Hub : Traits : Tibialis anterior weight : ← →

chr6:50,926,403-53,588,284

Trait: Tibialis anterior weight

Best TWAS P=1.903113e-09 · Best GWAS P=7.646376e-08 conditioned to 0.17419

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Hdac9	alternative TSS	ENSRNOT00000005521	0.06	0.05	top1	1	0.05	1.9e-06	-5.2	5.2	2.4e-07	-0.75	0.25	0.68	FALSE
2	Adipose	Hdac9	alternative TSS	ENSRNOT00000098095	0.06	0.05	top1	1	0.05	2.2e-06	-5.2	-5.2	2.4e-07	0.75	0.24	0.68	FALSE
3	Adipose	Snx13	alternative TSS	ENSRNOT00000084661	0.02	0.00	blup	2147	0.00	1.4e-01	-4.6	5.3	1.3e-07	-0.79	0.33	0.30	FALSE
4	Adipose	Snx13	alternative TSS	ENSRNOT00000084661	0.03	0.01	enet	59	0.01	3.5e-02	-5.3	6.0	2.0e-09	-0.89	0.30	0.52	FALSE
5	Adipose	Snx13	alternative TSS	ENSRNOT00000095510	0.03	0.00	enet	24	0.01	5.0e-02	-5.3	-6.0	1.9e-09	0.74	0.35	0.51	TRUE
6	Brain	Hdac9	alternative polyA	ENSRNOT00000005521	0.06	0.02	lasso	26	0.04	9.1e-05	-5.2	5.2	2.4e-07	-0.56	0.29	0.67	FALSE
7	Brain	Hdac9	alternative polyA	ENSRNOT00000098095	0.05	0.04	top1	1	0.04	1.0e-04	-5.2	-5.2	2.4e-07	0.64	0.09	0.11	FALSE
8	IL	Ankmy2	mRNA stability	ENSRNOG00000005623	0.23	0.06	blup	3066	0.09	4.4e-03	-4.9	-5.3	1.5e-07	0.76	0.51	0.35	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.