Hub : Genes

Aldh3b3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Aldh3b3 0.57 0.18 1.3e-08 0.2 0.28 0.32 0.31 1.4e-05 2.0e-07 1.9e-08 3.5e-08
2 OFC isoform ratio XM_039101315.2 0.2 0.14 6.3e-03 0.05 0.09 0.12 0.09 2.5e-02 4.6e-03 8.3e-04 3.3e-03
3 OFC isoform ratio XM_039101314.2 0.2 0.14 7.7e-03 0.04 0.08 0.13 0.09 3.2e-02 6.0e-03 6.6e-04 4.8e-03
4 NAcc isoform ratio XM_039101314.2 0.05 0.04 2.2e-05 0.04 0.04 0.04 0.04 1.5e-06 2.3e-06 1.6e-06 1.9e-06
5 PL isoform ratio XM_039101315.2 0.09 0.06 2.9e-07 0.06 0.07 0.06 0.07 5.4e-07 8.3e-08 1.8e-07 8.6e-08
6 PL isoform ratio XM_039101314.2 0.09 0.06 3.7e-07 0.06 0.07 0.06 0.07 8.1e-07 1.0e-07 2.5e-07 1.1e-07
7 NAcc gene expression Aldh3b3 0.07 0.05 4.3e-08 0.04 0.06 0.05 0.06 1.7e-07 4.1e-09 1.6e-08 6.7e-09
8 OFC intron excision ratio chr1_210644761_210646067 0.3 0.17 3.8e-04 0.08 0.11 0.13 0.13 6.0e-03 1.3e-03 4.7e-04 6.9e-04
9 OFC intron excision ratio chr1_210661540_210662846 0.3 0.17 4.0e-04 0.08 0.11 0.13 0.12 6.3e-03 1.4e-03 5.0e-04 7.5e-04
10 OFC intron excision ratio chr1_210627982_210629288 0.3 0.17 3.3e-04 0.08 0.12 0.14 0.13 5.0e-03 1.0e-03 4.1e-04 5.1e-04
11 PL gene expression Aldh3b3 0.48 0.16 0.0e+00 0.26 0.45 0.45 0.45 1.1e-28 6.4e-54 1.1e-53 1.3e-53
12 BLA gene expression Aldh3b3 0.4 0.16 0.0e+00 0.2 0.31 0.32 0.31 6.6e-11 1.1e-16 8.0e-18 4.1e-17
13 OFC intron excision ratio chr1_210678203_210679509 0.3 0.17 3.8e-04 0.08 0.11 0.07 0.12 6.8e-03 1.4e-03 9.5e-03 8.0e-04
14 IC gene expression Aldh3b3 0.59 0.16 0.0e+00 0.33 0.35 0.34 0.32 2.7e-14 1.2e-15 3.2e-15 6.7e-14
15 IC isoform ratio XM_039101314.2 0.25 0.14 6.9e-06 0.05 0.07 0.07 0.07 4.1e-03 8.6e-04 9.4e-04 8.6e-04
16 Brain intron excision ratio chr1_210624747_210625093 0.04 0.03 2.4e-03 0.01 0.02 0.02 0.01 6.4e-02 6.8e-03 8.9e-03 2.8e-02
17 Brain intron excision ratio chr1_210624747_210625152 0.04 0.03 2.7e-03 0.01 0.02 0.02 0.01 6.8e-02 8.4e-03 1.1e-02 3.9e-02
18 Brain gene expression Aldh3b3 0.31 0.15 0.0e+00 0.16 0.21 0.22 0.21 8.2e-15 3.2e-19 5.5e-20 1.4e-19
19 IL gene expression Aldh3b3 0.43 0.19 9.7e-06 0.11 0.18 0.2 0.21 1.4e-03 3.6e-05 1.3e-05 9.9e-06
20 pVTA gene expression Aldh3b3 0.04 0.03 2.4e-03 0.04 0.02 0.01 0.02 4.5e-04 1.2e-02 3.0e-02 4.3e-03
21 IC isoform ratio XM_039101315.2 0.26 0.15 4.8e-06 0.08 0.07 0.06 0.07 2.3e-04 7.7e-04 1.2e-03 6.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density2.54.37.4-1.20.6-0.5-0.52.1-2.1-2.1-2.0-2.0-2.0-2.2-1.8-2.2-2.4-2.52.5-2.5-2.2-2.7-2.72.4
Area under the delay curve0.50.51.3-0.20.5-0.5-0.00.6-0.6-0.6-0.6-0.6-0.6-0.7-0.6-0.7-0.9-0.90.9-0.9-0.8-1.0-1.11.0
BMI with tail3.311.413.7-2.83.3-3.3-2.13.4-3.4-3.4-3.4-3.4-3.4-3.5-3.2-3.5-3.6-3.63.6-3.6-3.7-3.3-3.43.6
BMI without tail1.95.76.4-2.52.4-2.5-2.02.5-2.5-2.5-2.5-2.5-2.5-2.5-2.4-2.4-2.4-2.42.4-2.4-2.5-2.0-2.02.1
Body weight2.912.518.1-4.04.2-4.3-3.73.8-3.8-3.7-3.7-3.7-3.7-3.7-3.8-3.6-3.4-3.23.2-3.2-3.4-2.4-2.42.3
Weight adjusted by age0.40.61.6-0.91.2-1.2-1.30.8-0.8-0.8-0.9-0.9-0.9-0.7-1.0-0.8-0.6-0.50.5-0.5-0.7-0.2-0.10.1
Bone surface4.98.911.0-2.52.1-2.0-1.83.2-3.2-3.2-3.1-3.1-3.1-3.3-2.9-3.2-3.3-3.33.3-3.3-3.1-3.2-3.12.8
Bone volume2.34.16.1-1.30.9-0.8-0.72.1-2.1-2.1-2.0-2.0-2.0-2.2-1.8-2.1-2.3-2.42.4-2.4-2.1-2.5-2.52.2
Breakpoint value in progressive ratio session1.82.22.9-1.61.7-1.7-1.71.6-1.6-1.6-1.6-1.6-1.6-1.5-1.6-1.5-1.4-1.31.3-1.3-1.6-1.0-0.80.9
Number of licking bursts0.10.10.20.2-0.40.50.20.3-0.3-0.3-0.1-0.1-0.1-0.3-0.2-0.2-0.3-0.30.4-0.4-0.1-0.4-0.40.1
Context. condit. distance diff. score0.50.61.71.1-1.21.31.3-0.80.80.80.80.80.80.70.80.70.50.5-0.40.40.50.10.1-0.0
Locomotion velocity, session 10.00.00.00.0-0.00.00.10.0-0.0-0.1-0.0-0.0-0.0-0.1-0.10.0-0.1-0.10.1-0.1-0.1-0.1-0.10.2
Locomotion distance, session 11.72.13.1-0.90.8-0.8-0.51.4-1.5-1.5-1.4-1.4-1.4-1.5-1.4-1.5-1.6-1.71.7-1.7-1.6-1.7-1.71.7
Locomotion velocity, session 21.61.83.2-1.81.8-1.8-1.71.5-1.5-1.4-1.4-1.4-1.4-1.3-1.5-1.3-1.1-1.11.0-1.0-1.2-0.6-0.60.6
Locomotion distance, session 21.31.92.1-1.31.3-1.3-1.11.5-1.5-1.5-1.4-1.4-1.4-1.5-1.4-1.4-1.4-1.41.4-1.4-1.5-1.3-1.21.2
Locomotion velocity, session 31.01.12.6-0.40.3-0.30.10.9-0.9-1.0-0.9-0.9-0.9-1.1-0.8-1.0-1.2-1.31.3-1.3-1.2-1.5-1.51.6
Locomotion distance, session 30.10.10.5-0.10.0-0.00.20.2-0.2-0.3-0.2-0.2-0.2-0.3-0.3-0.2-0.3-0.40.4-0.4-0.5-0.4-0.40.7
Stereotopy head waving bouts, day 30.40.51.50.1-0.10.10.40.4-0.4-0.4-0.5-0.5-0.5-0.5-0.3-0.6-0.8-0.80.9-0.9-0.7-1.2-1.21.2
Stereotopy head waving duration, day 30.20.20.90.8-0.70.80.9-0.40.30.30.20.20.20.20.50.1-0.0-0.10.2-0.20.1-0.5-0.60.4
Locomotion velocity, session 70.60.71.8-0.30.3-0.30.00.7-0.7-0.8-0.7-0.8-0.8-0.8-0.6-0.8-1.0-1.01.0-1.0-1.0-1.2-1.21.3
Locomotion distance, session 70.40.50.8-0.70.6-0.6-0.50.8-0.8-0.8-0.7-0.7-0.7-0.8-0.8-0.7-0.8-0.80.8-0.8-0.9-0.7-0.70.8
Stereotopy head waving bouts, day 70.50.51.7-0.1-0.10.10.40.5-0.5-0.5-0.5-0.6-0.6-0.6-0.2-0.7-0.8-0.91.0-1.0-0.7-1.3-1.31.1
Stereotopy head waving duration, day 71.72.03.0-1.20.9-0.9-0.61.4-1.4-1.4-1.5-1.5-1.5-1.5-1.1-1.6-1.6-1.61.6-1.6-1.4-1.7-1.71.4
Locomotion velocity, session 81.01.21.9-1.41.2-1.1-1.31.3-1.3-1.3-1.2-1.2-1.2-1.2-1.3-1.2-1.0-1.01.0-1.0-1.0-0.7-0.60.5
Locomotion distance, session 80.10.10.60.5-0.70.80.8-0.10.10.10.20.20.2-0.00.10.1-0.1-0.20.2-0.2-0.1-0.5-0.40.5
Degree of sensitization distance0.60.70.8-0.60.6-0.6-0.60.9-0.9-0.9-0.9-0.9-0.9-0.9-0.7-0.9-0.9-0.90.9-0.9-0.9-0.8-0.80.8
Degree of sensitization stereotypy0.70.71.2-0.70.5-0.4-0.30.8-0.8-0.9-0.9-0.9-0.9-0.9-0.6-0.9-1.0-1.01.0-1.0-0.8-1.1-1.10.8
Conditioned locomotion0.50.62.7-1.21.1-1.2-1.60.5-0.5-0.4-0.4-0.4-0.4-0.3-0.6-0.20.10.2-0.30.30.10.90.9-1.1
Cocaine response after cond. corrected0.00.00.10.2-0.20.20.4-0.20.20.20.20.20.20.10.20.10.10.0-0.00.00.0-0.1-0.10.1
Cocaine response after cond. not corrected0.10.10.20.2-0.20.20.40.1-0.1-0.1-0.1-0.1-0.1-0.10.0-0.1-0.3-0.30.3-0.3-0.2-0.5-0.50.4
Cocaine response before conditioning0.10.10.2-0.10.00.0-0.10.4-0.4-0.4-0.4-0.4-0.4-0.4-0.2-0.4-0.4-0.40.4-0.4-0.2-0.5-0.50.2
Saline control response2.23.04.7-2.12.0-2.0-2.21.9-1.9-1.9-1.9-1.9-1.9-1.8-1.8-1.8-1.6-1.51.5-1.5-1.3-1.0-1.00.5
Bone: connectivity density5.38.310.5-2.31.7-1.6-1.63.0-3.1-3.1-3.0-3.0-3.0-3.1-2.8-3.1-3.2-3.23.2-3.2-3.0-3.1-3.12.8
Bone: cortical apparent density0.10.10.4-0.40.5-0.5-0.60.2-0.1-0.1-0.1-0.1-0.1-0.1-0.30.00.10.2-0.20.2-0.00.40.5-0.3
Bone: cortical area0.10.20.7-0.60.5-0.5-0.90.3-0.3-0.3-0.2-0.2-0.2-0.2-0.3-0.10.00.1-0.10.10.20.40.5-0.8
Bone: cortical porosity0.10.10.2-0.20.4-0.4-0.20.3-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.3-0.3-0.30.3-0.3-0.2-0.3-0.30.1
Bone: cortical porosity0.20.30.6-0.60.7-0.7-0.60.5-0.5-0.5-0.6-0.6-0.6-0.5-0.5-0.5-0.5-0.40.4-0.4-0.3-0.3-0.30.1
Bone: cortical thickness1.01.77.4-2.22.1-2.1-2.71.2-1.2-1.1-1.0-1.0-1.0-0.9-1.3-0.8-0.3-0.10.0-0.0-0.20.91.0-1.3
Bone: cortical thickness0.60.72.5-1.41.0-1.0-1.60.9-0.9-0.9-0.9-0.9-0.9-0.8-0.9-0.7-0.5-0.40.3-0.3-0.40.10.2-0.4
Bone: cortical tissue density0.10.10.6-0.60.7-0.7-0.80.3-0.3-0.3-0.2-0.2-0.2-0.2-0.4-0.10.00.1-0.10.1-0.20.40.5-0.3
Condit. Reinf. active minus inactive responses0.40.40.9-0.40.4-0.4-0.10.6-0.7-0.7-0.6-0.6-0.6-0.7-0.6-0.6-0.8-0.80.8-0.8-0.8-0.8-0.81.0
Condit. Reinf. active-inactive response ratio0.10.10.5-0.00.1-0.10.10.2-0.2-0.2-0.3-0.3-0.3-0.3-0.2-0.3-0.4-0.40.4-0.4-0.5-0.5-0.50.7
Condit. Reinf. active responses0.00.00.2-0.00.1-0.10.10.1-0.1-0.2-0.1-0.1-0.1-0.2-0.2-0.1-0.2-0.20.2-0.2-0.3-0.2-0.20.4
Condit. Reinf. inactive responses0.10.20.20.4-0.40.30.3-0.40.40.40.40.40.40.40.40.40.40.4-0.40.40.40.40.4-0.3
Incentive salience index mean0.30.40.7-0.40.3-0.3-0.10.6-0.6-0.7-0.6-0.6-0.6-0.7-0.6-0.5-0.7-0.70.7-0.7-0.8-0.7-0.70.8
Condit. Reinf. lever presses0.00.00.10.0-0.20.20.20.1-0.1-0.10.10.10.1-0.0-0.10.2-0.00.0-0.00.00.00.10.1-0.1
Condit. Reinf. active minus inactive responses0.30.31.30.5-0.50.50.90.1-0.1-0.2-0.1-0.1-0.1-0.3-0.0-0.3-0.6-0.60.7-0.7-0.6-1.0-1.01.1
Condit. Reinf. active-inactive response ratio0.50.62.51.3-1.31.31.6-0.80.80.70.80.80.80.60.80.60.30.2-0.20.20.3-0.3-0.30.4
Condit. Reinf. active responses0.81.12.6-0.30.3-0.20.20.8-0.9-0.9-0.9-0.9-0.9-1.0-0.7-1.0-1.2-1.31.3-1.3-1.2-1.5-1.61.6
Condit. Reinf. inactive responses1.72.22.6-1.41.3-1.3-1.11.5-1.5-1.6-1.6-1.6-1.6-1.6-1.4-1.6-1.6-1.61.6-1.6-1.5-1.5-1.51.4
Condit. Reinf. lever presses1.41.92.6-1.00.8-0.8-0.71.5-1.5-1.5-1.4-1.4-1.4-1.5-1.3-1.5-1.6-1.61.6-1.6-1.4-1.6-1.61.3
Condit. Reinf. lever reinforcers received1.11.52.9-0.50.5-0.5-0.11.1-1.1-1.2-1.1-1.1-1.1-1.3-1.0-1.2-1.4-1.51.5-1.5-1.4-1.7-1.71.7
Conditioned reinforcement - actives0.61.01.50.8-0.60.40.4-1.01.11.11.01.01.01.10.91.11.21.2-1.21.21.01.21.1-1.1
Conditioned reinforcement - inactives1.62.45.22.3-2.32.22.1-1.71.71.61.61.61.61.51.71.51.21.1-1.11.11.00.60.6-0.3
Conditioned locomotion8.310.817.04.1-3.93.93.6-3.63.53.53.53.53.53.43.53.43.13.0-2.92.92.92.22.2-1.8
Patch foraging indifference point 0 sec0.10.20.60.4-0.10.00.6-0.50.50.50.40.40.40.40.80.40.30.3-0.30.30.50.10.1-0.3
Patch foraging indifference point AUC0.10.20.7-0.50.8-0.8-0.90.4-0.4-0.4-0.2-0.2-0.2-0.3-0.6-0.1-0.10.0-0.10.1-0.20.50.5-0.4
Delay disc. indifference point, 0s delay1.01.12.7-0.30.8-0.80.10.8-0.9-0.9-0.9-0.9-0.9-1.0-0.6-1.0-1.2-1.31.3-1.3-0.9-1.5-1.61.2
Delay disc. indifference point, 16s delay0.50.61.51.2-0.80.91.1-0.90.80.80.80.80.80.70.90.70.60.5-0.50.50.70.20.1-0.2
Delay disc. indifference point, 2s delay0.20.20.70.8-0.70.80.7-0.10.10.10.10.10.1-0.00.1-0.0-0.2-0.30.3-0.3-0.1-0.6-0.60.5
Delay disc. indifference point, 24s delay0.10.10.4-0.60.4-0.5-0.3-0.10.10.10.10.10.10.20.10.10.30.3-0.30.30.40.40.5-0.5
Delay disc. indifference point, 4s delay0.40.40.8-0.00.6-0.5-0.10.6-0.6-0.6-0.5-0.5-0.5-0.7-0.7-0.6-0.7-0.80.8-0.8-0.8-0.7-0.90.9
Delay disc. indifference point, 8s delay0.30.40.6-0.70.8-0.8-0.30.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.7-0.70.7-0.7-0.5-0.7-0.80.7
Indifference point function ln k2.54.36.82.5-2.62.52.4-2.32.32.32.22.22.22.22.32.11.91.8-1.81.81.91.21.0-1.0
Indifference point function log k2.54.36.82.5-2.62.52.4-2.32.32.32.22.22.22.22.32.11.91.8-1.81.81.91.21.0-1.0
Patch foraging total patch changes 0 sec0.10.20.50.20.1-0.20.2-0.50.50.50.50.50.50.50.70.40.50.5-0.50.50.60.40.5-0.7
Patch foraging total patch changes 12 sec1.51.94.0-1.72.0-2.0-1.71.6-1.6-1.5-1.4-1.4-1.4-1.5-1.5-1.3-1.2-1.11.1-1.1-1.2-0.6-0.60.4
Patch foraging total patch changes 18 sec0.20.30.6-0.40.7-0.7-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.60.5-0.5-0.5-0.4-0.40.3
Patch foraging total patch changes 24 sec0.20.30.9-0.80.9-1.0-0.90.5-0.5-0.5-0.4-0.4-0.4-0.4-0.6-0.3-0.2-0.20.1-0.1-0.30.30.2-0.1
Patch foraging total patch changes 6 sec1.21.83.5-1.31.8-1.9-1.11.4-1.4-1.4-1.4-1.4-1.4-1.4-1.2-1.4-1.4-1.31.3-1.3-1.2-1.1-1.20.9
Patch foraging time to switch 0 sec2.55.06.4-1.61.4-1.2-1.42.3-2.3-2.3-2.4-2.4-2.4-2.4-2.2-2.5-2.5-2.52.5-2.5-2.3-2.5-2.52.3
Patch foraging water rate 0 sec5.311.113.12.9-2.82.72.5-3.53.53.53.63.63.63.53.43.63.53.5-3.53.53.43.33.2-3.1
Patch foraging water rate 12 sec6.914.417.23.5-3.33.23.2-4.04.04.14.14.14.14.13.74.14.04.0-3.93.93.83.53.5-3.1
Patch foraging water rate 18 sec1.62.52.91.5-1.71.71.5-1.71.71.71.71.71.71.71.51.61.61.6-1.61.61.61.21.3-1.2
Patch foraging water rate 24 sec4.15.87.01.9-1.61.51.7-2.52.52.52.62.62.62.62.42.62.62.6-2.62.62.52.52.5-2.3
Patch foraging water rate 6 sec3.45.06.11.8-2.12.11.4-2.32.32.32.32.32.32.42.02.32.42.5-2.52.52.32.32.3-2.2
Seeking ratio, delayed vs. immediate footshock0.60.71.3-0.50.7-0.8-0.20.7-0.7-0.7-0.8-0.8-0.8-0.8-0.7-0.9-0.9-0.91.0-1.0-0.8-1.1-1.11.1
Distance traveled before self-admin0.30.40.7-0.40.10.0-0.10.6-0.6-0.6-0.6-0.6-0.6-0.6-0.5-0.6-0.7-0.70.8-0.8-0.7-0.8-0.80.9
Distance traveled after self-admin0.00.00.1-0.2-0.20.3-0.10.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.2-0.2-0.1-0.3-0.20.2
Extensor digitorum longus weight3.915.333.1-5.25.5-5.5-5.84.3-4.2-4.1-4.2-4.2-4.2-3.8-4.5-3.8-3.1-2.82.6-2.6-3.2-1.2-1.00.9
Bone: elastic displacement1.72.04.20.4-0.20.20.1-1.21.21.31.31.31.31.41.11.51.71.7-1.81.81.52.02.0-1.9
Bone: elastic work0.50.62.6-1.41.5-1.5-1.60.7-0.7-0.6-0.6-0.6-0.6-0.5-0.8-0.4-0.1-0.0-0.10.1-0.10.60.7-0.7
Bone: endosteal estimation0.30.73.41.5-1.41.41.8-0.70.60.60.60.60.60.40.80.40.0-0.10.2-0.20.1-0.7-0.80.8
Bone: endosteal perimeter0.71.57.22.1-2.02.02.7-1.01.00.90.90.90.90.61.20.60.1-0.10.2-0.20.1-1.0-1.21.3
Epididymis fat weight3.311.419.64.4-4.24.24.0-3.73.73.73.53.53.53.53.73.43.02.9-2.82.83.11.91.6-1.8
Delta time in closed arm before/after self-admin0.50.51.7-1.01.3-1.3-1.10.8-0.7-0.7-0.7-0.7-0.6-0.6-0.8-0.6-0.4-0.40.3-0.3-0.50.00.1-0.1
Delta time in open arm before/after self-admin0.10.10.4-0.4-0.10.10.10.3-0.3-0.3-0.3-0.3-0.3-0.3-0.1-0.4-0.4-0.50.5-0.5-0.4-0.6-0.60.6
Diff in mean of infusions in LGA sessions0.30.30.9-0.80.6-0.6-1.00.7-0.7-0.7-0.7-0.7-0.6-0.6-0.6-0.6-0.4-0.40.4-0.4-0.5-0.1-0.10.1
Delay discount exponential model param0.40.51.00.2-0.40.40.1-0.60.60.60.60.60.60.70.60.60.80.8-0.80.80.70.91.0-0.9
Extinction: sum of active levers before priming2.73.04.0-2.01.4-1.4-1.51.9-1.9-1.9-1.9-1.9-1.9-1.9-1.8-1.8-1.8-1.81.8-1.8-1.7-1.5-1.51.4
Active lever presses in extinction session 60.50.51.5-0.91.2-1.2-1.10.7-0.7-0.6-0.6-0.6-0.6-0.6-1.0-0.6-0.3-0.30.2-0.2-0.8-0.10.30.3
Bone: final force1.21.92.5-1.51.3-1.3-1.51.6-1.6-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.4-1.31.3-1.3-1.2-1.0-1.00.7
Bone: final moment1.11.82.3-1.51.3-1.3-1.51.5-1.5-1.5-1.5-1.5-1.5-1.4-1.5-1.4-1.3-1.31.2-1.2-1.2-0.9-0.90.7
Food consumed during 24 hour testing period0.60.81.20.9-1.11.10.7-0.80.80.80.90.90.90.80.80.90.90.8-0.80.81.00.80.7-1.0
Glucose0.50.83.11.3-1.61.61.8-0.40.40.30.30.30.30.10.40.0-0.3-0.50.6-0.6-0.3-1.2-1.21.4
Heart weight0.50.72.30.2-0.10.20.40.5-0.5-0.6-0.7-0.7-0.7-0.7-0.3-0.8-1.0-1.11.1-1.1-0.8-1.4-1.51.3
Delay discount hyperbolic model param0.40.41.00.1-0.30.3-0.0-0.50.60.60.50.50.50.60.60.60.80.8-0.80.80.80.81.0-1.0
Intermittent access intake day 1-15 change2.04.26.72.6-2.52.52.2-2.22.22.22.12.12.12.12.12.11.91.8-1.81.82.01.31.2-1.3
Intermittent access intake escalation1.93.95.92.4-2.42.42.0-2.12.12.12.02.02.02.02.02.01.91.8-1.71.72.01.31.3-1.4
Intermittent access intake escalation 22.32.64.72.2-1.81.81.8-1.81.81.81.71.71.71.71.71.61.51.4-1.41.41.61.00.9-1.1
Intermitt. access day 1 inactive lever presses0.00.00.2-0.40.3-0.50.0-0.10.10.10.10.10.10.10.20.10.10.1-0.10.10.20.10.2-0.0
Intermitt. access day 15 inactive lever presses0.30.52.11.4-1.21.11.3-0.80.80.80.60.60.60.60.70.50.30.2-0.20.20.5-0.2-0.40.2
Intermitt. access escalation Index3.04.36.02.5-2.22.22.0-2.22.22.22.22.22.22.12.12.22.02.0-2.02.02.01.61.6-1.6
Intermittent access day 1 total infusions0.40.62.41.2-0.60.61.2-0.10.10.0-0.1-0.1-0.1-0.20.2-0.3-0.6-0.70.8-0.8-0.7-1.3-1.41.5
Intermittent access day 15 total infusions2.53.89.53.1-2.72.62.8-2.22.22.12.02.02.01.92.21.81.51.3-1.31.31.50.60.4-0.3
Intermittent access terminal intake (last 3 days)1.52.07.42.7-1.91.92.4-1.61.61.51.41.41.41.31.61.20.90.7-0.60.60.8-0.0-0.20.3
Intermittent access total infusions0.70.84.02.0-1.11.11.7-1.00.90.90.80.80.80.71.00.60.30.2-0.10.10.2-0.4-0.50.7
Intermittent access day 1 locomotion0.20.21.10.9-0.40.30.9-0.20.20.20.10.10.10.00.4-0.1-0.2-0.30.4-0.4-0.5-0.7-0.71.1
Intermittent access day 15 total locomotion1.93.410.53.2-2.82.82.7-2.02.02.01.81.81.81.81.91.71.31.2-1.11.11.20.40.3-0.2
Intermittent access total locomotion3.13.712.93.6-2.82.83.1-2.12.02.01.91.91.91.82.11.71.21.0-1.01.01.10.10.00.2
Intermittent access standard deviation0.30.51.61.3-0.80.81.0-0.90.90.80.70.70.70.80.80.70.60.5-0.50.50.60.20.2-0.2
Left kidney weight0.62.85.22.2-1.91.92.3-1.91.91.91.81.81.81.82.01.71.51.4-1.31.31.60.80.7-0.7
Right kidney weight0.73.34.02.0-2.02.01.9-2.02.01.91.91.91.91.92.01.91.71.7-1.71.72.01.31.2-1.5
Cocaine induced anxiety0.10.10.80.0-0.80.90.30.1-0.1-0.1-0.0-0.0-0.0-0.2-0.1-0.1-0.2-0.20.3-0.3-0.1-0.3-0.30.3
Post-drug Anxiety0.40.51.0-1.00.3-0.2-0.70.8-0.8-0.8-0.8-0.8-0.8-0.8-0.7-0.8-0.7-0.70.7-0.7-0.5-0.6-0.60.4
Baseline Anxiety0.30.41.5-1.01.2-1.2-1.00.6-0.5-0.5-0.6-0.6-0.6-0.5-0.6-0.5-0.4-0.30.3-0.3-0.3-0.1-0.1-0.0
Tail length0.20.73.3-1.51.2-1.2-1.80.7-0.7-0.7-0.6-0.6-0.6-0.5-0.7-0.5-0.10.0-0.10.1-0.10.70.7-0.9
Length with tail0.94.011.6-3.13.0-3.0-3.42.2-2.1-2.1-2.1-2.1-2.1-1.8-2.3-1.9-1.3-1.11.0-1.0-1.2-0.2-0.0-0.3
Length without tail1.13.69.3-2.73.0-3.1-2.92.0-2.0-1.9-2.0-2.0-2.0-1.7-2.1-1.8-1.3-1.21.1-1.1-1.2-0.4-0.30.0
Times rat made contact with spout1.01.21.5-0.90.7-0.7-0.61.2-1.2-1.2-1.1-1.1-1.1-1.2-1.1-1.1-1.2-1.21.2-1.2-1.0-1.2-1.20.9
Lifetime Intake0.30.42.01.4-0.50.41.2-0.70.70.70.50.50.50.50.70.40.20.1-0.10.10.0-0.3-0.40.7
Liver weight, left0.81.31.80.9-0.90.80.7-1.21.21.21.21.21.21.21.11.21.31.3-1.31.31.31.21.2-1.2
Liver weight, right1.32.42.71.5-1.51.51.4-1.71.71.71.71.71.71.61.61.61.61.5-1.51.51.61.31.2-1.2
Locomotor activity1.11.72.11.2-1.51.41.2-1.31.31.31.41.41.41.31.31.41.31.3-1.31.31.31.11.0-1.1
Locomotor testing distance1.12.12.61.3-1.31.21.3-1.51.51.51.61.61.61.51.51.61.51.5-1.51.51.51.31.1-1.2
Locomotor testing rearing0.30.51.81.1-1.31.31.3-0.70.70.70.70.70.70.60.70.60.40.3-0.30.30.3-0.0-0.00.3
Locomotion in novel chamber3.44.39.02.9-3.03.02.9-2.32.32.22.12.12.12.12.42.01.71.5-1.41.41.70.70.6-0.6
Locomotion in novel chamber post-restriction2.03.36.42.5-2.32.32.5-2.02.01.91.91.91.91.82.11.81.51.4-1.31.31.50.80.7-0.8
Fecal boli incidents, locomotor time 10.10.10.20.40.1-0.10.3-0.30.30.30.40.40.40.30.30.40.30.2-0.30.30.10.30.2-0.2
Change in fecal boli incidents, locomotor task0.20.20.4-0.60.4-0.4-0.30.4-0.4-0.4-0.4-0.4-0.4-0.4-0.5-0.4-0.4-0.40.4-0.4-0.4-0.4-0.40.5
Time >=10cm from walls, locomotor time 10.40.51.91.3-0.90.91.4-0.30.30.20.30.30.30.00.30.1-0.3-0.40.5-0.5-0.5-0.8-1.11.2
Bouts of movement, locomotor time 10.20.20.7-0.70.8-0.8-0.80.3-0.3-0.2-0.1-0.1-0.1-0.1-0.30.00.10.2-0.20.20.10.60.5-0.7
Total resting periods, locomotor time 10.10.10.6-0.30.4-0.4-0.4-0.10.10.10.20.20.20.20.00.30.40.4-0.40.40.40.70.6-0.8
Rest time, locomotor task time 12.43.03.61.8-1.51.41.5-1.91.91.91.91.91.91.91.81.91.81.8-1.71.71.81.61.4-1.5
Distance moved, locomotor task time 10.71.11.8-0.40.3-0.2-0.31.0-1.0-1.0-1.0-1.0-1.0-1.1-1.0-1.1-1.2-1.21.2-1.2-1.2-1.3-1.31.3
Vertical activity count, locomotor time 10.10.31.40.7-1.21.20.9-0.30.30.30.30.30.20.20.40.20.0-0.10.1-0.10.2-0.4-0.50.3
Time >=10cm from walls, locomotor time 20.30.40.80.9-0.40.30.4-0.70.70.70.80.80.80.70.50.80.70.7-0.70.70.50.80.6-0.4
Bouts of movement, locomotor time 20.20.41.9-1.11.3-1.4-0.70.6-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.4-0.4-0.40.3-0.3-0.4-0.1-0.10.1
Total resting periods, locomotor time 20.10.21.1-0.81.0-1.1-0.40.4-0.4-0.4-0.3-0.3-0.3-0.4-0.3-0.3-0.3-0.30.3-0.3-0.3-0.2-0.20.2
Rest time, locomotor task time 20.60.72.41.5-1.21.31.6-0.90.90.90.80.80.80.81.10.70.50.4-0.30.30.6-0.1-0.20.1
Distance moved, locomotor task time 20.20.21.1-0.80.6-0.6-1.10.4-0.4-0.3-0.3-0.3-0.3-0.2-0.6-0.20.00.1-0.10.1-0.10.50.5-0.4
Vertical activity count, locomotor time 20.71.02.5-0.2-0.20.1-0.3-0.70.80.80.80.80.80.90.60.91.21.3-1.31.31.21.61.6-1.6
Light reinforcement 10.61.42.11.4-1.41.41.0-1.31.21.21.21.21.21.21.11.21.21.1-1.11.11.11.01.0-0.9
Light reinforcement 22.13.24.12.0-1.81.81.6-2.02.02.01.81.81.82.01.91.81.81.8-1.71.71.71.31.3-1.2
Bone: marrow area0.30.73.61.5-1.41.41.9-0.70.70.60.60.60.60.40.80.40.0-0.10.2-0.20.1-0.7-0.90.8
Bone: maximum diameter0.20.30.50.6-0.70.70.5-0.50.50.50.60.60.60.50.60.60.50.5-0.50.50.70.40.4-0.7
Bone: maximum force2.95.16.0-1.91.9-1.9-1.52.4-2.4-2.4-2.3-2.3-2.3-2.4-2.3-2.4-2.4-2.42.4-2.4-2.3-2.3-2.32.1
Bone: maximum moment2.64.65.3-1.81.9-1.8-1.42.2-2.2-2.3-2.2-2.2-2.2-2.3-2.2-2.2-2.3-2.32.3-2.3-2.2-2.1-2.12.0
Mean time between licks in bursts0.20.50.8-0.90.9-0.9-0.90.7-0.7-0.7-0.7-0.7-0.7-0.7-0.8-0.7-0.6-0.50.5-0.5-0.6-0.3-0.20.2
Mean num. licks in bursts0.10.20.4-0.50.6-0.7-0.30.3-0.3-0.3-0.4-0.4-0.4-0.3-0.3-0.4-0.3-0.30.3-0.3-0.4-0.4-0.40.6
Cd content in liver1.31.42.81.7-1.61.61.7-1.31.31.31.31.31.31.21.21.21.00.9-0.90.90.90.50.4-0.3
Co content in liver1.82.13.41.0-0.70.70.5-1.41.41.51.41.41.41.51.31.51.71.7-1.71.71.41.91.8-1.5
Cu content in liver0.00.00.10.20.1-0.10.1-0.30.30.30.20.20.20.30.20.20.30.2-0.30.30.00.30.20.1
Fe content in liver0.10.10.4-0.60.6-0.7-0.50.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.20.2-0.2-0.3-0.0-0.00.2
K content in liver0.90.81.0-0.90.9-0.8-0.70.9-0.9-0.9-1.0-1.0-1.0-0.9-0.9-1.0-1.0-0.90.9-0.9-1.0-0.9-0.90.9
Mg content in liver0.10.10.40.5-0.40.40.6-0.20.20.20.10.10.10.10.20.1-0.0-0.10.1-0.1-0.0-0.3-0.40.4
Mn content in liver1.61.72.7-1.61.6-1.6-1.61.5-1.5-1.4-1.4-1.4-1.4-1.4-1.5-1.3-1.2-1.11.1-1.1-1.3-0.7-0.70.8
Na content in liver0.50.51.00.4-0.40.40.1-0.60.60.60.70.70.70.70.50.70.80.8-0.90.90.81.01.0-1.0
Rb content in liver0.30.31.41.0-0.80.81.2-0.40.40.30.30.30.30.20.40.2-0.0-0.10.2-0.2-0.0-0.5-0.70.6
Se content in liver0.10.10.50.3-0.10.20.40.0-0.0-0.0-0.1-0.1-0.1-0.1-0.0-0.1-0.3-0.30.3-0.3-0.3-0.5-0.60.7
Sr content in liver0.50.52.1-1.11.2-1.2-1.40.6-0.6-0.5-0.6-0.6-0.6-0.4-0.7-0.4-0.1-0.10.0-0.0-0.20.40.5-0.5
Zn content in liver0.10.10.5-0.50.6-0.6-0.70.2-0.2-0.1-0.2-0.2-0.2-0.1-0.3-0.10.10.1-0.20.2-0.00.40.4-0.3
Bone: minimum diameter0.30.62.20.8-0.80.91.5-0.0-0.0-0.10.00.00.0-0.30.2-0.2-0.6-0.70.8-0.8-0.5-1.3-1.41.3
Time in familiar zone, hab. session 10.20.20.80.7-0.70.70.9-0.30.30.30.40.40.40.20.30.30.10.00.0-0.0-0.1-0.2-0.30.6
Time in novel zone, hab. session 10.00.00.3-0.20.2-0.2-0.30.0-0.0-0.0-0.1-0.1-0.10.00.1-0.00.10.1-0.10.10.30.20.2-0.5
Total zone transitions, hab. session 10.40.60.8-0.70.6-0.6-0.80.9-0.9-0.9-0.9-0.9-0.9-0.9-0.8-0.9-0.8-0.80.8-0.8-0.7-0.7-0.60.4
Total locomotion distance, hab. session 10.20.30.80.9-0.90.90.9-0.50.50.50.50.50.50.40.60.40.30.3-0.20.20.40.0-0.0-0.0
Locomotion velocity, hab. session 10.00.10.20.5-0.50.50.4-0.20.20.20.30.30.20.20.20.20.10.1-0.10.10.20.00.0-0.0
Time in familiar zone, hab. session 20.10.10.3-0.40.2-0.1-0.50.2-0.2-0.2-0.0-0.0-0.0-0.1-0.30.10.10.2-0.20.20.10.40.5-0.5
Time in novel zone, hab. session 20.50.51.1-0.20.3-0.40.00.5-0.5-0.5-0.6-0.6-0.7-0.6-0.4-0.7-0.8-0.80.8-0.8-0.7-1.0-1.11.0
Total zone transitions, hab. session 24.45.67.6-1.71.7-1.6-1.12.3-2.4-2.4-2.4-2.4-2.4-2.5-2.1-2.5-2.6-2.72.7-2.7-2.5-2.8-2.72.6
Total locomotion distance, hab. session 20.71.02.1-0.30.3-0.20.10.8-0.8-0.9-0.9-0.9-0.9-1.0-0.7-1.0-1.2-1.21.2-1.2-1.1-1.4-1.41.4
Locomotion velocity, hab. session 20.40.61.70.1-0.00.00.40.5-0.5-0.6-0.6-0.6-0.6-0.7-0.4-0.7-0.9-0.91.0-1.0-0.9-1.3-1.31.3
Novel to familiar place preference ratio0.40.50.7-0.50.5-0.5-0.40.7-0.7-0.7-0.8-0.8-0.8-0.7-0.6-0.8-0.8-0.80.8-0.8-0.6-0.9-0.80.6
Novelty place preference0.20.30.6-0.20.2-0.2-0.10.4-0.4-0.4-0.5-0.5-0.5-0.5-0.3-0.6-0.6-0.60.6-0.6-0.4-0.8-0.80.5
Time in novel zone, NPP test0.30.30.7-0.20.3-0.3-0.20.5-0.5-0.5-0.6-0.6-0.6-0.5-0.4-0.7-0.6-0.70.7-0.7-0.4-0.8-0.80.6
Total zone transitions, NPP test1.72.43.0-1.31.1-1.0-0.91.7-1.7-1.7-1.6-1.6-1.6-1.7-1.6-1.6-1.7-1.71.7-1.7-1.7-1.6-1.61.5
Total locomotion distance, NPP test0.20.20.80.1-0.10.10.30.3-0.3-0.3-0.3-0.3-0.3-0.4-0.4-0.3-0.5-0.50.6-0.6-0.7-0.7-0.70.9
Locomotion velocity, NPP test0.10.10.50.2-0.10.20.30.2-0.2-0.2-0.1-0.1-0.1-0.3-0.3-0.2-0.3-0.40.4-0.4-0.5-0.5-0.50.7
Intraocular pressure1.31.92.61.0-0.70.70.8-1.41.41.41.51.51.51.41.41.51.51.5-1.61.61.61.61.5-1.6
Delta distance traveled before/after self-admin0.10.10.2-0.1-0.30.3-0.1-0.20.20.20.20.20.20.20.10.20.30.3-0.30.30.40.30.5-0.4
Delta ambulatory time before/after self-admin0.10.10.3-0.3-0.0-0.0-0.3-0.10.10.20.10.10.10.20.00.10.30.3-0.40.40.30.40.5-0.4
Parametrial fat weight1.43.28.82.8-2.93.02.7-1.91.91.81.81.81.81.72.01.61.21.1-1.01.01.30.20.2-0.2
Pavlov. Cond. lever latency0.30.30.50.5-0.40.30.4-0.70.70.70.60.60.60.70.70.60.60.6-0.60.60.70.50.5-0.5
Pavlov. Cond. magazine entry latency0.30.41.20.1-0.30.40.60.4-0.5-0.5-0.4-0.4-0.4-0.6-0.4-0.5-0.7-0.80.8-0.8-0.6-1.1-1.11.0
Pavlov. Cond. change in total contacts0.10.10.80.6-0.70.70.9-0.20.20.20.20.20.20.10.30.1-0.1-0.10.2-0.2-0.0-0.5-0.50.4
Pavlov. Cond. index score0.10.10.50.4-0.60.70.6-0.10.10.10.20.20.20.00.10.20.00.00.0-0.00.1-0.1-0.10.0
Pavlov. Cond. latency score0.10.10.20.2-0.40.50.40.1-0.1-0.2-0.0-0.0-0.0-0.2-0.2-0.1-0.2-0.30.3-0.3-0.2-0.4-0.40.3
Pavlov. Cond. lever contacts0.10.10.2-0.1-0.00.10.00.4-0.4-0.4-0.3-0.3-0.3-0.4-0.4-0.3-0.4-0.40.4-0.4-0.4-0.4-0.40.4
Pavlov. Cond. magazine entry number0.10.20.6-0.50.7-0.8-0.60.3-0.3-0.3-0.4-0.4-0.4-0.2-0.3-0.4-0.2-0.20.2-0.2-0.4-0.1-0.10.3
Pavlov. Cond. intertrial magazine entries0.60.71.20.5-0.40.30.2-0.90.90.90.90.90.90.90.70.91.01.0-1.01.00.91.11.1-0.9
Pavlov. Cond. lever-magazine prob. diff.0.00.10.40.3-0.50.60.5-0.00.00.00.20.20.2-0.00.00.1-0.1-0.10.1-0.10.0-0.2-0.20.1
Pavlov. Cond. response bias0.10.10.50.5-0.70.70.5-0.30.30.30.40.40.40.30.30.40.30.2-0.20.20.40.10.1-0.4
Pavlov. Cond. lever latency0.00.00.2-0.10.4-0.4-0.0-0.10.10.1-0.0-0.0-0.00.1-0.00.00.00.0-0.00.0-0.20.00.00.4
Pavlov. Cond. magazine entry latency4.65.66.7-2.32.0-1.9-1.92.6-2.6-2.6-2.5-2.5-2.5-2.6-2.4-2.5-2.5-2.52.5-2.5-2.3-2.2-2.21.8
Pavlov. Cond. change in total contacts0.50.91.5-0.50.2-0.2-0.31.0-1.0-1.0-0.9-0.9-0.9-1.0-0.7-1.0-1.1-1.11.2-1.2-0.9-1.2-1.20.8
Pavlov. Cond. index score1.11.52.0-1.00.7-0.6-0.81.4-1.4-1.4-1.3-1.3-1.3-1.4-1.2-1.4-1.4-1.41.4-1.4-1.1-1.3-1.30.8
Pavlov. Cond. latency score0.81.11.4-0.80.5-0.5-0.71.2-1.2-1.2-1.1-1.1-1.1-1.2-1.0-1.1-1.2-1.21.2-1.2-0.9-1.1-1.10.6
Pavlov. Cond. lever contacts0.00.00.1-0.0-0.30.4-0.00.2-0.2-0.2-0.1-0.1-0.1-0.2-0.1-0.2-0.2-0.20.2-0.20.1-0.2-0.2-0.2
Pavlov. Cond. magazine entry number5.36.67.92.5-2.32.22.1-2.82.82.82.72.72.72.82.62.82.72.7-2.62.62.52.32.3-2.0
Pavlov. Cond. intertrial magazine entries1.32.02.61.5-1.31.21.4-1.61.61.61.51.51.51.61.41.51.41.4-1.41.41.31.11.1-0.8
Pavlov. Cond. lever-magazine prob. diff.1.52.02.5-1.21.0-0.9-1.11.6-1.6-1.6-1.5-1.5-1.5-1.6-1.4-1.6-1.6-1.61.5-1.5-1.3-1.4-1.41.0
Pavlov. Cond. response bias1.21.62.1-1.10.8-0.7-0.81.4-1.4-1.4-1.3-1.3-1.3-1.4-1.2-1.4-1.4-1.41.4-1.4-1.1-1.3-1.30.9
Time in closed arm before self-admin0.20.20.90.9-0.60.60.9-0.50.50.40.30.30.30.30.50.20.10.0-0.00.0-0.1-0.4-0.30.6
Time in closed arm after self-admin0.10.10.30.6-0.0-0.00.2-0.30.30.30.30.30.30.30.30.30.30.3-0.30.30.20.30.4-0.2
Time in open arm before self-admin0.10.10.6-0.60.2-0.2-0.80.4-0.4-0.3-0.2-0.2-0.2-0.2-0.5-0.1-0.00.1-0.10.10.10.50.4-0.7
Time in open arm after self-admin0.60.61.2-1.10.5-0.4-0.80.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.8-0.8-0.80.8-0.8-0.7-0.6-0.60.4
Bone: periosteal estimation0.00.10.40.5-0.50.50.6-0.30.30.20.30.30.30.20.30.20.10.1-0.00.00.3-0.1-0.2-0.0
Bone: periosteal perimeter0.10.20.70.3-0.30.30.60.2-0.2-0.2-0.2-0.2-0.2-0.3-0.0-0.3-0.5-0.50.6-0.6-0.4-0.8-0.80.7
Bone: post-yield work3.75.413.6-0.40.5-0.40.61.8-1.8-1.9-1.9-1.9-1.9-2.2-1.6-2.2-2.7-2.92.9-2.9-2.6-3.5-3.63.7
Progressive ratio test 1 active lever presses0.10.10.10.20.2-0.40.1-0.30.30.30.30.30.30.30.30.30.30.3-0.30.30.00.40.30.0
Progressive ratio test 1 breakpoint0.10.10.20.20.3-0.40.1-0.20.20.30.30.30.30.20.20.30.30.3-0.30.30.00.40.30.0
Progressive ratio test 1 inactive lever presses0.00.00.2-0.00.3-0.50.0-0.10.10.20.10.10.10.10.10.10.10.1-0.10.1-0.20.20.20.3
Progressive ratio test 2 active lever presses0.80.92.41.5-1.00.91.4-1.11.11.11.01.01.01.01.10.90.80.7-0.70.70.60.30.20.1
Progressive ratio test 2 breakpoint0.80.92.31.5-1.00.91.3-1.21.11.11.01.01.01.01.11.00.80.7-0.70.70.60.40.3-0.0
Progressive ratio test 2 inactive lever presses3.04.812.83.6-2.72.63.0-2.52.52.52.32.32.32.32.52.11.81.6-1.61.61.60.90.6-0.4
Incentive Sensitization - Responses0.30.41.0-0.00.3-0.3-0.10.5-0.5-0.5-0.6-0.6-0.6-0.6-0.6-0.6-0.7-0.80.8-0.8-0.8-0.8-0.91.0
Incentive Sensitization - Breakpoint0.20.20.90.30.1-0.10.10.3-0.3-0.3-0.4-0.4-0.4-0.4-0.4-0.5-0.5-0.60.6-0.6-0.7-0.7-0.80.9
Sum of active levers in priming session hrs 5-62.32.14.40.5-0.80.80.1-1.21.21.31.41.41.41.41.01.51.71.7-1.81.81.62.12.1-2.0
Progressive ratio3.65.68.2-1.71.4-1.4-1.02.3-2.3-2.4-2.4-2.4-2.4-2.5-2.0-2.5-2.7-2.72.7-2.7-2.5-2.9-2.82.6
Food seeking constrained by brief footshock0.20.30.3-0.60.4-0.4-0.40.6-0.6-0.6-0.6-0.6-0.6-0.6-0.5-0.6-0.6-0.60.6-0.6-0.4-0.5-0.50.5
Seeking ratio, punishment vs. effort2.53.74.81.6-1.31.30.9-1.91.92.02.02.02.02.01.72.02.12.1-2.22.22.02.22.2-2.0
Retroperitoneal fat weight5.724.143.66.4-6.66.66.1-5.45.45.35.25.25.25.05.54.84.24.0-3.83.84.52.32.1-2.3
Reaction time number correct0.00.10.4-0.40.2-0.2-0.40.1-0.1-0.10.00.00.00.0-0.30.20.20.3-0.30.30.10.50.6-0.5
Reaction time mean minus median1.43.45.3-2.12.3-2.3-1.62.1-2.1-2.0-1.8-1.8-1.8-2.0-1.8-1.8-1.9-1.81.8-1.8-1.8-1.4-1.41.3
Reaction time mean minus median AUC0.71.93.8-1.81.9-1.9-1.41.6-1.6-1.5-1.3-1.3-1.3-1.5-1.4-1.2-1.3-1.21.2-1.2-1.3-0.6-0.70.7
Reaction time num false alarms0.30.51.80.0-0.20.2-0.2-0.40.50.50.60.60.60.60.50.70.70.8-0.80.80.81.11.1-1.3
Reaction time num false alarms AUC0.10.20.8-0.70.5-0.5-0.90.3-0.3-0.3-0.1-0.1-0.1-0.2-0.2-0.00.10.1-0.20.20.20.60.6-0.9
Reaction time trials correct on left0.00.10.4-0.40.2-0.2-0.40.1-0.1-0.10.00.00.00.0-0.30.20.20.3-0.30.30.10.50.6-0.5
Reaction time trials on left0.10.10.4-0.50.3-0.3-0.50.2-0.2-0.1-0.0-0.0-0.0-0.0-0.30.10.20.3-0.30.30.10.50.7-0.5
Reaction time mean0.20.30.60.0-0.10.1-0.00.5-0.5-0.5-0.4-0.4-0.4-0.6-0.4-0.5-0.7-0.70.7-0.7-0.5-0.7-0.80.6
Reaction time mean AUC0.20.30.70.1-0.10.10.10.4-0.5-0.5-0.4-0.4-0.4-0.5-0.3-0.5-0.6-0.70.7-0.7-0.5-0.7-0.80.7
Median of all reaction times0.10.20.60.6-0.70.70.40.1-0.2-0.2-0.2-0.2-0.2-0.3-0.1-0.3-0.4-0.50.5-0.5-0.2-0.7-0.80.6
Reaction time omissions1.62.43.9-2.01.9-1.9-1.81.8-1.8-1.7-1.6-1.6-1.6-1.7-1.7-1.5-1.4-1.41.3-1.3-1.4-0.8-0.70.7
Reaction time false alarm rate0.10.10.7-0.30.2-0.3-0.4-0.00.00.10.10.10.10.10.20.20.20.3-0.30.30.40.50.5-0.8
Reaction time premature initiation rate2.02.84.9-2.22.1-2.2-2.01.9-1.9-1.8-1.7-1.7-1.7-1.8-1.8-1.6-1.5-1.41.3-1.3-1.6-0.8-0.80.9
Reaction time premature initiations1.52.86.3-2.52.3-2.4-2.31.9-1.9-1.8-1.6-1.6-1.6-1.7-1.9-1.4-1.3-1.21.1-1.1-1.5-0.4-0.30.4
Std. dev. reaction times0.71.31.7-1.11.2-1.3-0.81.3-1.3-1.3-1.0-1.0-1.0-1.3-1.0-1.0-1.2-1.21.2-1.2-1.1-0.9-1.00.8
Reaction time trials completed0.10.10.4-0.50.3-0.3-0.50.2-0.2-0.1-0.0-0.0-0.0-0.0-0.30.10.20.3-0.30.30.10.50.7-0.5
Reaction time trials AUC0.00.10.3-0.40.2-0.2-0.40.1-0.1-0.1-0.0-0.0-0.0-0.0-0.30.10.20.2-0.30.30.10.50.6-0.4
Run reversals in cocaine runway, females1.81.82.4-0.90.9-0.9-0.91.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.41.4-1.4-1.5-1.3-1.31.5
Run reversals in cocaine runway, males0.30.30.8-0.30.3-0.3-0.3-0.30.30.40.30.30.30.40.30.40.60.6-0.70.70.70.80.9-0.9
Latency to leave start box in cocaine runway0.40.41.20.2-0.40.50.40.4-0.4-0.4-0.4-0.4-0.4-0.5-0.3-0.6-0.7-0.80.8-0.8-0.7-1.1-1.11.1
Latency to leave start box in cocaine runway, F0.40.51.10.2-0.10.30.20.5-0.5-0.5-0.6-0.6-0.6-0.6-0.5-0.6-0.8-0.80.9-0.9-0.8-1.1-1.11.0
Latency to leave start box in cocaine runway, M0.00.00.1-0.2-0.30.3-0.00.1-0.1-0.1-0.1-0.1-0.1-0.2-0.1-0.2-0.2-0.20.2-0.2-0.1-0.2-0.20.2
Std. dev. time between licks in bursts0.20.21.0-0.40.2-0.2-0.70.0-0.00.00.20.20.20.1-0.20.30.40.5-0.60.60.30.91.0-0.9
Total sessions with >9 infusions0.30.41.0-0.50.9-1.0-0.50.5-0.5-0.5-0.6-0.6-0.6-0.5-0.5-0.6-0.5-0.50.5-0.5-0.8-0.5-0.50.9
Short access day 1 total inactive lever presses1.11.42.81.7-1.51.41.5-1.31.31.31.31.31.31.21.31.21.01.0-0.90.91.00.60.5-0.5
Short access day 10 total inactive lever presses0.00.00.1-0.20.1-0.10.00.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.20.2-0.20.0-0.2-0.10.0
Short access day 1 total infusions0.20.30.90.9-0.30.10.8-0.80.80.80.60.60.60.70.80.50.50.4-0.40.40.40.2-0.10.2
Short access day 10 total infusions0.81.03.30.10.7-0.70.10.7-0.7-0.7-0.8-0.8-0.8-0.9-0.7-0.9-1.1-1.21.2-1.2-1.4-1.4-1.51.8
Short access total infusions0.30.41.3-0.00.7-0.9-0.10.4-0.4-0.4-0.5-0.5-0.5-0.5-0.4-0.6-0.6-0.70.7-0.7-0.8-0.8-0.91.1
Short access day 1 locomotion0.40.41.31.1-0.90.91.1-0.70.70.70.70.70.70.60.70.60.40.4-0.40.40.20.10.10.3
Short access day 10 total locomotion0.10.20.70.8-0.60.60.8-0.20.20.20.10.10.10.10.4-0.0-0.1-0.20.2-0.2-0.3-0.6-0.40.8
Short access total locomotion0.20.31.01.0-0.80.81.0-0.50.50.50.40.40.40.40.60.30.20.1-0.10.1-0.1-0.3-0.20.6
One hour access (0.3 mA shock)2.22.65.52.3-1.91.82.3-1.91.91.81.71.71.71.72.01.51.31.2-1.21.11.30.60.5-0.3
Compulsive drug intake1.11.36.1-2.52.0-2.1-1.91.1-1.1-1.0-1.0-1.0-1.0-0.9-1.0-0.8-0.5-0.40.3-0.3-0.50.20.3-0.3
One hour access (shock baseline)3.14.811.03.3-2.72.73.0-2.52.52.42.32.32.32.32.62.11.81.7-1.61.61.70.80.8-0.5
Social response proportion0.91.01.3-0.90.7-0.6-0.61.1-1.1-1.1-1.0-1.0-1.0-1.2-1.0-1.0-1.1-1.11.1-1.1-1.1-1.0-1.10.9
Social responses0.10.20.4-0.70.5-0.5-0.60.5-0.5-0.5-0.3-0.3-0.3-0.5-0.6-0.3-0.3-0.20.2-0.2-0.50.10.00.2
Social time0.50.72.0-1.11.4-1.4-1.00.9-0.8-0.8-0.8-0.8-0.8-0.8-0.9-0.8-0.7-0.70.6-0.6-0.8-0.4-0.50.6
Soleus weight4.713.816.64.1-3.93.83.6-4.04.04.04.04.04.03.93.93.93.73.6-3.53.53.62.92.8-2.6
Bone: stiffness2.33.74.8-1.41.4-1.4-1.01.9-2.0-2.0-2.0-2.0-2.0-2.0-1.8-2.1-2.1-2.22.2-2.2-1.9-2.2-2.21.9
Tibialis anterior weight3.010.034.2-4.85.4-5.4-5.83.2-3.2-3.0-3.1-3.1-3.1-2.6-3.6-2.6-1.6-1.31.1-1.1-1.80.50.8-0.8
Time to tail flick, vehicle, before self-admin1.51.62.7-0.50.5-0.4-0.51.2-1.2-1.2-1.3-1.3-1.3-1.3-1.1-1.3-1.4-1.51.5-1.5-1.3-1.6-1.61.5
Time to tail flick, vehicle, after self-admin2.83.74.3-1.81.9-1.9-1.41.9-1.9-2.0-2.0-2.0-2.0-2.0-1.8-2.0-2.0-2.02.0-2.0-2.1-1.9-1.82.0
Time to tail flick, test, before self-admin0.50.52.10.8-0.30.30.80.2-0.3-0.3-0.3-0.3-0.3-0.4-0.1-0.4-0.7-0.80.9-0.9-0.8-1.2-1.31.4
Time to tail flick, test, after self-admin0.00.00.30.50.00.00.2-0.20.20.20.20.20.20.2-0.00.20.20.2-0.20.20.20.20.3-0.3
Delta time to tail flick, vehicle, before/after SA1.01.02.0-1.11.4-1.4-0.91.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-0.9-0.90.9-0.9-1.1-0.7-0.60.9
Delta time to tail flick, test, before/after SA1.11.24.1-0.40.5-0.5-0.8-0.60.60.60.70.70.70.80.30.81.21.3-1.41.41.21.81.9-2.0
Tibia length0.20.62.60.0-0.20.2-0.5-0.40.50.50.50.50.50.60.50.70.90.9-1.01.01.01.31.3-1.6
Ambulatory time before self-admin0.30.51.2-0.4-0.00.10.00.6-0.7-0.7-0.6-0.6-0.6-0.7-0.5-0.7-0.9-0.90.9-0.9-0.8-1.0-1.11.0
Ambulatory time after self-admin0.20.21.00.6-1.01.00.9-0.30.20.20.20.20.20.10.30.0-0.1-0.20.2-0.2-0.0-0.6-0.50.6
Bone: tissue strength0.00.00.20.3-0.20.20.40.0-0.0-0.00.00.00.0-0.10.1-0.0-0.2-0.20.2-0.2-0.1-0.4-0.40.3
Total heroin consumption3.03.57.1-2.42.6-2.7-2.42.0-2.0-1.9-1.9-1.9-1.9-1.8-2.0-1.8-1.6-1.51.4-1.4-1.8-0.9-0.81.0
Bone: trabecular number2.64.26.8-1.30.7-0.6-0.62.1-2.1-2.1-2.0-2.0-2.0-2.2-1.8-2.2-2.4-2.42.5-2.5-2.2-2.6-2.62.3
Bone: trabecular spacing0.91.21.80.8-0.0-0.00.4-1.21.21.21.11.11.11.20.91.21.31.3-1.31.31.01.31.3-1.0
Bone: trabecular thickness0.60.72.10.1-0.60.70.60.5-0.5-0.6-0.5-0.5-0.6-0.7-0.3-0.7-0.9-1.01.1-1.1-0.8-1.4-1.41.2
Bone: trabecular tissue density7.310.712.63.5-3.33.23.0-3.53.53.53.53.53.53.53.53.43.33.2-3.23.23.32.72.6-2.5
Water consumed over 24 hours1.11.41.8-1.31.1-1.0-1.11.3-1.3-1.3-1.3-1.3-1.3-1.3-1.1-1.3-1.3-1.21.2-1.2-1.0-1.1-1.10.7
Number of responses in last shaping day0.00.00.3-0.30.4-0.5-0.30.1-0.1-0.00.00.00.0-0.0-0.20.00.10.1-0.10.1-0.30.20.20.2