Hub : Genes

Tfcp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Tfcp2 0.41 0.19 7.1e-04 0.09 0.07 0.02 0.08 3.8e-03 1.1e-02 9.0e-02 4.9e-03
2 Liver gene expression Tfcp2 0.29 0.17 2.2e-07 0.03 0.05 0.06 0.06 1.0e-04 2.1e-06 2.7e-07 9.0e-07
3 Brain mRNA stability Tfcp2 0.14 0.07 1.1e-13 0.13 0.15 0.15 0.15 2.6e-12 4.1e-14 4.5e-14 4.2e-14
4 IL gene expression Tfcp2 0.43 0.19 6.5e-05 0.22 0.23 0.23 0.24 5.1e-06 3.5e-06 2.7e-06 1.8e-06
5 Adipose mRNA stability Tfcp2 0.03 0.03 5.4e-03 0.01 0.01 0.03 0.02 3.8e-02 1.6e-02 2.6e-04 6.6e-03
6 Brain gene expression Tfcp2 0.27 0.12 8.3e-14 0.12 0.16 0.16 0.16 1.2e-11 1.3e-14 4.0e-15 5.4e-15
7 PL gene expression Tfcp2 0.3 0.15 1.3e-13 0.11 0.12 0.12 0.12 2.6e-12 3.6e-13 8.0e-13 1.3e-12
8 NAcc gene expression Tfcp2 0.08 0.06 1.9e-05 0.03 0.03 0.04 0.03 1.5e-05 8.5e-06 2.7e-06 1.9e-05
9 IC gene expression Tfcp2 0.13 0.09 7.9e-03 0 0.01 -0 0 1.9e-01 1.7e-01 4.2e-01 2.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density2.64.511.13.3-2.5-1.42.5-0.92.72.30.80.9
Area under the delay curve0.10.20.60.5-0.3-0.80.1-0.50.20.1-0.4-0.2
BMI with tail1.55.012.13.5-3.5-3.21.7-2.21.01.30.4-0.4
BMI without tail0.82.46.72.4-2.6-1.41.5-1.60.71.30.60.2
Body weight2.19.324.14.9-4.7-2.93.1-2.12.42.51.50.7
Weight adjusted by age1.42.23.7-0.80.6-1.8-1.3-1.7-1.4-1.5-1.7-1.9
Bone surface3.36.014.33.8-3.4-1.72.8-1.02.52.61.21.1
Bone volume2.95.112.23.5-3.1-1.92.6-1.32.52.31.00.8
Breakpoint value in progressive ratio session0.30.41.11.0-0.9-0.20.50.20.70.60.70.4
Number of licking bursts1.01.63.0-1.71.70.1-1.40.2-1.7-1.5-0.9-0.8
Context. condit. distance diff. score0.70.82.31.1-1.50.11.20.11.00.90.20.7
Locomotion velocity, session 11.31.43.4-1.51.81.5-1.31.4-0.1-0.9-0.30.0
Locomotion distance, session 11.31.74.9-1.92.21.0-1.60.9-0.5-1.2-0.5-0.5
Locomotion velocity, session 20.30.30.9-0.30.60.8-0.20.90.7-0.00.30.4
Locomotion distance, session 21.42.05.1-2.22.31.3-1.61.4-0.7-1.2-0.0-0.2
Locomotion velocity, session 31.31.55.0-1.21.02.2-0.21.90.0-0.01.01.0
Locomotion distance, session 32.22.45.60.5-0.12.41.21.81.91.51.31.9
Stereotopy head waving bouts, day 32.52.95.8-1.81.4-1.2-2.0-1.1-2.4-2.0-1.2-1.8
Stereotopy head waving duration, day 30.70.82.5-1.20.7-0.2-1.1-0.0-1.6-1.1-0.0-0.6
Locomotion velocity, session 71.41.54.4-0.10.12.10.71.60.81.01.61.4
Locomotion distance, session 71.72.16.9-0.50.32.60.42.30.90.81.51.7
Stereotopy head waving bouts, day 72.63.05.8-0.70.8-2.2-1.2-2.4-1.6-1.6-1.8-2.2
Stereotopy head waving duration, day 71.61.93.9-0.50.5-2.0-1.0-1.9-1.4-1.3-1.2-1.8
Locomotion velocity, session 80.10.10.4-0.60.30.4-0.20.1-0.2-0.4-0.2-0.1
Locomotion distance, session 80.40.62.1-0.60.31.30.01.40.70.10.10.7
Degree of sensitization distance0.60.61.3-0.90.3-0.5-1.0-0.2-1.1-1.0-0.4-0.8
Degree of sensitization stereotypy1.92.04.5-0.40.5-2.0-0.8-2.1-1.0-1.2-1.7-1.9
Conditioned locomotion0.20.20.9-0.20.10.60.21.00.50.30.40.6
Cocaine response after cond. corrected0.40.51.2-1.00.6-0.4-0.8-0.4-1.1-0.8-0.2-0.7
Cocaine response after cond. not corrected0.20.20.5-0.70.60.2-0.5-0.0-0.6-0.40.1-0.2
Cocaine response before conditioning0.80.92.90.20.21.70.61.40.80.70.71.2
Saline control response0.70.91.61.0-0.70.71.10.41.31.20.91.0
Bone: connectivity density1.72.66.12.5-1.7-0.62.0-0.12.22.00.81.1
Bone: cortical apparent density2.12.84.4-2.11.7-0.8-2.1-1.1-2.0-1.8-1.3-1.8
Bone: cortical area2.13.28.42.9-2.5-1.62.0-1.21.71.60.90.5
Bone: cortical porosity1.51.62.71.3-1.00.71.40.91.71.51.21.3
Bone: cortical porosity1.61.83.01.3-0.90.91.41.11.71.61.31.4
Bone: cortical thickness0.61.02.71.6-1.4-1.11.0-0.81.00.70.40.1
Bone: cortical thickness0.60.72.10.8-0.10.90.70.61.40.80.60.9
Bone: cortical tissue density2.02.84.4-2.11.7-0.7-2.1-1.0-2.0-1.8-1.2-1.7
Condit. Reinf. active minus inactive responses0.00.00.1-0.2-0.1-0.1-0.2-0.10.2-0.2-0.3-0.2
Condit. Reinf. active-inactive response ratio0.50.51.00.9-0.90.10.80.21.00.90.50.6
Condit. Reinf. active responses0.40.51.0-1.00.80.2-0.90.3-0.4-0.9-0.8-0.6
Condit. Reinf. inactive responses2.12.55.1-2.22.20.5-2.00.5-1.5-1.9-1.1-1.0
Incentive salience index mean0.20.30.9-0.10.1-0.6-0.4-0.50.0-0.5-1.0-0.7
Condit. Reinf. lever presses0.81.12.3-0.20.5-1.4-0.9-1.0-0.6-1.1-1.5-1.3
Condit. Reinf. active minus inactive responses0.30.31.10.5-0.6-1.1-0.1-1.0-0.2-0.1-0.1-0.5
Condit. Reinf. active-inactive response ratio0.20.20.70.6-0.8-0.70.1-0.7-0.10.10.4-0.1
Condit. Reinf. active responses0.10.20.70.2-0.1-0.6-0.2-0.8-0.2-0.2-0.3-0.5
Condit. Reinf. inactive responses0.20.30.7-0.60.90.2-0.5-0.1-0.1-0.5-0.8-0.4
Condit. Reinf. lever presses0.70.91.90.8-0.70.90.91.00.80.91.41.1
Condit. Reinf. lever reinforcers received0.00.00.10.2-0.1-0.1-0.0-0.2-0.1-0.00.1-0.1
Conditioned reinforcement - actives0.30.41.4-0.40.81.0-0.21.2-0.10.30.70.5
Conditioned reinforcement - inactives0.91.33.7-1.01.81.9-0.61.70.0-0.10.40.6
Conditioned locomotion0.40.51.70.00.30.90.21.3-0.20.41.10.8
Patch foraging indifference point 0 sec0.61.05.5-0.91.22.30.01.00.20.3-0.20.8
Patch foraging indifference point AUC1.42.06.0-1.52.5-0.1-1.50.6-1.4-1.5-1.3-1.1
Delay disc. indifference point, 0s delay0.30.30.80.8-0.7-0.90.5-0.20.50.50.10.1
Delay disc. indifference point, 16s delay0.30.40.90.9-0.9-0.30.6-0.40.70.60.10.3
Delay disc. indifference point, 2s delay2.73.16.5-0.60.4-2.5-1.3-2.6-1.3-1.4-2.0-2.2
Delay disc. indifference point, 24s delay0.10.10.30.2-0.0-0.5-0.2-0.2-0.3-0.2-0.5-0.3
Delay disc. indifference point, 4s delay0.20.20.80.7-0.1-0.90.2-0.40.50.2-0.3-0.2
Delay disc. indifference point, 8s delay0.60.71.41.1-1.2-0.11.00.10.91.00.60.8
Indifference point function ln k1.73.09.62.3-3.1-1.31.5-1.61.21.61.10.5
Indifference point function log k1.73.09.62.3-3.1-1.31.5-1.61.21.61.10.5
Patch foraging total patch changes 0 sec0.61.26.3-0.70.92.50.31.20.40.50.11.1
Patch foraging total patch changes 12 sec1.62.06.6-1.72.61.8-1.11.5-0.6-0.9-1.1-0.0
Patch foraging total patch changes 18 sec1.42.18.1-1.62.81.9-0.91.6-0.5-0.7-0.70.2
Patch foraging total patch changes 24 sec0.71.24.3-1.02.11.6-0.41.30.1-0.4-1.10.3
Patch foraging total patch changes 6 sec1.52.36.4-2.02.52.0-1.11.6-0.5-0.9-1.20.0
Patch foraging time to switch 0 sec0.51.02.4-1.51.60.7-0.9-0.2-0.8-0.9-1.1-0.6
Patch foraging water rate 0 sec0.91.84.52.1-2.0-1.11.50.31.11.21.30.6
Patch foraging water rate 12 sec0.61.33.01.7-1.1-0.61.40.71.51.30.60.8
Patch foraging water rate 18 sec0.10.10.60.1-0.8-0.30.2-0.10.70.20.20.2
Patch foraging water rate 24 sec0.71.02.61.4-1.6-1.41.0-0.30.60.80.60.1
Patch foraging water rate 6 sec1.62.36.22.5-1.8-1.41.90.11.61.51.00.6
Seeking ratio, delayed vs. immediate footshock0.10.10.20.5-0.1-0.50.2-0.10.20.2-0.1-0.0
Distance traveled before self-admin0.50.71.9-1.11.41.1-0.50.8-0.5-0.6-0.50.0
Distance traveled after self-admin1.72.14.60.2-0.42.11.02.11.31.01.41.8
Extensor digitorum longus weight2.811.031.80.9-0.9-5.6-1.0-5.5-2.4-1.8-3.1-3.9
Bone: elastic displacement2.02.47.4-1.81.42.7-0.62.5-0.1-0.20.71.1
Bone: elastic work1.01.43.60.2-0.41.40.61.90.70.91.71.4
Bone: endosteal estimation2.96.314.83.9-3.6-1.62.9-1.02.42.71.71.3
Bone: endosteal perimeter2.14.511.63.4-2.8-1.92.4-1.61.82.01.10.6
Epididymis fat weight2.27.410.32.7-2.31.82.82.83.22.72.93.0
Delta time in closed arm before/after self-admin0.20.20.40.5-0.60.20.50.30.50.50.20.5
Delta time in open arm before/after self-admin1.51.53.60.2-0.31.91.01.71.31.00.91.6
Diff in mean of infusions in LGA sessions0.30.41.30.6-0.4-1.10.0-1.00.1-0.2-0.5-0.7
Delay discount exponential model param0.20.20.8-0.40.20.90.00.6-0.10.10.50.3
Extinction: sum of active levers before priming0.70.82.61.0-0.7-1.60.1-1.3-0.0-0.2-0.9-0.8
Active lever presses in extinction session 60.80.81.71.1-0.50.50.60.81.30.71.20.8
Bone: final force4.36.916.44.0-3.8-1.73.0-0.82.72.71.81.3
Bone: final moment5.28.419.24.4-4.1-1.73.3-0.72.93.02.11.5
Food consumed during 24 hour testing period1.52.15.21.8-2.30.01.50.81.21.51.41.3
Glucose0.10.10.3-0.20.20.5-0.20.40.3-0.3-0.40.1
Heart weight1.32.13.31.8-1.60.51.70.21.71.61.41.3
Delay discount hyperbolic model param0.20.20.9-0.20.11.00.10.7-0.10.20.60.5
Intermittent access intake day 1-15 change0.91.93.31.4-1.20.91.61.21.81.51.11.5
Intermittent access intake escalation0.71.52.71.5-1.30.41.50.61.61.40.81.2
Intermittent access intake escalation 20.91.02.11.1-1.00.51.40.50.91.20.81.0
Intermitt. access day 1 inactive lever presses0.10.41.0-0.80.7-0.1-1.00.1-0.7-0.6-0.0-0.4
Intermitt. access day 15 inactive lever presses0.10.10.40.1-0.30.20.30.20.60.30.70.3
Intermitt. access escalation Index1.92.74.5-1.31.6-1.5-1.6-1.2-2.1-1.8-1.7-1.9
Intermittent access day 1 total infusions0.30.52.1-0.70.21.2-0.10.7-0.10.21.40.6
Intermittent access day 15 total infusions0.40.61.30.1-0.51.10.70.60.50.71.20.9
Intermittent access terminal intake (last 3 days)0.40.51.5-0.0-0.41.10.60.40.10.61.20.8
Intermittent access total infusions0.40.51.5-0.3-0.21.20.30.5-0.00.51.20.8
Intermittent access day 1 locomotion0.60.82.1-0.30.31.40.21.2-0.00.51.41.0
Intermittent access day 15 total locomotion1.93.45.21.4-0.62.11.52.22.11.91.92.3
Intermittent access total locomotion1.21.54.5-0.10.42.10.31.80.50.81.51.5
Intermittent access standard deviation1.32.63.80.9-1.41.61.81.61.41.72.02.0
Left kidney weight0.62.68.22.9-1.5-1.32.0-0.32.01.70.60.6
Right kidney weight1.25.715.63.9-3.2-2.82.4-1.92.21.80.50.2
Cocaine induced anxiety1.21.74.32.1-1.7-0.51.6-0.31.21.41.20.8
Post-drug Anxiety2.52.66.42.5-2.0-0.31.90.11.31.81.81.2
Baseline Anxiety0.10.10.30.0-0.1-0.6-0.4-0.2-0.6-0.2-0.2-0.3
Tail length0.41.42.51.4-1.60.61.6-0.51.11.31.11.2
Length with tail0.83.48.02.8-2.7-1.02.2-1.11.71.81.21.0
Length without tail1.44.512.33.5-3.0-2.12.3-0.92.11.70.80.7
Times rat made contact with spout0.30.40.70.7-0.70.40.60.60.80.50.10.6
Lifetime Intake0.81.03.0-0.4-0.21.70.41.10.10.61.61.1
Liver weight, left4.37.117.74.2-3.7-1.83.1-0.82.62.71.81.2
Liver weight, right2.54.38.12.9-2.8-0.52.3-0.32.32.32.01.4
Locomotor activity0.20.30.9-0.51.00.9-0.50.30.1-0.2-0.00.1
Locomotor testing distance0.40.72.2-1.01.41.5-0.70.6-0.1-0.3-0.00.2
Locomotor testing rearing0.40.72.90.00.21.70.60.81.00.80.41.0
Locomotion in novel chamber1.52.04.92.0-2.2-1.71.4-1.70.40.90.6-0.1
Locomotion in novel chamber post-restriction0.50.81.30.8-0.90.40.80.81.10.81.20.9
Fecal boli incidents, locomotor time 11.01.43.60.0-0.41.70.51.90.90.91.41.5
Change in fecal boli incidents, locomotor task0.90.91.3-0.51.1-0.9-1.0-1.0-1.0-1.0-0.7-1.1
Time >=10cm from walls, locomotor time 10.20.20.8-0.2-0.00.90.00.40.10.30.40.6
Bouts of movement, locomotor time 10.40.50.8-0.90.9-0.4-0.70.3-0.7-0.7-0.6-0.6
Total resting periods, locomotor time 10.60.71.9-1.41.30.2-1.00.6-0.7-0.8-0.3-0.4
Rest time, locomotor task time 10.30.41.1-1.00.80.6-0.60.70.2-0.40.30.0
Distance moved, locomotor task time 10.20.31.5-0.50.0-0.3-0.4-0.5-1.2-0.6-0.3-0.5
Vertical activity count, locomotor time 10.30.72.00.9-1.1-1.10.5-1.4-0.50.2-0.4-0.5
Time >=10cm from walls, locomotor time 20.10.20.6-0.4-0.10.80.20.60.30.30.30.5
Bouts of movement, locomotor time 20.71.12.81.3-1.6-1.50.6-1.70.20.50.0-0.3
Total resting periods, locomotor time 20.71.23.81.3-1.3-1.80.4-2.00.10.3-0.2-0.6
Rest time, locomotor task time 20.20.30.7-0.80.8-0.0-0.80.1-0.2-0.70.1-0.4
Distance moved, locomotor task time 20.20.20.7-0.60.0-0.1-0.2-0.2-0.8-0.5-0.7-0.4
Vertical activity count, locomotor time 20.20.20.70.3-0.7-0.30.3-0.6-0.00.1-0.8-0.2
Light reinforcement 10.71.86.3-1.42.50.4-1.31.3-1.4-1.3-0.6-0.6
Light reinforcement 20.40.62.5-0.21.6-0.4-0.40.6-0.1-0.6-1.2-0.5
Bone: marrow area2.96.214.53.8-3.5-1.42.9-0.92.52.71.71.3
Bone: maximum diameter0.71.23.31.8-1.4-0.91.2-0.91.01.00.50.3
Bone: maximum force3.46.115.03.9-3.6-2.72.5-1.42.22.21.30.6
Bone: maximum moment4.37.518.04.2-4.0-2.62.9-1.22.52.61.70.9
Mean time between licks in bursts0.30.81.5-1.20.70.7-0.81.1-1.0-0.51.20.2
Mean num. licks in bursts2.13.26.12.1-2.20.72.00.52.52.11.31.6
Cd content in liver0.10.10.3-0.3-0.10.60.10.6-0.50.10.30.4
Co content in liver0.20.31.50.00.3-0.1-0.2-0.50.3-0.4-1.2-0.4
Cu content in liver0.81.02.11.4-0.90.21.3-0.31.31.30.30.8
Fe content in liver0.30.31.1-0.80.71.1-0.00.2-0.6-0.20.40.3
K content in liver0.10.10.20.10.10.20.0-0.30.40.0-0.4-0.0
Mg content in liver0.20.20.6-0.00.20.5-0.10.60.80.00.20.3
Mn content in liver0.40.51.2-0.60.8-0.5-0.9-0.1-0.1-0.8-1.1-0.7
Na content in liver0.40.41.00.9-0.60.11.0-0.50.90.7-0.20.4
Rb content in liver0.30.31.6-0.0-0.11.30.40.60.30.40.40.7
Se content in liver0.70.82.3-1.21.21.5-0.51.2-0.4-0.50.20.3
Sr content in liver0.70.61.31.1-0.9-0.11.10.00.81.00.40.6
Zn content in liver0.50.51.6-0.20.21.30.31.20.40.40.80.9
Bone: minimum diameter2.03.79.03.0-2.7-2.12.0-1.41.31.81.30.4
Time in familiar zone, hab. session 10.10.10.4-0.40.1-0.2-0.60.3-0.3-0.6-0.2-0.3
Time in novel zone, hab. session 10.20.20.6-0.30.3-0.4-0.1-0.8-0.6-0.2-0.2-0.4
Total zone transitions, hab. session 12.43.34.8-2.01.8-1.3-2.1-0.9-1.5-2.2-2.0-2.1
Total locomotion distance, hab. session 10.60.81.9-1.41.20.0-1.30.4-0.5-1.1-0.4-0.7
Locomotion velocity, hab. session 10.40.61.3-1.21.0-0.0-1.20.3-0.5-0.9-0.3-0.6
Time in familiar zone, hab. session 20.60.71.91.2-1.4-0.40.80.40.80.60.50.4
Time in novel zone, hab. session 20.80.82.1-1.51.30.4-0.9-0.4-1.1-0.7-0.6-0.5
Total zone transitions, hab. session 20.30.41.0-1.01.00.1-0.70.50.1-0.7-0.5-0.4
Total locomotion distance, hab. session 20.30.41.2-1.11.00.6-0.70.8-0.0-0.50.20.0
Locomotion velocity, hab. session 20.20.30.8-0.80.80.6-0.40.90.3-0.20.30.2
Novel to familiar place preference ratio1.11.23.20.0-0.2-1.8-0.3-1.7-1.0-0.6-1.2-1.3
Novelty place preference1.01.12.5-0.2-0.0-1.6-0.4-1.5-1.2-0.7-1.1-1.2
Time in novel zone, NPP test1.11.22.4-0.40.1-1.5-0.6-1.5-1.4-0.9-1.2-1.3
Total zone transitions, NPP test1.92.78.1-2.32.90.7-1.91.0-0.6-1.8-1.3-0.8
Total locomotion distance, NPP test1.92.67.4-2.32.71.4-1.61.7-0.6-1.4-0.5-0.2
Locomotion velocity, NPP test1.31.95.5-1.92.31.3-1.31.7-0.2-1.1-0.30.0
Intraocular pressure1.01.46.3-1.40.62.5-0.41.7-0.10.10.31.0
Delta distance traveled before/after self-admin4.75.07.81.9-1.91.82.22.02.82.32.52.6
Delta ambulatory time before/after self-admin3.74.67.51.6-1.81.82.11.92.72.22.42.5
Parametrial fat weight0.71.77.5-0.40.41.7-0.22.71.20.21.11.2
Pavlov. Cond. lever latency0.60.72.0-0.2-0.31.20.51.10.30.71.41.0
Pavlov. Cond. magazine entry latency0.70.93.00.5-0.4-1.6-0.0-1.7-0.5-0.3-0.9-1.0
Pavlov. Cond. change in total contacts1.41.53.80.3-0.2-1.9-0.5-1.9-0.4-0.7-1.6-1.4
Pavlov. Cond. index score1.41.84.90.4-0.1-2.0-0.3-2.2-0.5-0.8-1.8-1.5
Pavlov. Cond. latency score1.21.64.40.4-0.1-1.9-0.3-2.1-0.4-0.7-1.8-1.4
Pavlov. Cond. lever contacts0.60.72.00.30.2-1.1-0.3-1.2-0.1-0.5-1.4-0.9
Pavlov. Cond. magazine entry number0.50.62.3-0.50.41.3-0.11.50.30.20.80.8
Pavlov. Cond. intertrial magazine entries1.51.84.8-1.71.62.0-1.02.2-0.4-0.60.10.5
Pavlov. Cond. lever-magazine prob. diff.1.41.74.40.4-0.1-2.1-0.4-2.1-0.5-0.8-1.7-1.5
Pavlov. Cond. response bias0.30.41.10.3-0.1-1.0-0.1-1.0-0.2-0.3-0.8-0.7
Pavlov. Cond. lever latency0.60.82.40.3-0.5-1.5-0.1-1.60.2-0.1-1.2-1.0
Pavlov. Cond. magazine entry latency0.60.72.2-0.20.21.20.01.5-0.30.21.31.0
Pavlov. Cond. change in total contacts0.40.61.4-0.00.0-1.2-0.5-1.0-1.0-0.8-0.6-0.9
Pavlov. Cond. index score0.40.51.5-0.30.31.10.01.2-0.4-0.01.10.8
Pavlov. Cond. latency score0.40.51.3-0.40.41.1-0.01.1-0.6-0.11.00.7
Pavlov. Cond. lever contacts0.60.92.6-0.20.31.50.21.6-0.10.21.31.1
Pavlov. Cond. magazine entry number0.20.30.9-0.1-0.0-0.7-0.1-0.90.2-0.2-0.9-0.7
Pavlov. Cond. intertrial magazine entries1.31.94.10.8-0.82.01.41.31.51.61.01.7
Pavlov. Cond. lever-magazine prob. diff.0.30.41.0-0.30.30.9-0.01.0-0.5-0.10.90.6
Pavlov. Cond. response bias0.70.92.8-0.00.11.40.21.7-0.10.31.51.1
Time in closed arm before self-admin1.21.54.2-0.20.1-1.9-0.7-2.0-1.0-0.8-1.2-1.5
Time in closed arm after self-admin1.21.32.4-0.70.4-1.4-1.0-1.4-0.8-1.0-1.6-1.4
Time in open arm before self-admin1.41.52.9-1.41.4-0.5-1.7-0.5-1.5-1.4-0.8-1.3
Time in open arm after self-admin0.10.10.3-0.30.30.6-0.20.4-0.1-0.10.30.2
Bone: periosteal estimation3.77.718.84.3-3.9-2.13.2-1.42.52.81.71.1
Bone: periosteal perimeter2.64.411.93.5-2.7-2.32.1-2.01.71.80.80.3
Bone: post-yield work2.13.06.52.5-2.4-1.32.0-0.41.61.91.40.9
Progressive ratio test 1 active lever presses1.82.27.5-1.71.12.7-0.42.2-0.3-0.01.41.1
Progressive ratio test 1 breakpoint1.82.37.8-1.51.02.8-0.32.3-0.20.11.51.3
Progressive ratio test 1 inactive lever presses0.20.20.5-0.70.70.5-0.70.4-0.3-0.30.0-0.0
Progressive ratio test 2 active lever presses0.30.41.5-0.50.31.2-0.00.70.30.30.80.6
Progressive ratio test 2 breakpoint0.20.31.0-0.50.41.0-0.20.50.10.10.60.4
Progressive ratio test 2 inactive lever presses0.71.22.60.3-0.31.40.51.11.31.01.61.3
Incentive Sensitization - Responses0.20.30.80.8-0.2-0.90.1-0.90.80.2-0.2-0.3
Incentive Sensitization - Breakpoint0.30.30.90.7-0.1-0.90.1-0.90.70.1-0.3-0.4
Sum of active levers in priming session hrs 5-60.30.20.7-0.30.8-0.2-0.9-0.0-0.0-0.6-0.2-0.5
Progressive ratio0.50.72.0-1.41.40.9-0.90.6-0.4-0.8-0.3-0.2
Food seeking constrained by brief footshock0.70.92.1-1.41.31.5-0.61.1-0.5-0.60.00.2
Seeking ratio, punishment vs. effort0.00.00.20.3-0.4-0.10.3-0.1-0.10.20.00.1
Retroperitoneal fat weight1.25.013.20.3-0.63.31.13.62.31.32.22.7
Reaction time number correct1.93.76.32.4-2.50.32.50.22.12.51.41.6
Reaction time mean minus median0.30.82.8-1.41.31.7-0.70.30.1-0.4-0.50.2
Reaction time mean minus median AUC0.30.82.3-1.51.11.1-0.90.2-0.0-0.7-0.9-0.2
Reaction time num false alarms0.71.02.8-1.71.10.5-1.4-0.2-1.0-1.1-0.7-0.6
Reaction time num false alarms AUC1.21.94.3-2.11.50.3-1.8-0.4-1.6-1.5-1.0-1.0
Reaction time trials correct on left1.93.76.32.4-2.50.32.50.22.12.51.41.6
Reaction time trials on left1.93.66.02.3-2.40.42.40.22.12.41.41.6
Reaction time mean0.10.20.8-0.1-0.30.90.20.00.40.30.70.5
Reaction time mean AUC0.10.20.60.1-0.40.70.3-0.10.50.40.60.5
Median of all reaction times0.30.41.30.5-0.90.50.6-0.10.50.61.10.6
Reaction time omissions1.32.05.1-2.32.02.1-1.11.1-0.6-0.8-0.60.1
Reaction time false alarm rate3.44.78.2-2.92.4-0.3-2.8-0.8-2.5-2.6-1.7-1.8
Reaction time premature initiation rate0.71.03.5-1.01.21.9-0.11.60.1-0.1-0.20.7
Reaction time premature initiations0.91.63.80.3-0.31.91.31.61.31.30.71.6
Std. dev. reaction times0.61.02.8-1.71.41.5-1.00.2-0.3-0.8-0.6-0.1
Reaction time trials completed1.93.66.02.3-2.40.42.40.22.12.41.41.6
Reaction time trials AUC1.93.76.82.5-2.60.12.4-0.12.02.41.41.5
Run reversals in cocaine runway, females1.01.02.81.0-1.20.21.0-0.01.71.10.70.8
Run reversals in cocaine runway, males1.11.11.6-1.00.9-0.6-1.2-1.3-1.3-1.0-1.0-1.2
Latency to leave start box in cocaine runway0.91.12.1-1.10.8-0.8-1.2-0.6-1.5-1.2-0.7-1.1
Latency to leave start box in cocaine runway, F1.72.03.4-1.81.8-0.2-1.8-0.2-1.6-1.6-1.0-1.2
Latency to leave start box in cocaine runway, M0.50.51.40.6-1.1-1.20.6-1.0-0.30.00.1-0.4
Std. dev. time between licks in bursts0.50.71.7-1.11.31.0-0.61.1-0.4-0.6-0.10.2
Total sessions with >9 infusions0.70.81.6-1.30.81.3-0.81.0-0.9-0.30.90.3
Short access day 1 total inactive lever presses0.40.51.5-0.80.81.2-0.40.9-0.6-0.10.60.4
Short access day 10 total inactive lever presses0.00.10.30.4-0.2-0.30.1-0.6-0.40.20.2-0.0
Short access day 1 total infusions1.01.33.60.0-0.51.70.71.30.40.91.91.3
Short access day 10 total infusions0.40.51.4-1.00.31.2-0.20.4-0.50.01.00.4
Short access total infusions1.31.65.3-0.6-0.02.30.41.60.30.71.81.4
Short access day 1 locomotion0.10.20.5-0.30.30.7-0.10.5-0.4-0.00.60.3
Short access day 10 total locomotion0.20.30.80.10.00.90.10.30.10.60.90.7
Short access total locomotion0.50.61.7-0.40.41.3-0.11.0-0.50.31.20.8
One hour access (0.3 mA shock)0.60.61.71.0-1.3-0.20.9-0.40.90.70.80.3
Compulsive drug intake0.30.40.90.2-0.3-0.9-0.6-0.8-0.2-0.5-0.9-0.7
One hour access (shock baseline)0.50.81.51.0-1.10.01.2-0.20.91.01.20.6
Social response proportion1.11.21.80.8-1.11.11.10.61.31.21.11.4
Social responses1.01.33.2-1.81.61.0-1.20.2-1.1-1.1-0.5-0.4
Social time1.31.72.81.5-1.50.51.60.21.21.51.71.3
Soleus weight0.30.92.81.7-1.3-0.71.1-0.51.10.90.20.5
Bone: stiffness3.96.415.33.9-3.6-3.52.3-2.21.71.90.90.1
Tibialis anterior weight4.214.132.5-0.3-0.0-5.6-2.0-5.7-3.2-3.0-4.3-4.6
Time to tail flick, vehicle, before self-admin0.30.31.0-1.00.70.6-0.60.4-0.5-0.4-0.4-0.1
Time to tail flick, vehicle, after self-admin0.20.30.70.1-0.1-0.8-0.2-0.8-0.8-0.20.3-0.7
Time to tail flick, test, before self-admin0.60.61.5-1.00.6-0.2-0.8-0.5-0.5-0.9-1.2-0.8
Time to tail flick, test, after self-admin0.30.30.70.6-0.9-0.70.6-0.70.30.40.3-0.1
Delta time to tail flick, vehicle, before/after SA0.60.51.31.1-0.9-0.30.8-0.20.30.71.10.3
Delta time to tail flick, test, before/after SA0.40.41.30.8-0.8-0.30.7-0.20.20.71.10.3
Tibia length3.08.418.54.3-3.8-0.73.5-0.02.73.12.82.1
Ambulatory time before self-admin0.60.92.2-1.21.51.4-0.61.2-0.4-0.6-0.50.2
Ambulatory time after self-admin2.12.45.80.2-0.22.41.12.21.71.21.32.0
Bone: tissue strength0.20.21.00.5-0.8-1.00.1-0.50.20.1-0.2-0.3
Total heroin consumption0.60.81.71.3-1.00.20.80.61.10.80.80.8
Bone: trabecular number2.13.58.02.8-2.0-0.62.2-0.02.42.21.01.3
Bone: trabecular spacing0.81.12.1-1.50.8-0.0-1.3-0.3-1.4-1.3-0.6-1.0
Bone: trabecular thickness0.40.51.30.10.4-1.1-0.3-0.90.3-0.4-1.2-0.8
Bone: trabecular tissue density2.94.36.0-1.71.5-2.4-2.3-1.9-2.4-2.3-1.5-2.4
Water consumed over 24 hours1.62.13.61.5-1.41.11.61.11.91.70.91.6
Number of responses in last shaping day0.20.20.6-0.50.3-0.4-0.2-0.2-0.8-0.4-0.2-0.5