Hub : Genes

Sptbn2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Sptbn2 0.06 0.03 9.3e-11 0.04 0.07 0.06 0.06 9.3e-07 5.6e-11 4.0e-10 7.2e-10
2 BLA mRNA stability Sptbn2 0.14 0.08 1.6e-06 0.09 0.11 0.09 0.1 1.2e-05 3.1e-06 1.3e-05 5.7e-06
3 IC mRNA stability Sptbn2 0.13 0.09 2.2e-04 0.04 0.06 0.06 0.05 7.1e-03 1.7e-03 2.2e-03 3.5e-03
4 PL mRNA stability Sptbn2 0.15 0.09 5.6e-17 0.16 0.16 0.15 0.16 5.1e-17 3.5e-17 6.6e-16 7.3e-17
5 Brain gene expression Sptbn2 0.14 0.1 1.4e-09 0.11 0.1 0.1 0.1 2.2e-10 1.7e-09 6.7e-10 5.9e-10
6 Brain mRNA stability Sptbn2 0.22 0.1 0.0e+00 0.25 0.26 0.26 0.26 2.8e-23 1.5e-24 4.4e-24 4.9e-24
7 PL intron excision ratio chr1_211470463_211470656 0.09 0.06 1.1e-10 0.1 0.11 0.1 0.1 5.2e-11 1.0e-11 1.8e-11 1.9e-11
8 IL mRNA stability Sptbn2 0.37 0.19 3.3e-06 0.16 0.12 0.16 0.08 1.2e-04 6.6e-04 1.3e-04 6.7e-03
9 PL intron excision ratio chr1_211470339_211470413 0.12 0.07 1.1e-13 0.14 0.13 0.14 0.14 1.6e-15 1.8e-14 6.1e-15 5.9e-15
10 BLA intron excision ratio chr1_211470339_211470413 0.29 0.16 4.5e-13 0.21 0.21 0.2 0.21 1.6e-11 1.7e-11 1.3e-10 2.6e-11
11 BLA intron excision ratio chr1_211470463_211470656 0.27 0.17 3.3e-11 0.2 0.18 0.17 0.18 4.8e-11 5.0e-10 4.0e-09 8.0e-10
12 NAcc intron excision ratio chr1_211470339_211470413 0.03 0.02 2.4e-05 0.04 0.03 0.03 0.03 4.7e-06 9.0e-06 2.1e-05 1.0e-05
13 PL gene expression Sptbn2 0.02 0.02 9.3e-03 0.01 0.01 0.01 0.01 1.0e-02 3.4e-02 5.3e-02 2.9e-02
14 OFC mRNA stability Sptbn2 0.2 0.11 1.2e-04 0.13 0.12 0.12 0.03 4.7e-04 7.7e-04 8.9e-04 8.5e-02
15 Brain intron excision ratio chr1_211470339_211470413 0.16 0.08 0.0e+00 0.19 0.2 0.2 0.2 1.4e-17 2.2e-18 3.8e-18 2.9e-18
16 NAcc intron excision ratio chr1_211470463_211470656 0.02 0.01 2.5e-03 0.01 0.02 0.01 0.01 2.7e-03 1.1e-03 1.8e-02 2.7e-03
17 Brain intron excision ratio chr1_211470463_211470656 0.12 0.06 4.5e-13 0.14 0.14 0.14 0.14 4.7e-13 2.1e-13 3.2e-13 2.3e-13
18 Liver gene expression Sptbn2 0.11 0.07 1.9e-04 0.02 0.02 0.01 0.01 6.6e-03 3.6e-03 2.5e-02 7.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.91.63.90.10.70.81.01.61.2-1.3-0.9-0.9-1.31.3-1.31.1-1.11.6-1.5-1.62.0
Area under the delay curve0.50.81.50.60.90.80.81.20.9-0.9-0.5-0.5-0.80.8-0.81.2-1.21.0-1.0-1.00.5
BMI with tail0.41.35.1-1.00.00.20.51.30.9-1.0-0.4-0.4-1.21.2-1.21.1-1.11.6-1.5-1.62.3
BMI without tail0.00.31.0-1.0-0.3-0.3-0.20.20.1-0.20.20.2-0.30.3-0.30.9-1.00.6-0.6-0.60.5
Body weight0.72.99.2-3.0-2.3-2.2-2.0-1.4-1.71.62.12.11.4-1.41.4-1.41.2-1.11.11.1-0.2
Weight adjusted by age0.61.92.9-1.7-1.6-1.5-1.5-1.3-1.41.41.51.51.3-1.31.3-1.51.5-1.21.31.2-0.6
Bone surface0.30.64.2-1.8-1.1-0.7-0.40.4-0.20.00.30.3-0.20.2-0.2-0.70.80.4-0.2-0.42.1
Bone volume0.40.74.7-0.6-0.10.20.41.20.6-0.7-0.4-0.4-0.90.9-0.90.1-0.11.0-0.9-1.12.2
Breakpoint value in progressive ratio session0.81.43.6-1.9-1.7-1.4-1.3-0.8-1.21.11.01.01.0-1.01.0-1.41.4-0.91.00.90.2
Number of licking bursts0.00.10.3-0.6-0.4-0.3-0.30.1-0.30.20.30.30.4-0.40.4-0.40.4-0.10.20.10.3
Context. condit. distance diff. score0.91.12.21.51.31.21.10.91.1-1.0-1.2-1.2-0.80.8-0.81.3-1.30.9-0.9-0.80.2
Locomotion velocity, session 10.40.41.0-0.3-0.4-0.5-0.6-0.5-0.60.60.90.90.7-0.70.7-0.50.5-0.70.60.7-1.0
Locomotion distance, session 10.20.20.5-0.20.30.20.30.70.4-0.5-0.0-0.0-0.30.3-0.30.6-0.60.7-0.7-0.70.7
Locomotion velocity, session 20.91.12.6-1.6-1.3-1.3-1.2-0.9-1.11.01.31.30.9-0.90.9-0.90.9-0.80.80.8-0.3
Locomotion distance, session 20.10.10.4-0.7-0.3-0.4-0.30.0-0.10.10.60.60.1-0.10.10.2-0.10.1-0.1-0.1-0.0
Locomotion velocity, session 30.50.50.70.50.70.70.70.80.7-0.8-0.5-0.5-0.80.8-0.80.8-0.80.8-0.8-0.80.6
Locomotion distance, session 30.00.00.00.00.10.00.00.10.1-0.10.10.10.1-0.10.10.1-0.10.1-0.1-0.1-0.0
Stereotopy head waving bouts, day 31.11.32.51.11.31.11.10.91.2-1.1-0.9-0.9-1.11.1-1.11.6-1.61.1-1.2-1.10.3
Stereotopy head waving duration, day 31.61.92.61.41.51.41.41.21.4-1.4-1.3-1.3-1.51.5-1.51.6-1.61.3-1.4-1.30.7
Locomotion velocity, session 70.80.91.50.70.90.80.80.80.9-0.9-1.0-1.0-0.90.9-0.91.2-1.21.0-1.0-1.00.7
Locomotion distance, session 70.10.10.5-0.10.2-0.0-0.0-0.10.1-0.00.10.1-0.00.0-0.00.7-0.70.1-0.2-0.1-0.5
Stereotopy head waving bouts, day 71.01.22.90.60.70.91.01.21.0-1.1-1.1-1.1-1.21.2-1.20.6-0.61.1-1.1-1.11.7
Stereotopy head waving duration, day 70.40.52.7-0.30.00.30.40.70.5-0.6-0.6-0.6-0.80.8-0.80.2-0.20.7-0.7-0.81.6
Locomotion velocity, session 81.11.31.7-1.2-1.1-1.2-1.2-1.1-1.11.11.31.31.1-1.11.1-1.01.0-1.01.01.0-0.9
Locomotion distance, session 80.30.40.60.70.80.70.70.80.7-0.7-0.6-0.6-0.50.5-0.50.8-0.80.7-0.7-0.70.4
Degree of sensitization distance0.10.10.50.10.30.20.20.20.3-0.3-0.3-0.3-0.40.4-0.40.7-0.70.4-0.5-0.40.1
Degree of sensitization stereotypy0.20.21.9-0.3-0.20.10.20.40.2-0.3-0.4-0.4-0.50.5-0.5-0.30.30.3-0.3-0.41.4
Conditioned locomotion2.32.73.2-1.8-1.7-1.8-1.7-1.8-1.71.71.61.61.8-1.81.8-1.31.3-1.61.51.6-1.4
Cocaine response after cond. corrected0.20.30.91.00.80.70.60.30.6-0.5-0.6-0.6-0.30.3-0.30.7-0.70.4-0.4-0.3-0.3
Cocaine response after cond. not corrected0.30.40.90.90.80.80.70.60.7-0.6-0.7-0.7-0.50.5-0.50.7-0.70.6-0.6-0.50.2
Cocaine response before conditioning0.10.10.8-0.6-0.5-0.3-0.20.2-0.20.10.10.1-0.10.1-0.1-0.60.60.00.1-0.10.9
Saline control response1.21.74.0-2.0-1.6-1.6-1.5-0.9-1.31.31.51.51.1-1.11.1-1.31.3-0.91.00.9-0.3
Bone: connectivity density0.30.42.4-1.0-0.3-0.20.10.70.3-0.4-0.1-0.1-0.50.5-0.50.4-0.40.8-0.8-0.91.5
Bone: cortical apparent density0.50.80.9-0.7-0.8-0.8-0.9-1.0-0.90.90.80.81.0-1.01.0-0.80.8-0.90.90.9-0.9
Bone: cortical area0.61.01.9-1.2-1.2-1.1-1.0-0.7-1.11.01.01.00.9-0.90.9-1.41.4-1.01.00.9-0.2
Bone: cortical porosity0.20.20.40.10.30.30.40.60.4-0.5-0.1-0.1-0.60.6-0.60.6-0.60.6-0.6-0.60.4
Bone: cortical porosity0.00.00.1-0.3-0.0-0.1-0.00.10.1-0.10.20.2-0.20.2-0.20.3-0.30.2-0.2-0.20.1
Bone: cortical thickness5.69.410.5-3.1-3.2-3.2-3.2-3.0-3.23.23.13.13.0-3.03.0-3.03.0-3.13.13.1-2.3
Bone: cortical thickness2.73.34.7-1.6-1.6-1.8-1.9-1.9-1.81.92.02.01.9-1.91.9-1.21.2-1.81.81.8-2.2
Bone: cortical tissue density0.71.11.3-0.9-1.0-1.0-1.0-1.1-1.01.11.01.01.1-1.11.1-0.90.9-1.11.11.1-1.0
Condit. Reinf. active minus inactive responses0.10.10.4-0.4-0.2-0.1-0.00.40.0-0.10.20.2-0.20.2-0.2-0.20.20.2-0.1-0.20.6
Condit. Reinf. active-inactive response ratio0.10.10.6-0.1-0.00.10.10.40.2-0.2-0.1-0.1-0.40.4-0.4-0.20.20.3-0.2-0.30.7
Condit. Reinf. active responses0.00.00.2-0.3-0.2-0.1-0.00.3-0.0-0.00.20.2-0.00.0-0.0-0.20.20.1-0.1-0.10.5
Condit. Reinf. inactive responses0.00.00.10.10.20.20.20.30.2-0.2-0.1-0.1-0.00.0-0.00.2-0.20.2-0.2-0.20.1
Incentive salience index mean0.00.10.3-0.5-0.2-0.2-0.10.3-0.0-0.00.20.2-0.00.0-0.0-0.10.10.2-0.1-0.20.5
Condit. Reinf. lever presses0.10.20.5-0.7-0.6-0.5-0.4-0.1-0.40.30.40.40.4-0.40.4-0.70.7-0.30.30.20.3
Condit. Reinf. active minus inactive responses1.01.63.80.90.91.21.31.61.2-1.3-1.2-1.2-1.41.4-1.40.6-0.61.3-1.2-1.32.0
Condit. Reinf. active-inactive response ratio1.32.13.91.41.21.51.51.71.4-1.5-1.5-1.5-1.61.6-1.60.6-0.61.4-1.3-1.42.0
Condit. Reinf. active responses1.11.63.80.50.81.01.11.61.2-1.3-1.1-1.1-1.51.5-1.50.9-0.91.4-1.3-1.52.0
Condit. Reinf. inactive responses0.20.30.8-0.30.20.10.20.40.4-0.4-0.1-0.1-0.50.5-0.50.9-0.90.6-0.7-0.70.5
Condit. Reinf. lever presses0.20.31.5-1.1-0.8-0.6-0.40.2-0.30.20.40.4-0.30.3-0.3-0.70.70.00.1-0.11.2
Condit. Reinf. lever reinforcers received0.81.13.30.20.50.70.91.30.9-1.0-0.8-0.8-1.21.2-1.20.6-0.61.2-1.1-1.21.8
Conditioned reinforcement - actives0.00.10.3-0.0-0.2-0.1-0.1-0.1-0.20.1-0.1-0.10.1-0.10.1-0.50.6-0.20.30.20.2
Conditioned reinforcement - inactives0.92.43.71.91.61.81.71.71.6-1.6-1.7-1.7-1.61.6-1.61.0-1.01.3-1.3-1.31.5
Conditioned locomotion2.94.39.83.12.62.52.32.02.1-2.0-2.1-2.1-2.02.0-2.01.8-1.71.6-1.6-1.60.8
Patch foraging indifference point 0 sec0.20.61.10.70.70.70.81.10.8-0.8-0.7-0.7-0.90.9-0.90.4-0.60.8-0.8-0.80.8
Patch foraging indifference point AUC1.02.33.7-1.9-1.9-1.7-1.6-1.7-1.61.51.31.31.4-1.41.4-1.61.8-1.41.41.4-0.4
Delay disc. indifference point, 0s delay1.21.43.11.11.41.11.11.11.2-1.1-0.7-0.7-1.21.2-1.21.8-1.81.2-1.3-1.20.2
Delay disc. indifference point, 16s delay1.21.72.31.21.31.41.41.51.4-1.4-1.3-1.3-1.31.3-1.31.1-1.11.4-1.3-1.41.4
Delay disc. indifference point, 2s delay0.60.61.20.70.80.80.81.10.8-0.8-0.6-0.6-0.90.9-0.90.8-0.80.8-0.8-0.80.7
Delay disc. indifference point, 24s delay0.10.21.0-0.0-0.1-0.3-0.3-0.1-0.30.40.50.50.5-0.50.50.1-0.1-0.40.30.4-1.0
Delay disc. indifference point, 4s delay0.50.51.60.50.80.60.60.60.7-0.6-0.3-0.3-0.70.7-0.71.3-1.30.7-0.8-0.7-0.1
Delay disc. indifference point, 8s delay0.20.31.00.40.60.40.40.80.5-0.5-0.2-0.2-0.40.4-0.41.0-1.00.6-0.6-0.6-0.1
Indifference point function ln k1.44.310.63.32.92.52.32.02.1-2.0-1.8-1.8-1.81.8-1.82.3-2.41.6-1.7-1.5-0.2
Indifference point function log k1.44.310.63.32.92.52.32.02.1-2.0-1.8-1.8-1.81.8-1.82.3-2.41.6-1.7-1.5-0.2
Patch foraging total patch changes 0 sec0.00.00.20.30.30.20.20.40.2-0.2-0.1-0.1-0.20.2-0.20.1-0.20.2-0.2-0.20.0
Patch foraging total patch changes 12 sec1.41.95.0-2.2-1.9-1.7-1.6-1.3-1.41.41.21.21.2-1.21.2-1.21.3-1.11.11.0-0.3
Patch foraging total patch changes 18 sec0.00.10.4-0.7-0.5-0.4-0.3-0.2-0.20.20.10.10.0-0.00.0-0.40.2-0.00.00.00.4
Patch foraging total patch changes 24 sec0.62.02.9-1.7-1.6-1.6-1.5-1.4-1.51.41.31.31.4-1.41.4-1.41.4-1.31.31.3-0.8
Patch foraging total patch changes 6 sec0.20.31.3-1.2-0.9-0.8-0.7-0.5-0.50.50.50.50.3-0.30.3-0.50.5-0.30.30.30.3
Patch foraging time to switch 0 sec0.10.32.2-1.0-0.4-0.20.00.50.2-0.3-0.1-0.1-0.40.4-0.40.0-0.20.7-0.6-0.71.5
Patch foraging water rate 0 sec0.10.53.51.91.10.90.70.30.4-0.3-0.6-0.6-0.10.1-0.10.3-0.2-0.10.10.2-1.0
Patch foraging water rate 12 sec0.41.78.22.92.21.61.30.71.0-0.9-1.0-1.0-0.60.6-0.61.5-1.40.4-0.5-0.3-1.7
Patch foraging water rate 18 sec0.30.72.61.61.31.00.80.60.7-0.6-0.6-0.6-0.50.5-0.51.1-1.00.4-0.4-0.3-0.8
Patch foraging water rate 24 sec0.40.53.21.81.20.90.70.40.4-0.3-0.6-0.6-0.10.1-0.10.9-0.6-0.10.00.1-1.2
Patch foraging water rate 6 sec0.30.42.81.71.10.70.50.10.2-0.1-0.0-0.0-0.00.0-0.00.4-0.4-0.30.20.3-1.6
Seeking ratio, delayed vs. immediate footshock0.60.91.80.60.90.80.91.31.0-1.0-0.6-0.6-0.90.9-0.91.0-1.11.1-1.1-1.10.9
Distance traveled before self-admin0.10.21.1-0.2-0.10.10.20.70.2-0.3-0.3-0.3-0.40.4-0.4-0.20.20.4-0.3-0.41.0
Distance traveled after self-admin0.00.10.3-0.2-0.2-0.1-0.10.2-0.0-0.0-0.0-0.0-0.10.1-0.1-0.40.40.00.0-0.10.6
Extensor digitorum longus weight4.819.333.5-5.8-5.2-5.1-4.8-4.0-4.54.44.84.84.1-4.14.1-4.24.3-3.83.93.8-2.1
Bone: elastic displacement0.91.13.3-0.1-0.5-0.7-0.9-1.1-1.01.00.90.91.2-1.21.2-0.70.7-1.21.21.3-1.8
Bone: elastic work3.24.25.4-1.8-1.9-2.0-2.1-2.1-2.12.12.02.02.3-2.32.3-1.71.7-2.02.02.0-2.0
Bone: endosteal estimation2.25.36.62.22.32.42.42.62.4-2.4-2.2-2.2-2.42.4-2.42.1-2.12.4-2.4-2.42.1
Bone: endosteal perimeter3.68.911.72.62.83.03.13.43.0-3.1-2.9-2.9-3.13.1-3.12.2-2.23.1-3.0-3.13.4
Epididymis fat weight1.67.814.43.83.23.33.12.82.8-2.8-3.2-3.2-2.72.7-2.72.3-2.32.3-2.3-2.31.7
Delta time in closed arm before/after self-admin1.11.02.7-0.9-0.8-1.0-1.1-1.3-0.91.01.01.01.2-1.21.2-0.10.1-1.00.81.0-1.7
Delta time in open arm before/after self-admin0.10.10.7-0.3-0.4-0.1-0.1-0.1-0.10.1-0.2-0.2-0.00.0-0.0-0.60.6-0.10.20.10.8
Diff in mean of infusions in LGA sessions0.40.81.2-1.1-1.1-1.0-0.9-0.9-0.90.90.50.51.0-1.01.0-1.01.0-0.90.90.8-0.3
Delay discount exponential model param0.40.51.1-0.4-0.7-0.6-0.6-1.0-0.70.70.30.30.7-0.70.7-1.01.0-0.80.80.8-0.3
Extinction: sum of active levers before priming0.20.31.7-1.3-1.0-0.8-0.6-0.2-0.50.40.40.40.4-0.40.4-0.70.7-0.20.30.10.7
Active lever presses in extinction session 61.81.83.4-1.8-1.7-1.5-1.4-1.1-1.31.21.21.21.2-1.21.2-1.81.8-1.11.21.10.1
Bone: final force0.91.53.0-1.7-1.5-1.4-1.3-0.8-1.21.11.31.31.2-1.21.2-1.31.3-1.01.00.9-0.1
Bone: final moment0.81.32.7-1.6-1.4-1.3-1.2-0.8-1.11.11.31.31.1-1.11.1-1.21.2-0.90.90.9-0.1
Food consumed during 24 hour testing period0.10.20.7-0.2-0.4-0.3-0.3-0.2-0.40.40.20.20.2-0.20.2-0.80.8-0.50.50.50.1
Glucose4.36.97.62.62.82.72.72.72.7-2.7-2.5-2.5-2.72.7-2.72.6-2.52.7-2.7-2.62.0
Heart weight2.84.57.11.82.22.02.12.12.2-2.1-1.8-1.8-2.12.1-2.12.6-2.72.2-2.3-2.21.2
Delay discount hyperbolic model param0.50.61.2-0.5-0.8-0.6-0.7-1.1-0.70.70.40.40.7-0.70.7-1.11.1-0.90.90.8-0.4
Intermittent access intake day 1-15 change0.10.41.21.10.70.80.80.50.6-0.6-0.8-0.8-0.70.7-0.70.1-0.00.4-0.3-0.40.5
Intermittent access intake escalation0.00.20.80.90.50.60.60.30.4-0.4-0.7-0.7-0.50.5-0.5-0.20.20.2-0.1-0.20.4
Intermittent access intake escalation 20.20.30.91.00.50.70.60.40.4-0.4-0.7-0.7-0.50.5-0.5-0.20.20.2-0.1-0.20.4
Intermitt. access day 1 inactive lever presses0.00.10.30.30.10.30.30.30.2-0.2-0.3-0.3-0.30.3-0.3-0.00.00.2-0.1-0.20.5
Intermitt. access day 15 inactive lever presses0.42.12.91.51.31.51.51.51.5-1.5-1.5-1.5-1.61.6-1.60.9-0.91.4-1.3-1.41.7
Intermitt. access escalation Index1.03.35.32.32.22.01.91.61.8-1.8-1.7-1.7-1.71.7-1.72.1-2.21.6-1.7-1.60.4
Intermittent access day 1 total infusions2.88.49.62.52.82.92.93.12.9-3.0-2.8-2.8-2.92.9-2.93.1-3.03.0-3.0-3.02.6
Intermittent access day 15 total infusions2.56.07.62.82.52.72.62.62.5-2.5-2.7-2.7-2.52.5-2.52.0-2.02.3-2.2-2.32.1
Intermittent access terminal intake (last 3 days)3.86.77.92.72.52.72.72.72.6-2.6-2.8-2.8-2.72.7-2.72.2-2.12.4-2.4-2.52.5
Intermittent access total infusions5.56.57.52.42.52.62.62.72.6-2.6-2.6-2.6-2.62.6-2.62.4-2.42.5-2.5-2.52.4
Intermittent access day 1 locomotion2.85.25.92.02.22.32.32.42.3-2.3-2.1-2.1-2.32.3-2.32.4-2.42.3-2.3-2.32.0
Intermittent access day 15 total locomotion1.66.37.42.62.52.72.72.72.5-2.6-2.6-2.6-2.62.6-2.62.0-1.92.4-2.3-2.42.4
Intermittent access total locomotion9.511.413.33.43.43.53.53.73.4-3.5-3.4-3.4-3.63.6-3.63.0-2.93.3-3.2-3.33.2
Intermittent access standard deviation0.10.41.11.00.80.80.70.50.6-0.6-0.7-0.7-0.60.6-0.60.5-0.40.4-0.4-0.40.2
Left kidney weight0.32.14.12.01.81.61.61.21.4-1.3-1.6-1.6-1.31.3-1.31.6-1.81.1-1.2-1.10.4
Right kidney weight0.10.41.61.30.90.80.70.50.5-0.4-0.6-0.6-0.40.4-0.40.6-0.70.2-0.2-0.2-0.3
Cocaine induced anxiety0.00.00.2-0.1-0.10.00.00.10.0-0.1-0.0-0.0-0.10.1-0.1-0.30.20.00.0-0.00.5
Post-drug Anxiety0.30.30.7-0.8-0.8-0.6-0.6-0.4-0.60.50.50.50.5-0.50.5-0.90.8-0.50.50.50.1
Baseline Anxiety0.30.50.6-0.6-0.6-0.7-0.7-0.8-0.70.80.60.60.8-0.80.8-0.60.6-0.70.70.7-0.8
Tail length0.94.65.8-1.9-2.0-2.2-2.2-2.4-2.22.22.32.32.1-2.12.1-1.61.4-2.22.22.2-2.4
Length with tail2.29.811.6-3.4-3.3-3.4-3.3-3.3-3.23.23.43.43.0-3.03.0-2.92.7-3.03.03.0-2.5
Length without tail1.47.49.1-3.0-2.9-2.9-2.9-2.7-2.82.83.03.02.7-2.72.7-2.62.5-2.62.62.6-2.0
Times rat made contact with spout0.10.10.4-0.6-0.3-0.4-0.3-0.2-0.20.20.40.40.2-0.20.20.00.0-0.00.00.0-0.1
Lifetime Intake3.94.85.32.02.12.22.22.32.2-2.2-2.2-2.2-2.22.2-2.22.3-2.22.2-2.2-2.22.0
Liver weight, left0.10.21.60.70.50.20.1-0.30.00.1-0.0-0.00.3-0.30.30.8-0.6-0.30.20.3-1.2
Liver weight, right0.40.82.41.51.41.00.90.70.8-0.7-0.5-0.5-0.40.4-0.41.3-1.30.5-0.7-0.5-0.9
Locomotor activity0.20.22.11.00.70.30.20.00.10.00.20.20.2-0.20.20.0-0.4-0.20.20.3-1.4
Locomotor testing distance0.10.32.71.30.90.50.30.10.2-0.10.20.20.2-0.20.20.2-0.6-0.20.10.2-1.6
Locomotor testing rearing0.31.12.91.71.61.31.20.91.1-1.0-0.7-0.7-0.80.8-0.81.1-1.50.9-1.0-0.8-0.5
Locomotion in novel chamber3.04.17.72.82.42.42.22.12.1-2.0-2.1-2.1-2.02.0-2.01.8-1.71.7-1.7-1.71.0
Locomotion in novel chamber post-restriction0.82.54.52.11.91.81.81.51.6-1.6-1.8-1.8-1.51.5-1.51.4-1.41.4-1.4-1.30.9
Fecal boli incidents, locomotor time 10.00.10.5-0.0-0.20.10.1-0.30.0-0.1-0.3-0.3-0.20.2-0.2-0.30.3-0.00.1-0.00.7
Change in fecal boli incidents, locomotor task0.10.10.50.20.40.20.20.50.3-0.3-0.0-0.0-0.10.1-0.10.7-0.70.4-0.4-0.4-0.3
Time >=10cm from walls, locomotor time 13.44.26.31.61.82.02.02.42.1-2.1-1.9-1.9-2.22.2-2.21.7-1.72.2-2.0-2.22.5
Bouts of movement, locomotor time 10.70.91.8-1.3-1.2-1.0-1.0-0.9-0.90.90.80.80.7-0.70.7-1.31.3-0.80.90.70.1
Total resting periods, locomotor time 10.30.41.0-0.9-0.9-0.6-0.6-0.5-0.60.50.40.40.4-0.40.4-1.01.0-0.40.50.40.5
Rest time, locomotor task time 10.40.71.91.41.01.11.00.90.8-0.8-0.8-0.8-0.80.8-0.80.4-0.40.6-0.5-0.60.5
Distance moved, locomotor task time 10.10.30.6-0.10.30.30.40.60.5-0.5-0.3-0.3-0.70.7-0.70.7-0.70.7-0.7-0.70.8
Vertical activity count, locomotor time 10.00.30.80.70.70.60.50.40.5-0.5-0.5-0.5-0.50.5-0.50.9-0.90.4-0.5-0.4-0.1
Time >=10cm from walls, locomotor time 20.00.10.60.20.10.30.30.60.2-0.3-0.3-0.3-0.30.3-0.3-0.10.10.3-0.2-0.30.8
Bouts of movement, locomotor time 20.00.20.6-0.7-0.6-0.5-0.5-0.5-0.40.30.30.30.3-0.30.3-0.40.4-0.20.30.20.2
Total resting periods, locomotor time 20.00.00.2-0.4-0.3-0.2-0.1-0.2-0.00.0-0.1-0.1-0.00.0-0.0-0.00.00.1-0.1-0.10.4
Rest time, locomotor task time 20.81.42.81.71.51.41.31.01.2-1.1-1.2-1.2-1.01.0-1.01.3-1.30.9-1.0-0.90.3
Distance moved, locomotor task time 20.71.01.7-1.3-1.2-1.1-1.1-0.8-1.01.01.01.00.7-0.70.7-1.31.3-0.90.90.8-0.2
Vertical activity count, locomotor time 20.71.63.0-0.8-1.0-1.2-1.3-1.3-1.31.41.21.21.3-1.31.3-1.11.1-1.41.41.5-1.7
Light reinforcement 10.00.10.20.40.40.30.20.20.2-0.2-0.1-0.10.1-0.10.10.5-0.40.1-0.2-0.1-0.4
Light reinforcement 20.30.71.41.20.91.01.00.90.9-0.9-1.0-1.0-0.80.8-0.80.3-0.30.7-0.6-0.70.9
Bone: marrow area2.35.66.92.22.42.42.52.62.4-2.5-2.2-2.2-2.42.4-2.42.2-2.22.5-2.4-2.42.1
Bone: maximum diameter0.10.11.0-0.0-0.20.10.20.50.1-0.1-0.2-0.2-0.20.2-0.2-0.60.60.10.0-0.11.0
Bone: maximum force0.30.62.7-1.6-1.2-0.9-0.70.1-0.60.40.70.70.3-0.30.3-1.11.1-0.10.30.11.4
Bone: maximum moment0.30.62.4-1.5-1.2-0.9-0.70.1-0.50.40.70.70.3-0.30.3-1.01.0-0.10.20.01.3
Mean time between licks in bursts0.10.61.2-0.7-0.6-0.8-0.8-0.6-0.70.71.01.00.9-0.90.9-0.30.3-0.60.60.7-1.1
Mean num. licks in bursts0.10.20.50.50.50.40.40.00.4-0.4-0.4-0.4-0.50.5-0.50.7-0.70.3-0.4-0.3-0.2
Cd content in liver1.31.42.01.41.31.31.31.21.2-1.2-1.4-1.4-1.11.1-1.10.9-0.91.1-1.1-1.11.0
Co content in liver0.70.84.70.40.0-0.4-0.6-1.1-0.70.80.70.71.0-1.01.0-0.10.1-1.00.91.1-2.2
Cu content in liver0.20.20.30.20.40.30.40.40.4-0.4-0.3-0.3-0.50.5-0.50.6-0.60.5-0.5-0.50.4
Fe content in liver0.50.60.7-0.7-0.7-0.8-0.8-0.8-0.80.80.70.70.8-0.80.8-0.70.7-0.80.80.8-0.8
K content in liver0.00.00.3-0.5-0.3-0.3-0.2-0.0-0.10.10.30.30.1-0.10.10.1-0.10.0-0.0-0.10.1
Mg content in liver0.60.61.00.70.90.80.80.90.8-0.8-0.6-0.6-0.80.8-0.81.0-1.00.9-0.9-0.80.5
Mn content in liver1.41.63.8-2.0-1.8-1.5-1.3-1.0-1.31.11.11.10.9-0.90.9-1.71.7-1.01.10.90.5
Na content in liver0.91.02.0-0.7-1.0-0.9-0.9-0.8-1.01.00.80.81.0-1.01.0-1.41.4-1.01.11.0-0.6
Rb content in liver1.82.23.41.61.71.51.51.31.5-1.5-1.3-1.3-1.41.4-1.41.8-1.81.4-1.5-1.40.6
Se content in liver0.50.61.30.50.50.70.70.80.7-0.7-0.9-0.9-1.01.0-1.00.3-0.30.7-0.6-0.71.1
Sr content in liver2.92.53.2-1.7-1.8-1.7-1.7-1.6-1.61.61.51.51.6-1.61.6-1.81.8-1.61.61.5-0.9
Zn content in liver0.10.10.3-0.5-0.4-0.5-0.4-0.5-0.40.40.40.40.3-0.30.3-0.10.1-0.30.30.3-0.4
Bone: minimum diameter3.26.27.92.02.32.42.52.82.5-2.6-2.4-2.4-2.62.6-2.62.1-2.12.6-2.6-2.62.7
Time in familiar zone, hab. session 10.70.81.20.70.80.90.91.10.9-1.0-0.8-0.8-0.90.9-0.90.7-0.71.0-0.9-1.01.1
Time in novel zone, hab. session 10.20.21.40.0-0.1-0.3-0.4-0.6-0.40.50.40.40.5-0.50.5-0.10.0-0.60.50.6-1.2
Total zone transitions, hab. session 10.20.30.8-0.9-0.7-0.6-0.6-0.2-0.50.40.70.70.3-0.30.3-0.60.6-0.30.30.30.1
Total locomotion distance, hab. session 10.30.50.70.80.80.80.80.80.8-0.8-0.7-0.7-0.60.6-0.60.6-0.60.7-0.7-0.70.5
Locomotion velocity, hab. session 10.10.10.20.30.30.30.30.40.3-0.3-0.2-0.2-0.20.2-0.20.3-0.30.4-0.4-0.40.3
Time in familiar zone, hab. session 20.50.51.3-0.5-0.5-0.7-0.7-0.9-0.70.70.80.80.8-0.80.8-0.30.3-0.80.70.8-1.1
Time in novel zone, hab. session 20.50.51.00.40.50.60.70.80.7-0.7-0.6-0.6-0.90.9-0.90.5-0.50.8-0.8-0.81.0
Total zone transitions, hab. session 21.01.22.9-0.20.50.60.81.31.0-1.1-0.5-0.5-1.21.2-1.21.2-1.11.5-1.4-1.51.7
Total locomotion distance, hab. session 21.21.62.40.81.21.11.21.41.3-1.4-1.0-1.0-1.21.2-1.21.5-1.41.5-1.5-1.51.2
Locomotion velocity, hab. session 21.62.12.91.01.41.31.41.61.5-1.5-1.2-1.2-1.31.3-1.31.5-1.51.7-1.7-1.71.5
Novel to familiar place preference ratio0.10.21.8-0.5-0.4-0.10.10.30.1-0.1-0.4-0.4-0.20.2-0.2-0.50.50.2-0.1-0.31.3
Novelty place preference0.20.32.0-0.1-0.00.30.40.50.4-0.4-0.7-0.7-0.50.5-0.5-0.20.20.5-0.4-0.51.4
Time in novel zone, NPP test0.20.31.5-0.00.00.30.40.50.4-0.4-0.7-0.7-0.50.5-0.5-0.00.00.5-0.4-0.51.2
Total zone transitions, NPP test0.20.31.4-1.2-0.8-0.7-0.6-0.1-0.40.40.80.80.4-0.40.4-0.30.4-0.10.10.10.3
Total locomotion distance, NPP test0.10.10.30.10.30.20.30.50.3-0.30.00.0-0.20.2-0.20.4-0.40.4-0.4-0.40.2
Locomotion velocity, NPP test0.00.10.20.00.20.20.20.40.2-0.30.00.0-0.10.1-0.10.3-0.30.4-0.3-0.40.2
Intraocular pressure0.10.10.50.70.20.40.3-0.10.2-0.1-0.6-0.60.1-0.10.1-0.40.2-0.10.10.10.1
Delta distance traveled before/after self-admin0.20.20.6-0.1-0.2-0.3-0.4-0.5-0.40.40.30.30.5-0.50.5-0.10.1-0.50.40.5-0.8
Delta ambulatory time before/after self-admin0.20.30.8-0.2-0.3-0.4-0.5-0.6-0.50.50.40.40.6-0.60.6-0.20.2-0.60.50.6-0.9
Parametrial fat weight2.76.59.83.12.92.82.72.32.6-2.5-2.8-2.8-2.52.5-2.52.5-2.62.2-2.3-2.21.3
Pavlov. Cond. lever latency0.00.10.20.50.30.30.30.30.2-0.2-0.3-0.3-0.20.2-0.20.2-0.20.2-0.1-0.20.0
Pavlov. Cond. magazine entry latency0.50.62.00.20.40.60.71.10.7-0.8-0.5-0.5-0.90.9-0.90.3-0.30.9-0.8-0.91.4
Pavlov. Cond. change in total contacts0.40.42.20.20.20.50.50.80.5-0.6-0.6-0.6-0.70.7-0.7-0.20.20.6-0.5-0.61.5
Pavlov. Cond. index score0.00.00.3-0.2-0.2-0.1-0.00.1-0.0-0.00.10.1-0.10.1-0.1-0.40.40.00.0-0.00.5
Pavlov. Cond. latency score0.00.00.2-0.1-0.00.10.10.20.1-0.2-0.1-0.1-0.20.2-0.2-0.10.10.2-0.2-0.20.5
Pavlov. Cond. lever contacts0.00.00.0-0.1-0.0-0.00.00.00.1-0.10.00.0-0.10.1-0.10.1-0.10.1-0.1-0.10.1
Pavlov. Cond. magazine entry number0.10.10.60.40.40.20.2-0.10.2-0.2-0.2-0.2-0.10.1-0.10.8-0.80.2-0.2-0.1-0.6
Pavlov. Cond. intertrial magazine entries0.00.00.10.20.10.10.0-0.1-0.10.1-0.2-0.20.0-0.00.0-0.20.2-0.20.10.2-0.2
Pavlov. Cond. lever-magazine prob. diff.0.00.10.4-0.3-0.3-0.1-0.00.2-0.0-0.00.10.1-0.10.1-0.1-0.40.40.1-0.0-0.10.6
Pavlov. Cond. response bias0.10.10.4-0.4-0.4-0.3-0.20.0-0.30.20.30.30.1-0.10.1-0.70.7-0.20.30.20.3
Pavlov. Cond. lever latency0.30.40.80.80.80.70.60.40.6-0.6-0.6-0.6-0.40.4-0.40.9-0.90.5-0.6-0.5-0.2
Pavlov. Cond. magazine entry latency0.60.93.7-1.9-1.5-1.2-1.0-0.4-0.80.71.01.00.6-0.60.6-1.11.1-0.30.50.30.9
Pavlov. Cond. change in total contacts0.10.33.0-0.9-0.7-0.3-0.10.4-0.1-0.10.00.0-0.30.3-0.3-0.70.80.3-0.1-0.31.7
Pavlov. Cond. index score0.40.62.1-1.5-1.2-0.9-0.7-0.3-0.60.50.70.70.3-0.30.3-1.11.1-0.30.40.21.0
Pavlov. Cond. latency score0.40.61.9-1.4-1.2-0.9-0.7-0.3-0.70.50.70.70.3-0.30.3-1.11.1-0.30.50.30.9
Pavlov. Cond. lever contacts0.20.30.6-0.8-0.7-0.6-0.5-0.3-0.50.40.50.50.3-0.30.3-0.80.8-0.40.40.40.4
Pavlov. Cond. magazine entry number1.41.86.32.52.01.71.40.71.2-1.1-1.4-1.4-0.90.9-0.91.7-1.70.7-0.9-0.6-1.0
Pavlov. Cond. intertrial magazine entries0.30.71.61.21.11.00.90.70.8-0.8-0.9-0.9-0.80.8-0.80.8-0.80.7-0.7-0.60.1
Pavlov. Cond. lever-magazine prob. diff.0.50.72.6-1.6-1.3-1.0-0.8-0.4-0.70.60.80.80.4-0.40.4-1.21.2-0.40.50.31.0
Pavlov. Cond. response bias0.30.51.7-1.3-1.1-0.8-0.7-0.2-0.60.50.60.60.3-0.30.3-0.90.9-0.30.40.20.8
Time in closed arm before self-admin0.91.52.41.11.11.21.31.51.2-1.3-1.1-1.1-1.41.4-1.40.7-0.71.3-1.2-1.31.5
Time in closed arm after self-admin0.10.10.10.30.40.30.30.40.3-0.3-0.1-0.1-0.20.2-0.20.3-0.30.3-0.3-0.30.0
Time in open arm before self-admin0.60.74.1-0.2-0.2-0.6-0.7-0.8-0.60.80.90.91.0-1.01.00.2-0.2-0.80.60.8-2.0
Time in open arm after self-admin0.20.30.4-0.5-0.5-0.5-0.5-0.6-0.50.60.40.40.6-0.60.6-0.20.2-0.60.50.6-0.7
Bone: periosteal estimation0.20.51.30.50.50.70.71.00.7-0.7-0.7-0.7-0.80.8-0.80.3-0.30.8-0.7-0.81.1
Bone: periosteal perimeter0.40.83.00.30.50.70.81.20.8-0.9-0.8-0.8-1.01.0-1.00.2-0.21.0-0.8-1.01.7
Bone: post-yield work4.47.519.21.01.72.22.53.22.6-2.8-2.5-2.5-3.13.1-3.11.8-1.83.2-3.0-3.24.4
Progressive ratio test 1 active lever presses0.20.30.60.40.50.50.60.70.6-0.6-0.7-0.7-0.50.5-0.50.6-0.50.6-0.6-0.60.7
Progressive ratio test 1 breakpoint0.20.30.50.30.40.50.50.60.5-0.5-0.7-0.7-0.40.4-0.40.5-0.50.6-0.5-0.60.7
Progressive ratio test 1 inactive lever presses0.10.20.40.20.30.40.40.40.4-0.4-0.4-0.4-0.40.4-0.40.3-0.30.4-0.4-0.40.6
Progressive ratio test 2 active lever presses2.13.03.71.71.71.81.81.91.7-1.8-1.9-1.9-1.71.7-1.71.5-1.51.6-1.6-1.61.7
Progressive ratio test 2 breakpoint2.12.73.41.71.61.71.71.81.6-1.7-1.8-1.8-1.61.6-1.61.4-1.41.6-1.5-1.61.6
Progressive ratio test 2 inactive lever presses2.99.112.03.53.23.33.23.13.1-3.1-3.1-3.1-3.13.1-3.12.8-2.82.8-2.8-2.82.4
Incentive Sensitization - Responses0.30.71.80.40.50.70.81.00.8-0.9-0.7-0.7-1.01.0-1.00.7-0.71.0-0.9-1.01.3
Incentive Sensitization - Breakpoint0.40.91.90.60.70.80.91.10.9-1.0-0.8-0.8-1.11.1-1.10.7-0.81.0-1.0-1.01.4
Sum of active levers in priming session hrs 5-63.43.26.8-1.6-2.0-1.7-1.7-1.6-1.81.71.41.41.7-1.71.7-2.62.6-1.92.01.8-0.5
Progressive ratio0.41.12.5-0.20.50.50.71.11.0-1.0-0.7-0.7-1.21.2-1.21.1-1.21.3-1.3-1.41.6
Food seeking constrained by brief footshock0.20.20.4-0.5-0.5-0.5-0.5-0.6-0.50.50.60.60.4-0.40.4-0.50.4-0.40.40.4-0.5
Seeking ratio, punishment vs. effort0.30.62.70.4-0.0-0.3-0.4-0.8-0.60.70.60.60.9-0.90.9-0.50.5-0.90.90.9-1.7
Retroperitoneal fat weight5.424.344.86.76.05.75.44.75.0-4.8-5.1-5.1-4.74.7-4.75.1-5.24.1-4.3-4.01.9
Reaction time number correct0.31.01.2-0.7-0.9-0.9-0.9-0.9-1.01.01.01.01.0-1.01.0-1.01.1-1.01.11.0-0.8
Reaction time mean minus median0.31.74.2-2.1-1.8-1.5-1.4-1.0-1.31.21.21.21.1-1.11.1-1.91.7-0.91.00.90.4
Reaction time mean minus median AUC0.32.34.1-1.8-1.8-1.6-1.5-1.4-1.51.41.41.41.5-1.51.5-2.01.7-1.31.41.3-0.5
Reaction time num false alarms0.40.72.8-0.1-0.3-0.6-0.7-0.9-0.70.80.70.71.0-1.01.00.20.2-0.90.80.9-1.7
Reaction time num false alarms AUC0.61.32.9-0.8-0.8-1.1-1.2-1.2-1.11.21.21.21.4-1.41.4-0.30.7-1.21.11.2-1.7
Reaction time trials correct on left0.31.01.2-0.7-0.9-0.9-0.9-0.9-1.01.01.01.01.0-1.01.0-1.01.1-1.01.11.0-0.8
Reaction time trials on left0.41.21.6-0.9-1.1-1.1-1.1-1.1-1.11.11.11.11.1-1.11.1-1.21.3-1.21.21.2-0.9
Reaction time mean0.00.00.2-0.1-0.1-0.00.00.20.0-0.10.00.0-0.10.1-0.1-0.40.20.1-0.1-0.10.3
Reaction time mean AUC0.00.10.3-0.00.10.20.20.40.2-0.2-0.2-0.2-0.20.2-0.2-0.20.00.3-0.2-0.30.6
Median of all reaction times0.20.30.40.50.50.60.60.60.6-0.6-0.5-0.5-0.60.6-0.60.3-0.50.6-0.6-0.60.5
Reaction time omissions1.32.03.5-1.9-1.7-1.6-1.5-1.3-1.41.41.31.31.5-1.51.5-1.81.5-1.21.21.2-0.4
Reaction time false alarm rate0.20.31.4-0.1-0.2-0.4-0.5-0.6-0.40.50.50.50.7-0.70.70.4-0.0-0.50.40.5-1.2
Reaction time premature initiation rate2.23.34.6-2.1-1.8-2.0-2.0-1.8-1.81.82.12.12.0-2.02.0-1.21.2-1.61.61.6-1.8
Reaction time premature initiations2.16.58.1-2.7-2.5-2.7-2.7-2.5-2.62.62.82.82.7-2.72.7-2.12.1-2.32.32.4-2.3
Std. dev. reaction times0.20.61.5-1.1-1.0-0.8-0.7-0.5-0.70.60.70.70.6-0.60.6-1.20.9-0.50.60.50.2
Reaction time trials completed0.41.21.6-0.9-1.1-1.1-1.1-1.1-1.11.11.11.11.1-1.11.1-1.21.3-1.21.21.2-0.9
Reaction time trials AUC0.30.91.1-0.7-0.9-0.9-0.9-0.9-1.01.01.01.01.0-1.01.0-1.01.0-1.01.01.0-0.9
Run reversals in cocaine runway, females0.10.10.5-0.40.0-0.2-0.1-0.00.1-0.10.50.5-0.10.1-0.10.7-0.70.2-0.3-0.2-0.2
Run reversals in cocaine runway, males1.41.62.8-0.4-0.9-1.0-1.1-1.5-1.21.31.11.11.3-1.31.3-1.11.2-1.51.51.5-1.7
Latency to leave start box in cocaine runway0.81.12.20.60.80.91.01.21.0-1.1-1.1-1.1-1.11.1-1.10.8-0.81.2-1.1-1.21.5
Latency to leave start box in cocaine runway, F0.50.61.00.50.60.70.70.80.8-0.8-0.8-0.8-0.80.8-0.80.6-0.60.9-0.8-0.91.0
Latency to leave start box in cocaine runway, M0.10.10.5-0.10.00.20.20.30.2-0.3-0.2-0.2-0.30.3-0.30.0-0.00.3-0.2-0.30.7
Std. dev. time between licks in bursts0.61.24.2-0.5-0.5-0.9-1.0-1.1-1.01.01.21.21.4-1.41.4-0.20.2-1.11.01.1-2.0
Total sessions with >9 infusions0.60.81.30.30.60.60.70.90.8-0.9-0.7-0.7-0.90.9-0.91.1-1.01.0-1.0-1.01.0
Short access day 1 total inactive lever presses1.02.03.21.81.71.61.51.31.4-1.4-1.5-1.5-1.41.4-1.41.6-1.71.2-1.3-1.20.6
Short access day 10 total inactive lever presses0.00.10.20.40.30.30.20.10.2-0.2-0.1-0.1-0.20.2-0.20.3-0.40.2-0.2-0.2-0.0
Short access day 1 total infusions1.73.34.31.71.81.81.81.81.8-1.8-1.7-1.7-1.81.8-1.82.1-2.01.8-1.8-1.81.4
Short access day 10 total infusions2.74.55.91.21.71.82.02.32.1-2.2-2.0-2.0-2.22.2-2.22.3-2.22.3-2.3-2.42.4
Short access total infusions1.52.13.30.91.31.31.41.51.4-1.5-1.3-1.3-1.41.4-1.41.8-1.81.6-1.6-1.61.3
Short access day 1 locomotion1.52.52.91.41.51.61.61.61.6-1.6-1.5-1.5-1.61.6-1.61.7-1.61.6-1.6-1.61.4
Short access day 10 total locomotion0.72.83.41.41.61.61.71.81.7-1.7-1.5-1.5-1.81.8-1.81.6-1.61.7-1.7-1.71.7
Short access total locomotion2.03.13.51.51.71.71.81.91.8-1.8-1.6-1.6-1.81.8-1.81.8-1.71.8-1.8-1.81.7
One hour access (0.3 mA shock)4.45.27.42.72.52.52.42.32.3-2.3-2.3-2.3-2.22.2-2.22.3-2.22.1-2.1-2.01.5
Compulsive drug intake3.45.07.1-2.0-2.0-2.3-2.3-2.4-2.22.32.42.42.4-2.42.4-1.61.6-2.22.12.2-2.7
One hour access (shock baseline)3.28.410.63.33.03.23.13.12.9-3.0-3.1-3.1-3.03.0-3.02.5-2.42.7-2.6-2.72.6
Social response proportion0.10.10.5-0.6-0.4-0.2-0.10.1-0.0-0.00.10.10.0-0.00.0-0.30.30.2-0.1-0.20.7
Social responses0.20.30.6-0.7-0.6-0.6-0.6-0.6-0.50.50.60.60.6-0.60.6-0.70.5-0.50.50.5-0.4
Social time0.40.70.9-0.8-0.8-0.8-0.8-0.9-0.80.80.90.90.8-0.80.8-0.70.7-0.80.70.8-0.8
Soleus weight1.23.510.33.22.72.32.11.51.8-1.7-1.9-1.9-1.61.6-1.62.0-2.11.3-1.4-1.2-0.4
Bone: stiffness0.20.32.9-1.1-0.6-0.3-0.10.50.0-0.20.00.0-0.20.2-0.2-0.40.40.4-0.3-0.51.7
Tibialis anterior weight9.432.544.9-6.7-6.5-6.3-6.1-5.4-5.95.85.95.95.5-5.55.5-5.85.8-5.35.45.3-3.2
Time to tail flick, vehicle, before self-admin0.00.10.2-0.10.10.10.10.30.2-0.2-0.0-0.0-0.20.2-0.20.2-0.20.3-0.3-0.30.4
Time to tail flick, vehicle, after self-admin0.10.20.7-0.30.20.10.20.50.4-0.4-0.1-0.1-0.40.4-0.40.8-0.80.6-0.7-0.60.5
Time to tail flick, test, before self-admin2.62.95.21.61.91.71.71.81.8-1.7-1.5-1.5-1.51.5-1.52.3-2.31.8-1.8-1.71.0
Time to tail flick, test, after self-admin0.00.00.2-0.1-0.10.00.00.20.0-0.1-0.1-0.10.0-0.00.0-0.10.10.00.0-0.00.5
Delta time to tail flick, vehicle, before/after SA0.00.10.2-0.4-0.1-0.1-0.00.20.1-0.10.00.0-0.10.1-0.10.4-0.40.3-0.3-0.30.3
Delta time to tail flick, test, before/after SA3.74.67.0-1.8-2.2-2.0-2.1-2.2-2.22.21.81.82.1-2.12.1-2.62.6-2.32.32.2-1.4
Tibia length0.92.55.1-1.7-1.9-1.6-1.5-1.2-1.71.61.21.21.5-1.51.5-2.22.2-1.51.71.5-0.3
Ambulatory time before self-admin0.10.42.6-0.10.10.40.51.00.5-0.6-0.6-0.6-0.70.7-0.7-0.20.20.7-0.6-0.71.6
Ambulatory time after self-admin1.01.53.01.01.01.21.21.51.2-1.3-1.3-1.3-1.41.4-1.40.6-0.61.3-1.2-1.31.7
Bone: tissue strength0.20.20.50.20.30.40.40.60.4-0.4-0.4-0.4-0.40.4-0.40.2-0.20.5-0.4-0.50.7
Total heroin consumption2.32.75.4-2.3-2.1-1.9-1.8-1.4-1.71.61.31.31.6-1.61.6-1.81.8-1.41.41.3-0.4
Bone: trabecular number0.61.14.2-0.20.30.60.81.30.9-1.0-0.8-0.8-1.11.1-1.10.8-0.81.3-1.3-1.42.1
Bone: trabecular spacing0.10.21.40.30.2-0.0-0.2-0.5-0.20.30.30.30.4-0.40.40.2-0.2-0.40.30.4-1.2
Bone: trabecular thickness1.72.33.21.11.31.41.51.81.5-1.6-1.4-1.4-1.61.6-1.61.4-1.41.7-1.6-1.71.7
Bone: trabecular tissue density0.61.14.42.11.51.51.30.91.0-1.0-1.2-1.2-0.90.9-0.90.6-0.60.6-0.6-0.50.0
Water consumed over 24 hours0.30.51.1-1.1-0.9-0.9-0.8-0.5-0.70.70.80.80.7-0.70.7-0.60.6-0.50.60.5-0.2
Number of responses in last shaping day0.10.10.5-0.2-0.2-0.3-0.3-0.5-0.30.40.30.30.5-0.50.50.1-0.1-0.40.30.4-0.7