Adra1a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA isoform ratio XM_063274181.1 0.04 0.03 5.4e-03 0.02 0.02 0 0.02 1.5e-02 1.4e-02 2.6e-01 1.8e-02
2 PL alternative polyA XM_063274182.1 0.04 0.03 6.7e-04 0.02 0.02 0.02 0.02 2.6e-03 3.1e-03 1.2e-03 4.2e-03
3 PL alternative polyA XM_006252109.5 0.04 0.03 3.2e-04 0.02 0.02 0.03 0.02 1.5e-03 1.8e-03 3.3e-04 2.9e-03
4 Brain isoform ratio XM_063274181.1 0.22 0.12 1.0e-15 0.17 0.16 0.17 0.16 2.9e-15 3.2e-15 2.4e-15 4.2e-15
5 Brain gene expression Adra1a 0.33 0.12 0.0e+00 0.32 0.37 0.36 0.36 3.9e-30 8.8e-36 2.3e-34 6.7e-35
6 PL mRNA stability Adra1a 0.17 0.09 0.0e+00 0.14 0.15 0.15 0.16 2.1e-15 1.9e-16 9.7e-16 6.9e-17
7 NAcc alternative polyA XM_006252109.5 0.02 0.01 5.6e-03 0.01 0.01 0.01 0.01 6.7e-03 8.5e-03 8.9e-03 2.2e-02
8 IC mRNA stability Adra1a 0.12 0.07 2.5e-04 0.09 0.09 0.07 0.09 2.0e-04 2.1e-04 8.6e-04 1.7e-04
9 NAcc isoform ratio XM_063274181.1 0.02 0.01 4.9e-03 0.02 0.02 0.01 0.01 1.6e-03 1.5e-03 5.8e-03 1.7e-02
10 PL isoform ratio XM_063274181.1 0.03 0.02 3.2e-03 0.02 0.02 0.01 0.01 4.2e-03 7.0e-03 3.1e-02 9.6e-03
11 pVTA gene expression Adra1a 0.08 0.05 4.6e-06 0.08 0.07 0.06 0.06 3.4e-07 3.6e-06 1.8e-05 8.4e-06
12 Adipose gene expression Adra1a 0.06 0.04 3.2e-05 0.04 0.02 0.03 0.04 2.5e-05 1.5e-03 9.3e-05 2.2e-05
13 Brain mRNA stability Adra1a 0.34 0.13 0.0e+00 0.25 0.28 0.27 0.27 3.5e-23 7.9e-26 1.8e-25 5.4e-25
14 Adipose isoform ratio XM_063274181.1 0.04 0.03 3.4e-04 0.03 0.02 0.02 0.02 6.0e-04 1.2e-03 3.9e-03 1.8e-03
15 OFC gene expression Adra1a 0.23 0.14 3.6e-03 0.14 0.02 0.07 0.07 3.2e-04 1.0e-01 8.1e-03 1.0e-02
16 IC intron excision ratio chr15_45097853_45101519 0.11 0.08 9.4e-04 0.03 0.04 0.01 0.02 1.9e-02 8.9e-03 1.1e-01 4.0e-02
17 Brain isoform ratio XM_006252110.5 0.03 0.02 7.1e-03 0.01 0.01 0.02 0.01 2.3e-02 1.4e-02 2.7e-03 1.6e-02
18 IC gene expression Adra1a 0.16 0.1 1.3e-04 0.08 0.09 0.05 0.08 3.1e-04 1.1e-04 4.1e-03 3.7e-04
19 BLA gene expression Adra1a 0.32 0.13 2.0e-12 0.18 0.19 0.18 0.19 1.1e-09 2.8e-10 1.2e-09 3.5e-10
20 IC isoform ratio XM_006252107.5 0.07 0.06 7.9e-03 0.04 0.05 0.03 0.03 7.4e-03 3.5e-03 2.7e-02 3.2e-02
21 NAcc gene expression Adra1a 0.02 0.02 8.3e-04 0 0.02 0.01 0.01 1.7e-01 1.4e-03 2.3e-02 3.1e-02
22 IL gene expression Adra1a 0.49 0.17 5.0e-07 0.08 0.16 0.13 0.12 6.3e-03 1.2e-04 4.8e-04 7.8e-04
23 NAcc mRNA stability Adra1a 0.12 0.07 1.2e-13 0.09 0.09 0.09 0.09 8.7e-14 4.1e-14 1.0e-13 7.8e-14
24 PL intron excision ratio chr15_45097853_45101519 0.03 0.02 5.5e-03 0.02 0 -0 0 3.5e-03 8.6e-02 4.0e-01 9.9e-02
25 PL isoform ratio XM_006252107.5 0.04 0.03 1.2e-03 0.02 0.01 0.01 0.01 1.0e-03 1.5e-02 3.2e-02 1.4e-02
26 PL gene expression Adra1a 0.32 0.16 0.0e+00 0.13 0.22 0.23 0.22 2.9e-14 6.7e-24 1.2e-24 1.3e-23

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.61.02.80.8-0.30.31.10.31.00.31.30.11.10.00.11.31.1-0.51.5-1.1-0.5-0.51.7-1.0-1.21.61.41.6-1.0
Area under the delay curve0.20.20.40.50.5-0.60.40.60.3-0.70.30.60.40.60.60.20.10.20.0-0.10.60.6-0.20.60.6-0.2-0.3-0.20.6
BMI with tail0.20.71.7-1.1-0.80.8-1.1-1.0-1.10.8-1.1-0.8-1.2-0.4-0.6-1.1-1.3-1.0-1.00.1-0.4-0.4-0.8-0.10.1-0.6-0.7-0.70.2
BMI without tail0.51.53.2-1.3-1.71.7-0.9-1.6-1.31.7-0.8-1.6-1.1-1.5-1.8-0.5-1.0-1.7-0.41.1-1.5-1.5-0.2-1.2-1.00.20.20.2-0.8
Body weight0.10.61.90.30.9-0.90.00.60.1-0.80.20.8-0.01.21.0-0.3-0.60.3-0.5-0.91.01.0-0.71.11.1-0.8-0.8-0.61.4
Weight adjusted by age1.32.04.10.71.8-1.80.11.20.5-1.7-0.11.40.01.82.0-0.50.12.0-0.7-2.01.71.7-1.01.81.8-1.2-1.5-1.41.9
Bone surface0.71.36.21.40.6-0.51.51.11.5-0.61.60.91.50.91.01.51.20.11.5-2.50.30.31.5-0.2-0.51.21.11.2-0.2
Bone volume0.71.34.71.40.6-0.61.51.11.5-0.61.60.91.50.80.81.41.30.31.5-2.20.30.31.5-0.2-0.51.21.11.2-0.3
Breakpoint value in progressive ratio session0.20.30.8-0.40.1-0.0-0.7-0.1-0.4-0.1-0.7-0.0-0.70.10.2-0.8-0.70.0-0.7-0.20.40.4-0.50.40.4-0.7-0.7-0.90.5
Number of licking bursts0.30.61.0-0.9-1.00.9-0.7-0.9-0.80.9-0.6-1.0-0.7-1.0-1.0-0.5-0.7-1.0-0.30.9-0.8-0.8-0.1-0.7-0.6-0.0-0.10.3-0.8
Context. condit. distance diff. score5.66.813.4-2.5-3.73.6-1.5-3.1-2.23.5-1.5-3.3-1.6-3.5-3.6-0.5-1.1-3.4-0.12.6-3.4-3.40.4-3.1-2.81.21.11.1-3.0
Locomotion velocity, session 10.30.30.90.40.8-0.80.10.60.4-0.7-0.10.70.10.70.7-0.20.31.0-0.1-0.70.80.8-0.10.60.5-0.4-0.4-0.60.5
Locomotion distance, session 11.72.24.31.92.0-2.01.42.01.6-1.91.22.01.42.12.00.91.21.80.8-0.51.71.70.41.41.1-0.00.1-0.31.1
Locomotion velocity, session 21.21.43.01.11.6-1.60.71.41.1-1.50.61.50.81.51.50.30.81.70.2-1.71.51.40.01.21.1-0.4-0.4-0.61.0
Locomotion distance, session 22.33.26.32.12.4-2.31.62.32.0-2.21.52.41.72.52.51.01.52.10.9-1.72.12.00.61.61.2-0.00.1-0.21.4
Locomotion velocity, session 30.91.02.7-1.3-0.80.8-1.4-1.1-1.50.6-1.6-0.9-1.3-0.9-0.8-1.3-1.3-0.6-1.30.5-0.4-0.5-1.30.00.3-0.9-0.9-1.20.1
Locomotion distance, session 30.70.81.5-1.1-1.11.1-0.9-1.2-1.11.1-1.0-1.2-0.9-1.2-1.1-0.6-0.6-0.9-0.50.7-1.0-1.0-0.4-0.7-0.5-0.0-0.1-0.2-0.7
Stereotopy head waving bouts, day 30.50.61.6-0.10.6-0.6-0.50.3-0.4-0.7-0.60.4-0.50.60.6-0.9-0.90.4-0.90.10.90.9-0.91.01.0-1.1-1.1-1.20.9
Stereotopy head waving duration, day 31.21.43.1-0.21.0-1.0-0.80.4-0.6-1.0-1.00.6-0.80.90.9-1.3-1.00.9-1.40.41.31.3-1.61.61.7-1.8-1.7-1.81.5
Locomotion velocity, session 77.27.915.4-2.0-3.93.9-0.8-3.0-1.63.7-0.8-3.3-0.6-3.6-3.70.5-0.3-3.70.92.1-3.9-3.91.5-3.8-3.62.42.32.1-3.4
Locomotion distance, session 75.16.513.6-1.2-3.43.4-0.0-2.2-0.73.20.0-2.70.2-3.1-3.11.20.5-3.21.70.5-3.4-3.52.3-3.7-3.72.82.72.5-3.2
Stereotopy head waving bouts, day 71.31.43.30.31.4-1.4-0.20.90.1-1.4-0.21.1-0.21.31.3-0.7-0.61.3-1.00.51.51.5-1.41.81.8-1.5-1.4-1.41.6
Stereotopy head waving duration, day 71.51.84.1-0.31.1-1.1-0.90.3-0.6-1.0-1.00.6-1.01.01.0-1.4-1.11.1-1.70.61.31.3-2.01.82.0-2.0-1.9-1.91.7
Locomotion velocity, session 80.70.82.3-1.2-0.90.9-1.1-1.1-1.20.9-1.2-1.0-1.0-0.8-0.9-1.0-0.9-0.7-0.91.5-0.7-0.6-0.7-0.3-0.1-0.5-0.5-0.6-0.5
Locomotion distance, session 80.50.71.6-0.3-1.11.10.1-0.7-0.31.00.0-0.80.1-0.9-0.90.40.2-1.00.61.1-1.1-1.10.7-1.1-1.11.00.90.8-1.2
Degree of sensitization distance4.44.510.3-0.1-2.32.31.0-1.10.32.11.0-1.51.1-2.1-2.11.91.1-2.42.2-0.3-2.5-2.52.7-3.0-3.23.02.82.8-2.7
Degree of sensitization stereotypy0.70.71.9-0.00.8-0.8-0.30.4-0.2-0.8-0.40.6-0.40.80.7-0.7-0.60.8-1.00.60.91.0-1.31.31.4-1.2-1.2-1.11.1
Conditioned locomotion0.91.01.9-1.3-1.41.4-1.2-1.3-1.21.3-1.1-1.3-1.1-1.3-1.3-0.8-0.9-1.2-0.50.5-1.0-1.0-0.1-0.9-0.8-0.1-0.1-0.4-0.8
Cocaine response after cond. corrected2.93.56.7-2.6-2.22.2-2.4-2.5-2.42.2-2.4-2.4-2.2-2.2-2.1-1.9-2.1-2.1-1.60.9-1.6-1.6-0.9-1.3-0.9-0.7-0.7-0.9-1.0
Cocaine response after cond. not corrected1.61.93.8-2.0-1.61.6-1.9-1.8-1.71.6-1.8-1.7-1.7-1.6-1.6-1.5-1.4-1.3-1.20.5-1.1-1.1-0.7-0.9-0.7-0.6-0.6-0.8-0.7
Cocaine response before conditioning2.32.75.02.21.9-1.92.12.12.2-1.82.02.01.81.71.61.62.12.11.4-1.41.41.41.10.90.60.60.70.70.7
Saline control response1.21.63.11.71.4-1.41.61.71.6-1.41.51.61.51.61.71.31.31.11.1-1.41.11.10.80.80.50.50.60.30.9
Bone: connectivity density1.01.64.00.4-0.90.90.9-0.20.70.91.1-0.50.9-0.7-0.51.31.2-1.01.6-0.8-1.1-1.12.0-1.7-1.91.91.81.8-1.7
Bone: cortical apparent density0.91.32.7-1.3-1.61.6-1.0-1.5-1.21.6-0.9-1.6-0.8-1.4-1.4-0.4-0.6-1.5-0.30.6-1.5-1.5-0.0-1.3-1.10.40.40.3-0.8
Bone: cortical area0.60.91.71.31.1-1.11.21.21.1-1.11.11.21.31.21.21.00.90.80.7-0.90.80.80.40.70.50.40.40.30.7
Bone: cortical porosity1.21.33.10.51.5-1.50.11.00.5-1.40.11.20.11.31.2-0.50.11.8-0.70.11.51.5-1.01.61.6-1.2-1.2-1.11.3
Bone: cortical porosity1.51.63.41.01.8-1.80.51.40.8-1.70.51.50.51.61.6-0.10.41.8-0.4-0.21.71.7-0.81.71.7-1.0-1.0-0.81.5
Bone: cortical thickness0.10.20.40.60.6-0.60.50.60.5-0.50.50.50.60.60.60.40.50.50.3-0.10.40.40.00.40.40.10.10.10.5
Bone: cortical thickness0.60.71.3-1.0-1.21.1-0.9-1.1-0.91.1-0.8-1.1-0.7-1.1-1.0-0.5-0.5-1.0-0.40.2-1.0-1.0-0.2-0.8-0.60.10.1-0.0-0.6
Bone: cortical tissue density1.11.53.1-1.4-1.81.8-1.1-1.7-1.31.7-1.0-1.7-0.9-1.5-1.5-0.5-0.6-1.6-0.40.7-1.6-1.6-0.1-1.4-1.20.40.40.3-0.9
Condit. Reinf. active minus inactive responses0.70.81.70.81.2-1.20.51.10.6-1.30.51.10.31.11.10.10.11.1-0.1-1.01.21.2-0.31.21.1-0.6-0.6-0.50.9
Condit. Reinf. active-inactive response ratio0.80.92.1-0.90.1-0.1-1.2-0.4-1.0-0.1-1.2-0.2-1.3-0.0-0.0-1.4-1.40.1-1.40.20.50.5-1.30.80.9-1.5-1.5-1.40.6
Condit. Reinf. active responses1.62.03.61.81.8-1.81.61.91.7-1.81.61.81.41.71.61.11.21.70.9-1.51.51.50.61.10.90.20.20.30.8
Condit. Reinf. inactive responses4.15.09.83.12.1-2.13.12.63.1-1.93.12.33.11.91.82.93.12.02.7-1.61.21.12.20.5-0.11.82.01.90.1
Incentive salience index mean1.82.24.51.42.1-2.10.91.81.2-2.10.91.90.82.01.90.30.62.0-0.0-1.42.02.0-0.31.81.7-0.8-0.8-0.61.4
Condit. Reinf. lever presses2.33.26.42.02.5-2.51.52.31.8-2.51.42.31.42.42.40.81.12.30.5-1.72.22.20.11.91.7-0.5-0.4-0.31.6
Condit. Reinf. active minus inactive responses0.20.30.80.60.2-0.20.70.50.7-0.30.60.40.60.30.40.70.90.40.70.40.10.10.7-0.1-0.30.60.60.6-0.3
Condit. Reinf. active-inactive response ratio0.20.21.4-0.6-0.40.4-0.6-0.5-0.60.4-0.6-0.5-0.6-0.4-0.3-0.5-0.1-0.0-0.51.2-0.3-0.3-0.4-0.1-0.0-0.3-0.3-0.4-0.1
Condit. Reinf. active responses0.50.71.61.00.2-0.21.20.71.0-0.31.10.51.10.20.31.21.20.21.3-0.1-0.0-0.11.2-0.4-0.61.11.11.0-0.6
Condit. Reinf. inactive responses1.11.53.61.40.2-0.21.71.01.5-0.41.60.71.70.20.21.91.40.11.9-1.2-0.0-0.11.9-0.6-1.01.61.71.4-0.8
Condit. Reinf. lever presses1.21.63.01.71.5-1.51.61.71.6-1.61.41.61.51.41.41.21.21.30.9-1.71.21.20.51.00.70.30.30.20.9
Condit. Reinf. lever reinforcers received0.40.61.51.00.3-0.31.20.71.0-0.41.10.61.10.30.41.21.20.31.2-0.00.0-0.01.0-0.2-0.41.01.10.9-0.4
Conditioned reinforcement - actives0.40.71.5-0.2-1.01.00.2-0.6-0.21.00.0-0.70.4-0.9-1.10.60.3-1.00.70.5-1.1-1.10.9-1.2-1.21.01.00.7-1.2
Conditioned reinforcement - inactives1.21.84.81.60.4-0.41.91.01.4-0.51.80.71.9-0.3-0.02.21.9-0.12.10.4-0.2-0.31.7-0.6-0.91.81.91.8-1.1
Conditioned locomotion0.60.74.0-0.6-1.01.0-0.5-0.9-0.90.9-0.4-0.9-0.3-1.1-1.2-0.1-0.5-1.5-0.12.0-1.0-1.0-0.2-0.7-0.60.30.30.2-0.8
Patch foraging indifference point 0 sec4.78.716.74.13.1-3.13.93.84.0-3.03.83.53.93.13.03.43.52.83.0-2.82.32.22.31.30.71.71.81.51.1
Patch foraging indifference point AUC2.02.87.4-2.2-1.71.7-2.2-2.0-2.41.5-2.2-1.8-1.9-1.7-1.6-1.8-2.0-1.5-1.72.7-1.2-1.2-1.6-0.6-0.2-1.0-0.9-1.0-0.8
Delay disc. indifference point, 0s delay1.51.73.11.71.5-1.51.61.71.8-1.51.71.61.51.41.61.31.41.41.2-0.61.21.21.00.70.40.50.60.60.4
Delay disc. indifference point, 16s delay0.10.10.6-0.1-0.40.40.1-0.2-0.20.30.0-0.30.0-0.3-0.40.2-0.1-0.80.10.5-0.4-0.40.1-0.3-0.30.30.10.3-0.2
Delay disc. indifference point, 2s delay1.82.03.91.22.0-2.00.81.71.1-2.00.71.80.71.91.90.10.41.7-0.1-0.72.02.0-0.31.71.6-0.9-1.0-0.81.5
Delay disc. indifference point, 24s delay0.20.20.4-0.5-0.30.2-0.6-0.4-0.60.2-0.6-0.3-0.5-0.3-0.4-0.6-0.6-0.3-0.60.6-0.0-0.1-0.60.10.2-0.5-0.6-0.60.3
Delay disc. indifference point, 4s delay0.60.61.4-0.30.5-0.5-0.50.1-0.3-0.6-0.70.3-0.60.50.5-0.9-0.80.4-1.0-0.10.70.7-1.21.01.1-1.2-1.2-1.21.2
Delay disc. indifference point, 8s delay0.10.10.50.3-0.10.00.50.20.2-0.10.50.10.50.10.20.50.1-0.60.4-0.7-0.1-0.10.2-0.1-0.10.40.20.40.1
Indifference point function ln k0.91.65.81.61.3-1.31.61.51.7-1.21.61.41.51.51.41.31.31.01.2-2.41.01.01.00.50.20.70.60.70.8
Indifference point function log k0.91.65.81.61.3-1.31.61.51.7-1.21.61.41.51.51.41.31.31.01.2-2.41.01.01.00.50.20.70.60.70.8
Patch foraging total patch changes 0 sec4.58.515.94.03.2-3.23.73.73.8-3.13.73.53.73.23.13.23.32.92.7-3.02.42.32.01.60.91.41.51.31.3
Patch foraging total patch changes 12 sec1.01.22.41.51.3-1.31.31.51.3-1.41.31.51.51.21.31.11.01.20.9-0.81.11.00.60.80.60.30.40.20.5
Patch foraging total patch changes 18 sec0.40.61.71.00.4-0.41.10.80.9-0.61.20.61.30.20.31.30.80.21.1-1.20.10.00.8-0.1-0.20.91.10.9-0.4
Patch foraging total patch changes 24 sec1.62.74.72.02.2-2.11.72.11.8-2.21.72.11.62.02.11.21.42.00.8-1.91.81.70.41.51.20.00.20.11.2
Patch foraging total patch changes 6 sec0.40.61.41.11.0-0.91.01.01.0-0.91.00.91.20.60.60.91.01.00.8-0.00.60.60.50.40.20.30.30.30.1
Patch foraging time to switch 0 sec0.10.33.50.3-0.00.00.50.30.6-0.00.50.20.3-0.2-0.00.40.50.10.6-1.90.10.10.9-0.4-0.50.40.40.2-0.3
Patch foraging water rate 0 sec0.30.51.20.51.0-1.00.20.70.3-0.80.20.80.21.00.8-0.10.01.0-0.41.00.90.9-0.71.11.1-0.7-0.6-0.30.8
Patch foraging water rate 12 sec0.30.71.80.71.2-1.10.50.90.5-1.20.51.00.31.31.20.10.00.9-0.1-0.81.11.1-0.31.11.0-0.5-0.4-0.30.9
Patch foraging water rate 18 sec0.71.03.4-0.60.6-0.6-0.8-0.2-0.8-0.3-1.10.1-1.00.60.4-1.2-0.80.7-1.51.10.60.6-1.81.21.5-1.5-1.4-1.41.3
Patch foraging water rate 24 sec0.30.40.8-0.7-0.80.9-0.5-0.9-0.70.9-0.6-0.9-0.4-0.7-0.9-0.2-0.3-0.7-0.30.3-0.9-0.9-0.3-0.6-0.40.20.30.1-0.3
Patch foraging water rate 6 sec1.21.74.10.71.8-1.80.01.20.2-1.60.11.40.11.71.6-0.5-0.41.5-0.90.31.71.7-1.32.02.0-1.4-1.2-1.11.5
Seeking ratio, delayed vs. immediate footshock1.41.83.71.91.3-1.31.91.71.8-1.21.81.61.81.61.41.61.50.81.4-0.61.00.91.10.50.20.90.71.10.2
Distance traveled before self-admin1.31.73.80.51.7-1.7-0.21.10.2-1.7-0.21.3-0.11.51.4-0.7-0.31.5-0.9-0.41.81.8-1.31.91.9-1.6-1.5-1.41.7
Distance traveled after self-admin1.11.43.1-0.31.0-1.0-0.90.3-0.8-0.9-1.00.6-1.00.81.0-1.4-1.10.8-1.50.91.21.2-1.71.51.7-1.8-1.7-1.51.2
Extensor digitorum longus weight5.521.653.1-3.31.7-1.7-5.2-0.9-4.0-1.6-5.10.2-5.11.61.4-6.6-5.61.8-6.91.93.23.3-7.24.95.8-7.3-7.3-7.25.1
Bone: elastic displacement1.31.53.01.61.5-1.51.31.71.5-1.61.61.71.31.71.70.90.71.00.8-1.01.41.40.51.10.80.10.10.40.9
Bone: elastic work3.24.27.42.62.7-2.62.22.72.4-2.62.22.72.32.72.71.61.72.31.2-1.42.22.20.71.81.40.20.30.41.4
Bone: endosteal estimation0.30.62.31.00.7-0.70.90.90.9-0.70.80.90.90.90.90.80.70.40.7-1.50.60.60.60.30.10.40.40.40.3
Bone: endosteal perimeter0.81.73.11.71.6-1.51.51.71.6-1.51.41.61.41.61.71.11.21.21.0-1.81.31.30.80.90.60.30.30.30.7
Epididymis fat weight0.20.82.20.7-0.20.31.00.20.80.31.2-0.01.1-0.1-0.11.31.1-0.41.3-0.6-0.6-0.61.3-0.9-1.11.41.31.5-0.8
Delta time in closed arm before/after self-admin1.00.92.60.9-0.20.21.20.40.80.11.20.11.3-0.2-0.41.51.2-0.61.50.5-0.5-0.61.3-0.8-1.01.41.61.5-1.0
Delta time in open arm before/after self-admin0.10.10.4-0.20.0-0.0-0.2-0.1-0.3-0.0-0.5-0.0-0.40.10.0-0.4-0.40.0-0.40.00.10.2-0.40.20.3-0.4-0.6-0.60.3
Diff in mean of infusions in LGA sessions0.70.82.40.51.2-1.2-0.00.80.5-1.10.11.00.21.01.2-0.30.21.5-0.4-0.21.21.2-0.51.21.1-0.8-0.9-1.01.0
Delay discount exponential model param0.30.30.8-0.3-0.60.6-0.1-0.5-0.10.7-0.0-0.6-0.1-0.7-0.60.10.3-0.20.30.0-0.7-0.70.6-0.8-0.90.60.60.6-0.9
Extinction: sum of active levers before priming0.70.82.11.00.1-0.21.20.51.2-0.01.30.31.30.20.21.41.40.41.3-0.5-0.3-0.31.2-0.6-0.71.31.21.2-0.6
Active lever presses in extinction session 61.01.02.4-0.8-1.31.3-0.4-1.2-0.71.6-0.5-1.3-0.3-1.4-1.50.0-0.1-0.80.20.6-1.4-1.40.3-1.3-1.20.70.70.6-1.3
Bone: final force0.20.40.90.80.7-0.70.70.80.6-0.80.60.80.60.90.90.40.30.40.3-0.90.70.70.20.50.40.10.00.10.6
Bone: final moment0.71.12.11.31.2-1.21.21.31.1-1.21.11.31.11.41.40.80.70.80.7-1.41.01.00.40.80.60.20.20.30.9
Food consumed during 24 hour testing period0.81.23.11.50.9-0.91.71.11.3-0.81.71.01.61.11.11.61.30.51.2-0.50.30.30.60.30.21.01.01.30.4
Glucose0.81.23.3-1.3-1.51.6-1.0-1.5-1.31.6-0.8-1.5-0.9-1.2-1.1-0.5-1.0-1.8-0.5-0.2-1.4-1.4-0.4-1.0-0.80.30.20.0-0.4
Heart weight0.60.92.30.7-0.40.41.10.20.80.31.2-0.01.2-0.2-0.31.41.0-0.51.40.3-0.7-0.71.3-1.0-1.11.51.41.5-1.0
Delay discount hyperbolic model param0.40.41.0-0.4-0.80.8-0.2-0.6-0.20.9-0.1-0.7-0.1-0.8-0.80.10.2-0.40.40.1-0.9-0.90.6-1.0-1.00.70.70.6-1.0
Intermittent access intake day 1-15 change0.40.81.90.1-0.70.70.4-0.40.40.80.6-0.50.6-0.8-0.40.90.8-0.31.01.1-1.0-1.11.0-1.2-1.21.31.31.4-1.2
Intermittent access intake escalation0.40.72.00.2-0.50.60.5-0.30.50.70.7-0.40.8-0.7-0.40.90.9-0.11.01.4-0.9-0.91.0-1.0-1.11.31.21.4-1.2
Intermittent access intake escalation 20.50.51.6-0.1-0.70.70.2-0.50.10.80.3-0.60.4-0.7-0.40.60.5-0.50.61.3-1.0-1.00.6-0.9-0.91.01.01.1-0.9
Intermitt. access day 1 inactive lever presses0.10.52.4-0.6-1.21.1-0.4-0.7-0.50.9-0.3-0.8-0.4-0.9-0.9-0.2-0.6-1.60.10.3-0.7-0.70.4-0.9-0.90.30.10.3-0.7
Intermitt. access day 15 inactive lever presses0.30.72.7-0.7-1.11.1-0.5-0.9-1.01.0-0.5-0.9-0.5-1.2-0.9-0.1-0.4-1.3-0.21.7-1.0-1.0-0.4-0.7-0.50.30.30.2-0.7
Intermitt. access escalation Index0.10.10.40.30.3-0.30.40.30.5-0.20.40.30.10.60.40.20.30.30.3-0.70.30.30.40.0-0.10.20.10.50.0
Intermittent access day 1 total infusions0.00.00.40.20.1-0.20.20.2-0.2-0.20.00.20.20.1-0.10.2-0.0-0.30.1-0.70.10.1-0.20.20.3-0.00.1-0.20.0
Intermittent access day 15 total infusions0.50.71.90.0-0.70.80.3-0.40.00.80.4-0.60.6-0.9-0.90.80.6-0.70.80.8-1.0-1.10.7-1.0-1.11.11.21.2-1.4
Intermittent access terminal intake (last 3 days)0.60.71.9-0.5-1.01.0-0.3-0.9-0.61.1-0.2-1.0-0.0-1.4-1.10.30.0-0.90.21.1-1.2-1.30.1-1.0-0.90.60.80.7-1.3
Intermittent access total infusions0.70.82.1-0.2-0.91.00.1-0.6-0.21.00.2-0.80.3-1.2-1.40.60.3-1.10.70.8-1.2-1.20.6-1.1-1.10.91.11.0-1.4
Intermittent access day 1 locomotion0.40.61.31.20.8-0.81.01.10.7-0.91.01.01.10.80.50.90.6-0.00.8-0.90.70.70.40.50.30.30.50.20.2
Intermittent access day 15 total locomotion0.30.52.4-0.4-1.01.0-0.2-0.7-0.70.8-0.1-0.8-0.0-0.9-1.00.2-0.4-1.60.11.0-1.0-1.0-0.1-0.7-0.60.50.50.4-0.6
Intermittent access total locomotion0.10.10.50.4-0.00.00.30.20.1-0.10.50.20.5-0.1-0.40.50.1-0.70.40.5-0.1-0.10.2-0.0-0.10.30.40.3-0.3
Intermittent access standard deviation0.10.32.3-0.4-0.50.5-0.4-0.6-0.70.6-0.3-0.6-0.2-0.4-0.2-0.1-0.2-0.4-0.41.5-0.7-0.7-0.7-0.20.10.10.10.2-0.2
Left kidney weight0.31.32.71.51.5-1.41.51.41.3-1.21.71.41.41.51.31.21.21.20.80.30.90.90.20.90.80.40.40.70.7
Right kidney weight0.94.07.32.72.5-2.52.52.62.4-2.32.62.52.52.52.31.92.02.21.5-1.11.81.80.81.51.20.50.50.81.2
Cocaine induced anxiety1.82.65.32.02.1-2.11.52.21.5-2.31.52.31.52.02.00.90.80.90.6-1.92.12.10.21.81.5-0.4-0.3-0.31.5
Post-drug Anxiety3.13.36.82.61.8-1.82.52.42.4-2.02.62.22.41.81.92.01.70.61.9-1.91.51.51.60.80.41.01.01.30.7
Baseline Anxiety0.70.92.50.0-0.90.90.5-0.40.40.90.7-0.60.3-0.7-0.70.80.6-0.51.00.8-1.1-1.01.2-1.3-1.41.31.31.6-1.2
Tail length0.52.15.72.00.9-0.92.31.51.9-1.02.41.32.20.90.82.21.70.52.0-1.10.40.41.6-0.1-0.41.61.51.8-0.1
Length with tail0.73.05.22.22.1-2.11.92.22.1-2.12.12.22.02.22.21.31.21.51.1-2.31.81.80.81.31.00.20.10.61.2
Length without tail1.13.67.30.82.2-2.2-0.01.60.5-2.30.11.9-0.12.52.7-0.9-0.81.7-1.2-2.72.52.6-1.42.62.5-1.9-2.1-1.72.7
Times rat made contact with spout0.50.61.80.1-0.60.70.6-0.40.20.70.6-0.50.5-0.5-0.50.90.6-0.70.80.9-1.0-1.00.7-1.0-1.01.21.21.3-0.9
Lifetime Intake0.40.51.4-0.2-0.70.70.1-0.5-0.30.80.1-0.60.3-1.0-1.20.50.2-1.00.50.9-0.9-1.00.3-0.8-0.80.70.80.7-1.2
Liver weight, left1.32.25.70.92.0-1.90.41.30.7-1.60.31.60.22.42.2-0.30.01.5-0.7-1.91.81.8-1.01.91.9-1.1-1.2-1.22.3
Liver weight, right0.81.44.3-1.5-0.80.8-1.6-1.3-1.70.8-1.5-1.0-1.7-0.1-0.2-1.6-2.1-1.5-1.7-0.1-0.4-0.3-1.60.20.5-1.1-1.3-1.21.0
Locomotor activity4.97.615.82.74.0-3.91.93.42.4-3.82.03.61.53.63.70.61.23.80.2-1.43.73.7-0.53.43.0-1.4-1.4-0.92.7
Locomotor testing distance4.78.414.93.73.7-3.73.23.93.7-3.53.33.82.93.53.52.22.83.62.0-2.23.13.11.52.21.60.40.40.71.5
Locomotor testing rearing5.711.420.34.44.2-4.13.84.54.3-4.13.84.43.64.14.22.83.33.82.5-3.03.53.51.92.41.70.70.80.81.8
Locomotion in novel chamber0.20.30.80.5-0.00.00.90.20.70.00.80.10.4-0.1-0.20.90.70.20.8-0.1-0.4-0.30.7-0.4-0.50.80.70.8-0.5
Locomotion in novel chamber post-restriction0.40.75.7-0.5-0.10.1-0.6-0.2-1.1-0.3-0.8-0.0-0.80.10.2-0.9-1.2-0.6-1.02.40.30.3-1.30.70.9-1.0-1.0-0.80.4
Fecal boli incidents, locomotor time 10.10.20.70.10.5-0.5-0.00.3-0.1-0.5-0.00.30.10.50.5-0.1-0.20.1-0.3-0.80.40.4-0.50.60.6-0.4-0.2-0.40.8
Change in fecal boli incidents, locomotor task1.11.13.3-1.4-1.11.1-1.3-1.1-1.31.0-1.0-1.0-1.5-0.7-0.8-1.4-1.8-1.6-1.1-0.2-0.4-0.3-0.6-0.3-0.1-0.8-1.1-0.70.1
Time >=10cm from walls, locomotor time 11.11.12.71.30.5-0.51.60.91.6-0.41.60.71.20.70.71.51.61.01.5-0.7-0.00.11.4-0.4-0.61.31.11.4-0.1
Bouts of movement, locomotor time 11.72.011.2-1.5-0.00.1-2.0-1.0-1.30.5-1.6-0.7-1.7-0.3-0.3-2.1-1.50.7-2.03.40.20.3-1.80.71.0-1.9-1.7-1.50.2
Total resting periods, locomotor time 12.62.912.2-2.2-0.90.9-2.5-1.6-2.01.1-2.1-1.3-2.2-1.0-1.0-2.5-2.1-0.3-2.33.5-0.4-0.3-2.00.20.6-1.8-1.8-1.6-0.0
Rest time, locomotor task time 12.32.85.6-2.3-1.71.7-2.4-2.1-2.31.6-2.3-1.8-2.0-1.4-1.4-2.1-2.2-1.6-1.91.8-1.1-1.1-1.5-0.5-0.2-1.1-1.2-1.2-0.3
Distance moved, locomotor task time 11.01.54.91.50.8-0.71.81.21.6-0.51.60.91.70.60.61.71.81.01.7-2.20.30.31.5-0.2-0.51.31.11.2-0.2
Vertical activity count, locomotor time 11.43.36.22.12.5-2.51.72.31.8-2.21.42.31.42.32.31.01.42.40.7-2.32.12.10.21.81.5-0.3-0.2-0.41.7
Time >=10cm from walls, locomotor time 20.20.21.2-0.3-0.20.2-0.4-0.2-0.40.0-0.5-0.1-0.50.30.3-0.6-0.7-0.4-0.6-1.10.20.2-0.40.30.3-0.5-0.7-0.61.0
Bouts of movement, locomotor time 21.62.66.5-2.2-0.70.7-2.5-1.6-2.01.0-2.3-1.3-2.3-0.9-0.9-2.5-2.2-0.2-2.41.1-0.2-0.2-2.00.30.7-1.9-2.0-1.70.4
Total resting periods, locomotor time 22.03.68.6-2.6-1.11.1-2.9-2.1-2.41.4-2.6-1.7-2.7-1.3-1.3-2.8-2.5-0.6-2.71.7-0.6-0.6-2.30.10.6-2.0-2.1-1.80.3
Rest time, locomotor task time 23.03.98.0-2.6-2.01.9-2.5-2.5-2.72.0-2.3-2.3-2.2-2.0-1.9-2.1-2.2-1.7-2.12.8-1.7-1.6-2.1-0.7-0.1-1.1-1.2-1.1-0.3
Distance moved, locomotor task time 23.03.616.22.41.4-1.42.62.02.5-1.42.21.82.41.61.62.32.41.32.2-4.00.90.92.00.2-0.31.61.41.40.4
Vertical activity count, locomotor time 22.73.711.82.32.4-2.41.82.52.0-2.41.62.51.62.52.51.21.51.90.9-3.42.22.20.61.71.3-0.10.1-0.11.8
Light reinforcement 10.92.36.10.5-1.21.21.2-0.40.71.41.4-0.71.1-0.7-0.51.81.7-1.21.8-0.8-1.7-1.71.9-1.9-2.02.52.32.3-1.6
Light reinforcement 22.23.47.5-1.7-2.62.5-1.0-2.2-1.52.7-0.8-2.3-0.8-2.3-2.3-0.2-0.7-2.70.01.6-2.5-2.50.3-2.2-2.01.11.01.2-2.0
Bone: marrow area0.30.62.41.10.7-0.71.00.91.0-0.70.90.91.00.90.90.90.80.40.9-1.50.50.50.80.20.00.60.60.50.3
Bone: maximum diameter0.10.20.60.30.6-0.60.10.40.0-0.60.10.50.20.70.8-0.10.00.5-0.3-0.10.50.5-0.50.70.7-0.4-0.4-0.40.7
Bone: maximum force0.61.12.71.11.4-1.30.81.30.8-1.40.71.40.81.61.60.40.30.90.1-1.41.31.3-0.11.21.1-0.3-0.4-0.31.3
Bone: maximum moment1.22.24.71.71.9-1.91.41.91.4-1.91.31.91.42.12.20.90.81.30.6-1.91.71.70.21.51.2-0.1-0.1-0.11.5
Mean time between licks in bursts0.61.53.91.1-0.20.11.50.61.3-0.11.60.31.5-0.1-0.11.71.3-0.51.8-1.9-0.3-0.32.0-1.0-1.31.61.61.9-1.3
Mean num. licks in bursts0.30.41.10.90.5-0.40.90.60.8-0.30.90.51.00.60.61.01.00.50.8-0.20.0-0.00.50.0-0.10.80.90.50.1
Cd content in liver1.71.93.90.81.7-1.70.21.30.4-1.80.11.50.21.61.6-0.4-0.21.3-0.7-1.01.91.9-1.02.01.9-1.4-1.3-1.52.0
Co content in liver2.42.87.3-1.9-0.60.6-2.3-1.2-2.30.4-2.4-0.9-2.3-0.4-0.4-2.5-2.7-1.1-2.40.80.20.2-2.30.81.2-2.1-2.2-2.21.1
Cu content in liver0.50.61.9-0.9-0.60.6-1.0-0.7-1.10.3-0.9-0.5-1.0-0.4-0.4-1.0-1.4-1.1-1.10.5-0.1-0.1-1.10.30.5-0.9-0.8-0.90.6
Fe content in liver0.91.12.90.9-0.20.21.30.41.10.21.30.11.3-0.2-0.21.51.4-0.11.6-0.8-0.5-0.61.7-1.0-1.21.61.71.5-1.0
K content in liver1.01.02.5-0.5-1.31.30.1-0.8-0.21.20.2-1.0-0.1-1.3-1.30.40.1-1.00.60.2-1.3-1.30.8-1.4-1.41.00.91.0-1.6
Mg content in liver0.90.92.20.3-0.80.80.8-0.20.40.70.8-0.40.8-0.7-0.71.20.7-1.01.20.2-1.0-1.01.2-1.2-1.31.51.41.4-1.3
Mn content in liver1.11.33.11.20.0-0.11.70.71.3-0.11.60.51.5-0.0-0.01.81.50.11.7-0.2-0.3-0.31.6-0.7-1.01.61.61.6-1.0
Na content in liver2.52.75.41.32.3-2.30.61.80.9-2.10.62.00.52.32.3-0.10.42.2-0.50.12.12.2-1.12.32.2-1.3-1.2-1.12.1
Rb content in liver0.10.10.4-0.2-0.50.4-0.0-0.3-0.00.40.1-0.40.0-0.6-0.60.20.1-0.20.2-0.3-0.5-0.50.3-0.5-0.50.30.30.4-0.6
Se content in liver3.03.56.92.62.0-2.02.52.62.4-2.32.42.52.32.02.01.91.71.31.7-2.01.91.81.31.20.80.60.70.60.8
Sr content in liver0.10.10.30.30.1-0.20.20.40.1-0.30.20.40.20.30.30.1-0.2-0.50.10.20.30.40.10.20.2-0.1-0.0-0.10.2
Zn content in liver0.40.41.01.00.5-0.61.00.90.8-0.80.90.90.90.60.60.80.4-0.10.7-1.00.60.60.60.30.10.30.40.20.3
Bone: minimum diameter1.01.93.71.71.8-1.81.41.81.4-1.81.31.81.41.91.91.00.81.20.7-1.41.51.50.21.31.10.00.10.11.3
Time in familiar zone, hab. session 10.20.21.8-0.2-0.60.6-0.1-0.4-0.20.5-0.1-0.4-0.1-0.4-0.40.0-0.2-0.70.21.3-0.5-0.50.3-0.5-0.50.30.30.2-0.4
Time in novel zone, hab. session 11.01.02.4-1.2-0.20.2-1.4-0.8-1.20.3-1.4-0.6-1.4-0.3-0.3-1.4-1.3-0.1-1.5-0.20.00.1-1.50.50.8-1.3-1.3-1.30.7
Total zone transitions, hab. session 10.50.71.81.01.2-1.10.61.10.7-1.10.61.10.71.31.30.30.30.80.2-0.01.01.0-0.11.00.9-0.2-0.2-0.20.9
Total locomotion distance, hab. session 11.01.42.51.61.6-1.51.31.61.5-1.51.21.61.31.51.51.01.31.50.9-0.21.21.20.60.90.60.20.30.20.7
Locomotion velocity, hab. session 12.23.15.52.32.2-2.22.02.32.3-2.11.92.22.12.12.11.62.12.21.4-0.71.71.71.01.20.80.50.60.50.8
Time in familiar zone, hab. session 22.12.24.4-2.1-1.71.7-2.0-1.9-1.91.7-1.9-1.8-2.0-1.6-1.4-1.8-1.8-1.6-1.41.3-1.1-1.0-0.7-0.9-0.6-0.8-0.9-0.5-0.8
Time in novel zone, hab. session 21.21.22.11.51.4-1.41.31.41.3-1.31.21.31.31.21.11.11.31.40.8-1.21.00.90.40.80.60.30.50.20.7
Total zone transitions, hab. session 21.72.14.30.91.9-1.90.11.50.5-1.9-0.01.70.21.81.8-0.5-0.21.8-0.7-0.82.12.0-1.02.12.0-1.5-1.3-1.51.9
Total locomotion distance, hab. session 20.70.92.00.81.4-1.40.31.10.7-1.30.11.20.41.21.2-0.00.31.4-0.1-0.41.41.3-0.31.31.1-0.7-0.6-0.81.0
Locomotion velocity, hab. session 21.11.53.00.91.7-1.70.31.40.7-1.70.11.50.41.51.6-0.20.21.7-0.3-0.41.71.7-0.61.61.5-1.0-0.9-1.11.4
Novel to familiar place preference ratio0.70.84.01.10.8-0.81.11.01.2-0.81.00.90.90.90.90.90.80.60.8-2.00.70.60.70.30.10.50.50.50.5
Novelty place preference0.80.83.71.10.9-0.91.11.11.2-0.91.01.00.90.91.00.90.90.80.8-1.90.80.70.80.40.20.40.40.40.5
Time in novel zone, NPP test0.70.83.11.01.1-1.10.91.11.1-1.00.81.10.71.01.10.60.71.00.5-1.81.00.90.50.60.40.10.10.20.7
Total zone transitions, NPP test0.81.22.31.51.3-1.21.31.51.4-1.31.41.41.41.41.41.11.21.11.0-0.61.01.00.80.70.40.40.50.30.5
Total locomotion distance, NPP test2.43.36.92.41.2-1.22.62.02.5-1.22.51.72.61.11.12.52.51.22.5-0.90.70.62.4-0.2-0.71.91.91.8-0.5
Locomotion velocity, NPP test2.12.96.32.31.0-1.02.51.72.3-1.02.41.42.50.91.02.52.40.92.5-1.00.50.42.3-0.3-0.81.92.01.7-0.5
Intraocular pressure0.30.41.20.80.2-0.20.80.60.9-0.30.90.50.80.30.50.90.7-0.01.0-0.70.20.11.1-0.3-0.50.80.80.8-0.4
Delta distance traveled before/after self-admin1.01.12.7-1.3-0.70.7-1.4-1.0-1.60.6-1.6-0.8-1.7-0.5-0.2-1.6-1.6-0.6-1.40.7-0.2-0.2-1.10.10.3-1.1-1.1-1.20.3
Delta ambulatory time before/after self-admin0.81.02.5-1.2-0.30.3-1.4-0.8-1.40.4-1.6-0.6-1.5-0.20.0-1.5-1.5-0.3-1.40.40.10.1-1.20.40.6-1.2-1.2-1.40.5
Parametrial fat weight1.12.67.31.2-0.60.61.80.41.50.61.90.02.0-0.1-0.32.21.9-0.72.4-1.5-0.9-0.92.7-1.7-2.02.52.22.3-1.6
Pavlov. Cond. lever latency0.91.12.2-1.3-1.41.4-1.1-1.3-1.21.3-1.1-1.3-1.2-1.3-1.2-0.8-1.1-1.4-0.51.5-1.0-1.0-0.2-0.9-0.8-0.1-0.1-0.1-0.9
Pavlov. Cond. magazine entry latency0.20.30.80.70.2-0.20.80.40.6-0.20.80.30.90.30.30.90.70.00.7-0.3-0.1-0.10.5-0.1-0.20.70.70.7-0.0
Pavlov. Cond. change in total contacts2.22.34.61.22.1-2.10.71.60.8-2.00.61.80.72.12.00.00.01.6-0.4-1.51.92.0-0.92.02.0-1.1-1.0-1.02.1
Pavlov. Cond. index score0.60.81.51.11.2-1.20.91.10.8-1.10.91.11.01.21.10.70.71.10.4-0.80.90.8-0.00.90.80.00.00.10.8
Pavlov. Cond. latency score0.70.91.61.21.3-1.31.11.21.0-1.21.11.21.21.21.10.91.01.20.6-1.00.90.90.20.80.70.20.20.20.8
Pavlov. Cond. lever contacts0.80.91.51.21.2-1.21.11.21.1-1.11.21.11.21.11.00.91.11.20.7-1.20.80.80.30.70.60.30.30.40.6
Pavlov. Cond. magazine entry number0.20.30.6-0.6-0.80.8-0.4-0.6-0.30.7-0.4-0.6-0.6-0.8-0.7-0.3-0.2-0.6-0.00.2-0.5-0.50.4-0.7-0.70.10.10.1-0.7
Pavlov. Cond. intertrial magazine entries1.31.62.81.61.5-1.51.51.71.6-1.51.31.61.51.31.31.21.31.51.0-1.51.21.20.80.80.50.30.40.30.6
Pavlov. Cond. lever-magazine prob. diff.0.60.71.50.91.2-1.20.71.00.7-1.10.71.00.91.21.10.50.51.00.2-0.60.90.9-0.31.00.9-0.2-0.1-0.10.9
Pavlov. Cond. response bias0.20.20.50.50.7-0.70.40.50.3-0.60.40.50.50.60.60.30.20.50.0-0.40.50.4-0.30.60.6-0.1-0.1-0.10.7
Pavlov. Cond. lever latency1.62.24.4-1.2-2.02.0-0.8-1.7-1.02.1-0.6-1.8-0.6-1.8-1.8-0.1-0.1-1.80.31.7-2.0-2.00.8-2.0-1.91.11.11.1-2.0
Pavlov. Cond. magazine entry latency0.81.01.91.41.1-1.11.31.31.1-1.31.21.21.21.11.11.10.60.70.7-1.30.90.90.30.80.60.30.30.30.8
Pavlov. Cond. change in total contacts1.21.94.50.61.6-1.70.11.20.2-1.8-0.01.4-0.01.61.6-0.6-0.71.2-1.0-1.31.71.8-1.52.12.1-1.5-1.5-1.52.1
Pavlov. Cond. index score1.41.93.91.31.8-1.90.91.60.9-2.00.71.70.71.61.60.30.11.5-0.2-1.31.81.8-0.71.91.8-0.9-0.8-0.81.7
Pavlov. Cond. latency score1.52.04.21.51.9-1.91.11.81.1-2.01.01.81.01.71.70.50.31.60.1-1.51.81.8-0.51.81.7-0.7-0.6-0.61.6
Pavlov. Cond. lever contacts1.72.34.61.42.0-2.11.01.81.1-2.10.81.90.91.81.80.40.41.8-0.1-1.71.91.9-0.72.01.9-0.9-0.8-0.91.9
Pavlov. Cond. magazine entry number0.70.81.6-1.3-1.01.1-1.3-1.2-1.01.2-1.2-1.2-1.1-1.1-1.1-0.9-0.3-0.4-0.71.0-0.9-0.9-0.3-0.8-0.6-0.2-0.2-0.3-0.7
Pavlov. Cond. intertrial magazine entries2.33.510.01.4-0.40.52.10.61.90.52.00.12.1-0.4-0.42.52.7-0.22.9-0.1-1.0-1.13.2-1.9-2.42.92.92.7-2.1
Pavlov. Cond. lever-magazine prob. diff.1.21.63.41.11.7-1.70.71.50.7-1.80.51.60.51.51.50.1-0.01.4-0.3-1.11.71.7-0.81.81.8-1.0-0.9-0.91.7
Pavlov. Cond. response bias1.72.44.81.52.0-2.11.01.81.1-2.20.91.90.91.91.90.30.21.6-0.1-1.62.02.0-0.72.01.9-0.9-0.8-0.92.0
Time in closed arm before self-admin0.40.61.6-0.9-0.10.1-1.0-0.5-0.80.2-1.3-0.4-0.9-0.1-0.2-1.2-0.90.1-1.1-0.30.10.2-0.90.30.5-1.0-1.2-1.30.5
Time in closed arm after self-admin0.10.10.50.30.1-0.10.30.20.2-0.10.10.20.4-0.0-0.10.30.2-0.20.3-0.70.10.10.4-0.1-0.20.20.1-0.1-0.0
Time in open arm before self-admin0.20.31.00.50.7-0.60.30.60.7-0.50.40.60.40.30.60.30.71.00.4-0.60.50.50.50.20.10.10.20.20.1
Time in open arm after self-admin0.00.00.1-0.10.0-0.0-0.1-0.0-0.00.1-0.2-0.0-0.3-0.1-0.1-0.1-0.10.2-0.10.30.00.0-0.0-0.0-0.0-0.1-0.0-0.0-0.1
Bone: periosteal estimation0.51.02.21.31.0-1.01.21.21.1-1.01.11.21.31.21.21.00.90.70.9-1.50.80.70.60.50.30.50.50.40.5
Bone: periosteal perimeter0.61.12.11.41.2-1.21.21.31.2-1.21.11.31.21.41.40.90.90.80.8-1.31.01.00.60.70.50.40.40.40.6
Bone: post-yield work0.91.43.2-1.2-1.71.7-0.8-1.5-1.21.6-0.8-1.6-0.6-1.5-1.6-0.2-0.7-1.8-0.20.1-1.6-1.6-0.0-1.3-1.10.60.50.4-1.0
Progressive ratio test 1 active lever presses0.70.92.8-1.0-1.31.2-0.7-1.1-1.31.2-1.0-1.1-0.8-1.2-1.3-0.4-0.9-1.7-0.40.1-1.0-1.0-0.4-0.7-0.50.00.0-0.2-0.6
Progressive ratio test 1 breakpoint0.70.92.9-1.1-1.31.3-0.8-1.2-1.31.2-1.0-1.2-0.8-1.1-1.2-0.5-1.0-1.7-0.5-0.1-1.0-1.0-0.5-0.7-0.5-0.0-0.1-0.3-0.5
Progressive ratio test 1 inactive lever presses0.71.03.7-0.4-1.41.4-0.0-0.8-0.31.3-0.1-1.0-0.0-1.0-0.90.4-0.1-1.90.6-1.2-1.2-1.21.0-1.4-1.41.11.00.9-0.9
Progressive ratio test 2 active lever presses0.10.20.4-0.1-0.40.4-0.0-0.4-0.30.40.2-0.40.2-0.5-0.60.40.1-0.60.10.5-0.6-0.6-0.2-0.3-0.20.40.50.4-0.4
Progressive ratio test 2 breakpoint0.10.10.30.0-0.20.20.1-0.2-0.20.20.3-0.20.4-0.3-0.40.50.3-0.40.20.5-0.5-0.5-0.2-0.2-0.10.40.50.5-0.4
Progressive ratio test 2 inactive lever presses0.40.72.0-0.0-0.90.90.3-0.5-0.30.80.3-0.60.5-1.3-1.10.70.2-1.40.70.4-1.0-1.10.5-0.9-0.90.91.00.8-1.0
Incentive Sensitization - Responses0.60.91.91.31.2-1.11.11.11.1-1.11.41.11.41.11.01.21.20.90.80.00.60.60.10.70.60.50.60.60.5
Incentive Sensitization - Breakpoint0.81.02.31.41.2-1.21.21.21.2-1.11.51.11.51.11.01.31.41.00.90.20.60.50.20.60.50.60.80.80.4
Sum of active levers in priming session hrs 5-61.11.02.8-1.1-1.31.3-0.8-1.3-0.51.4-0.4-1.4-0.7-1.7-1.5-0.3-0.2-0.5-0.00.2-1.3-1.30.4-1.4-1.30.50.50.5-1.4
Progressive ratio0.40.61.4-0.10.7-0.8-0.40.3-0.2-0.4-0.40.4-0.50.90.6-0.7-0.41.0-0.91.20.70.7-1.21.11.2-1.0-1.0-1.00.9
Food seeking constrained by brief footshock4.75.811.5-3.3-2.32.3-3.3-3.0-3.12.4-3.1-2.7-3.2-2.5-2.4-2.9-2.7-1.4-2.53.4-1.7-1.6-2.0-0.9-0.4-1.5-1.4-1.7-0.9
Seeking ratio, punishment vs. effort1.11.63.6-1.7-1.51.6-1.4-1.7-1.51.4-1.5-1.7-1.5-1.9-1.7-1.1-1.1-1.1-0.81.2-1.3-1.3-0.5-1.1-0.8-0.2-0.1-0.3-1.1
Retroperitoneal fat weight0.21.02.80.4-0.70.81.0-0.10.70.61.1-0.30.7-0.4-0.51.10.8-0.91.4-0.9-0.8-0.81.7-1.3-1.41.51.21.5-1.2
Reaction time number correct0.50.91.9-1.3-1.11.1-1.3-1.2-1.11.0-1.2-1.0-1.3-0.6-0.8-1.2-1.4-1.2-1.0-0.0-0.6-0.5-0.5-0.5-0.3-0.5-0.7-0.6-0.1
Reaction time mean minus median0.20.62.00.51.0-1.00.10.80.4-1.00.10.80.00.80.8-0.10.11.0-0.2-1.41.01.0-0.30.90.8-0.6-0.5-0.50.8
Reaction time mean minus median AUC0.10.22.50.20.5-0.50.00.30.3-0.50.10.4-0.10.40.4-0.10.20.7-0.1-1.60.50.5-0.10.40.4-0.3-0.2-0.10.4
Reaction time num false alarms0.40.51.10.90.8-0.80.80.90.8-0.80.60.90.51.01.00.60.90.90.5-1.00.70.70.40.50.30.20.2-0.00.4
Reaction time num false alarms AUC0.30.41.00.80.8-0.70.80.80.6-0.80.50.80.50.91.00.50.90.90.4-0.90.60.60.30.50.40.20.1-0.10.6
Reaction time trials correct on left0.50.91.9-1.3-1.11.1-1.3-1.2-1.11.0-1.2-1.0-1.3-0.6-0.8-1.2-1.4-1.2-1.0-0.0-0.6-0.5-0.5-0.5-0.3-0.5-0.7-0.6-0.1
Reaction time trials on left0.40.81.6-1.3-1.11.1-1.2-1.1-1.11.1-1.2-1.0-1.2-0.7-0.8-1.1-1.2-1.2-0.8-0.1-0.6-0.6-0.4-0.5-0.4-0.4-0.6-0.5-0.2
Reaction time mean0.10.20.4-0.00.5-0.5-0.30.2-0.1-0.5-0.20.3-0.20.20.1-0.4-0.20.6-0.40.20.50.5-0.60.60.6-0.7-0.4-0.50.4
Reaction time mean AUC0.20.40.80.10.7-0.7-0.30.4-0.1-0.7-0.20.5-0.30.60.5-0.5-0.30.7-0.6-0.30.80.8-0.70.90.9-0.9-0.7-0.80.8
Median of all reaction times0.10.10.4-0.20.2-0.2-0.5-0.1-0.3-0.2-0.30.0-0.30.1-0.1-0.5-0.40.2-0.50.60.20.2-0.60.40.5-0.6-0.4-0.40.3
Reaction time omissions0.50.83.60.4-0.30.30.60.00.80.40.7-0.10.7-0.4-0.30.91.30.01.1-1.9-0.5-0.61.4-1.0-1.21.21.21.2-0.9
Reaction time false alarm rate0.40.61.71.10.8-0.81.11.00.9-0.80.90.90.90.70.91.01.31.00.8-0.40.50.40.50.30.20.50.50.30.3
Reaction time premature initiation rate0.60.92.9-0.9-0.10.1-1.1-0.6-1.10.1-0.9-0.4-1.3-0.2-0.2-1.4-1.20.0-1.41.70.20.3-1.40.60.8-1.3-1.3-1.10.3
Reaction time premature initiations0.91.63.9-1.7-0.70.8-1.8-1.2-1.70.8-1.5-1.0-2.0-0.6-0.6-2.0-1.8-0.7-1.81.7-0.2-0.1-1.60.30.6-1.5-1.6-1.30.2
Std. dev. reaction times0.10.20.80.10.6-0.5-0.10.30.1-0.6-0.10.3-0.20.10.1-0.2-0.00.7-0.3-0.90.50.5-0.40.50.5-0.6-0.4-0.40.3
Reaction time trials completed0.40.81.6-1.3-1.11.1-1.2-1.1-1.11.1-1.2-1.0-1.2-0.7-0.8-1.1-1.2-1.2-0.8-0.1-0.6-0.6-0.4-0.5-0.4-0.4-0.6-0.5-0.2
Reaction time trials AUC0.40.71.4-1.2-1.01.0-1.2-1.1-1.01.0-1.1-1.0-1.2-0.6-0.7-1.1-1.2-1.1-0.8-0.1-0.6-0.5-0.4-0.5-0.4-0.4-0.6-0.4-0.2
Run reversals in cocaine runway, females1.01.04.10.8-0.30.31.00.30.60.21.20.11.3-0.5-0.71.51.2-0.51.32.0-0.6-0.70.9-0.7-0.81.31.41.6-1.2
Run reversals in cocaine runway, males1.71.75.4-0.40.5-0.5-1.00.1-1.2-0.6-0.90.4-1.10.90.9-1.3-1.6-0.1-1.71.21.01.0-2.31.72.0-1.9-1.8-1.71.8
Latency to leave start box in cocaine runway1.01.13.7-0.9-0.40.4-1.1-0.5-1.50.2-1.3-0.3-1.3-0.00.2-1.4-1.9-1.4-1.40.10.30.3-1.50.70.9-1.3-1.2-1.51.0
Latency to leave start box in cocaine runway, F1.51.74.2-1.00.0-0.1-1.5-0.4-1.6-0.2-1.7-0.1-1.60.30.5-1.8-1.9-0.5-1.9-0.20.60.7-2.01.21.5-1.9-1.7-2.11.5
Latency to leave start box in cocaine runway, M0.10.11.6-0.1-0.40.30.0-0.1-0.30.2-0.1-0.1-0.1-0.0-0.0-0.1-0.7-1.3-0.10.1-0.00.0-0.0-0.0-0.0-0.0-0.2-0.00.1
Std. dev. time between licks in bursts3.24.38.52.81.9-1.92.72.52.9-1.82.72.22.81.81.82.52.61.52.4-2.91.41.32.30.4-0.21.51.61.6-0.1
Total sessions with >9 infusions0.10.21.3-0.4-0.50.5-0.3-0.4-0.60.4-0.3-0.4-0.2-0.4-0.6-0.2-0.6-1.1-0.20.4-0.3-0.3-0.2-0.2-0.1-0.1-0.1-0.1-0.4
Short access day 1 total inactive lever presses0.30.45.40.60.4-0.40.60.4-0.1-0.40.40.40.8-0.4-0.50.70.5-0.10.22.3-0.0-0.0-0.70.50.60.00.30.1-0.2
Short access day 10 total inactive lever presses0.10.11.5-0.1-0.60.60.0-0.2-0.20.40.1-0.20.1-0.4-0.10.1-0.2-1.20.2-0.1-0.4-0.40.3-0.4-0.40.40.30.3-0.0
Short access day 1 total infusions0.30.41.4-0.6-0.40.4-0.6-0.5-0.90.4-0.7-0.5-0.4-1.0-1.1-0.5-0.7-0.8-0.51.2-0.3-0.3-0.70.00.2-0.6-0.5-0.4-0.5
Short access day 10 total infusions0.40.51.40.51.0-1.00.20.80.1-1.00.10.90.31.00.8-0.1-0.10.4-0.3-0.21.01.0-0.81.21.2-0.7-0.6-0.60.8
Short access total infusions0.10.10.40.20.4-0.40.10.3-0.2-0.40.00.30.20.1-0.10.1-0.1-0.1-0.10.50.30.3-0.50.60.6-0.4-0.2-0.20.0
Short access day 1 locomotion0.60.71.60.51.0-1.10.00.80.1-1.10.00.90.31.01.0-0.2-0.10.5-0.4-0.81.11.1-0.81.21.2-0.8-0.8-0.91.2
Short access day 10 total locomotion0.20.40.91.00.7-0.80.91.00.7-0.90.90.90.90.40.20.70.40.10.60.80.60.60.20.60.40.10.20.00.1
Short access total locomotion0.50.61.30.90.9-1.00.71.10.4-1.10.61.10.81.00.80.40.1-0.10.2-0.31.01.0-0.21.00.9-0.3-0.2-0.40.9
One hour access (0.3 mA shock)0.30.41.10.6-0.00.00.70.20.60.01.00.10.70.2-0.41.00.7-0.30.90.0-0.3-0.40.6-0.4-0.40.81.01.0-0.5
Compulsive drug intake0.60.71.91.00.4-0.41.10.81.2-0.51.30.60.90.70.31.10.90.21.2-1.40.20.21.3-0.3-0.50.90.90.9-0.1
One hour access (shock baseline)0.10.11.3-0.2-0.20.2-0.3-0.3-0.30.3-0.2-0.30.0-0.4-0.7-0.1-0.1-0.1-0.11.1-0.3-0.3-0.4-0.10.0-0.10.0-0.0-0.5
Social response proportion2.22.55.8-1.8-2.22.2-1.3-2.0-1.62.2-1.1-2.1-1.5-2.0-1.9-0.9-1.5-2.4-0.60.9-1.9-1.7-0.1-1.6-1.40.20.10.6-1.4
Social responses2.02.66.70.4-1.51.51.1-0.50.61.41.2-0.81.0-0.9-0.81.61.0-1.82.0-0.4-1.7-1.62.4-2.2-2.42.52.32.6-2.0
Social time1.21.73.51.81.2-1.21.71.51.8-1.11.71.41.81.21.31.61.91.21.4-0.80.70.71.10.40.11.01.00.90.4
Soleus weight0.72.05.0-1.7-0.40.4-2.1-1.2-1.80.5-2.1-0.9-2.0-0.4-0.4-2.2-1.9-0.3-2.10.30.10.1-1.90.60.9-1.9-1.9-2.00.8
Bone: stiffness0.10.20.5-0.10.3-0.3-0.30.1-0.3-0.3-0.40.2-0.30.50.5-0.4-0.40.1-0.5-0.10.40.4-0.60.60.6-0.5-0.6-0.60.7
Tibialis anterior weight3.612.230.5-2.01.7-1.7-3.5-0.2-2.7-1.6-3.50.6-3.51.71.7-4.7-3.81.8-5.01.32.82.8-5.34.04.6-5.4-5.4-5.54.1
Time to tail flick, vehicle, before self-admin0.50.51.80.70.1-0.00.90.40.8-0.20.90.20.8-0.1-0.11.11.40.81.0-0.3-0.3-0.30.9-0.5-0.61.01.10.8-0.7
Time to tail flick, vehicle, after self-admin3.54.611.0-2.9-1.41.5-3.2-2.3-2.91.7-3.3-2.0-3.2-1.2-1.3-3.2-2.9-0.9-2.91.5-0.7-0.6-2.3-0.00.4-2.1-2.4-2.40.3
Time to tail flick, test, before self-admin2.12.26.11.5-0.10.12.10.81.6-0.12.20.52.00.0-0.12.31.8-0.42.20.4-0.5-0.52.1-1.0-1.32.12.22.5-1.3
Time to tail flick, test, after self-admin3.63.88.5-1.0-2.62.6-0.0-1.7-0.42.30.0-2.0-0.2-2.7-2.50.70.3-1.91.2-0.1-2.5-2.51.9-2.9-2.92.01.91.8-2.9
Delta time to tail flick, vehicle, before/after SA3.23.05.6-2.4-2.02.0-2.2-2.2-2.32.2-2.2-2.1-2.0-1.7-1.7-1.9-2.3-2.3-1.61.1-1.4-1.4-1.1-1.0-0.6-0.7-1.0-0.8-0.5
Delta time to tail flick, test, before/after SA3.63.77.2-2.3-2.62.7-1.8-2.6-1.92.7-1.9-2.6-1.9-2.6-2.5-1.1-1.3-1.8-0.70.3-2.3-2.30.1-2.2-1.90.40.2-0.1-1.8
Tibia length3.39.117.24.23.2-3.24.13.84.1-3.14.13.54.03.13.13.53.83.03.0-2.02.22.22.31.30.71.81.82.00.9
Ambulatory time before self-admin0.71.02.20.81.5-1.50.31.10.5-1.40.31.20.31.21.0-0.10.21.4-0.30.41.31.3-0.71.41.4-0.9-0.8-0.61.0
Ambulatory time after self-admin2.22.65.9-0.41.3-1.4-1.20.4-1.1-1.2-1.30.8-1.31.11.2-1.8-1.51.1-2.01.41.61.7-2.32.12.3-2.4-2.3-2.21.7
Bone: tissue strength0.40.40.90.80.5-0.50.90.70.8-0.60.80.70.80.80.80.70.40.10.6-1.00.40.40.60.20.00.40.40.50.5
Total heroin consumption1.01.13.2-0.30.9-0.9-0.80.1-0.4-0.7-1.10.4-0.70.80.9-1.1-0.51.4-1.3-0.80.90.9-1.51.31.4-1.4-1.4-1.81.6
Bone: trabecular number0.91.53.81.0-0.10.21.40.41.30.31.60.11.3-0.1-0.11.71.80.01.8-0.6-0.6-0.61.9-1.1-1.41.81.71.9-1.4
Bone: trabecular spacing1.11.53.8-0.80.4-0.4-1.3-0.2-1.1-0.4-1.40.1-1.20.20.2-1.6-1.50.4-1.80.60.80.8-2.01.31.5-1.9-1.8-1.91.3
Bone: trabecular thickness0.70.81.81.10.5-0.51.30.81.2-0.41.30.71.30.60.71.31.40.41.3-0.70.10.11.2-0.2-0.41.11.11.0-0.3
Bone: trabecular tissue density0.60.92.1-0.20.8-0.8-0.70.3-0.3-0.8-0.60.5-0.70.70.6-1.0-0.70.9-1.2-0.61.11.1-1.31.31.4-1.5-1.4-1.41.2
Water consumed over 24 hours0.40.51.3-0.00.5-0.5-0.30.2-0.5-0.6-0.30.4-0.30.80.8-0.6-0.9-0.4-0.80.60.70.7-1.11.01.1-0.9-0.9-0.71.1
Number of responses in last shaping day0.60.62.6-0.10.5-0.6-0.40.3-0.5-0.6-0.60.4-0.30.60.6-0.6-0.70.1-0.9-1.60.80.8-1.11.01.2-1.1-1.0-1.11.0