Hub : Genes

Crk

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Crk 0.17 0.09 4.3e-07 0.11 0.11 0.12 0.12 1.3e-06 2.2e-06 8.4e-07 1.1e-06
2 PL gene expression Crk 0.22 0.1 0.0e+00 0.21 0.2 0.2 0.21 4.3e-22 9.9e-22 1.8e-21 3.1e-22
3 OFC gene expression Crk 0.29 0.13 1.1e-05 0.2 0.24 0.24 0.2 1.6e-05 2.2e-06 2.4e-06 1.3e-05
4 LHb gene expression Crk 0.36 0.15 1.5e-06 0.22 0.27 0.23 0.2 7.1e-06 3.5e-07 4.1e-06 1.4e-05
5 Brain gene expression Crk 0.33 0.13 0.0e+00 0.25 0.25 0.25 0.26 7.2e-23 2.5e-23 1.3e-23 2.8e-24
6 IL gene expression Crk 0.2 0.13 9.2e-04 0.02 0.03 0.03 0.02 1.1e-01 6.7e-02 6.7e-02 1.1e-01
7 NAcc mRNA stability Crk 0.23 0.1 0.0e+00 0.21 0.22 0.22 0.22 1.3e-31 9.4e-33 1.1e-32 2.8e-32
8 BLA mRNA stability Crk 0.32 0.08 0.0e+00 0.28 0.28 0.28 0.28 2.1e-15 1.9e-15 3.7e-15 2.6e-15
9 Brain mRNA stability Crk 0.36 0.11 0.0e+00 0.26 0.27 0.27 0.27 7.5e-24 8.5e-25 4.7e-25 3.8e-25
10 IC mRNA stability Crk 0.39 0.15 8.2e-12 0.3 0.17 0.26 0.1 3.2e-13 1.5e-07 1.5e-11 7.9e-05
11 RMTg gene expression Crk 0.18 0.12 4.0e-03 0.11 0.1 0.09 0.12 8.0e-04 1.5e-03 1.8e-03 5.1e-04
12 Liver mRNA stability Crk 0.09 0.06 4.3e-06 0.04 0.03 0.03 0.03 6.1e-05 3.8e-04 3.4e-04 3.8e-04
13 IL mRNA stability Crk 0.2 0.12 1.5e-03 0.11 0.03 0.07 -0.01 1.5e-03 5.6e-02 8.5e-03 5.2e-01
14 pVTA gene expression Crk 0.18 0.1 2.6e-12 0.17 0.12 0.16 0.14 7.8e-14 3.4e-10 1.7e-12 4.6e-11
15 Adipose mRNA stability Crk 0.17 0.08 0.0e+00 0.13 0.14 0.13 0.14 8.0e-14 5.8e-15 1.1e-14 3.8e-15
16 OFC mRNA stability Crk 0.17 0.11 9.9e-04 0.06 0.14 0.1 0.12 1.5e-02 4.3e-04 2.2e-03 1.1e-03
17 PL mRNA stability Crk 0.28 0.1 0.0e+00 0.28 0.28 0.28 0.29 9.7e-31 3.5e-31 4.4e-31 1.8e-31
18 Liver gene expression Crk 0.13 0.07 0.0e+00 0.09 0.13 0.12 0.12 5.9e-10 7.3e-14 1.2e-13 1.2e-13
19 NAcc gene expression Crk 0.51 0.17 0.0e+00 0.23 0.23 0.23 0.23 9.4e-34 7.7e-35 8.9e-34 7.1e-34
20 pVTA mRNA stability Crk 0.25 0.12 0.0e+00 0.26 0.2 0.24 0.11 3.0e-21 1.2e-15 1.5e-19 2.1e-09
21 IC gene expression Crk 0.35 0.15 3.6e-11 0.28 0.12 0.28 0.06 5.1e-12 1.2e-05 2.2e-12 2.1e-03
22 Brain intron excision ratio chr10_61040004_61051412 0.03 0.03 9.0e-03 0.01 0 0 0 5.3e-02 1.7e-01 2.3e-01 1.1e-01
23 LHb mRNA stability Crk 0.29 0.14 9.6e-06 0.19 0.13 0.18 0.15 2.9e-05 5.8e-04 5.1e-05 2.4e-04
24 NAcc intron excision ratio chr10_61040174_61051412 0.01 0.01 6.4e-03 0.01 0.01 0 0 1.3e-02 2.6e-02 1.4e-01 4.7e-02
25 Adipose gene expression Crk 0.02 0.02 6.9e-03 0.01 0.01 0 0.01 2.1e-02 2.8e-02 1.0e-01 3.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density4.38.09.8-3.13.03.13.13.0-3.03.02.93.0-3.02.9-2.9-2.9-2.93.03.02.82.92.8-2.6-2.5-2.5-2.52.0-2.1
Area under the delay curve1.21.83.01.2-1.4-1.5-1.5-1.31.4-1.5-1.5-1.31.3-1.21.21.21.2-1.5-1.4-1.4-1.3-1.61.60.71.71.6-1.01.0
BMI with tail1.13.75.2-2.32.12.02.12.0-2.21.92.02.0-2.12.1-2.1-2.1-2.11.91.92.21.91.7-2.2-1.4-1.6-1.71.4-0.8
BMI without tail0.52.57.3-2.01.21.61.71.1-2.01.21.21.0-1.11.2-1.2-1.2-1.21.62.11.22.31.0-1.2-2.7-0.7-0.72.5-2.4
Body weight1.04.218.8-2.51.21.92.11.0-2.51.31.20.9-1.01.1-1.1-1.1-1.12.02.90.83.20.7-0.7-4.3-0.2-0.24.0-3.6
Weight adjusted by age0.20.61.0-0.71.00.80.81.0-0.70.80.91.0-1.01.0-1.0-1.0-1.00.70.50.90.50.8-0.9-0.1-0.6-0.60.0-0.0
Bone surface3.87.49.8-3.03.12.92.93.1-2.92.82.93.1-3.13.0-3.0-3.0-3.02.82.72.92.52.5-2.5-2.1-2.0-2.01.6-1.5
Bone volume3.87.59.8-3.13.12.92.93.1-2.92.82.93.1-3.13.1-3.1-3.1-3.12.82.72.92.52.5-2.6-2.2-2.0-2.01.6-1.5
Breakpoint value in progressive ratio session0.51.02.5-1.10.81.01.10.7-1.20.80.80.8-0.70.8-0.8-0.8-0.81.11.30.71.40.6-0.6-1.6-0.7-0.51.5-1.5
Number of licking bursts0.30.92.61.0-0.8-0.9-1.0-0.80.9-1.0-0.9-0.80.8-0.70.70.70.7-0.9-0.8-1.0-0.9-1.31.40.31.51.6-0.60.7
Context. condit. distance diff. score1.41.82.5-1.41.21.51.51.2-1.41.51.41.2-1.21.2-1.2-1.2-1.21.41.51.31.41.6-1.3-1.1-1.5-1.51.2-0.8
Locomotion velocity, session 12.93.35.0-2.11.62.02.01.6-2.01.81.81.6-1.51.7-1.7-1.7-1.72.02.21.52.21.7-1.3-2.2-1.6-1.62.0-1.9
Locomotion distance, session 10.60.81.4-1.01.21.01.01.2-0.80.91.01.2-1.21.1-1.1-1.1-1.10.90.80.70.70.7-0.3-0.8-0.5-0.50.3-0.4
Locomotion velocity, session 20.81.01.2-1.11.11.11.11.1-1.01.11.11.1-1.11.1-1.1-1.1-1.11.11.00.81.01.0-0.6-1.0-0.9-0.90.7-0.7
Locomotion distance, session 21.72.43.6-1.71.91.71.71.9-1.51.61.71.9-1.91.7-1.7-1.7-1.71.71.51.41.41.4-1.1-1.2-1.3-1.30.8-1.1
Locomotion velocity, session 35.66.49.52.5-2.6-2.7-2.6-2.62.6-2.8-2.7-2.62.6-2.52.52.52.5-2.7-2.4-2.8-2.2-3.03.11.12.92.9-1.21.3
Locomotion distance, session 30.10.10.20.10.2-0.2-0.10.20.2-0.20.00.2-0.20.2-0.2-0.2-0.2-0.1-0.4-0.1-0.3-0.30.50.20.20.1-0.50.5
Stereotopy head waving bouts, day 30.10.10.5-0.1-0.4-0.1-0.1-0.40.0-0.3-0.3-0.40.5-0.20.20.20.2-0.10.1-0.50.2-0.50.6-0.60.40.40.6-0.7
Stereotopy head waving duration, day 30.30.41.20.4-0.5-0.6-0.6-0.40.6-0.6-0.5-0.40.5-0.10.10.10.1-0.7-0.5-0.7-0.6-0.91.00.21.11.1-0.50.7
Locomotion velocity, session 71.21.31.8-1.21.31.11.21.3-1.11.21.31.3-1.31.2-1.2-1.2-1.21.20.91.20.91.2-1.2-0.3-1.3-1.30.3-0.3
Locomotion distance, session 71.92.43.3-1.51.71.61.61.7-1.51.61.71.7-1.71.7-1.7-1.7-1.71.61.31.81.31.7-1.8-0.6-1.8-1.80.6-0.6
Stereotopy head waving bouts, day 70.80.92.2-1.30.91.01.00.9-1.00.80.90.9-0.81.2-1.2-1.2-1.20.91.10.51.10.40.2-1.5-0.1-0.11.1-0.9
Stereotopy head waving duration, day 71.11.42.5-1.61.31.21.21.3-1.21.11.21.3-1.21.6-1.6-1.6-1.61.21.30.81.20.5-0.1-1.5-0.1-0.21.0-0.9
Locomotion velocity, session 80.50.60.9-0.61.00.80.81.0-0.60.90.91.0-1.00.9-0.9-0.9-0.90.70.60.80.51.0-0.6-0.2-0.7-0.70.10.1
Locomotion distance, session 82.23.24.3-2.01.92.02.01.9-1.91.91.81.9-1.91.7-1.7-1.7-1.71.92.11.52.01.7-1.2-2.0-1.4-1.41.7-1.4
Degree of sensitization distance1.21.32.7-1.20.91.21.20.9-1.41.21.00.9-0.90.8-0.8-0.8-0.81.31.41.21.31.3-1.6-0.9-1.3-1.31.2-1.3
Degree of sensitization stereotypy1.11.22.4-1.51.11.21.21.1-1.21.11.11.1-1.01.3-1.3-1.3-1.31.21.30.71.30.7-0.2-1.6-0.4-0.31.2-1.1
Conditioned locomotion0.20.21.10.5-0.5-0.5-0.6-0.40.5-0.4-0.4-0.40.4-0.30.30.30.3-0.5-0.6-0.0-0.7-0.3-0.11.10.00.0-0.80.6
Cocaine response after cond. corrected0.10.10.5-0.1-0.10.30.3-0.1-0.30.20.1-0.10.1-0.10.10.10.10.20.50.00.50.4-0.2-0.5-0.5-0.50.7-0.7
Cocaine response after cond. not corrected0.20.30.8-0.50.30.60.60.3-0.60.50.40.3-0.30.3-0.3-0.3-0.30.50.80.40.90.6-0.4-0.9-0.5-0.50.9-0.9
Cocaine response before conditioning1.01.11.7-1.21.31.11.21.2-1.11.01.11.2-1.31.3-1.3-1.3-1.31.01.11.11.10.8-0.8-1.2-0.3-0.40.7-0.5
Saline control response0.30.51.0-0.61.00.60.61.0-0.50.60.71.0-1.01.0-1.0-1.0-1.00.50.40.60.30.3-0.2-0.50.20.2-0.10.2
Bone: connectivity density6.610.612.9-3.63.63.53.53.5-3.43.43.53.5-3.63.4-3.4-3.4-3.43.53.33.23.13.2-2.9-2.5-2.8-2.92.1-2.3
Bone: cortical apparent density0.20.41.70.7-0.3-0.5-0.6-0.30.8-0.3-0.3-0.20.3-0.20.20.20.2-0.5-0.8-0.3-1.0-0.00.41.3-0.1-0.1-1.21.1
Bone: cortical area1.83.04.02.0-1.9-1.9-1.8-1.81.8-1.9-1.9-1.81.8-2.02.02.02.0-1.8-1.8-1.7-1.6-1.71.51.21.51.4-0.90.9
Bone: cortical porosity0.10.10.3-0.50.20.40.40.2-0.40.30.30.3-0.20.3-0.3-0.3-0.30.30.40.20.50.4-0.3-0.5-0.2-0.20.4-0.2
Bone: cortical porosity0.00.00.10.0-0.2-0.1-0.1-0.20.1-0.2-0.2-0.20.2-0.10.10.10.1-0.2-0.0-0.20.0-0.10.1-0.20.30.30.10.1
Bone: cortical thickness6.410.613.93.4-3.6-3.4-3.4-3.63.4-3.5-3.5-3.63.6-3.73.73.73.7-3.3-3.0-3.6-2.7-3.33.51.72.92.9-1.41.4
Bone: cortical thickness1.41.73.11.2-1.5-1.3-1.2-1.51.2-1.4-1.5-1.61.5-1.71.71.71.7-1.3-0.9-1.6-0.6-1.31.50.01.01.10.10.1
Bone: cortical tissue density0.10.21.20.5-0.2-0.3-0.4-0.10.6-0.1-0.1-0.10.1-0.10.10.10.1-0.3-0.6-0.1-0.80.10.21.1-0.3-0.2-1.00.8
Condit. Reinf. active minus inactive responses0.30.40.70.3-0.8-0.6-0.6-0.80.4-0.7-0.7-0.80.9-0.70.70.70.7-0.4-0.4-0.6-0.2-0.90.6-0.20.80.70.2-0.2
Condit. Reinf. active-inactive response ratio2.93.14.91.4-2.1-1.7-1.6-2.21.3-2.0-2.0-2.22.2-2.12.12.12.1-1.3-1.1-1.9-0.8-2.11.8-0.21.91.90.3-0.5
Condit. Reinf. active responses0.20.30.7-0.70.50.50.50.4-0.60.50.50.4-0.40.5-0.5-0.5-0.50.60.50.70.50.4-0.8-0.2-0.5-0.50.3-0.3
Condit. Reinf. inactive responses3.34.37.2-1.82.52.01.92.5-1.72.32.32.5-2.52.5-2.5-2.5-2.51.71.42.50.92.3-2.70.4-2.2-2.1-0.30.4
Incentive salience index mean0.20.20.50.1-0.6-0.3-0.3-0.70.1-0.5-0.5-0.70.7-0.60.60.60.6-0.1-0.1-0.50.2-0.50.5-0.50.30.20.6-0.4
Condit. Reinf. lever presses0.30.52.2-0.80.20.60.70.1-0.80.40.40.1-0.10.1-0.1-0.1-0.10.70.90.21.20.5-0.3-1.3-0.8-0.81.5-1.0
Condit. Reinf. active minus inactive responses0.30.50.9-0.80.80.70.80.7-0.80.80.80.8-0.80.8-0.8-0.8-0.80.80.71.00.60.7-0.8-0.5-0.5-0.50.4-0.5
Condit. Reinf. active-inactive response ratio0.10.10.20.2-0.5-0.2-0.2-0.5-0.0-0.2-0.3-0.50.5-0.40.40.40.4-0.1-0.0-0.00.1-0.1-0.0-0.20.10.10.4-0.4
Condit. Reinf. active responses0.91.32.6-1.21.41.11.11.4-1.01.11.21.4-1.41.6-1.6-1.6-1.61.00.81.40.60.9-0.9-0.5-0.3-0.4-0.00.0
Condit. Reinf. inactive responses1.92.96.3-1.72.31.51.42.3-1.21.61.92.3-2.32.5-2.5-2.5-2.51.30.81.80.51.2-1.2-0.1-0.4-0.5-0.70.8
Condit. Reinf. lever presses0.30.52.80.40.1-0.5-0.50.20.5-0.3-0.20.2-0.20.5-0.5-0.5-0.5-0.7-0.90.3-1.0-0.50.11.11.11.0-1.41.7
Condit. Reinf. lever reinforcers received0.81.12.6-1.11.40.90.91.3-0.91.01.11.4-1.41.6-1.6-1.6-1.60.90.61.30.40.7-0.8-0.3-0.1-0.2-0.20.2
Conditioned reinforcement - actives0.62.53.5-1.61.71.61.61.7-1.61.81.81.7-1.81.7-1.7-1.7-1.71.51.31.91.21.9-1.9-0.4-1.6-1.50.4-0.4
Conditioned reinforcement - inactives0.20.40.6-0.50.60.70.70.7-0.60.70.70.7-0.70.7-0.7-0.7-0.70.70.60.70.50.7-0.8-0.4-0.7-0.80.2-0.1
Conditioned locomotion0.20.30.90.5-0.3-0.7-0.6-0.30.6-0.6-0.4-0.40.2-0.10.10.10.1-0.6-0.9-0.3-0.9-0.60.50.80.80.7-0.90.9
Patch foraging indifference point 0 sec0.10.30.6-0.60.70.50.60.7-0.50.60.60.7-0.70.6-0.6-0.6-0.60.50.40.70.40.6-0.8-0.2-0.5-0.50.10.2
Patch foraging indifference point AUC0.10.21.00.4-0.1-0.2-0.3-0.10.5-0.1-0.0-0.00.10.0-0.0-0.0-0.0-0.2-0.5-0.1-0.70.00.10.8-0.3-0.3-1.00.8
Delay disc. indifference point, 0s delay0.10.10.3-0.50.10.20.20.2-0.40.20.30.2-0.30.5-0.5-0.5-0.50.30.30.20.2-0.20.0-0.50.50.50.2-0.5
Delay disc. indifference point, 16s delay1.21.73.11.2-1.2-1.4-1.4-1.21.4-1.4-1.4-1.21.1-1.11.11.11.1-1.5-1.3-1.4-1.3-1.51.80.71.71.6-1.01.0
Delay disc. indifference point, 2s delay1.11.22.00.9-1.0-1.2-1.2-1.01.2-1.2-1.2-1.00.9-1.01.01.01.0-1.3-1.1-1.1-1.1-1.21.20.51.41.3-0.90.9
Delay disc. indifference point, 24s delay0.20.30.50.6-0.6-0.6-0.6-0.50.7-0.6-0.6-0.50.7-0.50.50.50.5-0.7-0.6-0.5-0.6-0.50.70.50.60.7-0.60.6
Delay disc. indifference point, 4s delay1.11.11.91.0-1.4-1.1-1.1-1.31.0-1.1-1.2-1.21.1-1.01.01.01.0-1.1-0.9-1.2-0.8-1.21.30.01.31.3-0.40.4
Delay disc. indifference point, 8s delay0.61.11.60.9-1.1-1.1-1.1-1.01.1-1.1-1.1-1.01.2-1.01.01.01.0-1.2-1.0-1.1-0.9-1.11.10.51.31.2-0.60.8
Indifference point function ln k0.31.01.3-1.21.01.11.11.1-1.11.01.01.0-1.01.0-1.0-1.0-1.01.01.00.91.01.1-0.8-0.9-0.8-0.80.8-0.5
Indifference point function log k0.31.01.3-1.21.01.11.11.1-1.11.01.01.0-1.01.0-1.0-1.0-1.01.01.00.91.01.1-0.8-0.9-0.8-0.80.8-0.5
Patch foraging total patch changes 0 sec0.20.40.8-0.60.80.60.70.8-0.60.70.70.8-0.80.8-0.8-0.8-0.80.60.40.80.50.7-0.9-0.2-0.6-0.60.10.2
Patch foraging total patch changes 12 sec0.30.50.70.7-0.8-0.7-0.7-0.80.6-0.8-0.7-0.80.8-0.80.80.80.8-0.7-0.6-0.7-0.5-0.80.50.20.60.5-0.30.3
Patch foraging total patch changes 18 sec0.41.02.10.8-1.1-1.0-1.0-1.10.9-1.1-1.1-1.01.1-0.90.90.90.9-1.0-0.8-1.3-0.7-1.31.4-0.11.31.3-0.30.3
Patch foraging total patch changes 24 sec0.20.71.10.8-0.8-0.9-0.9-0.80.9-0.9-0.8-0.70.7-0.80.80.80.8-0.8-0.9-0.9-0.8-0.91.00.60.80.8-0.80.6
Patch foraging total patch changes 6 sec0.10.21.70.30.1-0.3-0.30.20.3-0.1-0.00.2-0.20.2-0.2-0.2-0.2-0.5-0.60.1-0.7-0.2-0.20.80.40.3-1.01.3
Patch foraging time to switch 0 sec0.51.83.31.0-1.6-1.2-1.2-1.70.9-1.5-1.6-1.61.7-1.51.51.51.5-1.2-0.7-1.4-0.5-1.51.2-0.41.81.80.5-0.4
Patch foraging water rate 0 sec0.10.51.1-0.40.90.50.41.1-0.30.70.81.0-1.00.9-0.9-0.9-0.90.50.00.8-0.20.7-0.60.7-0.7-0.7-0.70.7
Patch foraging water rate 12 sec0.00.00.2-0.10.20.10.10.2-0.00.10.00.2-0.10.1-0.1-0.1-0.1-0.10.1-0.10.10.00.4-0.30.20.20.10.1
Patch foraging water rate 18 sec1.53.45.4-2.02.22.02.02.3-1.82.12.12.2-2.32.2-2.2-2.2-2.21.81.81.81.61.8-1.4-1.1-1.3-1.20.9-0.7
Patch foraging water rate 24 sec0.20.30.6-0.40.60.40.40.8-0.20.50.60.7-0.70.8-0.8-0.8-0.80.20.20.40.10.4-0.00.1-0.2-0.2-0.20.6
Patch foraging water rate 6 sec0.20.31.00.6-0.3-0.5-0.5-0.20.7-0.4-0.3-0.20.3-0.20.20.20.2-0.5-0.8-0.4-0.8-0.30.70.80.20.2-1.00.8
Seeking ratio, delayed vs. immediate footshock0.91.33.21.1-0.7-1.3-1.3-0.71.3-1.2-1.1-0.60.7-0.50.50.50.5-1.4-1.5-0.8-1.6-1.30.91.31.81.7-1.51.5
Distance traveled before self-admin2.24.86.32.1-2.0-2.4-2.4-2.02.4-2.3-2.3-2.12.0-2.12.12.12.1-2.4-2.4-2.2-2.4-2.42.11.82.52.4-1.91.6
Distance traveled after self-admin0.30.50.80.7-0.9-0.8-0.8-0.80.8-0.8-0.8-0.80.8-0.70.70.70.7-0.7-0.8-0.8-0.7-0.90.60.50.90.8-0.50.3
Extensor digitorum longus weight5.522.028.8-5.15.45.04.95.3-4.75.15.35.3-5.35.3-5.3-5.3-5.35.04.34.83.94.7-4.3-2.4-4.4-4.52.0-2.2
Bone: elastic displacement0.40.51.70.8-0.6-0.7-0.8-0.51.0-0.6-0.6-0.50.5-0.40.40.40.4-0.8-0.9-0.6-1.0-0.40.91.10.30.4-1.21.3
Bone: elastic work5.26.88.62.8-2.8-2.8-2.7-2.82.8-2.9-2.8-2.82.7-2.82.82.82.8-2.7-2.6-2.9-2.3-2.72.91.52.32.3-1.51.7
Bone: endosteal estimation0.20.51.0-0.50.80.60.60.8-0.70.60.70.8-0.81.0-1.0-1.0-1.00.50.51.00.40.5-1.0-0.3-0.3-0.40.10.0
Bone: endosteal perimeter0.92.24.7-1.21.81.41.31.7-1.41.61.61.8-1.71.8-1.8-1.8-1.81.30.92.00.71.5-2.20.1-1.3-1.4-0.1-0.0
Epididymis fat weight4.924.733.8-5.74.95.55.54.9-5.65.14.94.9-4.85.0-5.0-5.0-5.05.35.84.75.64.5-4.2-5.4-3.4-3.44.9-4.6
Delta time in closed arm before/after self-admin0.60.61.60.9-0.5-0.7-0.8-0.60.9-0.6-0.5-0.40.4-0.30.30.30.3-0.7-1.0-0.5-1.2-0.60.71.20.80.8-1.31.0
Delta time in open arm before/after self-admin0.70.91.8-1.40.91.01.00.9-1.00.80.80.8-0.80.8-0.8-0.8-0.80.91.10.71.20.8-0.7-1.3-0.7-0.81.2-0.7
Diff in mean of infusions in LGA sessions0.81.42.7-1.30.91.21.30.8-1.41.11.10.9-0.81.0-1.0-1.0-1.01.31.41.01.51.3-1.3-1.3-1.6-1.31.5-1.4
Delay discount exponential model param1.21.62.3-1.11.41.41.31.3-1.31.41.41.2-1.31.1-1.1-1.1-1.11.41.31.31.21.4-1.4-0.6-1.5-1.40.9-0.9
Extinction: sum of active levers before priming2.03.04.8-1.71.91.81.81.9-1.61.91.91.9-1.82.0-2.0-2.0-2.01.81.51.81.41.9-1.6-0.8-2.2-2.00.7-0.4
Active lever presses in extinction session 62.62.63.1-1.71.71.71.71.7-1.61.71.71.7-1.81.8-1.8-1.8-1.81.71.51.61.51.7-1.5-1.0-1.8-1.60.9-0.8
Bone: final force1.11.83.01.0-1.4-1.3-1.1-1.51.0-1.6-1.5-1.51.5-1.61.61.61.6-1.1-0.9-1.5-0.4-1.71.5-0.51.71.60.5-0.3
Bone: final moment0.91.42.40.9-1.3-1.2-1.0-1.30.9-1.4-1.3-1.31.3-1.41.41.41.4-1.1-0.9-1.3-0.4-1.51.3-0.41.51.40.3-0.1
Food consumed during 24 hour testing period0.20.40.8-0.70.60.60.70.5-0.70.60.70.5-0.50.7-0.7-0.7-0.70.70.60.60.70.8-0.7-0.5-0.9-0.90.5-0.3
Glucose4.06.48.22.9-2.6-2.8-2.8-2.62.8-2.7-2.7-2.52.6-2.52.52.52.5-2.7-2.7-2.6-2.7-2.52.62.02.32.3-2.11.7
Heart weight1.21.95.5-1.71.11.41.51.1-1.61.21.21.0-1.10.9-0.9-0.9-0.91.71.70.91.90.9-0.9-2.0-0.9-0.91.9-2.3
Delay discount hyperbolic model param1.51.92.7-1.31.51.51.51.4-1.41.51.51.4-1.41.3-1.3-1.3-1.31.51.31.51.31.6-1.5-0.6-1.6-1.50.9-0.9
Intermittent access intake day 1-15 change0.10.31.80.70.0-0.3-0.40.10.5-0.10.00.1-0.20.0-0.0-0.0-0.0-0.2-0.70.1-0.90.0-0.31.3-0.1-0.2-1.31.1
Intermittent access intake escalation0.10.31.90.60.1-0.3-0.30.20.5-0.10.10.1-0.20.1-0.1-0.1-0.1-0.2-0.70.2-0.90.1-0.31.4-0.2-0.3-1.31.1
Intermittent access intake escalation 20.20.42.40.9-0.1-0.5-0.6-0.10.7-0.2-0.2-0.10.0-0.20.20.20.2-0.5-0.90.0-1.1-0.1-0.21.5-0.1-0.1-1.41.3
Intermitt. access day 1 inactive lever presses0.21.94.41.8-1.3-1.5-1.6-1.21.7-1.3-1.2-1.11.0-1.11.11.11.1-1.5-1.9-1.0-1.9-1.10.72.10.80.7-1.91.8
Intermitt. access day 15 inactive lever presses0.31.65.81.5-0.9-1.3-1.4-0.81.5-0.9-0.9-0.80.8-0.80.80.80.8-1.4-1.7-0.7-2.0-0.70.32.40.70.6-2.22.2
Intermitt. access escalation Index0.20.64.2-0.7-0.30.40.4-0.3-0.70.10.0-0.30.4-0.30.30.30.30.61.0-0.21.1-0.0-0.0-1.5-0.3-0.11.9-2.0
Intermittent access day 1 total infusions0.00.10.40.1-0.1-0.2-0.2-0.00.2-0.2-0.2-0.00.1-0.10.10.10.1-0.4-0.2-0.1-0.2-0.30.30.10.60.6-0.20.5
Intermittent access day 15 total infusions0.10.30.6-0.10.70.30.30.7-0.20.40.50.7-0.70.6-0.6-0.6-0.60.2-0.10.7-0.20.4-0.70.7-0.2-0.3-0.70.8
Intermittent access terminal intake (last 3 days)0.40.81.5-0.71.10.90.91.2-0.81.01.01.1-1.11.0-1.0-1.0-1.00.70.61.20.51.0-1.20.0-0.6-0.7-0.00.2
Intermittent access total infusions0.10.10.6-0.00.40.10.10.5-0.10.20.30.4-0.40.4-0.4-0.4-0.4-0.1-0.10.5-0.20.2-0.40.50.1-0.0-0.50.8
Intermittent access day 1 locomotion0.30.61.50.7-0.7-0.8-0.8-0.70.8-0.9-0.8-0.70.8-0.60.60.60.6-0.9-0.7-0.8-0.6-1.01.20.11.11.2-0.50.6
Intermittent access day 15 total locomotion0.10.30.70.6-0.5-0.6-0.6-0.30.6-0.5-0.4-0.30.3-0.30.30.30.3-0.5-0.7-0.5-0.8-0.60.50.70.80.6-0.90.7
Intermittent access total locomotion0.10.10.60.3-0.1-0.3-0.3-0.10.4-0.3-0.2-0.10.1-0.00.00.00.0-0.3-0.5-0.2-0.5-0.30.50.40.50.4-0.80.6
Intermittent access standard deviation0.10.83.10.30.80.20.10.80.20.50.70.8-0.80.8-0.8-0.8-0.80.0-0.50.9-0.80.7-0.71.7-0.7-0.9-1.81.7
Left kidney weight1.19.014.12.4-3.4-3.0-2.8-3.42.6-3.4-3.4-3.43.4-3.43.43.43.4-2.7-2.0-3.7-1.5-3.63.8-0.33.63.60.0-0.2
Right kidney weight1.07.111.42.0-3.0-2.5-2.3-3.12.1-2.9-3.0-3.23.1-3.13.13.13.1-2.3-1.5-3.4-1.0-3.23.4-1.03.23.20.7-0.8
Cocaine induced anxiety0.00.10.50.3-0.1-0.2-0.3-0.10.4-0.1-0.1-0.10.1-0.10.10.10.1-0.2-0.3-0.1-0.40.00.40.6-0.1-0.2-0.60.7
Post-drug Anxiety0.30.41.0-0.70.30.70.70.3-0.60.60.50.3-0.30.2-0.2-0.2-0.20.60.90.20.90.70.0-1.0-0.7-0.71.0-0.7
Baseline Anxiety0.61.02.4-1.10.71.11.10.6-1.11.00.90.6-0.70.6-0.6-0.6-0.61.11.40.61.41.0-0.7-1.5-0.9-0.81.5-1.4
Tail length0.42.113.6-1.1-0.40.60.7-0.5-1.1-0.0-0.3-0.50.6-0.40.40.40.40.81.7-0.72.1-0.50.8-3.70.91.03.3-3.6
Length with tail0.62.513.9-0.6-0.90.20.3-1.0-0.6-0.5-0.8-1.11.1-1.01.01.01.00.41.5-1.41.9-0.91.6-3.71.31.43.4-3.6
Length without tail0.20.85.5-0.90.20.60.70.1-0.80.30.10.0-0.10.0-0.0-0.0-0.00.51.3-0.31.4-0.10.5-2.40.60.72.0-1.7
Times rat made contact with spout1.51.72.71.1-1.6-1.3-1.2-1.61.1-1.5-1.5-1.61.6-1.41.41.41.4-1.2-1.0-1.6-0.6-1.51.6-0.11.31.30.1-0.1
Lifetime Intake0.10.10.7-0.00.40.10.10.4-0.00.20.30.4-0.30.3-0.3-0.3-0.3-0.1-0.10.4-0.20.3-0.30.5-0.1-0.1-0.60.8
Liver weight, left2.13.615.8-2.10.51.71.80.5-2.21.20.90.4-0.40.5-0.5-0.5-0.51.82.80.63.11.0-0.7-4.0-0.9-0.93.9-3.8
Liver weight, right1.83.212.5-2.10.81.71.80.7-2.21.31.10.6-0.70.8-0.8-0.8-0.81.82.60.92.81.0-0.9-3.5-0.9-0.83.5-3.2
Locomotor activity0.00.10.1-0.30.30.30.30.3-0.20.20.20.3-0.30.3-0.3-0.3-0.30.30.30.20.20.1-0.1-0.40.10.10.1-0.2
Locomotor testing distance0.00.10.1-0.30.20.20.20.3-0.10.20.10.3-0.30.3-0.3-0.3-0.30.20.2-0.00.10.00.0-0.30.30.30.1-0.2
Locomotor testing rearing0.20.61.4-0.71.00.70.71.0-0.50.80.81.1-1.11.2-1.2-1.2-1.20.60.50.80.20.7-0.6-0.1-0.3-0.2-0.20.1
Locomotion in novel chamber1.21.67.71.1-0.3-1.1-1.2-0.21.5-0.7-0.6-0.30.2-0.30.30.30.3-1.3-1.9-0.4-2.1-0.50.32.70.50.5-2.82.8
Locomotion in novel chamber post-restriction0.10.40.7-0.60.80.50.50.8-0.40.70.70.8-0.80.8-0.8-0.8-0.80.50.20.70.20.7-0.80.2-0.7-0.8-0.40.5
Fecal boli incidents, locomotor time 10.00.00.1-0.20.10.00.10.10.0-0.1-0.10.1-0.0-0.20.20.20.20.10.1-0.20.2-0.10.2-0.4-0.3-0.30.2-0.3
Change in fecal boli incidents, locomotor task0.40.51.00.8-0.9-0.6-0.6-1.00.5-0.6-0.7-1.00.9-0.90.90.90.9-0.6-0.5-0.5-0.3-0.40.40.30.40.5-0.0-0.0
Time >=10cm from walls, locomotor time 10.30.31.4-0.50.50.40.50.4-0.50.50.60.4-0.60.4-0.4-0.4-0.40.50.30.60.40.6-0.70.0-1.1-1.20.20.0
Bouts of movement, locomotor time 10.10.21.2-0.40.10.30.30.1-0.30.30.40.1-0.10.2-0.2-0.2-0.20.30.30.30.30.6-0.80.1-1.0-1.10.20.1
Total resting periods, locomotor time 10.30.31.9-0.30.20.40.30.2-0.30.50.40.2-0.20.3-0.3-0.3-0.30.40.20.50.20.8-1.10.3-1.3-1.40.10.3
Rest time, locomotor task time 10.20.31.50.6-0.5-0.4-0.4-0.30.4-0.2-0.2-0.30.3-0.20.20.20.2-0.4-0.60.1-0.60.1-0.51.2-0.7-0.6-0.81.2
Distance moved, locomotor task time 10.00.10.2-0.40.40.30.30.3-0.20.30.30.3-0.30.3-0.3-0.3-0.30.30.20.20.20.20.0-0.40.10.00.1-0.3
Vertical activity count, locomotor time 10.10.81.5-1.21.10.90.91.0-0.90.91.01.0-1.11.1-1.1-1.1-1.10.90.80.90.80.7-0.7-0.7-0.1-0.20.5-0.7
Time >=10cm from walls, locomotor time 20.20.71.01.0-1.0-1.0-0.8-1.00.8-1.0-0.9-1.00.8-0.90.90.90.9-0.8-1.0-0.6-0.6-0.90.40.60.30.4-0.40.5
Bouts of movement, locomotor time 20.00.10.20.4-0.2-0.3-0.3-0.40.3-0.2-0.3-0.40.4-0.30.30.30.3-0.4-0.2-0.2-0.2-0.2-0.10.20.10.2-0.00.3
Total resting periods, locomotor time 20.00.00.10.00.10.10.10.0-0.10.10.10.00.00.1-0.1-0.1-0.1-0.00.20.10.10.2-0.3-0.0-0.3-0.10.20.2
Rest time, locomotor task time 20.20.30.8-0.30.30.60.50.5-0.40.70.60.5-0.50.4-0.4-0.4-0.40.40.50.60.30.9-0.80.3-0.9-0.80.00.2
Distance moved, locomotor task time 20.20.20.90.3-0.3-0.5-0.5-0.30.6-0.4-0.3-0.30.1-0.00.00.00.0-0.5-0.7-0.2-0.7-0.50.40.50.70.6-0.91.0
Vertical activity count, locomotor time 20.20.40.80.4-0.7-0.7-0.7-0.70.6-0.8-0.7-0.60.6-0.50.50.50.5-0.6-0.6-0.6-0.6-0.90.50.20.80.8-0.40.2
Light reinforcement 10.00.11.0-0.20.20.00.00.2-0.1-0.0-0.00.2-0.20.3-0.3-0.3-0.3-0.10.10.1-0.0-0.30.1-0.41.01.0-0.00.1
Light reinforcement 21.73.98.31.8-2.0-2.0-2.0-2.01.8-2.2-2.2-2.02.1-2.02.02.02.0-1.9-1.7-2.1-1.5-2.42.20.52.92.9-0.60.4
Bone: marrow area0.20.51.0-0.50.80.60.60.8-0.70.60.70.8-0.70.9-0.9-0.9-0.90.50.51.00.40.5-1.0-0.3-0.4-0.40.10.0
Bone: maximum diameter0.10.20.90.20.40.00.10.4-0.10.20.30.4-0.30.3-0.3-0.3-0.30.1-0.30.7-0.30.4-0.90.8-0.4-0.5-0.70.6
Bone: maximum force1.12.13.31.3-1.6-1.5-1.3-1.61.2-1.7-1.6-1.61.6-1.71.71.71.7-1.3-1.1-1.6-0.7-1.81.6-0.21.71.60.2-0.1
Bone: maximum moment0.91.72.61.2-1.4-1.4-1.2-1.41.2-1.6-1.5-1.41.4-1.51.51.51.5-1.3-1.1-1.5-0.7-1.61.50.01.51.40.00.2
Mean time between licks in bursts0.00.21.5-0.3-0.10.20.3-0.1-0.30.0-0.0-0.10.0-0.20.20.20.20.30.6-0.50.7-0.20.6-1.20.20.21.1-1.2
Mean num. licks in bursts0.10.20.5-0.1-0.3-0.00.1-0.4-0.1-0.1-0.1-0.40.4-0.40.40.40.40.10.1-0.10.50.3-0.4-0.3-0.6-0.70.7-0.7
Cd content in liver1.01.12.1-0.51.11.10.91.2-0.71.31.21.2-1.31.2-1.2-1.2-1.21.00.71.20.31.4-1.10.4-1.4-1.3-0.4-0.1
Co content in liver0.10.10.30.3-0.3-0.3-0.3-0.30.4-0.3-0.3-0.30.3-0.50.50.50.5-0.3-0.3-0.5-0.2-0.20.40.30.10.1-0.20.3
Cu content in liver0.81.01.41.2-1.1-1.1-1.1-1.11.0-1.1-1.1-1.11.1-1.01.01.01.0-1.0-1.1-0.8-1.0-0.90.70.90.80.8-0.70.5
Fe content in liver0.10.21.0-0.2-0.00.20.2-0.2-0.40.0-0.1-0.20.2-0.20.20.20.20.20.50.00.6-0.0-0.1-1.00.10.21.0-0.9
K content in liver0.60.51.60.1-0.6-0.5-0.3-0.70.1-0.7-0.7-0.70.7-0.80.80.80.8-0.2-0.0-0.80.3-1.00.7-0.91.21.10.9-1.3
Mg content in liver0.10.10.4-0.30.50.30.30.4-0.40.20.30.4-0.40.4-0.4-0.4-0.40.40.10.40.20.1-0.60.0-0.0-0.1-0.0-0.3
Mn content in liver0.70.71.6-0.61.00.80.81.0-0.70.90.91.0-1.01.0-1.0-1.0-1.00.70.51.10.41.0-1.20.2-1.0-1.0-0.20.2
Na content in liver2.93.34.41.5-2.0-1.9-1.9-2.11.8-2.0-2.0-2.02.1-1.91.91.91.9-1.9-1.6-2.1-1.4-2.11.90.62.01.9-0.60.8
Rb content in liver4.04.77.8-2.12.42.22.22.4-2.22.32.32.4-2.52.4-2.4-2.4-2.42.31.82.51.62.3-2.8-0.7-2.0-2.10.7-1.1
Se content in liver0.60.71.21.1-0.9-0.9-0.8-0.90.8-0.9-0.9-0.90.9-0.90.90.90.9-0.9-0.8-0.9-0.7-0.90.90.40.70.7-0.40.5
Sr content in liver1.81.52.5-1.11.31.31.21.3-1.11.41.41.3-1.31.3-1.3-1.3-1.31.11.01.50.81.6-1.6-0.1-1.5-1.50.20.1
Zn content in liver0.20.30.9-0.30.20.50.50.1-0.50.50.40.1-0.10.1-0.1-0.1-0.10.50.70.20.80.6-0.4-0.6-1.0-0.90.8-0.7
Bone: minimum diameter0.81.52.31.3-1.4-1.3-1.2-1.41.1-1.3-1.4-1.41.4-1.51.51.51.5-1.2-0.9-1.2-0.8-1.31.10.21.31.3-0.10.1
Time in familiar zone, hab. session 11.31.42.5-0.81.51.11.01.5-0.71.31.31.5-1.61.3-1.3-1.3-1.30.90.51.30.31.5-1.20.6-1.5-1.5-0.50.6
Time in novel zone, hab. session 11.21.32.40.9-1.5-1.1-1.0-1.50.8-1.2-1.3-1.51.6-1.21.21.21.2-0.9-0.6-1.3-0.4-1.31.3-0.51.41.40.4-0.4
Total zone transitions, hab. session 11.52.04.2-1.32.01.31.32.0-1.21.41.52.1-2.02.0-2.0-2.0-2.01.20.91.60.50.9-1.0-0.5-0.2-0.2-0.3-0.0
Total locomotion distance, hab. session 10.50.71.4-0.91.10.90.81.2-0.80.90.91.2-1.21.1-1.1-1.1-1.10.80.80.70.50.5-0.4-0.7-0.1-0.10.1-0.3
Locomotion velocity, hab. session 10.60.81.7-0.91.30.90.91.3-0.81.01.01.3-1.31.2-1.2-1.2-1.20.80.70.90.50.6-0.6-0.5-0.3-0.2-0.0-0.1
Time in familiar zone, hab. session 21.61.93.1-1.41.71.51.41.8-1.21.51.61.8-1.81.7-1.7-1.7-1.71.31.21.20.91.2-0.8-0.8-1.1-1.00.3-0.1
Time in novel zone, hab. session 24.34.77.12.3-2.6-2.3-2.2-2.62.0-2.4-2.5-2.62.7-2.52.52.52.5-2.1-2.0-2.1-1.6-2.11.81.12.01.9-0.60.3
Total zone transitions, hab. session 20.81.11.7-1.31.31.11.11.3-1.11.01.01.3-1.31.3-1.3-1.3-1.31.01.00.80.90.5-0.3-1.20.10.10.6-0.7
Total locomotion distance, hab. session 20.10.10.6-0.40.40.30.30.3-0.30.20.20.3-0.30.2-0.2-0.2-0.20.30.40.00.3-0.10.1-0.80.30.40.3-0.4
Locomotion velocity, hab. session 20.00.10.4-0.30.30.20.20.2-0.20.10.20.2-0.30.1-0.1-0.1-0.10.20.30.00.3-0.10.1-0.70.20.30.3-0.3
Novel to familiar place preference ratio0.10.21.30.30.0-0.2-0.20.00.1-0.00.00.0-0.1-0.20.20.20.2-0.2-0.50.4-0.40.2-0.81.1-0.3-0.4-0.60.7
Novelty place preference0.10.10.50.20.0-0.1-0.10.00.00.00.0-0.0-0.0-0.20.20.20.2-0.1-0.20.3-0.20.3-0.70.7-0.4-0.5-0.30.3
Time in novel zone, NPP test0.10.10.8-0.10.30.20.20.2-0.30.20.20.2-0.30.0-0.0-0.0-0.00.20.00.50.10.4-0.90.4-0.5-0.5-0.00.1
Total zone transitions, NPP test0.91.32.9-1.21.71.11.11.7-0.91.11.21.7-1.71.6-1.6-1.6-1.61.00.90.90.60.5-0.2-0.80.10.10.0-0.3
Total locomotion distance, NPP test0.20.30.8-0.30.80.30.30.9-0.00.40.50.8-0.90.7-0.7-0.7-0.70.10.10.1-0.2-0.10.4-0.20.50.5-0.60.4
Locomotion velocity, NPP test0.20.21.10.20.4-0.1-0.10.50.40.00.10.5-0.50.4-0.4-0.4-0.4-0.3-0.4-0.1-0.7-0.20.60.50.60.6-1.11.0
Intraocular pressure0.30.52.50.20.60.1-0.10.60.20.40.40.7-0.70.7-0.7-0.7-0.7-0.1-0.50.7-0.90.3-0.41.50.00.1-1.61.3
Delta distance traveled before/after self-admin2.32.53.3-1.61.41.71.71.3-1.81.61.61.4-1.31.5-1.5-1.5-1.51.71.71.61.81.7-1.7-1.4-1.7-1.71.5-1.4
Delta ambulatory time before/after self-admin1.52.54.1-1.61.31.71.71.3-1.81.61.61.4-1.31.5-1.5-1.5-1.51.81.71.61.71.7-1.7-1.2-2.0-1.91.4-1.3
Parametrial fat weight7.116.823.8-4.94.04.54.63.8-4.74.24.03.8-3.73.9-3.9-3.9-3.94.44.93.84.83.8-3.5-4.7-2.9-2.94.4-3.9
Pavlov. Cond. lever latency0.20.30.7-0.30.80.50.40.8-0.20.60.60.8-0.80.7-0.7-0.7-0.70.40.20.4-0.10.6-0.20.4-0.5-0.5-0.50.2
Pavlov. Cond. magazine entry latency0.20.31.2-0.5-0.10.40.4-0.1-0.70.30.2-0.10.1-0.10.10.10.10.50.60.50.80.4-1.0-0.7-0.6-0.61.1-1.1
Pavlov. Cond. change in total contacts0.80.81.40.9-1.2-1.0-1.0-1.20.8-1.0-1.0-1.11.2-0.90.90.90.9-0.9-0.8-0.8-0.8-0.90.80.40.80.8-0.40.4
Pavlov. Cond. index score0.20.21.2-0.4-0.20.20.3-0.3-0.50.0-0.1-0.30.3-0.20.20.20.20.20.50.20.80.1-0.5-0.9-0.1-0.21.1-0.9
Pavlov. Cond. latency score0.20.31.6-0.2-0.50.00.1-0.5-0.4-0.2-0.3-0.50.5-0.50.50.50.50.10.5-0.00.7-0.1-0.3-1.10.10.01.3-1.0
Pavlov. Cond. lever contacts0.20.20.50.3-0.7-0.4-0.3-0.70.1-0.5-0.6-0.70.7-0.70.70.70.7-0.4-0.1-0.40.1-0.40.1-0.30.40.40.5-0.2
Pavlov. Cond. magazine entry number0.10.20.80.3-0.1-0.3-0.3-0.10.5-0.3-0.2-0.10.0-0.10.10.10.1-0.3-0.4-0.5-0.5-0.40.90.30.50.5-0.50.6
Pavlov. Cond. intertrial magazine entries0.30.40.9-0.30.90.30.20.9-0.10.40.50.9-0.91.0-1.0-1.0-1.00.0-0.00.5-0.3-0.1-0.10.40.70.7-0.80.8
Pavlov. Cond. lever-magazine prob. diff.0.10.20.9-0.3-0.20.20.3-0.2-0.50.1-0.0-0.20.2-0.10.10.10.10.20.50.30.70.2-0.6-0.7-0.3-0.30.9-0.7
Pavlov. Cond. response bias0.20.20.7-0.40.00.30.4-0.0-0.60.30.2-0.00.00.1-0.1-0.1-0.10.40.50.50.70.4-0.8-0.6-0.3-0.40.8-0.8
Pavlov. Cond. lever latency1.62.24.0-1.61.31.61.61.2-1.61.51.51.2-1.21.1-1.1-1.1-1.11.81.71.31.71.6-1.5-1.2-2.0-2.01.4-1.6
Pavlov. Cond. magazine entry latency1.72.45.21.5-1.5-1.6-1.5-1.51.4-1.7-1.8-1.51.5-1.51.51.51.5-1.5-1.2-1.6-1.1-1.91.90.12.32.3-0.40.1
Pavlov. Cond. change in total contacts0.81.93.71.4-1.3-1.5-1.5-1.31.4-1.6-1.5-1.31.2-1.21.21.21.2-1.5-1.4-1.3-1.3-1.71.60.71.91.9-0.90.8
Pavlov. Cond. index score2.03.15.91.9-1.6-1.9-1.9-1.51.9-1.9-1.9-1.51.5-1.41.41.41.4-2.0-1.9-1.6-1.9-2.12.01.22.42.4-1.41.4
Pavlov. Cond. latency score2.23.56.42.0-1.6-2.0-2.0-1.62.0-2.0-1.9-1.61.6-1.51.51.51.5-2.1-2.1-1.8-2.1-2.22.11.42.52.5-1.61.5
Pavlov. Cond. lever contacts1.01.53.61.2-1.1-1.3-1.3-1.11.2-1.3-1.3-1.11.0-0.90.90.90.9-1.4-1.2-1.1-1.2-1.51.30.61.91.9-0.81.1
Pavlov. Cond. magazine entry number1.92.54.7-1.61.51.71.61.6-1.51.81.81.6-1.51.6-1.6-1.6-1.61.51.41.71.22.0-2.0-0.4-2.2-2.20.6-0.2
Pavlov. Cond. intertrial magazine entries1.63.54.6-2.02.02.01.92.0-1.92.12.12.0-2.02.1-2.1-2.1-2.11.91.82.01.61.9-1.8-0.9-1.8-1.80.9-0.5
Pavlov. Cond. lever-magazine prob. diff.1.92.95.11.9-1.5-1.8-1.8-1.51.8-1.8-1.8-1.41.4-1.41.41.41.4-1.9-1.8-1.6-1.9-2.01.91.22.32.2-1.41.4
Pavlov. Cond. response bias1.72.34.61.6-1.5-1.6-1.6-1.51.5-1.7-1.7-1.51.4-1.41.41.41.4-1.7-1.5-1.5-1.4-1.81.70.72.12.1-0.80.9
Time in closed arm before self-admin1.01.84.0-1.61.01.41.51.1-1.61.21.11.0-1.01.0-1.0-1.0-1.01.41.71.01.81.1-1.1-2.0-1.3-1.11.8-1.7
Time in closed arm after self-admin0.40.40.70.6-0.8-0.7-0.7-0.80.7-0.7-0.8-0.80.7-0.70.70.70.7-0.7-0.6-0.7-0.6-0.70.80.40.60.7-0.40.2
Time in open arm before self-admin3.54.26.22.5-2.1-2.2-2.3-2.12.3-2.1-2.1-2.01.9-2.02.02.02.0-2.3-2.3-2.0-2.3-1.91.92.01.31.7-1.92.1
Time in open arm after self-admin0.50.61.40.7-0.6-0.9-0.8-0.60.9-0.8-0.7-0.60.6-0.60.60.60.6-0.8-1.0-0.7-0.9-0.60.51.00.10.2-0.91.2
Bone: periosteal estimation0.20.50.80.9-0.8-0.8-0.8-0.80.6-0.9-0.8-0.80.8-0.70.70.70.7-0.8-0.7-0.5-0.6-0.80.50.20.80.8-0.20.4
Bone: periosteal perimeter0.00.10.30.4-0.1-0.3-0.3-0.10.3-0.2-0.2-0.10.1-0.20.20.20.2-0.3-0.50.1-0.4-0.1-0.20.60.10.0-0.50.5
Bone: post-yield work0.30.51.9-0.70.50.70.70.5-0.90.60.50.5-0.50.4-0.4-0.4-0.40.80.90.61.00.5-0.8-1.1-0.4-0.51.2-1.4
Progressive ratio test 1 active lever presses0.10.10.70.3-0.0-0.3-0.30.00.3-0.2-0.2-0.00.2-0.10.10.10.1-0.5-0.40.0-0.5-0.30.20.60.60.4-0.60.8
Progressive ratio test 1 breakpoint0.10.10.70.20.1-0.2-0.20.10.3-0.1-0.10.10.10.0-0.0-0.0-0.0-0.4-0.40.1-0.5-0.20.10.70.50.4-0.60.8
Progressive ratio test 1 inactive lever presses0.71.83.21.7-1.3-1.5-1.5-1.21.6-1.3-1.2-1.11.1-1.11.11.11.1-1.5-1.7-1.1-1.7-1.10.91.80.91.0-1.71.8
Progressive ratio test 2 active lever presses0.50.61.3-0.51.00.60.61.1-0.50.80.91.0-1.01.0-1.0-1.0-1.00.40.21.00.00.8-1.20.7-0.6-0.6-0.50.8
Progressive ratio test 2 breakpoint0.50.71.4-0.51.10.70.61.1-0.50.91.01.0-1.01.0-1.0-1.0-1.00.40.21.00.10.9-1.20.6-0.7-0.7-0.50.8
Progressive ratio test 2 inactive lever presses0.10.31.60.4-0.0-0.3-0.30.20.4-0.10.10.1-0.40.1-0.1-0.1-0.1-0.4-0.70.2-0.80.0-0.31.3-0.0-0.1-1.11.2
Incentive Sensitization - Responses0.41.12.0-0.91.21.01.01.3-0.81.21.31.2-1.41.3-1.3-1.3-1.30.90.61.20.41.2-1.40.3-1.1-1.0-0.10.2
Incentive Sensitization - Breakpoint0.41.01.9-0.81.21.00.91.2-0.81.11.21.1-1.31.2-1.2-1.2-1.20.90.61.20.51.2-1.40.2-1.1-1.0-0.10.1
Sum of active levers in priming session hrs 5-62.42.23.7-1.81.31.61.61.1-1.71.41.41.2-1.11.2-1.2-1.2-1.21.71.81.31.91.4-1.4-1.8-1.6-1.41.9-1.8
Progressive ratio0.10.20.9-0.00.3-0.2-0.20.20.2-0.1-0.00.3-0.30.2-0.2-0.2-0.2-0.4-0.60.3-0.6-0.2-0.30.80.60.6-0.91.0
Food seeking constrained by brief footshock0.00.00.10.2-0.1-0.1-0.2-0.10.2-0.1-0.1-0.10.1-0.20.20.20.2-0.2-0.2-0.2-0.2-0.20.20.20.30.3-0.30.3
Seeking ratio, punishment vs. effort0.40.81.60.9-1.1-0.8-0.8-1.10.8-0.9-0.9-1.11.1-1.11.11.11.1-0.6-0.4-1.3-0.4-0.91.2-0.20.60.60.2-0.4
Retroperitoneal fat weight0.10.61.7-0.80.80.80.80.7-0.80.70.60.7-0.80.8-0.8-0.8-0.80.61.00.50.80.3-0.2-1.30.30.40.9-0.6
Reaction time number correct0.00.10.3-0.50.30.30.30.2-0.30.20.30.2-0.20.4-0.4-0.4-0.40.30.30.20.40.1-0.0-0.50.00.00.4-0.1
Reaction time mean minus median0.00.10.80.20.20.0-0.10.20.10.20.20.2-0.20.3-0.3-0.3-0.30.1-0.30.4-0.40.3-0.40.9-0.3-0.3-0.80.4
Reaction time mean minus median AUC0.21.42.3-0.91.31.11.01.4-0.91.31.31.4-1.41.5-1.5-1.5-1.51.10.71.40.41.3-1.30.2-1.3-1.3-0.30.1
Reaction time num false alarms0.30.41.4-0.20.90.20.10.8-0.00.40.50.8-0.90.9-0.9-0.9-0.90.2-0.30.6-0.60.2-0.40.90.20.1-1.21.0
Reaction time num false alarms AUC0.20.41.4-0.10.80.10.10.70.00.30.50.7-0.80.8-0.8-0.8-0.80.2-0.40.6-0.60.1-0.40.90.10.1-1.20.9
Reaction time trials correct on left0.00.10.3-0.50.30.30.30.2-0.30.20.30.2-0.20.4-0.4-0.4-0.40.30.30.20.40.1-0.0-0.50.00.00.4-0.1
Reaction time trials on left0.00.10.2-0.50.30.30.30.2-0.40.20.30.2-0.20.4-0.4-0.4-0.40.30.30.20.40.1-0.1-0.50.0-0.00.4-0.0
Reaction time mean0.00.00.20.3-0.2-0.1-0.2-0.20.1-0.0-0.1-0.20.2-0.10.10.10.10.0-0.20.1-0.30.1-0.30.5-0.3-0.2-0.3-0.2
Reaction time mean AUC0.10.10.80.6-0.3-0.3-0.4-0.30.4-0.2-0.3-0.30.3-0.20.20.20.2-0.2-0.50.0-0.60.0-0.10.9-0.2-0.1-0.70.2
Median of all reaction times0.10.10.20.5-0.4-0.3-0.4-0.50.2-0.3-0.4-0.50.5-0.40.40.40.4-0.2-0.3-0.2-0.3-0.1-0.00.4-0.00.0-0.1-0.3
Reaction time omissions0.10.10.3-0.30.20.30.30.2-0.30.30.30.2-0.30.4-0.4-0.4-0.40.60.30.40.30.4-0.4-0.2-0.5-0.50.0-0.4
Reaction time false alarm rate0.20.31.2-0.10.70.10.10.70.00.30.40.7-0.70.7-0.7-0.7-0.70.2-0.30.5-0.50.2-0.40.9-0.1-0.2-1.10.7
Reaction time premature initiation rate0.60.91.5-1.01.01.01.01.0-0.91.01.11.0-1.01.0-1.0-1.0-1.00.90.80.90.71.1-0.9-0.3-1.2-1.20.4-0.2
Reaction time premature initiations0.31.01.5-1.11.11.11.11.1-1.01.11.21.1-1.11.2-1.2-1.2-1.21.00.91.00.81.1-0.9-0.5-1.1-1.10.4-0.1
Std. dev. reaction times0.10.20.70.10.30.10.00.3-0.10.30.30.3-0.30.4-0.4-0.4-0.40.2-0.20.6-0.30.5-0.70.8-0.6-0.6-0.70.4
Reaction time trials completed0.00.10.2-0.50.30.30.30.2-0.40.20.30.2-0.20.4-0.4-0.4-0.40.30.30.20.40.1-0.1-0.50.0-0.00.4-0.0
Reaction time trials AUC0.00.10.2-0.50.30.30.30.2-0.30.20.30.2-0.20.4-0.4-0.4-0.40.30.30.20.30.1-0.0-0.4-0.0-0.00.3-0.0
Run reversals in cocaine runway, females0.20.21.30.60.3-0.0-0.10.50.30.20.20.4-0.50.3-0.3-0.3-0.3-0.3-0.40.1-0.60.10.10.9-0.10.1-1.01.2
Run reversals in cocaine runway, males0.60.61.0-0.61.00.70.71.0-0.60.90.91.0-1.00.9-0.9-0.9-0.90.70.41.00.20.8-1.00.3-0.7-0.7-0.50.2
Latency to leave start box in cocaine runway0.10.20.60.6-0.5-0.4-0.4-0.60.4-0.5-0.5-0.40.5-0.40.40.40.4-0.5-0.3-0.4-0.3-0.50.40.00.80.6-0.10.1
Latency to leave start box in cocaine runway, F0.10.10.30.3-0.4-0.2-0.1-0.60.1-0.3-0.4-0.40.5-0.40.40.40.4-0.30.0-0.40.2-0.40.4-0.60.60.40.5-0.2
Latency to leave start box in cocaine runway, M0.10.00.20.2-0.2-0.2-0.2-0.10.2-0.2-0.2-0.10.20.0-0.0-0.0-0.0-0.2-0.3-0.0-0.3-0.20.10.40.30.3-0.50.1
Std. dev. time between licks in bursts0.10.30.5-0.60.60.50.50.7-0.50.50.60.7-0.70.6-0.6-0.6-0.60.40.40.70.40.4-0.5-0.2-0.2-0.20.20.1
Total sessions with >9 infusions0.10.20.9-0.00.40.10.10.40.00.20.30.4-0.20.4-0.4-0.4-0.4-0.1-0.20.4-0.30.3-0.20.6-0.3-0.2-0.71.0
Short access day 1 total inactive lever presses0.00.10.5-0.20.30.30.30.3-0.30.30.30.3-0.30.2-0.2-0.2-0.20.20.20.30.30.3-0.6-0.1-0.7-0.40.2-0.0
Short access day 10 total inactive lever presses0.10.91.51.2-1.1-1.1-1.0-0.91.1-1.0-0.9-0.90.8-0.90.90.90.9-1.0-1.2-0.9-1.1-0.80.61.00.20.4-1.11.0
Short access day 1 total infusions0.20.53.20.7-0.2-0.6-0.6-0.10.8-0.4-0.3-0.20.2-0.20.20.20.2-0.8-0.9-0.2-1.0-0.20.21.30.10.2-1.31.8
Short access day 10 total infusions0.10.21.20.20.1-0.2-0.20.20.3-0.00.10.2-0.10.2-0.2-0.2-0.2-0.4-0.50.2-0.6-0.0-0.00.90.40.4-1.01.1
Short access total infusions0.30.42.70.7-0.2-0.5-0.6-0.20.7-0.4-0.3-0.20.3-0.20.20.20.2-0.8-0.8-0.1-0.9-0.30.31.20.30.3-1.21.6
Short access day 1 locomotion1.01.73.11.5-0.9-1.4-1.4-1.01.5-1.3-1.2-1.01.0-1.01.01.01.0-1.5-1.7-0.9-1.6-1.20.91.51.41.3-1.61.8
Short access day 10 total locomotion0.21.02.51.2-0.8-1.1-1.1-0.81.2-1.0-0.9-0.80.9-0.60.60.60.6-1.0-1.3-0.8-1.3-0.91.11.20.60.7-1.61.2
Short access total locomotion1.32.04.21.7-1.0-1.6-1.6-1.11.7-1.4-1.2-1.11.1-1.01.01.01.0-1.6-1.9-1.1-1.9-1.31.31.81.11.1-2.02.0
One hour access (0.3 mA shock)0.91.11.9-0.91.31.01.01.3-1.01.11.21.3-1.21.3-1.3-1.3-1.30.90.71.40.61.1-1.30.1-0.9-1.0-0.00.3
Compulsive drug intake0.40.52.2-0.90.50.70.70.3-0.90.50.40.4-0.30.3-0.3-0.3-0.30.71.00.31.10.5-0.5-1.2-0.5-0.41.5-1.2
One hour access (shock baseline)0.00.10.60.10.2-0.0-0.10.30.10.10.20.2-0.20.3-0.3-0.3-0.3-0.1-0.20.4-0.40.0-0.30.70.2-0.0-0.70.8
Social response proportion1.31.76.1-1.60.81.21.40.6-1.61.00.90.6-0.60.7-0.7-0.7-0.71.51.70.82.00.9-0.9-2.1-0.8-0.92.2-2.5
Social responses1.52.04.6-1.81.11.41.51.0-1.71.21.21.1-0.91.3-1.3-1.3-1.31.81.61.21.71.1-1.3-1.8-0.9-0.91.7-2.2
Social time2.03.24.9-2.21.61.91.91.5-2.21.81.71.6-1.41.6-1.6-1.6-1.62.12.11.82.11.6-1.9-1.8-1.4-1.41.9-2.1
Soleus weight3.08.916.4-3.52.73.23.32.6-3.42.82.82.6-2.52.5-2.5-2.5-2.53.53.72.23.82.4-1.9-4.0-2.2-2.23.8-3.8
Bone: stiffness0.50.93.6-1.00.50.80.90.5-1.10.50.50.5-0.40.4-0.4-0.4-0.41.01.20.51.40.3-0.5-1.9-0.3-0.41.8-1.9
Tibialis anterior weight9.231.839.9-6.16.36.06.06.2-5.96.06.16.2-6.26.1-6.1-6.1-6.15.95.46.05.15.7-5.6-3.6-5.1-5.23.2-2.8
Time to tail flick, vehicle, before self-admin6.27.68.8-2.92.93.03.02.8-2.92.92.92.8-2.82.9-2.9-2.9-2.93.02.92.82.72.8-2.7-2.1-2.9-2.62.0-1.9
Time to tail flick, vehicle, after self-admin0.20.40.7-0.80.70.70.70.7-0.70.70.70.7-0.70.7-0.7-0.7-0.70.70.70.80.60.6-0.8-0.4-0.5-0.30.4-0.5
Time to tail flick, test, before self-admin0.70.71.3-1.00.80.91.00.7-1.00.80.80.7-0.80.7-0.7-0.7-0.70.91.10.71.10.8-0.6-1.1-0.7-0.81.1-1.0
Time to tail flick, test, after self-admin0.10.10.30.3-0.5-0.3-0.3-0.50.3-0.4-0.5-0.50.5-0.50.50.50.5-0.3-0.1-0.4-0.1-0.30.1-0.1-0.10.10.2-0.0
Delta time to tail flick, vehicle, before/after SA1.01.11.71.1-1.0-1.1-1.2-0.91.2-1.0-1.0-0.90.9-0.90.90.90.9-1.1-1.3-0.8-1.3-0.90.71.30.90.9-1.21.1
Delta time to tail flick, test, before/after SA0.20.31.10.6-0.4-0.5-0.6-0.30.6-0.3-0.3-0.30.4-0.30.30.30.3-0.6-0.7-0.2-0.8-0.20.01.0-0.00.1-1.01.0
Tibia length0.41.22.10.4-1.2-0.7-0.5-1.30.2-1.0-1.2-1.31.3-1.41.41.41.4-0.60.0-1.10.4-1.00.9-1.31.11.11.5-1.4
Ambulatory time before self-admin2.16.59.02.4-2.5-2.7-2.7-2.52.7-2.7-2.7-2.62.5-2.72.72.72.7-2.7-2.5-2.7-2.4-2.82.61.53.02.9-1.61.4
Ambulatory time after self-admin0.30.51.00.4-0.9-0.7-0.6-1.00.5-0.8-0.9-1.01.0-0.90.90.90.9-0.6-0.3-0.9-0.1-0.90.7-0.40.80.70.4-0.4
Bone: tissue strength2.62.74.11.5-1.8-1.8-1.7-1.71.6-1.9-1.8-1.71.8-1.71.71.71.7-1.5-1.6-1.8-1.3-2.01.90.82.01.9-0.70.3
Total heroin consumption4.35.06.8-2.52.12.42.52.1-2.62.22.22.1-2.02.1-2.1-2.1-2.12.52.62.22.62.1-2.0-2.2-1.9-1.92.3-2.3
Bone: trabecular number4.48.310.0-3.23.23.23.13.1-3.03.13.03.1-3.13.0-3.0-3.0-3.03.03.12.92.82.8-2.6-2.4-2.5-2.41.9-1.9
Bone: trabecular spacing0.60.91.41.0-1.0-1.1-1.0-0.91.0-1.0-0.9-0.91.0-0.90.90.90.9-0.9-1.2-0.8-1.0-1.00.81.00.80.7-0.80.7
Bone: trabecular thickness0.40.60.7-0.90.90.80.80.8-0.80.80.80.8-0.80.8-0.8-0.8-0.80.80.90.70.80.6-0.7-0.8-0.5-0.50.6-0.7
Bone: trabecular tissue density1.93.44.52.1-2.0-2.0-2.0-1.92.0-1.9-1.9-1.91.9-1.91.91.91.9-1.9-1.9-1.9-1.9-1.71.91.51.51.6-1.31.2
Water consumed over 24 hours0.40.81.50.8-1.2-0.8-0.7-1.20.6-1.0-1.0-1.21.2-1.01.01.01.0-0.7-0.4-1.1-0.2-1.01.1-0.60.90.90.5-0.3
Number of responses in last shaping day1.21.53.91.5-0.9-1.3-1.3-0.81.4-1.2-1.0-0.80.8-0.80.80.80.8-1.5-1.6-0.8-1.6-1.00.71.61.11.1-1.72.0