Hub : Genes

Aldh3b3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression Aldh3b3 0.24 0.14 5.4e-04 0.05 0.05 0.09 0.05 1.6e-02 1.8e-02 2.6e-03 1.8e-02
2 PL intron excision ratio chr1_201198745_201200051 0.03 0.03 7.8e-03 0.02 0.01 0.01 0.01 1.4e-03 9.9e-03 6.1e-02 1.7e-02
3 Brain alternative polyA XM_039101314.1 0.19 0.11 1.2e-11 0.12 0.11 0.14 0.14 2.8e-11 1.3e-10 9.4e-13 1.5e-12
4 Brain alternative polyA XM_039101315.1 0.18 0.1 3.9e-11 0.11 0.11 0.13 0.13 1.0e-10 1.8e-10 2.1e-12 3.8e-12
5 PL intron excision ratio chr1_201196081_201198646 0.04 0.03 2.8e-03 0.02 0.03 0.02 0.02 1.3e-03 6.5e-04 3.6e-03 9.4e-04
6 PL gene expression Aldh3b3 0.78 0.07 0.0e+00 0.56 0.74 0.74 0.74 3.0e-73 1.4e-121 6.2e-120 4.2e-121
7 OFC intron excision ratio chr1_201248714_201250020 0.36 0.18 7.8e-05 0.05 0.12 0.15 0.12 2.1e-02 7.8e-04 2.1e-04 1.1e-03
8 OFC intron excision ratio chr1_201198745_201200051 0.35 0.18 1.1e-04 0.06 0.12 0.15 0.11 1.6e-02 1.0e-03 1.7e-04 1.3e-03
9 OFC gene expression Aldh3b3 0.81 0.09 0.0e+00 0.36 0.52 0.53 0.54 2.5e-09 2.8e-14 7.3e-15 2.8e-15
10 BLA gene expression Aldh3b3 0.75 0.1 0.0e+00 0.38 0.57 0.56 0.58 2.3e-21 3.4e-36 1.5e-35 3.9e-37
11 IL gene expression Aldh3b3 0.84 0.1 0.0e+00 0.22 0.46 0.47 0.49 6.5e-06 1.6e-12 5.5e-13 1.1e-13
12 NAcc gene expression Aldh3b3 0.44 0.15 0.0e+00 0.32 0.41 0.41 0.41 3.3e-37 3.2e-51 1.5e-50 2.6e-51
13 IL alternative polyA XM_039101315.1 0.29 0.17 5.9e-04 0.02 0.1 0.04 0.07 1.2e-01 2.8e-03 4.4e-02 8.9e-03
14 Brain gene expression Aldh3b3 0.72 0.06 0.0e+00 0.44 0.59 0.59 0.58 4.9e-45 2.2e-68 6.4e-67 4.8e-66
15 pVTA gene expression Aldh3b3 0.5 0.2 2.4e-15 0.24 0.28 0.28 0.28 5.3e-11 9.6e-13 2.3e-12 2.5e-12
16 BLA alternative polyA XM_039101314.1 0.25 0.14 2.5e-11 0.12 0.2 0.18 0.2 4.3e-07 9.8e-11 7.3e-10 1.0e-10
17 IL alternative polyA XM_039101314.1 0.23 0.15 2.5e-03 0.02 0.08 0.02 0.05 9.4e-02 6.3e-03 9.0e-02 3.0e-02
18 PL intron excision ratio chr1_201248714_201250020 0.11 0.07 1.9e-10 0.09 0.1 0.09 0.1 3.6e-10 3.5e-11 3.8e-10 7.4e-11
19 OFC alternative polyA XM_039101314.1 0.32 0.17 1.1e-04 0.15 0.18 0.2 0.16 2.1e-04 4.9e-05 1.7e-05 1.2e-04
20 OFC alternative polyA XM_039101315.1 0.33 0.17 8.7e-05 0.16 0.19 0.2 0.16 1.3e-04 3.5e-05 1.4e-05 1.0e-04
21 IL intron excision ratio chr1_201244082_201244258 0.22 0.14 2.6e-03 0.03 0.07 0.04 0.07 8.4e-02 1.1e-02 5.0e-02 1.0e-02
22 LHb gene expression Aldh3b3 0.25 0.15 1.2e-03 0.11 0.09 0.06 0.1 1.3e-03 3.1e-03 1.7e-02 3.0e-03
23 PL intron excision ratio chr1_201244082_201244258 0.31 0.16 0.0e+00 0.19 0.26 0.26 0.26 2.8e-20 1.0e-28 9.9e-29 1.7e-28

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density2.23.77.0-0.40.31.1-1.1-1.7-2.11.41.5-2.0-1.9-2.1-2.02.2-2.2-2.3-2.2-2.3-2.31.6-1.62.62.6-2.6
Area under the delay curve0.50.51.6-0.2-0.10.3-0.3-0.5-0.60.30.3-0.6-0.6-0.6-0.70.8-0.8-0.8-1.1-0.8-0.81.0-1.00.90.9-1.3
BMI with tail3.912.616.32.12.53.3-3.4-3.6-3.73.33.3-3.7-3.7-3.8-3.73.8-3.8-3.8-3.8-3.8-3.84.0-4.03.43.4-3.4
BMI without tail2.34.85.91.21.62.0-2.0-2.3-2.41.92.0-2.3-2.4-2.4-2.42.4-2.4-2.4-2.4-2.4-2.42.2-2.22.22.2-2.1
Body weight2.811.716.44.13.94.0-4.0-4.0-3.73.23.1-3.8-3.7-3.7-3.63.5-3.4-3.3-3.1-3.2-3.23.5-3.52.22.2-1.9
Weight adjusted by age1.11.22.91.51.71.6-1.6-1.2-1.11.41.3-1.0-1.0-0.9-1.00.9-0.9-0.9-0.8-0.8-0.81.1-1.10.40.4-0.3
Bone surface4.58.09.61.11.92.5-2.6-2.9-3.12.82.9-3.0-2.9-3.0-3.03.1-3.0-3.1-3.0-3.1-3.12.7-2.73.03.0-2.9
Bone volume2.23.75.80.10.81.3-1.4-1.8-2.11.92.0-2.0-1.9-2.1-2.02.1-2.1-2.2-2.1-2.2-2.21.8-1.82.42.4-2.4
Breakpoint value in progressive ratio session1.81.92.91.71.71.7-1.7-1.6-1.51.41.4-1.5-1.5-1.5-1.41.4-1.3-1.3-1.5-1.3-1.31.2-1.20.90.9-0.7
Number of licking bursts0.10.10.2-0.00.20.3-0.3-0.3-0.30.40.4-0.3-0.3-0.2-0.30.3-0.3-0.3-0.5-0.3-0.30.3-0.30.40.4-0.3
Context. condit. distance diff. score0.40.51.3-1.1-1.2-1.01.00.90.6-0.9-0.90.80.70.70.7-0.60.60.50.50.50.5-0.50.5-0.0-0.00.0
Locomotion velocity, session 10.00.00.00.00.00.0-0.0-0.1-0.1-0.1-0.1-0.0-0.0-0.0-0.00.1-0.0-0.10.0-0.1-0.10.1-0.10.10.1-0.0
Locomotion distance, session 11.82.33.00.40.81.4-1.4-1.4-1.61.41.4-1.4-1.5-1.5-1.61.6-1.6-1.7-1.7-1.7-1.71.7-1.71.71.7-1.7
Locomotion velocity, session 21.61.83.51.81.91.8-1.8-1.6-1.41.41.4-1.4-1.4-1.3-1.41.3-1.2-1.2-1.1-1.1-1.11.2-1.20.60.6-0.4
Locomotion distance, session 21.52.13.20.91.41.6-1.6-1.5-1.51.81.8-1.4-1.5-1.4-1.51.5-1.5-1.5-1.5-1.4-1.41.5-1.51.21.2-1.1
Locomotion velocity, session 31.01.22.4-0.3-0.20.4-0.4-0.9-1.10.50.6-1.0-1.1-1.1-1.11.2-1.3-1.3-1.3-1.3-1.31.2-1.21.51.5-1.5
Locomotion distance, session 30.10.10.2-0.00.00.1-0.2-0.2-0.30.30.3-0.2-0.2-0.2-0.20.3-0.3-0.3-0.3-0.3-0.30.4-0.40.40.4-0.3
Stereotopy head waving bouts, day 30.50.61.8-1.1-0.8-0.20.2-0.3-0.5-0.2-0.1-0.6-0.5-0.6-0.60.7-0.8-0.8-0.9-0.8-0.80.6-0.61.21.2-1.4
Stereotopy head waving duration, day 30.30.32.2-1.5-1.2-0.80.80.50.3-0.6-0.50.20.20.20.1-0.10.0-0.0-0.2-0.1-0.1-0.20.10.60.6-0.7
Locomotion velocity, session 70.70.71.5-0.2-0.00.5-0.5-0.6-0.80.40.5-0.7-0.8-0.8-0.80.9-0.9-1.0-1.0-1.0-1.01.0-1.01.21.2-1.2
Locomotion distance, session 70.40.50.80.50.70.9-0.9-0.7-0.70.60.7-0.7-0.7-0.7-0.70.7-0.7-0.7-0.6-0.7-0.70.7-0.70.60.6-0.6
Stereotopy head waving bouts, day 70.30.41.3-1.2-1.0-0.50.5-0.0-0.2-0.1-0.0-0.2-0.3-0.3-0.40.4-0.5-0.5-0.7-0.6-0.60.5-0.51.01.0-1.1
Stereotopy head waving duration, day 72.02.43.70.30.51.0-1.0-1.5-1.61.21.2-1.6-1.7-1.6-1.81.7-1.8-1.7-1.9-1.8-1.81.7-1.71.81.8-1.8
Locomotion velocity, session 81.01.22.01.41.41.3-1.3-1.3-1.31.11.0-1.2-1.2-1.2-1.11.1-1.0-1.0-0.8-1.0-1.01.0-1.00.60.6-0.5
Locomotion distance, session 80.00.10.3-0.5-0.3-0.10.10.1-0.10.20.20.10.0-0.0-0.00.1-0.1-0.2-0.2-0.2-0.20.2-0.20.50.5-0.5
Degree of sensitization distance0.50.60.70.30.60.8-0.8-0.7-0.80.60.6-0.8-0.7-0.8-0.80.8-0.8-0.8-0.8-0.8-0.80.7-0.70.70.7-0.8
Degree of sensitization stereotypy0.70.81.20.10.20.5-0.5-0.8-0.90.70.7-0.9-1.0-0.9-1.01.0-1.0-1.0-1.1-1.0-1.00.9-0.91.11.1-1.0
Conditioned locomotion0.60.74.12.02.01.2-1.1-0.7-0.31.11.0-0.3-0.4-0.2-0.2-0.00.10.10.20.20.2-0.00.1-1.0-1.01.2
Cocaine response after cond. corrected0.10.10.5-0.5-0.6-0.50.50.20.2-0.7-0.70.20.20.20.1-0.10.10.10.10.10.1-0.20.20.10.1-0.1
Cocaine response after cond. not corrected0.10.10.3-0.6-0.5-0.30.3-0.0-0.1-0.2-0.2-0.1-0.1-0.2-0.20.2-0.3-0.3-0.3-0.3-0.30.2-0.20.50.5-0.6
Cocaine response before conditioning0.30.31.00.20.40.5-0.5-0.5-0.51.01.0-0.5-0.5-0.5-0.50.5-0.6-0.5-0.6-0.5-0.50.6-0.60.50.5-0.5
Saline control response2.12.74.32.02.12.0-2.0-1.9-1.81.81.7-1.8-1.8-1.7-1.71.6-1.6-1.6-1.5-1.5-1.51.5-1.50.90.9-0.8
Bone: connectivity density4.77.49.60.71.52.3-2.4-2.8-3.02.22.3-3.0-2.9-3.0-3.03.1-3.0-3.1-3.0-3.1-3.12.3-2.43.03.0-3.0
Bone: cortical apparent density0.20.31.01.00.90.9-0.9-0.7-0.50.30.3-0.5-0.6-0.5-0.50.4-0.4-0.3-0.4-0.3-0.30.4-0.4-0.0-0.00.1
Bone: cortical area0.10.20.91.00.90.4-0.4-0.3-0.10.50.5-0.2-0.2-0.1-0.1-0.00.10.10.20.20.2-0.20.2-0.5-0.50.6
Bone: cortical porosity0.10.10.20.1-0.2-0.10.1-0.2-0.3-0.1-0.1-0.2-0.2-0.2-0.20.2-0.2-0.2-0.2-0.3-0.20.4-0.40.30.3-0.3
Bone: cortical porosity0.20.20.60.80.40.4-0.4-0.6-0.60.30.3-0.6-0.6-0.6-0.60.5-0.5-0.5-0.4-0.5-0.50.7-0.70.30.3-0.3
Bone: cortical thickness1.11.89.13.02.92.0-1.9-1.4-0.91.61.5-1.1-1.1-0.9-0.90.5-0.4-0.3-0.3-0.2-0.20.3-0.3-0.9-0.91.2
Bone: cortical thickness0.70.83.51.51.91.4-1.4-1.0-0.71.41.4-0.9-0.9-0.7-0.80.6-0.5-0.5-0.4-0.4-0.40.2-0.2-0.2-0.20.4
Bone: cortical tissue density0.30.31.21.11.01.0-1.0-0.7-0.50.40.4-0.6-0.6-0.5-0.50.4-0.4-0.4-0.4-0.3-0.30.5-0.5-0.1-0.10.1
Condit. Reinf. active minus inactive responses0.40.40.70.10.20.5-0.5-0.6-0.70.40.4-0.6-0.7-0.6-0.70.7-0.7-0.7-0.8-0.8-0.80.8-0.80.80.8-0.7
Condit. Reinf. active-inactive response ratio0.10.10.3-0.2-0.20.0-0.0-0.2-0.3-0.0-0.0-0.2-0.3-0.2-0.30.3-0.3-0.4-0.4-0.4-0.40.4-0.40.50.5-0.5
Condit. Reinf. active responses0.00.00.1-0.10.00.2-0.2-0.1-0.10.10.1-0.1-0.2-0.1-0.20.2-0.2-0.2-0.2-0.2-0.20.3-0.30.20.2-0.2
Condit. Reinf. inactive responses0.10.10.3-0.1-0.2-0.20.20.30.3-0.3-0.30.40.30.40.3-0.30.30.30.50.30.3-0.20.2-0.3-0.30.4
Incentive salience index mean0.40.40.70.30.50.7-0.7-0.6-0.70.70.7-0.6-0.6-0.6-0.70.7-0.7-0.7-0.7-0.7-0.70.8-0.80.70.7-0.6
Condit. Reinf. lever presses0.10.10.30.40.50.5-0.5-0.0-0.00.50.50.00.10.10.1-0.10.10.10.10.10.10.1-0.1-0.2-0.20.2
Condit. Reinf. active minus inactive responses0.30.41.5-1.2-1.0-0.50.40.0-0.2-0.2-0.1-0.2-0.2-0.3-0.30.4-0.5-0.5-0.5-0.6-0.60.5-0.51.01.0-1.1
Condit. Reinf. active-inactive response ratio0.60.63.0-1.7-1.6-1.21.20.90.6-0.9-0.90.70.70.60.6-0.40.40.30.30.30.3-0.40.40.30.3-0.4
Condit. Reinf. active responses0.81.12.8-0.6-0.40.3-0.3-0.7-1.00.60.7-0.9-0.9-1.0-1.01.1-1.2-1.2-1.2-1.3-1.31.2-1.21.61.6-1.7
Condit. Reinf. inactive responses1.72.22.50.80.91.3-1.3-1.5-1.51.41.4-1.5-1.5-1.6-1.61.6-1.6-1.6-1.6-1.6-1.61.6-1.61.51.5-1.5
Condit. Reinf. lever presses1.52.12.60.81.11.3-1.3-1.4-1.51.61.6-1.5-1.5-1.5-1.51.5-1.5-1.5-1.5-1.5-1.51.4-1.41.41.4-1.4
Condit. Reinf. lever reinforcers received1.11.53.2-0.4-0.10.5-0.6-1.0-1.20.70.8-1.1-1.2-1.2-1.21.4-1.4-1.4-1.4-1.5-1.51.4-1.41.71.7-1.8
Conditioned reinforcement - actives0.80.81.0-0.2-0.5-0.70.70.91.0-0.9-0.90.91.01.01.0-1.01.01.01.01.01.0-0.90.9-1.0-1.00.7
Conditioned reinforcement - inactives4.34.98.5-2.7-2.9-2.62.62.62.5-2.3-2.32.42.42.32.3-2.22.02.01.92.02.0-2.02.0-1.3-1.30.6
Conditioned locomotion9.311.214.8-2.8-3.2-3.63.63.83.8-3.1-3.13.83.83.73.7-3.63.53.53.33.43.4-3.13.1-2.7-2.72.4
Patch foraging indifference point 0 sec0.30.41.4-0.7-1.2-1.21.10.60.5-1.0-1.00.50.50.50.5-0.50.40.40.40.40.4-0.20.2-0.1-0.1-0.0
Patch foraging indifference point AUC0.70.85.32.31.51.3-1.3-0.9-0.70.80.8-0.6-0.6-0.5-0.50.5-0.4-0.4-0.5-0.3-0.30.9-0.9-0.2-0.20.3
Delay disc. indifference point, 0s delay1.01.12.8-0.2-0.20.3-0.3-0.7-1.00.70.7-0.9-1.0-1.1-1.11.1-1.2-1.2-1.3-1.2-1.21.3-1.31.51.5-1.7
Delay disc. indifference point, 16s delay0.60.61.6-1.2-1.3-1.11.11.00.9-0.9-0.90.90.80.90.8-0.70.70.60.40.60.6-0.30.3-0.2-0.20.0
Delay disc. indifference point, 2s delay0.10.10.5-0.7-0.5-0.10.10.1-0.0-0.2-0.1-0.0-0.0-0.1-0.10.2-0.2-0.2-0.4-0.3-0.30.3-0.30.60.6-0.7
Delay disc. indifference point, 24s delay0.10.10.30.4-0.0-0.20.20.00.1-0.5-0.50.10.10.10.1-0.20.20.20.20.30.3-0.30.3-0.4-0.40.4
Delay disc. indifference point, 4s delay0.40.41.10.40.20.5-0.5-0.4-0.60.50.5-0.4-0.5-0.5-0.50.6-0.6-0.6-0.8-0.6-0.61.0-1.00.60.6-0.8
Delay disc. indifference point, 8s delay0.40.40.80.00.00.3-0.3-0.5-0.60.10.1-0.6-0.6-0.6-0.70.7-0.7-0.7-0.9-0.7-0.70.7-0.70.70.7-0.9
Indifference point function ln k3.65.19.7-3.1-3.0-2.82.72.52.3-2.8-2.82.32.22.22.2-2.01.91.91.91.91.9-2.32.3-1.1-1.10.8
Indifference point function log k3.65.19.7-3.1-3.0-2.82.72.52.3-2.8-2.82.32.22.22.2-2.01.91.91.91.91.9-2.32.3-1.1-1.10.8
Patch foraging total patch changes 0 sec0.30.41.2-0.3-0.9-1.01.00.60.6-1.1-1.10.60.50.50.5-0.60.60.60.70.60.6-0.30.3-0.5-0.50.4
Patch foraging total patch changes 12 sec1.62.06.02.51.91.7-1.6-1.6-1.51.51.4-1.4-1.4-1.3-1.31.3-1.2-1.2-1.3-1.2-1.21.6-1.60.50.5-0.5
Patch foraging total patch changes 18 sec0.30.41.00.90.50.5-0.5-0.6-0.70.30.3-0.6-0.6-0.6-0.60.6-0.5-0.6-0.5-0.6-0.61.0-1.00.40.4-0.5
Patch foraging total patch changes 24 sec0.30.32.51.61.00.7-0.7-0.7-0.60.30.3-0.5-0.5-0.4-0.40.4-0.3-0.3-0.5-0.3-0.30.4-0.4-0.2-0.20.3
Patch foraging total patch changes 6 sec1.01.52.31.20.50.9-0.9-1.3-1.40.60.6-1.3-1.4-1.4-1.41.3-1.3-1.3-1.4-1.3-1.31.5-1.51.11.1-1.1
Patch foraging time to switch 0 sec3.75.67.70.71.82.2-2.2-2.3-2.42.72.8-2.4-2.4-2.4-2.52.5-2.5-2.5-2.7-2.5-2.52.2-2.22.42.4-2.4
Patch foraging water rate 0 sec7.211.613.8-1.6-2.8-3.43.43.53.6-3.5-3.63.63.73.63.7-3.63.63.63.73.63.6-3.23.2-3.2-3.23.1
Patch foraging water rate 12 sec9.614.717.9-2.2-3.3-3.83.84.04.0-4.1-4.13.94.14.04.1-4.04.14.04.24.04.0-3.83.8-3.4-3.43.4
Patch foraging water rate 18 sec2.02.63.6-1.2-1.6-1.71.71.81.8-1.9-1.91.61.71.61.7-1.71.71.71.81.61.6-1.61.6-1.2-1.21.1
Patch foraging water rate 24 sec4.36.07.9-1.2-1.8-2.32.42.42.6-2.5-2.52.52.62.52.6-2.62.62.62.82.62.6-2.52.5-2.4-2.42.4
Patch foraging water rate 6 sec3.44.97.2-0.8-1.5-1.91.92.22.3-2.4-2.42.22.32.22.3-2.42.42.42.72.42.4-2.42.4-2.2-2.22.2
Seeking ratio, delayed vs. immediate footshock0.60.61.2-0.1-0.10.4-0.4-0.7-0.80.20.2-0.8-0.9-0.9-0.90.9-1.0-0.9-1.0-1.0-1.00.8-0.81.11.1-1.0
Distance traveled before self-admin0.10.20.30.10.20.4-0.4-0.5-0.50.00.0-0.5-0.4-0.4-0.40.5-0.4-0.5-0.5-0.5-0.50.2-0.20.40.4-0.3
Distance traveled after self-admin0.10.10.5-0.7-0.00.1-0.1-0.1-0.20.20.2-0.3-0.1-0.2-0.20.2-0.2-0.2-0.1-0.2-0.2-0.30.30.30.3-0.1
Extensor digitorum longus weight3.714.537.05.76.15.2-5.2-4.4-3.74.44.3-4.0-3.9-3.7-3.73.3-3.2-3.1-3.0-2.9-2.93.3-3.31.21.2-0.8
Bone: elastic displacement2.12.44.40.4-0.3-1.11.11.31.5-1.2-1.31.51.51.51.6-1.71.71.81.91.81.8-1.61.6-2.1-2.12.1
Bone: elastic work0.30.43.11.71.30.7-0.7-0.6-0.30.10.1-0.4-0.4-0.3-0.30.00.00.10.30.20.20.00.0-0.8-0.81.0
Bone: endosteal estimation0.30.73.5-1.9-1.9-1.31.30.90.4-0.9-0.80.60.70.50.5-0.20.20.10.10.0-0.00.1-0.10.80.8-1.0
Bone: endosteal perimeter0.71.57.9-2.8-2.7-2.01.91.30.7-1.1-1.00.91.00.70.8-0.40.30.20.20.00.0-0.00.01.11.1-1.3
Epididymis fat weight2.14.88.5-2.9-2.9-2.92.92.72.5-2.2-2.22.42.42.32.3-2.12.02.01.81.91.9-1.71.7-1.1-1.10.7
Delta time in closed arm before/after self-admin0.30.32.61.61.10.8-0.8-0.6-0.40.40.4-0.4-0.4-0.3-0.30.3-0.3-0.2-0.3-0.2-0.10.3-0.2-0.2-0.20.1
Delta time in open arm before/after self-admin0.10.00.4-0.6-0.4-0.30.30.30.2-0.1-0.10.20.20.10.2-0.10.10.10.00.10.1-0.10.10.10.1-0.1
Diff in mean of infusions in LGA sessions0.10.10.60.80.70.6-0.6-0.5-0.40.10.1-0.4-0.4-0.3-0.30.3-0.2-0.3-0.2-0.2-0.2-0.00.0-0.0-0.00.1
Delay discount exponential model param0.40.41.20.10.1-0.30.40.50.6-0.2-0.20.50.60.60.6-0.70.70.71.00.70.8-0.90.9-0.8-0.81.1
Extinction: sum of active levers before priming3.93.95.42.01.92.2-2.2-2.3-2.31.51.5-2.2-2.2-2.1-2.12.1-2.0-2.1-2.0-2.0-2.01.8-1.81.51.5-1.1
Active lever presses in extinction session 60.30.32.41.61.30.9-0.8-0.4-0.00.50.5-0.2-0.1-0.10.0-0.10.10.20.10.30.3-0.10.1-0.6-0.60.7
Bone: final force1.62.53.41.41.81.8-1.8-1.8-1.71.81.9-1.7-1.8-1.7-1.71.6-1.5-1.6-1.5-1.5-1.51.2-1.21.11.1-1.0
Bone: final moment1.32.12.81.31.71.6-1.6-1.6-1.61.71.7-1.6-1.6-1.5-1.61.5-1.4-1.4-1.3-1.4-1.41.1-1.11.01.0-0.9
Food consumed during 24 hour testing period0.50.60.8-0.5-0.4-0.80.80.80.8-0.3-0.40.80.80.90.9-0.80.90.80.80.80.8-0.90.9-0.7-0.70.8
Glucose0.40.53.6-1.9-1.6-0.90.90.70.3-0.6-0.50.40.50.30.3-0.00.0-0.1-0.2-0.2-0.20.1-0.10.90.9-1.1
Heart weight0.81.23.1-1.7-1.8-1.51.51.20.9-1.7-1.61.01.11.01.1-0.80.80.70.60.70.7-0.70.7-0.3-0.30.1
Delay discount hyperbolic model param0.40.41.30.0-0.0-0.40.40.50.6-0.3-0.30.50.60.60.6-0.70.70.71.00.80.8-0.90.9-0.8-0.81.1
Intermittent access intake day 1-15 change2.32.33.1-1.5-1.4-1.51.51.61.5-1.8-1.71.61.61.61.5-1.51.61.51.51.51.5-1.71.7-1.2-1.21.0
Intermittent access intake escalation1.71.62.5-1.6-1.4-1.31.31.41.3-1.6-1.51.31.31.31.3-1.21.31.21.31.11.1-1.41.4-0.8-0.80.6
Intermittent access intake escalation 21.11.11.6-1.0-1.1-1.01.11.11.0-1.3-1.21.11.01.11.0-1.01.11.01.21.01.0-1.11.1-0.8-0.80.8
Intermitt. access day 1 inactive lever presses0.90.92.3-1.5-1.5-1.41.41.21.2-0.9-0.91.11.01.01.0-0.90.70.90.60.80.8-0.40.4-0.4-0.40.4
Intermitt. access day 15 inactive lever presses0.91.05.2-2.3-1.8-1.41.41.21.1-1.0-0.90.90.80.80.8-0.70.60.60.50.60.6-0.80.8-0.1-0.1-0.1
Intermitt. access escalation Index2.72.43.2-1.2-1.6-1.71.71.81.6-1.6-1.71.71.81.71.8-1.61.61.51.61.51.5-1.21.2-1.1-1.11.0
Intermittent access day 1 total infusions0.91.08.6-2.9-2.0-1.21.10.70.5-0.3-0.20.20.20.00.00.2-0.4-0.3-0.7-0.4-0.40.2-0.21.21.2-1.7
Intermittent access day 15 total infusions3.64.114.4-3.8-3.2-2.72.72.42.2-2.3-2.22.02.01.91.8-1.71.51.51.21.41.4-1.71.7-0.4-0.4-0.1
Intermittent access terminal intake (last 3 days)1.92.110.5-3.2-2.7-2.02.01.71.5-1.6-1.51.41.31.21.1-1.00.90.90.50.80.7-1.01.00.10.1-0.5
Intermittent access total infusions0.80.96.4-2.5-2.0-1.41.41.21.0-0.8-0.70.80.80.70.6-0.50.40.40.00.30.3-0.30.30.40.4-0.8
Intermittent access day 1 locomotion0.60.72.4-1.5-1.0-0.30.30.1-0.00.40.4-0.2-0.3-0.4-0.40.5-0.8-0.6-1.1-0.7-0.71.0-1.01.21.2-1.5
Intermittent access day 15 total locomotion2.02.16.3-2.5-2.2-1.91.81.91.6-1.5-1.51.61.51.51.4-1.31.21.21.01.11.1-1.11.1-0.4-0.4-0.1
Intermittent access total locomotion1.31.59.5-3.1-2.4-1.71.71.61.4-0.9-0.91.21.11.01.0-0.80.60.60.30.50.5-0.50.40.40.4-0.9
Intermittent access standard deviation0.80.81.5-1.2-1.1-1.01.01.01.0-0.9-0.81.00.90.90.8-0.90.90.80.80.80.8-1.11.1-0.6-0.60.2
Left kidney weight1.33.65.4-1.2-1.9-2.32.32.02.0-2.1-2.22.02.12.02.1-2.01.91.91.91.91.9-1.51.5-1.6-1.61.5
Right kidney weight1.44.04.9-0.6-1.5-2.12.12.12.1-2.0-2.02.12.22.22.2-2.12.12.12.12.12.1-1.71.7-2.0-2.01.9
Cocaine induced anxiety0.00.10.3-0.3-0.2-0.10.10.10.1-0.2-0.20.10.30.10.2-0.10.10.10.30.10.1-0.50.5-0.1-0.1-0.2
Post-drug Anxiety0.20.21.01.00.80.6-0.6-0.7-0.50.10.1-0.5-0.5-0.5-0.40.3-0.2-0.20.1-0.2-0.2-0.20.2-0.2-0.20.2
Baseline Anxiety0.70.73.01.71.31.2-1.1-1.1-1.00.70.6-0.9-1.0-0.8-0.90.7-0.6-0.6-0.4-0.5-0.50.7-0.6-0.0-0.00.4
Tail length0.10.42.21.51.30.8-0.7-0.6-0.30.20.2-0.4-0.3-0.2-0.20.00.00.10.20.20.2-0.50.5-0.8-0.81.0
Length with tail0.72.711.73.43.02.4-2.3-2.1-1.71.41.4-1.8-1.7-1.5-1.51.3-1.2-1.1-0.8-0.9-0.91.0-1.0-0.2-0.20.5
Length without tail1.12.57.82.82.32.1-2.1-2.0-1.71.31.3-1.8-1.6-1.6-1.51.4-1.3-1.3-1.0-1.2-1.21.6-1.60.40.4-0.2
Times rat made contact with spout1.01.11.60.50.60.8-0.8-1.1-1.20.90.9-1.2-1.2-1.2-1.21.2-1.2-1.2-1.1-1.2-1.21.1-1.11.11.1-1.1
Lifetime Intake0.60.75.1-2.3-1.8-1.21.21.00.8-0.6-0.60.60.60.50.4-0.40.20.2-0.10.10.1-0.10.10.50.5-0.9
Liver weight, left0.10.20.8-0.9-0.2-0.50.50.40.4-0.1-0.10.40.50.40.5-0.40.40.40.40.40.3-0.80.8-0.2-0.20.1
Liver weight, right0.30.50.80.0-0.0-0.60.60.60.7-0.4-0.40.70.70.70.8-0.80.70.80.80.80.8-0.70.7-0.9-0.90.8
Locomotor activity1.21.93.3-1.1-1.4-1.51.51.31.3-1.8-1.81.31.41.31.4-1.31.31.31.41.31.3-1.61.6-1.1-1.11.0
Locomotor testing distance1.42.44.9-1.3-1.8-1.81.81.51.4-2.2-2.21.51.51.51.5-1.41.41.41.41.41.4-1.81.8-1.2-1.21.0
Locomotor testing rearing0.40.62.6-1.6-1.5-1.11.00.80.6-1.3-1.30.60.60.50.5-0.40.40.40.40.30.3-0.70.70.20.2-0.4
Locomotion in novel chamber3.54.313.6-3.7-3.0-2.72.72.52.2-2.2-2.12.22.12.01.9-1.81.71.71.41.61.6-2.22.1-0.7-0.70.3
Locomotion in novel chamber post-restriction2.32.84.9-2.2-2.1-2.22.21.91.8-1.7-1.71.71.61.61.6-1.61.51.51.51.51.5-1.91.9-0.9-0.90.4
Fecal boli incidents, locomotor time 10.00.00.1-0.4-0.1-0.10.10.20.30.20.20.20.20.20.2-0.20.10.20.10.10.10.1-0.1-0.2-0.2-0.1
Change in fecal boli incidents, locomotor task0.40.40.60.30.40.6-0.6-0.7-0.70.30.3-0.7-0.6-0.7-0.70.7-0.7-0.7-0.7-0.7-0.70.4-0.40.50.5-0.8
Time >=10cm from walls, locomotor time 10.60.64.6-2.1-1.2-0.60.50.3-0.00.10.2-0.10.0-0.1-0.10.4-0.5-0.5-0.5-0.6-0.60.0-0.01.01.0-1.7
Bouts of movement, locomotor time 10.20.22.61.61.00.6-0.6-0.4-0.30.10.1-0.3-0.1-0.0-0.00.00.10.00.30.10.1-0.10.1-0.5-0.50.4
Total resting periods, locomotor time 10.10.21.41.20.60.3-0.3-0.1-0.1-0.1-0.1-0.00.10.20.2-0.20.30.20.50.30.3-0.30.3-0.6-0.60.5
Rest time, locomotor task time 12.62.83.9-1.0-1.3-1.71.71.71.7-1.5-1.51.81.81.71.8-1.81.81.71.81.71.7-2.02.0-1.7-1.71.3
Distance moved, locomotor task time 10.80.91.8-0.20.20.6-0.6-0.8-0.80.60.6-0.9-0.9-0.9-1.01.0-1.1-1.1-1.3-1.1-1.11.3-1.31.21.2-1.1
Vertical activity count, locomotor time 10.40.42.0-1.4-1.2-0.90.90.70.6-0.9-0.90.50.40.40.4-0.30.20.2-0.00.20.2-0.10.10.30.3-0.2
Time >=10cm from walls, locomotor time 20.20.20.4-0.2-0.3-0.40.40.50.6-0.1-0.20.50.60.60.6-0.60.50.60.60.60.5-0.10.2-0.7-0.70.6
Bouts of movement, locomotor time 20.30.31.21.10.80.7-0.7-0.6-0.50.80.7-0.4-0.4-0.4-0.40.4-0.4-0.4-0.5-0.3-0.30.9-0.9-0.0-0.00.1
Total resting periods, locomotor time 20.20.20.70.80.50.4-0.4-0.5-0.40.60.5-0.4-0.4-0.3-0.30.4-0.4-0.3-0.5-0.3-0.30.8-0.80.10.1-0.0
Rest time, locomotor task time 20.70.83.9-2.0-1.6-1.41.41.00.8-0.7-0.70.80.80.60.6-0.50.50.40.40.40.4-0.90.90.20.2-0.6
Distance moved, locomotor task time 20.20.21.71.30.90.7-0.7-0.4-0.30.10.1-0.2-0.3-0.1-0.20.1-0.1-0.0-0.10.00.00.4-0.4-0.4-0.40.8
Vertical activity count, locomotor time 20.91.03.50.80.2-0.30.40.60.8-0.8-0.80.90.80.90.9-1.11.11.21.21.21.2-0.70.7-1.5-1.51.9
Light reinforcement 10.71.31.9-0.6-0.8-1.21.21.31.3-1.0-1.01.41.21.41.2-1.31.31.21.01.21.2-1.11.1-1.0-1.01.0
Light reinforcement 22.53.34.8-1.4-1.8-2.22.22.12.0-1.7-1.72.01.92.01.9-2.02.01.91.91.91.9-1.51.5-1.4-1.41.3
Bone: marrow area0.30.73.5-1.9-1.9-1.31.30.90.5-0.9-0.90.60.70.50.5-0.20.20.10.10.00.00.1-0.10.80.8-1.0
Bone: maximum diameter0.20.30.4-0.2-0.4-0.60.60.60.6-0.5-0.50.60.60.60.6-0.60.60.60.60.60.6-0.50.5-0.5-0.50.5
Bone: maximum force3.25.46.41.21.62.1-2.1-2.4-2.52.22.2-2.5-2.5-2.5-2.52.5-2.5-2.5-2.4-2.5-2.52.4-2.42.42.4-2.3
Bone: maximum moment2.64.55.41.21.41.9-1.9-2.2-2.32.02.0-2.3-2.3-2.3-2.32.3-2.3-2.3-2.2-2.3-2.32.2-2.22.22.2-2.1
Mean time between licks in bursts0.40.51.21.10.80.9-0.9-1.0-0.90.10.2-0.9-0.9-0.8-0.90.8-0.8-0.7-0.6-0.7-0.70.6-0.60.30.3-0.2
Mean num. licks in bursts0.10.10.20.1-0.2-0.00.0-0.3-0.4-0.2-0.2-0.3-0.3-0.4-0.30.3-0.4-0.3-0.1-0.3-0.30.3-0.30.40.4-0.4
Cd content in liver1.51.62.2-1.2-1.4-1.41.41.51.4-1.1-1.11.41.51.41.4-1.41.31.31.41.31.3-1.11.1-0.9-0.90.9
Co content in liver1.01.22.00.1-0.2-0.80.81.01.2-0.6-0.61.21.21.21.2-1.21.31.31.31.31.3-1.01.0-1.4-1.41.4
Cu content in liver0.10.10.30.60.40.3-0.3-0.2-0.20.30.3-0.2-0.2-0.2-0.10.1-0.1-0.1-0.1-0.1-0.10.3-0.3-0.1-0.10.2
Fe content in liver0.00.00.10.30.10.3-0.2-0.2-0.2-0.3-0.3-0.1-0.1-0.1-0.10.1-0.1-0.1-0.2-0.1-0.10.1-0.1-0.0-0.0-0.0
K content in liver3.23.23.61.11.11.6-1.6-1.8-1.91.81.8-1.9-1.9-1.9-1.91.9-1.9-1.9-1.9-1.9-1.91.9-1.91.91.9-1.7
Mg content in liver2.12.14.3-0.30.00.6-0.7-1.0-1.31.41.4-1.3-1.3-1.4-1.41.5-1.5-1.6-1.6-1.6-1.61.7-1.72.12.1-2.0
Mn content in liver1.51.73.61.41.81.4-1.4-1.3-1.21.91.8-1.3-1.3-1.2-1.21.2-1.2-1.1-1.1-1.1-1.11.3-1.30.80.8-0.6
Na content in liver0.20.20.40.40.0-0.10.10.20.2-0.4-0.40.30.20.30.3-0.40.40.40.30.40.4-0.60.6-0.6-0.60.7
Rb content in liver0.50.62.7-1.6-1.4-0.80.70.2-0.1-0.1-0.1-0.1-0.1-0.3-0.20.4-0.5-0.5-0.5-0.6-0.60.7-0.71.31.3-1.5
Se content in liver0.20.30.8-0.9-0.6-0.10.1-0.1-0.3-0.00.0-0.2-0.3-0.3-0.30.4-0.5-0.5-0.7-0.5-0.50.2-0.20.90.9-0.9
Sr content in liver0.70.63.11.61.81.3-1.2-0.8-0.51.01.0-0.7-0.7-0.5-0.60.3-0.3-0.2-0.2-0.2-0.20.1-0.1-0.4-0.40.6
Zn content in liver0.60.71.41.01.21.0-1.0-0.9-0.81.21.2-0.9-0.9-0.8-0.80.7-0.7-0.7-0.5-0.6-0.60.6-0.60.40.4-0.2
Bone: minimum diameter0.40.72.4-1.5-1.4-0.80.70.2-0.3-0.1-0.1-0.1-0.1-0.3-0.30.5-0.6-0.6-0.6-0.7-0.70.7-0.71.41.4-1.6
Time in familiar zone, hab. session 10.10.10.6-0.8-0.7-0.40.40.30.2-0.4-0.40.20.30.20.2-0.10.10.00.10.00.0-0.00.00.30.3-0.3
Time in novel zone, hab. session 10.00.00.10.30.10.00.0-0.10.0-0.1-0.10.0-0.0-0.0-0.0-0.00.00.1-0.00.10.1-0.10.1-0.2-0.20.2
Total zone transitions, hab. session 10.60.92.20.81.11.2-1.2-0.9-0.91.51.5-0.9-0.9-0.8-0.90.9-0.9-0.8-0.9-0.8-0.80.9-0.90.60.6-0.6
Total locomotion distance, hab. session 10.10.21.0-1.0-0.5-0.40.40.60.5-0.1-0.00.50.50.50.5-0.40.30.30.20.30.3-0.20.20.00.0-0.1
Locomotion velocity, hab. session 10.00.00.2-0.5-0.00.0-0.00.30.30.30.30.30.20.30.2-0.20.10.20.00.10.1-0.10.1-0.0-0.0-0.0
Time in familiar zone, hab. session 20.10.11.11.10.80.4-0.4-0.3-0.10.10.0-0.2-0.1-0.1-0.1-0.00.10.10.30.20.2-0.10.1-0.5-0.50.6
Time in novel zone, hab. session 20.50.51.3-0.6-0.40.1-0.1-0.4-0.50.30.3-0.5-0.5-0.6-0.60.7-0.8-0.8-0.9-0.8-0.80.8-0.81.11.1-1.1
Total zone transitions, hab. session 24.86.27.90.71.42.1-2.2-2.3-2.52.82.8-2.4-2.4-2.5-2.52.6-2.6-2.7-2.8-2.7-2.72.6-2.62.72.7-2.7
Total locomotion distance, hab. session 20.91.12.2-0.50.20.7-0.7-0.7-0.91.11.2-0.9-0.9-0.9-1.01.1-1.1-1.2-1.2-1.2-1.21.1-1.11.41.4-1.5
Locomotion velocity, hab. session 20.50.71.8-0.8-0.10.4-0.4-0.4-0.60.80.9-0.6-0.6-0.6-0.70.8-0.9-0.9-1.0-0.9-0.90.9-0.91.31.3-1.3
Novel to familiar place preference ratio0.50.60.8-0.00.40.6-0.6-0.6-0.70.80.8-0.7-0.8-0.7-0.90.8-0.8-0.8-0.9-0.8-0.80.8-0.80.90.9-0.9
Novelty place preference0.30.30.7-0.40.00.3-0.3-0.4-0.50.50.6-0.5-0.6-0.5-0.70.6-0.6-0.6-0.7-0.7-0.70.6-0.60.80.8-0.8
Time in novel zone, NPP test0.40.40.7-0.30.00.3-0.3-0.4-0.50.50.6-0.5-0.7-0.6-0.70.6-0.7-0.7-0.7-0.7-0.70.7-0.70.80.8-0.8
Total zone transitions, NPP test2.13.04.61.01.62.0-2.0-1.7-1.82.12.1-1.7-1.7-1.7-1.71.8-1.7-1.8-1.7-1.7-1.81.8-1.81.61.6-1.5
Total locomotion distance, NPP test0.20.30.5-0.30.30.5-0.6-0.3-0.40.60.7-0.4-0.3-0.3-0.40.5-0.5-0.5-0.6-0.5-0.50.6-0.60.70.7-0.7
Locomotion velocity, NPP test0.10.10.3-0.30.20.4-0.4-0.1-0.20.50.6-0.2-0.2-0.2-0.20.3-0.3-0.3-0.4-0.3-0.40.4-0.40.50.5-0.5
Intraocular pressure1.31.82.3-0.4-0.6-1.11.21.31.4-0.9-1.01.41.41.41.4-1.51.51.51.51.51.5-1.41.4-1.5-1.51.5
Delta distance traveled before/after self-admin0.00.00.4-0.7-0.0-0.00.00.10.10.10.20.00.10.00.1-0.10.10.10.20.10.1-0.40.4-0.0-0.00.1
Delta ambulatory time before/after self-admin0.00.00.2-0.40.20.1-0.1-0.00.10.30.3-0.1-0.0-0.1-0.0-0.0-0.00.10.10.10.1-0.30.3-0.1-0.10.2
Parametrial fat weight0.50.93.4-1.8-1.8-1.51.51.20.8-1.1-1.00.90.90.80.8-0.60.60.50.50.40.4-0.20.20.40.4-0.5
Pavlov. Cond. lever latency0.30.41.1-0.5-0.8-0.90.90.60.6-1.0-1.00.50.50.50.5-0.60.50.60.60.60.6-0.60.6-0.5-0.50.4
Pavlov. Cond. magazine entry latency0.50.61.7-0.4-0.20.3-0.3-0.5-0.70.70.7-0.6-0.6-0.7-0.70.8-0.8-0.9-0.9-0.9-0.90.9-0.91.21.2-1.3
Pavlov. Cond. change in total contacts0.10.10.5-0.7-0.6-0.20.20.30.10.20.20.10.20.10.10.0-0.0-0.1-0.1-0.1-0.10.2-0.20.50.5-0.5
Pavlov. Cond. index score0.00.00.1-0.10.00.1-0.10.20.10.30.30.20.20.10.2-0.10.10.10.00.00.00.0-0.00.10.1-0.1
Pavlov. Cond. latency score0.00.10.3-0.10.10.2-0.3-0.0-0.10.60.6-0.10.0-0.1-0.00.2-0.1-0.2-0.2-0.2-0.20.3-0.30.30.3-0.3
Pavlov. Cond. lever contacts0.10.20.70.30.50.6-0.6-0.2-0.30.80.8-0.2-0.2-0.2-0.20.3-0.2-0.3-0.4-0.3-0.30.4-0.40.30.3-0.3
Pavlov. Cond. magazine entry number0.10.10.20.20.10.1-0.1-0.4-0.3-0.2-0.2-0.3-0.4-0.3-0.40.3-0.4-0.3-0.3-0.3-0.30.2-0.20.20.2-0.2
Pavlov. Cond. intertrial magazine entries0.80.91.2-0.3-0.5-0.90.90.91.0-1.1-1.10.90.81.00.9-1.01.01.01.11.01.0-1.01.0-1.1-1.11.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.20.00.10.2-0.20.0-0.10.40.4-0.00.1-0.00.10.00.0-0.1-0.0-0.1-0.10.2-0.20.10.1-0.1
Pavlov. Cond. response bias0.00.00.1-0.1-0.00.1-0.10.20.10.30.30.10.20.10.2-0.10.10.10.00.00.00.0-0.00.10.1-0.1
Pavlov. Cond. lever latency0.10.10.7-0.2-0.3-0.20.20.30.3-0.8-0.80.30.30.30.3-0.30.30.30.20.30.3-0.30.3-0.3-0.30.3
Pavlov. Cond. magazine entry latency4.55.16.21.71.92.3-2.3-2.4-2.42.52.5-2.4-2.4-2.4-2.42.4-2.3-2.3-2.3-2.3-2.32.2-2.22.02.0-1.9
Pavlov. Cond. change in total contacts0.81.11.80.30.60.8-0.8-1.0-1.11.31.4-1.0-1.1-1.1-1.11.1-1.1-1.1-1.2-1.2-1.21.0-1.01.21.2-1.2
Pavlov. Cond. index score1.41.83.20.91.21.3-1.3-1.3-1.41.81.8-1.4-1.4-1.4-1.41.4-1.3-1.4-1.4-1.4-1.41.2-1.21.21.2-1.2
Pavlov. Cond. latency score1.11.42.70.81.01.1-1.1-1.2-1.21.61.6-1.2-1.2-1.2-1.21.2-1.2-1.2-1.2-1.2-1.21.1-1.11.11.1-1.0
Pavlov. Cond. lever contacts0.00.00.30.30.30.1-0.1-0.00.00.60.50.00.00.00.0-0.10.10.10.10.10.1-0.10.1-0.2-0.20.2
Pavlov. Cond. magazine entry number5.66.98.8-2.0-2.3-2.72.72.72.8-3.0-3.02.82.82.82.8-2.72.72.72.72.62.6-2.62.6-2.3-2.32.2
Pavlov. Cond. intertrial magazine entries1.72.23.9-1.7-1.7-1.71.71.61.5-2.0-1.91.51.51.51.5-1.41.41.41.41.31.3-1.41.4-1.0-1.00.9
Pavlov. Cond. lever-magazine prob. diff.1.92.44.01.11.41.5-1.5-1.6-1.62.02.0-1.6-1.6-1.6-1.61.6-1.5-1.5-1.6-1.5-1.51.4-1.41.31.3-1.3
Pavlov. Cond. response bias0.91.22.50.91.11.1-1.1-1.1-1.11.61.6-1.1-1.1-1.1-1.11.1-1.1-1.1-1.0-1.1-1.11.1-1.10.90.9-0.8
Time in closed arm before self-admin0.10.10.7-0.8-0.3-0.30.30.30.20.40.40.20.10.10.1-0.10.10.1-0.00.00.00.1-0.10.20.2-0.1
Time in closed arm after self-admin0.00.00.20.50.50.2-0.20.00.10.30.30.10.10.10.1-0.20.10.20.10.20.2-0.00.0-0.3-0.30.1
Time in open arm before self-admin0.10.10.50.70.50.4-0.4-0.5-0.4-0.2-0.2-0.3-0.3-0.2-0.30.3-0.2-0.2-0.2-0.2-0.2-0.00.1-0.1-0.10.1
Time in open arm after self-admin0.00.00.10.1-0.0-0.10.10.00.1-0.3-0.30.10.10.10.2-0.10.20.10.20.10.1-0.30.3-0.2-0.20.3
Bone: periosteal estimation0.00.10.3-0.5-0.5-0.50.50.40.2-0.2-0.20.30.30.30.3-0.20.20.20.20.10.1-0.10.10.10.1-0.1
Bone: periosteal perimeter0.10.10.4-0.6-0.5-0.30.30.1-0.10.10.1-0.1-0.0-0.1-0.10.2-0.2-0.3-0.2-0.3-0.30.3-0.30.60.6-0.7
Bone: post-yield work3.54.712.6-1.2-0.80.5-0.6-1.3-2.01.31.3-1.8-1.7-2.0-1.92.3-2.3-2.4-2.5-2.6-2.62.4-2.43.43.4-3.5
Progressive ratio test 1 active lever presses1.21.32.1-1.2-1.5-1.41.41.31.4-1.2-1.21.31.21.21.2-1.11.01.10.91.11.1-0.80.8-0.8-0.80.5
Progressive ratio test 1 breakpoint1.21.32.0-1.0-1.4-1.31.31.31.4-1.2-1.21.31.31.21.2-1.21.11.20.91.11.1-0.80.8-0.9-0.90.6
Progressive ratio test 1 inactive lever presses0.20.20.8-0.4-0.9-0.60.60.60.6-0.4-0.40.60.50.50.5-0.40.30.40.20.40.40.2-0.2-0.2-0.20.1
Progressive ratio test 2 active lever presses1.92.14.3-2.0-2.1-1.91.81.71.7-1.7-1.61.51.51.51.4-1.41.21.31.11.21.2-1.21.2-0.7-0.70.3
Progressive ratio test 2 breakpoint3.23.65.3-2.0-2.3-2.32.32.22.2-2.1-2.12.12.02.02.0-1.91.81.81.71.81.8-1.71.7-1.2-1.20.8
Progressive ratio test 2 inactive lever presses3.54.011.8-3.4-3.2-2.72.72.52.4-1.9-1.82.22.12.02.0-1.81.61.71.31.51.5-1.31.3-0.6-0.60.2
Incentive Sensitization - Responses0.20.20.6-0.7-0.6-0.50.50.40.4-0.6-0.60.30.40.30.4-0.30.20.30.40.20.2-0.40.4-0.1-0.1-0.2
Incentive Sensitization - Breakpoint0.30.30.9-0.9-0.8-0.70.70.60.6-0.8-0.70.50.60.50.6-0.50.40.40.60.40.4-0.60.6-0.2-0.2-0.1
Sum of active levers in priming session hrs 5-61.31.33.50.80.3-0.20.30.71.0-0.9-0.90.91.01.01.1-1.21.21.31.31.31.3-1.21.2-1.7-1.71.9
Progressive ratio5.46.27.80.61.52.1-2.1-2.4-2.72.52.6-2.6-2.6-2.7-2.72.7-2.8-2.7-2.8-2.8-2.82.3-2.32.72.7-2.5
Food seeking constrained by brief footshock0.30.40.70.30.50.7-0.7-0.7-0.60.50.6-0.7-0.8-0.7-0.70.6-0.7-0.6-0.9-0.6-0.60.6-0.60.40.4-0.1
Seeking ratio, punishment vs. effort3.24.04.9-0.5-1.1-1.61.62.02.2-2.0-2.02.12.12.12.1-2.22.22.22.12.22.2-1.71.7-2.2-2.22.2
Retroperitoneal fat weight3.411.120.2-4.5-4.5-4.44.44.03.6-3.7-3.63.63.63.43.4-3.13.03.02.62.82.8-3.03.0-1.5-1.51.1
Reaction time number correct0.10.21.91.40.90.4-0.4-0.3-0.1-0.2-0.3-0.2-0.0-0.00.1-0.10.20.20.40.20.2-0.10.1-0.5-0.50.7
Reaction time mean minus median2.33.15.01.11.81.8-1.8-1.9-1.82.22.2-1.8-1.7-1.8-1.71.8-1.9-1.7-1.7-1.7-1.71.8-1.81.21.2-1.3
Reaction time mean minus median AUC1.11.52.61.21.61.5-1.5-1.5-1.31.51.5-1.3-1.2-1.2-1.21.2-1.2-1.1-1.0-1.1-1.11.1-1.10.50.5-0.5
Reaction time num false alarms0.40.51.20.4-0.1-0.40.40.40.5-0.9-0.90.50.60.60.6-0.70.70.70.70.70.8-0.80.8-1.0-1.01.1
Reaction time num false alarms AUC0.10.11.01.00.70.4-0.3-0.4-0.3-0.3-0.3-0.2-0.2-0.1-0.10.0-0.00.0-0.10.10.1-0.20.2-0.6-0.60.7
Reaction time trials correct on left0.10.21.91.40.90.4-0.4-0.3-0.1-0.2-0.3-0.2-0.0-0.00.1-0.10.20.20.40.20.2-0.10.1-0.5-0.50.7
Reaction time trials on left0.20.22.31.51.00.5-0.5-0.3-0.2-0.2-0.2-0.2-0.0-0.00.0-0.10.20.10.40.20.2-0.10.1-0.5-0.50.8
Reaction time mean0.30.41.7-0.70.40.4-0.4-0.3-0.31.31.3-0.4-0.4-0.4-0.40.5-0.6-0.5-0.7-0.6-0.60.5-0.50.60.6-0.8
Reaction time mean AUC0.30.41.4-0.80.20.3-0.3-0.3-0.31.21.2-0.4-0.3-0.4-0.40.5-0.6-0.5-0.6-0.6-0.60.5-0.50.60.6-0.8
Median of all reaction times0.20.20.9-0.9-0.00.1-0.1-0.0-0.10.80.8-0.2-0.2-0.2-0.30.3-0.4-0.4-0.5-0.4-0.40.3-0.30.60.6-0.8
Reaction time omissions1.21.63.31.81.81.6-1.6-1.5-1.41.51.4-1.4-1.3-1.3-1.21.2-1.2-1.1-0.9-1.0-1.01.3-1.30.50.5-0.4
Reaction time false alarm rate0.10.10.30.20.0-0.10.10.00.1-0.4-0.40.20.10.20.2-0.20.20.20.10.30.3-0.30.3-0.5-0.50.5
Reaction time premature initiation rate1.52.03.71.91.81.9-1.9-1.8-1.61.11.1-1.6-1.6-1.4-1.51.4-1.4-1.3-1.5-1.3-1.31.1-1.10.60.6-0.4
Reaction time premature initiations1.62.38.22.92.52.2-2.2-2.0-1.71.11.1-1.6-1.6-1.4-1.41.3-1.2-1.2-1.2-1.1-1.11.1-1.10.20.20.1
Std. dev. reaction times0.81.12.60.31.01.0-1.0-1.0-1.01.61.6-1.0-0.9-1.0-0.91.0-1.1-1.0-1.1-1.0-1.01.1-1.10.80.8-0.9
Reaction time trials completed0.20.22.31.51.00.5-0.5-0.3-0.2-0.2-0.2-0.2-0.0-0.00.0-0.10.20.10.40.20.2-0.10.1-0.5-0.50.8
Reaction time trials AUC0.10.21.81.30.80.4-0.4-0.3-0.2-0.3-0.3-0.2-0.0-0.00.0-0.10.20.10.40.20.2-0.00.1-0.4-0.40.7
Run reversals in cocaine runway, females2.92.83.50.61.11.6-1.7-1.7-1.81.31.3-1.8-1.8-1.8-1.81.8-1.8-1.8-1.9-1.8-1.81.8-1.81.71.7-1.7
Run reversals in cocaine runway, males0.30.30.90.20.4-0.00.00.20.4-0.2-0.20.30.20.40.3-0.50.50.50.50.60.6-0.80.8-0.9-0.91.0
Latency to leave start box in cocaine runway0.40.51.2-0.6-0.20.2-0.3-0.4-0.60.50.5-0.6-0.4-0.6-0.50.7-0.7-0.8-0.8-0.8-0.80.7-0.71.11.1-1.1
Latency to leave start box in cocaine runway, F0.40.51.0-0.40.10.4-0.4-0.5-0.60.70.8-0.6-0.5-0.7-0.60.7-0.7-0.8-0.8-0.8-0.80.8-0.81.01.0-0.8
Latency to leave start box in cocaine runway, M0.00.00.2-0.1-0.3-0.10.10.0-0.0-0.4-0.40.00.10.00.10.00.0-0.0-0.1-0.0-0.0-0.10.10.10.1-0.2
Std. dev. time between licks in bursts0.30.31.31.00.80.4-0.4-0.10.2-0.2-0.30.10.10.30.2-0.40.40.50.50.50.5-0.40.4-1.0-1.01.1
Total sessions with >9 infusions0.20.20.9-0.9-0.9-0.60.60.60.6-0.3-0.30.40.50.40.4-0.30.20.30.10.20.2-0.10.10.00.0-0.3
Short access day 1 total inactive lever presses1.41.54.4-1.9-2.1-1.71.71.51.5-1.4-1.41.41.31.21.2-1.10.91.10.71.01.0-0.40.4-0.5-0.50.5
Short access day 10 total inactive lever presses0.70.72.9-1.7-1.4-1.11.11.01.0-0.8-0.70.90.90.80.8-0.70.60.70.50.60.6-0.50.5-0.2-0.20.4
Short access day 1 total infusions0.60.64.2-2.1-1.9-1.31.20.90.8-0.7-0.70.60.40.40.3-0.40.20.30.00.20.2-0.10.10.40.4-0.5
Short access day 10 total infusions1.11.24.3-1.6-0.70.0-0.1-0.4-0.50.60.7-0.7-0.8-0.9-0.91.0-1.2-1.1-1.4-1.2-1.21.0-1.01.71.7-2.1
Short access total infusions0.30.31.4-1.2-0.9-0.30.20.1-0.00.10.2-0.2-0.3-0.3-0.40.4-0.5-0.5-0.7-0.5-0.50.5-0.50.90.9-1.2
Short access day 1 locomotion0.30.32.0-1.4-1.3-0.80.70.60.5-0.3-0.30.40.40.30.3-0.20.00.1-0.1-0.0-0.00.2-0.20.50.5-0.8
Short access day 10 total locomotion0.10.10.9-0.9-0.6-0.20.20.30.20.20.20.10.0-0.0-0.00.1-0.2-0.2-0.4-0.2-0.20.5-0.50.50.5-0.8
Short access total locomotion0.20.20.7-0.6-0.6-0.10.10.10.10.40.40.0-0.1-0.1-0.10.2-0.4-0.3-0.6-0.3-0.30.8-0.80.60.6-0.7
One hour access (0.3 mA shock)4.75.411.8-3.4-3.4-3.13.12.82.6-2.7-2.62.42.42.32.2-2.12.02.01.71.91.9-1.91.9-1.0-1.00.6
Compulsive drug intake1.31.36.62.61.91.5-1.5-1.5-1.21.00.9-1.3-1.2-1.1-1.10.9-0.9-0.8-0.7-0.7-0.70.9-0.9-0.0-0.00.3
One hour access (shock baseline)5.66.513.3-3.6-3.5-3.33.33.12.9-2.5-2.52.82.72.72.6-2.42.32.32.02.22.2-2.02.0-1.2-1.20.9
Social response proportion1.41.52.10.91.01.2-1.2-1.3-1.41.21.2-1.3-1.2-1.3-1.21.3-1.3-1.3-1.2-1.3-1.31.4-1.41.11.1-1.1
Social responses0.20.32.21.50.90.8-0.7-0.5-0.50.20.2-0.4-0.3-0.4-0.30.3-0.2-0.2-0.1-0.2-0.20.6-0.6-0.1-0.10.2
Social time0.50.71.81.31.01.0-1.0-0.9-0.90.50.5-0.9-0.9-0.8-0.80.8-0.7-0.7-0.7-0.7-0.71.0-1.00.40.4-0.4
Soleus weight4.312.716.3-3.1-3.5-3.93.94.03.9-3.6-3.63.94.03.93.9-3.73.63.63.53.63.5-3.43.4-2.7-2.72.5
Bone: stiffness2.94.55.60.71.31.8-1.8-2.0-2.22.02.1-2.2-2.2-2.2-2.32.3-2.3-2.3-2.4-2.3-2.32.2-2.22.32.3-2.3
Tibialis anterior weight3.010.140.66.46.44.7-4.6-3.6-2.63.83.7-3.0-3.0-2.6-2.62.0-1.9-1.7-1.6-1.5-1.42.2-2.2-0.6-0.61.1
Time to tail flick, vehicle, before self-admin2.22.33.6-0.60.61.0-1.1-1.4-1.51.51.6-1.4-1.6-1.6-1.71.7-1.7-1.7-1.9-1.7-1.71.0-1.11.81.8-1.9
Time to tail flick, vehicle, after self-admin2.62.84.12.01.71.9-1.9-1.8-1.81.61.6-1.7-1.8-1.7-1.71.7-1.6-1.6-1.5-1.6-1.62.0-2.01.21.2-1.0
Time to tail flick, test, before self-admin1.11.02.2-0.40.10.6-0.6-0.6-0.81.11.1-0.8-0.8-0.9-0.91.0-1.1-1.1-1.3-1.1-1.11.2-1.21.41.4-1.5
Time to tail flick, test, after self-admin0.20.21.5-0.20.60.3-0.3-0.2-0.21.21.2-0.2-0.2-0.2-0.20.1-0.1-0.1-0.0-0.1-0.1-0.10.10.10.10.0
Delta time to tail flick, vehicle, before/after SA0.70.74.92.21.01.1-1.1-0.8-0.80.40.3-0.8-0.6-0.6-0.60.6-0.5-0.5-0.3-0.5-0.51.3-1.30.20.2-0.1
Delta time to tail flick, test, before/after SA0.80.82.70.71.00.00.00.20.50.40.30.50.40.60.5-0.80.90.91.01.01.0-1.11.2-1.4-1.41.6
Tibia length0.20.62.20.80.5-0.10.10.40.60.0-0.00.50.60.70.7-0.80.80.91.00.90.9-0.70.8-1.3-1.31.5
Ambulatory time before self-admin0.20.20.4-0.00.10.3-0.3-0.4-0.60.00.1-0.5-0.5-0.5-0.50.5-0.5-0.6-0.5-0.6-0.60.1-0.10.70.7-0.6
Ambulatory time after self-admin0.30.32.5-1.6-0.7-0.30.30.1-0.10.10.2-0.2-0.0-0.3-0.10.3-0.3-0.4-0.3-0.4-0.4-0.20.10.90.9-0.8
Bone: tissue strength0.00.00.2-0.1-0.4-0.20.20.1-0.1-0.2-0.2-0.00.0-0.0-0.00.1-0.1-0.1-0.1-0.1-0.10.3-0.30.30.3-0.4
Total heroin consumption2.73.27.22.72.32.3-2.2-2.1-1.91.91.9-1.8-1.9-1.8-1.81.6-1.6-1.6-1.5-1.5-1.51.6-1.60.80.8-0.7
Bone: trabecular number2.13.35.6-0.20.51.1-1.2-1.6-1.91.51.6-1.9-1.8-1.9-1.92.0-2.0-2.1-2.1-2.1-2.11.5-1.52.32.3-2.4
Bone: trabecular spacing0.70.91.60.5-0.0-0.50.50.91.0-0.5-0.61.11.01.11.0-1.11.11.11.11.11.1-0.40.4-1.2-1.21.2
Bone: trabecular thickness0.50.62.9-1.7-1.2-0.50.5-0.1-0.4-0.2-0.1-0.4-0.4-0.6-0.50.6-0.7-0.7-0.7-0.8-0.80.0-0.01.31.3-1.4
Bone: trabecular tissue density5.98.310.6-2.4-2.7-3.03.03.33.2-2.9-2.83.23.23.23.2-3.03.03.02.92.92.9-2.72.7-2.3-2.32.1
Water consumed over 24 hours0.91.11.40.80.91.0-1.0-1.1-1.21.01.0-1.2-1.2-1.1-1.21.1-1.1-1.1-1.1-1.1-1.11.0-1.00.90.9-0.9
Number of responses in last shaping day0.50.50.7-0.2-0.8-0.80.80.80.8-0.6-0.60.80.80.80.8-0.80.70.70.60.70.7-0.30.3-0.6-0.60.7