Hub : Genes

RGD1559600

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS NM_001109153.1 0.11 0.06 2.5e-05 0.03 0.03 0.03 0.03 1.1e-04 5.8e-04 7.7e-04 4.5e-04
2 Liver alternative TSS XM_006230140.4 0.1 0.06 3.3e-05 0.03 0.03 0.02 0.03 1.3e-04 6.8e-04 1.3e-03 6.1e-04
3 Liver intron excision ratio chr1_183405725_183416880 0.44 0.37 1.1e-04 0.02 0.01 0.01 0.02 1.3e-03 1.1e-02 2.6e-02 3.9e-03
4 Liver intron excision ratio chr1_183405725_183418750 0.33 0.38 4.1e-03 0.01 -0 0 0.01 5.7e-02 6.2e-01 3.4e-01 5.0e-02
5 Adipose gene expression RGD1559600 0.23 0.1 0.0e+00 0.15 0.17 0.18 0.16 1.6e-16 2.3e-18 9.2e-20 1.5e-17
6 Adipose alternative polyA NM_001109153.1 0.08 0.05 3.4e-07 0.04 0.04 0.04 0.04 8.4e-06 1.7e-05 1.8e-05 3.4e-05
7 Adipose alternative polyA XM_006230140.4 0.07 0.05 5.9e-07 0.04 0.04 0.04 0.04 1.2e-05 2.7e-05 2.7e-05 5.0e-05
8 Brain gene expression RGD1559600 0.06 0.04 7.7e-03 0.03 0.01 0.01 0.02 2.2e-03 3.8e-02 1.3e-02 1.1e-02
9 Adipose isoform ratio XM_006230140.4 0.03 0.02 5.0e-03 0.01 0 0.02 0 1.4e-02 1.2e-01 1.8e-03 7.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.81.42.31.4-1.41.4-1.51.11.1-1.1-0.7-0.8
Area under the delay curve0.00.00.2-0.20.2-0.20.10.1-0.20.2-0.00.4
BMI with tail2.79.314.13.2-3.23.2-3.83.23.1-3.1-1.3-2.7
BMI without tail4.914.921.54.6-4.64.6-4.53.83.7-3.7-1.9-1.8
Body weight1.87.713.23.4-3.43.4-3.62.52.2-2.2-2.1-0.9
Weight adjusted by age0.00.00.2-0.10.1-0.1-0.40.00.1-0.10.0-0.3
Bone surface0.71.23.11.3-1.31.3-1.80.40.4-0.4-1.40.3
Bone volume1.22.24.31.7-1.71.7-2.11.21.1-1.1-1.3-0.7
Breakpoint value in progressive ratio session1.11.31.9-1.21.2-1.21.3-1.0-1.41.40.50.9
Number of licking bursts3.25.28.2-2.52.5-2.52.5-2.9-2.12.11.41.3
Context. condit. distance diff. score0.40.51.0-1.01.0-1.00.6-0.5-0.50.50.2-0.1
Locomotion velocity, session 10.10.10.20.2-0.20.2-0.5-0.00.0-0.0-0.50.2
Locomotion distance, session 10.70.91.31.1-1.11.1-1.20.90.9-0.9-0.5-0.6
Locomotion velocity, session 20.00.00.10.1-0.10.1-0.0-0.4-0.10.1-0.10.3
Locomotion distance, session 21.62.23.81.8-1.81.8-2.01.01.4-1.4-1.20.0
Locomotion velocity, session 30.50.61.00.8-0.80.8-1.00.70.4-0.4-1.0-0.7
Locomotion distance, session 30.30.31.50.3-0.30.3-0.8-0.1-0.50.5-1.20.2
Stereotopy head waving bouts, day 30.30.40.8-0.70.7-0.70.9-0.5-0.50.50.8-0.3
Stereotopy head waving duration, day 30.10.10.4-0.30.3-0.30.5-0.2-0.10.10.6-0.3
Locomotion velocity, session 71.51.67.50.6-0.60.6-2.0-0.1-0.60.6-2.71.3
Locomotion distance, session 70.70.91.7-0.90.9-0.9-0.2-0.7-1.11.1-1.31.1
Stereotopy head waving bouts, day 70.40.41.11.0-1.01.0-0.50.30.2-0.2-0.2-0.0
Stereotopy head waving duration, day 72.02.44.62.1-2.12.1-1.71.11.1-1.1-0.8-0.5
Locomotion velocity, session 80.10.10.30.3-0.30.3-0.3-0.20.2-0.2-0.30.6
Locomotion distance, session 80.10.20.50.2-0.20.2-0.70.30.5-0.5-0.7-0.0
Degree of sensitization distance0.60.61.6-0.90.9-0.90.9-0.00.4-0.41.2-0.5
Degree of sensitization stereotypy1.92.14.32.1-2.12.1-1.70.80.7-0.7-1.20.3
Conditioned locomotion1.01.12.2-0.60.6-0.60.3-1.3-1.51.5-0.91.5
Cocaine response after cond. corrected0.10.10.3-0.50.5-0.50.6-0.30.0-0.00.4-0.0
Cocaine response after cond. not corrected0.00.10.10.2-0.20.2-0.4-0.00.1-0.1-0.40.2
Cocaine response before conditioning1.61.94.41.6-1.61.6-2.10.60.1-0.1-2.00.8
Saline control response0.30.42.0-0.20.2-0.20.8-0.70.1-0.10.91.4
Bone: connectivity density0.50.71.61.1-1.11.1-1.30.30.6-0.6-0.7-0.4
Bone: cortical apparent density0.91.21.8-1.31.3-1.31.3-1.0-0.80.81.1-0.2
Bone: cortical area2.43.76.02.5-2.52.5-2.41.61.3-1.3-1.70.7
Bone: cortical porosity0.70.81.61.3-1.31.3-1.10.20.2-0.2-0.90.4
Bone: cortical porosity0.30.30.50.7-0.70.7-0.6-0.1-0.20.2-0.70.6
Bone: cortical thickness1.01.62.61.6-1.61.6-1.51.31.0-1.0-0.7-0.1
Bone: cortical thickness0.70.81.50.8-0.80.8-0.71.20.9-0.90.1-1.2
Bone: cortical tissue density0.91.21.8-1.31.3-1.31.3-1.0-0.80.81.1-0.2
Condit. Reinf. active minus inactive responses0.10.10.3-0.30.3-0.30.5-0.2-0.10.10.60.5
Condit. Reinf. active-inactive response ratio0.10.10.4-0.10.1-0.10.0-0.1-0.20.20.10.6
Condit. Reinf. active responses0.20.30.9-0.50.5-0.50.60.20.4-0.41.0-0.2
Condit. Reinf. inactive responses0.40.41.0-0.40.4-0.40.40.40.8-0.80.9-1.0
Incentive salience index mean0.10.10.40.0-0.00.0-0.1-0.2-0.20.2-0.20.7
Condit. Reinf. lever presses0.10.10.4-0.10.1-0.1-0.1-0.7-0.40.4-0.40.5
Condit. Reinf. active minus inactive responses1.41.84.60.4-0.40.4-0.22.01.7-1.71.1-2.2
Condit. Reinf. active-inactive response ratio1.21.43.8-0.20.2-0.20.51.31.4-1.41.8-2.0
Condit. Reinf. active responses0.60.92.00.5-0.50.5-0.51.41.3-1.30.4-1.2
Condit. Reinf. inactive responses0.91.23.61.1-1.11.1-1.50.1-0.10.1-1.91.0
Condit. Reinf. lever presses1.11.52.31.5-1.51.5-1.21.11.3-1.3-0.4-0.3
Condit. Reinf. lever reinforcers received0.30.41.00.3-0.30.3-0.11.01.0-1.00.5-0.7
Conditioned reinforcement - actives0.40.82.71.1-1.11.1-0.30.10.2-0.2-0.31.6
Conditioned reinforcement - inactives0.40.53.80.1-0.10.10.90.10.1-0.10.42.0
Conditioned locomotion0.10.21.30.2-0.20.20.1-0.1-0.20.2-0.11.1
Patch foraging indifference point 0 sec0.61.11.61.2-1.21.2-0.20.71.3-1.30.31.2
Patch foraging indifference point AUC0.91.33.00.7-0.70.7-0.51.71.5-1.50.7-1.5
Delay disc. indifference point, 0s delay1.01.11.91.3-1.31.3-1.41.00.3-0.3-1.30.2
Delay disc. indifference point, 16s delay2.52.75.4-1.91.9-1.92.3-1.3-1.41.41.50.9
Delay disc. indifference point, 2s delay2.93.36.52.1-2.12.1-2.61.71.4-1.4-1.7-0.3
Delay disc. indifference point, 24s delay1.92.13.8-1.61.6-1.61.9-1.1-1.41.41.21.3
Delay disc. indifference point, 4s delay0.30.30.50.3-0.30.3-0.40.70.7-0.7-0.0-0.7
Delay disc. indifference point, 8s delay0.20.30.80.5-0.50.5-0.50.3-0.30.3-0.80.9
Indifference point function ln k0.30.61.21.1-1.11.1-0.60.10.2-0.2-0.81.0
Indifference point function log k0.30.61.21.1-1.11.1-0.60.10.2-0.2-0.81.0
Patch foraging total patch changes 0 sec0.81.42.41.4-1.41.4-0.21.01.5-1.50.41.1
Patch foraging total patch changes 12 sec0.20.30.70.5-0.50.5-0.20.60.8-0.80.20.2
Patch foraging total patch changes 18 sec0.20.30.60.2-0.20.20.30.50.7-0.70.8-0.7
Patch foraging total patch changes 24 sec0.61.02.00.8-0.80.8-0.51.41.3-1.30.4-1.2
Patch foraging total patch changes 6 sec1.11.75.50.2-0.20.21.01.21.7-1.72.3-1.1
Patch foraging time to switch 0 sec2.24.68.4-2.22.2-2.21.3-2.9-2.82.8-0.60.8
Patch foraging water rate 0 sec0.20.50.80.9-0.90.9-0.40.50.7-0.7-0.30.7
Patch foraging water rate 12 sec0.61.32.01.3-1.31.3-0.91.01.4-1.4-0.10.7
Patch foraging water rate 18 sec0.20.30.50.6-0.60.6-0.50.50.7-0.7-0.40.4
Patch foraging water rate 24 sec0.30.40.60.8-0.80.8-0.60.40.6-0.6-0.30.7
Patch foraging water rate 6 sec0.50.71.50.4-0.40.40.40.91.2-1.21.1-0.9
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.10.1-0.1-0.3-0.30.2-0.2-0.1-0.3
Distance traveled before self-admin0.20.20.80.2-0.20.2-0.4-0.30.9-0.9-0.2-0.1
Distance traveled after self-admin0.91.23.40.8-0.80.8-1.90.20.8-0.8-1.4-1.4
Extensor digitorum longus weight3.313.128.24.6-4.64.6-5.32.00.7-0.7-4.70.5
Bone: elastic displacement0.40.41.1-0.70.7-0.70.80.30.3-0.31.0-0.6
Bone: elastic work0.40.51.20.6-0.60.6-0.71.10.8-0.8-0.3-0.8
Bone: endosteal estimation1.12.34.21.8-1.81.8-2.11.31.0-1.0-1.90.4
Bone: endosteal perimeter0.71.53.41.3-1.31.3-1.60.30.4-0.4-1.81.3
Epididymis fat weight1.03.34.81.8-1.81.8-1.72.12.2-2.2-0.2-1.8
Delta time in closed arm before/after self-admin0.80.82.1-0.10.1-0.1-0.6-0.4-1.41.4-1.40.4
Delta time in open arm before/after self-admin2.01.93.51.5-1.51.5-1.01.71.9-1.90.2-0.0
Diff in mean of infusions in LGA sessions1.31.53.4-0.30.3-0.30.81.51.6-1.61.8-1.5
Delay discount exponential model param0.10.10.20.3-0.30.3-0.20.10.4-0.4-0.0-0.4
Extinction: sum of active levers before priming0.50.51.0-1.01.0-1.00.9-0.4-0.60.60.50.1
Active lever presses in extinction session 60.30.21.60.4-0.40.4-0.00.20.2-0.2-0.11.3
Bone: final force4.06.49.53.1-3.13.1-3.02.62.1-2.1-1.9-0.3
Bone: final moment3.55.78.32.9-2.92.9-2.82.72.1-2.1-1.6-0.3
Food consumed during 24 hour testing period1.82.53.81.9-1.91.9-1.61.71.6-1.6-0.60.5
Glucose0.10.10.4-0.00.0-0.00.10.20.3-0.30.3-0.6
Heart weight0.20.30.70.4-0.40.4-0.10.80.8-0.80.10.4
Delay discount hyperbolic model param0.00.00.00.0-0.00.00.2-0.20.1-0.10.1-0.2
Intermittent access intake day 1-15 change0.20.40.8-0.90.9-0.90.6-0.3-0.40.40.2-0.6
Intermittent access intake escalation0.20.40.8-0.90.9-0.90.7-0.4-0.50.50.3-0.4
Intermittent access intake escalation 20.70.81.7-1.31.3-1.30.8-0.6-0.70.70.2-0.4
Intermitt. access day 1 inactive lever presses0.10.41.0-0.60.6-0.61.0-0.1-0.40.40.80.4
Intermitt. access day 15 inactive lever presses0.51.01.71.3-1.31.3-0.70.90.4-0.4-0.91.2
Intermitt. access escalation Index0.81.22.50.7-0.70.7-0.21.41.5-1.50.3-1.6
Intermittent access day 1 total infusions0.50.81.51.2-1.21.2-1.00.50.6-0.6-0.70.3
Intermittent access day 15 total infusions0.00.00.10.2-0.20.2-0.10.00.3-0.3-0.1-0.2
Intermittent access terminal intake (last 3 days)0.20.30.50.6-0.60.6-0.40.50.7-0.7-0.1-0.4
Intermittent access total infusions1.31.62.81.7-1.71.7-1.31.11.1-1.1-0.6-0.2
Intermittent access day 1 locomotion0.30.40.70.6-0.60.6-0.30.80.8-0.8-0.20.1
Intermittent access day 15 total locomotion0.30.61.40.4-0.40.40.40.81.2-1.21.1-0.2
Intermittent access total locomotion0.91.12.11.0-1.01.0-0.31.31.5-1.50.5-0.6
Intermittent access standard deviation0.71.42.31.0-1.01.0-1.41.51.1-1.1-0.9-1.5
Left kidney weight1.98.813.03.4-3.43.4-3.62.92.7-2.7-2.6-0.3
Right kidney weight2.310.414.03.6-3.63.6-3.73.63.2-3.2-2.3-1.7
Cocaine induced anxiety0.71.15.0-0.90.9-0.90.50.00.4-0.41.2-2.2
Post-drug Anxiety1.82.08.3-1.21.2-1.20.90.30.8-0.81.7-2.9
Baseline Anxiety0.20.20.40.5-0.50.5-0.30.60.7-0.7-0.20.2
Tail length0.62.44.52.1-2.12.1-1.61.00.9-0.9-1.40.8
Length with tail0.20.82.40.6-0.60.6-0.7-0.4-0.70.7-1.61.4
Length without tail0.62.13.5-1.61.6-1.60.9-1.6-1.91.9-0.60.8
Times rat made contact with spout1.41.62.91.6-1.61.6-1.60.70.3-0.3-1.70.9
Lifetime Intake1.72.03.71.9-1.91.9-1.51.21.1-1.1-0.9-0.1
Liver weight, left0.40.60.8-0.90.9-0.90.9-0.9-0.70.70.40.4
Liver weight, right0.71.23.2-0.90.9-0.90.5-1.1-1.81.8-0.60.1
Locomotor activity0.00.00.1-0.10.1-0.10.20.1-0.30.30.00.4
Locomotor testing distance0.10.20.50.4-0.40.4-0.10.70.4-0.40.3-0.1
Locomotor testing rearing0.20.30.5-0.70.7-0.70.6-0.2-0.30.30.40.6
Locomotion in novel chamber0.91.13.30.2-0.20.2-0.30.81.8-1.80.8-1.3
Locomotion in novel chamber post-restriction1.72.87.8-1.41.4-1.41.40.51.3-1.32.4-2.8
Fecal boli incidents, locomotor time 10.50.72.0-0.60.6-0.60.3-1.4-1.31.3-0.0-0.3
Change in fecal boli incidents, locomotor task0.90.92.10.8-0.80.8-0.31.41.4-1.40.00.2
Time >=10cm from walls, locomotor time 10.90.91.71.3-1.31.3-1.00.90.6-0.6-0.8-0.2
Bouts of movement, locomotor time 12.52.95.2-2.22.2-2.22.3-1.1-0.70.72.00.5
Total resting periods, locomotor time 13.03.45.5-2.32.3-2.32.3-1.5-1.31.31.80.8
Rest time, locomotor task time 11.92.45.5-1.21.2-1.20.7-1.8-2.32.3-0.41.5
Distance moved, locomotor task time 11.42.14.21.3-1.31.3-0.72.02.1-2.10.2-1.2
Vertical activity count, locomotor time 11.63.98.11.7-1.71.7-1.22.42.8-2.80.3-1.8
Time >=10cm from walls, locomotor time 21.82.64.72.2-2.22.2-1.80.90.5-0.5-1.71.3
Bouts of movement, locomotor time 20.20.41.40.4-0.40.4-0.6-0.2-0.70.7-1.20.2
Total resting periods, locomotor time 20.30.62.10.6-0.60.6-0.9-0.2-0.70.7-1.40.3
Rest time, locomotor task time 20.30.32.60.3-0.30.3-0.4-0.1-0.00.0-0.21.6
Distance moved, locomotor task time 20.40.50.90.7-0.70.7-0.41.00.6-0.6-0.5-0.9
Vertical activity count, locomotor time 20.50.71.60.6-0.60.6-0.21.01.2-1.20.3-1.3
Light reinforcement 10.10.10.4-0.40.4-0.40.5-0.30.2-0.20.60.3
Light reinforcement 20.10.21.00.3-0.30.30.30.00.4-0.40.41.0
Bone: marrow area0.92.03.71.6-1.61.6-1.91.20.9-0.9-1.80.3
Bone: maximum diameter1.73.25.12.2-2.22.2-2.31.31.3-1.3-1.50.9
Bone: maximum force3.25.68.83.0-3.03.0-2.92.31.9-1.9-1.9-0.1
Bone: maximum moment2.84.87.52.7-2.72.7-2.62.31.8-1.8-1.6-0.1
Mean time between licks in bursts0.10.20.5-0.40.4-0.40.70.2-0.40.40.7-0.2
Mean num. licks in bursts4.87.410.53.2-3.23.2-3.23.22.2-2.2-2.2-0.8
Cd content in liver1.31.44.6-1.21.2-1.21.5-0.11.0-1.02.1-0.4
Co content in liver0.50.61.70.2-0.20.20.30.81.3-1.30.90.2
Cu content in liver1.21.42.61.1-1.11.1-0.71.41.6-1.60.1-1.0
Fe content in liver0.50.61.6-0.50.5-0.50.80.50.9-0.91.3-0.7
K content in liver0.40.30.80.6-0.60.6-0.30.30.9-0.90.20.4
Mg content in liver0.10.10.70.3-0.30.3-0.2-0.40.0-0.0-0.30.9
Mn content in liver0.40.51.01.0-1.01.0-0.80.40.1-0.1-0.70.4
Na content in liver3.33.56.32.4-2.42.4-2.51.20.4-0.4-2.40.1
Rb content in liver2.12.49.2-1.11.1-1.12.00.41.4-1.43.0-0.6
Se content in liver0.20.30.40.5-0.50.5-0.60.50.5-0.5-0.4-0.7
Sr content in liver0.60.51.01.0-1.01.0-0.80.20.3-0.3-0.70.5
Zn content in liver1.01.11.71.3-1.31.3-1.30.50.9-0.9-0.90.6
Bone: minimum diameter1.73.04.92.1-2.12.1-2.21.30.9-0.9-2.11.4
Time in familiar zone, hab. session 10.80.82.6-0.60.6-0.60.90.40.7-0.71.6-1.2
Time in novel zone, hab. session 12.12.17.10.8-0.80.8-1.3-1.0-1.21.2-2.72.1
Total zone transitions, hab. session 12.83.95.52.4-2.42.4-2.21.82.2-2.2-0.7-0.6
Total locomotion distance, hab. session 15.07.19.73.1-3.13.1-2.92.72.9-2.9-1.3-0.9
Locomotion velocity, hab. session 14.26.08.42.7-2.72.7-2.42.72.9-2.9-0.7-1.5
Time in familiar zone, hab. session 20.40.41.30.4-0.40.4-0.41.20.6-0.6-0.0-1.1
Time in novel zone, hab. session 20.00.00.20.0-0.00.00.1-0.50.0-0.00.10.4
Total zone transitions, hab. session 22.53.35.02.2-2.22.2-1.81.81.9-1.9-0.7-0.5
Total locomotion distance, hab. session 23.14.15.52.4-2.42.4-2.12.12.1-2.1-0.8-1.0
Locomotion velocity, hab. session 23.64.86.72.6-2.62.6-2.42.32.3-2.3-1.0-1.0
Novel to familiar place preference ratio0.60.62.1-0.70.7-0.71.3-0.20.2-0.21.5-0.3
Novelty place preference0.50.51.7-0.70.7-0.71.2-0.30.1-0.11.3-0.3
Time in novel zone, NPP test0.50.62.0-0.70.7-0.71.2-0.20.3-0.31.4-0.5
Total zone transitions, NPP test1.62.33.82.0-2.02.0-1.81.21.4-1.4-0.7-0.0
Total locomotion distance, NPP test1.62.33.11.5-1.51.5-1.51.81.7-1.7-0.4-1.4
Locomotion velocity, NPP test1.31.82.41.4-1.41.4-1.51.51.4-1.4-0.5-1.1
Intraocular pressure0.10.10.40.1-0.10.1-0.6-0.1-0.40.4-0.70.0
Delta distance traveled before/after self-admin0.50.61.40.9-0.90.9-1.20.3-0.10.1-1.10.1
Delta ambulatory time before/after self-admin0.70.82.11.0-1.01.0-1.50.40.0-0.0-1.50.3
Parametrial fat weight3.89.014.93.2-3.23.2-2.43.53.9-3.9-0.2-1.5
Pavlov. Cond. lever latency0.70.92.3-0.20.2-0.20.61.51.2-1.21.3-1.1
Pavlov. Cond. magazine entry latency1.21.64.11.4-1.41.4-1.8-0.3-0.20.2-2.00.7
Pavlov. Cond. change in total contacts1.71.84.10.2-0.20.2-0.9-1.7-1.71.7-2.01.7
Pavlov. Cond. index score0.91.12.90.6-0.60.6-1.0-1.3-1.11.1-1.71.0
Pavlov. Cond. latency score0.70.92.20.7-0.70.7-1.0-1.2-0.80.8-1.50.9
Pavlov. Cond. lever contacts1.01.23.60.8-0.80.8-1.3-1.1-0.90.9-1.91.1
Pavlov. Cond. magazine entry number1.01.23.7-0.70.7-0.71.21.01.1-1.11.9-1.1
Pavlov. Cond. intertrial magazine entries1.21.44.1-1.11.1-1.11.40.90.7-0.72.0-1.4
Pavlov. Cond. lever-magazine prob. diff.0.91.13.10.7-0.70.7-1.2-1.1-0.90.9-1.80.8
Pavlov. Cond. response bias1.51.85.40.7-0.70.7-1.3-1.4-1.51.5-2.31.3
Pavlov. Cond. lever latency0.91.32.3-1.51.5-1.51.0-0.9-1.11.10.60.0
Pavlov. Cond. magazine entry latency1.21.53.4-0.90.9-0.91.0-1.5-1.81.8-0.30.9
Pavlov. Cond. change in total contacts0.40.71.20.3-0.30.30.51.11.1-1.11.1-0.9
Pavlov. Cond. index score0.00.00.10.3-0.30.30.2-0.1-0.10.10.00.3
Pavlov. Cond. latency score0.10.10.10.3-0.30.30.1-0.2-0.20.2-0.20.4
Pavlov. Cond. lever contacts0.81.12.11.4-1.41.4-0.90.80.9-0.9-0.7-0.0
Pavlov. Cond. magazine entry number1.41.73.01.3-1.31.3-1.71.31.5-1.5-0.8-0.6
Pavlov. Cond. intertrial magazine entries1.62.44.11.7-1.71.7-2.01.51.7-1.7-1.0-0.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.1-0.10.10.4-0.3-0.30.3-0.10.4
Pavlov. Cond. response bias0.10.10.30.5-0.50.50.10.20.3-0.30.0-0.1
Time in closed arm before self-admin0.30.40.80.7-0.70.7-0.30.50.9-0.90.30.0
Time in closed arm after self-admin0.40.41.3-0.70.7-0.70.5-0.3-0.30.30.3-1.2
Time in open arm before self-admin1.61.73.1-1.81.8-1.81.1-1.3-1.21.20.4-0.3
Time in open arm after self-admin1.11.21.81.3-1.31.3-1.30.71.0-1.0-0.90.8
Bone: periosteal estimation2.45.19.02.8-2.82.8-3.01.91.5-1.5-2.50.6
Bone: periosteal perimeter1.52.54.01.9-1.91.9-2.01.01.2-1.2-1.61.1
Bone: post-yield work2.13.15.42.3-2.32.3-1.81.11.6-1.6-1.01.2
Progressive ratio test 1 active lever presses0.30.41.40.6-0.60.6-0.70.50.4-0.4-0.4-1.2
Progressive ratio test 1 breakpoint0.30.41.40.5-0.50.5-0.60.40.2-0.2-0.4-1.2
Progressive ratio test 1 inactive lever presses0.10.10.40.6-0.60.60.10.30.1-0.10.20.3
Progressive ratio test 2 active lever presses0.20.30.80.5-0.50.5-0.2-0.6-0.50.5-0.40.9
Progressive ratio test 2 breakpoint0.20.30.80.4-0.40.4-0.1-0.6-0.50.5-0.40.9
Progressive ratio test 2 inactive lever presses0.30.41.01.0-1.01.0-0.50.30.2-0.2-0.60.4
Incentive Sensitization - Responses1.11.68.20.8-0.80.8-0.1-1.2-1.11.1-0.82.9
Incentive Sensitization - Breakpoint1.31.79.00.9-0.90.9-0.1-1.0-0.90.9-0.73.0
Sum of active levers in priming session hrs 5-60.80.71.2-1.11.1-1.11.0-0.6-0.70.70.60.1
Progressive ratio0.20.31.00.4-0.40.40.10.40.5-0.50.6-1.0
Food seeking constrained by brief footshock0.81.02.0-1.01.0-1.01.4-1.0-0.80.81.01.2
Seeking ratio, punishment vs. effort0.50.73.6-0.10.1-0.1-0.2-0.6-0.80.8-1.01.9
Retroperitoneal fat weight1.56.512.61.9-1.91.9-1.73.33.5-3.50.8-2.8
Reaction time number correct0.61.22.1-1.41.4-1.41.0-1.0-1.11.10.40.3
Reaction time mean minus median0.20.51.20.7-0.70.7-0.20.71.1-1.10.4-0.2
Reaction time mean minus median AUC0.20.61.20.6-0.60.60.40.61.1-1.11.00.3
Reaction time num false alarms0.50.71.4-1.11.1-1.11.2-0.1-0.30.30.80.1
Reaction time num false alarms AUC0.30.50.9-1.01.0-1.00.9-0.1-0.40.40.40.6
Reaction time trials correct on left0.61.22.1-1.41.4-1.41.0-1.0-1.11.10.40.3
Reaction time trials on left0.61.22.1-1.41.4-1.41.0-1.0-1.01.00.40.3
Reaction time mean0.20.40.80.4-0.40.4-0.30.80.9-0.90.3-0.6
Reaction time mean AUC0.00.10.20.2-0.20.2-0.00.30.4-0.40.1-0.0
Median of all reaction times0.20.20.60.3-0.30.3-0.40.60.6-0.60.1-0.7
Reaction time omissions0.20.31.9-0.20.2-0.20.4-0.7-0.40.4-0.21.4
Reaction time false alarm rate0.00.00.2-0.10.1-0.10.30.2-0.10.10.00.4
Reaction time premature initiation rate0.91.23.81.0-1.01.0-1.60.1-0.30.3-2.01.0
Reaction time premature initiations0.51.03.10.1-0.10.1-0.9-0.7-1.01.0-1.81.5
Std. dev. reaction times0.30.61.10.8-0.80.8-0.30.81.1-1.10.3-0.3
Reaction time trials completed0.61.22.1-1.41.4-1.41.0-1.0-1.01.00.40.3
Reaction time trials AUC0.50.91.6-1.31.3-1.30.8-0.8-0.90.90.20.2
Run reversals in cocaine runway, females2.92.97.12.0-2.02.0-2.71.10.8-0.8-2.1-0.7
Run reversals in cocaine runway, males0.30.30.8-0.20.2-0.20.9-0.2-0.60.60.30.9
Latency to leave start box in cocaine runway0.30.30.70.2-0.20.20.40.70.8-0.80.7-0.1
Latency to leave start box in cocaine runway, F0.10.10.2-0.40.4-0.40.4-0.4-0.30.3-0.10.3
Latency to leave start box in cocaine runway, M1.11.02.10.7-0.70.70.01.41.5-1.51.2-0.3
Std. dev. time between licks in bursts0.10.20.50.1-0.10.10.10.50.5-0.50.5-0.7
Total sessions with >9 infusions4.45.49.13.0-3.03.0-2.91.81.5-1.5-2.3-0.1
Short access day 1 total inactive lever presses1.11.43.41.5-1.51.5-0.90.5-0.10.1-1.11.8
Short access day 10 total inactive lever presses0.61.42.9-0.80.8-0.81.2-0.9-1.71.70.41.7
Short access day 1 total infusions1.11.53.41.5-1.51.5-1.60.6-0.30.3-1.80.0
Short access day 10 total infusions2.63.36.12.5-2.52.5-2.20.90.7-0.7-2.00.9
Short access total infusions3.24.17.52.7-2.72.7-2.41.61.2-1.2-1.8-0.0
Short access day 1 locomotion0.60.71.81.0-1.01.0-0.90.6-0.00.0-1.30.5
Short access day 10 total locomotion1.63.05.71.8-1.81.8-1.82.41.7-1.7-1.1-1.0
Short access total locomotion3.54.26.42.3-2.32.3-2.02.52.2-2.2-1.0-0.7
One hour access (0.3 mA shock)0.30.30.60.4-0.40.4-0.00.70.8-0.80.6-0.5
Compulsive drug intake0.20.31.6-0.20.2-0.20.6-0.2-0.10.10.71.3
One hour access (shock baseline)0.30.41.8-0.10.1-0.10.20.60.8-0.80.4-1.3
Social response proportion0.30.30.80.2-0.20.20.50.80.8-0.80.90.1
Social responses0.40.61.7-0.60.6-0.61.3-0.2-0.00.01.01.1
Social time0.60.82.7-0.50.5-0.51.3-0.6-0.50.51.11.6
Soleus weight2.26.69.53.1-3.13.1-2.92.62.6-2.6-1.3-0.8
Bone: stiffness2.54.16.52.6-2.62.6-2.41.91.6-1.6-1.50.2
Tibialis anterior weight5.418.231.05.4-5.45.4-5.63.53.2-3.2-3.4-0.4
Time to tail flick, vehicle, before self-admin0.20.20.50.5-0.50.5-0.20.70.5-0.50.60.0
Time to tail flick, vehicle, after self-admin1.41.92.6-1.41.4-1.41.6-1.5-1.61.60.41.2
Time to tail flick, test, before self-admin1.01.07.40.8-0.80.80.1-0.1-0.10.10.22.7
Time to tail flick, test, after self-admin0.50.51.4-0.40.4-0.4-0.1-0.9-0.90.9-0.91.2
Delta time to tail flick, vehicle, before/after SA0.20.20.3-0.50.5-0.50.4-0.6-0.40.4-0.5-0.1
Delta time to tail flick, test, before/after SA0.30.31.7-0.00.0-0.0-0.70.10.1-0.1-0.7-1.3
Tibia length0.10.20.50.1-0.10.10.20.70.7-0.70.7-0.0
Ambulatory time before self-admin0.10.20.6-0.20.2-0.20.0-0.40.8-0.80.3-0.5
Ambulatory time after self-admin0.80.93.10.7-0.70.7-1.80.00.7-0.7-1.4-1.1
Bone: tissue strength0.10.10.50.3-0.30.3-0.40.1-0.20.2-0.70.4
Total heroin consumption0.40.40.7-0.80.8-0.80.7-0.4-0.60.60.3-0.5
Bone: trabecular number0.71.21.71.2-1.21.2-1.30.91.1-1.1-0.5-0.9
Bone: trabecular spacing0.91.21.8-1.01.0-1.01.2-1.2-1.41.40.10.8
Bone: trabecular thickness3.34.28.21.6-1.61.6-1.42.92.4-2.40.5-2.9
Bone: trabecular tissue density0.00.10.20.0-0.00.00.10.30.1-0.10.5-0.4
Water consumed over 24 hours1.82.48.5-0.40.4-0.40.1-2.0-1.81.8-1.32.9
Number of responses in last shaping day0.50.51.70.0-0.00.0-0.5-0.3-1.11.1-1.3-0.3