Hub : Genes

Tfcp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Tfcp2 0.41 0.19 7.1e-04 0.09 0.07 0.03 0.09 3.8e-03 1.1e-02 8.1e-02 4.7e-03
2 Liver gene expression Tfcp2 0.29 0.17 2.2e-07 0.03 0.05 0.06 0.05 1.0e-04 2.1e-06 3.1e-07 1.1e-06
3 Brain mRNA stability Tfcp2 0.14 0.07 1.1e-13 0.13 0.15 0.15 0.15 2.6e-12 4.1e-14 4.5e-14 4.3e-14
4 IL gene expression Tfcp2 0.43 0.19 6.5e-05 0.22 0.23 0.23 0.24 5.1e-06 3.5e-06 2.7e-06 1.8e-06
5 Adipose mRNA stability Tfcp2 0.03 0.03 5.4e-03 0.01 0.01 0.03 0.01 3.8e-02 1.6e-02 2.6e-04 6.9e-03
6 Brain gene expression Tfcp2 0.27 0.12 8.3e-14 0.12 0.16 0.16 0.16 1.2e-11 1.3e-14 4.0e-15 5.3e-15
7 PL gene expression Tfcp2 0.3 0.15 1.3e-13 0.11 0.12 0.12 0.12 2.6e-12 3.6e-13 1.1e-12 1.4e-12
8 NAcc gene expression Tfcp2 0.08 0.06 1.9e-05 0.03 0.03 0.04 0.03 1.5e-05 8.5e-06 2.3e-06 2.1e-05
9 IC gene expression Tfcp2 0.13 0.09 7.9e-03 0 0.01 -0 0 1.9e-01 1.7e-01 3.6e-01 2.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density2.44.511.1-3.32.4-1.42.50.9-2.72.3-0.80.9
Area under the delay curve0.10.20.6-0.50.3-0.80.10.5-0.20.10.4-0.2
BMI with tail1.45.012.1-3.53.5-3.21.72.2-1.01.3-0.4-0.4
BMI without tail0.52.46.7-2.42.6-1.41.51.6-0.71.3-0.60.2
Body weight2.19.324.1-4.94.7-2.93.12.1-2.42.5-1.50.7
Weight adjusted by age0.72.23.70.8-0.6-1.8-1.31.71.4-1.51.7-1.9
Bone surface3.05.914.3-3.83.4-1.72.81.0-2.52.6-1.21.1
Bone volume2.65.112.2-3.53.0-1.92.61.3-2.52.3-1.00.8
Breakpoint value in progressive ratio session0.20.41.1-1.00.8-0.20.5-0.2-0.70.6-0.70.4
Number of licking bursts0.51.63.01.7-1.70.1-1.4-0.21.7-1.50.9-0.8
Context. condit. distance diff. score0.70.82.3-1.11.50.11.2-0.1-1.00.9-0.20.7
Locomotion velocity, session 11.21.43.41.5-1.81.5-1.3-1.40.1-0.90.30.0
Locomotion distance, session 11.31.74.91.9-2.21.0-1.6-0.90.5-1.20.5-0.5
Locomotion velocity, session 20.30.30.90.3-0.70.8-0.2-0.9-0.7-0.0-0.30.4
Locomotion distance, session 21.42.05.12.2-2.31.3-1.6-1.40.7-1.20.0-0.2
Locomotion velocity, session 31.31.55.01.2-1.02.2-0.2-1.9-0.0-0.0-1.01.0
Locomotion distance, session 32.12.45.6-0.50.12.41.2-1.8-1.91.5-1.31.9
Stereotopy head waving bouts, day 32.52.95.81.8-1.4-1.2-2.01.12.4-2.01.2-1.8
Stereotopy head waving duration, day 30.70.82.51.2-0.7-0.2-1.10.01.6-1.10.0-0.6
Locomotion velocity, session 71.41.54.40.1-0.12.10.7-1.6-0.81.0-1.61.4
Locomotion distance, session 71.72.16.90.5-0.32.60.4-2.3-0.90.8-1.51.7
Stereotopy head waving bouts, day 72.53.05.80.7-0.8-2.2-1.22.41.6-1.61.8-2.2
Stereotopy head waving duration, day 71.61.93.90.5-0.5-2.0-1.01.91.4-1.31.2-1.8
Locomotion velocity, session 80.10.10.40.6-0.30.4-0.2-0.10.2-0.40.2-0.1
Locomotion distance, session 80.40.62.10.6-0.31.30.0-1.4-0.70.1-0.10.7
Degree of sensitization distance0.50.61.30.9-0.3-0.5-1.00.21.1-1.00.4-0.8
Degree of sensitization stereotypy1.82.04.50.4-0.5-2.0-0.82.11.0-1.21.7-1.9
Conditioned locomotion0.20.20.90.2-0.10.60.2-1.0-0.50.3-0.40.6
Cocaine response after cond. corrected0.30.51.21.0-0.6-0.4-0.80.41.1-0.80.2-0.7
Cocaine response after cond. not corrected0.10.20.50.7-0.60.2-0.50.00.6-0.4-0.1-0.2
Cocaine response before conditioning0.80.92.9-0.2-0.21.70.6-1.4-0.80.7-0.71.2
Saline control response0.70.91.6-1.00.70.71.1-0.4-1.31.2-0.91.0
Bone: connectivity density1.62.66.1-2.51.7-0.62.00.1-2.22.0-0.81.1
Bone: cortical apparent density1.82.84.42.1-1.7-0.8-2.11.12.0-1.81.3-1.8
Bone: cortical area2.03.28.4-2.92.5-1.62.01.2-1.71.6-0.90.5
Bone: cortical porosity1.51.62.7-1.31.00.71.4-0.9-1.71.5-1.21.3
Bone: cortical porosity1.61.83.0-1.30.90.91.4-1.1-1.71.6-1.31.4
Bone: cortical thickness0.61.02.7-1.61.4-1.11.00.8-1.00.7-0.40.1
Bone: cortical thickness0.60.72.1-0.80.10.90.7-0.6-1.40.8-0.60.9
Bone: cortical tissue density1.72.74.42.1-1.7-0.7-2.11.02.0-1.81.2-1.7
Condit. Reinf. active minus inactive responses0.00.00.10.20.1-0.1-0.20.1-0.2-0.20.3-0.2
Condit. Reinf. active-inactive response ratio0.50.51.0-0.90.90.10.8-0.2-1.00.9-0.50.6
Condit. Reinf. active responses0.40.51.01.0-0.80.2-0.9-0.30.4-0.90.8-0.6
Condit. Reinf. inactive responses2.02.55.12.2-2.20.5-2.0-0.51.5-1.91.1-1.0
Incentive salience index mean0.20.30.90.1-0.1-0.6-0.40.5-0.0-0.51.0-0.7
Condit. Reinf. lever presses0.71.12.30.2-0.5-1.4-0.91.00.6-1.11.5-1.3
Condit. Reinf. active minus inactive responses0.20.31.1-0.50.6-1.1-0.11.00.2-0.10.1-0.5
Condit. Reinf. active-inactive response ratio0.20.20.7-0.60.8-0.70.10.70.10.1-0.4-0.1
Condit. Reinf. active responses0.10.20.7-0.20.1-0.6-0.20.80.2-0.20.3-0.5
Condit. Reinf. inactive responses0.20.30.70.6-0.90.2-0.50.10.1-0.50.8-0.4
Condit. Reinf. lever presses0.60.91.9-0.80.70.90.9-1.0-0.80.9-1.41.1
Condit. Reinf. lever reinforcers received0.00.00.1-0.20.1-0.1-0.00.20.1-0.0-0.1-0.1
Conditioned reinforcement - actives0.10.41.40.4-0.81.0-0.2-1.20.10.3-0.70.5
Conditioned reinforcement - inactives0.51.33.71.0-1.81.9-0.6-1.7-0.0-0.1-0.40.6
Conditioned locomotion0.40.51.7-0.0-0.30.90.2-1.30.20.4-1.10.8
Patch foraging indifference point 0 sec0.41.05.50.9-1.22.30.0-1.0-0.20.30.20.8
Patch foraging indifference point AUC0.82.06.11.5-2.5-0.1-1.5-0.61.4-1.51.3-1.1
Delay disc. indifference point, 0s delay0.30.30.8-0.80.7-0.90.50.2-0.50.5-0.10.1
Delay disc. indifference point, 16s delay0.30.40.9-0.90.9-0.30.60.4-0.70.6-0.10.3
Delay disc. indifference point, 2s delay2.73.16.50.6-0.4-2.5-1.32.61.3-1.42.0-2.2
Delay disc. indifference point, 24s delay0.10.10.3-0.20.0-0.5-0.20.20.3-0.20.5-0.3
Delay disc. indifference point, 4s delay0.20.20.8-0.70.1-0.90.20.4-0.50.20.3-0.2
Delay disc. indifference point, 8s delay0.40.71.4-1.11.2-0.11.0-0.1-0.91.0-0.60.8
Indifference point function ln k1.03.09.7-2.33.1-1.31.51.6-1.21.6-1.10.5
Indifference point function log k1.03.09.7-2.33.1-1.31.51.6-1.21.6-1.10.5
Patch foraging total patch changes 0 sec0.41.26.30.7-0.92.50.3-1.2-0.40.5-0.11.1
Patch foraging total patch changes 12 sec1.52.06.61.7-2.61.8-1.1-1.50.6-0.91.1-0.0
Patch foraging total patch changes 18 sec0.92.18.21.6-2.91.9-0.9-1.60.5-0.70.70.2
Patch foraging total patch changes 24 sec0.41.24.31.0-2.11.6-0.4-1.3-0.1-0.41.10.3
Patch foraging total patch changes 6 sec1.32.36.52.0-2.52.0-1.1-1.60.5-0.91.20.0
Patch foraging time to switch 0 sec0.31.02.41.5-1.60.7-0.90.20.8-0.91.1-0.6
Patch foraging water rate 0 sec0.51.84.5-2.12.0-1.11.5-0.3-1.11.2-1.30.6
Patch foraging water rate 12 sec0.31.33.0-1.71.1-0.61.4-0.7-1.51.3-0.60.8
Patch foraging water rate 18 sec0.10.10.6-0.10.8-0.30.20.1-0.70.2-0.20.2
Patch foraging water rate 24 sec0.71.02.7-1.41.6-1.41.00.3-0.60.8-0.60.1
Patch foraging water rate 6 sec1.62.36.2-2.51.8-1.41.9-0.1-1.61.5-1.00.6
Seeking ratio, delayed vs. immediate footshock0.00.10.2-0.50.1-0.50.20.1-0.20.20.1-0.0
Distance traveled before self-admin0.30.71.91.1-1.41.1-0.5-0.80.5-0.60.50.0
Distance traveled after self-admin1.22.14.6-0.20.42.11.0-2.1-1.31.0-1.41.8
Extensor digitorum longus weight2.811.031.8-0.90.9-5.6-1.05.52.4-1.83.1-3.9
Bone: elastic displacement1.92.47.41.8-1.32.7-0.7-2.50.1-0.2-0.71.1
Bone: elastic work1.01.43.6-0.20.41.40.6-1.9-0.70.9-1.71.4
Bone: endosteal estimation2.66.314.8-3.93.6-1.62.91.0-2.42.7-1.71.3
Bone: endosteal perimeter1.84.511.6-3.42.8-1.92.41.6-1.82.0-1.10.6
Epididymis fat weight1.57.410.3-2.72.31.82.8-2.8-3.22.7-2.93.0
Delta time in closed arm before/after self-admin0.20.20.4-0.50.60.20.5-0.3-0.50.5-0.20.5
Delta time in open arm before/after self-admin1.31.53.6-0.20.31.91.0-1.7-1.31.0-0.91.6
Diff in mean of infusions in LGA sessions0.20.41.3-0.60.4-1.10.01.0-0.1-0.20.5-0.7
Delay discount exponential model param0.10.20.80.4-0.20.90.0-0.60.10.1-0.50.3
Extinction: sum of active levers before priming0.50.82.6-1.00.7-1.60.21.30.0-0.20.9-0.8
Active lever presses in extinction session 60.80.81.7-1.10.50.50.6-0.8-1.30.7-1.20.8
Bone: final force4.36.916.4-4.03.8-1.73.00.8-2.72.7-1.81.3
Bone: final moment5.28.419.2-4.44.1-1.73.30.7-2.93.0-2.11.5
Food consumed during 24 hour testing period1.02.15.3-1.82.30.01.6-0.8-1.21.5-1.41.3
Glucose0.10.10.30.2-0.20.5-0.2-0.4-0.3-0.30.40.1
Heart weight1.32.13.3-1.81.60.51.7-0.2-1.71.6-1.41.3
Delay discount hyperbolic model param0.20.20.90.2-0.11.00.1-0.70.10.2-0.60.5
Intermittent access intake day 1-15 change0.41.93.3-1.41.20.91.6-1.2-1.81.5-1.11.5
Intermittent access intake escalation0.31.52.7-1.51.30.41.5-0.6-1.61.4-0.81.2
Intermittent access intake escalation 20.61.02.1-1.11.00.51.4-0.5-0.91.2-0.81.0
Intermitt. access day 1 inactive lever presses0.00.41.00.8-0.7-0.1-1.0-0.10.7-0.60.0-0.4
Intermitt. access day 15 inactive lever presses0.00.10.4-0.10.30.20.3-0.2-0.60.3-0.70.3
Intermitt. access escalation Index0.92.74.51.3-1.6-1.5-1.61.22.1-1.81.7-1.9
Intermittent access day 1 total infusions0.20.52.10.7-0.21.2-0.1-0.70.10.2-1.40.6
Intermittent access day 15 total infusions0.20.61.3-0.10.51.10.7-0.6-0.50.7-1.20.9
Intermittent access terminal intake (last 3 days)0.30.51.50.00.41.10.6-0.4-0.10.6-1.20.8
Intermittent access total infusions0.40.51.50.30.21.20.3-0.50.00.5-1.20.8
Intermittent access day 1 locomotion0.40.82.10.3-0.31.40.2-1.20.00.5-1.41.0
Intermittent access day 15 total locomotion0.93.45.2-1.40.62.11.5-2.2-2.11.9-1.92.3
Intermittent access total locomotion1.21.54.50.1-0.42.10.3-1.8-0.50.8-1.51.5
Intermittent access standard deviation0.52.63.8-0.91.41.61.8-1.6-1.41.7-2.02.0
Left kidney weight0.32.68.2-2.91.5-1.32.00.3-2.01.7-0.60.6
Right kidney weight0.85.715.6-3.93.2-2.82.41.9-2.21.8-0.50.2
Cocaine induced anxiety0.61.74.3-2.11.7-0.51.60.3-1.21.4-1.20.8
Post-drug Anxiety2.32.66.4-2.52.0-0.31.9-0.1-1.31.8-1.81.2
Baseline Anxiety0.10.10.3-0.00.1-0.6-0.40.20.6-0.20.2-0.3
Tail length0.31.42.5-1.41.60.61.60.5-1.11.3-1.11.2
Length with tail0.83.48.0-2.82.7-1.02.21.1-1.71.8-1.21.0
Length without tail0.94.512.3-3.53.0-2.12.30.9-2.11.7-0.80.7
Times rat made contact with spout0.30.40.7-0.70.70.40.6-0.6-0.80.5-0.10.6
Lifetime Intake0.81.03.00.40.21.70.4-1.1-0.10.6-1.61.1
Liver weight, left4.17.117.7-4.23.7-1.83.10.8-2.62.7-1.81.2
Liver weight, right2.54.38.1-2.92.8-0.52.30.3-2.32.3-2.01.4
Locomotor activity0.20.31.00.5-1.00.9-0.5-0.3-0.1-0.20.00.1
Locomotor testing distance0.30.72.21.0-1.41.5-0.7-0.60.1-0.30.00.2
Locomotor testing rearing0.20.72.9-0.0-0.21.70.6-0.8-1.00.8-0.41.0
Locomotion in novel chamber1.52.04.9-2.02.2-1.71.41.7-0.40.9-0.6-0.1
Locomotion in novel chamber post-restriction0.30.81.3-0.80.90.40.8-0.8-1.10.8-1.20.9
Fecal boli incidents, locomotor time 10.51.43.6-0.00.41.70.5-1.9-0.90.9-1.41.5
Change in fecal boli incidents, locomotor task0.80.91.30.5-1.2-0.9-1.01.01.0-1.00.7-1.1
Time >=10cm from walls, locomotor time 10.10.20.80.20.00.90.0-0.4-0.10.3-0.40.6
Bouts of movement, locomotor time 10.40.50.80.9-0.9-0.4-0.7-0.30.7-0.70.6-0.6
Total resting periods, locomotor time 10.60.71.91.4-1.30.2-1.0-0.60.7-0.80.3-0.4
Rest time, locomotor task time 10.20.41.11.0-0.80.6-0.6-0.7-0.2-0.4-0.30.0
Distance moved, locomotor task time 10.10.31.50.50.0-0.3-0.40.51.2-0.60.3-0.5
Vertical activity count, locomotor time 10.10.72.0-0.91.1-1.10.51.40.50.20.4-0.5
Time >=10cm from walls, locomotor time 20.10.20.60.40.10.80.2-0.6-0.30.3-0.30.5
Bouts of movement, locomotor time 20.31.12.8-1.31.6-1.50.61.7-0.20.5-0.0-0.3
Total resting periods, locomotor time 20.31.23.8-1.31.3-1.80.42.0-0.10.30.2-0.6
Rest time, locomotor task time 20.20.30.70.8-0.8-0.0-0.8-0.10.2-0.7-0.1-0.4
Distance moved, locomotor task time 20.20.20.70.6-0.0-0.1-0.20.20.8-0.50.7-0.4
Vertical activity count, locomotor time 20.10.20.7-0.30.7-0.30.30.60.00.10.8-0.2
Light reinforcement 10.41.86.41.4-2.50.4-1.3-1.31.4-1.30.6-0.6
Light reinforcement 20.30.62.60.2-1.6-0.4-0.4-0.60.1-0.61.2-0.5
Bone: marrow area2.56.214.5-3.83.5-1.42.90.9-2.52.7-1.71.3
Bone: maximum diameter0.61.23.3-1.81.4-0.91.30.9-1.01.0-0.50.3
Bone: maximum force3.16.115.0-3.93.6-2.72.51.4-2.22.2-1.30.6
Bone: maximum moment4.07.518.0-4.24.0-2.62.91.2-2.52.6-1.70.9
Mean time between licks in bursts0.10.81.51.2-0.70.7-0.8-1.11.0-0.5-1.20.2
Mean num. licks in bursts1.23.26.1-2.12.20.72.0-0.5-2.52.1-1.31.6
Cd content in liver0.10.10.30.30.10.60.1-0.60.50.1-0.30.4
Co content in liver0.20.31.5-0.0-0.3-0.1-0.20.5-0.3-0.41.2-0.4
Cu content in liver0.81.02.1-1.40.90.21.30.3-1.31.3-0.30.8
Fe content in liver0.30.31.10.8-0.71.1-0.1-0.20.6-0.2-0.40.3
K content in liver0.10.10.2-0.1-0.10.20.00.3-0.40.00.4-0.0
Mg content in liver0.10.20.60.0-0.20.5-0.1-0.6-0.80.0-0.20.3
Mn content in liver0.40.51.20.6-0.8-0.5-0.90.10.1-0.81.1-0.7
Na content in liver0.40.41.0-0.90.60.11.00.5-0.90.70.20.4
Rb content in liver0.30.31.60.00.11.30.4-0.6-0.30.4-0.40.7
Se content in liver0.70.82.31.2-1.21.5-0.5-1.20.4-0.5-0.20.3
Sr content in liver0.70.61.3-1.10.9-0.11.1-0.0-0.81.0-0.40.6
Zn content in liver0.50.51.60.2-0.21.30.3-1.2-0.40.4-0.80.9
Bone: minimum diameter1.93.79.0-3.02.7-2.12.01.4-1.31.8-1.30.4
Time in familiar zone, hab. session 10.10.10.40.4-0.1-0.2-0.6-0.30.3-0.60.2-0.3
Time in novel zone, hab. session 10.10.20.60.3-0.3-0.4-0.10.80.6-0.20.2-0.4
Total zone transitions, hab. session 12.43.34.82.0-1.8-1.3-2.10.91.5-2.22.0-2.1
Total locomotion distance, hab. session 10.60.81.91.4-1.20.0-1.3-0.40.5-1.10.4-0.7
Locomotion velocity, hab. session 10.40.61.31.2-1.0-0.0-1.2-0.30.5-0.90.3-0.6
Time in familiar zone, hab. session 20.60.71.9-1.21.4-0.40.8-0.4-0.80.6-0.50.4
Time in novel zone, hab. session 20.80.82.11.5-1.30.4-0.90.41.1-0.70.6-0.5
Total zone transitions, hab. session 20.30.41.01.0-1.00.1-0.7-0.5-0.1-0.70.5-0.4
Total locomotion distance, hab. session 20.30.41.21.1-1.00.6-0.7-0.80.0-0.5-0.20.0
Locomotion velocity, hab. session 20.20.30.80.8-0.80.6-0.4-0.9-0.3-0.2-0.30.2
Novel to familiar place preference ratio0.91.23.2-0.00.2-1.8-0.31.71.0-0.61.2-1.3
Novelty place preference0.81.12.50.20.0-1.6-0.41.51.2-0.71.1-1.2
Time in novel zone, NPP test1.01.22.40.4-0.1-1.5-0.61.51.4-0.91.2-1.3
Total zone transitions, NPP test1.82.78.22.3-2.90.7-1.9-1.00.6-1.81.3-0.8
Total locomotion distance, NPP test1.82.67.52.3-2.71.4-1.7-1.70.6-1.40.5-0.2
Locomotion velocity, NPP test1.31.95.61.9-2.41.3-1.3-1.70.2-1.10.30.0
Intraocular pressure0.81.46.31.4-0.62.5-0.4-1.70.10.1-0.31.0
Delta distance traveled before/after self-admin4.55.07.8-1.91.91.82.2-2.0-2.82.3-2.52.6
Delta ambulatory time before/after self-admin2.74.67.5-1.61.81.82.1-1.9-2.72.2-2.42.5
Parametrial fat weight0.71.77.50.4-0.41.7-0.2-2.7-1.20.2-1.11.2
Pavlov. Cond. lever latency0.60.72.00.20.31.20.5-1.1-0.30.7-1.41.0
Pavlov. Cond. magazine entry latency0.70.93.0-0.50.4-1.6-0.01.70.5-0.30.9-1.0
Pavlov. Cond. change in total contacts1.31.43.8-0.30.2-1.9-0.41.90.4-0.71.6-1.4
Pavlov. Cond. index score1.41.84.9-0.40.0-2.0-0.32.20.5-0.81.8-1.5
Pavlov. Cond. latency score1.21.64.4-0.40.1-1.9-0.32.10.4-0.71.8-1.4
Pavlov. Cond. lever contacts0.60.72.0-0.3-0.2-1.1-0.31.20.1-0.51.4-0.9
Pavlov. Cond. magazine entry number0.50.62.30.5-0.41.3-0.1-1.5-0.30.2-0.80.8
Pavlov. Cond. intertrial magazine entries1.51.84.81.7-1.62.0-1.0-2.20.4-0.6-0.10.5
Pavlov. Cond. lever-magazine prob. diff.1.41.74.4-0.40.1-2.1-0.32.10.5-0.81.7-1.5
Pavlov. Cond. response bias0.30.41.1-0.30.1-1.0-0.11.00.2-0.30.8-0.7
Pavlov. Cond. lever latency0.60.82.4-0.30.5-1.5-0.11.6-0.2-0.11.2-1.0
Pavlov. Cond. magazine entry latency0.50.72.20.2-0.21.20.0-1.50.30.2-1.31.0
Pavlov. Cond. change in total contacts0.30.61.40.0-0.0-1.2-0.51.01.0-0.80.6-0.9
Pavlov. Cond. index score0.30.51.50.3-0.31.10.0-1.20.4-0.0-1.10.8
Pavlov. Cond. latency score0.30.51.30.4-0.41.1-0.0-1.10.6-0.1-1.00.7
Pavlov. Cond. lever contacts0.60.92.60.2-0.31.50.2-1.60.10.2-1.31.1
Pavlov. Cond. magazine entry number0.20.30.90.10.0-0.7-0.10.9-0.2-0.20.9-0.7
Pavlov. Cond. intertrial magazine entries0.91.94.1-0.80.82.01.4-1.3-1.51.6-1.01.7
Pavlov. Cond. lever-magazine prob. diff.0.20.41.00.3-0.30.9-0.1-1.00.5-0.1-0.90.6
Pavlov. Cond. response bias0.70.92.80.0-0.11.40.2-1.70.10.3-1.51.1
Time in closed arm before self-admin0.91.54.20.2-0.1-1.9-0.72.01.0-0.81.2-1.5
Time in closed arm after self-admin1.21.32.40.7-0.4-1.4-1.01.40.8-1.01.6-1.4
Time in open arm before self-admin1.31.52.91.4-1.4-0.5-1.70.51.5-1.40.8-1.3
Time in open arm after self-admin0.10.10.30.3-0.30.6-0.2-0.40.1-0.1-0.30.2
Bone: periosteal estimation3.27.718.8-4.33.9-2.13.21.4-2.52.8-1.71.1
Bone: periosteal perimeter2.24.411.9-3.52.7-2.32.12.0-1.71.8-0.80.3
Bone: post-yield work1.83.06.5-2.52.4-1.32.00.4-1.61.9-1.40.9
Progressive ratio test 1 active lever presses1.22.27.51.7-1.12.7-0.4-2.20.3-0.0-1.41.1
Progressive ratio test 1 breakpoint1.32.37.81.5-1.02.8-0.3-2.30.20.1-1.51.3
Progressive ratio test 1 inactive lever presses0.10.20.50.7-0.70.5-0.7-0.40.3-0.3-0.0-0.0
Progressive ratio test 2 active lever presses0.30.41.50.5-0.31.2-0.0-0.7-0.30.3-0.80.6
Progressive ratio test 2 breakpoint0.20.31.00.5-0.41.0-0.2-0.5-0.10.1-0.60.4
Progressive ratio test 2 inactive lever presses0.41.22.6-0.30.31.40.5-1.1-1.31.0-1.61.3
Incentive Sensitization - Responses0.10.30.8-0.80.2-0.90.10.9-0.80.20.2-0.3
Incentive Sensitization - Breakpoint0.10.30.9-0.70.1-0.90.10.9-0.70.10.3-0.4
Sum of active levers in priming session hrs 5-60.30.20.70.3-0.8-0.2-0.90.00.0-0.60.2-0.5
Progressive ratio0.30.72.01.4-1.40.9-0.9-0.60.4-0.80.3-0.2
Food seeking constrained by brief footshock0.70.92.11.4-1.31.5-0.6-1.10.5-0.6-0.00.2
Seeking ratio, punishment vs. effort0.00.00.2-0.30.4-0.10.30.10.10.2-0.00.1
Retroperitoneal fat weight1.15.013.2-0.30.63.31.1-3.6-2.31.3-2.22.7
Reaction time number correct1.03.76.3-2.42.50.32.5-0.2-2.12.5-1.41.6
Reaction time mean minus median0.10.82.81.4-1.31.7-0.7-0.3-0.1-0.40.50.2
Reaction time mean minus median AUC0.10.82.31.5-1.11.1-0.9-0.20.0-0.70.9-0.2
Reaction time num false alarms0.61.02.81.7-1.10.5-1.40.21.0-1.10.7-0.6
Reaction time num false alarms AUC0.81.94.32.1-1.50.3-1.80.41.6-1.51.0-1.0
Reaction time trials correct on left1.03.76.3-2.42.50.32.5-0.2-2.12.5-1.41.6
Reaction time trials on left1.03.66.0-2.32.40.42.4-0.2-2.12.4-1.41.6
Reaction time mean0.10.20.80.10.30.90.2-0.0-0.40.3-0.70.5
Reaction time mean AUC0.10.20.6-0.10.40.70.30.1-0.50.4-0.60.5
Median of all reaction times0.30.41.3-0.50.90.50.60.1-0.50.6-1.10.6
Reaction time omissions1.22.05.12.3-2.02.1-1.1-1.10.6-0.80.60.1
Reaction time false alarm rate3.44.78.22.9-2.4-0.3-2.80.82.5-2.61.7-1.8
Reaction time premature initiation rate0.71.03.51.0-1.21.9-0.2-1.6-0.1-0.10.20.7
Reaction time premature initiations0.51.63.8-0.30.31.91.3-1.6-1.31.3-0.71.6
Std. dev. reaction times0.31.02.81.7-1.41.5-1.0-0.20.3-0.80.6-0.1
Reaction time trials completed1.03.66.0-2.32.40.42.4-0.2-2.12.4-1.41.6
Reaction time trials AUC1.13.76.8-2.52.60.12.40.1-2.02.4-1.41.5
Run reversals in cocaine runway, females0.91.02.8-1.01.20.21.00.0-1.71.1-0.70.8
Run reversals in cocaine runway, males1.01.11.61.0-0.9-0.6-1.21.31.3-1.01.0-1.2
Latency to leave start box in cocaine runway0.81.12.11.1-0.8-0.8-1.20.61.5-1.20.7-1.1
Latency to leave start box in cocaine runway, F1.62.03.41.8-1.8-0.2-1.80.21.6-1.61.0-1.2
Latency to leave start box in cocaine runway, M0.50.51.4-0.61.1-1.20.61.00.30.0-0.1-0.4
Std. dev. time between licks in bursts0.40.71.71.1-1.31.0-0.6-1.10.4-0.60.10.2
Total sessions with >9 infusions0.60.81.61.3-0.81.3-0.8-1.00.9-0.3-0.90.3
Short access day 1 total inactive lever presses0.20.51.50.8-0.81.2-0.4-0.90.6-0.1-0.60.4
Short access day 10 total inactive lever presses0.00.10.3-0.40.2-0.30.10.60.40.2-0.2-0.0
Short access day 1 total infusions0.71.33.6-0.00.51.70.7-1.3-0.40.9-1.91.3
Short access day 10 total infusions0.30.51.41.0-0.31.2-0.2-0.40.50.0-1.00.4
Short access total infusions1.11.65.30.60.02.30.4-1.6-0.30.7-1.81.4
Short access day 1 locomotion0.10.20.50.3-0.20.7-0.1-0.50.4-0.0-0.60.3
Short access day 10 total locomotion0.10.30.8-0.1-0.00.90.1-0.3-0.10.6-0.90.7
Short access total locomotion0.40.61.70.4-0.41.3-0.1-1.00.50.3-1.20.8
One hour access (0.3 mA shock)0.50.71.7-1.01.3-0.20.90.4-0.90.7-0.80.3
Compulsive drug intake0.30.40.9-0.20.3-0.9-0.60.80.2-0.50.9-0.7
One hour access (shock baseline)0.30.81.5-1.01.10.01.20.2-0.91.0-1.20.6
Social response proportion1.01.21.8-0.81.11.11.1-0.6-1.31.2-1.11.4
Social responses1.01.33.21.8-1.61.0-1.2-0.21.1-1.10.5-0.4
Social time1.11.72.8-1.51.50.51.6-0.2-1.21.5-1.71.3
Soleus weight0.30.92.8-1.71.3-0.71.10.5-1.10.9-0.20.5
Bone: stiffness3.56.415.3-3.93.6-3.52.32.2-1.71.9-0.90.1
Tibialis anterior weight4.114.132.50.30.0-5.6-2.05.73.2-3.04.3-4.6
Time to tail flick, vehicle, before self-admin0.30.31.01.0-0.70.6-0.6-0.40.5-0.40.4-0.1
Time to tail flick, vehicle, after self-admin0.10.30.7-0.10.1-0.8-0.20.80.8-0.2-0.3-0.7
Time to tail flick, test, before self-admin0.50.61.51.0-0.6-0.2-0.80.50.5-0.91.2-0.8
Time to tail flick, test, after self-admin0.30.30.7-0.60.9-0.70.60.7-0.30.4-0.3-0.1
Delta time to tail flick, vehicle, before/after SA0.50.51.3-1.10.9-0.30.80.2-0.30.7-1.10.3
Delta time to tail flick, test, before/after SA0.30.41.3-0.80.8-0.30.70.2-0.20.7-1.10.3
Tibia length3.08.418.5-4.33.8-0.73.50.0-2.73.1-2.82.1
Ambulatory time before self-admin0.30.92.21.2-1.51.4-0.6-1.20.4-0.60.50.2
Ambulatory time after self-admin1.52.45.8-0.20.22.41.0-2.2-1.71.2-1.32.0
Bone: tissue strength0.20.21.0-0.50.8-1.00.10.5-0.20.10.2-0.3
Total heroin consumption0.60.81.7-1.31.00.20.8-0.6-1.10.8-0.80.8
Bone: trabecular number1.83.48.0-2.82.0-0.62.30.0-2.42.2-1.01.3
Bone: trabecular spacing0.71.12.11.5-0.8-0.0-1.30.31.4-1.30.6-1.0
Bone: trabecular thickness0.40.51.3-0.1-0.4-1.1-0.30.9-0.3-0.41.2-0.8
Bone: trabecular tissue density2.54.36.01.7-1.4-2.4-2.31.92.4-2.31.5-2.4
Water consumed over 24 hours1.12.13.6-1.51.41.11.6-1.1-1.91.7-0.91.6
Number of responses in last shaping day0.10.20.60.5-0.3-0.4-0.20.20.8-0.40.2-0.5