Hub : Genes

Slc25a45

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression Slc25a45 0.13 0.09 8.5e-03 0.03 0.04 0.04 0.05 4.7e-02 3.0e-02 3.4e-02 2.2e-02
2 BLA gene expression Slc25a45 0.19 0.09 3.4e-11 0.17 0.2 0.19 0.19 1.8e-09 6.4e-11 1.9e-10 1.3e-10
3 PL gene expression Slc25a45 0.19 0.08 0.0e+00 0.29 0.28 0.28 0.28 2.5e-32 1.4e-30 3.7e-31 4.8e-31
4 NAcc gene expression Slc25a45 0.14 0.06 0.0e+00 0.18 0.18 0.17 0.18 7.4e-21 1.9e-20 4.8e-19 7.2e-21
5 OFC gene expression Slc25a45 0.19 0.1 2.6e-04 0.18 0.17 0.16 0.17 4.7e-05 6.8e-05 1.2e-04 8.1e-05
6 LHb gene expression Slc25a45 0.3 0.14 1.2e-05 0.14 0.12 0.06 0.13 3.3e-04 7.2e-04 1.6e-02 5.6e-04
7 Brain gene expression Slc25a45 0.22 0.1 0.0e+00 0.19 0.18 0.14 0.17 2.5e-17 2.7e-16 2.5e-13 7.1e-16
8 IL gene expression Slc25a45 0.18 0.1 2.2e-03 0.04 0.08 0.08 0.07 3.9e-02 5.7e-03 6.2e-03 8.3e-03
9 Adipose gene expression Slc25a45 0.4 0.13 0.0e+00 0.23 0.23 0.23 0.23 8.6e-25 3.1e-25 1.3e-25 1.6e-25
10 pVTA gene expression Slc25a45 0.26 0.11 6.5e-11 0.2 0.21 0.18 0.2 7.3e-09 2.5e-09 3.9e-08 5.2e-09
11 Brain mRNA stability Slc25a45 0.05 0.04 5.6e-03 0 0.02 0.01 0 3.1e-01 6.1e-03 5.6e-02 9.3e-02
12 Liver gene expression Slc25a45 0.07 0.04 1.2e-04 0.02 0.01 0.01 0.01 9.2e-04 1.2e-02 6.9e-03 9.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.40.72.6-0.8-1.20.6-0.50.60.50.8-1.60.1-0.2-1.00.5
Area under the delay curve0.10.10.40.30.0-0.10.4-0.1-0.2-0.4-0.3-0.50.3-0.60.1
BMI with tail3.09.823.5-3.1-4.12.9-2.62.92.93.0-4.81.3-1.9-3.82.6
BMI without tail1.53.16.5-1.4-2.21.7-1.41.71.61.5-2.50.5-1.2-2.51.9
Body weight4.117.221.9-4.4-4.74.2-4.14.24.24.3-4.53.4-3.7-4.03.9
Weight adjusted by age2.22.53.4-1.6-1.61.7-1.71.71.51.8-1.41.7-1.5-1.11.4
Bone surface4.07.111.9-2.8-3.32.8-2.72.82.62.8-3.52.2-1.9-2.11.9
Bone volume1.32.36.2-1.6-2.11.5-1.41.51.41.6-2.51.0-0.7-1.10.8
Breakpoint value in progressive ratio session3.43.85.3-2.1-2.01.9-2.01.92.02.3-1.92.1-1.7-1.61.6
Number of licking bursts0.30.30.5-0.7-0.60.5-0.60.50.70.6-0.70.6-0.4-0.50.3
Context. condit. distance diff. score2.02.53.31.71.6-1.71.7-1.7-1.7-1.81.3-1.61.51.1-1.2
Locomotion velocity, session 10.10.10.30.10.00.1-0.10.10.20.00.30.1-0.4-0.10.6
Locomotion distance, session 10.60.81.9-0.6-1.10.8-0.60.80.70.8-1.20.1-0.6-1.41.0
Locomotion velocity, session 23.13.64.7-1.8-2.21.9-1.81.92.02.0-2.11.4-1.7-2.11.9
Locomotion distance, session 20.81.22.8-0.9-1.21.0-0.81.01.01.1-1.30.4-0.9-1.71.3
Locomotion velocity, session 30.10.20.80.3-0.0-0.40.5-0.4-0.4-0.3-0.2-0.90.5-0.0-0.2
Locomotion distance, session 30.00.00.10.10.2-0.20.2-0.2-0.2-0.10.2-0.30.20.1-0.1
Stereotopy head waving bouts, day 30.50.61.41.00.4-0.80.9-0.8-0.8-1.00.2-1.20.80.4-0.3
Stereotopy head waving duration, day 30.70.91.51.20.6-0.91.0-0.9-0.9-1.20.5-1.20.90.7-0.7
Locomotion velocity, session 70.50.51.60.50.2-0.80.9-0.7-0.8-0.5-0.5-1.31.1-0.1-0.6
Locomotion distance, session 70.10.10.30.00.1-0.30.4-0.3-0.4-0.1-0.2-0.50.2-0.60.2
Stereotopy head waving bouts, day 70.20.20.60.40.1-0.30.4-0.4-0.3-0.5-0.3-0.60.70.4-0.8
Stereotopy head waving duration, day 70.91.12.8-1.1-1.41.1-1.01.11.10.9-1.70.6-0.6-1.10.6
Locomotion velocity, session 81.01.22.1-1.1-0.91.1-1.11.11.11.1-0.41.2-1.4-0.91.5
Locomotion distance, session 80.20.30.70.50.1-0.50.6-0.5-0.6-0.5-0.1-0.80.60.1-0.3
Degree of sensitization distance0.10.10.2-0.1-0.2-0.10.2-0.2-0.3-0.0-0.4-0.30.2-0.30.2
Degree of sensitization stereotypy0.50.51.4-0.9-0.90.7-0.60.70.70.7-1.20.5-0.2-0.50.1
Conditioned locomotion1.72.02.4-1.4-1.41.5-1.51.41.41.4-1.11.5-1.5-1.21.5
Cocaine response after cond. corrected1.61.82.41.51.3-1.41.4-1.5-1.5-1.41.4-1.51.00.9-0.7
Cocaine response after cond. not corrected1.21.41.81.31.1-1.21.3-1.3-1.3-1.21.2-1.30.90.9-0.6
Cocaine response before conditioning0.70.81.2-1.1-1.00.9-1.01.10.91.0-1.01.0-0.7-0.60.5
Saline control response4.66.06.9-2.6-2.42.5-2.52.62.62.5-2.02.4-2.5-2.32.5
Bone: connectivity density2.23.46.5-1.9-2.31.8-1.71.81.72.0-2.51.3-1.3-2.01.6
Bone: cortical apparent density0.30.41.0-0.6-0.30.6-0.60.50.80.5-0.30.6-0.7-1.00.6
Bone: cortical area0.60.91.6-1.2-1.11.0-1.01.00.81.3-1.00.9-0.8-0.40.6
Bone: cortical porosity0.10.10.5-0.3-0.50.3-0.20.30.10.3-0.7-0.0-0.1-0.60.3
Bone: cortical porosity0.70.71.1-0.8-1.00.8-0.80.90.80.8-1.00.6-0.7-1.00.9
Bone: cortical thickness2.84.66.3-2.4-1.82.2-2.22.12.22.5-1.22.3-2.4-1.92.3
Bone: cortical thickness0.70.81.7-0.9-0.40.8-0.80.80.81.00.11.0-1.3-0.91.2
Bone: cortical tissue density0.40.51.2-0.6-0.40.7-0.80.60.90.6-0.40.8-0.8-1.10.8
Condit. Reinf. active minus inactive responses0.20.20.6-0.3-0.40.4-0.40.40.30.5-0.60.3-0.3-0.80.5
Condit. Reinf. active-inactive response ratio0.00.00.20.1-0.00.2-0.10.20.10.1-0.10.1-0.2-0.50.2
Condit. Reinf. active responses0.10.10.4-0.2-0.40.1-0.10.10.00.4-0.6-0.00.1-0.40.0
Condit. Reinf. inactive responses0.10.10.30.0-0.2-0.30.3-0.3-0.30.1-0.5-0.40.60.3-0.5
Incentive salience index mean0.30.41.0-0.5-0.80.6-0.50.50.50.7-1.00.2-0.4-1.00.6
Condit. Reinf. lever presses0.30.41.1-0.6-1.00.6-0.60.60.60.7-1.10.4-0.4-0.50.4
Condit. Reinf. active minus inactive responses0.20.20.80.40.2-0.30.4-0.3-0.5-0.3-0.1-0.30.70.6-0.9
Condit. Reinf. active-inactive response ratio0.91.02.40.90.5-0.80.9-0.8-0.9-0.80.0-0.91.41.4-1.5
Condit. Reinf. active responses0.10.10.4-0.2-0.30.2-0.10.30.10.2-0.60.00.1-0.4-0.2
Condit. Reinf. inactive responses0.50.62.1-0.6-0.60.7-0.60.70.60.6-0.60.4-0.7-1.50.9
Condit. Reinf. lever presses2.22.94.1-1.9-1.91.8-1.81.91.82.0-2.01.7-1.2-1.10.9
Condit. Reinf. lever reinforcers received0.20.30.7-0.5-0.60.6-0.50.70.50.6-0.90.5-0.2-0.60.1
Conditioned reinforcement - actives0.40.41.50.50.4-0.60.5-0.5-0.5-0.30.4-0.30.71.2-0.8
Conditioned reinforcement - inactives7.18.010.12.72.9-2.92.8-2.9-2.9-2.72.4-2.23.03.1-3.2
Conditioned locomotion9.311.214.13.33.6-3.43.3-3.3-3.3-3.23.3-2.83.23.8-3.5
Patch foraging indifference point 0 sec0.00.00.10.10.2-0.30.2-0.2-0.1-0.20.1-0.20.30.1-0.1
Patch foraging indifference point AUC3.84.45.6-2.3-2.12.3-2.32.32.32.4-1.92.1-1.9-1.61.6
Delay disc. indifference point, 0s delay0.40.51.41.00.4-0.50.9-0.5-0.4-1.10.1-1.20.6-0.30.1
Delay disc. indifference point, 16s delay0.90.91.50.90.9-1.01.0-1.1-1.1-0.90.3-1.11.20.4-1.2
Delay disc. indifference point, 2s delay0.10.10.30.40.1-0.30.4-0.3-0.3-0.40.0-0.50.40.2-0.2
Delay disc. indifference point, 24s delay0.10.10.30.30.4-0.30.3-0.2-0.3-0.30.6-0.2-0.1-0.20.2
Delay disc. indifference point, 4s delay0.20.20.40.50.3-0.30.5-0.3-0.4-0.50.2-0.60.2-0.50.3
Delay disc. indifference point, 8s delay0.10.10.40.30.10.00.2-0.0-0.1-0.50.0-0.3-0.0-0.60.4
Indifference point function ln k8.812.214.73.73.6-3.83.8-3.8-3.8-3.63.5-3.63.02.7-2.6
Indifference point function log k8.812.214.73.73.6-3.83.8-3.8-3.8-3.63.5-3.63.02.7-2.6
Patch foraging total patch changes 0 sec0.00.00.10.00.3-0.20.1-0.1-0.0-0.10.3-0.0-0.00.00.1
Patch foraging total patch changes 12 sec5.36.98.4-2.9-2.62.6-2.72.82.72.9-2.52.4-2.3-2.62.2
Patch foraging total patch changes 18 sec0.60.81.3-0.9-1.00.9-0.91.11.10.9-1.10.6-0.5-0.70.5
Patch foraging total patch changes 24 sec2.73.34.3-2.0-1.61.9-2.02.02.11.9-1.22.0-1.9-1.31.7
Patch foraging total patch changes 6 sec1.11.72.7-1.6-1.21.2-1.21.21.41.4-1.11.1-1.2-1.41.3
Patch foraging time to switch 0 sec1.93.07.6-1.8-2.31.6-1.51.71.71.6-2.81.0-0.9-1.91.1
Patch foraging water rate 0 sec4.47.112.12.83.2-2.62.4-2.6-2.5-2.63.5-1.82.03.1-2.4
Patch foraging water rate 12 sec8.913.723.34.04.4-3.73.6-3.9-3.8-3.84.8-2.92.63.7-2.7
Patch foraging water rate 18 sec3.44.67.02.42.4-2.22.2-2.4-2.3-2.32.6-1.81.62.0-1.3
Patch foraging water rate 24 sec4.66.510.02.82.8-2.42.4-2.5-2.5-2.93.2-2.01.92.7-2.1
Patch foraging water rate 6 sec4.26.211.72.63.0-2.52.4-2.6-2.5-2.53.4-1.91.62.5-1.8
Seeking ratio, delayed vs. immediate footshock0.10.10.4-0.10.1-0.30.2-0.3-0.2-0.2-0.3-0.30.3-0.6-0.2
Distance traveled before self-admin0.60.61.1-0.8-1.00.9-0.80.90.90.7-1.10.8-0.5-0.50.5
Distance traveled after self-admin0.20.20.4-0.6-0.50.5-0.60.50.50.5-0.50.6-0.3-0.30.2
Extensor digitorum longus weight8.332.637.3-5.9-6.15.9-5.86.05.95.9-5.65.1-5.4-5.55.4
Bone: elastic displacement1.21.44.41.01.6-1.11.1-1.1-1.3-0.92.1-0.70.41.2-0.5
Bone: elastic work0.81.02.1-1.2-0.60.9-0.90.90.81.20.01.0-1.4-0.91.4
Bone: endosteal estimation0.91.93.61.30.5-1.31.5-1.3-1.6-1.4-0.0-1.91.81.3-1.5
Bone: endosteal perimeter1.22.64.71.50.6-1.51.6-1.5-1.7-1.5-0.0-2.02.21.8-2.0
Epididymis fat weight2.86.58.02.62.2-2.52.7-2.7-2.6-2.61.7-2.82.82.6-2.7
Delta time in closed arm before/after self-admin0.20.10.8-0.10.10.0-0.10.00.00.10.40.2-0.6-0.50.9
Delta time in open arm before/after self-admin0.10.10.2-0.3-0.20.2-0.30.20.30.2-0.30.40.10.3-0.4
Diff in mean of infusions in LGA sessions0.40.41.2-0.7-0.40.6-0.70.60.50.8-0.31.1-0.7-0.30.5
Delay discount exponential model param0.10.10.4-0.30.00.1-0.30.10.20.30.20.4-0.20.6-0.2
Extinction: sum of active levers before priming5.35.37.0-2.4-2.52.2-2.22.22.32.5-2.62.0-1.9-2.52.1
Active lever presses in extinction session 62.42.33.8-1.5-1.61.7-1.81.71.61.7-1.12.0-1.5-0.51.2
Bone: final force3.04.96.6-2.3-2.62.4-2.32.32.22.2-2.42.1-2.0-1.82.0
Bone: final moment2.74.35.8-2.2-2.42.2-2.22.12.12.1-2.21.9-1.8-1.71.9
Food consumed during 24 hour testing period0.10.10.3-0.20.00.2-0.30.20.40.20.20.5-0.10.4-0.2
Glucose2.03.14.81.91.3-1.81.9-1.9-1.7-1.90.7-2.22.11.3-1.8
Heart weight3.75.26.72.32.3-2.52.5-2.3-2.6-2.42.0-2.42.21.8-1.9
Delay discount hyperbolic model param0.10.10.4-0.20.00.0-0.20.00.10.30.20.4-0.10.6-0.2
Intermittent access intake day 1-15 change1.01.02.60.81.1-1.00.7-0.8-0.8-0.81.1-0.40.91.6-1.2
Intermittent access intake escalation0.80.81.90.80.9-0.90.8-0.8-0.8-0.80.9-0.50.91.4-1.1
Intermittent access intake escalation 20.30.31.10.40.6-0.50.3-0.4-0.4-0.40.70.10.41.1-0.8
Intermitt. access day 1 inactive lever presses2.62.83.31.71.7-1.61.7-1.8-1.8-1.71.3-1.61.81.6-1.8
Intermitt. access day 15 inactive lever presses3.13.44.91.81.8-1.81.8-1.9-1.9-1.61.4-1.62.12.2-2.2
Intermitt. access escalation Index3.32.95.21.91.6-1.72.0-1.8-1.8-1.81.2-2.31.70.8-1.3
Intermittent access day 1 total infusions5.86.711.12.72.0-2.72.9-2.6-2.6-2.51.1-3.33.22.2-2.7
Intermittent access day 15 total infusions9.510.713.33.33.0-3.43.4-3.3-3.3-3.02.3-3.33.63.5-3.6
Intermittent access terminal intake (last 3 days)6.77.310.22.72.2-2.82.8-2.7-2.7-2.51.6-2.83.23.1-3.1
Intermittent access total infusions5.46.09.12.51.9-2.52.7-2.4-2.4-2.11.1-2.93.02.4-2.8
Intermittent access day 1 locomotion4.04.18.12.11.5-2.12.3-2.1-2.1-1.90.8-2.82.51.4-1.9
Intermittent access day 15 total locomotion5.86.38.32.52.3-2.62.6-2.5-2.5-2.31.7-2.62.92.6-2.8
Intermittent access total locomotion7.07.912.52.82.2-2.83.0-2.8-2.8-2.71.2-3.43.52.7-3.2
Intermittent access standard deviation1.61.72.91.41.3-1.21.2-1.2-1.2-1.21.3-1.01.31.7-1.4
Left kidney weight0.72.02.71.41.2-1.41.4-1.3-1.4-1.50.9-1.41.61.5-1.6
Right kidney weight0.20.52.00.50.5-0.60.4-0.4-0.6-0.60.4-0.30.81.4-1.2
Cocaine induced anxiety0.00.00.2-0.1-0.10.0-0.00.00.00.0-0.10.10.10.5-0.1
Post-drug Anxiety1.21.42.1-1.5-1.21.2-1.31.21.21.3-0.91.4-1.1-0.20.9
Baseline Anxiety2.52.73.6-1.8-1.51.6-1.81.61.61.7-1.11.9-1.8-1.31.7
Tail length0.72.14.0-1.1-0.81.5-1.61.61.41.30.01.9-2.0-0.91.8
Length with tail2.28.111.1-2.9-2.53.0-3.13.03.03.0-1.73.3-3.1-2.02.9
Length without tail2.55.68.0-2.8-2.32.4-2.52.32.42.7-1.92.7-2.3-1.62.0
Times rat made contact with spout0.60.61.8-0.7-0.60.7-0.70.80.80.7-0.60.5-0.8-1.31.0
Lifetime Intake4.55.17.82.41.7-2.42.5-2.3-2.3-2.01.0-2.82.82.1-2.5
Liver weight, left0.00.10.10.30.1-0.20.2-0.2-0.2-0.30.1-0.30.30.4-0.2
Liver weight, right0.00.10.20.20.2-0.30.3-0.2-0.2-0.30.4-0.30.00.40.2
Locomotor activity1.93.16.71.72.2-1.81.7-1.8-1.8-1.72.6-1.21.01.7-1.2
Locomotor testing distance2.64.410.12.12.7-2.12.1-2.1-2.2-2.03.2-1.71.11.9-1.2
Locomotor testing rearing2.33.66.52.02.3-1.92.0-2.0-2.1-1.92.6-1.71.21.5-1.1
Locomotion in novel chamber5.46.79.62.62.4-2.62.5-2.6-2.5-2.62.0-2.42.83.1-2.9
Locomotion in novel chamber post-restriction3.44.04.62.02.0-2.12.0-2.0-2.0-1.91.7-1.92.12.1-2.2
Fecal boli incidents, locomotor time 10.10.10.4-0.2-0.40.2-0.10.20.20.2-0.60.30.40.6-0.5
Change in fecal boli incidents, locomotor task0.10.10.5-0.0-0.10.0-0.0-0.1-0.1-0.00.1-0.2-0.4-0.60.7
Time >=10cm from walls, locomotor time 10.90.92.40.70.1-0.80.9-0.7-0.7-1.0-0.5-1.11.51.0-1.3
Bouts of movement, locomotor time 11.61.72.7-1.4-1.01.5-1.51.31.31.1-1.01.6-1.2-1.50.9
Total resting periods, locomotor time 11.11.21.8-1.2-0.91.3-1.21.11.11.0-1.01.3-0.9-1.20.6
Rest time, locomotor task time 11.41.52.61.31.3-1.11.2-1.2-1.1-1.11.4-0.91.11.6-1.3
Distance moved, locomotor task time 10.10.20.6-0.3-0.50.2-0.20.30.30.3-0.8-0.2-0.0-0.70.3
Vertical activity count, locomotor time 11.51.51.91.21.3-1.31.3-1.3-1.4-1.11.2-1.21.21.1-1.2
Time >=10cm from walls, locomotor time 20.10.10.3-0.1-0.40.3-0.20.30.2-0.2-0.60.00.1-0.0-0.2
Bouts of movement, locomotor time 20.60.61.2-0.8-0.60.7-0.80.70.61.0-0.70.9-0.7-1.10.6
Total resting periods, locomotor time 20.30.30.8-0.6-0.40.5-0.60.40.40.7-0.60.6-0.4-0.90.3
Rest time, locomotor task time 22.63.03.81.91.6-1.61.8-1.7-1.7-1.91.4-1.81.81.7-1.6
Distance moved, locomotor task time 21.21.41.5-1.2-1.11.2-1.21.21.21.2-0.91.1-1.2-1.11.1
Vertical activity count, locomotor time 20.20.21.2-0.00.5-0.2-0.0-0.2-0.10.11.10.4-0.50.30.2
Light reinforcement 10.10.20.70.50.7-0.50.4-0.3-0.3-0.40.8-0.30.20.4-0.3
Light reinforcement 21.01.43.41.10.9-1.01.1-1.0-1.1-1.00.8-0.91.41.8-1.6
Bone: marrow area0.92.03.81.40.5-1.41.5-1.4-1.6-1.5-0.0-2.01.81.3-1.5
Bone: maximum diameter0.20.30.6-0.5-0.80.6-0.60.50.30.5-0.70.5-0.10.6-0.2
Bone: maximum force3.56.010.6-2.6-3.12.5-2.42.52.42.5-3.31.9-1.7-2.11.8
Bone: maximum moment2.95.19.1-2.4-2.92.3-2.22.32.22.3-3.01.7-1.6-1.91.7
Mean time between licks in bursts0.70.92.2-1.0-0.60.7-0.90.81.00.7-0.11.0-1.4-1.11.5
Mean num. licks in bursts0.20.20.30.60.6-0.40.5-0.4-0.5-0.50.6-0.60.2-0.1-0.0
Cd content in liver1.71.83.71.41.4-1.21.1-1.2-1.2-1.31.3-0.81.31.9-1.6
Co content in liver1.51.75.01.41.9-1.31.2-1.3-1.3-1.42.2-0.80.60.8-0.6
Cu content in liver0.30.41.1-0.8-0.60.6-0.50.60.50.7-0.80.3-0.4-1.00.6
Fe content in liver0.10.20.4-0.7-0.40.4-0.40.40.30.5-0.30.4-0.30.20.1
K content in liver1.91.83.6-1.4-1.71.3-1.21.31.31.4-1.90.7-1.0-1.61.3
Mg content in liver0.30.41.7-0.3-0.80.3-0.10.30.30.3-1.3-0.50.1-1.10.3
Mn content in liver2.63.04.0-2.0-1.91.8-1.81.81.82.0-1.81.7-1.4-1.21.2
Na content in liver1.11.21.5-1.1-1.21.2-1.21.21.11.2-0.91.2-1.1-0.41.0
Rb content in liver1.41.83.11.21.2-1.51.6-1.5-1.5-1.30.7-1.81.50.6-1.2
Se content in liver0.10.10.7-0.1-0.2-0.00.0-0.1-0.10.1-0.5-0.10.50.6-0.8
Sr content in liver3.43.14.7-1.8-1.51.9-2.01.91.91.7-1.02.2-1.9-1.11.6
Zn content in liver1.31.42.2-1.1-1.31.2-1.11.21.21.2-1.41.0-1.0-1.51.0
Bone: minimum diameter0.81.53.71.00.4-1.21.4-1.2-1.4-1.1-0.4-1.91.70.6-1.3
Time in familiar zone, hab. session 10.30.20.50.40.3-0.60.6-0.5-0.6-0.30.1-0.70.60.3-0.5
Time in novel zone, hab. session 10.20.21.10.50.7-0.30.3-0.3-0.3-0.61.1-0.0-0.10.30.1
Total zone transitions, hab. session 10.81.11.7-1.1-1.11.0-0.91.01.01.2-1.20.7-0.8-1.30.9
Total locomotion distance, hab. session 10.30.40.80.60.3-0.60.7-0.6-0.6-0.7-0.1-0.90.80.2-0.5
Locomotion velocity, hab. session 10.00.10.20.1-0.2-0.10.2-0.1-0.2-0.2-0.4-0.40.3-0.2-0.1
Time in familiar zone, hab. session 20.10.10.60.10.3-0.20.1-0.1-0.1-0.00.80.1-0.40.10.5
Time in novel zone, hab. session 20.10.10.7-0.2-0.40.3-0.20.30.30.2-0.8-0.00.1-0.6-0.0
Total zone transitions, hab. session 21.72.24.7-1.3-1.81.4-1.21.41.31.3-2.20.6-1.0-2.11.4
Total locomotion distance, hab. session 20.10.20.70.2-0.5-0.00.2-0.0-0.0-0.2-0.9-0.70.3-0.80.2
Locomotion velocity, hab. session 20.20.20.70.4-0.3-0.20.4-0.2-0.2-0.4-0.8-0.90.6-0.4-0.1
Novel to familiar place preference ratio1.11.22.5-1.1-1.31.2-1.11.11.11.1-1.61.0-0.5-0.80.3
Novelty place preference0.50.51.4-0.7-0.90.8-0.70.70.70.7-1.20.6-0.2-0.50.0
Time in novel zone, NPP test0.30.41.0-0.6-0.70.6-0.60.60.60.6-1.00.5-0.2-0.50.0
Total zone transitions, NPP test2.63.75.0-1.8-2.22.0-1.82.02.01.9-2.21.4-1.6-2.11.8
Total locomotion distance, NPP test0.10.20.7-0.1-0.60.3-0.10.30.20.1-0.8-0.2-0.1-0.80.4
Locomotion velocity, NPP test0.10.20.8-0.3-0.60.3-0.20.30.30.3-0.9-0.1-0.1-0.80.4
Intraocular pressure1.11.64.11.11.3-1.00.9-1.0-1.1-1.11.3-0.51.22.0-1.8
Delta distance traveled before/after self-admin0.10.10.30.10.4-0.20.1-0.2-0.3-0.10.50.1-0.10.1-0.0
Delta ambulatory time before/after self-admin0.00.00.3-0.00.3-0.1-0.0-0.1-0.20.00.50.2-0.3-0.10.2
Parametrial fat weight2.34.46.92.11.5-2.22.2-2.1-2.2-2.30.7-2.62.61.7-2.3
Pavlov. Cond. lever latency0.30.40.90.70.8-0.60.5-0.6-0.6-0.60.9-0.30.40.6-0.5
Pavlov. Cond. magazine entry latency0.30.41.6-0.3-0.80.5-0.40.50.50.3-1.2-0.0-0.0-1.00.2
Pavlov. Cond. change in total contacts0.10.10.9-0.3-0.50.2-0.10.30.20.2-0.9-0.10.3-0.3-0.4
Pavlov. Cond. index score0.10.20.5-0.4-0.60.5-0.40.50.50.3-0.70.2-0.2-0.40.2
Pavlov. Cond. latency score0.10.10.4-0.2-0.50.3-0.20.30.30.2-0.60.0-0.1-0.40.2
Pavlov. Cond. lever contacts0.00.00.1-0.2-0.30.1-0.00.10.10.1-0.4-0.1-0.0-0.30.2
Pavlov. Cond. magazine entry number0.20.30.50.50.6-0.70.6-0.7-0.6-0.50.7-0.60.30.4-0.1
Pavlov. Cond. intertrial magazine entries0.60.81.30.51.0-1.00.8-1.0-1.0-0.40.9-0.40.81.1-1.2
Pavlov. Cond. lever-magazine prob. diff.0.40.51.0-0.6-0.80.8-0.60.70.70.6-1.00.4-0.4-0.70.4
Pavlov. Cond. response bias0.10.10.3-0.4-0.40.4-0.30.40.30.3-0.50.3-0.1-0.30.0
Pavlov. Cond. lever latency0.50.61.20.81.0-0.90.9-0.8-0.8-0.91.1-0.80.50.3-0.2
Pavlov. Cond. magazine entry latency3.94.55.6-2.3-2.32.1-2.12.22.12.3-2.41.7-1.8-2.31.8
Pavlov. Cond. change in total contacts1.92.65.3-1.8-1.91.7-1.61.71.61.9-2.31.4-0.9-1.20.5
Pavlov. Cond. index score2.53.25.1-1.9-2.11.9-1.81.91.82.0-2.31.6-1.3-1.51.1
Pavlov. Cond. latency score2.02.54.3-1.7-1.91.7-1.61.71.61.8-2.11.3-1.1-1.30.9
Pavlov. Cond. lever contacts0.50.61.0-0.9-0.80.9-0.90.90.90.9-0.71.0-0.6-0.10.3
Pavlov. Cond. magazine entry number6.98.410.03.13.1-3.02.9-3.1-3.0-3.13.2-2.62.42.8-2.3
Pavlov. Cond. intertrial magazine entries1.31.72.21.51.3-1.31.3-1.3-1.4-1.41.2-1.21.21.4-1.2
Pavlov. Cond. lever-magazine prob. diff.3.13.95.8-2.1-2.32.1-2.02.12.02.2-2.41.7-1.5-1.71.3
Pavlov. Cond. response bias1.82.53.1-1.7-1.71.7-1.71.71.71.8-1.71.6-1.3-1.11.0
Time in closed arm before self-admin0.10.10.3-0.2-0.40.2-0.20.20.20.2-0.60.00.20.2-0.3
Time in closed arm after self-admin0.00.00.10.00.1-0.30.2-0.3-0.20.00.1-0.20.1-0.10.1
Time in open arm before self-admin0.60.61.30.91.0-0.80.8-0.8-0.8-0.91.2-0.90.1-0.30.1
Time in open arm after self-admin0.20.20.70.40.7-0.40.4-0.4-0.4-0.50.9-0.20.10.3-0.2
Bone: periosteal estimation0.10.20.5-0.0-0.4-0.10.2-0.1-0.4-0.0-0.7-0.50.60.7-0.6
Bone: periosteal perimeter0.10.20.8-0.4-0.70.3-0.30.30.10.4-0.90.00.10.3-0.2
Bone: post-yield work1.11.49.7-0.6-1.90.6-0.40.60.60.6-3.1-0.60.8-1.1-0.4
Progressive ratio test 1 active lever presses3.53.64.32.11.9-2.02.0-1.9-1.9-1.71.5-2.02.01.9-2.0
Progressive ratio test 1 breakpoint3.23.33.92.01.8-1.91.9-1.8-1.8-1.61.6-1.81.91.9-1.9
Progressive ratio test 1 inactive lever presses1.41.51.81.41.3-1.31.3-1.3-1.3-1.21.0-1.31.20.8-1.1
Progressive ratio test 2 active lever presses5.45.87.52.52.2-2.52.5-2.4-2.4-2.11.7-2.42.72.7-2.7
Progressive ratio test 2 breakpoint6.67.49.32.82.7-2.82.7-2.7-2.7-2.42.3-2.52.93.0-3.0
Progressive ratio test 2 inactive lever presses10.111.614.63.43.2-3.53.5-3.4-3.4-3.32.4-3.53.83.4-3.8
Incentive Sensitization - Responses0.60.61.20.70.6-0.90.8-0.8-0.8-0.50.3-0.81.11.0-1.1
Incentive Sensitization - Breakpoint1.01.01.70.90.8-1.11.0-1.0-1.0-0.60.5-1.01.21.2-1.3
Sum of active levers in priming session hrs 5-61.51.43.9-1.3-1.01.2-1.51.21.21.4-0.72.0-1.00.30.4
Progressive ratio2.63.07.1-1.6-2.31.7-1.51.71.61.5-2.70.8-1.0-2.11.4
Food seeking constrained by brief footshock0.20.20.5-0.6-0.20.4-0.50.30.30.50.00.5-0.7-0.60.7
Seeking ratio, punishment vs. effort2.12.56.81.42.2-1.61.4-1.6-1.6-1.42.6-0.90.81.5-1.0
Retroperitoneal fat weight5.819.021.74.34.1-4.64.6-4.6-4.6-4.43.2-4.54.74.1-4.5
Reaction time number correct0.30.50.9-0.5-0.50.9-0.80.70.60.7-0.10.8-0.9-0.20.7
Reaction time mean minus median3.24.26.0-2.3-2.42.1-2.12.12.22.0-2.52.1-1.6-1.61.4
Reaction time mean minus median AUC1.72.22.9-1.7-1.61.5-1.61.61.71.5-1.51.7-1.3-1.01.1
Reaction time num false alarms0.30.41.10.50.8-0.80.6-0.7-0.6-0.31.1-0.4-0.00.00.3
Reaction time num false alarms AUC0.10.20.8-0.30.1-0.1-0.10.10.00.30.40.2-0.6-0.60.9
Reaction time trials correct on left0.30.50.9-0.5-0.50.9-0.80.70.60.7-0.10.8-0.9-0.20.7
Reaction time trials on left0.40.61.1-0.6-0.61.0-0.90.80.70.8-0.11.0-1.0-0.20.8
Reaction time mean0.10.10.3-0.2-0.30.3-0.40.20.40.0-0.50.40.1-0.1-0.3
Reaction time mean AUC0.10.10.4-0.2-0.30.2-0.30.10.3-0.0-0.60.20.2-0.1-0.4
Median of all reaction times0.10.10.40.30.2-0.10.1-0.2-0.1-0.4-0.2-0.10.50.2-0.6
Reaction time omissions1.41.92.5-1.6-1.41.5-1.41.41.41.5-1.41.3-1.2-1.51.1
Reaction time false alarm rate0.20.30.70.40.6-0.90.6-0.6-0.6-0.40.7-0.50.1-0.10.2
Reaction time premature initiation rate2.83.86.6-1.9-1.61.8-1.91.82.11.8-0.91.9-2.5-2.12.6
Reaction time premature initiations4.46.29.6-2.4-2.02.5-2.62.42.62.5-1.12.6-3.1-2.33.0
Std. dev. reaction times0.91.21.8-1.3-1.21.2-1.21.11.20.9-1.31.2-0.7-0.80.6
Reaction time trials completed0.40.61.1-0.6-0.61.0-0.90.80.70.8-0.11.0-1.0-0.20.8
Reaction time trials AUC0.20.30.7-0.5-0.40.8-0.70.60.50.60.00.7-0.8-0.10.7
Run reversals in cocaine runway, females0.80.72.9-0.7-1.00.6-0.40.60.60.6-1.2-0.1-0.6-1.71.1
Run reversals in cocaine runway, males0.50.51.90.50.9-0.50.4-0.5-0.5-0.51.40.00.11.2-0.5
Latency to leave start box in cocaine runway0.10.10.4-0.0-0.2-0.30.3-0.3-0.20.0-0.6-0.60.5-0.2-0.3
Latency to leave start box in cocaine runway, F0.10.10.3-0.1-0.20.00.20.00.00.1-0.6-0.40.2-0.5-0.1
Latency to leave start box in cocaine runway, M0.00.00.1-0.2-0.1-0.30.1-0.3-0.20.2-0.1-0.00.20.3-0.1
Std. dev. time between licks in bursts0.10.10.80.20.5-0.30.1-0.2-0.2-0.30.9-0.0-0.4-0.00.4
Total sessions with >9 infusions1.82.03.41.41.1-1.51.6-1.5-1.5-1.30.8-1.81.61.1-1.4
Short access day 1 total inactive lever presses4.14.55.32.02.1-2.12.2-2.3-2.3-2.11.7-2.32.31.8-2.2
Short access day 10 total inactive lever presses3.84.25.52.12.3-2.12.1-2.2-2.2-2.12.2-2.01.81.5-1.7
Short access day 1 total infusions3.03.15.81.91.3-1.82.0-1.8-1.8-1.80.6-2.42.21.1-1.7
Short access day 10 total infusions1.61.84.61.40.6-1.41.6-1.4-1.4-0.9-0.2-2.21.90.7-1.4
Short access total infusions1.41.63.61.30.8-1.31.5-1.3-1.3-1.10.2-1.91.60.8-1.2
Short access day 1 locomotion2.62.85.01.81.3-1.81.9-1.8-1.8-1.60.8-2.22.01.1-1.5
Short access day 10 total locomotion1.82.04.41.51.0-1.31.6-1.5-1.5-1.20.5-2.11.80.8-1.4
Short access total locomotion1.41.53.61.30.9-1.21.4-1.3-1.3-1.10.4-1.91.50.6-1.1
One hour access (0.3 mA shock)12.114.116.34.03.6-3.83.8-3.7-3.7-3.73.1-3.73.94.0-3.9
Compulsive drug intake3.03.15.2-1.5-1.31.8-1.81.71.71.6-0.71.9-2.3-2.12.2
One hour access (shock baseline)10.912.617.03.63.2-3.63.6-3.5-3.5-3.32.5-3.44.04.1-4.0
Social response proportion0.91.01.3-1.1-1.11.0-1.11.01.00.8-1.11.1-0.9-0.70.9
Social responses0.20.30.6-0.6-0.40.5-0.60.40.50.4-0.10.8-0.7-0.20.7
Social time0.40.50.9-0.6-0.60.9-0.80.80.60.5-0.10.7-1.0-0.40.9
Soleus weight4.412.815.13.83.5-3.73.7-3.7-3.7-3.93.2-3.53.53.4-3.3
Bone: stiffness2.84.48.8-2.2-2.72.2-2.12.12.12.1-3.01.6-1.4-1.91.5
Tibialis anterior weight11.439.245.0-6.6-6.36.6-6.66.76.76.6-5.26.4-6.2-4.95.9
Time to tail flick, vehicle, before self-admin0.50.51.3-0.6-1.00.7-0.60.70.80.7-1.10.4-0.4-0.60.7
Time to tail flick, vehicle, after self-admin1.51.62.7-1.1-1.51.3-1.11.31.21.0-1.40.6-1.2-1.61.6
Time to tail flick, test, before self-admin0.70.72.00.90.5-0.81.0-0.8-0.8-1.00.1-1.41.00.1-0.5
Time to tail flick, test, after self-admin0.00.00.1-0.1-0.10.2-0.20.20.1-0.10.10.2-0.20.10.1
Delta time to tail flick, vehicle, before/after SA0.50.51.0-0.7-0.70.7-0.60.70.60.4-0.70.4-0.7-1.00.9
Delta time to tail flick, test, before/after SA1.41.23.1-1.2-0.71.2-1.31.21.11.1-0.11.8-1.4-0.20.9
Tibia length1.02.84.2-2.1-1.91.9-1.91.81.82.0-1.72.0-1.2-0.10.6
Ambulatory time before self-admin0.40.41.0-0.7-0.80.7-0.70.70.80.6-1.00.7-0.2-0.10.1
Ambulatory time after self-admin0.10.10.40.10.0-0.30.2-0.3-0.3-0.2-0.4-0.20.60.3-0.7
Bone: tissue strength0.00.00.2-0.2-0.20.1-0.20.20.20.1-0.40.20.10.0-0.2
Total heroin consumption6.37.48.5-2.8-2.82.8-2.82.82.82.9-2.62.6-2.6-2.72.5
Bone: trabecular number0.50.72.7-0.9-1.20.7-0.70.70.60.9-1.60.4-0.1-0.70.3
Bone: trabecular spacing0.20.30.80.60.7-0.50.5-0.5-0.4-0.60.9-0.40.10.0-0.0
Bone: trabecular thickness0.50.61.10.60.5-0.90.9-0.9-1.0-0.70.1-1.11.10.4-0.9
Bone: trabecular tissue density3.95.56.32.42.4-2.42.3-2.4-2.4-2.52.2-2.02.22.5-2.4
Water consumed over 24 hours0.91.01.4-0.9-0.71.1-1.01.11.11.0-0.51.1-1.2-1.21.1
Number of responses in last shaping day1.41.52.31.31.4-1.21.3-1.3-1.3-1.11.5-1.20.91.1-1.0