.30.20.30.50.50.50.50.30.30.30.20.2-0.2-0.00.5-0.5-0.5-0.20.5
Delay disc. indifference point, 16s delay1.51.73.1-1.2-1.2-1.4-1.4-1.2-1.4-1.4-1.2-1.1-1.1-1.1-1.1-1.1-1.5-1.3-1.3-1.4-1.3-1.5-1.8-0.7-1.7-1.61.0-1.0
Delay disc. indifference point, 2s delay1.11.22.0-0.9-1.0-1.2-1.2-1.0-1.2-1.2-1.0-0.9-1.0-1.0-1.0-1.0-1.3-1.1-1.1-1.1-1.1-1.2-1.2-0.5-1.4-1.30.9-0.9
Delay disc. indifference point, 24s delay0.30.30.5-0.6-0.6-0.6-0.6-0.5-0.6-0.6-0.5-0.7-0.5-0.5-0.5-0.5-0.7-0.6-0.6-0.5-0.6-0.5-0.7-0.5-0.6-0.70.6-0.6
Delay disc. indifference point, 4s delay1.11.11.9-1.0-1.4-1.1-1.1-1.3-1.1-1.2-1.2-1.1-1.0-1.0-1.0-1.0-1.1-0.9-0.9-1.2-0.8-1.2-1.3-0.0-1.3-1.30.4-0.4
Delay disc. indifference point, 8s delay0.91.01.6-0.9-1.1-1.1-1.1-1.0-1.1-1.1-1.0-1.2-1.0-1.0-1.0-1.0-1.2-1.0-0.9-1.1-0.9-1.1-1.1-0.5-1.3-1.20.6-0.8
Indifference point function ln k0.51.01.31.21.01.11.11.11.01.01.01.01.01.01.01.01.01.01.00.91.01.10.80.90.80.8-0.80.5
Indifference point function log k0.51.01.31.21.01.11.11.11.01.01.01.01.01.01.01.01.01.01.00.91.01.10.80.90.80.8-0.80.5
Patch foraging total patch changes 0 sec0.20.40.80.60.80.60.70.80.70.70.80.80.80.80.80.80.60.40.50.80.50.70.90.20.60.6-0.1-0.2
Patch foraging total patch changes 12 sec0.30.50.7-0.7-0.8-0.7-0.7-0.8-0.8-0.7-0.8-0.8-0.8-0.8-0.8-0.8-0.7-0.6-0.6-0.7-0.5-0.8-0.5-0.2-0.6-0.50.3-0.3
Patch foraging total patch changes 18 sec0.61.02.1-0.8-1.1-1.0-1.0-1.1-1.1-1.1-1.0-1.1-0.9-0.9-0.9-0.9-1.0-0.8-0.7-1.3-0.7-1.3-1.40.1-1.3-1.30.3-0.3
Patch foraging total patch changes 24 sec0.40.71.1-0.8-0.8-0.9-0.9-0.8-0.9-0.8-0.7-0.7-0.8-0.8-0.8-0.8-0.8-0.9-0.9-0.9-0.8-0.9-1.0-0.6-0.8-0.80.8-0.6
Patch foraging total patch changes 6 sec0.10.21.7-0.30.1-0.3-0.30.2-0.1-0.00.20.20.20.20.20.2-0.5-0.6-0.60.1-0.7-0.20.2-0.8-0.4-0.31.0-1.3
Patch foraging time to switch 0 sec0.91.83.3-1.0-1.6-1.2-1.2-1.7-1.5-1.6-1.6-1.7-1.5-1.5-1.5-1.5-1.2-0.7-0.6-1.4-0.5-1.5-1.20.4-1.8-1.8-0.50.4
Patch foraging water rate 0 sec0.30.51.10.40.90.50.41.10.70.81.01.00.90.90.90.90.50.0-0.00.8-0.20.70.6-0.70.70.70.7-0.7
Patch foraging water rate 12 sec0.00.00.20.10.20.10.10.20.10.00.20.10.10.10.10.1-0.10.10.1-0.10.10.0-0.40.3-0.2-0.2-0.1-0.1
Patch foraging water rate 18 sec2.23.45.42.02.22.02.02.32.12.12.22.32.22.22.22.21.81.81.71.81.61.81.41.11.31.2-0.90.7
Patch foraging water rate 24 sec0.20.30.60.40.60.40.40.80.50.60.70.70.80.80.80.80.20.20.10.40.10.40.0-0.10.20.20.2-0.6
Patch foraging water rate 6 sec0.20.31.0-0.6-0.3-0.5-0.5-0.2-0.4-0.3-0.2-0.3-0.2-0.2-0.2-0.2-0.5-0.8-0.8-0.4-0.8-0.3-0.7-0.8-0.2-0.21.0-0.8
Seeking ratio, delayed vs. immediate footshock1.11.43.2-1.1-0.7-1.3-1.3-0.7-1.2-1.1-0.6-0.7-0.5-0.5-0.5-0.5-1.4-1.5-1.5-0.8-1.6-1.3-0.9-1.3-1.8-1.71.5-1.5
Distance traveled before self-admin3.64.86.3-2.1-2.0-2.4-2.4-2.0-2.3-2.3-2.1-2.0-2.1-2.1-2.1-2.1-2.4-2.4-2.4-2.2-2.4-2.4-2.1-1.8-2.5-2.41.9-1.6
Distance traveled after self-admin0.40.50.8-0.7-0.9-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.7-0.7-0.7-0.7-0.7-0.8-0.8-0.8-0.7-0.9-0.6-0.5-0.9-0.80.5-0.3
Extensor digitorum longus weight5.621.828.75.15.45.04.95.35.15.35.35.35.35.35.35.35.04.34.14.83.94.74.32.44.44.5-2.02.2
Bone: elastic displacement0.50.51.7-0.8-0.6-0.7-0.8-0.5-0.6-0.6-0.5-0.5-0.4-0.4-0.4-0.4-0.8-0.9-1.0-0.6-1.0-0.4-0.9-1.1-0.3-0.41.2-1.3
Bone: elastic work5.26.78.6-2.8-2.8-2.8-2.7-2.8-2.9-2.8-2.8-2.7-2.8-2.8-2.8-2.8-2.7-2.6-2.5-2.9-2.3-2.7-2.9-1.5-2.3-2.31.5-1.7
Bone: endosteal estimation0.20.51.00.50.80.60.60.80.60.70.80.81.01.01.01.00.50.50.41.00.40.51.00.30.30.4-0.1-0.0
Bone: endosteal perimeter1.02.14.71.21.81.41.31.71.61.61.81.71.81.81.81.81.30.90.92.00.71.52.2-0.11.31.40.10.0
Epididymis fat weight7.224.833.85.74.95.55.54.95.14.94.94.85.05.05.05.05.35.85.84.75.64.54.25.43.43.4-4.94.6
Delta time in closed arm before/after self-admin0.60.61.6-0.9-0.5-0.7-0.8-0.6-0.6-0.5-0.4-0.4-0.3-0.3-0.3-0.3-0.7-1.0-1.1-0.5-1.2-0.6-0.7-1.2-0.8-0.81.3-1.0
Delta time in open arm before/after self-admin0.90.91.81.40.91.01.00.90.80.80.80.80.80.80.80.80.91.11.20.71.20.80.71.30.70.8-1.20.7
Diff in mean of infusions in LGA sessions1.21.52.71.30.91.21.30.81.11.10.90.81.01.01.01.01.31.41.41.01.51.31.31.31.61.3-1.51.4
Delay discount exponential model param1.41.62.31.11.41.41.31.31.41.41.21.31.11.11.11.11.41.31.21.31.21.41.40.61.51.4-0.90.9
Extinction: sum of active levers before priming2.73.04.81.71.91.81.81.91.91.91.91.82.02.02.02.01.81.51.41.81.41.91.60.82.22.0-0.70.4
Active lever presses in extinction session 62.62.63.11.71.71.71.71.71.71.71.71.81.81.81.81.81.71.51.51.61.51.71.51.01.81.6-0.90.8
Bone: final force1.11.73.0-1.0-1.4-1.3-1.1-1.5-1.6-1.5-1.5-1.5-1.6-1.6-1.6-1.6-1.1-0.9-0.6-1.5-0.4-1.7-1.50.5-1.7-1.6-0.50.3
Bone: final moment0.91.42.4-0.9-1.3-1.2-1.0-1.3-1.4-1.3-1.3-1.3-1.4-1.4-1.4-1.4-1.1-0.9-0.6-1.3-0.4-1.5-1.30.4-1.5-1.4-0.30.1
Food consumed during 24 hour testing period0.30.40.80.70.60.60.70.50.60.70.50.50.70.70.70.70.70.60.60.60.70.80.70.50.90.9-0.50.3
Glucose4.16.48.2-2.9-2.6-2.8-2.8-2.6-2.7-2.7-2.5-2.6-2.5-2.5-2.5-2.5-2.7-2.7-2.7-2.6-2.7-2.5-2.6-2.0-2.3-2.32.1-1.7
Heart weight1.21.95.51.71.11.41.51.11.21.21.01.10.90.90.90.91.71.71.80.91.90.90.92.00.90.9-1.92.3
Delay discount hyperbolic model param1.71.92.71.31.51.51.51.41.51.51.41.41.31.31.31.31.51.31.31.51.31.61.50.61.61.5-0.90.9
Intermittent access intake day 1-15 change0.10.31.9-0.70.0-0.3-0.40.1-0.10.00.10.20.00.00.00.0-0.2-0.7-0.80.1-0.90.00.3-1.40.10.21.3-1.1
Intermittent access intake escalation0.20.32.0-0.60.1-0.3-0.30.2-0.10.10.10.20.10.10.10.1-0.2-0.7-0.80.2-0.90.10.3-1.40.20.31.3-1.1
Intermittent access intake escalation 20.40.42.5-0.9-0.1-0.5-0.6-0.1-0.2-0.2-0.1-0.0-0.2-0.2-0.2-0.2-0.5-0.9-1.00.0-1.1-0.10.2-1.60.10.11.4-1.3
Intermitt. access day 1 inactive lever presses0.52.04.5-1.8-1.3-1.5-1.6-1.2-1.3-1.2-1.1-1.0-1.1-1.1-1.1-1.1-1.5-1.9-1.9-1.0-1.9-1.1-0.7-2.1-0.8-0.71.9-1.8
Intermitt. access day 15 inactive lever presses0.81.75.7-1.5-0.9-1.3-1.4-0.8-0.9-0.9-0.8-0.8-0.8-0.8-0.8-0.8-1.4-1.7-1.9-0.7-2.0-0.7-0.3-2.4-0.7-0.62.2-2.2
Intermitt. access escalation Index0.40.64.20.7-0.30.40.4-0.30.10.0-0.3-0.4-0.3-0.3-0.3-0.30.61.01.0-0.21.1-0.00.01.50.30.1-1.92.0
Intermittent access day 1 total infusions0.00.10.4-0.1-0.1-0.2-0.2-0.0-0.2-0.2-0.0-0.1-0.1-0.1-0.1-0.1-0.4-0.2-0.2-0.1-0.2-0.3-0.3-0.1-0.6-0.60.2-0.5
Intermittent access day 15 total infusions0.20.30.60.10.70.30.30.70.40.50.70.70.60.60.60.60.2-0.1-0.10.7-0.20.40.7-0.70.20.30.7-0.8
Intermittent access terminal intake (last 3 days)0.60.81.50.71.10.90.91.21.01.01.11.11.01.01.01.00.70.60.61.20.51.01.2-0.00.60.70.0-0.2
Intermittent access total infusions0.10.10.60.00.40.10.10.50.20.30.40.40.40.40.40.4-0.1-0.1-0.10.5-0.20.20.4-0.5-0.10.00.5-0.8
Intermittent access day 1 locomotion0.50.61.5-0.7-0.7-0.8-0.8-0.7-0.9-0.8-0.7-0.8-0.6-0.6-0.6-0.6-0.9-0.7-0.7-0.8-0.6-1.0-1.2-0.1-1.1-1.20.5-0.6
Intermittent access day 15 total locomotion0.20.30.7-0.6-0.5-0.6-0.6-0.3-0.5-0.4-0.3-0.3-0.3-0.3-0.3-0.3-0.5-0.7-0.7-0.5-0.8-0.6-0.5-0.7-0.8-0.60.9-0.7
Intermittent access total locomotion0.10.10.6-0.3-0.1-0.3-0.3-0.1-0.3-0.2-0.1-0.1-0.0-0.0-0.0-0.0-0.3-0.5-0.5-0.2-0.5-0.3-0.5-0.4-0.5-0.40.8-0.6
Intermittent access standard deviation0.40.83.1-0.30.80.20.10.80.50.70.80.80.80.80.80.80.0-0.5-0.70.9-0.80.70.7-1.70.70.91.8-1.7
Left kidney weight1.98.914.1-2.4-3.4-3.0-2.8-3.4-3.4-3.4-3.4-3.4-3.4-3.4-3.4-3.4-2.7-2.0-1.8-3.7-1.5-3.6-3.80.4-3.6-3.6-0.00.2
Right kidney weight1.57.011.4-2.0-3.0-2.5-2.3-3.1-2.9-3.0-3.2-3.1-3.1-3.1-3.1-3.1-2.3-1.5-1.2-3.4-1.0-3.2-3.41.0-3.2-3.2-0.70.8
Cocaine induced anxiety0.10.10.5-0.3-0.1-0.2-0.3-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.2-0.3-0.4-0.1-0.40.0-0.4-0.60.10.20.6-0.7
Post-drug Anxiety0.30.41.00.70.30.70.70.30.60.50.30.30.20.20.20.20.60.90.90.20.90.7-0.01.00.70.7-1.00.7
Baseline Anxiety0.91.02.41.10.71.11.10.61.00.90.60.70.60.60.60.61.11.41.40.61.41.00.71.50.90.8-1.51.4
Tail length0.62.213.61.1-0.40.60.7-0.5-0.0-0.3-0.5-0.6-0.4-0.4-0.4-0.40.81.71.9-0.72.1-0.5-0.83.7-0.9-1.0-3.33.6
Length with tail0.62.613.90.6-0.90.20.3-1.0-0.5-0.8-1.1-1.1-1.0-1.0-1.0-1.00.41.51.6-1.41.9-0.9-1.63.7-1.3-1.4-3.43.6
Length without tail0.30.85.50.90.20.60.70.10.30.10.00.10.00.00.00.00.51.31.3-0.31.4-0.1-0.52.4-0.6-0.7-2.01.7
Times rat made contact with spout1.41.72.7-1.1-1.6-1.3-1.2-1.6-1.5-1.5-1.6-1.6-1.4-1.4-1.4-1.4-1.2-1.0-0.8-1.6-0.6-1.5-1.60.1-1.3-1.3-0.10.1
Lifetime Intake0.10.10.70.00.40.10.10.40.20.30.40.30.30.30.30.3-0.1-0.1-0.10.4-0.20.30.3-0.50.10.10.6-0.8
Liver weight, left2.23.715.82.10.51.71.80.51.20.90.40.40.50.50.50.51.82.82.90.63.11.00.74.00.90.9-3.93.8
Liver weight, right1.93.312.42.10.81.71.80.71.31.10.60.70.80.80.80.81.82.62.70.92.81.00.93.50.90.8-3.53.2
Locomotor activity0.00.10.10.30.30.30.30.30.20.20.30.30.30.30.30.30.30.30.30.20.20.10.10.4-0.1-0.1-0.10.2
Locomotor testing distance0.00.10.10.30.20.20.20.30.20.10.30.30.30.30.30.30.20.20.2-0.00.10.0-0.00.3-0.3-0.3-0.10.2
Locomotor testing rearing0.30.61.40.71.00.70.71.00.80.81.11.11.21.21.21.20.60.50.40.80.20.70.60.10.30.20.2-0.1
Locomotion in novel chamber1.31.77.7-1.1-0.3-1.1-1.2-0.2-0.7-0.6-0.3-0.2-0.3-0.3-0.3-0.3-1.3-1.9-2.0-0.4-2.1-0.5-0.3-2.7-0.5-0.52.8-2.8
Locomotion in novel chamber post-restriction0.30.40.70.60.80.50.50.80.70.70.80.80.80.80.80.80.50.20.20.70.20.70.8-0.20.70.80.4-0.5
Fecal boli incidents, locomotor time 10.00.00.10.20.10.00.10.1-0.1-0.10.10.0-0.2-0.2-0.2-0.20.10.10.2-0.20.2-0.1-0.20.40.30.3-0.20.3
Change in fecal boli incidents, locomotor task0.50.41.0-0.8-0.9-0.6-0.6-1.0-0.6-0.7-1.0-0.9-0.9-0.9-0.9-0.9-0.6-0.5-0.4-0.5-0.3-0.4-0.4-0.3-0.4-0.50.00.0
Time >=10cm from walls, locomotor time 10.30.31.40.50.50.40.50.40.50.60.40.60.40.40.40.40.50.30.40.60.40.60.7-0.01.11.2-0.2-0.0
Bouts of movement, locomotor time 10.20.21.20.40.10.30.30.10.30.40.10.10.20.20.20.20.30.30.30.30.30.60.8-0.11.01.1-0.2-0.1
Total resting periods, locomotor time 10.30.31.90.30.20.40.30.20.50.40.20.20.30.30.30.30.40.20.20.50.20.81.1-0.31.31.4-0.1-0.3
Rest time, locomotor task time 10.20.31.5-0.6-0.5-0.4-0.4-0.3-0.2-0.2-0.3-0.3-0.2-0.2-0.2-0.2-0.4-0.6-0.60.1-0.60.10.5-1.20.70.60.8-1.2
Distance moved, locomotor task time 10.00.10.20.40.40.30.30.30.30.30.30.30.30.30.30.30.30.20.20.20.20.2-0.00.4-0.1-0.0-0.10.3
Vertical activity count, locomotor time 10.30.81.51.21.10.90.91.00.91.01.01.11.11.11.11.10.90.80.80.90.80.70.70.70.10.2-0.50.7
Time >=10cm from walls, locomotor time 20.40.71.0-1.0-1.0-1.0-0.8-1.0-1.0-0.9-1.0-0.8-0.9-0.9-0.9-0.9-0.8-1.0-0.8-0.6-0.6-0.9-0.4-0.6-0.3-0.40.4-0.5
Bouts of movement, locomotor time 20.00.10.2-0.4-0.2-0.3-0.3-0.4-0.2-0.3-0.4-0.4-0.3-0.3-0.3-0.3-0.4-0.2-0.2-0.2-0.2-0.20.1-0.2-0.1-0.20.0-0.3
Total resting periods, locomotor time 20.00.00.1-0.00.10.10.10.00.10.10.0-0.00.10.10.10.1-0.00.20.10.10.10.20.30.00.30.1-0.2-0.2
Rest time, locomotor task time 20.20.30.80.30.30.60.50.50.70.60.50.50.40.40.40.40.40.50.40.60.30.90.8-0.20.90.8-0.0-0.2
Distance moved, locomotor task time 20.20.20.9-0.3-0.3-0.5-0.5-0.3-0.4-0.3-0.3-0.1-0.0-0.0-0.0-0.0-0.5-0.7-0.7-0.2-0.7-0.5-0.4-0.5-0.7-0.60.9-1.0
Vertical activity count, locomotor time 20.30.40.8-0.4-0.7-0.7-0.7-0.7-0.8-0.7-0.6-0.6-0.5-0.5-0.5-0.5-0.6-0.6-0.6-0.6-0.6-0.9-0.5-0.2-0.8-0.80.4-0.2
Light reinforcement 10.00.11.00.20.20.00.00.2-0.0-0.00.20.20.30.30.30.3-0.10.10.00.1-0.0-0.3-0.10.4-1.0-1.00.0-0.1
Light reinforcement 22.53.98.3-1.8-2.0-2.0-2.0-2.0-2.2-2.2-2.0-2.1-2.0-2.0-2.0-2.0-1.9-1.7-1.6-2.1-1.5-2.4-2.2-0.5-2.9-2.90.6-0.4
Bone: marrow area0.20.41.00.50.80.60.60.80.60.70.80.70.90.90.90.90.50.50.41.00.40.51.00.30.40.4-0.1-0.0
Bone: maximum diameter0.10.20.9-0.20.40.00.10.40.20.30.40.30.30.30.30.30.1-0.3-0.30.7-0.30.40.9-0.80.40.50.7-0.6
Bone: maximum force1.22.13.3-1.3-1.6-1.5-1.3-1.6-1.7-1.6-1.6-1.6-1.7-1.7-1.7-1.7-1.3-1.1-0.9-1.6-0.7-1.8-1.60.2-1.7-1.6-0.20.1
Bone: maximum moment1.01.72.6-1.2-1.4-1.4-1.2-1.4-1.6-1.5-1.4-1.4-1.5-1.5-1.5-1.5-1.3-1.1-0.9-1.5-0.7-1.6-1.5-0.0-1.5-1.4-0.0-0.2
Mean time between licks in bursts0.10.31.50.3-0.10.20.3-0.10.0-0.0-0.1-0.0-0.2-0.2-0.2-0.20.30.60.7-0.50.7-0.2-0.61.2-0.2-0.2-1.11.2
Mean num. licks in bursts0.10.20.50.1-0.3-0.00.1-0.4-0.1-0.1-0.4-0.4-0.4-0.4-0.4-0.40.10.10.3-0.10.50.30.40.40.60.7-0.70.7
Cd content in liver1.01.12.10.51.11.10.91.21.31.21.21.31.21.21.21.21.00.70.51.20.31.41.1-0.41.41.30.40.1
Co content in liver0.10.10.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.5-0.5-0.5-0.5-0.3-0.3-0.3-0.5-0.2-0.2-0.4-0.3-0.1-0.10.2-0.3
Cu content in liver0.81.01.4-1.2-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.0-1.0-1.0-1.0-1.0-1.1-1.0-0.8-1.0-0.9-0.7-0.9-0.8-0.80.7-0.5
Fe content in liver0.10.21.00.2-0.00.20.2-0.20.0-0.1-0.2-0.2-0.2-0.2-0.2-0.20.20.50.60.00.6-0.00.11.0-0.1-0.2-1.00.9
K content in liver0.60.51.6-0.1-0.6-0.5-0.3-0.7-0.7-0.7-0.7-0.7-0.8-0.8-0.8-0.8-0.2-0.00.1-0.80.3-1.0-0.71.0-1.2-1.1-0.91.3
Mg content in liver0.10.10.40.30.50.30.30.40.20.30.40.40.40.40.40.40.40.10.20.40.20.10.6-0.00.00.10.00.3
Mn content in liver0.70.71.60.61.00.80.81.00.90.91.01.01.01.01.01.00.70.50.41.10.41.01.2-0.21.01.00.2-0.2
Na content in liver3.03.24.4-1.5-2.0-1.9-1.9-2.1-2.0-2.0-2.0-2.1-1.9-1.9-1.9-1.9-1.9-1.6-1.5-2.1-1.4-2.1-1.9-0.6-2.0-1.90.6-0.8
Rb content in liver4.04.67.82.12.42.22.22.42.32.32.42.52.42.42.42.42.31.81.72.51.62.32.80.72.02.1-0.71.1
Se content in liver0.60.71.2-1.1-0.9-0.9-0.8-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.8-0.7-0.9-0.7-0.9-0.9-0.4-0.7-0.70.4-0.5
Sr content in liver1.81.52.51.11.31.31.21.31.41.41.31.31.31.31.31.31.11.00.91.50.81.61.60.11.51.5-0.2-0.1
Zn content in liver0.20.30.90.30.20.50.50.10.50.40.10.10.10.10.10.10.50.70.70.20.80.60.40.61.00.9-0.80.7
Bone: minimum diameter0.81.52.3-1.3-1.4-1.3-1.2-1.4-1.3-1.4-1.4-1.4-1.5-1.5-1.5-1.5-1.2-0.9-0.9-1.2-0.8-1.3-1.1-0.2-1.3-1.30.1-0.1
Time in familiar zone, hab. session 11.51.42.50.81.51.11.01.51.31.31.51.61.31.31.31.30.90.50.41.30.31.51.2-0.61.51.50.5-0.6
Time in novel zone, hab. session 11.31.32.4-0.9-1.5-1.1-1.0-1.5-1.2-1.3-1.5-1.6-1.2-1.2-1.2-1.2-0.9-0.6-0.5-1.3-0.4-1.3-1.30.5-1.4-1.4-0.40.4
Total zone transitions, hab. session 11.42.04.21.32.01.31.32.01.41.52.12.02.02.02.02.01.20.90.81.60.50.91.00.50.20.20.30.0
Total locomotion distance, hab. session 10.50.71.40.91.10.90.81.20.90.91.21.21.11.11.11.10.80.80.70.70.50.50.40.70.10.1-0.10.3
Locomotion velocity, hab. session 10.60.81.70.91.30.90.91.31.01.01.31.31.21.21.21.20.80.70.60.90.50.60.60.50.30.20.00.1
Time in familiar zone, hab. session 21.81.93.11.41.71.51.41.81.51.61.81.81.71.71.71.71.31.21.11.20.91.20.80.81.11.0-0.30.1
Time in novel zone, hab. session 24.64.77.1-2.3-2.6-2.3-2.2-2.6-2.4-2.5-2.6-2.7-2.5-2.5-2.5-2.5-2.1-2.0-1.8-2.1-1.6-2.1-1.8-1.1-2.0-1.90.6-0.3
Total zone transitions, hab. session 20.81.11.71.31.31.11.11.31.01.01.31.31.31.31.31.31.01.01.00.80.90.50.31.2-0.1-0.1-0.60.7
Total locomotion distance, hab. session 20.10.10.60.40.40.30.30.30.20.20.30.30.20.20.20.20.30.40.40.00.3-0.1-0.10.8-0.3-0.4-0.30.4
Locomotion velocity, hab. session 20.00.10.40.30.30.20.20.20.10.20.20.30.10.10.10.10.20.30.30.00.3-0.1-0.10.7-0.2-0.3-0.30.3
Novel to familiar place preference ratio0.20.21.3-0.30.0-0.2-0.20.0-0.00.00.00.1-0.2-0.2-0.2-0.2-0.2-0.5-0.40.4-0.40.20.8-1.10.30.40.6-0.7
Novelty place preference0.10.10.5-0.20.0-0.1-0.10.00.00.0-0.00.0-0.2-0.2-0.2-0.2-0.1-0.2-0.20.3-0.20.30.7-0.70.40.50.3-0.3
Time in novel zone, NPP test0.10.10.80.10.30.20.20.20.20.20.20.30.00.00.00.00.20.00.10.50.10.40.9-0.40.50.50.0-0.1
Total zone transitions, NPP test0.91.32.91.21.71.11.11.71.11.21.71.71.61.61.61.61.00.90.80.90.60.50.20.8-0.1-0.1-0.00.3
Total locomotion distance, NPP test0.20.30.80.30.80.30.30.90.40.50.80.90.70.70.70.70.10.1-0.00.1-0.2-0.1-0.40.2-0.5-0.50.6-0.4
Locomotion velocity, NPP test0.20.21.1-0.20.4-0.1-0.10.50.00.10.50.50.40.40.40.4-0.3-0.4-0.5-0.1-0.7-0.2-0.6-0.5-0.6-0.61.1-1.0
Intraocular pressure0.30.52.5-0.20.60.1-0.10.60.40.40.70.70.70.70.70.7-0.1-0.5-0.70.7-0.90.30.4-1.5-0.0-0.11.6-1.3
Delta distance traveled before/after self-admin2.42.53.31.61.41.71.71.31.61.61.41.31.51.51.51.51.71.71.81.61.81.71.71.51.71.7-1.51.4
Delta ambulatory time before/after self-admin2.02.54.11.61.31.71.71.31.61.61.41.31.51.51.51.51.81.71.71.61.71.71.71.32.01.9-1.41.3
Parametrial fat weight7.216.923.84.94.04.54.63.84.24.03.83.73.93.93.93.94.44.94.93.84.83.83.54.72.92.9-4.43.9
Pavlov. Cond. lever latency0.20.30.70.30.80.50.40.80.60.60.80.80.70.70.70.70.40.20.10.4-0.10.60.2-0.40.50.50.5-0.2
Pavlov. Cond. magazine entry latency0.20.31.20.5-0.10.40.4-0.10.30.2-0.1-0.1-0.1-0.1-0.1-0.10.50.60.70.50.80.41.00.70.60.6-1.11.1
Pavlov. Cond. change in total contacts0.80.81.4-0.9-1.2-1.0-1.0-1.2-1.0-1.0-1.1-1.2-0.9-0.9-0.9-0.9-0.9-0.8-0.8-0.8-0.8-0.9-0.8-0.4-0.8-0.80.4-0.4
Pavlov. Cond. index score0.20.21.20.4-0.20.20.3-0.30.0-0.1-0.3-0.3-0.2-0.2-0.2-0.20.20.50.60.20.80.10.50.90.10.2-1.10.9
Pavlov. Cond. latency score0.20.31.60.2-0.50.00.1-0.5-0.2-0.3-0.5-0.5-0.5-0.5-0.5-0.50.10.50.6-0.00.7-0.10.31.1-0.1-0.0-1.31.0
Pavlov. Cond. lever contacts0.20.20.5-0.3-0.7-0.4-0.3-0.7-0.5-0.6-0.7-0.7-0.7-0.7-0.7-0.7-0.4-0.1-0.0-0.40.1-0.4-0.10.3-0.4-0.4-0.50.2
Pavlov. Cond. magazine entry number0.10.10.8-0.3-0.1-0.3-0.3-0.1-0.3-0.2-0.1-0.0-0.1-0.1-0.1-0.1-0.3-0.4-0.4-0.5-0.5-0.4-0.9-0.3-0.5-0.50.5-0.6
Pavlov. Cond. intertrial magazine entries0.30.40.90.30.90.30.20.90.40.50.90.91.01.01.01.00.0-0.0-0.10.5-0.3-0.10.1-0.4-0.7-0.70.8-0.8
Pavlov. Cond. lever-magazine prob. diff.0.10.20.90.3-0.20.20.3-0.20.1-0.0-0.2-0.2-0.1-0.1-0.1-0.10.20.50.60.30.70.20.60.70.30.3-0.90.7
Pavlov. Cond. response bias0.20.20.70.40.00.30.4-0.00.30.2-0.0-0.00.10.10.10.10.40.50.60.50.70.40.80.60.30.4-0.80.8
Pavlov. Cond. lever latency1.62.24.01.61.31.61.61.21.51.51.21.21.11.11.11.11.81.71.71.31.71.61.51.22.02.0-1.41.6
Pavlov. Cond. magazine entry latency1.92.35.2-1.5-1.5-1.6-1.5-1.5-1.7-1.8-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.2-1.2-1.6-1.1-1.9-1.9-0.1-2.3-2.30.4-0.1
Pavlov. Cond. change in total contacts1.21.93.7-1.4-1.3-1.5-1.5-1.3-1.6-1.5-1.3-1.2-1.2-1.2-1.2-1.2-1.5-1.4-1.4-1.3-1.3-1.7-1.6-0.7-1.9-1.90.9-0.8
Pavlov. Cond. index score2.33.15.9-1.9-1.6-1.9-1.9-1.5-1.9-1.9-1.5-1.5-1.4-1.4-1.4-1.4-2.0-1.9-1.9-1.6-1.9-2.1-2.0-1.2-2.4-2.41.4-1.4
Pavlov. Cond. latency score2.73.56.4-2.0-1.6-2.0-2.0-1.6-2.0-1.9-1.6-1.6-1.5-1.5-1.5-1.5-2.1-2.1-2.0-1.8-2.1-2.2-2.1-1.4-2.5-2.51.6-1.5
Pavlov. Cond. lever contacts1.11.53.6-1.2-1.1-1.3-1.3-1.1-1.3-1.3-1.1-1.0-0.9-0.9-0.9-0.9-1.4-1.2-1.2-1.1-1.2-1.5-1.3-0.6-1.9-1.90.8-1.1
Pavlov. Cond. magazine entry number2.02.54.71.61.51.71.61.61.81.81.61.51.61.61.61.61.51.41.31.71.22.02.00.42.22.2-0.60.2
Pavlov. Cond. intertrial magazine entries2.33.54.62.02.02.01.92.02.12.12.02.02.12.12.12.11.91.81.72.01.61.91.80.91.81.8-0.90.5
Pavlov. Cond. lever-magazine prob. diff.2.12.95.1-1.9-1.5-1.8-1.8-1.5-1.8-1.8-1.4-1.4-1.4-1.4-1.4-1.4-1.9-1.8-1.8-1.6-1.9-2.0-1.9-1.2-2.3-2.21.4-1.4
Pavlov. Cond. response bias1.72.34.6-1.6-1.5-1.6-1.6-1.5-1.7-1.7-1.5-1.4-1.4-1.4-1.4-1.4-1.7-1.5-1.4-1.5-1.4-1.8-1.7-0.7-2.1-2.10.8-0.9
Time in closed arm before self-admin1.41.84.01.61.01.41.51.11.21.11.01.01.01.01.01.01.41.71.81.01.81.11.12.01.31.1-1.81.7
Time in closed arm after self-admin0.40.40.7-0.6-0.8-0.7-0.7-0.8-0.7-0.8-0.8-0.7-0.7-0.7-0.7-0.7-0.7-0.6-0.6-0.7-0.6-0.7-0.8-0.4-0.6-0.70.4-0.2
Time in open arm before self-admin3.94.26.2-2.5-2.1-2.2-2.3-2.1-2.1-2.1-2.0-1.9-2.0-2.0-2.0-2.0-2.3-2.3-2.3-2.0-2.3-1.9-1.9-2.0-1.3-1.71.9-2.1
Time in open arm after self-admin0.50.61.4-0.7-0.6-0.9-0.8-0.6-0.8-0.7-0.6-0.6-0.6-0.6-0.6-0.6-0.8-1.0-1.0-0.7-0.9-0.6-0.5-1.0-0.1-0.20.9-1.2
Bone: periosteal estimation0.20.50.8-0.9-0.8-0.8-0.8-0.8-0.9-0.8-0.8-0.8-0.7-0.7-0.7-0.7-0.8-0.7-0.7-0.5-0.6-0.8-0.5-0.2-0.8-0.80.2-0.4
Bone: periosteal perimeter0.10.10.4-0.4-0.1-0.3-0.3-0.1-0.2-0.2-0.1-0.1-0.2-0.2-0.2-0.2-0.3-0.5-0.40.1-0.4-0.10.2-0.6-0.1-0.00.5-0.5
Bone: post-yield work0.40.51.90.70.50.70.70.50.60.50.50.50.40.40.40.40.80.91.00.61.00.50.81.10.40.5-1.21.4
Progressive ratio test 1 active lever presses0.10.10.7-0.3-0.0-0.3-0.30.0-0.2-0.2-0.0-0.2-0.1-0.1-0.1-0.1-0.5-0.4-0.40.0-0.5-0.3-0.2-0.6-0.6-0.40.6-0.8
Progressive ratio test 1 breakpoint0.10.10.7-0.20.1-0.2-0.20.1-0.1-0.10.1-0.10.00.00.00.0-0.4-0.4-0.40.1-0.5-0.2-0.1-0.7-0.5-0.40.6-0.8
Progressive ratio test 1 inactive lever presses1.31.83.2-1.7-1.3-1.5-1.5-1.2-1.3-1.2-1.1-1.1-1.1-1.1-1.1-1.1-1.5-1.7-1.7-1.1-1.7-1.1-0.9-1.8-0.9-1.01.7-1.8
Progressive ratio test 2 active lever presses0.50.61.30.51.00.60.61.10.80.91.01.01.01.01.01.00.40.20.11.00.00.81.2-0.70.60.60.5-0.8
Progressive ratio test 2 breakpoint0.60.71.40.51.10.70.61.10.91.01.01.01.01.01.01.00.40.20.21.00.10.91.2-0.60.70.70.5-0.8
Progressive ratio test 2 inactive lever presses0.20.31.6-0.4-0.0-0.3-0.30.2-0.10.10.10.40.10.10.10.1-0.4-0.7-0.70.2-0.80.00.3-1.30.00.11.1-1.2
Incentive Sensitization - Responses0.81.12.00.91.21.01.01.31.21.31.21.41.31.31.31.30.90.60.51.20.41.21.4-0.31.11.00.1-0.2
Incentive Sensitization - Breakpoint0.81.01.90.81.21.00.91.21.11.21.11.31.21.21.21.20.90.60.51.20.51.21.4-0.31.11.00.1-0.1
Sum of active levers in priming session hrs 5-62.42.33.71.81.21.61.61.11.41.41.21.11.21.21.21.21.71.81.91.31.91.41.41.81.61.4-1.91.8
Progressive ratio0.10.20.90.00.3-0.2-0.20.2-0.1-0.00.30.30.20.20.20.2-0.4-0.6-0.50.3-0.6-0.20.3-0.8-0.6-0.60.9-1.0
Food seeking constrained by brief footshock0.00.00.1-0.2-0.1-0.1-0.2-0.1-0.1-0.1-0.1-0.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.3-0.30.3-0.3
Seeking ratio, punishment vs. effort0.50.81.6-0.9-1.1-0.8-0.8-1.1-0.9-0.9-1.1-1.1-1.1-1.1-1.1-1.1-0.6-0.4-0.4-1.3-0.4-0.9-1.20.2-0.6-0.6-0.20.4
Retroperitoneal fat weight0.10.61.60.80.80.80.80.70.70.60.70.80.80.80.80.80.61.00.90.50.80.30.21.3-0.3-0.4-0.90.6
Reaction time number correct0.00.10.30.50.30.30.30.20.20.30.20.20.40.40.40.40.30.30.40.20.40.10.00.5-0.0-0.0-0.40.1
Reaction time mean minus median0.10.10.8-0.20.20.0-0.10.20.20.20.20.20.30.30.30.30.1-0.3-0.40.4-0.40.30.4-0.90.30.30.8-0.4
Reaction time mean minus median AUC0.61.42.30.91.41.11.01.41.31.31.41.41.51.51.51.51.10.70.61.40.41.31.3-0.21.31.30.3-0.1
Reaction time num false alarms0.30.41.40.20.90.20.10.80.40.50.80.90.90.90.90.90.2-0.3-0.40.6-0.60.20.4-0.9-0.2-0.11.2-1.0
Reaction time num false alarms AUC0.30.41.40.10.80.10.10.70.30.50.70.80.80.80.80.80.2-0.4-0.40.6-0.60.10.4-0.9-0.1-0.11.2-0.9
Reaction time trials correct on left0.00.10.30.50.30.30.30.20.20.30.20.20.40.40.40.40.30.30.40.20.40.10.00.5-0.0-0.0-0.40.1
Reaction time trials on left0.10.10.20.50.30.30.30.20.20.30.20.20.40.40.40.40.30.30.40.20.40.10.10.5-0.00.0-0.40.0
Reaction time mean0.00.00.2-0.3-0.2-0.1-0.2-0.2-0.0-0.1-0.2-0.2-0.1-0.1-0.1-0.10.0-0.2-0.30.1-0.30.10.3-0.50.30.20.30.2
Reaction time mean AUC0.10.10.8-0.6-0.3-0.3-0.4-0.3-0.2-0.3-0.3-0.3-0.2-0.2-0.2-0.2-0.2-0.5-0.60.0-0.60.00.1-0.90.20.10.7-0.2
Median of all reaction times0.10.10.2-0.5-0.4-0.3-0.4-0.5-0.3-0.4-0.5-0.5-0.4-0.4-0.4-0.4-0.2-0.3-0.3-0.2-0.3-0.10.0-0.40.0-0.00.10.3
Reaction time omissions0.10.10.30.30.20.30.30.20.30.30.20.30.40.40.40.40.60.30.20.40.30.40.40.20.50.5-0.00.4
Reaction time false alarm rate0.20.31.20.10.70.10.10.70.30.40.70.70.70.70.70.70.2-0.3-0.40.5-0.50.20.4-0.90.10.21.1-0.7
Reaction time premature initiation rate0.60.91.51.01.01.01.01.01.01.11.01.01.01.01.01.00.90.80.80.90.71.10.90.31.21.2-0.40.2
Reaction time premature initiations0.61.01.51.11.11.11.11.11.11.21.11.11.21.21.21.21.00.90.91.00.81.10.90.51.11.1-0.40.1
Std. dev. reaction times0.10.20.7-0.10.30.10.00.30.30.30.30.30.40.40.40.40.2-0.2-0.30.6-0.30.50.7-0.80.60.60.7-0.4
Reaction time trials completed0.10.10.20.50.30.30.30.20.20.30.20.20.40.40.40.40.30.30.40.20.40.10.10.5-0.00.0-0.40.0
Reaction time trials AUC0.00.10.20.50.30.30.30.20.20.30.20.20.40.40.40.40.30.30.30.20.30.10.00.40.00.0-0.30.0
Run reversals in cocaine runway, females0.20.21.3-0.60.3-0.0-0.10.50.20.20.40.50.30.30.30.3-0.3-0.4-0.50.1-0.60.1-0.1-0.90.1-0.11.0-1.2
Run reversals in cocaine runway, males0.60.61.00.61.00.70.71.00.90.91.01.00.90.90.90.90.70.40.31.00.20.81.0-0.30.70.70.5-0.2
Latency to leave start box in cocaine runway0.20.20.6-0.6-0.5-0.4-0.4-0.6-0.5-0.5-0.4-0.5-0.4-0.4-0.4-0.4-0.5-0.3-0.3-0.4-0.3-0.5-0.4-0.0-0.8-0.60.1-0.1
Latency to leave start box in cocaine runway, F0.10.10.3-0.3-0.4-0.2-0.1-0.6-0.3-0.4-0.4-0.5-0.4-0.4-0.4-0.4-0.30.00.1-0.40.2-0.4-0.40.6-0.6-0.4-0.50.2
Latency to leave start box in cocaine runway, M0.10.10.2-0.2-0.2-0.2-0.2-0.1-0.2-0.2-0.1-0.20.00.00.00.0-0.2-0.3-0.3-0.0-0.3-0.2-0.1-0.4-0.3-0.30.5-0.1
Std. dev. time between licks in bursts0.20.30.50.60.60.50.50.70.50.60.70.70.60.60.60.60.40.40.40.70.40.40.50.20.20.2-0.2-0.1
Total sessions with >9 infusions0.10.20.90.00.40.10.10.40.20.30.40.20.40.40.40.4-0.1-0.2-0.20.4-0.30.30.2-0.60.30.20.7-1.0
Short access day 1 total inactive lever presses0.10.10.50.20.30.30.30.30.30.30.30.30.20.20.20.20.20.20.30.30.30.30.60.10.70.4-0.20.0
Short access day 10 total inactive lever presses0.40.91.5-1.2-1.1-1.1-1.0-0.9-1.0-0.9-0.9-0.8-0.9-0.9-0.9-0.9-1.0-1.2-1.1-0.9-1.1-0.8-0.6-1.0-0.2-0.41.1-1.0
Short access day 1 total infusions0.40.53.2-0.7-0.2-0.6-0.6-0.1-0.4-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.8-0.9-1.0-0.2-1.0-0.2-0.2-1.3-0.1-0.21.3-1.8
Short access day 10 total infusions0.20.21.2-0.20.1-0.2-0.20.2-0.00.10.20.10.20.20.20.2-0.4-0.5-0.50.2-0.6-0.00.0-0.9-0.4-0.41.0-1.1
Short access total infusions0.30.42.7-0.7-0.2-0.5-0.6-0.2-0.4-0.3-0.2-0.3-0.2-0.2-0.2-0.2-0.8-0.8-0.9-0.1-0.9-0.3-0.3-1.1-0.3-0.31.2-1.6
Short access day 1 locomotion1.41.73.1-1.5-0.9-1.4-1.4-1.0-1.3-1.2-1.0-1.0-1.0-1.0-1.0-1.0-1.5-1.7-1.6-0.9-1.6-1.2-0.9-1.5-1.4-1.31.6-1.8
Short access day 10 total locomotion0.51.02.5-1.2-0.8-1.1-1.1-0.8-1.0-0.9-0.8-0.9-0.6-0.6-0.6-0.6-1.0-1.3-1.3-0.8-1.3-0.9-1.1-1.2-0.6-0.71.6-1.2
Short access total locomotion1.72.04.2-1.7-1.0-1.6-1.6-1.1-1.4-1.2-1.1-1.1-1.0-1.0-1.0-1.0-1.6-1.9-1.9-1.1-1.9-1.3-1.3-1.8-1.1-1.12.0-2.0
One hour access (0.3 mA shock)1.01.11.90.91.31.01.01.31.11.21.31.21.31.31.31.30.90.70.71.40.61.11.3-0.10.91.00.0-0.3
Compulsive drug intake0.50.52.20.90.50.70.70.30.50.40.40.30.30.30.30.30.71.01.00.31.10.50.51.30.50.4-1.51.2
One hour access (shock baseline)0.10.10.6-0.10.2-0.0-0.10.30.10.20.20.20.30.30.30.3-0.1-0.2-0.30.4-0.40.00.3-0.7-0.20.00.7-0.8
Social response proportion1.51.76.11.60.71.21.40.61.00.90.60.60.70.70.70.71.51.71.80.82.00.90.92.10.80.9-2.22.5
Social responses1.52.04.61.81.11.41.51.01.21.21.10.91.31.31.31.31.81.61.71.21.71.11.31.80.90.9-1.72.2
Social time2.33.24.72.21.61.91.91.51.81.71.61.41.61.61.61.62.12.12.11.82.11.61.91.81.41.4-1.92.1
Soleus weight3.09.016.43.52.73.23.32.62.82.82.62.52.52.52.52.53.53.73.82.23.82.41.94.02.22.2-3.83.8
Bone: stiffness0.50.93.61.00.50.80.90.50.50.50.50.40.40.40.40.41.01.21.30.51.40.30.51.90.30.4-1.81.9
Tibialis anterior weight9.331.639.86.16.36.06.06.26.06.16.26.26.16.16.16.15.95.45.36.05.15.75.63.65.15.2-3.22.8
Time to tail flick, vehicle, before self-admin7.37.68.82.92.93.03.02.82.92.92.82.82.92.92.92.93.02.92.82.82.72.82.72.12.92.6-2.01.9
Time to tail flick, vehicle, after self-admin0.30.40.70.80.70.70.70.70.70.70.70.70.70.70.70.70.70.70.60.80.60.60.80.40.50.3-0.40.5
Time to tail flick, test, before self-admin0.70.81.31.00.80.91.00.70.80.80.70.80.70.70.70.70.91.11.10.71.10.80.61.10.70.8-1.11.0
Time to tail flick, test, after self-admin0.10.10.3-0.3-0.5-0.3-0.3-0.5-0.4-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.3-0.1-0.1-0.4-0.1-0.3-0.10.10.1-0.1-0.20.0
Delta time to tail flick, vehicle, before/after SA1.11.11.7-1.1-1.0-1.1-1.2-0.9-1.0-1.0-0.9-0.9-0.9-0.9-0.9-0.9-1.1-1.3-1.3-0.8-1.3-0.9-0.7-1.3-0.9-0.91.2-1.1
Delta time to tail flick, test, before/after SA0.30.31.1-0.6-0.4-0.5-0.6-0.3-0.3-0.3-0.3-0.4-0.3-0.3-0.3-0.3-0.6-0.7-0.8-0.2-0.8-0.2-0.0-1.00.0-0.11.0-1.0
Tibia length0.41.22.1-0.4-1.2-0.7-0.5-1.3-1.0-1.2-1.3-1.3-1.4-1.4-1.4-1.4-0.60.00.2-1.10.4-1.0-0.91.3-1.1-1.1-1.51.4
Ambulatory time before self-admin4.36.49.0-2.4-2.5-2.7-2.7-2.5-2.7-2.7-2.6-2.5-2.7-2.7-2.7-2.7-2.7-2.5-2.5-2.7-2.4-2.8-2.6-1.5-3.0-2.91.6-1.4
Ambulatory time after self-admin0.50.51.0-0.4-0.9-0.7-0.6-1.0-0.8-0.9-1.0-1.0-0.9-0.9-0.9-0.9-0.6-0.3-0.2-0.9-0.1-0.9-0.70.4-0.8-0.7-0.40.4
Bone: tissue strength2.62.74.1-1.5-1.8-1.8-1.7-1.7-1.9-1.8-1.7-1.8-1.7-1.7-1.7-1.7-1.5-1.6-1.4-1.8-1.3-2.0-1.9-0.8-2.0-1.90.7-0.3
Total heroin consumption4.35.06.82.52.12.42.52.12.22.22.12.02.12.12.12.12.52.62.62.22.62.12.02.21.91.9-2.32.3
Bone: trabecular number5.08.310.03.23.23.23.13.13.13.03.13.13.03.03.03.03.03.13.02.92.82.82.62.42.52.4-1.91.9
Bone: trabecular spacing0.70.91.4-1.0-1.0-1.1-1.0-0.9-1.0-0.9-0.9-1.0-0.9-0.9-0.9-0.9-0.9-1.2-1.1-0.8-1.0-1.0-0.8-1.0-0.8-0.70.8-0.7
Bone: trabecular thickness0.50.60.70.90.90.80.80.80.80.80.80.80.80.80.80.80.80.90.80.70.80.60.70.80.50.5-0.60.7
Bone: trabecular tissue density2.33.34.5-2.1-2.0-2.0-2.0-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.7-1.9-1.5-1.5-1.61.3-1.2
Water consumed over 24 hours0.60.81.5-0.8-1.2-0.8-0.7-1.2-1.0-1.0-1.2-1.2-1.0-1.0-1.0-1.0-0.7-0.4-0.3-1.1-0.2-1.0-1.10.6-0.9-0.9-0.50.3
Number of responses in last shaping day1.41.53.9-1.5-0.9-1.3-1.3-0.8-1.2-1.0-0.8-0.8-0.8-0.8-0.8-0.8-1.5-1.6-1.6-0.8-1.6-1.0-0.7-1.6-1.1-1.11.7-2.0