Hub : Genes

RGD1559600

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS NM_001109153.1 0.11 0.06 2.5e-05 0.03 0.03 0.03 0.03 1.1e-04 5.8e-04 7.3e-04 4.6e-04
2 Liver alternative TSS XM_006230140.4 0.1 0.06 3.3e-05 0.03 0.03 0.02 0.03 1.3e-04 6.8e-04 1.3e-03 6.3e-04
3 Liver intron excision ratio chr1_183405725_183416880 0.44 0.37 1.1e-04 0.02 0.01 0.01 0.02 1.3e-03 1.1e-02 2.7e-02 3.6e-03
4 Liver intron excision ratio chr1_183405725_183418750 0.33 0.38 4.1e-03 0.01 -0 0 0.01 5.7e-02 6.2e-01 3.2e-01 4.9e-02
5 Adipose gene expression RGD1559600 0.23 0.1 0.0e+00 0.15 0.17 0.18 0.16 1.6e-16 2.3e-18 7.5e-20 1.7e-17
6 Adipose alternative polyA NM_001109153.1 0.08 0.05 3.4e-07 0.04 0.04 0.04 0.04 8.4e-06 1.7e-05 1.9e-05 3.5e-05
7 Adipose alternative polyA XM_006230140.4 0.07 0.05 5.9e-07 0.04 0.04 0.04 0.04 1.2e-05 2.7e-05 2.5e-05 4.9e-05
8 Brain gene expression RGD1559600 0.06 0.04 7.7e-03 0.03 0.01 0.02 0.01 2.2e-03 3.8e-02 1.2e-02 1.5e-02
9 Adipose isoform ratio XM_006230140.4 0.03 0.02 5.0e-03 0.01 0 0.02 0.01 1.4e-02 1.2e-01 1.6e-03 6.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.81.52.3-1.41.4-1.4-1.5-1.1-1.11.10.71.0
Area under the delay curve0.00.00.10.2-0.20.20.1-0.10.2-0.20.0-0.3
BMI with tail2.79.514.2-3.23.2-3.2-3.8-3.2-3.13.11.33.0
BMI without tail2.915.321.5-4.64.6-4.6-4.5-3.9-3.73.71.92.6
Body weight1.87.913.2-3.43.4-3.4-3.6-2.6-2.22.22.11.4
Weight adjusted by age0.00.00.20.1-0.10.1-0.40.0-0.10.1-0.00.3
Bone surface0.61.23.1-1.31.3-1.3-1.8-0.4-0.40.41.4-0.0
Bone volume1.12.24.3-1.71.7-1.7-2.1-1.3-1.11.11.30.9
Breakpoint value in progressive ratio session0.71.31.91.2-1.21.21.30.91.4-1.4-0.5-1.1
Number of licking bursts1.75.38.42.5-2.52.52.52.92.1-2.1-1.4-1.6
Context. condit. distance diff. score0.40.51.01.0-1.01.00.60.50.5-0.5-0.2-0.1
Locomotion velocity, session 10.10.10.2-0.20.2-0.2-0.4-0.0-0.00.00.5-0.2
Locomotion distance, session 10.70.91.3-1.11.1-1.1-1.2-0.9-0.90.90.50.7
Locomotion velocity, session 20.00.00.1-0.10.1-0.1-0.00.30.1-0.10.1-0.3
Locomotion distance, session 21.62.23.8-1.81.8-1.8-2.0-1.1-1.41.41.20.3
Locomotion velocity, session 30.50.61.0-0.80.8-0.8-1.0-0.7-0.40.41.00.6
Locomotion distance, session 30.30.31.5-0.30.3-0.3-0.80.00.5-0.51.2-0.4
Stereotopy head waving bouts, day 30.30.40.80.7-0.70.70.90.50.5-0.5-0.80.1
Stereotopy head waving duration, day 30.10.10.40.3-0.30.30.50.20.1-0.1-0.60.3
Locomotion velocity, session 71.41.67.5-0.60.6-0.6-1.90.10.6-0.62.7-1.2
Locomotion distance, session 70.81.01.70.9-0.90.9-0.20.71.1-1.11.3-1.2
Stereotopy head waving bouts, day 70.40.41.1-1.01.0-1.0-0.5-0.3-0.20.20.20.2
Stereotopy head waving duration, day 72.02.44.6-2.12.1-2.1-1.7-1.2-1.11.10.80.8
Locomotion velocity, session 80.10.10.2-0.30.3-0.3-0.30.1-0.20.20.3-0.4
Locomotion distance, session 80.10.20.5-0.20.2-0.2-0.7-0.3-0.50.50.70.1
Degree of sensitization distance0.50.61.60.9-0.90.90.90.1-0.40.4-1.20.5
Degree of sensitization stereotypy1.92.14.3-2.12.1-2.1-1.7-0.9-0.70.71.20.1
Conditioned locomotion0.91.12.30.6-0.60.60.31.31.5-1.50.9-1.5
Cocaine response after cond. corrected0.10.10.30.5-0.50.50.60.3-0.00.0-0.4-0.0
Cocaine response after cond. not corrected0.00.10.1-0.20.2-0.2-0.3-0.0-0.10.10.4-0.2
Cocaine response before conditioning1.51.94.3-1.61.6-1.6-2.1-0.7-0.10.12.0-0.5
Saline control response0.20.31.20.2-0.20.20.80.7-0.10.1-0.9-1.1
Bone: connectivity density0.50.81.6-1.11.1-1.1-1.3-0.4-0.60.60.70.5
Bone: cortical apparent density0.71.21.81.3-1.31.31.31.00.8-0.8-1.1-0.1
Bone: cortical area2.33.76.0-2.52.5-2.5-2.4-1.7-1.31.31.7-0.1
Bone: cortical porosity0.70.81.6-1.31.3-1.3-1.1-0.3-0.20.20.9-0.2
Bone: cortical porosity0.30.30.5-0.70.7-0.7-0.60.10.2-0.20.7-0.5
Bone: cortical thickness1.01.62.6-1.61.6-1.6-1.5-1.4-1.01.00.70.5
Bone: cortical thickness0.70.81.5-0.80.8-0.8-0.7-1.2-0.90.9-0.11.2
Bone: cortical tissue density0.71.21.81.3-1.31.31.31.00.8-0.8-1.1-0.1
Condit. Reinf. active minus inactive responses0.10.10.30.3-0.30.30.50.20.1-0.1-0.6-0.4
Condit. Reinf. active-inactive response ratio0.00.00.30.1-0.10.10.00.10.2-0.2-0.1-0.5
Condit. Reinf. active responses0.20.30.90.5-0.50.50.6-0.1-0.40.4-1.00.2
Condit. Reinf. inactive responses0.30.40.80.4-0.40.40.4-0.3-0.80.8-0.90.9
Incentive salience index mean0.00.10.3-0.00.0-0.0-0.10.20.2-0.20.2-0.6
Condit. Reinf. lever presses0.10.10.40.1-0.10.1-0.10.70.4-0.40.4-0.5
Condit. Reinf. active minus inactive responses1.21.84.6-0.40.4-0.4-0.2-1.9-1.71.7-1.12.1
Condit. Reinf. active-inactive response ratio0.91.43.50.2-0.20.20.5-1.2-1.41.4-1.81.9
Condit. Reinf. active responses0.60.91.9-0.50.5-0.5-0.5-1.4-1.31.3-0.41.3
Condit. Reinf. inactive responses0.81.13.6-1.11.1-1.1-1.5-0.10.1-0.11.9-0.7
Condit. Reinf. lever presses1.01.52.3-1.51.5-1.5-1.2-1.1-1.31.30.40.6
Condit. Reinf. lever reinforcers received0.30.41.0-0.30.3-0.3-0.1-1.0-1.01.0-0.50.8
Conditioned reinforcement - actives0.20.61.6-1.11.1-1.1-0.3-0.1-0.20.20.3-1.3
Conditioned reinforcement - inactives0.10.42.2-0.10.1-0.10.9-0.1-0.10.1-0.4-1.5
Conditioned locomotion0.10.10.9-0.20.2-0.20.10.10.2-0.20.1-0.9
Patch foraging indifference point 0 sec0.31.01.6-1.21.2-1.2-0.2-0.7-1.31.3-0.3-0.6
Patch foraging indifference point AUC0.61.42.9-0.70.7-0.7-0.5-1.7-1.51.5-0.71.7
Delay disc. indifference point, 0s delay0.91.11.9-1.31.3-1.3-1.4-1.0-0.30.31.3-0.0
Delay disc. indifference point, 16s delay2.02.85.41.9-1.91.92.31.41.4-1.4-1.5-1.0
Delay disc. indifference point, 2s delay3.03.36.5-2.12.1-2.1-2.6-1.7-1.41.41.70.7
Delay disc. indifference point, 24s delay1.42.23.81.6-1.61.61.91.21.4-1.4-1.2-1.3
Delay disc. indifference point, 4s delay0.20.30.6-0.30.3-0.3-0.4-0.6-0.70.70.00.8
Delay disc. indifference point, 8s delay0.20.30.6-0.50.5-0.5-0.5-0.30.3-0.30.8-0.7
Indifference point function ln k0.20.61.2-1.11.1-1.1-0.6-0.2-0.20.20.8-0.7
Indifference point function log k0.20.61.2-1.11.1-1.1-0.6-0.2-0.20.20.8-0.7
Patch foraging total patch changes 0 sec0.51.32.4-1.41.4-1.4-0.2-1.0-1.51.5-0.4-0.4
Patch foraging total patch changes 12 sec0.20.30.7-0.50.5-0.5-0.2-0.6-0.80.8-0.20.1
Patch foraging total patch changes 18 sec0.10.30.6-0.20.2-0.20.3-0.5-0.70.7-0.80.7
Patch foraging total patch changes 24 sec0.31.01.9-0.80.8-0.8-0.6-1.4-1.31.3-0.41.3
Patch foraging total patch changes 6 sec1.01.75.5-0.20.2-0.21.0-1.1-1.71.7-2.31.4
Patch foraging time to switch 0 sec1.34.88.52.2-2.22.21.32.92.8-2.80.6-1.6
Patch foraging water rate 0 sec0.10.40.8-0.90.9-0.9-0.4-0.5-0.70.70.3-0.2
Patch foraging water rate 12 sec0.31.22.0-1.31.3-1.3-0.9-1.1-1.41.40.1-0.1
Patch foraging water rate 18 sec0.10.30.5-0.60.6-0.6-0.5-0.5-0.70.70.4-0.1
Patch foraging water rate 24 sec0.20.40.6-0.80.8-0.8-0.6-0.5-0.60.60.3-0.3
Patch foraging water rate 6 sec0.50.71.5-0.40.4-0.40.4-0.9-1.21.2-1.11.0
Seeking ratio, delayed vs. immediate footshock0.00.00.10.1-0.10.1-0.30.4-0.20.20.10.3
Distance traveled before self-admin0.10.20.8-0.20.2-0.2-0.40.3-0.90.90.20.2
Distance traveled after self-admin0.61.13.4-0.80.8-0.8-1.9-0.2-0.80.81.41.2
Extensor digitorum longus weight3.313.128.2-4.64.6-4.6-5.3-2.1-0.70.74.70.1
Bone: elastic displacement0.30.41.10.7-0.70.70.8-0.3-0.30.3-1.00.5
Bone: elastic work0.40.61.2-0.60.6-0.6-0.7-1.1-0.80.80.30.8
Bone: endosteal estimation0.92.34.2-1.81.8-1.8-2.1-1.3-1.01.01.9-0.0
Bone: endosteal perimeter0.61.43.4-1.31.3-1.3-1.6-0.4-0.40.41.8-1.0
Epididymis fat weight0.73.34.8-1.81.8-1.8-1.7-2.1-2.22.20.22.0
Delta time in closed arm before/after self-admin0.80.82.10.1-0.10.1-0.60.41.4-1.41.4-0.5
Delta time in open arm before/after self-admin1.72.03.5-1.51.5-1.5-1.0-1.8-1.91.9-0.20.6
Diff in mean of infusions in LGA sessions0.91.63.40.3-0.30.30.8-1.4-1.61.6-1.81.6
Delay discount exponential model param0.10.10.2-0.30.3-0.3-0.2-0.1-0.40.40.00.4
Extinction: sum of active levers before priming0.40.61.01.0-1.01.00.90.40.6-0.6-0.5-0.2
Active lever presses in extinction session 60.10.10.7-0.40.4-0.4-0.0-0.2-0.20.20.1-0.8
Bone: final force4.06.59.5-3.13.1-3.1-3.0-2.7-2.12.11.90.9
Bone: final moment3.65.88.3-2.92.9-2.9-2.8-2.7-2.12.11.61.0
Food consumed during 24 hour testing period1.22.53.8-1.91.9-1.9-1.6-1.8-1.61.60.60.0
Glucose0.00.10.20.0-0.00.00.1-0.2-0.30.3-0.30.5
Heart weight0.20.30.7-0.40.4-0.4-0.1-0.8-0.80.8-0.1-0.1
Delay discount hyperbolic model param0.00.00.0-0.00.0-0.00.20.2-0.10.1-0.10.1
Intermittent access intake day 1-15 change0.10.40.80.9-0.90.90.60.30.4-0.4-0.20.3
Intermittent access intake escalation0.10.40.80.9-0.90.90.70.40.5-0.5-0.30.1
Intermittent access intake escalation 20.50.81.71.3-1.31.30.80.70.7-0.7-0.20.0
Intermitt. access day 1 inactive lever presses0.00.41.00.6-0.60.61.00.10.4-0.4-0.8-0.3
Intermitt. access day 15 inactive lever presses0.20.91.7-1.31.3-1.3-0.7-1.0-0.40.40.9-0.8
Intermitt. access escalation Index0.41.22.4-0.70.7-0.7-0.2-1.4-1.51.5-0.31.5
Intermittent access day 1 total infusions0.30.81.5-1.21.2-1.2-1.0-0.5-0.60.60.7-0.1
Intermittent access day 15 total infusions0.00.00.1-0.20.2-0.2-0.1-0.1-0.30.30.10.1
Intermittent access terminal intake (last 3 days)0.20.30.5-0.60.6-0.6-0.4-0.5-0.70.70.10.4
Intermittent access total infusions1.31.62.8-1.71.7-1.7-1.3-1.1-1.11.10.60.4
Intermittent access day 1 locomotion0.20.40.7-0.60.6-0.6-0.3-0.8-0.80.80.20.2
Intermittent access day 15 total locomotion0.20.61.4-0.40.4-0.40.4-0.8-1.21.2-1.10.4
Intermittent access total locomotion0.91.12.1-1.01.0-1.0-0.3-1.3-1.51.5-0.50.9
Intermittent access standard deviation0.31.42.2-1.01.0-1.0-1.4-1.5-1.11.10.91.5
Left kidney weight1.18.913.0-3.43.4-3.4-3.6-2.9-2.72.72.61.0
Right kidney weight1.510.714.0-3.63.6-3.6-3.7-3.6-3.23.22.32.3
Cocaine induced anxiety0.30.93.20.9-0.90.90.50.1-0.40.4-1.21.8
Post-drug Anxiety1.41.65.51.2-1.21.20.9-0.2-0.80.8-1.72.3
Baseline Anxiety0.10.20.4-0.50.5-0.5-0.3-0.6-0.70.70.20.0
Tail length0.42.34.5-2.12.1-2.1-1.6-1.1-0.90.91.4-0.3
Length with tail0.20.72.4-0.60.6-0.6-0.70.30.7-0.71.6-1.2
Length without tail0.42.23.51.6-1.61.60.91.61.9-1.90.6-1.2
Times rat made contact with spout1.31.52.9-1.61.6-1.6-1.6-0.8-0.30.31.7-0.6
Lifetime Intake1.72.13.7-1.91.9-1.9-1.5-1.2-1.11.10.90.3
Liver weight, left0.40.60.90.9-0.90.90.91.00.7-0.7-0.4-0.6
Liver weight, right0.71.23.20.9-0.90.90.51.11.8-1.80.6-0.5
Locomotor activity0.00.00.10.1-0.10.10.2-0.10.3-0.3-0.0-0.3
Locomotor testing distance0.10.20.5-0.40.4-0.4-0.1-0.7-0.40.4-0.30.3
Locomotor testing rearing0.10.30.50.7-0.70.70.60.30.3-0.3-0.4-0.6
Locomotion in novel chamber0.81.13.3-0.20.2-0.2-0.3-0.7-1.81.8-0.81.4
Locomotion in novel chamber post-restriction0.82.55.61.4-1.41.41.3-0.3-1.31.3-2.42.3
Fecal boli incidents, locomotor time 10.30.72.10.6-0.60.60.31.51.3-1.30.0-0.2
Change in fecal boli incidents, locomotor task0.90.92.1-0.80.8-0.8-0.3-1.4-1.41.4-0.00.3
Time >=10cm from walls, locomotor time 10.70.91.7-1.31.3-1.3-1.0-1.0-0.60.60.80.3
Bouts of movement, locomotor time 12.32.95.22.2-2.22.22.31.20.7-0.7-2.0-0.6
Total resting periods, locomotor time 13.03.55.52.3-2.32.32.31.61.3-1.3-1.8-1.0
Rest time, locomotor task time 11.62.55.51.2-1.21.20.71.82.3-2.30.4-1.7
Distance moved, locomotor task time 10.82.24.2-1.31.3-1.3-0.7-2.0-2.12.1-0.21.5
Vertical activity count, locomotor time 10.64.18.1-1.71.7-1.7-1.2-2.4-2.82.8-0.32.1
Time >=10cm from walls, locomotor time 20.92.54.7-2.22.2-2.2-1.8-1.0-0.50.51.7-0.8
Bouts of movement, locomotor time 20.10.41.4-0.40.4-0.4-0.60.20.7-0.71.2-0.3
Total resting periods, locomotor time 20.10.62.1-0.60.6-0.6-0.90.10.7-0.71.4-0.3
Rest time, locomotor task time 20.10.21.3-0.30.3-0.3-0.40.10.0-0.00.2-1.2
Distance moved, locomotor task time 20.30.41.0-0.70.7-0.7-0.4-1.0-0.60.60.50.7
Vertical activity count, locomotor time 20.30.71.6-0.60.6-0.6-0.2-1.0-1.21.2-0.31.2
Light reinforcement 10.00.10.40.4-0.40.40.50.3-0.20.2-0.6-0.2
Light reinforcement 20.10.10.4-0.30.3-0.30.3-0.0-0.40.4-0.4-0.6
Bone: marrow area0.82.03.7-1.61.6-1.6-1.9-1.3-0.90.91.80.0
Bone: maximum diameter1.53.15.1-2.22.2-2.2-2.3-1.4-1.31.31.5-0.3
Bone: maximum force2.95.78.8-3.03.0-3.0-2.9-2.4-1.91.91.90.7
Bone: maximum moment2.64.97.5-2.72.7-2.7-2.6-2.3-1.81.81.60.7
Mean time between licks in bursts0.00.20.50.4-0.40.40.7-0.10.4-0.4-0.70.1
Mean num. licks in bursts2.87.610.5-3.23.2-3.2-3.2-3.2-2.22.22.21.3
Cd content in liver1.31.44.61.2-1.21.21.50.2-1.01.0-2.10.5
Co content in liver0.50.61.7-0.20.2-0.20.3-0.7-1.31.3-0.90.1
Cu content in liver1.21.52.6-1.11.1-1.1-0.8-1.4-1.61.6-0.11.2
Fe content in liver0.50.61.60.5-0.50.50.7-0.5-0.90.9-1.30.8
K content in liver0.30.30.8-0.60.6-0.6-0.3-0.3-0.90.9-0.2-0.1
Mg content in liver0.10.10.5-0.30.3-0.3-0.20.4-0.00.00.3-0.7
Mn content in liver0.40.51.0-1.01.0-1.0-0.8-0.4-0.10.10.7-0.2
Na content in liver3.13.56.3-2.42.4-2.4-2.5-1.2-0.40.42.40.2
Rb content in liver2.12.49.21.1-1.11.12.0-0.4-1.41.4-3.00.7
Se content in liver0.20.30.5-0.50.5-0.5-0.6-0.5-0.50.50.40.7
Sr content in liver0.60.51.0-1.01.0-1.0-0.8-0.3-0.30.30.7-0.2
Zn content in liver0.91.01.7-1.31.3-1.3-1.3-0.6-0.90.90.9-0.2
Bone: minimum diameter1.52.94.9-2.12.1-2.1-2.2-1.3-0.90.92.1-0.8
Time in familiar zone, hab. session 10.70.82.60.6-0.60.60.9-0.4-0.70.7-1.61.1
Time in novel zone, hab. session 11.82.17.1-0.80.8-0.8-1.30.91.2-1.22.7-2.0
Total zone transitions, hab. session 12.94.05.5-2.42.4-2.4-2.2-1.9-2.22.20.71.0
Total locomotion distance, hab. session 15.17.39.7-3.13.1-3.1-2.9-2.8-2.92.91.31.5
Locomotion velocity, hab. session 14.36.28.4-2.72.7-2.7-2.4-2.7-2.92.90.71.9
Time in familiar zone, hab. session 20.40.41.3-0.40.4-0.4-0.5-1.1-0.60.60.01.1
Time in novel zone, hab. session 20.00.00.2-0.00.0-0.00.10.5-0.00.0-0.1-0.4
Total zone transitions, hab. session 22.63.35.0-2.22.2-2.2-1.9-1.8-1.91.90.70.9
Total locomotion distance, hab. session 23.24.25.5-2.42.4-2.4-2.2-2.2-2.12.10.81.4
Locomotion velocity, hab. session 23.75.06.7-2.62.6-2.6-2.4-2.3-2.32.31.01.4
Novel to familiar place preference ratio0.50.62.10.7-0.70.71.30.2-0.20.2-1.50.3
Novelty place preference0.40.51.70.7-0.70.71.20.4-0.10.1-1.30.2
Time in novel zone, NPP test0.50.62.00.7-0.70.71.20.2-0.30.3-1.40.4
Total zone transitions, NPP test1.62.33.8-2.02.0-2.0-1.8-1.3-1.41.40.70.4
Total locomotion distance, NPP test1.72.33.2-1.51.5-1.5-1.5-1.8-1.71.70.41.5
Locomotion velocity, NPP test1.31.92.5-1.41.4-1.4-1.5-1.6-1.41.40.51.3
Intraocular pressure0.10.10.4-0.10.1-0.1-0.60.10.4-0.40.7-0.1
Delta distance traveled before/after self-admin0.50.61.4-0.90.9-0.9-1.2-0.30.1-0.11.1-0.1
Delta ambulatory time before/after self-admin0.50.82.1-1.01.0-1.0-1.5-0.4-0.00.01.5-0.2
Parametrial fat weight4.09.414.9-3.23.2-3.2-2.4-3.5-3.93.90.22.3
Pavlov. Cond. lever latency0.70.92.20.2-0.20.20.6-1.5-1.21.2-1.31.1
Pavlov. Cond. magazine entry latency1.21.54.1-1.41.4-1.4-1.80.20.2-0.22.0-0.5
Pavlov. Cond. change in total contacts1.71.84.1-0.20.2-0.2-0.91.61.7-1.72.0-1.7
Pavlov. Cond. index score0.91.12.9-0.60.6-0.6-1.01.31.1-1.11.7-1.0
Pavlov. Cond. latency score0.70.92.2-0.70.7-0.7-1.01.10.8-0.81.5-0.9
Pavlov. Cond. lever contacts1.01.23.6-0.80.8-0.8-1.21.00.9-0.91.9-1.0
Pavlov. Cond. magazine entry number1.01.23.70.7-0.70.71.2-0.9-1.11.1-1.91.1
Pavlov. Cond. intertrial magazine entries1.11.44.11.1-1.11.11.4-0.8-0.70.7-2.01.2
Pavlov. Cond. lever-magazine prob. diff.0.81.03.1-0.70.7-0.7-1.21.10.9-0.91.8-0.8
Pavlov. Cond. response bias1.41.85.4-0.70.7-0.7-1.31.31.5-1.52.3-1.3
Pavlov. Cond. lever latency0.91.32.31.5-1.51.51.00.91.1-1.1-0.6-0.4
Pavlov. Cond. magazine entry latency1.11.53.40.9-0.90.91.01.51.8-1.80.3-1.2
Pavlov. Cond. change in total contacts0.30.71.2-0.30.3-0.30.5-1.0-1.11.1-1.11.0
Pavlov. Cond. index score0.00.00.1-0.30.3-0.30.20.10.1-0.1-0.0-0.2
Pavlov. Cond. latency score0.00.10.1-0.30.3-0.30.10.20.2-0.20.2-0.3
Pavlov. Cond. lever contacts0.71.12.1-1.41.4-1.4-0.9-0.8-0.90.90.70.4
Pavlov. Cond. magazine entry number1.41.83.0-1.31.3-1.3-1.7-1.3-1.51.50.80.9
Pavlov. Cond. intertrial magazine entries1.12.54.1-1.71.7-1.7-2.0-1.5-1.71.71.00.8
Pavlov. Cond. lever-magazine prob. diff.0.00.10.2-0.10.1-0.10.40.30.3-0.30.1-0.4
Pavlov. Cond. response bias0.10.10.3-0.50.5-0.50.1-0.2-0.30.3-0.00.2
Time in closed arm before self-admin0.20.40.8-0.70.7-0.7-0.3-0.4-0.90.9-0.30.1
Time in closed arm after self-admin0.30.30.60.7-0.70.70.50.30.3-0.3-0.30.8
Time in open arm before self-admin1.41.73.11.8-1.81.81.11.31.2-1.2-0.4-0.2
Time in open arm after self-admin1.01.11.8-1.31.3-1.3-1.3-0.8-1.01.00.9-0.3
Bone: periosteal estimation2.25.19.0-2.82.8-2.8-3.0-1.9-1.51.52.50.0
Bone: periosteal perimeter1.22.44.0-1.91.9-1.9-2.0-1.1-1.21.21.6-0.5
Bone: post-yield work1.73.05.4-2.32.3-2.3-1.8-1.2-1.61.61.0-0.4
Progressive ratio test 1 active lever presses0.20.40.9-0.60.6-0.6-0.7-0.6-0.40.40.41.0
Progressive ratio test 1 breakpoint0.20.30.9-0.50.5-0.5-0.6-0.5-0.20.20.40.9
Progressive ratio test 1 inactive lever presses0.10.10.4-0.60.6-0.60.1-0.4-0.10.1-0.2-0.2
Progressive ratio test 2 active lever presses0.20.30.8-0.50.5-0.5-0.10.50.5-0.50.4-0.9
Progressive ratio test 2 breakpoint0.20.30.9-0.40.4-0.4-0.10.60.5-0.50.4-0.9
Progressive ratio test 2 inactive lever presses0.10.41.0-1.01.0-1.0-0.5-0.4-0.20.20.6-0.3
Incentive Sensitization - Responses0.51.46.4-0.80.8-0.8-0.11.01.1-1.10.8-2.5
Incentive Sensitization - Breakpoint0.61.46.7-0.90.9-0.9-0.10.90.9-0.90.7-2.6
Sum of active levers in priming session hrs 5-60.80.71.21.1-1.11.11.00.60.7-0.7-0.6-0.2
Progressive ratio0.10.30.9-0.40.4-0.40.1-0.5-0.50.5-0.60.9
Food seeking constrained by brief footshock0.81.02.01.0-1.01.01.41.00.8-0.8-1.0-1.1
Seeking ratio, punishment vs. effort0.30.62.60.1-0.10.1-0.20.60.8-0.81.0-1.6
Retroperitoneal fat weight1.56.712.6-1.91.9-1.9-1.7-3.3-3.53.5-0.83.1
Reaction time number correct0.31.22.11.4-1.41.41.01.11.1-1.1-0.4-0.6
Reaction time mean minus median0.10.51.2-0.70.7-0.7-0.2-0.8-1.11.1-0.40.4
Reaction time mean minus median AUC0.10.61.2-0.60.6-0.60.4-0.6-1.11.1-1.00.1
Reaction time num false alarms0.40.71.41.1-1.11.11.20.20.3-0.3-0.8-0.2
Reaction time num false alarms AUC0.20.50.91.0-1.01.00.90.20.4-0.4-0.4-0.6
Reaction time trials correct on left0.31.22.11.4-1.41.41.01.11.1-1.1-0.4-0.6
Reaction time trials on left0.41.22.11.4-1.41.41.01.01.0-1.0-0.4-0.6
Reaction time mean0.20.40.8-0.40.4-0.4-0.3-0.8-0.90.9-0.30.7
Reaction time mean AUC0.00.10.2-0.20.2-0.2-0.1-0.3-0.40.4-0.10.1
Median of all reaction times0.10.20.5-0.30.3-0.3-0.4-0.6-0.60.6-0.10.7
Reaction time omissions0.20.31.50.2-0.20.20.40.70.4-0.40.2-1.2
Reaction time false alarm rate0.00.00.10.1-0.10.10.3-0.20.1-0.1-0.0-0.4
Reaction time premature initiation rate0.71.23.8-1.01.0-1.0-1.6-0.20.3-0.32.0-0.9
Reaction time premature initiations0.31.03.1-0.10.1-0.1-0.90.61.0-1.01.8-1.5
Std. dev. reaction times0.20.61.1-0.80.8-0.8-0.3-0.8-1.11.1-0.30.5
Reaction time trials completed0.41.22.11.4-1.41.41.01.01.0-1.0-0.4-0.6
Reaction time trials AUC0.30.91.61.3-1.31.30.80.80.9-0.9-0.2-0.4
Run reversals in cocaine runway, females2.63.07.1-2.02.0-2.0-2.7-1.2-0.80.82.10.8
Run reversals in cocaine runway, males0.30.30.80.2-0.20.20.90.20.6-0.6-0.3-0.9
Latency to leave start box in cocaine runway0.20.30.7-0.20.2-0.20.4-0.7-0.80.8-0.70.3
Latency to leave start box in cocaine runway, F0.10.10.20.4-0.40.40.40.40.3-0.30.1-0.3
Latency to leave start box in cocaine runway, M1.11.02.1-0.70.7-0.70.0-1.4-1.51.5-1.20.7
Std. dev. time between licks in bursts0.10.20.5-0.10.1-0.10.1-0.5-0.50.5-0.50.7
Total sessions with >9 infusions4.45.59.1-3.03.0-3.0-2.9-1.9-1.51.52.30.5
Short access day 1 total inactive lever presses0.61.32.3-1.51.5-1.5-0.9-0.60.1-0.11.1-1.4
Short access day 10 total inactive lever presses0.21.42.80.8-0.80.81.20.81.7-1.7-0.4-1.7
Short access day 1 total infusions0.71.53.4-1.51.5-1.5-1.6-0.70.3-0.31.8-0.1
Short access day 10 total infusions2.03.36.1-2.52.5-2.5-2.2-1.0-0.70.72.0-0.5
Short access total infusions2.94.27.5-2.72.7-2.7-2.4-1.7-1.21.21.80.3
Short access day 1 locomotion0.40.71.8-1.01.0-1.0-0.9-0.60.0-0.01.3-0.4
Short access day 10 total locomotion0.83.15.6-1.81.8-1.8-1.8-2.4-1.71.71.11.4
Short access total locomotion2.94.36.4-2.32.3-2.3-2.0-2.5-2.22.21.01.2
One hour access (0.3 mA shock)0.30.30.6-0.40.4-0.4-0.0-0.7-0.80.8-0.60.6
Compulsive drug intake0.10.20.80.2-0.20.20.60.20.1-0.1-0.7-0.9
One hour access (shock baseline)0.10.31.20.1-0.10.10.2-0.5-0.80.8-0.41.1
Social response proportion0.30.30.8-0.20.2-0.20.5-0.8-0.80.8-0.90.1
Social responses0.40.51.70.6-0.60.61.30.20.0-0.0-1.0-0.8
Social time0.50.71.80.5-0.50.51.30.60.5-0.5-1.1-1.3
Soleus weight2.36.89.5-3.13.1-3.1-2.9-2.6-2.62.61.31.4
Bone: stiffness2.34.16.5-2.62.6-2.6-2.4-2.0-1.61.61.50.4
Tibialis anterior weight5.418.531.0-5.45.4-5.4-5.6-3.6-3.23.23.41.4
Time to tail flick, vehicle, before self-admin0.20.20.6-0.50.5-0.5-0.2-0.7-0.50.5-0.60.2
Time to tail flick, vehicle, after self-admin1.02.02.61.4-1.41.41.61.61.6-1.6-0.4-1.4
Time to tail flick, test, before self-admin0.60.74.1-0.80.8-0.80.10.00.1-0.1-0.2-2.0
Time to tail flick, test, after self-admin0.50.51.10.4-0.40.4-0.10.90.9-0.90.9-1.1
Delta time to tail flick, vehicle, before/after SA0.20.20.40.5-0.50.50.40.60.4-0.40.5-0.1
Delta time to tail flick, test, before/after SA0.20.21.00.0-0.00.0-0.7-0.1-0.10.10.71.0
Tibia length0.10.20.5-0.10.1-0.10.1-0.7-0.70.7-0.70.3
Ambulatory time before self-admin0.10.20.60.2-0.20.2-0.00.4-0.80.8-0.30.5
Ambulatory time after self-admin0.60.93.1-0.70.7-0.7-1.8-0.0-0.70.71.40.9
Bone: tissue strength0.10.10.5-0.30.3-0.3-0.4-0.20.2-0.20.7-0.3
Total heroin consumption0.30.40.70.8-0.80.80.70.30.6-0.6-0.30.2
Bone: trabecular number0.61.21.7-1.21.2-1.2-1.3-0.9-1.11.10.51.0
Bone: trabecular spacing0.81.21.81.0-1.01.01.21.21.4-1.4-0.1-1.0
Bone: trabecular thickness3.04.28.8-1.61.6-1.6-1.4-2.8-2.42.4-0.53.0
Bone: trabecular tissue density0.00.10.2-0.00.0-0.00.0-0.3-0.10.1-0.50.4
Water consumed over 24 hours1.22.27.40.4-0.40.40.11.91.8-1.81.3-2.7
Number of responses in last shaping day0.40.51.7-0.00.0-0.0-0.50.21.1-1.11.3-0.0