LOC120094195

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression LOC120094195 0.45 0.2 0.0e+00 0.43 0.43 0.42 0.42 1.2e-43 2.8e-43 6.9e-43 7.7e-43
2 Brain intron excision ratio chr8_79333582_79345088 0.08 0.08 9.4e-07 0.07 0.07 0.08 0.07 2.3e-07 3.7e-07 1.3e-07 3.1e-07
3 Brain intron excision ratio chr8_79333582_79344382 0.03 0.03 5.3e-03 0.02 0.02 0.02 0.02 2.9e-03 7.9e-03 1.2e-02 6.5e-03
4 BLA gene expression LOC120094195 0.14 0.12 6.1e-07 0.12 0.12 0.11 0.11 1.0e-06 1.0e-06 1.3e-06 1.3e-06
5 pVTA mRNA stability LOC120094195 0.08 0.07 1.3e-05 0.05 0.05 0.04 0.05 6.5e-05 8.5e-05 3.2e-04 1.3e-04
6 NAcc gene expression LOC120094195 0.04 0.04 2.0e-06 0.04 0.04 0.04 0.04 9.3e-07 1.4e-06 9.2e-07 1.2e-06
7 Brain alternative TSS XR_010054429.1 0.03 0.03 4.8e-03 0.02 0.02 0.01 0.02 9.1e-03 4.9e-03 1.5e-02 9.4e-03
8 Brain alternative TSS XR_005488280.2 0.03 0.04 4.7e-03 0.02 0.02 0.02 0.02 8.0e-03 5.3e-03 7.1e-03 9.2e-03
9 pVTA intron excision ratio chr8_79333582_79344382 0.07 0.06 3.7e-05 0.05 0.06 0.05 0.05 8.2e-05 3.2e-05 5.3e-05 6.2e-05
10 LHb gene expression LOC120094195 0.73 0.2 1.2e-15 0.35 0.41 0.36 0.37 4.5e-09 9.6e-11 1.4e-09 9.9e-10
11 pVTA gene expression LOC120094195 0.41 0.17 0.0e+00 0.39 0.4 0.41 0.4 2.2e-33 1.6e-34 8.5e-35 2.2e-34
12 RMTg gene expression LOC120094195 0.17 0.16 6.7e-04 0.09 0.11 0.11 0.11 2.4e-03 9.5e-04 9.4e-04 9.3e-04
13 pVTA intron excision ratio chr8_79333582_79345088 0.07 0.07 5.0e-05 0.05 0.05 0.03 0.05 5.5e-05 7.4e-05 1.2e-03 9.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.50.91.3-1.11.1-1.1-1.1-1.1-0.8-0.90.90.90.9-0.90.90.7
Area under the delay curve0.00.10.20.4-0.20.20.20.20.30.3-0.3-0.3-0.20.3-0.2-0.1
BMI with tail7.124.926.05.1-5.15.05.15.14.94.9-4.9-4.9-5.05.1-4.9-5.0
BMI without tail1.79.09.42.9-3.02.93.03.03.03.1-3.1-3.0-3.03.0-3.0-3.1
Body weight4.921.522.04.7-4.74.74.74.74.64.6-4.6-4.6-4.64.6-4.6-4.6
Weight adjusted by age2.57.38.02.8-2.72.72.72.72.82.6-2.6-2.6-2.62.7-2.7-2.8
Bone surface0.00.10.30.1-0.10.20.20.20.40.3-0.3-0.3-0.30.3-0.3-0.5
Bone volume0.00.00.1-0.30.2-0.2-0.2-0.20.0-0.00.00.00.00.00.0-0.2
Breakpoint value in progressive ratio session0.61.11.51.0-1.01.01.11.11.21.1-1.1-1.1-1.01.0-1.1-0.9
Number of licking bursts1.13.53.7-1.71.8-1.8-1.9-1.9-1.9-1.91.91.91.9-1.81.91.9
Context. condit. distance diff. score0.91.11.3-1.11.1-1.1-1.2-1.2-1.1-1.11.11.01.0-1.01.10.9
Locomotion velocity, session 10.40.40.70.8-0.70.80.60.60.50.5-0.5-0.6-0.60.6-0.6-0.6
Locomotion distance, session 10.50.70.8-0.70.8-0.7-0.8-0.8-0.9-0.90.90.90.9-0.90.90.8
Locomotion velocity, session 20.00.00.10.2-0.20.20.10.10.00.1-0.1-0.1-0.10.3-0.1-0.0
Locomotion distance, session 20.00.00.00.1-0.00.20.00.0-0.00.0-0.0-0.0-0.00.0-0.0-0.0
Locomotion velocity, session 30.20.20.2-0.50.4-0.4-0.5-0.5-0.4-0.40.40.40.4-0.40.40.4
Locomotion distance, session 32.63.03.1-1.71.7-1.7-1.7-1.7-1.7-1.81.81.81.8-1.71.81.7
Stereotopy head waving bouts, day 31.11.31.51.2-1.21.21.21.21.11.1-1.1-1.1-1.11.1-1.2-1.1
Stereotopy head waving duration, day 31.31.61.71.3-1.31.31.31.31.31.2-1.2-1.2-1.21.3-1.3-1.1
Locomotion velocity, session 72.52.73.4-1.61.8-1.8-1.7-1.7-1.6-1.61.61.61.6-1.61.71.5
Locomotion distance, session 72.32.93.2-1.71.8-1.8-1.8-1.8-1.7-1.71.71.71.7-1.71.71.6
Stereotopy head waving bouts, day 72.42.83.21.6-1.71.51.81.81.71.7-1.7-1.7-1.71.7-1.7-1.5
Stereotopy head waving duration, day 72.22.73.11.5-1.71.51.81.81.71.7-1.7-1.7-1.61.6-1.7-1.5
Locomotion velocity, session 80.00.00.10.10.1-0.1-0.1-0.1-0.2-0.20.20.20.1-0.00.20.2
Locomotion distance, session 81.11.61.8-1.21.3-1.2-1.3-1.3-1.3-1.31.31.21.2-1.21.31.2
Degree of sensitization distance0.10.10.1-0.20.3-0.3-0.3-0.3-0.2-0.20.20.20.2-0.20.20.1
Degree of sensitization stereotypy1.41.61.81.1-1.31.11.31.31.31.3-1.3-1.3-1.31.3-1.3-1.2
Conditioned locomotion0.10.20.3-0.30.3-0.3-0.4-0.4-0.5-0.40.40.40.4-0.40.40.5
Cocaine response after cond. corrected2.43.54.01.9-1.91.91.91.91.91.9-1.9-1.9-1.92.0-1.8-1.7
Cocaine response after cond. not corrected1.31.92.21.4-1.41.31.41.41.51.4-1.4-1.4-1.41.5-1.3-1.3
Cocaine response before conditioning0.91.11.5-1.21.1-1.2-1.0-1.0-0.9-1.01.01.01.0-1.11.00.9
Saline control response0.00.10.10.3-0.30.30.30.30.30.3-0.3-0.2-0.20.2-0.3-0.1
Bone: connectivity density0.91.41.7-1.21.3-1.3-1.3-1.3-1.0-1.11.11.21.2-1.21.21.0
Bone: cortical apparent density1.01.62.0-1.31.3-1.3-1.3-1.3-1.2-1.21.21.21.3-1.21.31.4
Bone: cortical area0.20.40.5-0.50.6-0.7-0.6-0.6-0.6-0.60.60.60.6-0.50.60.5
Bone: cortical porosity0.91.01.3-1.11.0-1.0-1.0-1.0-1.0-1.01.01.01.0-1.11.01.0
Bone: cortical porosity1.51.61.9-1.41.3-1.3-1.3-1.3-1.3-1.31.31.31.3-1.31.21.1
Bone: cortical thickness2.54.24.9-2.02.0-2.1-2.0-2.0-2.0-2.02.02.02.0-1.92.12.2
Bone: cortical thickness1.21.41.9-1.01.1-1.1-1.2-1.2-1.3-1.21.21.21.2-1.11.31.4
Bone: cortical tissue density0.91.51.9-1.21.2-1.3-1.3-1.3-1.1-1.21.21.21.2-1.11.31.4
Condit. Reinf. active minus inactive responses0.00.00.0-0.20.1-0.1-0.1-0.1-0.1-0.00.00.00.00.00.0-0.2
Condit. Reinf. active-inactive response ratio0.50.50.6-0.80.7-0.7-0.8-0.8-0.7-0.70.70.70.7-0.60.70.6
Condit. Reinf. active responses0.40.50.90.6-0.60.70.60.60.70.8-0.8-0.8-0.80.7-0.7-1.0
Condit. Reinf. inactive responses1.21.51.61.2-1.21.31.21.21.21.2-1.2-1.2-1.21.1-1.3-1.2
Incentive salience index mean0.00.00.0-0.10.2-0.0-0.2-0.2-0.2-0.10.10.10.1-0.10.1-0.1
Condit. Reinf. lever presses0.10.20.2-0.30.4-0.2-0.4-0.4-0.5-0.40.40.40.4-0.50.40.3
Condit. Reinf. active minus inactive responses2.23.33.91.7-1.81.71.81.81.81.8-1.8-1.9-1.91.9-1.8-2.0
Condit. Reinf. active-inactive response ratio0.81.21.51.1-1.11.11.11.11.11.1-1.1-1.1-1.11.2-1.1-1.1
Condit. Reinf. active responses1.11.62.11.2-1.31.21.31.31.21.3-1.3-1.3-1.31.3-1.3-1.4
Condit. Reinf. inactive responses0.00.10.1-0.30.3-0.3-0.2-0.2-0.3-0.30.30.30.3-0.40.20.1
Condit. Reinf. lever presses0.81.11.4-1.21.1-1.2-1.0-1.0-1.1-1.01.01.01.0-1.11.00.9
Condit. Reinf. lever reinforcers received0.71.01.40.9-1.00.91.01.01.01.0-1.0-1.0-1.01.0-1.0-1.2
Conditioned reinforcement - actives0.20.91.31.0-1.01.11.01.00.90.9-0.9-0.9-0.90.9-1.0-0.7
Conditioned reinforcement - inactives0.00.00.0-0.10.10.0-0.2-0.2-0.1-0.20.20.20.1-0.10.10.1
Conditioned locomotion0.00.00.00.1-0.00.1-0.0-0.0-0.00.0-0.0-0.0-0.0-0.0-0.00.0
Patch foraging indifference point 0 sec0.10.30.50.6-0.50.50.50.50.60.6-0.6-0.6-0.60.4-0.6-0.7
Patch foraging indifference point AUC0.00.10.1-0.30.3-0.4-0.3-0.3-0.2-0.20.20.20.2-0.10.30.1
Delay disc. indifference point, 0s delay0.10.10.2-0.20.3-0.3-0.3-0.3-0.4-0.40.40.40.4-0.30.40.3
Delay disc. indifference point, 16s delay0.00.00.00.20.00.0-0.1-0.1-0.0-0.00.00.10.1-0.00.10.2
Delay disc. indifference point, 2s delay0.00.00.10.2-0.10.20.00.00.20.2-0.2-0.2-0.20.2-0.2-0.0
Delay disc. indifference point, 24s delay0.10.10.3-0.20.3-0.3-0.4-0.4-0.3-0.30.30.40.4-0.40.30.5
Delay disc. indifference point, 4s delay0.00.00.00.10.1-0.1-0.2-0.20.20.1-0.1-0.1-0.10.1-0.1-0.0
Delay disc. indifference point, 8s delay0.10.10.20.5-0.30.30.30.30.50.4-0.4-0.4-0.30.4-0.3-0.2
Indifference point function ln k0.20.70.91.0-0.80.90.80.80.80.9-0.9-0.9-0.90.8-0.9-0.7
Indifference point function log k0.20.70.91.0-0.80.90.80.80.80.9-0.9-0.9-0.90.8-0.9-0.7
Patch foraging total patch changes 0 sec0.10.40.60.6-0.50.50.60.60.70.6-0.6-0.6-0.60.4-0.7-0.8
Patch foraging total patch changes 12 sec0.00.00.1-0.20.2-0.3-0.2-0.2-0.0-0.10.10.10.1-0.10.10.0
Patch foraging total patch changes 18 sec0.00.10.20.1-0.30.30.30.30.30.3-0.3-0.3-0.40.3-0.3-0.5
Patch foraging total patch changes 24 sec0.00.00.1-0.20.1-0.1-0.1-0.10.10.0-0.0-0.0-0.0-0.1-0.0-0.3
Patch foraging total patch changes 6 sec0.30.51.20.5-0.50.50.60.60.90.8-0.8-0.8-0.80.6-0.8-1.1
Patch foraging time to switch 0 sec0.41.41.7-1.31.2-1.2-1.2-1.2-1.2-1.21.21.21.2-1.21.11.1
Patch foraging water rate 0 sec0.93.43.81.8-1.81.81.91.92.01.9-1.9-1.9-1.81.9-1.8-1.9
Patch foraging water rate 12 sec1.24.85.52.3-2.32.32.32.32.12.2-2.2-2.2-2.22.1-2.1-2.0
Patch foraging water rate 18 sec0.20.50.50.7-0.60.60.70.70.70.7-0.7-0.7-0.70.6-0.7-0.5
Patch foraging water rate 24 sec0.20.30.40.6-0.50.60.60.60.40.5-0.5-0.5-0.50.5-0.5-0.5
Patch foraging water rate 6 sec1.31.92.21.5-1.41.51.41.41.41.4-1.4-1.4-1.41.4-1.3-1.3
Seeking ratio, delayed vs. immediate footshock0.40.60.80.8-0.70.80.70.70.90.8-0.8-0.8-0.80.8-0.7-0.6
Distance traveled before self-admin0.20.40.60.8-0.70.70.70.70.60.6-0.6-0.6-0.60.6-0.6-0.6
Distance traveled after self-admin1.01.81.81.3-1.41.31.41.41.31.3-1.3-1.3-1.31.3-1.3-1.3
Extensor digitorum longus weight8.332.933.75.8-5.85.75.75.75.75.7-5.7-5.7-5.85.8-5.8-5.8
Bone: elastic displacement0.40.50.70.8-0.70.80.70.70.80.8-0.8-0.7-0.70.8-0.7-0.5
Bone: elastic work0.00.00.0-0.10.1-0.1-0.1-0.1-0.1-0.00.00.00.00.10.10.0
Bone: endosteal estimation1.84.55.82.2-2.12.12.02.02.12.1-2.1-2.1-2.12.2-2.1-2.4
Bone: endosteal perimeter2.56.06.92.5-2.52.42.42.42.42.4-2.4-2.4-2.52.5-2.4-2.6
Epididymis fat weight0.00.00.10.2-0.20.20.20.20.20.2-0.2-0.2-0.20.2-0.1-0.1
Delta time in closed arm before/after self-admin1.71.61.9-1.21.2-1.2-1.2-1.2-1.1-1.31.31.31.3-1.41.31.4
Delta time in open arm before/after self-admin0.20.30.4-0.50.4-0.5-0.4-0.4-0.6-0.50.50.50.5-0.50.50.5
Diff in mean of infusions in LGA sessions1.01.72.31.2-1.31.31.31.31.51.4-1.4-1.3-1.31.3-1.3-1.2
Delay discount exponential model param0.10.20.3-0.60.3-0.4-0.3-0.3-0.5-0.50.50.40.4-0.50.40.2
Extinction: sum of active levers before priming0.40.51.00.7-0.70.70.70.71.00.8-0.8-0.8-0.70.6-0.7-0.8
Active lever presses in extinction session 60.70.71.00.9-0.91.01.01.00.80.8-0.8-0.8-0.80.8-0.9-0.6
Bone: final force0.00.00.10.1-0.10.20.10.10.10.1-0.1-0.1-0.10.2-0.1-0.3
Bone: final moment0.10.10.1-0.40.3-0.3-0.3-0.3-0.3-0.30.30.30.3-0.30.30.1
Food consumed during 24 hour testing period0.81.51.71.2-1.21.31.11.11.21.2-1.2-1.3-1.31.3-1.3-1.2
Glucose0.61.01.11.1-1.01.01.01.01.01.0-1.0-1.0-1.01.0-1.0-0.8
Heart weight1.72.83.31.6-1.71.61.61.61.71.7-1.7-1.7-1.71.8-1.7-1.6
Delay discount hyperbolic model param0.10.10.2-0.40.2-0.2-0.2-0.2-0.4-0.30.30.30.3-0.30.30.1
Intermittent access intake day 1-15 change0.10.30.4-0.60.6-0.5-0.6-0.6-0.6-0.60.60.60.6-0.60.60.3
Intermittent access intake escalation0.00.30.3-0.50.6-0.5-0.5-0.5-0.6-0.60.50.50.5-0.50.50.3
Intermittent access intake escalation 20.10.10.10.3-0.30.40.30.30.30.3-0.3-0.3-0.30.3-0.3-0.3
Intermitt. access day 1 inactive lever presses0.33.63.8-1.81.9-1.8-1.9-1.9-1.9-1.91.91.91.9-1.91.91.8
Intermitt. access day 15 inactive lever presses0.10.50.60.7-0.70.70.70.70.70.7-0.7-0.7-0.70.7-0.8-0.7
Intermitt. access escalation Index0.10.50.60.5-0.60.60.70.70.70.7-0.7-0.7-0.70.7-0.7-0.8
Intermittent access day 1 total infusions0.30.80.9-0.90.9-0.9-0.9-0.9-0.9-0.90.90.90.9-0.90.90.9
Intermittent access day 15 total infusions0.51.21.4-1.11.2-1.1-1.1-1.1-1.1-1.11.11.11.1-1.21.11.0
Intermittent access terminal intake (last 3 days)0.20.30.3-0.50.6-0.5-0.5-0.5-0.5-0.50.50.50.5-0.60.50.5
Intermittent access total infusions0.10.10.2-0.40.4-0.3-0.4-0.4-0.4-0.40.40.40.4-0.40.30.3
Intermittent access day 1 locomotion1.22.32.6-1.51.5-1.5-1.6-1.6-1.5-1.51.51.51.5-1.61.51.4
Intermittent access day 15 total locomotion0.41.41.6-1.11.2-1.1-1.2-1.2-1.3-1.21.21.21.2-1.31.21.2
Intermittent access total locomotion0.10.10.10.3-0.20.30.20.20.20.3-0.3-0.3-0.30.2-0.3-0.3
Intermittent access standard deviation0.00.10.3-0.20.4-0.2-0.4-0.4-0.4-0.40.40.40.4-0.40.40.5
Left kidney weight1.29.910.53.2-3.23.23.23.23.13.2-3.2-3.2-3.23.1-3.2-3.0
Right kidney weight1.912.913.43.6-3.63.73.63.63.63.6-3.6-3.6-3.63.6-3.6-3.4
Cocaine induced anxiety0.00.00.1-0.20.2-0.2-0.2-0.2-0.1-0.10.10.10.1-0.20.10.3
Post-drug Anxiety2.12.42.6-1.61.6-1.6-1.6-1.6-1.5-1.51.51.51.5-1.51.51.5
Baseline Anxiety0.81.41.5-1.21.2-1.2-1.1-1.1-1.2-1.21.21.21.2-1.21.21.1
Tail length0.00.00.1-0.00.0-0.0-0.0-0.00.30.2-0.2-0.2-0.10.1-0.2-0.0
Length with tail0.52.32.61.5-1.51.51.51.51.61.6-1.6-1.5-1.51.4-1.6-1.4
Length without tail2.010.811.33.3-3.33.43.33.33.23.2-3.2-3.3-3.33.3-3.3-3.2
Times rat made contact with spout0.10.20.3-0.30.4-0.3-0.5-0.5-0.4-0.40.40.40.4-0.30.40.5
Lifetime Intake0.10.20.2-0.40.4-0.4-0.5-0.5-0.4-0.40.40.40.4-0.40.40.3
Liver weight, left3.15.45.82.3-2.32.22.32.32.42.4-2.4-2.3-2.32.3-2.3-2.4
Liver weight, right0.50.81.11.0-1.01.00.90.90.80.9-0.9-0.9-0.91.0-0.8-0.9
Locomotor activity7.211.211.93.4-3.43.43.43.43.33.3-3.3-3.3-3.43.3-3.4-3.2
Locomotor testing distance3.38.08.42.9-2.92.92.92.92.82.8-2.8-2.8-2.82.7-2.8-2.7
Locomotor testing rearing1.24.44.92.0-2.02.12.12.12.12.1-2.1-2.1-2.12.0-2.1-2.2
Locomotion in novel chamber0.10.10.2-0.40.4-0.3-0.4-0.4-0.2-0.30.30.30.4-0.50.40.4
Locomotion in novel chamber post-restriction0.20.70.9-0.90.9-0.9-1.0-1.0-0.7-0.80.80.80.8-0.70.90.6
Fecal boli incidents, locomotor time 10.00.00.10.00.0-0.0-0.1-0.10.10.0-0.0-0.00.00.00.10.3
Change in fecal boli incidents, locomotor task0.00.00.0-0.10.1-0.1-0.0-0.0-0.2-0.10.10.10.1-0.20.20.1
Time >=10cm from walls, locomotor time 10.20.20.30.5-0.50.50.60.60.50.4-0.4-0.4-0.40.5-0.3-0.4
Bouts of movement, locomotor time 10.10.10.30.5-0.40.40.40.40.20.1-0.1-0.1-0.10.1-0.1-0.2
Total resting periods, locomotor time 10.10.10.20.5-0.40.40.40.40.20.1-0.1-0.2-0.20.2-0.2-0.4
Rest time, locomotor task time 10.00.00.00.1-0.00.00.00.00.0-0.10.10.10.1-0.00.1-0.1
Distance moved, locomotor task time 10.00.10.2-0.40.4-0.3-0.4-0.4-0.4-0.30.30.30.3-0.40.30.3
Vertical activity count, locomotor time 10.00.10.2-0.40.3-0.3-0.3-0.3-0.4-0.30.30.30.3-0.30.20.4
Time >=10cm from walls, locomotor time 20.00.00.1-0.30.2-0.2-0.1-0.1-0.2-0.20.20.20.2-0.10.30.1
Bouts of movement, locomotor time 20.82.64.21.8-1.71.71.71.71.41.4-1.4-1.5-1.51.6-1.5-2.0
Total resting periods, locomotor time 20.72.94.31.9-1.81.81.81.81.51.5-1.5-1.6-1.61.6-1.6-2.1
Rest time, locomotor task time 20.10.20.5-0.20.3-0.3-0.3-0.3-0.5-0.50.50.50.5-0.50.50.7
Distance moved, locomotor task time 20.10.10.2-0.40.3-0.3-0.4-0.4-0.4-0.30.30.30.2-0.20.20.0
Vertical activity count, locomotor time 20.10.20.4-0.60.5-0.5-0.5-0.5-0.5-0.50.50.50.4-0.40.40.2
Light reinforcement 11.04.54.92.1-2.12.12.12.12.22.1-2.1-2.1-2.12.2-2.1-2.0
Light reinforcement 20.20.40.5-0.60.7-0.7-0.6-0.6-0.5-0.60.60.60.7-0.70.70.6
Bone: marrow area1.84.45.72.1-2.12.12.02.02.02.1-2.1-2.1-2.12.1-2.1-2.4
Bone: maximum diameter1.32.63.11.8-1.61.61.51.51.51.6-1.6-1.6-1.61.7-1.6-1.7
Bone: maximum force0.00.10.10.2-0.30.20.20.20.20.2-0.2-0.2-0.20.3-0.2-0.3
Bone: maximum moment0.00.00.1-0.20.1-0.1-0.1-0.1-0.2-0.20.20.10.1-0.10.10.1
Mean time between licks in bursts0.10.40.5-0.50.6-0.6-0.6-0.6-0.7-0.70.70.70.6-0.60.60.7
Mean num. licks in bursts0.82.12.31.4-1.41.51.41.41.51.5-1.5-1.5-1.51.5-1.4-1.4
Cd content in liver1.11.21.3-1.11.1-1.1-1.1-1.1-1.1-1.11.11.11.1-1.11.11.0
Co content in liver1.31.51.6-1.21.2-1.2-1.3-1.3-1.2-1.21.21.21.2-1.11.31.3
Cu content in liver0.10.10.2-0.20.3-0.3-0.3-0.3-0.5-0.40.40.40.4-0.40.30.4
Fe content in liver0.20.20.30.4-0.50.50.40.40.40.4-0.4-0.4-0.50.5-0.4-0.6
K content in liver1.41.41.51.2-1.21.11.21.21.21.2-1.2-1.2-1.21.2-1.2-0.9
Mg content in liver1.41.51.71.3-1.31.21.21.21.21.2-1.2-1.2-1.21.2-1.2-1.1
Mn content in liver0.00.10.2-0.10.2-0.2-0.2-0.2-0.2-0.20.20.20.2-0.20.30.5
Na content in liver6.16.97.52.6-2.62.52.52.52.72.7-2.7-2.7-2.72.7-2.6-2.7
Rb content in liver0.60.70.90.9-0.90.90.90.90.80.8-0.8-0.8-0.80.9-0.9-0.8
Se content in liver0.00.00.1-0.20.1-0.2-0.2-0.2-0.0-0.10.10.10.1-0.00.1-0.0
Sr content in liver0.10.00.1-0.30.2-0.3-0.3-0.3-0.2-0.20.20.20.2-0.10.20.1
Zn content in liver0.00.00.00.2-0.10.10.10.1-0.00.0-0.0-0.1-0.10.0-0.1-0.1
Bone: minimum diameter0.00.10.2-0.40.3-0.4-0.2-0.2-0.1-0.20.20.20.2-0.20.20.0
Time in familiar zone, hab. session 10.10.10.3-0.50.3-0.5-0.3-0.3-0.3-0.20.20.20.3-0.30.20.2
Time in novel zone, hab. session 10.00.00.00.10.00.1-0.1-0.1-0.1-0.20.20.10.1-0.00.20.2
Total zone transitions, hab. session 10.91.31.4-1.11.1-1.0-1.2-1.2-1.2-1.11.11.11.1-1.11.21.1
Total locomotion distance, hab. session 10.10.20.3-0.30.4-0.3-0.5-0.5-0.4-0.50.50.40.4-0.40.50.2
Locomotion velocity, hab. session 10.00.00.00.00.10.0-0.2-0.2-0.1-0.10.10.10.1-0.10.1-0.1
Time in familiar zone, hab. session 20.10.20.3-0.50.3-0.5-0.3-0.3-0.4-0.40.40.40.4-0.40.40.5
Time in novel zone, hab. session 20.00.00.00.2-0.00.2-0.0-0.00.10.1-0.1-0.1-0.10.0-0.0-0.1
Total zone transitions, hab. session 20.00.00.10.2-0.20.30.10.10.00.1-0.1-0.1-0.10.1-0.1-0.1
Total locomotion distance, hab. session 20.40.60.80.9-0.80.90.70.70.70.7-0.7-0.7-0.70.8-0.7-0.8
Locomotion velocity, hab. session 20.10.20.30.6-0.50.60.40.40.40.4-0.4-0.4-0.40.4-0.4-0.5
Novel to familiar place preference ratio1.31.72.11.1-1.21.11.31.31.41.4-1.4-1.4-1.41.3-1.4-1.5
Novelty place preference1.31.72.11.1-1.21.11.31.31.31.4-1.4-1.3-1.31.3-1.4-1.4
Time in novel zone, NPP test1.62.02.51.2-1.31.21.41.41.51.5-1.5-1.5-1.51.4-1.5-1.6
Total zone transitions, NPP test0.10.20.30.5-0.40.50.40.40.30.4-0.4-0.4-0.40.3-0.4-0.4
Total locomotion distance, NPP test0.60.81.01.0-0.81.00.80.80.80.8-0.8-0.9-0.90.9-0.8-1.0
Locomotion velocity, NPP test0.20.30.50.7-0.50.70.50.50.50.5-0.5-0.5-0.50.5-0.5-0.7
Intraocular pressure0.00.00.20.00.1-0.0-0.1-0.10.10.0-0.0-0.0-0.00.20.0-0.4
Delta distance traveled before/after self-admin0.50.60.70.7-0.70.70.80.80.70.8-0.8-0.8-0.80.8-0.8-0.8
Delta ambulatory time before/after self-admin0.10.20.20.3-0.40.40.40.40.20.4-0.4-0.5-0.50.4-0.5-0.4
Parametrial fat weight1.63.84.6-1.81.9-1.9-2.0-2.0-2.0-2.02.02.02.0-1.82.12.1
Pavlov. Cond. lever latency0.10.10.2-0.30.3-0.4-0.3-0.3-0.3-0.30.30.30.3-0.30.30.4
Pavlov. Cond. magazine entry latency0.91.21.3-1.01.1-1.1-1.1-1.1-1.1-1.11.11.11.1-1.11.11.0
Pavlov. Cond. change in total contacts0.00.00.10.2-0.20.20.10.10.10.1-0.1-0.1-0.10.2-0.1-0.2
Pavlov. Cond. index score0.60.80.9-0.80.9-0.8-0.9-0.9-0.9-0.90.90.90.9-0.90.90.9
Pavlov. Cond. latency score0.30.30.4-0.60.6-0.5-0.6-0.6-0.6-0.60.60.60.6-0.60.60.5
Pavlov. Cond. lever contacts0.00.00.0-0.20.1-0.1-0.2-0.2-0.2-0.10.10.10.1-0.10.20.1
Pavlov. Cond. magazine entry number1.21.51.61.2-1.21.21.21.21.21.2-1.3-1.2-1.21.2-1.2-1.2
Pavlov. Cond. intertrial magazine entries0.00.10.10.0-0.20.20.30.30.30.3-0.3-0.3-0.30.2-0.3-0.2
Pavlov. Cond. lever-magazine prob. diff.0.40.50.5-0.60.7-0.6-0.7-0.7-0.7-0.70.70.70.7-0.70.70.7
Pavlov. Cond. response bias0.40.60.6-0.70.7-0.7-0.8-0.8-0.7-0.80.80.80.8-0.80.80.7
Pavlov. Cond. lever latency0.40.60.80.9-0.80.90.70.70.80.8-0.8-0.8-0.80.8-0.7-0.6
Pavlov. Cond. magazine entry latency3.24.65.1-2.12.1-2.2-2.1-2.1-2.2-2.12.12.12.1-2.12.12.3
Pavlov. Cond. change in total contacts0.30.70.8-0.90.8-0.9-0.8-0.8-0.9-0.80.80.80.8-0.80.80.8
Pavlov. Cond. index score1.11.72.0-1.41.3-1.4-1.2-1.2-1.4-1.31.31.31.3-1.31.21.2
Pavlov. Cond. latency score0.71.01.2-1.11.0-1.1-1.0-1.0-1.1-1.01.01.01.0-1.01.01.0
Pavlov. Cond. lever contacts0.40.60.7-0.80.8-0.8-0.7-0.7-0.8-0.80.80.70.7-0.80.70.5
Pavlov. Cond. magazine entry number4.15.35.82.4-2.32.42.32.32.42.3-2.3-2.3-2.32.3-2.3-2.3
Pavlov. Cond. intertrial magazine entries0.61.31.71.1-1.11.01.11.11.31.2-1.2-1.2-1.11.1-1.1-1.2
Pavlov. Cond. lever-magazine prob. diff.1.32.02.3-1.51.4-1.5-1.3-1.3-1.5-1.41.41.41.4-1.41.41.3
Pavlov. Cond. response bias1.72.42.7-1.71.6-1.6-1.5-1.5-1.6-1.51.51.51.5-1.61.51.4
Time in closed arm before self-admin0.00.10.20.3-0.30.40.30.3-0.10.1-0.1-0.1-0.20.2-0.20.1
Time in closed arm after self-admin0.40.41.2-0.60.5-0.5-0.5-0.5-0.7-0.60.60.70.7-0.70.71.1
Time in open arm before self-admin0.50.61.10.6-0.60.50.70.71.00.8-0.8-0.8-0.80.7-0.8-1.0
Time in open arm after self-admin0.20.20.50.4-0.40.40.50.50.50.5-0.5-0.5-0.50.5-0.5-0.7
Bone: periosteal estimation0.61.52.01.3-1.21.11.21.21.21.2-1.2-1.2-1.21.3-1.2-1.4
Bone: periosteal perimeter1.12.22.61.5-1.51.41.41.41.51.5-1.5-1.5-1.51.6-1.5-1.6
Bone: post-yield work0.00.10.10.2-0.40.30.40.40.10.2-0.2-0.2-0.30.2-0.3-0.2
Progressive ratio test 1 active lever presses0.10.10.2-0.30.3-0.3-0.4-0.4-0.3-0.30.30.30.3-0.30.30.2
Progressive ratio test 1 breakpoint0.10.10.2-0.40.4-0.3-0.5-0.5-0.4-0.40.40.40.4-0.40.40.3
Progressive ratio test 1 inactive lever presses1.53.94.2-2.02.0-2.0-2.1-2.1-2.0-2.02.02.02.0-1.92.01.7
Progressive ratio test 2 active lever presses0.30.40.60.5-0.50.60.50.50.60.6-0.6-0.6-0.60.6-0.6-0.7
Progressive ratio test 2 breakpoint0.20.30.50.5-0.50.60.50.50.60.6-0.6-0.6-0.60.6-0.6-0.7
Progressive ratio test 2 inactive lever presses0.00.10.1-0.10.3-0.2-0.3-0.3-0.2-0.20.20.20.2-0.20.2-0.0
Incentive Sensitization - Responses0.20.60.70.6-0.70.70.80.80.80.8-0.8-0.8-0.80.8-0.8-0.8
Incentive Sensitization - Breakpoint0.20.40.50.5-0.60.60.70.70.70.7-0.7-0.7-0.70.7-0.7-0.7
Sum of active levers in priming session hrs 5-60.20.20.30.3-0.40.40.50.50.50.5-0.5-0.5-0.50.5-0.5-0.5
Progressive ratio0.10.30.7-0.30.5-0.4-0.5-0.5-0.8-0.80.80.70.6-0.60.50.4
Food seeking constrained by brief footshock0.20.20.30.5-0.50.50.50.50.50.4-0.4-0.4-0.30.4-0.5-0.3
Seeking ratio, punishment vs. effort1.43.04.01.6-1.71.61.71.72.01.9-1.9-1.8-1.81.8-1.7-1.5
Retroperitoneal fat weight0.10.60.9-0.60.7-0.7-0.8-0.8-0.8-0.80.80.80.8-0.60.90.9
Reaction time number correct0.72.42.61.6-1.51.61.61.61.51.5-1.5-1.5-1.51.5-1.5-1.5
Reaction time mean minus median0.00.10.2-0.10.2-0.3-0.2-0.2-0.4-0.30.30.30.3-0.40.20.1
Reaction time mean minus median AUC0.10.91.2-0.80.9-1.0-0.8-0.8-1.1-1.01.01.00.9-1.00.90.8
Reaction time num false alarms0.81.31.6-1.11.1-1.1-1.2-1.2-1.1-1.21.21.21.2-1.11.21.3
Reaction time num false alarms AUC0.30.71.2-0.80.8-0.8-0.8-0.8-0.9-0.90.90.90.8-0.80.81.1
Reaction time trials correct on left0.72.42.61.6-1.51.61.61.61.51.5-1.5-1.5-1.51.5-1.5-1.5
Reaction time trials on left0.72.52.81.7-1.61.61.61.61.51.6-1.6-1.6-1.61.6-1.5-1.6
Reaction time mean1.84.04.5-2.02.0-2.1-2.0-2.0-2.1-2.02.02.02.0-2.02.01.8
Reaction time mean AUC1.22.83.2-1.61.7-1.8-1.7-1.7-1.8-1.71.71.71.6-1.71.61.4
Median of all reaction times4.46.97.4-2.62.7-2.7-2.7-2.7-2.7-2.62.62.62.6-2.62.62.4
Reaction time omissions0.10.20.30.5-0.40.40.40.40.40.4-0.4-0.4-0.40.3-0.4-0.4
Reaction time false alarm rate2.02.83.4-1.61.6-1.6-1.7-1.7-1.7-1.71.71.71.7-1.61.61.8
Reaction time premature initiation rate1.32.02.51.6-1.41.61.31.31.51.4-1.4-1.4-1.41.3-1.4-1.2
Reaction time premature initiations1.23.54.32.1-1.92.11.81.81.91.9-1.9-1.8-1.81.8-1.8-1.7
Std. dev. reaction times0.41.31.7-1.01.1-1.2-1.1-1.1-1.3-1.21.21.21.1-1.21.11.0
Reaction time trials completed0.72.52.81.7-1.61.61.61.61.51.6-1.6-1.6-1.61.6-1.5-1.6
Reaction time trials AUC0.62.12.31.5-1.51.51.51.51.41.4-1.4-1.4-1.41.4-1.4-1.5
Run reversals in cocaine runway, females0.00.10.3-0.20.2-0.2-0.2-0.20.1-0.10.10.20.2-0.20.30.5
Run reversals in cocaine runway, males0.00.00.00.1-0.10.20.20.2-0.1-0.00.00.0-0.00.10.00.0
Latency to leave start box in cocaine runway2.94.04.22.0-2.02.02.02.02.02.1-2.1-2.0-2.01.9-2.0-1.9
Latency to leave start box in cocaine runway, F1.11.41.61.2-1.21.21.21.21.21.2-1.2-1.2-1.21.1-1.1-1.3
Latency to leave start box in cocaine runway, M6.66.37.02.7-2.62.62.62.62.52.5-2.5-2.5-2.52.4-2.7-2.0
Std. dev. time between licks in bursts0.10.20.30.4-0.40.30.50.50.50.5-0.5-0.5-0.50.4-0.5-0.6
Total sessions with >9 infusions0.40.40.5-0.70.6-0.6-0.7-0.7-0.7-0.70.70.70.7-0.60.70.5
Short access day 1 total inactive lever presses0.40.81.0-1.00.9-0.9-1.0-1.0-0.9-0.90.90.90.9-0.80.90.6
Short access day 10 total inactive lever presses0.10.80.9-0.90.9-1.0-0.8-0.8-1.0-0.90.90.90.9-0.90.90.8
Short access day 1 total infusions0.00.10.1-0.30.3-0.3-0.4-0.4-0.3-0.30.30.30.3-0.30.30.2
Short access day 10 total infusions1.01.71.8-1.31.3-1.3-1.4-1.4-1.3-1.31.31.31.3-1.31.31.1
Short access total infusions0.50.80.9-0.90.9-0.8-0.9-0.9-0.8-0.90.90.90.9-0.90.90.8
Short access day 1 locomotion0.10.10.2-0.40.4-0.4-0.5-0.5-0.3-0.30.30.30.3-0.30.30.1
Short access day 10 total locomotion0.20.60.7-0.70.8-0.8-0.8-0.8-0.8-0.80.80.80.8-0.90.80.8
Short access total locomotion0.40.60.7-0.70.7-0.7-0.8-0.8-0.8-0.80.80.80.8-0.80.80.8
One hour access (0.3 mA shock)0.91.11.41.1-1.11.21.11.11.01.0-1.0-1.0-1.01.0-1.0-0.8
Compulsive drug intake0.71.01.20.9-1.11.01.01.01.01.0-1.0-1.0-1.01.0-1.0-0.7
One hour access (shock baseline)0.00.10.1-0.20.3-0.2-0.2-0.2-0.2-0.20.20.20.2-0.30.20.2
Social response proportion0.00.00.1-0.20.1-0.1-0.1-0.1-0.1-0.10.10.10.1-0.20.10.3
Social responses0.00.00.00.1-0.10.20.20.20.10.2-0.2-0.1-0.1-0.0-0.10.0
Social time0.10.10.10.4-0.30.40.30.30.40.4-0.4-0.3-0.30.2-0.4-0.1
Soleus weight16.849.552.27.0-7.07.07.07.07.07.0-7.1-7.1-7.17.0-7.1-7.2
Bone: stiffness0.50.81.00.7-0.90.90.90.90.90.9-0.9-0.9-0.90.9-0.9-1.0
Tibialis anterior weight13.245.446.56.7-6.86.76.76.76.76.7-6.7-6.7-6.86.8-6.7-6.8
Time to tail flick, vehicle, before self-admin0.30.40.7-0.50.6-0.4-0.5-0.5-0.7-0.70.70.70.6-0.60.60.8
Time to tail flick, vehicle, after self-admin0.10.30.5-0.30.4-0.3-0.4-0.4-0.7-0.60.60.60.5-0.50.50.6
Time to tail flick, test, before self-admin2.32.72.8-1.71.6-1.6-1.6-1.6-1.6-1.71.71.71.7-1.61.61.6
Time to tail flick, test, after self-admin1.11.21.5-1.11.0-1.0-0.9-0.9-1.2-1.11.11.11.1-1.11.01.2
Delta time to tail flick, vehicle, before/after SA0.20.20.3-0.40.4-0.4-0.4-0.4-0.6-0.50.50.50.4-0.50.40.3
Delta time to tail flick, test, before/after SA0.40.50.70.8-0.70.80.80.80.50.6-0.6-0.6-0.70.6-0.6-0.5
Tibia length0.00.00.1-0.30.2-0.2-0.3-0.3-0.2-0.20.20.20.2-0.20.20.2
Ambulatory time before self-admin0.00.00.10.3-0.20.20.20.20.20.1-0.1-0.1-0.10.2-0.1-0.2
Ambulatory time after self-admin0.30.60.60.8-0.80.80.80.80.60.7-0.7-0.7-0.80.7-0.7-0.8
Bone: tissue strength1.41.51.7-1.31.2-1.2-1.2-1.2-1.2-1.21.21.21.2-1.21.21.3
Total heroin consumption2.22.62.81.5-1.61.51.71.71.61.6-1.6-1.6-1.61.6-1.6-1.5
Bone: trabecular number1.42.53.0-1.71.7-1.7-1.7-1.7-1.5-1.51.51.61.6-1.51.61.4
Bone: trabecular spacing0.00.10.10.3-0.30.30.30.30.10.2-0.2-0.2-0.20.2-0.3-0.2
Bone: trabecular thickness0.60.91.1-0.91.0-1.0-1.1-1.1-0.8-0.90.90.90.9-0.81.00.9
Bone: trabecular tissue density3.05.25.72.4-2.32.32.32.32.22.3-2.3-2.3-2.32.3-2.3-2.0
Water consumed over 24 hours0.10.20.3-0.40.4-0.4-0.5-0.5-0.4-0.40.40.40.4-0.40.50.5
Number of responses in last shaping day0.10.20.40.5-0.30.40.30.30.30.3-0.3-0.4-0.40.3-0.4-0.7