Hub : Genes

Tfcp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Tfcp2 0.19 0.11 7.8e-08 0.04 0.06 0.06 0.05 5.3e-05 9.6e-07 2.9e-07 2.5e-06
2 Adipose isoform ratio XM_039079341.1 0.05 0.06 3.9e-03 0.01 0 0 0 2.3e-02 1.4e-01 9.3e-02 1.7e-01
3 Adipose alternative polyA XM_039079341.1 0.03 0.02 2.1e-03 0.01 0 0 0.01 7.1e-02 8.5e-02 1.5e-01 7.1e-02
4 Adipose alternative polyA XM_017594896.2 0.03 0.02 2.2e-03 0 0 0.01 0 7.7e-02 8.5e-02 6.0e-02 7.9e-02
5 Brain mRNA stability Tfcp2 0.1 0.05 1.1e-09 0.08 0.1 0.1 0.1 3.2e-08 5.3e-10 1.3e-09 1.1e-09
6 IL gene expression Tfcp2 0.48 0.24 6.4e-04 0.13 0.15 0.16 0.17 4.3e-04 2.1e-04 1.2e-04 5.9e-05
7 PL gene expression Tfcp2 0.32 0.18 1.4e-12 0.1 0.11 0.11 0.1 4.3e-11 3.0e-12 2.1e-12 1.5e-11
8 NAcc gene expression Tfcp2 0.06 0.05 1.3e-03 -0 0.01 0.01 0 3.9e-01 5.3e-02 6.3e-02 2.4e-01
9 Brain gene expression Tfcp2 0.19 0.09 1.0e-09 0.07 0.09 0.11 0.11 5.5e-07 7.2e-09 4.8e-10 4.1e-10
10 OFC gene expression Tfcp2 0.47 0.17 9.8e-05 0.19 0.12 0.3 0.16 3.0e-05 1.1e-03 6.4e-08 1.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density3.55.912.73.63.3-3.3-2.2-1.42.6-2.22.00.7-1.1
Area under the delay curve0.30.30.70.70.8-0.8-0.6-0.70.3-0.10.4-0.40.1
BMI with tail2.99.420.94.24.6-4.6-4.0-3.20.8-0.90.1-2.2-1.6
BMI without tail0.71.54.42.11.3-1.3-1.1-0.31.5-1.40.50.0-1.3
Body weight2.510.623.14.64.8-4.8-3.6-2.82.1-2.11.6-1.3-2.4
Weight adjusted by age0.91.01.70.50.6-0.6-1.1-1.3-1.31.2-1.2-1.30.7
Bone surface5.19.018.54.14.3-4.3-2.8-1.72.9-2.82.40.3-1.8
Bone volume4.47.417.34.23.8-3.8-2.7-1.82.7-2.42.00.4-0.9
Breakpoint value in progressive ratio session0.30.31.10.10.3-0.30.30.50.8-1.10.70.7-0.6
Number of licking bursts1.21.42.9-1.4-1.71.70.80.1-1.31.2-0.8-1.10.6
Context. condit. distance diff. score0.80.94.40.80.9-0.9-0.20.21.0-0.81.0-0.2-2.1
Locomotion velocity, session 12.22.37.6-2.8-1.81.81.81.6-1.10.9-0.70.90.5
Locomotion distance, session 11.92.44.7-2.2-1.81.81.30.9-1.41.4-1.20.82.0
Locomotion velocity, session 20.30.41.5-1.2-0.60.60.90.8-0.10.00.20.1-0.2
Locomotion distance, session 22.43.46.2-2.5-2.42.41.81.1-1.51.3-1.10.82.4
Locomotion velocity, session 33.03.47.9-2.8-2.52.52.62.3-0.10.00.21.40.1
Locomotion distance, session 32.52.75.5-1.5-1.71.72.02.31.4-1.30.92.2-0.7
Stereotopy head waving bouts, day 31.51.84.2-0.2-0.50.5-0.6-1.2-2.01.7-1.5-1.61.9
Stereotopy head waving duration, day 30.50.51.1-0.7-1.01.00.5-0.0-1.00.7-0.3-0.51.0
Locomotion velocity, session 72.02.24.2-1.4-1.91.91.92.10.9-0.90.51.6-0.2
Locomotion distance, session 72.93.77.4-2.4-2.32.42.72.70.6-0.60.81.8-0.8
Stereotopy head waving bouts, day 71.82.03.81.10.8-0.8-1.8-1.9-1.41.0-1.5-1.91.1
Stereotopy head waving duration, day 71.72.14.41.21.1-1.1-1.9-2.1-1.30.9-1.3-2.10.8
Locomotion velocity, session 80.20.20.6-0.8-0.60.60.40.4-0.40.4-0.50.1-0.2
Locomotion distance, session 80.60.82.3-1.5-1.01.01.31.3-0.10.20.10.7-0.4
Degree of sensitization distance0.30.31.1-0.20.1-0.1-0.2-0.4-1.10.9-0.5-0.90.1
Degree of sensitization stereotypy2.02.24.41.31.3-1.3-2.1-2.0-1.10.9-1.6-1.90.6
Conditioned locomotion0.20.20.3-0.0-0.50.50.50.50.4-0.50.50.1-0.2
Cocaine response after cond. corrected0.30.41.2-0.2-0.30.3-0.2-0.4-0.90.6-0.5-0.71.1
Cocaine response after cond. not corrected0.20.21.2-0.4-0.50.50.20.1-0.50.2-0.40.21.1
Cocaine response before conditioning1.31.64.5-1.3-1.11.11.61.80.7-0.60.62.1-0.6
Saline control response0.60.82.00.60.1-0.10.20.71.4-1.40.91.3-0.8
Bone: connectivity density2.23.46.52.12.5-2.5-1.4-0.62.0-1.91.80.7-1.7
Bone: cortical apparent density1.31.86.1-0.2-0.80.8-0.3-0.6-1.91.9-1.6-0.22.5
Bone: cortical area3.04.59.63.12.9-2.9-2.0-1.32.2-2.11.60.4-0.8
Bone: cortical porosity0.91.02.40.60.3-0.30.40.81.6-1.51.41.1-1.0
Bone: cortical porosity0.90.92.10.4-0.00.10.61.01.4-1.41.31.2-0.8
Bone: cortical thickness0.81.42.81.71.6-1.6-1.0-0.71.3-1.10.90.6-0.2
Bone: cortical thickness0.50.62.7-0.3-0.30.30.60.80.9-0.90.41.70.0
Bone: cortical tissue density1.31.85.9-0.3-1.01.0-0.1-0.5-1.91.9-1.6-0.22.4
Condit. Reinf. active minus inactive responses0.10.10.2-0.10.3-0.3-0.3-0.1-0.2-0.0-0.30.4-0.1
Condit. Reinf. active-inactive response ratio0.50.61.40.40.6-0.6-0.20.20.8-1.20.81.0-1.0
Condit. Reinf. active responses0.30.41.1-0.8-0.30.30.10.1-1.00.8-1.00.10.4
Condit. Reinf. inactive responses2.32.75.2-1.9-1.71.71.00.4-2.12.3-1.8-0.51.9
Incentive salience index mean0.30.30.60.20.8-0.8-0.8-0.6-0.40.3-0.7-0.10.2
Condit. Reinf. lever presses0.91.22.30.61.3-1.3-1.5-1.5-0.90.8-1.0-1.30.5
Condit. Reinf. active minus inactive responses0.81.02.21.11.5-1.5-1.3-1.1-0.00.3-0.2-0.70.4
Condit. Reinf. active-inactive response ratio0.50.51.40.81.2-1.2-0.9-0.80.3-0.10.1-0.30.1
Condit. Reinf. active responses0.30.40.80.70.8-0.8-0.9-0.7-0.20.3-0.5-0.20.7
Condit. Reinf. inactive responses0.20.30.9-0.3-0.50.50.10.2-0.60.6-0.90.40.7
Condit. Reinf. lever presses0.40.51.1-0.2-0.30.30.80.91.0-0.61.01.0-0.0
Condit. Reinf. lever reinforcers received0.10.10.30.20.4-0.4-0.3-0.2-0.00.2-0.30.20.6
Conditioned reinforcement - actives1.11.12.8-1.3-1.41.40.80.4-0.90.7-0.70.41.7
Conditioned reinforcement - inactives1.21.42.8-1.5-1.51.51.10.9-0.10.2-0.31.41.7
Conditioned locomotion0.40.41.1-1.1-0.70.71.00.8-0.0-0.20.50.2-0.2
Patch foraging indifference point 0 sec1.83.05.8-2.0-2.42.42.02.2-0.10.1-0.72.20.4
Patch foraging indifference point AUC0.70.81.9-0.6-0.30.3-0.2-0.5-1.31.2-1.2-0.81.4
Delay disc. indifference point, 0s delay0.60.71.51.01.2-1.2-0.9-0.80.6-0.50.6-0.40.1
Delay disc. indifference point, 16s delay0.30.30.70.70.8-0.8-0.5-0.50.6-0.50.5-0.2-0.4
Delay disc. indifference point, 2s delay2.93.26.52.01.5-1.5-2.4-2.6-1.21.4-1.5-2.01.3
Delay disc. indifference point, 24s delay0.30.31.00.30.6-0.6-0.4-0.60.00.00.1-1.0-0.3
Delay disc. indifference point, 4s delay0.30.30.70.70.8-0.8-0.7-0.80.3-0.10.3-0.20.4
Delay disc. indifference point, 8s delay0.70.71.50.91.0-1.0-0.3-0.21.1-0.91.20.2-1.0
Indifference point function ln k2.33.26.32.52.5-2.5-1.6-1.11.5-1.71.5-0.1-1.5
Indifference point function log k2.33.26.32.52.5-2.5-1.6-1.11.5-1.71.5-0.1-1.5
Patch foraging total patch changes 0 sec2.03.25.9-2.0-2.42.42.12.40.2-0.2-0.32.40.1
Patch foraging total patch changes 12 sec1.92.44.8-2.2-2.12.11.61.6-1.01.2-1.21.10.8
Patch foraging total patch changes 18 sec2.83.67.3-2.7-2.62.62.11.9-0.71.0-1.01.51.2
Patch foraging total patch changes 24 sec1.51.93.7-1.9-1.91.91.51.5-0.30.5-0.61.20.8
Patch foraging total patch changes 6 sec2.53.77.3-2.7-2.72.72.01.9-0.91.1-1.21.71.3
Patch foraging time to switch 0 sec0.81.22.5-1.0-1.61.60.70.6-0.91.2-1.40.10.8
Patch foraging water rate 0 sec1.52.44.61.72.1-2.1-1.1-0.81.4-1.51.6-0.2-1.7
Patch foraging water rate 12 sec1.11.72.91.31.7-1.7-0.7-0.41.5-1.51.70.4-1.0
Patch foraging water rate 18 sec0.10.10.40.50.4-0.4-0.1-0.20.3-0.00.60.2-0.2
Patch foraging water rate 24 sec1.52.14.52.12.1-2.1-1.5-1.21.0-0.81.1-0.3-0.9
Patch foraging water rate 6 sec2.43.57.32.12.7-2.7-1.5-1.11.8-1.71.9-0.2-1.8
Seeking ratio, delayed vs. immediate footshock0.50.51.40.91.2-1.2-0.9-0.80.1-0.10.0-0.5-0.1
Distance traveled before self-admin0.91.02.0-1.4-1.41.41.11.0-0.70.7-0.70.00.5
Distance traveled after self-admin0.70.81.9-1.1-0.70.71.31.40.3-0.40.70.5-1.0
Extensor digitorum longus weight4.417.237.45.55.0-5.0-6.1-5.6-1.21.1-2.2-3.81.0
Bone: elastic displacement4.85.511.0-3.3-3.13.13.33.0-0.60.40.31.9-0.3
Bone: elastic work1.01.32.6-1.2-0.70.71.61.50.7-0.71.51.6-0.4
Bone: endosteal estimation3.78.015.53.93.7-3.7-2.4-1.53.0-3.22.6-0.0-1.9
Bone: endosteal perimeter3.16.515.03.93.4-3.4-2.6-2.02.4-2.31.9-0.4-0.9
Epididymis fat weight1.84.110.4-0.50.3-0.31.52.02.6-2.62.61.8-3.2
Delta time in closed arm before/after self-admin0.10.10.30.30.4-0.4-0.00.10.6-0.50.5-0.2-0.5
Delta time in open arm before/after self-admin2.92.85.7-2.0-1.81.82.32.40.6-0.60.92.1-0.7
Diff in mean of infusions in LGA sessions1.51.73.41.81.8-1.8-1.7-1.40.3-0.2-0.3-1.3-0.6
Delay discount exponential model param0.30.30.7-0.7-0.80.80.70.8-0.2-0.0-0.30.4-0.2
Extinction: sum of active levers before priming1.21.22.51.41.6-1.6-1.4-1.1-0.00.1-0.4-0.8-0.8
Active lever presses in extinction session 60.10.10.6-0.00.1-0.10.20.20.3-0.60.40.80.2
Bone: final force5.48.716.73.74.1-4.1-2.3-1.43.1-3.12.90.8-2.0
Bone: final moment6.210.118.14.14.3-4.3-2.3-1.33.5-3.43.30.9-2.3
Food consumed during 24 hour testing period1.92.35.81.01.8-1.8-0.30.21.6-1.81.90.2-2.4
Glucose0.00.00.2-0.20.0-0.0-0.00.2-0.00.0-0.50.20.2
Heart weight0.30.41.20.70.6-0.6-0.20.31.1-1.00.70.7-0.4
Delay discount hyperbolic model param0.50.51.1-0.9-0.90.90.91.00.0-0.2-0.00.6-0.3
Intermittent access intake day 1-15 change1.01.02.3-0.6-0.50.51.11.21.1-0.91.11.5-0.7
Intermittent access intake escalation1.31.33.1-0.5-0.20.21.11.31.5-1.31.51.7-0.9
Intermittent access intake escalation 20.90.92.8-0.4-0.20.20.81.11.3-1.11.01.7-0.6
Intermitt. access day 1 inactive lever presses0.40.41.1-0.7-0.60.60.60.70.4-0.30.31.10.5
Intermitt. access day 15 inactive lever presses0.50.51.0-0.7-0.90.91.00.90.5-0.30.80.80.2
Intermitt. access escalation Index1.41.32.9-0.7-0.70.7-0.2-0.6-1.71.6-1.7-1.31.0
Intermittent access day 1 total infusions0.80.92.2-1.1-1.51.51.10.9-0.3-0.2-0.10.91.0
Intermittent access day 15 total infusions1.51.72.9-1.5-1.71.71.71.70.4-0.50.61.60.2
Intermittent access terminal intake (last 3 days)1.21.32.7-1.2-1.61.61.41.30.1-0.30.21.30.5
Intermittent access total infusions1.21.32.6-1.3-1.61.61.41.30.1-0.40.31.50.6
Intermittent access day 1 locomotion1.41.52.7-1.5-1.61.61.71.50.3-0.40.61.20.1
Intermittent access day 15 total locomotion1.92.13.6-1.5-1.41.41.91.91.2-1.11.31.7-0.5
Intermittent access total locomotion2.73.15.9-2.4-2.42.42.32.20.2-0.20.51.70.5
Intermittent access standard deviation1.31.43.5-0.3-0.30.31.01.31.5-1.51.61.9-0.8
Left kidney weight0.92.44.92.02.2-2.2-1.4-0.71.6-1.41.00.3-1.4
Right kidney weight1.44.09.92.53.1-3.1-2.4-1.81.2-1.00.5-0.7-1.3
Cocaine induced anxiety1.11.22.51.01.2-1.2-0.30.21.6-1.41.30.8-1.3
Post-drug Anxiety2.93.25.92.42.4-2.4-1.5-1.01.9-1.81.4-0.2-1.6
Baseline Anxiety0.30.31.00.50.6-0.6-0.5-0.7-0.0-0.10.2-1.0-0.2
Tail length0.51.54.10.8-0.60.60.81.12.0-1.71.51.4-0.8
Length with tail0.72.75.32.31.9-1.9-1.1-0.72.1-1.71.90.4-1.2
Length without tail1.63.59.12.33.0-3.0-2.2-2.01.0-0.81.0-0.6-0.7
Times rat made contact with spout0.30.31.2-0.00.4-0.40.10.40.8-0.70.50.4-1.1
Lifetime Intake1.92.23.9-1.7-2.02.01.91.80.2-0.60.61.80.4
Liver weight, left1.21.83.71.41.4-1.4-0.5-0.21.9-1.91.70.9-1.1
Liver weight, right1.42.34.21.41.8-1.8-0.50.12.0-2.01.81.1-1.5
Locomotor activity0.50.71.9-1.4-1.11.10.90.8-0.20.5-0.50.50.9
Locomotor testing distance1.11.94.0-2.0-1.91.91.71.6-0.20.5-0.51.30.9
Locomotor testing rearing0.60.92.7-0.8-1.01.01.11.50.7-0.5-0.11.60.0
Locomotion in novel chamber1.62.05.62.41.7-1.7-1.8-1.70.5-0.50.1-1.1-0.7
Locomotion in novel chamber post-restriction0.60.71.80.40.5-0.50.20.41.1-1.21.30.5-1.2
Fecal boli incidents, locomotor time 11.51.63.2-1.6-0.90.91.81.80.7-0.91.11.1-1.3
Change in fecal boli incidents, locomotor task0.80.72.40.40.2-0.2-0.9-1.1-0.90.9-0.9-0.51.5
Time >=10cm from walls, locomotor time 10.30.30.6-0.6-0.70.70.80.70.3-0.20.30.1-0.4
Bouts of movement, locomotor time 10.30.31.0-0.6-0.00.0-0.1-0.4-0.60.6-0.4-0.71.0
Total resting periods, locomotor time 10.60.72.1-1.2-0.80.80.50.1-0.90.8-0.5-0.11.5
Rest time, locomotor task time 10.40.51.1-1.0-0.90.90.70.4-0.50.4-0.40.41.0
Distance moved, locomotor task time 10.10.10.30.2-0.20.2-0.2-0.2-0.40.4-0.4-0.6-0.3
Vertical activity count, locomotor time 10.90.92.71.61.1-1.1-1.3-1.00.2-0.1-0.2-0.7-0.9
Time >=10cm from walls, locomotor time 20.30.30.6-0.6-0.80.80.70.70.2-0.20.30.7-0.0
Bouts of movement, locomotor time 21.71.85.02.21.8-1.8-1.5-1.20.8-0.70.7-0.8-0.8
Total resting periods, locomotor time 22.02.15.82.42.0-2.0-1.8-1.60.6-0.40.4-1.0-0.4
Rest time, locomotor task time 20.20.21.2-0.4-0.30.3-0.0-0.2-0.50.4-0.50.11.1
Distance moved, locomotor task time 20.10.10.3-0.2-0.30.30.10.0-0.50.5-0.4-0.3-0.2
Vertical activity count, locomotor time 20.20.20.90.50.4-0.4-0.3-0.20.00.2-0.0-0.5-0.9
Light reinforcement 10.81.43.1-1.8-1.61.51.00.3-1.11.4-0.8-0.31.2
Light reinforcement 20.10.20.7-0.2-0.10.1-0.1-0.4-0.40.8-0.3-0.70.5
Bone: marrow area3.57.714.83.83.6-3.6-2.3-1.43.0-3.12.60.1-1.8
Bone: maximum diameter0.91.74.22.11.7-1.7-1.3-0.91.4-1.20.80.00.0
Bone: maximum force5.810.021.44.34.6-4.6-3.0-2.22.8-2.82.7-0.0-1.6
Bone: maximum moment6.611.422.94.74.8-4.8-3.0-2.13.2-3.13.10.1-2.0
Mean time between licks in bursts0.70.92.4-1.5-1.11.21.20.6-0.80.90.3-0.30.8
Mean num. licks in bursts1.72.14.31.11.5-1.5-0.30.72.1-1.81.31.7-1.4
Cd content in liver0.30.40.7-0.8-0.80.80.80.7-0.2-0.10.20.2-0.4
Co content in liver0.10.20.9-0.10.2-0.2-0.00.30.3-0.4-0.30.4-0.9
Cu content in liver0.60.71.71.10.9-0.9-0.6-0.11.3-1.10.40.6-0.7
Fe content in liver0.70.82.3-1.1-1.51.51.00.7-0.20.2-0.30.60.7
K content in liver0.10.10.3-0.50.2-0.20.10.20.00.2-0.20.5-0.1
Mg content in liver0.20.21.0-1.0-0.10.10.40.2-0.40.6-0.30.10.1
Mn content in liver0.30.30.70.30.9-0.9-0.8-0.7-0.20.3-0.4-0.40.1
Na content in liver0.10.10.5-0.10.1-0.1-0.10.10.50.1-0.50.70.6
Rb content in liver0.91.13.4-1.2-1.21.21.31.40.0-0.1-0.21.80.2
Se content in liver0.80.92.9-1.7-1.21.20.90.7-0.90.6-0.8-0.2-0.3
Sr content in liver0.90.81.9-0.1-0.00.00.60.91.3-1.41.11.2-0.6
Zn content in liver1.41.54.3-2.1-1.61.61.71.5-0.40.4-0.00.6-0.3
Bone: minimum diameter3.36.213.83.73.3-3.3-2.4-1.92.2-2.42.1-0.6-1.1
Time in familiar zone, hab. session 10.30.31.0-0.40.3-0.3-0.1-0.2-0.60.5-0.3-1.0-0.6
Time in novel zone, hab. session 10.20.20.90.4-0.30.3-0.2-0.4-0.20.3-0.20.11.0
Total zone transitions, hab. session 11.82.65.7-0.4-0.20.1-0.9-1.4-2.22.4-2.1-1.62.3
Total locomotion distance, hab. session 10.70.92.5-1.2-0.70.70.4-0.0-1.31.3-0.9-0.11.6
Locomotion velocity, hab. session 10.50.72.6-1.0-0.50.50.3-0.1-1.11.1-0.8-0.01.6
Time in familiar zone, hab. session 21.41.44.81.01.6-1.6-0.8-0.40.6-0.90.8-0.8-2.2
Time in novel zone, hab. session 21.61.65.8-0.9-1.61.60.70.3-0.71.1-1.00.82.4
Total zone transitions, hab. session 20.40.62.1-1.0-0.80.80.50.1-0.60.7-0.50.21.5
Total locomotion distance, hab. session 20.60.81.6-1.2-1.11.11.00.5-0.60.5-0.20.81.3
Locomotion velocity, hab. session 20.50.71.4-1.0-1.01.00.90.6-0.20.30.10.91.2
Novel to familiar place preference ratio1.41.53.41.51.3-1.3-1.8-1.8-0.40.4-0.8-0.90.9
Novelty place preference1.11.22.71.21.0-1.0-1.5-1.6-0.60.5-0.9-0.91.0
Time in novel zone, NPP test1.11.22.61.10.9-0.9-1.5-1.6-0.80.7-1.0-1.01.1
Total zone transitions, NPP test2.13.05.8-2.4-2.12.11.30.7-1.62.0-1.40.32.3
Total locomotion distance, NPP test2.93.99.1-3.0-2.62.62.21.4-1.41.7-0.80.91.8
Locomotion velocity, NPP test2.12.97.4-2.7-2.22.22.01.3-1.11.3-0.50.91.4
Intraocular pressure2.13.05.4-2.2-2.22.22.32.3-0.50.4-0.12.10.2
Delta distance traveled before/after self-admin1.82.04.00.10.6-0.50.81.21.8-1.82.01.6-2.0
Delta ambulatory time before/after self-admin1.82.04.0-0.10.3-0.30.91.31.9-1.82.01.9-1.6
Parametrial fat weight1.32.55.4-2.1-1.31.42.32.30.6-0.71.21.3-1.4
Pavlov. Cond. lever latency0.81.01.9-0.8-1.11.11.41.30.5-0.71.10.8-0.7
Pavlov. Cond. magazine entry latency1.21.53.21.61.4-1.4-1.8-1.8-0.40.5-0.7-1.10.7
Pavlov. Cond. change in total contacts2.02.14.41.61.8-1.8-2.1-2.0-0.50.5-1.0-1.40.4
Pavlov. Cond. index score1.72.14.71.71.7-1.7-2.2-2.0-0.50.6-1.2-1.00.9
Pavlov. Cond. latency score1.52.04.31.61.7-1.7-2.1-1.9-0.40.6-1.2-0.80.9
Pavlov. Cond. lever contacts0.50.61.40.81.0-1.0-1.2-1.0-0.10.3-0.8-0.20.5
Pavlov. Cond. magazine entry number0.60.71.5-1.2-1.11.11.21.0-0.1-0.00.30.70.2
Pavlov. Cond. intertrial magazine entries2.53.07.1-2.7-2.22.22.22.0-0.90.9-0.61.40.8
Pavlov. Cond. lever-magazine prob. diff.1.72.14.71.71.8-1.8-2.2-2.0-0.40.5-1.1-1.00.8
Pavlov. Cond. response bias0.40.51.10.90.9-0.9-1.1-1.0-0.00.2-0.4-0.60.3
Pavlov. Cond. lever latency1.01.33.11.51.5-1.5-1.8-1.4-0.1-0.2-0.4-0.6-0.5
Pavlov. Cond. magazine entry latency0.91.02.6-1.4-1.21.21.61.20.3-0.21.10.2-0.5
Pavlov. Cond. change in total contacts0.71.02.40.80.8-0.8-1.1-1.3-0.70.9-0.8-1.50.9
Pavlov. Cond. index score0.81.02.5-1.4-1.41.41.61.1-0.00.20.50.20.3
Pavlov. Cond. latency score0.70.92.1-1.3-1.31.31.51.00.00.20.50.10.3
Pavlov. Cond. lever contacts1.11.53.8-1.5-1.61.61.91.50.30.10.70.80.3
Pavlov. Cond. magazine entry number0.20.30.80.80.6-0.6-0.9-0.6-0.20.0-0.60.00.1
Pavlov. Cond. intertrial magazine entries1.51.94.4-0.4-0.50.51.11.91.5-1.70.72.1-1.8
Pavlov. Cond. lever-magazine prob. diff.0.40.51.3-1.0-1.01.01.10.7-0.10.20.4-0.10.4
Pavlov. Cond. response bias1.01.43.7-1.6-1.41.41.91.50.3-0.11.00.5-0.2
Time in closed arm before self-admin0.80.91.91.21.0-1.0-1.4-1.4-0.40.5-0.6-0.90.1
Time in closed arm after self-admin0.80.91.60.80.7-0.7-1.2-1.3-0.60.9-0.9-1.20.6
Time in open arm before self-admin1.51.63.30.30.2-0.2-1.1-1.5-1.51.3-1.5-1.81.7
Time in open arm after self-admin0.20.20.4-0.7-0.60.60.40.2-0.60.4-0.3-0.20.3
Bone: periosteal estimation4.79.619.84.54.1-4.1-2.7-1.83.3-3.42.70.2-1.6
Bone: periosteal perimeter4.37.117.64.23.7-3.7-3.0-2.32.2-2.01.6-0.5-0.6
Bone: post-yield work3.64.99.73.13.1-3.1-2.0-1.42.1-2.02.0-0.1-1.5
Progressive ratio test 1 active lever presses4.95.110.1-3.1-3.23.22.92.7-0.30.10.12.30.8
Progressive ratio test 1 breakpoint4.04.28.7-2.7-3.03.02.62.3-0.30.2-0.12.00.9
Progressive ratio test 1 inactive lever presses1.41.52.9-1.7-1.71.71.41.3-0.20.4-0.11.31.0
Progressive ratio test 2 active lever presses1.51.63.1-1.5-1.61.61.61.50.4-0.50.41.80.6
Progressive ratio test 2 breakpoint1.41.52.9-1.5-1.61.61.51.50.4-0.40.31.70.6
Progressive ratio test 2 inactive lever presses1.41.63.5-1.3-1.41.41.51.60.7-0.80.81.90.6
Incentive Sensitization - Responses0.40.40.70.80.7-0.7-0.7-0.50.7-0.50.10.50.7
Incentive Sensitization - Breakpoint0.40.40.70.80.7-0.7-0.8-0.60.6-0.3-0.00.50.9
Sum of active levers in priming session hrs 5-60.40.41.1-1.0-0.80.80.60.4-0.60.5-0.40.30.7
Progressive ratio0.70.81.9-1.4-1.21.21.00.7-0.70.5-0.30.30.5
Food seeking constrained by brief footshock0.81.02.1-1.4-1.51.51.31.2-0.50.4-0.30.60.4
Seeking ratio, punishment vs. effort0.10.10.20.50.5-0.5-0.2-0.10.4-0.30.3-0.1-0.4
Retroperitoneal fat weight1.03.47.2-2.7-1.71.72.72.60.5-0.51.11.5-1.9
Reaction time number correct2.02.96.41.61.6-1.6-0.60.32.4-2.51.71.9-1.4
Reaction time mean minus median1.62.14.5-1.8-2.12.11.51.5-0.50.7-1.01.11.2
Reaction time mean minus median AUC1.11.52.4-1.4-1.51.51.01.0-0.81.0-1.40.71.4
Reaction time num false alarms1.11.53.2-1.8-1.61.61.00.4-1.61.4-0.9-0.70.6
Reaction time num false alarms AUC1.52.14.2-1.9-1.61.60.90.2-2.01.8-1.3-1.01.0
Reaction time trials correct on left2.02.96.41.61.6-1.6-0.60.32.4-2.51.71.9-1.4
Reaction time trials on left1.92.76.11.41.5-1.5-0.50.42.4-2.51.62.0-1.4
Reaction time mean0.30.51.1-0.2-1.01.00.80.80.4-0.20.11.00.1
Reaction time mean AUC0.20.31.00.0-0.70.70.60.70.5-0.30.21.0-0.1
Median of all reaction times0.20.20.70.4-0.40.40.30.40.6-0.60.50.8-0.3
Reaction time omissions3.64.99.4-2.7-3.13.12.52.4-0.50.7-0.82.61.8
Reaction time false alarm rate3.04.28.9-2.1-2.01.90.7-0.3-3.02.9-2.1-2.11.7
Reaction time premature initiation rate1.92.54.8-2.2-2.02.02.12.1-0.30.1-0.11.6-0.4
Reaction time premature initiations1.62.26.8-1.2-1.01.01.72.21.0-1.30.82.6-1.1
Std. dev. reaction times1.72.34.9-1.9-2.22.21.51.3-0.81.1-1.21.01.4
Reaction time trials completed1.92.76.11.41.5-1.5-0.50.42.4-2.51.62.0-1.4
Reaction time trials AUC2.13.06.21.81.8-1.8-0.80.12.4-2.51.61.7-1.4
Run reversals in cocaine runway, females0.70.61.40.80.6-0.6-0.00.31.2-1.01.10.5-1.0
Run reversals in cocaine runway, males1.01.03.10.1-0.50.5-0.6-0.6-1.11.3-1.8-0.81.4
Latency to leave start box in cocaine runway1.11.12.5-0.4-0.40.4-0.4-1.0-1.61.5-1.2-1.31.4
Latency to leave start box in cocaine runway, F2.73.05.6-1.7-1.61.60.4-0.4-2.32.2-2.0-1.32.4
Latency to leave start box in cocaine runway, M1.11.02.21.51.5-1.4-1.2-1.10.3-0.40.5-0.4-0.9
Std. dev. time between licks in bursts1.01.23.1-1.8-1.51.51.41.0-0.50.7-0.10.20.3
Total sessions with >9 infusions1.31.42.7-1.3-1.71.71.51.3-0.0-0.20.31.40.9
Short access day 1 total inactive lever presses0.70.71.7-1.3-1.11.11.21.1-0.20.00.00.70.4
Short access day 10 total inactive lever presses0.40.41.10.40.3-0.30.10.41.0-0.90.80.5-0.8
Short access day 1 total infusions0.70.71.5-0.7-1.11.11.01.00.3-0.70.41.20.5
Short access day 10 total infusions1.92.14.6-1.8-2.12.11.81.6-0.4-0.10.01.30.9
Short access total infusions1.71.93.3-1.5-1.81.81.81.70.3-0.80.71.70.3
Short access day 1 locomotion0.20.20.4-0.6-0.50.50.40.3-0.30.3-0.10.20.6
Short access day 10 total locomotion0.20.20.4-0.4-0.60.60.40.50.4-0.30.20.60.6
Short access total locomotion0.50.51.1-0.9-1.11.10.80.70.00.00.00.50.7
One hour access (0.3 mA shock)0.10.10.30.50.1-0.1-0.2-0.10.2-0.50.2-0.0-0.2
Compulsive drug intake1.31.33.31.51.3-1.3-1.3-1.4-0.20.1-0.2-1.8-0.7
One hour access (shock baseline)0.20.20.70.30.0-0.0-0.00.20.6-0.80.40.80.2
Social response proportion0.91.02.0-0.2-0.10.10.81.11.3-1.31.11.4-1.2
Social responses1.52.04.0-2.0-2.02.01.31.0-1.21.1-1.20.61.0
Social time0.70.92.20.20.4-0.40.40.61.3-1.31.51.2-0.8
Soleus weight0.51.33.01.51.7-1.7-1.0-0.81.2-0.80.9-0.3-0.6
Bone: stiffness7.311.424.14.94.9-4.9-3.7-3.02.5-2.52.3-0.9-1.2
Tibialis anterior weight5.016.934.14.84.1-4.1-5.8-5.6-2.32.2-3.2-4.81.8
Time to tail flick, vehicle, before self-admin0.30.30.7-0.6-0.80.80.20.0-0.70.6-0.8-0.00.4
Time to tail flick, vehicle, after self-admin0.30.41.01.00.6-0.6-0.9-0.90.0-0.3-0.2-0.30.2
Time to tail flick, test, before self-admin0.60.61.70.0-0.30.3-0.3-0.5-0.91.3-1.1-0.71.1
Time to tail flick, test, after self-admin0.70.81.41.21.0-1.0-0.7-0.31.1-1.00.7-0.0-1.0
Delta time to tail flick, vehicle, before/after SA0.70.71.61.00.9-0.9-0.4-0.11.1-1.30.90.5-0.6
Delta time to tail flick, test, before/after SA0.90.81.60.80.9-0.9-0.4-0.11.0-1.31.00.4-1.2
Tibia length2.87.913.23.63.2-3.1-1.5-0.63.5-3.53.21.0-2.8
Ambulatory time before self-admin1.71.74.1-2.0-1.81.81.61.4-0.90.8-0.70.30.4
Ambulatory time after self-admin1.71.84.2-1.7-1.31.32.02.00.6-0.61.01.0-1.2
Bone: tissue strength0.90.82.21.11.5-1.5-1.1-1.0-0.10.10.2-0.6-0.3
Total heroin consumption1.21.42.60.81.3-1.3-0.10.31.5-1.51.50.2-1.6
Bone: trabecular number2.33.65.92.32.4-2.4-1.2-0.42.4-2.12.01.1-1.6
Bone: trabecular spacing0.70.91.7-0.7-1.11.10.2-0.1-1.31.2-1.2-0.51.1
Bone: trabecular thickness0.50.61.20.90.9-0.9-1.1-0.9-0.00.2-0.4-0.11.1
Bone: trabecular tissue density2.33.27.90.50.3-0.3-1.4-2.3-2.22.2-1.5-2.22.8
Water consumed over 24 hours1.61.93.9-0.2-0.20.21.11.51.8-1.81.71.7-2.0
Number of responses in last shaping day0.10.10.30.40.4-0.4-0.3-0.4-0.1-0.10.2-0.6-0.6