Adra1a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA isoform ratio XM_063274181.1 0.04 0.03 5.4e-03 0.02 0.02 0 0.02 1.5e-02 1.4e-02 2.6e-01 1.7e-02
2 PL alternative polyA XM_063274182.1 0.04 0.03 6.7e-04 0.02 0.02 0.02 0.02 2.6e-03 3.1e-03 1.2e-03 4.9e-03
3 PL alternative polyA XM_006252109.5 0.04 0.03 3.2e-04 0.02 0.02 0.03 0.02 1.5e-03 1.8e-03 3.5e-04 3.0e-03
4 Brain isoform ratio XM_063274181.1 0.22 0.12 1.0e-15 0.17 0.16 0.17 0.16 2.9e-15 3.2e-15 2.4e-15 4.3e-15
5 Brain gene expression Adra1a 0.33 0.12 0.0e+00 0.32 0.37 0.36 0.36 3.9e-30 8.8e-36 2.3e-34 6.3e-35
6 PL mRNA stability Adra1a 0.17 0.09 0.0e+00 0.14 0.15 0.15 0.16 2.1e-15 1.9e-16 9.7e-16 7.1e-17
7 IC mRNA stability Adra1a 0.12 0.07 2.5e-04 0.09 0.09 0.07 0.09 2.0e-04 2.1e-04 8.6e-04 1.8e-04
8 NAcc alternative polyA XM_006252109.5 0.02 0.01 5.6e-03 0.01 0.01 0.01 0.01 6.7e-03 8.5e-03 8.9e-03 2.4e-02
9 NAcc isoform ratio XM_063274181.1 0.02 0.01 4.9e-03 0.02 0.02 0.01 0.01 1.6e-03 1.5e-03 5.8e-03 1.7e-02
10 PL isoform ratio XM_063274181.1 0.03 0.02 3.2e-03 0.02 0.02 0.01 0.01 4.2e-03 7.0e-03 3.2e-02 9.9e-03
11 pVTA gene expression Adra1a 0.08 0.05 4.6e-06 0.08 0.07 0.06 0.06 3.4e-07 3.6e-06 1.8e-05 8.9e-06
12 Adipose gene expression Adra1a 0.06 0.04 3.2e-05 0.04 0.02 0.03 0.04 2.5e-05 1.5e-03 9.3e-05 2.2e-05
13 Brain mRNA stability Adra1a 0.34 0.13 0.0e+00 0.25 0.28 0.27 0.27 3.5e-23 7.9e-26 1.7e-25 5.8e-25
14 Adipose isoform ratio XM_063274181.1 0.04 0.03 3.4e-04 0.03 0.02 0.02 0.02 6.0e-04 1.2e-03 3.9e-03 1.8e-03
15 OFC gene expression Adra1a 0.23 0.14 3.6e-03 0.14 0.02 0.07 0.07 3.2e-04 1.0e-01 8.1e-03 9.9e-03
16 IC intron excision ratio chr15_45097853_45101519 0.11 0.08 9.4e-04 0.03 0.04 0.01 0.02 1.9e-02 8.9e-03 1.1e-01 4.0e-02
17 Brain isoform ratio XM_006252110.5 0.03 0.02 7.1e-03 0.01 0.01 0.02 0.01 2.3e-02 1.4e-02 2.7e-03 1.6e-02
18 IC gene expression Adra1a 0.16 0.1 1.3e-04 0.08 0.09 0.05 0.08 3.1e-04 1.1e-04 4.1e-03 3.7e-04
19 BLA gene expression Adra1a 0.32 0.13 2.0e-12 0.18 0.19 0.18 0.19 1.1e-09 2.8e-10 1.0e-09 3.5e-10
20 IC isoform ratio XM_006252107.5 0.07 0.06 7.9e-03 0.04 0.05 0.03 0.03 7.4e-03 3.5e-03 2.7e-02 2.7e-02
21 NAcc gene expression Adra1a 0.02 0.02 8.3e-04 0 0.02 0.01 0.01 1.7e-01 1.4e-03 2.3e-02 3.0e-02
22 IL gene expression Adra1a 0.49 0.17 5.0e-07 0.08 0.16 0.13 0.12 6.3e-03 1.2e-04 4.8e-04 7.8e-04
23 NAcc mRNA stability Adra1a 0.12 0.07 1.2e-13 0.09 0.09 0.09 0.09 8.7e-14 4.1e-14 1.0e-13 7.9e-14
24 PL intron excision ratio chr15_45097853_45101519 0.03 0.02 5.5e-03 0.02 0 -0 0 3.5e-03 8.6e-02 4.0e-01 8.6e-02
25 PL isoform ratio XM_006252107.5 0.04 0.03 1.2e-03 0.02 0.01 0.01 0.01 1.0e-03 1.5e-02 3.2e-02 1.7e-02
26 PL gene expression Adra1a 0.32 0.16 0.0e+00 0.13 0.22 0.23 0.22 2.9e-14 6.7e-24 1.2e-24 1.4e-23

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.61.02.80.80.3-0.3-1.10.31.01.3-0.30.1-1.1-0.00.11.3-1.10.51.50.9-0.5-0.51.7-1.0-1.21.6-1.4-1.61.0
Area under the delay curve0.10.20.40.5-0.50.6-0.40.60.30.30.70.6-0.4-0.60.60.2-0.1-0.20.00.10.60.6-0.20.60.6-0.20.30.2-0.6
BMI with tail0.20.71.7-1.10.7-0.81.1-1.0-1.1-1.1-0.8-0.81.20.4-0.6-1.11.31.0-1.0-0.0-0.4-0.4-0.8-0.10.1-0.60.70.7-0.2
BMI without tail0.31.53.2-1.31.7-1.70.9-1.6-1.3-0.8-1.7-1.61.11.5-1.8-0.51.01.7-0.4-1.1-1.5-1.5-0.2-1.2-1.00.2-0.2-0.20.8
Body weight0.10.61.90.3-0.90.9-0.00.60.10.20.80.80.0-1.21.0-0.30.6-0.3-0.51.11.01.0-0.71.11.1-0.80.80.6-1.4
Weight adjusted by age0.72.04.70.7-1.81.8-0.11.20.5-0.11.71.4-0.0-1.82.0-0.5-0.1-2.0-0.72.21.71.7-1.01.81.8-1.21.51.4-1.9
Bone surface0.71.35.61.4-0.60.5-1.51.11.51.60.60.9-1.5-0.91.01.5-1.2-0.11.52.40.30.31.5-0.2-0.51.2-1.1-1.20.2
Bone volume0.61.24.21.4-0.60.6-1.51.11.51.60.60.9-1.5-0.80.81.4-1.3-0.31.52.10.30.31.5-0.2-0.51.2-1.1-1.20.3
Breakpoint value in progressive ratio session0.10.30.8-0.4-0.10.00.7-0.1-0.4-0.70.1-0.00.7-0.10.2-0.80.7-0.0-0.70.30.40.4-0.50.40.4-0.70.70.9-0.5
Number of licking bursts0.20.61.0-0.91.0-0.90.7-0.9-0.8-0.6-0.9-1.00.71.0-1.0-0.50.71.0-0.3-0.9-0.8-0.8-0.1-0.7-0.6-0.00.1-0.30.8
Context. condit. distance diff. score5.66.813.4-2.53.7-3.61.5-3.1-2.2-1.5-3.5-3.31.63.5-3.6-0.51.13.4-0.1-2.8-3.4-3.40.4-3.1-2.81.2-1.1-1.13.0
Locomotion velocity, session 10.30.30.90.4-0.80.8-0.10.60.4-0.10.70.7-0.1-0.70.7-0.2-0.3-1.0-0.10.70.80.8-0.10.60.5-0.40.40.6-0.5
Locomotion distance, session 11.72.24.31.9-2.02.0-1.42.01.61.21.92.0-1.4-2.12.00.9-1.2-1.80.80.61.71.70.41.41.1-0.0-0.10.3-1.1
Locomotion velocity, session 21.11.43.01.1-1.61.6-0.71.41.00.61.51.5-0.8-1.51.50.3-0.8-1.70.21.71.51.40.01.21.1-0.40.40.6-1.0
Locomotion distance, session 22.33.26.32.1-2.42.3-1.62.32.01.52.22.4-1.7-2.52.51.0-1.5-2.10.91.82.12.00.61.61.2-0.0-0.10.2-1.4
Locomotion velocity, session 30.91.02.7-1.30.8-0.81.4-1.1-1.5-1.6-0.6-0.91.30.9-0.8-1.31.30.6-1.3-0.4-0.4-0.5-1.30.00.3-0.90.91.2-0.1
Locomotion distance, session 30.70.81.5-1.11.1-1.10.9-1.2-1.1-1.0-1.1-1.20.91.2-1.1-0.60.60.9-0.5-0.8-1.0-1.0-0.4-0.7-0.5-0.00.10.20.7
Stereotopy head waving bouts, day 30.50.61.6-0.1-0.60.60.50.3-0.4-0.60.70.40.5-0.60.6-0.90.9-0.4-0.90.00.90.9-0.91.01.0-1.11.11.2-0.9
Stereotopy head waving duration, day 31.11.43.1-0.2-1.01.00.80.4-0.6-1.01.00.60.8-0.90.9-1.31.0-0.9-1.4-0.21.31.3-1.61.61.7-1.81.71.8-1.5
Locomotion velocity, session 77.38.015.4-2.03.9-3.90.8-3.0-1.6-0.8-3.7-3.30.63.6-3.70.50.33.70.9-2.4-3.9-3.91.5-3.8-3.62.4-2.3-2.13.4
Locomotion distance, session 75.16.513.6-1.23.4-3.40.0-2.2-0.70.0-3.2-2.7-0.23.1-3.11.2-0.53.21.7-0.8-3.4-3.52.3-3.7-3.72.8-2.7-2.53.2
Stereotopy head waving bouts, day 71.21.43.30.3-1.41.40.20.90.1-0.21.41.10.2-1.31.3-0.70.6-1.3-1.0-0.31.51.5-1.41.81.8-1.51.41.4-1.6
Stereotopy head waving duration, day 71.41.74.1-0.3-1.11.10.90.3-0.6-1.01.00.61.0-1.01.0-1.41.1-1.1-1.7-0.41.31.3-2.01.82.0-2.01.91.9-1.7
Locomotion velocity, session 80.60.82.3-1.20.9-0.91.1-1.1-1.2-1.2-0.9-1.01.00.8-0.9-1.00.90.7-0.9-1.5-0.7-0.6-0.7-0.3-0.1-0.50.50.60.5
Locomotion distance, session 80.50.71.6-0.31.1-1.1-0.1-0.7-0.30.0-1.0-0.8-0.10.9-0.90.4-0.21.00.6-1.2-1.1-1.10.7-1.1-1.11.0-0.9-0.81.2
Degree of sensitization distance4.24.510.3-0.12.3-2.3-1.0-1.10.31.0-2.1-1.5-1.12.1-2.11.9-1.12.42.2-0.1-2.5-2.52.7-3.0-3.23.0-2.8-2.82.7
Degree of sensitization stereotypy0.70.71.9-0.0-0.80.80.30.4-0.2-0.40.80.60.4-0.80.7-0.70.6-0.8-1.0-0.40.91.0-1.31.31.4-1.21.21.1-1.1
Conditioned locomotion0.91.01.9-1.31.4-1.41.2-1.3-1.2-1.1-1.3-1.31.11.3-1.3-0.80.91.2-0.5-0.5-1.0-1.0-0.1-0.9-0.8-0.10.10.40.8
Cocaine response after cond. corrected2.43.66.7-2.62.2-2.22.4-2.5-2.4-2.4-2.2-2.42.22.2-2.1-1.92.12.1-1.6-1.0-1.6-1.6-0.9-1.3-0.9-0.70.70.91.0
Cocaine response after cond. not corrected1.31.93.8-2.01.6-1.61.9-1.8-1.7-1.8-1.6-1.71.71.6-1.6-1.51.41.3-1.2-0.5-1.1-1.1-0.7-0.9-0.7-0.60.60.80.7
Cocaine response before conditioning2.22.75.02.2-1.91.9-2.12.12.22.01.82.0-1.8-1.71.61.6-2.1-2.11.41.41.41.41.10.90.60.6-0.7-0.7-0.7
Saline control response1.21.63.11.7-1.41.4-1.61.71.61.51.41.6-1.5-1.61.71.3-1.3-1.11.11.41.11.10.80.80.50.5-0.6-0.3-0.9
Bone: connectivity density1.01.54.00.40.9-0.9-0.9-0.20.71.1-0.9-0.5-0.90.7-0.51.3-1.21.01.60.6-1.1-1.12.0-1.7-1.91.9-1.8-1.81.7
Bone: cortical apparent density0.81.32.7-1.31.6-1.61.0-1.5-1.2-0.9-1.6-1.60.81.4-1.4-0.40.61.5-0.3-0.6-1.5-1.5-0.0-1.3-1.10.4-0.4-0.30.8
Bone: cortical area0.50.91.71.3-1.11.1-1.21.21.11.11.11.2-1.3-1.21.21.0-0.9-0.80.71.00.80.80.40.70.50.4-0.4-0.3-0.7
Bone: cortical porosity1.21.33.10.5-1.51.5-0.11.00.50.11.41.2-0.1-1.31.2-0.5-0.1-1.8-0.70.11.51.5-1.01.61.6-1.21.21.1-1.3
Bone: cortical porosity1.51.63.41.0-1.81.8-0.51.40.80.51.71.5-0.5-1.61.6-0.1-0.4-1.8-0.40.41.71.7-0.81.71.7-1.01.00.8-1.5
Bone: cortical thickness0.10.20.40.6-0.60.6-0.50.60.50.50.50.5-0.6-0.60.60.4-0.5-0.50.30.10.40.40.00.40.40.1-0.1-0.1-0.5
Bone: cortical thickness0.60.71.3-1.01.2-1.10.9-1.1-0.9-0.8-1.1-1.10.71.1-1.0-0.50.51.0-0.4-0.2-1.0-1.0-0.2-0.8-0.60.1-0.10.00.6
Bone: cortical tissue density1.01.53.1-1.41.7-1.81.1-1.7-1.3-1.0-1.7-1.70.91.5-1.5-0.50.61.6-0.4-0.7-1.6-1.6-0.1-1.4-1.20.4-0.4-0.30.9
Condit. Reinf. active minus inactive responses0.70.81.70.8-1.21.2-0.51.10.60.51.31.1-0.3-1.11.10.1-0.1-1.1-0.11.01.21.2-0.31.21.1-0.60.60.5-0.9
Condit. Reinf. active-inactive response ratio0.80.92.1-0.9-0.10.11.2-0.4-1.0-1.20.1-0.21.30.0-0.0-1.41.4-0.1-1.4-0.10.50.5-1.30.80.9-1.51.51.4-0.6
Condit. Reinf. active responses1.62.03.61.8-1.81.8-1.61.91.71.61.81.8-1.4-1.71.61.1-1.2-1.70.91.51.51.50.61.10.90.2-0.2-0.3-0.8
Condit. Reinf. inactive responses3.95.09.83.1-2.12.1-3.12.63.13.11.92.3-3.1-1.91.82.9-3.1-2.02.71.51.21.12.20.5-0.11.8-2.0-1.9-0.1
Incentive salience index mean1.72.24.51.4-2.12.1-0.91.81.20.92.11.9-0.8-2.01.90.3-0.6-2.0-0.01.52.02.0-0.31.81.7-0.80.80.6-1.4
Condit. Reinf. lever presses2.23.26.42.0-2.52.5-1.52.31.81.42.52.3-1.4-2.42.40.8-1.1-2.30.51.82.22.20.11.91.7-0.50.40.3-1.6
Condit. Reinf. active minus inactive responses0.20.30.80.6-0.20.2-0.70.50.70.60.30.4-0.6-0.30.40.7-0.9-0.40.7-0.50.10.10.7-0.1-0.30.6-0.6-0.60.3
Condit. Reinf. active-inactive response ratio0.10.21.5-0.60.4-0.40.6-0.5-0.6-0.6-0.4-0.50.60.4-0.3-0.50.10.0-0.5-1.2-0.3-0.3-0.4-0.1-0.0-0.30.30.40.1
Condit. Reinf. active responses0.50.71.61.0-0.20.2-1.20.71.01.10.30.5-1.1-0.20.31.2-1.2-0.21.30.0-0.0-0.11.2-0.4-0.61.1-1.1-1.00.6
Condit. Reinf. inactive responses1.01.53.61.4-0.20.2-1.71.01.51.60.40.7-1.7-0.20.21.9-1.4-0.11.91.1-0.0-0.11.9-0.6-1.01.6-1.7-1.40.8
Condit. Reinf. lever presses1.11.63.01.7-1.51.5-1.61.71.61.41.61.6-1.5-1.41.41.2-1.2-1.30.91.71.21.20.51.00.70.3-0.3-0.2-0.9
Condit. Reinf. lever reinforcers received0.40.61.51.0-0.30.3-1.20.71.01.10.40.6-1.1-0.30.41.2-1.2-0.31.2-0.10.0-0.01.0-0.2-0.41.0-1.1-0.90.4
Conditioned reinforcement - actives0.20.71.5-0.21.0-1.0-0.2-0.6-0.20.0-1.0-0.7-0.40.9-1.10.6-0.31.00.7-0.6-1.1-1.10.9-1.2-1.21.0-1.0-0.71.2
Conditioned reinforcement - inactives0.61.84.81.6-0.40.4-1.91.01.41.80.50.7-1.90.3-0.02.2-1.90.12.1-0.4-0.2-0.31.7-0.6-0.91.8-1.9-1.81.1
Conditioned locomotion0.50.73.8-0.61.0-1.00.5-0.9-0.9-0.4-0.9-0.90.31.1-1.2-0.10.51.5-0.1-1.9-1.0-1.0-0.2-0.7-0.60.3-0.3-0.20.8
Patch foraging indifference point 0 sec3.18.716.74.1-3.13.1-3.93.84.03.83.03.5-3.9-3.13.03.4-3.5-2.83.02.82.32.22.31.30.71.7-1.8-1.5-1.1
Patch foraging indifference point AUC1.22.87.2-2.21.7-1.72.2-2.0-2.4-2.2-1.5-1.81.91.7-1.6-1.82.01.5-1.7-2.7-1.2-1.2-1.6-0.6-0.2-1.00.91.00.8
Delay disc. indifference point, 0s delay1.51.73.11.7-1.51.5-1.61.71.81.71.51.6-1.5-1.41.61.3-1.4-1.41.20.61.21.21.00.70.40.5-0.6-0.6-0.4
Delay disc. indifference point, 16s delay0.10.10.6-0.10.4-0.4-0.1-0.2-0.20.0-0.3-0.3-0.00.3-0.40.20.10.80.1-0.6-0.4-0.40.1-0.3-0.30.3-0.1-0.30.2
Delay disc. indifference point, 2s delay1.82.03.91.2-2.02.0-0.81.71.10.72.01.8-0.7-1.91.90.1-0.4-1.7-0.10.92.02.0-0.31.71.6-0.91.00.8-1.5
Delay disc. indifference point, 24s delay0.10.20.4-0.50.3-0.20.6-0.4-0.6-0.6-0.2-0.30.50.3-0.4-0.60.60.3-0.6-0.5-0.0-0.1-0.60.10.2-0.50.60.6-0.3
Delay disc. indifference point, 4s delay0.60.61.4-0.3-0.50.50.50.1-0.3-0.70.60.30.6-0.50.5-0.90.8-0.4-1.00.20.70.7-1.21.01.1-1.21.21.2-1.2
Delay disc. indifference point, 8s delay0.10.10.40.30.1-0.0-0.50.20.20.50.10.1-0.5-0.10.20.5-0.10.60.40.6-0.1-0.10.2-0.1-0.10.4-0.2-0.4-0.1
Indifference point function ln k0.51.65.61.6-1.31.3-1.61.51.71.61.21.4-1.5-1.51.41.3-1.3-1.01.22.41.01.01.00.50.20.7-0.6-0.7-0.8
Indifference point function log k0.51.65.61.6-1.31.3-1.61.51.71.61.21.4-1.5-1.51.41.3-1.3-1.01.22.41.01.01.00.50.20.7-0.6-0.7-0.8
Patch foraging total patch changes 0 sec2.98.515.94.0-3.23.2-3.73.73.83.73.13.5-3.7-3.23.13.2-3.3-2.92.73.02.42.32.01.60.91.4-1.5-1.3-1.3
Patch foraging total patch changes 12 sec0.91.22.41.5-1.31.3-1.31.51.31.31.41.5-1.5-1.21.31.1-1.0-1.20.90.81.11.00.60.80.60.3-0.4-0.2-0.5
Patch foraging total patch changes 18 sec0.30.61.71.0-0.40.4-1.10.80.91.20.60.6-1.3-0.20.31.3-0.8-0.21.11.10.10.00.8-0.1-0.20.9-1.1-0.90.4
Patch foraging total patch changes 24 sec0.82.74.72.0-2.22.1-1.72.11.81.72.22.1-1.6-2.02.11.2-1.4-2.00.82.01.81.70.41.51.20.0-0.2-0.1-1.2
Patch foraging total patch changes 6 sec0.40.61.41.1-1.00.9-1.01.01.01.00.90.9-1.2-0.60.60.9-1.0-1.00.80.10.60.60.50.40.20.3-0.3-0.3-0.1
Patch foraging time to switch 0 sec0.10.33.20.30.0-0.0-0.50.30.60.50.00.2-0.30.2-0.00.4-0.5-0.10.61.80.10.10.9-0.4-0.50.4-0.4-0.20.3
Patch foraging water rate 0 sec0.10.51.20.5-1.01.0-0.20.70.30.20.80.8-0.2-1.00.8-0.1-0.0-1.0-0.4-0.80.90.9-0.71.11.1-0.70.60.3-0.8
Patch foraging water rate 12 sec0.20.71.80.7-1.21.1-0.50.90.50.51.21.0-0.3-1.31.20.1-0.0-0.9-0.10.91.11.1-0.31.11.0-0.50.40.3-0.9
Patch foraging water rate 18 sec0.51.03.4-0.6-0.60.60.8-0.2-0.8-1.10.30.11.0-0.60.4-1.20.8-0.7-1.5-0.90.60.6-1.81.21.5-1.51.41.4-1.3
Patch foraging water rate 24 sec0.30.40.8-0.70.8-0.90.5-0.9-0.7-0.6-0.9-0.90.40.7-0.9-0.20.30.7-0.3-0.3-0.9-0.9-0.3-0.6-0.40.2-0.3-0.10.3
Patch foraging water rate 6 sec1.21.74.10.7-1.81.8-0.01.20.20.11.61.4-0.1-1.71.6-0.50.4-1.5-0.9-0.01.71.7-1.32.02.0-1.41.21.1-1.5
Seeking ratio, delayed vs. immediate footshock1.21.83.71.9-1.31.3-1.91.71.81.81.21.6-1.8-1.61.41.6-1.5-0.81.40.61.00.91.10.50.20.9-0.7-1.1-0.2
Distance traveled before self-admin0.81.83.80.5-1.71.70.21.10.2-0.21.71.30.1-1.51.4-0.70.3-1.5-0.90.61.81.8-1.31.91.9-1.61.51.4-1.7
Distance traveled after self-admin0.81.43.1-0.3-1.01.00.90.3-0.8-1.00.90.61.0-0.81.0-1.41.1-0.8-1.5-0.71.21.2-1.71.51.7-1.81.71.5-1.2
Extensor digitorum longus weight5.421.553.1-3.3-1.71.75.2-0.9-4.0-5.11.60.25.1-1.61.4-6.65.6-1.8-6.9-1.23.23.3-7.24.95.8-7.37.37.2-5.1
Bone: elastic displacement1.21.53.01.6-1.51.5-1.31.71.51.61.61.7-1.3-1.71.70.9-0.7-1.00.81.11.41.40.51.10.80.1-0.1-0.4-0.9
Bone: elastic work3.24.27.42.6-2.72.6-2.22.72.42.22.62.7-2.3-2.72.71.6-1.7-2.31.21.52.22.20.71.81.40.2-0.3-0.4-1.4
Bone: endosteal estimation0.20.62.21.0-0.70.7-0.90.90.90.80.70.9-0.9-0.90.90.8-0.7-0.40.71.50.60.60.60.30.10.4-0.4-0.4-0.3
Bone: endosteal perimeter0.71.73.11.7-1.61.5-1.51.71.61.41.51.6-1.4-1.61.71.1-1.2-1.21.01.71.31.30.80.90.60.3-0.3-0.3-0.7
Epididymis fat weight0.20.82.20.70.2-0.3-1.00.20.81.2-0.3-0.0-1.10.1-0.11.3-1.10.41.30.4-0.6-0.61.3-0.9-1.11.4-1.3-1.50.8
Delta time in closed arm before/after self-admin1.00.92.60.90.2-0.2-1.20.40.81.2-0.10.1-1.30.2-0.41.5-1.20.61.5-0.6-0.5-0.61.3-0.8-1.01.4-1.6-1.51.0
Delta time in open arm before/after self-admin0.10.10.4-0.2-0.00.00.2-0.1-0.3-0.50.0-0.00.4-0.10.0-0.40.4-0.0-0.4-0.00.10.2-0.40.20.3-0.40.60.6-0.3
Diff in mean of infusions in LGA sessions0.40.82.40.5-1.21.20.00.80.50.11.11.0-0.2-1.01.2-0.3-0.2-1.5-0.40.41.21.2-0.51.21.1-0.80.91.0-1.0
Delay discount exponential model param0.20.30.8-0.30.6-0.60.1-0.5-0.1-0.0-0.7-0.60.10.7-0.60.1-0.30.20.3-0.1-0.7-0.70.6-0.8-0.90.6-0.6-0.60.9
Extinction: sum of active levers before priming0.50.82.11.0-0.10.2-1.20.51.21.30.00.3-1.3-0.20.21.4-1.4-0.41.30.4-0.3-0.31.2-0.6-0.71.3-1.2-1.20.6
Active lever presses in extinction session 61.01.02.4-0.81.3-1.30.4-1.2-0.7-0.5-1.6-1.30.31.4-1.50.00.10.80.2-0.7-1.4-1.40.3-1.3-1.20.7-0.7-0.61.3
Bone: final force0.20.40.90.8-0.70.7-0.70.80.60.60.80.8-0.6-0.90.90.4-0.3-0.40.30.90.70.70.20.50.40.1-0.0-0.1-0.6
Bone: final moment0.71.12.11.3-1.21.2-1.21.31.11.11.21.3-1.1-1.41.40.8-0.7-0.80.71.41.01.00.40.80.60.2-0.2-0.3-0.9
Food consumed during 24 hour testing period0.61.23.11.5-0.90.9-1.71.11.31.80.81.0-1.6-1.11.11.6-1.3-0.51.20.50.30.30.60.30.21.0-1.0-1.3-0.4
Glucose0.81.23.3-1.31.5-1.61.0-1.5-1.3-0.8-1.6-1.50.91.2-1.1-0.51.01.8-0.50.1-1.4-1.4-0.4-1.0-0.80.3-0.2-0.00.4
Heart weight0.60.92.30.70.4-0.4-1.10.20.81.2-0.3-0.0-1.20.2-0.31.4-1.00.51.4-0.4-0.7-0.71.3-1.0-1.11.5-1.4-1.51.0
Delay discount hyperbolic model param0.30.41.0-0.40.8-0.80.2-0.6-0.2-0.1-0.9-0.70.10.8-0.80.1-0.20.40.4-0.2-0.9-0.90.6-1.0-1.00.7-0.7-0.61.0
Intermittent access intake day 1-15 change0.10.81.90.10.7-0.7-0.4-0.40.40.6-0.8-0.5-0.60.8-0.40.9-0.80.31.0-1.2-1.0-1.11.0-1.2-1.21.3-1.3-1.41.2
Intermittent access intake escalation0.10.82.10.20.5-0.6-0.5-0.30.50.7-0.7-0.4-0.80.7-0.40.9-0.90.11.0-1.4-0.9-0.91.0-1.0-1.11.3-1.2-1.41.2
Intermittent access intake escalation 20.30.51.7-0.10.7-0.7-0.2-0.50.10.3-0.8-0.6-0.40.7-0.40.6-0.50.50.6-1.3-1.0-1.00.6-0.9-0.91.0-1.0-1.10.9
Intermitt. access day 1 inactive lever presses0.00.52.4-0.61.2-1.10.4-0.7-0.5-0.3-0.9-0.80.40.9-0.9-0.20.61.60.1-0.4-0.7-0.70.4-0.9-0.90.3-0.1-0.30.7
Intermitt. access day 15 inactive lever presses0.10.72.7-0.71.1-1.10.5-0.9-1.0-0.5-1.0-0.90.51.2-0.9-0.10.41.3-0.2-1.6-1.0-1.0-0.4-0.7-0.50.3-0.3-0.20.7
Intermitt. access escalation Index0.00.10.40.3-0.30.3-0.40.30.50.40.20.3-0.1-0.60.40.2-0.3-0.30.30.60.30.30.40.0-0.10.2-0.1-0.5-0.0
Intermittent access day 1 total infusions0.00.00.50.2-0.10.2-0.20.2-0.20.00.20.2-0.2-0.1-0.10.20.00.30.10.70.10.1-0.20.20.3-0.0-0.10.2-0.0
Intermittent access day 15 total infusions0.30.71.90.00.7-0.8-0.3-0.40.00.4-0.8-0.6-0.60.9-0.90.8-0.60.70.8-0.9-1.0-1.10.7-1.0-1.11.1-1.2-1.21.4
Intermittent access terminal intake (last 3 days)0.40.71.9-0.51.0-1.00.3-0.9-0.6-0.2-1.1-1.00.01.4-1.10.3-0.00.90.2-1.1-1.2-1.30.1-1.0-0.90.6-0.8-0.71.3
Intermittent access total infusions0.70.82.1-0.20.9-1.0-0.1-0.6-0.20.2-1.0-0.8-0.31.2-1.40.6-0.31.10.7-0.8-1.2-1.20.6-1.1-1.10.9-1.1-1.01.4
Intermittent access day 1 locomotion0.30.61.31.2-0.80.8-1.01.10.71.00.91.0-1.1-0.80.50.9-0.60.00.80.90.70.70.40.50.30.3-0.5-0.2-0.2
Intermittent access day 15 total locomotion0.10.52.4-0.41.0-1.00.2-0.7-0.7-0.1-0.8-0.80.00.9-1.00.20.41.60.1-1.0-1.0-1.0-0.1-0.7-0.60.5-0.5-0.40.6
Intermittent access total locomotion0.10.10.50.40.0-0.0-0.30.20.10.50.10.2-0.50.1-0.40.5-0.10.70.4-0.5-0.1-0.10.2-0.0-0.10.3-0.4-0.30.3
Intermittent access standard deviation0.00.32.1-0.40.5-0.50.4-0.6-0.7-0.2-0.6-0.60.20.4-0.2-0.10.20.4-0.4-1.4-0.7-0.7-0.7-0.20.10.1-0.1-0.20.2
Left kidney weight0.21.32.71.5-1.51.4-1.51.41.31.71.21.4-1.4-1.51.31.2-1.2-1.20.8-0.20.90.90.20.90.80.4-0.4-0.7-0.7
Right kidney weight0.64.07.32.7-2.52.5-2.52.62.42.62.32.5-2.5-2.52.31.9-2.0-2.21.51.11.81.80.81.51.20.5-0.5-0.8-1.2
Cocaine induced anxiety1.02.75.32.0-2.12.1-1.52.21.51.52.32.3-1.5-2.02.00.9-0.8-0.90.62.12.12.10.21.81.5-0.40.30.3-1.5
Post-drug Anxiety2.93.36.72.6-1.81.8-2.52.42.42.62.02.2-2.4-1.81.92.0-1.7-0.61.91.81.51.51.60.80.41.0-1.0-1.3-0.7
Baseline Anxiety0.50.92.50.00.9-0.9-0.5-0.40.40.7-0.9-0.6-0.30.7-0.70.8-0.60.51.0-1.0-1.1-1.01.2-1.3-1.41.3-1.3-1.61.2
Tail length0.42.15.72.0-0.90.9-2.31.51.92.41.01.3-2.2-0.90.82.2-1.7-0.52.01.00.40.41.6-0.1-0.41.6-1.5-1.80.1
Length with tail0.73.05.42.2-2.12.1-1.92.22.12.12.12.2-2.0-2.22.21.3-1.2-1.51.12.31.81.80.81.31.00.2-0.1-0.6-1.2
Length without tail0.73.78.40.8-2.22.20.01.60.50.12.31.90.1-2.52.7-0.90.8-1.7-1.22.92.52.6-1.42.62.5-1.92.11.7-2.7
Times rat made contact with spout0.50.61.80.10.6-0.7-0.6-0.40.20.6-0.7-0.5-0.50.5-0.50.9-0.60.70.8-0.9-1.0-1.00.7-1.0-1.01.2-1.2-1.30.9
Lifetime Intake0.40.51.4-0.20.7-0.7-0.1-0.5-0.30.1-0.8-0.6-0.31.0-1.20.5-0.21.00.5-0.9-0.9-1.00.3-0.8-0.80.7-0.8-0.71.2
Liver weight, left1.32.25.70.9-2.01.9-0.41.30.70.31.61.6-0.2-2.42.2-0.3-0.0-1.5-0.72.11.81.8-1.01.91.9-1.11.21.2-2.3
Liver weight, right0.81.44.3-1.50.8-0.81.6-1.3-1.7-1.5-0.8-1.01.70.1-0.2-1.62.11.5-1.70.1-0.4-0.3-1.60.20.5-1.11.31.2-1.0
Locomotor activity4.97.615.82.7-4.03.9-1.93.42.42.03.83.6-1.5-3.63.70.6-1.2-3.80.21.63.73.7-0.53.43.0-1.41.40.9-2.7
Locomotor testing distance3.48.414.93.7-3.73.7-3.23.93.73.33.53.8-2.9-3.53.52.2-2.8-3.62.02.33.13.11.52.21.60.4-0.4-0.7-1.5
Locomotor testing rearing3.111.420.34.4-4.24.1-3.84.54.33.84.14.4-3.6-4.14.22.8-3.3-3.82.53.03.53.51.92.41.70.7-0.8-0.8-1.8
Locomotion in novel chamber0.20.30.80.5-0.0-0.0-0.90.20.70.9-0.00.1-0.40.1-0.20.9-0.7-0.20.8-0.0-0.4-0.30.7-0.4-0.50.8-0.7-0.80.5
Locomotion in novel chamber post-restriction0.20.75.4-0.50.1-0.10.6-0.2-1.1-0.80.3-0.00.8-0.10.2-0.91.20.6-1.0-2.30.30.3-1.30.70.9-1.01.00.8-0.4
Fecal boli incidents, locomotor time 10.10.20.70.1-0.50.50.00.3-0.1-0.00.50.3-0.1-0.50.5-0.10.2-0.1-0.30.80.40.4-0.50.60.6-0.40.20.4-0.8
Change in fecal boli incidents, locomotor task1.01.13.3-1.41.1-1.11.3-1.1-1.3-1.0-1.0-1.01.50.7-0.8-1.41.81.6-1.10.2-0.4-0.3-0.6-0.3-0.1-0.81.10.7-0.1
Time >=10cm from walls, locomotor time 10.91.12.71.3-0.50.5-1.60.91.61.60.40.7-1.2-0.70.71.5-1.6-1.01.50.6-0.00.11.4-0.4-0.61.3-1.1-1.40.1
Bouts of movement, locomotor time 11.51.99.9-1.50.0-0.12.0-1.0-1.3-1.6-0.5-0.71.70.3-0.3-2.11.5-0.7-2.0-3.20.20.3-1.80.71.0-1.91.71.5-0.2
Total resting periods, locomotor time 12.52.811.1-2.20.9-0.92.5-1.6-2.0-2.1-1.1-1.32.21.0-1.0-2.52.10.3-2.3-3.3-0.4-0.3-2.00.20.6-1.81.81.60.0
Rest time, locomotor task time 11.72.85.6-2.31.7-1.72.4-2.1-2.3-2.3-1.6-1.82.01.4-1.4-2.12.21.6-1.9-1.7-1.1-1.1-1.5-0.5-0.2-1.11.21.20.3
Distance moved, locomotor task time 10.51.54.51.5-0.80.7-1.81.21.61.60.50.9-1.7-0.60.61.7-1.8-1.01.72.10.30.31.5-0.2-0.51.3-1.1-1.20.2
Vertical activity count, locomotor time 10.53.36.22.1-2.52.5-1.72.31.81.42.22.3-1.4-2.32.31.0-1.4-2.40.72.42.12.10.21.81.5-0.30.20.4-1.7
Time >=10cm from walls, locomotor time 20.10.21.3-0.30.2-0.20.4-0.2-0.4-0.5-0.0-0.10.5-0.30.3-0.60.70.4-0.61.10.20.2-0.40.30.3-0.50.70.6-1.0
Bouts of movement, locomotor time 20.82.66.5-2.20.7-0.72.5-1.6-2.0-2.3-1.0-1.32.30.9-0.9-2.52.20.2-2.4-0.9-0.2-0.2-2.00.30.7-1.92.01.7-0.4
Total resting periods, locomotor time 20.93.68.6-2.61.1-1.12.9-2.1-2.4-2.6-1.4-1.72.71.3-1.3-2.82.50.6-2.7-1.6-0.6-0.6-2.30.10.6-2.02.11.8-0.3
Rest time, locomotor task time 22.33.87.6-2.62.0-1.92.5-2.5-2.7-2.3-2.0-2.32.22.0-1.9-2.12.21.7-2.1-2.8-1.7-1.6-2.1-0.7-0.1-1.11.21.10.3
Distance moved, locomotor task time 22.73.615.42.4-1.41.4-2.62.02.52.21.41.8-2.4-1.61.62.3-2.4-1.32.23.90.90.92.00.2-0.31.6-1.4-1.4-0.4
Vertical activity count, locomotor time 21.63.812.42.3-2.42.4-1.82.52.01.52.42.5-1.6-2.52.51.2-1.5-1.90.93.52.22.20.61.71.3-0.1-0.10.1-1.8
Light reinforcement 10.52.36.10.51.2-1.2-1.2-0.40.81.4-1.4-0.7-1.10.7-0.51.8-1.71.21.80.6-1.7-1.71.9-1.9-2.02.5-2.3-2.31.6
Light reinforcement 21.53.47.5-1.72.6-2.51.0-2.2-1.5-0.8-2.7-2.30.82.3-2.3-0.20.72.70.0-1.8-2.5-2.50.3-2.2-2.01.1-1.0-1.22.0
Bone: marrow area0.30.62.21.1-0.70.7-1.00.91.00.90.70.9-1.0-0.90.90.9-0.8-0.40.91.50.50.50.80.20.00.6-0.6-0.5-0.3
Bone: maximum diameter0.10.20.60.3-0.60.6-0.10.40.00.10.60.5-0.2-0.70.8-0.1-0.0-0.5-0.30.20.50.5-0.50.70.7-0.40.40.4-0.7
Bone: maximum force0.61.12.71.1-1.41.3-0.81.30.80.71.41.4-0.8-1.61.60.4-0.3-0.90.11.51.31.3-0.11.21.1-0.30.40.3-1.3
Bone: maximum moment1.22.24.71.7-1.91.9-1.41.91.41.31.91.9-1.4-2.12.20.9-0.8-1.30.62.01.71.70.21.51.2-0.10.10.1-1.5
Mean time between licks in bursts0.21.53.91.10.2-0.1-1.50.61.31.60.10.3-1.50.1-0.11.7-1.30.51.81.8-0.3-0.32.0-1.0-1.31.6-1.6-1.91.3
Mean num. licks in bursts0.20.41.10.9-0.50.4-0.90.60.80.90.30.5-1.0-0.60.61.0-1.0-0.50.80.20.0-0.00.50.0-0.10.8-0.9-0.5-0.1
Cd content in liver1.71.93.90.8-1.71.7-0.21.30.40.11.81.5-0.2-1.61.6-0.40.2-1.3-0.71.21.91.9-1.02.01.9-1.41.31.5-2.0
Co content in liver2.42.87.3-1.90.6-0.62.3-1.2-2.3-2.4-0.4-0.92.30.4-0.4-2.52.71.1-2.4-0.60.20.2-2.30.81.2-2.12.22.2-1.1
Cu content in liver0.50.61.9-0.90.6-0.61.0-0.7-1.1-0.9-0.3-0.51.00.4-0.4-1.01.41.1-1.1-0.4-0.1-0.1-1.10.30.5-0.90.80.9-0.6
Fe content in liver0.91.12.90.90.2-0.2-1.30.41.11.3-0.20.1-1.30.2-0.21.5-1.40.11.60.7-0.5-0.61.7-1.0-1.21.6-1.7-1.51.0
K content in liver1.01.02.5-0.51.3-1.3-0.1-0.8-0.20.2-1.2-1.00.11.3-1.30.4-0.11.00.6-0.3-1.3-1.30.8-1.4-1.41.0-0.9-1.01.6
Mg content in liver0.80.92.20.30.8-0.8-0.8-0.20.40.8-0.7-0.4-0.80.7-0.71.2-0.71.01.2-0.4-1.0-1.01.2-1.2-1.31.5-1.4-1.41.3
Mn content in liver1.11.33.11.2-0.00.1-1.70.71.31.60.10.5-1.50.0-0.01.8-1.5-0.11.70.1-0.3-0.31.6-0.7-1.01.6-1.6-1.61.0
Na content in liver2.42.75.41.3-2.32.3-0.61.80.90.62.12.0-0.5-2.32.3-0.1-0.4-2.2-0.50.12.12.2-1.12.32.2-1.31.21.1-2.1
Rb content in liver0.10.10.4-0.20.5-0.40.0-0.3-0.00.1-0.4-0.4-0.00.6-0.60.2-0.10.20.20.2-0.5-0.50.3-0.5-0.50.3-0.3-0.40.6
Se content in liver3.03.56.92.6-2.02.0-2.52.62.42.42.32.5-2.3-2.02.01.9-1.7-1.31.72.01.91.81.31.20.80.6-0.7-0.6-0.8
Sr content in liver0.10.10.30.3-0.10.2-0.20.40.10.20.30.4-0.2-0.30.30.10.20.50.1-0.20.30.40.10.20.2-0.10.00.1-0.2
Zn content in liver0.40.41.01.0-0.50.6-1.00.90.80.90.80.9-0.9-0.60.60.8-0.40.10.71.00.60.60.60.30.10.3-0.4-0.2-0.3
Bone: minimum diameter1.01.93.71.7-1.81.8-1.41.81.41.31.81.8-1.4-1.91.91.0-0.8-1.20.71.51.51.50.21.31.10.0-0.1-0.1-1.3
Time in familiar zone, hab. session 10.20.21.9-0.20.6-0.60.1-0.4-0.2-0.1-0.5-0.40.10.4-0.40.00.20.70.2-1.4-0.5-0.50.3-0.5-0.50.3-0.3-0.20.4
Time in novel zone, hab. session 10.91.02.4-1.20.2-0.21.4-0.8-1.2-1.4-0.3-0.61.40.3-0.3-1.41.30.1-1.50.30.00.1-1.50.50.8-1.31.31.3-0.7
Total zone transitions, hab. session 10.50.71.81.0-1.21.1-0.61.10.70.61.11.1-0.7-1.31.30.3-0.3-0.80.20.11.01.0-0.11.00.9-0.20.20.2-0.9
Total locomotion distance, hab. session 11.01.42.51.6-1.61.5-1.31.61.51.21.51.6-1.3-1.51.51.0-1.3-1.50.90.21.21.20.60.90.60.2-0.3-0.2-0.7
Locomotion velocity, hab. session 12.23.15.52.3-2.22.2-2.02.32.31.92.12.2-2.1-2.12.11.6-2.1-2.21.40.81.71.71.01.20.80.5-0.6-0.5-0.8
Time in familiar zone, hab. session 22.02.24.4-2.11.7-1.72.0-1.9-1.9-1.9-1.7-1.82.01.6-1.4-1.81.81.6-1.4-1.3-1.1-1.0-0.7-0.9-0.6-0.80.90.50.8
Time in novel zone, hab. session 21.11.22.11.5-1.41.4-1.31.41.31.21.31.3-1.3-1.21.11.1-1.3-1.40.81.21.00.90.40.80.60.3-0.5-0.2-0.7
Total zone transitions, hab. session 21.72.14.30.9-1.91.9-0.11.50.5-0.11.91.7-0.2-1.81.8-0.50.2-1.8-0.71.02.12.0-1.02.12.0-1.51.31.5-1.9
Total locomotion distance, hab. session 20.70.92.00.8-1.41.4-0.31.10.60.11.31.2-0.4-1.21.2-0.0-0.3-1.4-0.10.61.41.3-0.31.31.1-0.70.60.8-1.0
Locomotion velocity, hab. session 21.11.53.00.9-1.71.7-0.31.40.70.11.71.5-0.4-1.51.6-0.2-0.2-1.7-0.30.61.71.7-0.61.61.5-1.00.91.1-1.4
Novel to familiar place preference ratio0.60.83.91.1-0.80.8-1.11.01.21.00.80.9-0.9-0.90.90.9-0.8-0.60.82.00.70.60.70.30.10.5-0.5-0.5-0.5
Novelty place preference0.60.83.71.1-0.90.9-1.11.11.21.00.91.0-0.9-0.91.00.9-0.9-0.80.81.90.80.70.80.40.20.4-0.4-0.4-0.5
Time in novel zone, NPP test0.60.83.21.0-1.11.1-0.91.11.10.81.01.1-0.7-1.01.10.6-0.7-1.00.51.81.00.90.50.60.40.1-0.1-0.2-0.7
Total zone transitions, NPP test0.81.22.31.5-1.31.2-1.31.51.41.41.31.4-1.4-1.41.41.1-1.2-1.11.00.61.01.00.80.70.40.4-0.5-0.3-0.5
Total locomotion distance, NPP test2.33.36.92.4-1.21.2-2.62.02.52.51.21.7-2.6-1.11.12.5-2.5-1.22.50.70.70.62.4-0.2-0.71.9-1.9-1.80.5
Locomotion velocity, NPP test2.02.96.32.3-1.01.0-2.51.72.32.41.01.4-2.5-0.91.02.5-2.4-0.92.50.90.50.42.3-0.3-0.81.9-2.0-1.70.5
Intraocular pressure0.30.41.20.8-0.20.2-0.80.60.90.90.30.5-0.8-0.30.50.9-0.70.01.00.60.20.11.1-0.3-0.50.8-0.8-0.80.4
Delta distance traveled before/after self-admin1.01.12.7-1.30.7-0.71.4-1.0-1.6-1.6-0.6-0.81.70.5-0.2-1.61.60.6-1.4-0.7-0.2-0.2-1.10.10.3-1.11.11.2-0.3
Delta ambulatory time before/after self-admin0.61.02.5-1.20.4-0.31.4-0.8-1.4-1.6-0.4-0.61.50.20.0-1.51.50.3-1.4-0.40.10.1-1.20.40.6-1.21.21.4-0.5
Parametrial fat weight1.12.67.31.20.6-0.6-1.80.41.51.9-0.60.0-2.00.1-0.32.2-1.90.72.41.3-0.9-0.92.7-1.7-2.02.5-2.2-2.31.6
Pavlov. Cond. lever latency0.91.12.2-1.31.4-1.41.1-1.3-1.2-1.1-1.3-1.31.21.3-1.2-0.81.11.4-0.5-1.5-1.0-1.0-0.2-0.9-0.8-0.10.10.10.9
Pavlov. Cond. magazine entry latency0.20.30.80.7-0.20.2-0.80.40.60.80.20.3-0.9-0.30.30.9-0.7-0.00.70.2-0.1-0.10.5-0.1-0.20.7-0.7-0.70.0
Pavlov. Cond. change in total contacts2.22.34.61.2-2.12.1-0.71.60.80.62.01.8-0.7-2.12.00.0-0.0-1.6-0.41.61.92.0-0.92.02.0-1.11.01.0-2.1
Pavlov. Cond. index score0.60.81.51.1-1.21.2-0.91.10.80.91.11.1-1.0-1.21.10.7-0.7-1.10.40.80.90.8-0.00.90.80.0-0.0-0.1-0.8
Pavlov. Cond. latency score0.70.91.61.2-1.31.3-1.11.21.01.11.21.2-1.2-1.21.10.9-1.0-1.20.61.00.90.90.20.80.70.2-0.2-0.2-0.8
Pavlov. Cond. lever contacts0.80.91.51.2-1.21.2-1.11.21.11.21.11.1-1.2-1.11.00.9-1.1-1.20.71.20.80.80.30.70.60.3-0.3-0.4-0.6
Pavlov. Cond. magazine entry number0.20.30.6-0.60.8-0.80.4-0.6-0.3-0.4-0.7-0.60.60.8-0.7-0.30.20.6-0.0-0.2-0.5-0.50.4-0.7-0.70.1-0.1-0.10.7
Pavlov. Cond. intertrial magazine entries1.31.62.81.6-1.51.5-1.51.71.61.31.51.6-1.5-1.31.31.2-1.3-1.51.01.51.21.20.80.80.50.3-0.4-0.3-0.6
Pavlov. Cond. lever-magazine prob. diff.0.60.71.50.9-1.21.2-0.71.00.70.71.11.0-0.9-1.21.10.5-0.5-1.00.20.70.90.9-0.31.00.9-0.20.10.1-0.9
Pavlov. Cond. response bias0.20.20.50.5-0.70.7-0.40.50.30.40.60.5-0.5-0.60.60.3-0.2-0.50.00.40.50.4-0.30.60.6-0.10.10.1-0.7
Pavlov. Cond. lever latency1.62.34.4-1.22.0-2.00.8-1.7-1.0-0.6-2.1-1.80.61.8-1.8-0.10.11.80.3-1.8-2.0-2.00.8-2.0-1.91.1-1.1-1.12.0
Pavlov. Cond. magazine entry latency0.71.01.91.4-1.11.1-1.31.31.11.21.31.2-1.2-1.11.11.1-0.6-0.70.71.30.90.90.30.80.60.3-0.3-0.3-0.8
Pavlov. Cond. change in total contacts0.82.04.50.6-1.61.7-0.11.20.2-0.01.81.40.0-1.61.6-0.60.7-1.2-1.01.51.71.8-1.52.12.1-1.51.51.5-2.1
Pavlov. Cond. index score1.21.93.91.3-1.81.9-0.91.60.90.72.01.7-0.7-1.61.60.3-0.1-1.5-0.21.41.81.8-0.71.91.8-0.90.80.8-1.7
Pavlov. Cond. latency score1.32.04.21.5-1.91.9-1.11.81.11.02.01.8-1.0-1.71.70.5-0.3-1.60.11.61.81.8-0.51.81.7-0.70.60.6-1.6
Pavlov. Cond. lever contacts1.62.34.61.4-2.02.1-1.01.81.10.82.11.9-0.9-1.81.80.4-0.4-1.8-0.11.81.91.9-0.72.01.9-0.90.80.9-1.9
Pavlov. Cond. magazine entry number0.60.81.6-1.31.0-1.11.3-1.2-1.0-1.2-1.2-1.21.11.1-1.1-0.90.30.4-0.7-1.0-0.9-0.9-0.3-0.8-0.6-0.20.20.30.7
Pavlov. Cond. intertrial magazine entries1.63.510.01.40.4-0.5-2.10.61.92.0-0.50.1-2.10.4-0.42.5-2.70.22.9-0.2-1.0-1.13.2-1.9-2.42.9-2.9-2.72.1
Pavlov. Cond. lever-magazine prob. diff.1.11.73.41.1-1.71.7-0.71.50.70.51.81.6-0.5-1.51.50.10.0-1.4-0.31.21.71.7-0.81.81.8-1.00.90.9-1.7
Pavlov. Cond. response bias1.72.44.81.5-2.02.1-1.01.81.10.92.21.9-0.9-1.91.90.3-0.2-1.6-0.11.72.02.0-0.72.01.9-0.90.80.9-2.0
Time in closed arm before self-admin0.30.61.6-0.90.1-0.11.0-0.5-0.8-1.3-0.2-0.40.90.1-0.2-1.20.9-0.1-1.10.30.10.2-0.90.30.5-1.01.21.3-0.5
Time in closed arm after self-admin0.10.10.50.3-0.10.1-0.30.20.20.10.10.2-0.40.0-0.10.3-0.20.20.30.70.10.10.4-0.1-0.20.2-0.10.10.0
Time in open arm before self-admin0.20.31.00.5-0.70.6-0.30.60.70.40.50.6-0.4-0.30.60.3-0.7-1.00.40.70.50.50.50.20.10.1-0.2-0.2-0.1
Time in open arm after self-admin0.00.00.1-0.1-0.00.00.1-0.0-0.0-0.2-0.1-0.00.30.1-0.1-0.10.1-0.2-0.1-0.30.00.0-0.0-0.0-0.0-0.10.00.00.1
Bone: periosteal estimation0.41.02.21.3-1.11.0-1.21.21.11.11.01.2-1.3-1.21.21.0-0.9-0.70.91.50.80.70.60.50.30.5-0.5-0.4-0.5
Bone: periosteal perimeter0.51.12.11.4-1.31.2-1.21.31.21.11.21.3-1.2-1.41.40.9-0.9-0.80.81.31.01.00.60.70.50.4-0.4-0.4-0.6
Bone: post-yield work0.81.43.2-1.21.7-1.70.8-1.5-1.2-0.8-1.6-1.60.61.5-1.6-0.20.71.8-0.2-0.2-1.6-1.6-0.0-1.3-1.10.6-0.5-0.41.0
Progressive ratio test 1 active lever presses0.50.92.8-1.01.3-1.20.7-1.1-1.3-1.0-1.2-1.10.81.2-1.3-0.40.91.7-0.4-0.1-1.0-1.0-0.4-0.7-0.50.0-0.00.20.6
Progressive ratio test 1 breakpoint0.50.92.9-1.11.3-1.30.8-1.2-1.3-1.0-1.2-1.20.81.1-1.2-0.51.01.7-0.50.1-1.0-1.0-0.5-0.7-0.5-0.00.10.30.5
Progressive ratio test 1 inactive lever presses0.41.03.7-0.41.4-1.40.0-0.8-0.3-0.1-1.3-1.00.01.0-0.90.40.11.90.61.0-1.2-1.21.0-1.4-1.41.1-1.0-0.90.9
Progressive ratio test 2 active lever presses0.10.20.4-0.10.4-0.40.0-0.4-0.30.2-0.4-0.4-0.20.5-0.60.4-0.10.60.1-0.4-0.6-0.6-0.2-0.3-0.20.4-0.5-0.40.4
Progressive ratio test 2 breakpoint0.10.10.30.00.2-0.2-0.1-0.2-0.20.3-0.2-0.2-0.40.3-0.40.5-0.30.40.2-0.4-0.5-0.5-0.2-0.2-0.10.4-0.5-0.50.4
Progressive ratio test 2 inactive lever presses0.20.72.0-0.00.9-0.9-0.3-0.5-0.30.3-0.8-0.6-0.51.3-1.10.7-0.21.40.7-0.4-1.0-1.10.5-0.9-0.90.9-1.0-0.81.0
Incentive Sensitization - Responses0.30.91.91.3-1.21.1-1.11.11.11.41.11.1-1.4-1.11.01.2-1.2-0.90.80.10.60.60.10.70.60.5-0.6-0.6-0.5
Incentive Sensitization - Breakpoint0.51.02.41.4-1.21.2-1.21.21.21.51.11.1-1.5-1.11.01.3-1.4-1.00.9-0.10.60.50.20.60.50.6-0.8-0.8-0.4
Sum of active levers in priming session hrs 5-61.11.02.8-1.11.3-1.30.8-1.3-0.5-0.4-1.4-1.40.71.7-1.5-0.30.20.5-0.0-0.2-1.3-1.30.4-1.4-1.30.5-0.5-0.51.4
Progressive ratio0.20.61.4-0.1-0.70.80.40.3-0.2-0.40.40.40.5-0.90.6-0.70.4-1.0-0.9-1.00.70.7-1.21.11.2-1.01.01.0-0.9
Food seeking constrained by brief footshock4.65.811.1-3.32.3-2.33.3-3.0-3.1-3.1-2.4-2.73.22.5-2.4-2.92.71.4-2.5-3.3-1.7-1.6-2.0-0.9-0.4-1.51.41.70.9
Seeking ratio, punishment vs. effort0.71.63.6-1.71.5-1.61.4-1.7-1.5-1.5-1.4-1.71.51.9-1.7-1.11.11.1-0.8-1.3-1.3-1.3-0.5-1.1-0.8-0.20.10.31.1
Retroperitoneal fat weight0.21.02.80.40.7-0.8-1.0-0.10.71.1-0.6-0.3-0.70.4-0.51.1-0.80.91.40.7-0.8-0.81.7-1.3-1.41.5-1.2-1.51.2
Reaction time number correct0.20.91.9-1.31.1-1.11.3-1.2-1.1-1.2-1.0-1.01.30.6-0.8-1.21.41.2-1.00.0-0.6-0.5-0.5-0.5-0.3-0.50.70.60.1
Reaction time mean minus median0.10.62.20.5-1.01.0-0.10.80.40.11.00.8-0.0-0.80.8-0.1-0.1-1.0-0.21.51.01.0-0.30.90.8-0.60.50.5-0.8
Reaction time mean minus median AUC0.00.22.60.2-0.50.5-0.00.30.30.10.50.40.1-0.40.4-0.1-0.2-0.7-0.11.60.50.5-0.10.40.4-0.30.20.1-0.4
Reaction time num false alarms0.30.51.10.9-0.80.8-0.80.90.80.60.80.9-0.5-1.01.00.6-0.9-0.90.51.00.70.70.40.50.30.2-0.20.0-0.4
Reaction time num false alarms AUC0.20.41.00.8-0.80.7-0.80.80.60.50.80.8-0.5-0.91.00.5-0.9-0.90.40.90.60.60.30.50.40.2-0.10.1-0.6
Reaction time trials correct on left0.20.91.9-1.31.1-1.11.3-1.2-1.1-1.2-1.0-1.01.30.6-0.8-1.21.41.2-1.00.0-0.6-0.5-0.5-0.5-0.3-0.50.70.60.1
Reaction time trials on left0.20.81.6-1.31.1-1.11.2-1.1-1.1-1.2-1.1-1.01.20.7-0.8-1.11.21.2-0.80.1-0.6-0.6-0.4-0.5-0.4-0.40.60.50.2
Reaction time mean0.10.20.4-0.0-0.50.50.30.2-0.1-0.20.50.30.2-0.20.1-0.40.2-0.6-0.4-0.00.50.5-0.60.60.6-0.70.40.5-0.4
Reaction time mean AUC0.20.40.80.1-0.70.70.30.4-0.1-0.20.70.50.3-0.60.5-0.50.3-0.7-0.60.40.80.8-0.70.90.9-0.90.70.8-0.8
Median of all reaction times0.10.10.4-0.2-0.20.20.5-0.1-0.3-0.30.20.00.3-0.1-0.1-0.50.4-0.2-0.5-0.50.20.2-0.60.40.5-0.60.40.4-0.3
Reaction time omissions0.50.83.20.40.3-0.3-0.60.00.80.7-0.4-0.1-0.70.4-0.30.9-1.3-0.01.11.8-0.5-0.61.4-1.0-1.21.2-1.2-1.20.9
Reaction time false alarm rate0.40.61.71.1-0.80.8-1.11.00.90.90.80.9-0.9-0.70.91.0-1.3-1.00.80.40.50.40.50.30.20.5-0.5-0.3-0.3
Reaction time premature initiation rate0.50.82.4-0.90.1-0.11.1-0.6-1.1-0.9-0.1-0.41.30.2-0.2-1.41.2-0.0-1.4-1.60.20.3-1.40.60.8-1.31.31.1-0.3
Reaction time premature initiations0.51.63.9-1.70.7-0.81.8-1.2-1.7-1.5-0.8-1.02.00.6-0.6-2.01.80.7-1.8-1.5-0.2-0.1-1.60.30.6-1.51.61.3-0.2
Std. dev. reaction times0.10.20.90.1-0.60.50.10.30.1-0.10.60.30.2-0.10.1-0.20.0-0.7-0.31.00.50.5-0.40.50.5-0.60.40.4-0.3
Reaction time trials completed0.20.81.6-1.31.1-1.11.2-1.1-1.1-1.2-1.1-1.01.20.7-0.8-1.11.21.2-0.80.1-0.6-0.6-0.4-0.5-0.4-0.40.60.50.2
Reaction time trials AUC0.20.71.4-1.21.0-1.01.2-1.1-1.0-1.1-1.0-1.01.20.6-0.7-1.11.21.1-0.80.1-0.6-0.5-0.4-0.5-0.4-0.40.60.40.2
Run reversals in cocaine runway, females0.91.04.00.80.3-0.3-1.00.30.61.2-0.20.1-1.30.5-0.71.5-1.20.51.3-2.0-0.6-0.70.9-0.7-0.81.3-1.4-1.61.2
Run reversals in cocaine runway, males1.51.65.4-0.4-0.50.51.00.1-1.2-0.90.60.41.1-0.90.9-1.31.60.1-1.7-1.01.01.0-2.31.72.0-1.91.81.7-1.8
Latency to leave start box in cocaine runway0.81.13.7-0.90.4-0.41.1-0.5-1.5-1.3-0.2-0.31.30.00.2-1.41.91.4-1.4-0.10.30.3-1.50.70.9-1.31.21.5-1.0
Latency to leave start box in cocaine runway, F1.41.74.2-1.0-0.00.11.5-0.4-1.6-1.70.2-0.11.6-0.30.5-1.81.90.5-1.90.30.60.7-2.01.21.5-1.91.72.1-1.5
Latency to leave start box in cocaine runway, M0.10.11.6-0.10.4-0.3-0.0-0.1-0.3-0.1-0.2-0.10.10.0-0.0-0.10.71.3-0.1-0.2-0.00.0-0.0-0.0-0.0-0.00.20.0-0.1
Std. dev. time between licks in bursts2.34.38.52.8-1.91.9-2.72.52.92.71.82.2-2.8-1.81.82.5-2.6-1.52.42.81.41.32.30.4-0.21.5-1.6-1.60.1
Total sessions with >9 infusions0.10.21.3-0.40.5-0.50.3-0.4-0.6-0.3-0.4-0.40.20.4-0.6-0.20.61.1-0.2-0.3-0.3-0.3-0.2-0.2-0.1-0.10.10.10.4
Short access day 1 total inactive lever presses0.20.44.70.6-0.40.4-0.60.4-0.10.40.40.4-0.80.4-0.50.7-0.50.10.2-2.2-0.0-0.0-0.70.50.60.0-0.3-0.10.2
Short access day 10 total inactive lever presses0.00.11.5-0.10.6-0.6-0.0-0.2-0.20.1-0.4-0.2-0.10.4-0.10.10.21.20.20.0-0.4-0.40.3-0.4-0.40.4-0.3-0.30.0
Short access day 1 total infusions0.20.41.3-0.60.3-0.40.6-0.5-0.9-0.7-0.4-0.50.41.0-1.1-0.50.70.8-0.5-1.0-0.3-0.3-0.70.00.2-0.60.50.40.5
Short access day 10 total infusions0.30.51.40.5-1.01.0-0.20.80.10.11.00.9-0.3-1.00.8-0.10.1-0.4-0.30.41.01.0-0.81.21.2-0.70.60.6-0.8
Short access total infusions0.10.10.40.2-0.40.4-0.10.3-0.20.00.40.3-0.2-0.1-0.10.10.10.1-0.1-0.30.30.3-0.50.60.6-0.40.20.2-0.0
Short access day 1 locomotion0.40.71.60.5-1.01.1-0.00.80.10.01.10.9-0.3-1.01.0-0.20.1-0.5-0.41.01.11.1-0.81.21.2-0.80.80.9-1.2
Short access day 10 total locomotion0.10.40.91.0-0.70.8-0.91.00.70.90.90.9-0.9-0.40.20.7-0.4-0.10.6-0.70.60.60.20.60.40.1-0.2-0.0-0.1
Short access total locomotion0.40.61.30.9-0.91.0-0.71.10.40.61.11.1-0.8-1.00.80.4-0.10.10.20.41.01.0-0.21.00.9-0.30.20.4-0.9
One hour access (0.3 mA shock)0.30.41.10.60.0-0.0-0.70.20.61.0-0.00.1-0.7-0.2-0.41.0-0.70.30.9-0.0-0.3-0.40.6-0.4-0.40.8-1.0-1.00.5
Compulsive drug intake0.50.71.71.0-0.40.4-1.10.81.21.30.50.6-0.9-0.70.31.1-0.9-0.21.21.30.20.21.3-0.3-0.50.9-0.9-0.90.1
One hour access (shock baseline)0.00.11.1-0.20.2-0.20.3-0.3-0.3-0.1-0.3-0.3-0.00.4-0.7-0.10.10.1-0.1-1.1-0.3-0.3-0.4-0.10.0-0.1-0.00.00.5
Social response proportion2.02.55.8-1.82.2-2.21.3-2.0-1.6-1.1-2.2-2.11.52.0-1.9-0.91.52.4-0.6-1.1-1.9-1.7-0.1-1.6-1.40.2-0.1-0.61.4
Social responses2.02.66.70.41.5-1.5-1.1-0.50.61.2-1.4-0.8-1.00.9-0.81.6-1.01.82.00.1-1.7-1.62.4-2.2-2.42.5-2.3-2.62.0
Social time1.11.73.51.8-1.21.2-1.71.51.81.71.11.4-1.8-1.21.31.6-1.9-1.21.40.80.70.71.10.40.11.0-1.0-0.9-0.4
Soleus weight0.72.05.0-1.70.4-0.42.1-1.2-1.8-2.1-0.5-0.92.00.4-0.4-2.21.90.3-2.1-0.20.10.1-1.90.60.9-1.91.92.0-0.8
Bone: stiffness0.10.20.5-0.1-0.30.30.30.1-0.3-0.40.30.20.3-0.50.5-0.40.4-0.1-0.50.10.40.4-0.60.60.6-0.50.60.6-0.7
Tibialis anterior weight3.512.130.5-2.0-1.71.73.5-0.2-2.7-3.51.60.63.5-1.71.7-4.73.8-1.8-5.0-0.72.82.8-5.34.04.6-5.45.45.5-4.1
Time to tail flick, vehicle, before self-admin0.40.51.80.7-0.10.0-0.90.40.80.90.20.2-0.80.1-0.11.1-1.4-0.81.00.3-0.3-0.30.9-0.5-0.61.0-1.1-0.80.7
Time to tail flick, vehicle, after self-admin2.34.611.0-2.91.4-1.53.2-2.3-2.9-3.3-1.7-2.03.21.2-1.3-3.22.90.9-2.9-1.4-0.7-0.6-2.3-0.00.4-2.12.42.4-0.3
Time to tail flick, test, before self-admin1.92.26.11.50.1-0.1-2.10.81.62.20.10.5-2.0-0.0-0.12.3-1.80.42.2-0.6-0.5-0.52.1-1.0-1.32.1-2.2-2.51.3
Time to tail flick, test, after self-admin3.63.88.5-1.02.6-2.60.0-1.7-0.40.0-2.3-2.00.22.7-2.50.7-0.31.91.2-0.2-2.5-2.51.9-2.9-2.92.0-1.9-1.82.9
Delta time to tail flick, vehicle, before/after SA2.93.15.6-2.42.0-2.02.2-2.2-2.3-2.2-2.2-2.12.01.7-1.7-1.92.32.3-1.6-1.1-1.4-1.4-1.1-1.0-0.6-0.71.00.80.5
Delta time to tail flick, test, before/after SA3.03.77.2-2.32.6-2.71.8-2.6-1.9-1.9-2.7-2.61.92.6-2.5-1.11.31.8-0.7-0.4-2.3-2.30.1-2.2-1.90.4-0.20.11.8
Tibia length3.39.117.24.2-3.23.2-4.13.84.14.13.13.5-4.0-3.13.13.5-3.8-3.03.02.02.22.22.31.30.71.8-1.8-2.0-0.9
Ambulatory time before self-admin0.31.02.20.8-1.51.5-0.31.10.50.31.41.2-0.3-1.21.0-0.1-0.2-1.4-0.3-0.21.31.3-0.71.41.4-0.90.80.6-1.0
Ambulatory time after self-admin1.62.65.9-0.4-1.31.41.20.4-1.1-1.31.20.81.3-1.11.2-1.81.5-1.1-2.0-1.21.61.7-2.32.12.3-2.42.32.2-1.7
Bone: tissue strength0.30.40.80.8-0.50.5-0.90.70.80.80.60.7-0.8-0.80.80.7-0.4-0.10.60.90.40.40.60.20.00.4-0.4-0.5-0.5
Total heroin consumption1.01.13.2-0.3-0.90.90.80.1-0.4-1.10.70.40.7-0.80.9-1.10.5-1.4-1.31.00.90.9-1.51.31.4-1.41.41.8-1.6
Bone: trabecular number0.81.53.81.00.1-0.2-1.40.41.31.6-0.30.1-1.30.1-0.11.7-1.8-0.01.80.4-0.6-0.61.9-1.1-1.41.8-1.7-1.91.4
Bone: trabecular spacing1.01.43.8-0.8-0.40.41.3-0.2-1.1-1.40.40.11.2-0.20.2-1.61.5-0.4-1.8-0.40.80.8-2.01.31.5-1.91.81.9-1.3
Bone: trabecular thickness0.60.81.81.1-0.50.5-1.30.81.21.30.40.7-1.3-0.60.71.3-1.4-0.41.30.60.10.11.2-0.2-0.41.1-1.1-1.00.3
Bone: trabecular tissue density0.50.92.1-0.2-0.80.80.70.3-0.3-0.60.80.50.7-0.70.6-1.00.7-0.9-1.20.71.11.1-1.31.31.4-1.51.41.4-1.2
Water consumed over 24 hours0.30.51.3-0.0-0.50.50.30.2-0.5-0.40.60.40.3-0.80.8-0.60.90.4-0.8-0.40.70.7-1.11.01.1-0.90.90.7-1.1
Number of responses in last shaping day0.50.62.9-0.1-0.50.60.40.3-0.5-0.60.60.40.3-0.60.6-0.60.7-0.1-0.91.70.80.8-1.11.01.2-1.11.01.1-1.0