Hub : Traits : Tibialis anterior weight : ← : →

chr11:32,161,467-35,008,541

Trait: Tibialis anterior weight

Best TWAS P=1.61e-09 · Best GWAS P=2.59e-09 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Dyrk1a	alternative TSS	NM_012791.3	0.04	1918	0.02	1.0e-03	-5.78	7.63e-09	0.54	FALSE
Adipose	Ttc3	alternative TSS	XM_039088464.1	0.05	1975	0.05	7.3e-06	-5.45	5.01e-08	0.48	FALSE
Adipose	LOC108352312	gene expression	LOC108352312	0.4	2203	0.25	3.1e-27	-5.36	8.28e-08	0.66	FALSE
Adipose	LOC120095637	gene expression	LOC120095637	0.11	1	0.09	2.8e-10	5.85	5.01e-09	0.82	FALSE
Adipose	Ttc3	gene expression	Ttc3	0.34	1975	0.38	1.4e-44	5.67	1.41e-08	0.59	FALSE
Adipose	Dyrk1a	isoform ratio	XM_039088028.1	0.06	1	0.05	1.6e-06	-5.68	1.34e-08	0.47	FALSE
Adipose	Morc3	isoform ratio	XM_039088415.1	0.03	4	0.01	4.4e-02	-6.03	1.61e-09	0.54	TRUE
Adipose	Ttc3	isoform ratio	XM_039088464.1	0.1	1	0.06	1.1e-07	5.79	7.10e-09	0.65	FALSE
Adipose	Ttc3	isoform ratio	XM_039088465.1	0.07	1	0.04	4.7e-05	-5.74	9.36e-09	0.47	FALSE
Adipose	Cbr1	mRNA stability	Cbr1	0.17	1982	0.13	7.0e-14	5.59	2.30e-08	0.68	FALSE
Adipose	Vps26c	mRNA stability	Vps26c	0.04	1882	0.03	1.9e-04	-5.4	6.70e-08	0.39	TRUE
BLA	Cbr1l1	gene expression	Cbr1l1	0.61	2021	0.44	2.2e-25	5.48	4.37e-08	0.69	FALSE
BLA	LOC120095637	gene expression	LOC120095637	0.16	1706	0.1	8.8e-06	-5.24	1.57e-07	0.66	TRUE
BLA	Setd4	gene expression	Setd4	0.53	1980	0.33	2.3e-18	5.63	1.85e-08	0.68	FALSE
BLA	Setd4	intron excision ratio	chr11_32845874_32847402	0.1	1	0.03	1.6e-02	-5.6	2.13e-08	0.05	FALSE
BLA	Setd4	intron excision ratio	chr11_32845874_32853438	0.13	1	0.06	5.3e-04	5.67	1.45e-08	0.16	FALSE
Brain	Cbr1l1	gene expression	Cbr1l1	0.62	38	0.61	5.8e-71	5.68	1.34e-08	0.69	FALSE
Brain	LOC108352311	gene expression	LOC108352311	0.03	1	0.03	1.3e-03	-5.58	2.47e-08	0.03	FALSE
Brain	LOC120095639	gene expression	LOC120095639	0.02	1	0.01	3.4e-02	5.61	1.98e-08	0.04	FALSE
Brain	Setd4	gene expression	Setd4	0.45	65	0.48	2.5e-50	-5.74	9.33e-09	0.68	FALSE
Brain	Setd4	isoform ratio	NM_001113747.1	0.05	6	0.02	6.9e-03	5.51	3.57e-08	0.36	TRUE
Brain	Setd4	isoform ratio	XR_005490972.1	0.06	1980	0.02	3.4e-03	-5.41	6.47e-08	0.67	FALSE
Brain	Ttc3	isoform ratio	XM_039088473.1	0.03	1	0.03	1.3e-03	5.78	7.67e-09	0.05	FALSE
Brain	Kcnj6	intron excision ratio	chr11_34250394_34308566	0.07	2463	0.03	1.7e-03	5.24	1.59e-07	0.54	FALSE
Brain	Kcnj6	intron excision ratio	chr11_34276411_34308566	0.04	1	0.01	1.8e-02	5.76	8.33e-09	0.09	FALSE
Brain	Setd4	intron excision ratio	chr11_32845874_32847402	0.08	1980	0.04	6.2e-05	5.22	1.76e-07	0.68	FALSE
Brain	Setd4	intron excision ratio	chr11_32847490_32850712	0.06	1	0.08	1.2e-07	-5.68	1.35e-08	0.72	FALSE
Brain	Ttc3	intron excision ratio	chr11_33721965_33734534	0.15	69	0.18	1.1e-16	-5.38	7.51e-08	0.64	FALSE
Eye	Vps26c	mRNA stability	Vps26c	0.6	1883	0.17	1.3e-03	-5.83	5.43e-09	0.43	FALSE
IL	Cbr1l1	alternative polyA	NM_001409216.2	0.4	162	0.31	4.5e-08	-5.91	3.44e-09	0.61	FALSE
IL	Cbr1l1	alternative polyA	XM_039088787.1	0.39	340	0.29	9.3e-08	5.87	4.47e-09	0.48	FALSE
IL	Cbr1l1	gene expression	Cbr1l1	0.52	42	0.36	2.0e-09	5.77	8.16e-09	0.7	FALSE
IL	Cbr1l2	gene expression	Cbr1l2	0.24	48	0.16	9.3e-05	-5.78	7.53e-09	0.66	FALSE
IL	Morc3	gene expression	Morc3	0.18	1	0.07	9.1e-03	-5.53	3.16e-08	0.05	FALSE
IL	Setd4	gene expression	Setd4	0.65	30	0.48	4.7e-13	5.7	1.22e-08	0.69	FALSE
IL	Setd4	intron excision ratio	chr11_32845874_32847402	0.16	1	0.12	6.7e-04	-5.71	1.15e-08	0.06	FALSE
IL	Setd4	intron excision ratio	chr11_32845874_32853438	0.16	1	0.12	7.4e-04	5.53	3.21e-08	0.05	FALSE
IL	Vps26c	mRNA stability	Vps26c	0.21	80	0.09	3.1e-03	5.45	5.10e-08	0.44	FALSE
LHb	Cldn14	gene expression	Cldn14	0.18	55	0.16	1.1e-04	5.89	3.77e-09	0.55	FALSE
LHb	Setd4	gene expression	Setd4	0.4	35	0.37	8.2e-10	5.82	5.84e-09	0.68	FALSE
LHb	Morc3	isoform ratio	XM_039088415.1	0.13	1	0.08	6.2e-03	5.53	3.21e-08	0.05	FALSE
LHb	Vps26c	mRNA stability	Vps26c	0.21	1	0.18	5.6e-05	5.59	2.24e-08	0.06	FALSE
Liver	Cldn14	alternative TSS	NM_001013429.1	0.16	1	0.15	3.7e-16	5.57	2.56e-08	0.5	FALSE
Liver	Cldn14	alternative TSS	XM_006248059.3	0.22	102	0.21	1.9e-22	-5.19	2.14e-07	0.67	FALSE
Liver	Cbr3	gene expression	Cbr3	0.04	1	0.01	7.9e-03	5.68	1.34e-08	0.06	FALSE
Liver	Cldn14	gene expression	Cldn14	0.05	1	0.05	4.9e-06	-5.6	2.13e-08	0.44	FALSE
Liver	Dop1b	gene expression	Dop1b	0.08	1	0.07	1.5e-08	-5.63	1.77e-08	0.67	FALSE
Liver	LOC108352311	gene expression	LOC108352311	0.04	31	0.02	2.6e-03	-5.58	2.36e-08	0.45	FALSE
Liver	Ripply3	gene expression	Ripply3	0.06	1	0.05	2.3e-06	5.76	8.54e-09	0.61	FALSE
Liver	Setd4	gene expression	Setd4	0.3	41	0.3	3.9e-33	-5.8	6.60e-09	0.69	FALSE
Liver	Cldn14	intron excision ratio	chr11_33233296_33241680	0.06	1	0.04	8.2e-06	5.57	2.56e-08	0.26	FALSE
Liver	Cldn14	intron excision ratio	chr11_33233296_33242036	0.17	18	0.12	1.8e-13	5.29	1.24e-07	0.66	FALSE
Liver	Cldn14	mRNA stability	Cldn14	0.51	63	0.46	2.6e-56	5.5	3.77e-08	0.7	FALSE
Liver	Hlcs	mRNA stability	Hlcs	0.08	17	0.09	3.3e-10	5.18	2.19e-07	0.27	FALSE
NAcc	Dyrk1a	alternative TSS	NM_012791.3	0.02	1	0.01	8.3e-03	5.76	8.24e-09	0.06	FALSE
NAcc	Cbr1l1	gene expression	Cbr1l1	0.67	264	0.65	5.2e-99	-5.31	1.07e-07	0.68	FALSE
NAcc	LOC108352311	gene expression	LOC108352311	0.07	4	0.06	2.2e-07	5.35	8.57e-08	0.55	FALSE
NAcc	Ripply3	gene expression	Ripply3	0.04	1	0.05	3.0e-06	5.76	8.24e-09	0.54	FALSE
NAcc	Setd4	gene expression	Setd4	0.37	60	0.35	5.3e-42	-5.47	4.42e-08	0.68	FALSE
NAcc	Setd4	isoform ratio	XM_039087973.1	0.08	1	0.08	7.0e-10	-5.63	1.83e-08	0.67	FALSE
NAcc	Vps26c	isoform ratio	XM_039088477.1	0.02	4	0.03	1.2e-04	5.54	2.98e-08	0.37	FALSE
NAcc	Setd4	intron excision ratio	chr11_32845874_32847402	0.04	1	0.04	3.8e-05	-5.56	2.64e-08	0.39	FALSE
NAcc	Setd4	intron excision ratio	chr11_32847490_32850712	0.05	7	0.04	1.1e-05	5.57	2.57e-08	0.67	FALSE
NAcc	Setd4	intron excision ratio	chr11_32850749_32853438	0.03	1980	0.02	1.4e-03	5.21	1.86e-07	0.6	FALSE
NAcc	Ttc3	intron excision ratio	chr11_33721965_33734534	0.02	59	0.02	2.0e-03	-5.35	8.81e-08	0.46	FALSE
NAcc	Setd4	mRNA stability	Setd4	0.03	1	0.02	8.5e-04	5.51	3.54e-08	0.04	FALSE
OFC	Cbr1l1	alternative polyA	NM_001409216.2	0.25	2021	0.12	1.1e-03	5.3	1.16e-07	0.52	FALSE
OFC	Cbr1l1	alternative polyA	XM_039088787.1	0.28	2021	0.13	6.0e-04	-5.19	2.10e-07	0.49	FALSE
OFC	Cbr1l2	gene expression	Cbr1l2	0.13	1	0.1	2.3e-03	5.69	1.28e-08	0.06	FALSE
OFC	Dop1b	gene expression	Dop1b	0.16	1	0.12	7.8e-04	-5.57	2.52e-08	0.06	FALSE
OFC	Setd4	gene expression	Setd4	0.35	1980	0.25	1.4e-06	5.54	2.96e-08	0.66	FALSE
OFC	Kcnj6	intron excision ratio	chr11_34276411_34308566	0.15	2463	0.1	2.1e-03	-5.63	1.79e-08	0.44	FALSE
PL	Hlcs	gene expression	Hlcs	0.09	25	0.1	3.8e-11	-5.49	4.02e-08	0.26	FALSE
PL	Kcnj6	gene expression	Kcnj6	0.03	1	0.04	9.8e-05	-5.86	4.56e-09	0.41	FALSE
PL	LOC108352311	gene expression	LOC108352311	0.1	1	0.11	2.9e-12	-5.76	8.24e-09	0.61	FALSE
PL	Setd4	gene expression	Setd4	0.29	59	0.35	5.7e-40	-5.54	3.04e-08	0.66	FALSE
PL	Setd4	isoform ratio	XM_039087973.1	0.09	16	0.06	1.3e-07	-5.68	1.35e-08	0.7	FALSE
PL	Setd4	intron excision ratio	chr11_32845874_32847402	0.03	2	0.03	4.2e-04	5.57	2.50e-08	0.63	FALSE
PL	Ttc3	intron excision ratio	chr11_33721965_33734534	0.11	1	0.1	2.1e-11	-5.65	1.60e-08	0.47	FALSE
PL	Ttc3	intron excision ratio	chr11_33727139_33728112	0.02	1	0.02	5.9e-03	5.65	1.60e-08	0.04	FALSE
PL	Dop1b	mRNA stability	Dop1b	0.08	18	0.07	2.8e-08	5.34	9.33e-08	0.7	FALSE
PL	Setd4	mRNA stability	Setd4	0.27	1	0.13	5.5e-14	5.61	2.08e-08	0.64	FALSE
PL	Vps26c	mRNA stability	Vps26c	0.15	1883	0.18	1.0e-19	-5.29	1.23e-07	0.38	FALSE
pVTA	Cbr1l1	gene expression	Cbr1l1	0.68	41	0.59	4.8e-31	5.59	2.26e-08	0.7	FALSE
pVTA	Setd4	gene expression	Setd4	0.2	1	0.2	4.9e-09	-5.52	3.43e-08	0.52	FALSE
pVTA	Cbr1l1	isoform ratio	NM_001409216.2	0.46	25	0.43	5.1e-20	5.41	6.17e-08	0.7	FALSE
pVTA	Cbr1l1	isoform ratio	XM_039088787.1	0.52	23	0.47	1.7e-22	-5.21	1.93e-07	0.7	FALSE
pVTA	Kcnj6	isoform ratio	NM_001393803.1	0.14	2463	0.12	1.0e-05	-5.39	6.87e-08	0.65	FALSE
pVTA	Kcnj6	isoform ratio	NM_013192.3	0.14	2463	0.11	2.4e-05	5.4	6.80e-08	0.66	FALSE
pVTA	Setd4	isoform ratio	XM_039087973.1	0.06	1	0.07	4.9e-04	-5.52	3.43e-08	0.06	FALSE
pVTA	Cbr1	intron excision ratio	chr11_32877739_32878644	0.21	1	0.23	2.2e-10	-5.57	2.56e-08	0.59	FALSE
pVTA	Cbr1l1	intron excision ratio	chr11_32877739_32878644	0.21	1	0.23	2.2e-10	-5.57	2.56e-08	0.59	FALSE
pVTA	Cbr1l2	intron excision ratio	chr11_32877739_32878644	0.2	1	0.23	2.2e-10	-5.57	2.56e-08	0.58	FALSE
pVTA	Setd4	intron excision ratio	chr11_32845874_32847402	0.23	5	0.16	1.7e-07	5.55	2.92e-08	0.58	TRUE
RMTg	Cbr1l1	gene expression	Cbr1l1	0.52	115	0.45	1.4e-13	-5.37	7.71e-08	0.67	FALSE
RMTg	Cbr1l2	gene expression	Cbr1l2	0.36	57	0.29	2.4e-08	-5.78	7.62e-09	0.49	FALSE
RMTg	Cbr1l1	isoform ratio	NM_001409216.2	0.14	1	0.12	5.4e-04	-5.67	1.45e-08	0.09	FALSE
RMTg	Cbr1l1	isoform ratio	XM_039088787.1	0.17	1	0.13	2.9e-04	5.67	1.45e-08	0.1	FALSE
RMTg	Setd4	intron excision ratio	chr11_32845874_32853438	0.12	1	0.09	1.9e-03	5.68	1.32e-08	0.06	FALSE
RMTg	Setd4	mRNA stability	Setd4	0.13	3	0.14	1.7e-04	-5.17	2.28e-07	0.53	FALSE