Hub : Genes

Gpr137

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Gpr137 0.07 0.05 7.0e-03 0.04 0.04 0.02 0.01 1.3e-02 1.1e-02 3.6e-02 7.5e-02
2 Brain mRNA stability Gpr137 0.03 0.02 9.9e-03 0.02 -0 -0 0 1.0e-02 3.8e-01 3.9e-01 2.4e-01
3 Liver gene expression Gpr137 0.06 0.03 1.7e-04 0.01 0.01 0.01 0.01 3.2e-02 8.1e-03 9.5e-03 2.7e-02
4 Brain gene expression Gpr137 0.15 0.08 2.0e-14 0.12 0.14 0.14 0.13 2.9e-11 1.2e-12 1.0e-12 2.0e-12
5 Adipose gene expression Gpr137 0.07 0.04 2.5e-07 0.05 0.04 0.03 0.04 1.2e-06 2.4e-05 4.8e-04 3.3e-05
6 pVTA gene expression Gpr137 0.13 0.06 5.7e-14 0.16 0.17 0.16 0.16 1.8e-12 1.2e-13 4.7e-13 5.9e-13
7 NAcc gene expression Gpr137 0.1 0.06 5.6e-17 0.09 0.12 0.11 0.11 2.8e-13 2.2e-17 2.1e-16 1.6e-16
8 IL gene expression Gpr137 0.4 0.16 3.7e-07 0.17 0.24 0.26 0.2 6.0e-05 1.4e-06 4.6e-07 1.7e-05
9 PL gene expression Gpr137 0.31 0.17 1.5e-05 0.04 0.05 0.06 0.06 2.1e-05 6.3e-06 9.6e-07 4.7e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.61.12.00.70.90.1-1.2-0.71.21.4-1.21.2
Area under the delay curve0.10.20.30.00.10.0-0.5-0.40.50.6-0.60.2
BMI with tail2.69.116.32.02.30.6-3.2-2.43.64.0-3.53.9
BMI without tail0.73.75.61.41.41.0-2.3-1.92.32.4-2.41.8
Body weight3.515.521.63.43.62.3-4.3-3.74.44.6-4.34.3
Weight adjusted by age0.61.82.51.61.51.3-1.4-1.41.31.3-0.81.3
Bone surface3.87.410.92.73.11.4-3.0-2.13.13.3-2.62.7
Bone volume1.22.54.21.41.70.3-1.7-0.91.82.0-1.51.9
Breakpoint value in progressive ratio session2.13.95.32.32.31.8-2.0-1.92.01.9-2.21.1
Number of licking bursts0.10.20.40.60.60.4-0.4-0.40.50.5-0.30.2
Context. condit. distance diff. score1.01.22.1-1.4-1.4-1.21.01.0-1.0-0.91.0-0.4
Locomotion velocity, session 10.10.10.2-0.00.10.1-0.4-0.40.50.4-0.3-0.2
Locomotion distance, session 10.50.71.40.30.60.1-1.0-0.71.11.2-0.90.7
Locomotion velocity, session 22.63.13.81.71.81.3-1.9-1.71.91.9-1.81.6
Locomotion distance, session 20.50.71.20.60.70.6-1.0-1.01.11.1-0.90.3
Locomotion velocity, session 30.40.51.9-1.0-0.7-1.40.00.50.10.40.10.7
Locomotion distance, session 30.10.10.3-0.2-0.2-0.3-0.10.00.10.2-0.20.6
Stereotopy head waving bouts, day 30.50.62.1-1.3-1.1-1.50.30.7-0.20.10.1-0.4
Stereotopy head waving duration, day 30.60.81.7-1.2-1.1-1.30.81.0-0.7-0.50.7-0.5
Locomotion velocity, session 70.40.51.6-1.0-0.8-1.30.40.8-0.4-0.10.30.1
Locomotion distance, session 70.10.10.2-0.4-0.4-0.3-0.2-0.10.20.30.00.3
Stereotopy head waving bouts, day 70.10.10.4-0.10.0-0.70.10.50.00.2-0.00.3
Stereotopy head waving duration, day 70.60.71.30.91.00.3-0.8-0.50.91.0-0.91.1
Locomotion velocity, session 81.21.42.11.01.11.1-1.4-1.41.41.2-1.3-0.5
Locomotion distance, session 80.20.21.1-0.8-0.6-1.00.00.40.10.20.0-0.2
Degree of sensitization distance0.10.10.2-0.3-0.3-0.5-0.2-0.00.30.40.00.2
Degree of sensitization stereotypy0.30.40.80.60.80.0-0.5-0.10.60.7-0.50.9
Conditioned locomotion1.31.52.01.31.31.1-1.4-1.31.41.4-1.10.7
Cocaine response after cond. corrected0.71.02.2-1.4-1.5-1.11.00.7-0.8-0.80.7-0.6
Cocaine response after cond. not corrected0.40.61.5-1.1-1.2-0.90.70.5-0.6-0.60.4-0.3
Cocaine response before conditioning0.60.71.31.11.10.8-0.8-0.60.70.7-0.60.8
Saline control response4.86.67.52.72.62.6-2.6-2.72.52.4-2.52.5
Bone: connectivity density2.64.16.11.92.11.1-2.3-1.72.32.5-1.92.3
Bone: cortical apparent density0.10.20.70.50.30.80.1-0.3-0.2-0.4-0.30.2
Bone: cortical area0.61.01.81.01.10.6-0.9-0.70.91.1-0.81.4
Bone: cortical porosity0.10.20.50.40.40.4-0.3-0.30.20.1-0.7-0.4
Bone: cortical porosity0.50.61.10.80.80.8-0.8-0.80.70.6-1.1-0.1
Bone: cortical thickness2.94.88.12.52.32.8-2.0-2.41.91.6-2.01.9
Bone: cortical thickness0.70.81.60.80.81.3-1.0-1.30.90.7-0.90.3
Bone: cortical tissue density0.20.21.10.60.41.0-0.1-0.5-0.0-0.2-0.40.3
Condit. Reinf. active minus inactive responses0.20.20.30.50.40.5-0.5-0.60.40.4-0.20.6
Condit. Reinf. active-inactive response ratio0.10.10.30.30.20.5-0.1-0.3-0.1-0.20.1-0.0
Condit. Reinf. active responses0.00.00.30.00.0-0.2-0.1-0.00.00.20.20.5
Condit. Reinf. inactive responses0.20.21.0-0.6-0.4-1.00.20.6-0.20.10.3-0.0
Incentive salience index mean0.40.51.00.60.50.4-0.7-0.70.70.8-0.51.0
Condit. Reinf. lever presses0.40.61.80.60.70.1-0.8-0.50.81.0-0.61.3
Condit. Reinf. active minus inactive responses0.20.20.6-0.4-0.3-0.80.40.8-0.5-0.40.30.1
Condit. Reinf. active-inactive response ratio0.81.33.5-1.2-0.9-1.91.01.6-1.0-0.80.7-0.3
Condit. Reinf. active responses0.00.10.30.30.30.0-0.10.10.10.2-0.10.6
Condit. Reinf. inactive responses0.60.91.91.10.91.4-0.9-1.10.90.8-0.70.7
Condit. Reinf. lever presses1.21.82.71.51.60.7-1.4-0.81.41.6-1.11.6
Condit. Reinf. lever reinforcers received0.20.20.60.60.70.3-0.4-0.20.30.4-0.20.8
Conditioned reinforcement - actives0.00.20.6-0.1-0.0-0.80.40.8-0.4-0.20.2-0.0
Conditioned reinforcement - inactives1.54.06.0-1.9-1.9-2.32.22.4-2.1-1.72.30.2
Conditioned locomotion7.911.715.4-3.5-3.5-3.33.83.8-3.6-3.33.9-1.3
Patch foraging indifference point 0 sec0.10.21.7-0.1-0.3-0.10.10.2-0.2-0.10.11.3
Patch foraging indifference point AUC1.02.44.12.02.01.5-1.7-1.41.41.4-1.01.3
Delay disc. indifference point, 0s delay0.20.20.4-0.4-0.2-0.5-0.5-0.30.50.5-0.6-0.6
Delay disc. indifference point, 16s delay0.50.71.2-0.8-0.7-0.90.81.1-0.8-0.61.00.6
Delay disc. indifference point, 2s delay0.10.10.4-0.3-0.1-0.6-0.2-0.00.20.3-0.1-0.3
Delay disc. indifference point, 24s delay0.00.00.20.1-0.00.5-0.1-0.20.00.10.20.4
Delay disc. indifference point, 4s delay0.20.20.50.0-0.00.2-0.6-0.70.60.6-0.60.4
Delay disc. indifference point, 8s delay0.10.20.70.0-0.00.2-0.5-0.50.50.4-0.8-0.7
Indifference point function ln k2.88.513.5-3.6-3.7-2.72.92.7-2.8-2.82.1-2.5
Indifference point function log k2.88.513.5-3.6-3.7-2.72.92.7-2.8-2.82.1-2.5
Patch foraging total patch changes 0 sec0.10.21.50.0-0.20.30.0-0.1-0.1-0.1-0.01.2
Patch foraging total patch changes 12 sec4.86.49.72.72.52.3-2.6-2.22.42.4-2.23.1
Patch foraging total patch changes 18 sec0.41.01.41.21.10.9-1.1-0.90.80.8-1.00.9
Patch foraging total patch changes 24 sec1.13.610.12.01.81.8-1.7-1.71.61.8-1.03.2
Patch foraging total patch changes 6 sec1.11.83.21.31.21.1-1.4-1.31.41.4-1.01.8
Patch foraging time to switch 0 sec0.62.24.01.31.70.4-1.7-1.01.72.0-1.61.3
Patch foraging water rate 0 sec1.55.88.2-2.4-2.8-1.52.82.0-2.8-2.92.6-1.4
Patch foraging water rate 12 sec2.710.814.8-3.5-3.8-2.13.82.7-3.6-3.73.5-2.4
Patch foraging water rate 18 sec1.43.05.3-2.1-2.3-1.32.01.5-1.8-1.81.5-1.1
Patch foraging water rate 24 sec3.04.36.6-2.3-2.6-1.52.31.6-2.2-2.32.0-1.6
Patch foraging water rate 6 sec3.14.57.1-2.4-2.7-1.32.41.6-2.4-2.52.0-1.3
Seeking ratio, delayed vs. immediate footshock0.10.20.4-0.5-0.4-0.30.60.3-0.5-0.40.30.6
Distance traveled before self-admin0.40.82.40.91.00.2-0.9-0.50.91.1-0.51.5
Distance traveled after self-admin0.10.20.50.70.60.7-0.1-0.30.20.10.10.5
Extensor digitorum longus weight7.831.034.55.75.94.7-5.8-5.55.85.8-5.55.4
Bone: elastic displacement0.60.71.4-0.8-1.00.00.90.4-1.0-1.20.7-1.0
Bone: elastic work1.31.82.71.21.01.6-1.2-1.61.21.1-1.61.2
Bone: endosteal estimation0.61.56.0-1.6-1.2-2.40.61.5-0.4-0.00.4-0.6
Bone: endosteal perimeter1.02.58.9-1.9-1.4-3.01.02.0-0.8-0.31.0-1.0
Epididymis fat weight1.99.615.8-3.5-3.4-4.03.13.7-3.1-2.62.7-0.4
Delta time in closed arm before/after self-admin0.60.61.70.30.20.8-0.9-0.90.60.6-0.81.3
Delta time in open arm before/after self-admin0.20.31.10.80.70.2-0.1-0.20.30.40.31.1
Diff in mean of infusions in LGA sessions0.61.12.11.11.11.0-1.0-0.90.80.8-1.31.4
Delay discount exponential model param0.10.20.4-0.2-0.2-0.20.60.5-0.6-0.60.5-0.3
Extinction: sum of active levers before priming1.82.83.51.71.81.3-1.8-1.61.81.9-1.31.8
Active lever presses in extinction session 63.13.14.42.12.11.3-1.9-1.51.81.8-1.61.6
Bone: final force2.44.05.31.92.11.2-2.1-1.62.12.3-2.22.1
Bone: final moment2.43.95.11.92.01.2-2.0-1.62.12.3-2.22.2
Food consumed during 24 hour testing period0.10.10.40.20.20.20.30.2-0.3-0.30.60.6
Glucose2.03.16.1-2.3-2.2-2.51.41.7-1.3-1.11.3-1.5
Heart weight0.30.51.6-1.2-1.1-1.2-0.00.30.10.2-0.2-0.2
Delay discount hyperbolic model param0.10.20.4-0.1-0.2-0.00.60.5-0.6-0.60.5-0.2
Intermittent access intake day 1-15 change0.42.12.8-1.2-1.2-1.31.61.7-1.6-1.61.6-1.0
Intermittent access intake escalation0.31.92.5-1.1-1.1-1.31.51.6-1.5-1.51.5-1.2
Intermittent access intake escalation 21.01.62.5-1.0-1.1-1.31.41.5-1.5-1.31.6-0.4
Intermitt. access day 1 inactive lever presses0.00.51.8-0.4-0.5-0.40.60.7-0.6-0.80.6-1.3
Intermitt. access day 15 inactive lever presses0.63.45.5-1.8-1.7-2.31.82.3-1.9-1.42.01.1
Intermitt. access escalation Index0.92.73.8-1.9-1.9-1.32.01.6-1.8-1.81.4-0.9
Intermittent access day 1 total infusions1.23.510.1-2.4-2.0-3.21.62.3-1.4-0.81.20.1
Intermittent access day 15 total infusions3.27.913.9-3.1-2.8-3.72.83.4-2.7-2.22.6-1.2
Intermittent access terminal intake (last 3 days)3.46.014.1-2.8-2.5-3.82.43.0-2.2-1.62.0-0.1
Intermittent access total infusions4.04.811.9-2.6-2.3-3.42.02.7-1.8-1.31.7-0.1
Intermittent access day 1 locomotion1.32.46.2-2.0-1.7-2.51.31.9-1.2-0.71.20.4
Intermittent access day 15 total locomotion1.56.011.5-2.6-2.4-3.42.53.1-2.3-1.82.30.1
Intermittent access total locomotion7.08.418.3-3.2-2.9-4.32.83.6-2.7-1.92.60.5
Intermittent access standard deviation0.42.13.2-1.5-1.5-1.61.51.6-1.5-1.41.8-0.3
Left kidney weight0.21.74.1-1.6-1.5-2.01.21.5-1.0-0.71.1-0.3
Right kidney weight0.21.12.3-1.3-1.2-1.51.01.2-0.9-0.71.0-0.2
Cocaine induced anxiety0.00.00.00.20.2-0.1-0.00.10.10.00.2-0.1
Post-drug Anxiety0.40.50.70.70.90.4-0.8-0.50.70.7-0.70.5
Baseline Anxiety0.30.50.70.60.60.8-0.7-0.70.60.6-0.80.7
Tail length0.42.04.51.61.32.1-1.5-1.81.10.9-1.00.8
Length with tail1.98.610.53.13.03.0-3.2-3.23.02.8-2.82.2
Length without tail1.47.27.92.62.62.6-2.7-2.82.72.6-2.72.8
Times rat made contact with spout0.50.61.50.90.81.2-0.7-1.00.70.5-0.60.3
Lifetime Intake2.73.38.5-2.3-2.0-2.91.62.2-1.5-1.01.2-0.1
Liver weight, left0.50.91.6-1.3-1.2-1.10.80.7-0.8-0.80.5-1.3
Liver weight, right1.11.93.9-2.0-1.9-1.51.11.2-1.1-1.00.9-1.4
Locomotor activity1.32.03.7-1.6-1.9-0.81.61.0-1.5-1.71.0-1.2
Locomotor testing distance0.92.34.7-1.8-2.2-0.91.61.0-1.6-1.71.2-1.0
Locomotor testing rearing0.52.04.0-1.8-2.0-1.01.41.1-1.5-1.61.1-1.1
Locomotion in novel chamber5.06.78.9-2.8-3.0-2.92.83.0-2.6-2.42.3-1.0
Locomotion in novel chamber post-restriction1.64.85.7-2.3-2.3-2.32.32.4-2.3-2.21.9-1.6
Fecal boli incidents, locomotor time 10.00.00.10.20.4-0.4-0.10.2-0.00.10.20.0
Change in fecal boli incidents, locomotor task0.30.31.8-0.4-0.50.0-0.0-0.20.2-0.0-0.4-1.3
Time >=10cm from walls, locomotor time 10.81.03.7-1.1-0.7-1.90.71.3-0.6-0.40.7-0.8
Bouts of movement, locomotor time 10.81.03.61.61.31.9-0.5-1.00.30.1-0.10.2
Total resting periods, locomotor time 10.50.62.21.31.01.5-0.2-0.70.1-0.10.20.3
Rest time, locomotor task time 11.52.43.0-1.4-1.4-1.21.61.5-1.7-1.71.7-1.6
Distance moved, locomotor task time 10.20.61.80.40.40.1-0.7-0.60.91.0-1.30.7
Vertical activity count, locomotor time 10.10.81.4-1.2-1.1-1.20.80.9-0.7-0.70.2-0.8
Time >=10cm from walls, locomotor time 20.00.10.40.20.2-0.20.20.3-0.3-0.30.6-0.2
Bouts of movement, locomotor time 20.10.51.40.80.70.8-0.4-0.50.40.4-0.31.2
Total resting periods, locomotor time 20.00.20.70.50.40.5-0.2-0.20.20.2-0.10.9
Rest time, locomotor task time 21.93.24.0-2.0-1.9-1.91.71.9-1.6-1.61.4-1.9
Distance moved, locomotor task time 21.01.42.11.41.31.5-1.1-1.31.10.9-1.10.5
Vertical activity count, locomotor time 20.00.10.40.1-0.00.60.1-0.4-0.1-0.3-0.1-0.6
Light reinforcement 10.00.20.4-0.2-0.30.00.30.4-0.6-0.60.60.1
Light reinforcement 20.92.14.6-1.3-1.1-1.91.42.1-1.6-1.21.40.2
Bone: marrow area0.71.66.2-1.7-1.3-2.50.71.5-0.5-0.10.5-0.8
Bone: maximum diameter0.10.30.70.30.6-0.5-0.40.20.50.7-0.10.8
Bone: maximum force2.85.68.82.12.40.9-2.5-1.72.63.0-2.62.8
Bone: maximum moment2.85.48.22.02.30.9-2.5-1.72.52.9-2.62.8
Mean time between licks in bursts0.10.81.60.70.51.3-0.8-1.20.80.6-1.10.3
Mean num. licks in bursts0.00.10.3-0.3-0.50.10.30.1-0.4-0.50.3-0.3
Cd content in liver1.31.52.3-1.1-1.0-1.41.31.5-1.2-1.11.3-1.1
Co content in liver1.01.22.4-0.8-1.10.21.20.4-1.2-1.51.3-1.4
Cu content in liver0.10.10.1-0.1-0.10.10.20.1-0.3-0.40.4-0.4
Fe content in liver0.20.20.50.40.50.1-0.7-0.40.70.7-0.3-0.4
K content in liver1.01.01.60.70.70.6-1.2-1.11.21.3-0.80.8
Mg content in liver0.10.10.3-0.5-0.5-0.30.10.0-0.10.00.40.2
Mn content in liver2.62.94.31.92.11.3-1.7-1.41.61.7-1.32.1
Na content in liver0.40.50.90.70.70.7-0.7-0.70.60.7-0.31.0
Rb content in liver1.61.93.0-1.7-1.7-1.31.21.1-1.3-1.30.8-1.6
Se content in liver0.30.40.9-0.3-0.2-0.80.60.8-0.6-0.41.00.5
Sr content in liver2.72.33.81.81.71.6-1.4-1.51.31.3-1.01.9
Zn content in liver0.60.82.60.80.80.9-0.7-0.90.60.70.21.6
Bone: minimum diameter0.71.34.6-1.5-1.1-2.20.71.4-0.6-0.10.7-0.3
Time in familiar zone, hab. session 10.20.20.4-0.5-0.5-0.50.30.4-0.3-0.2-0.10.7
Time in novel zone, hab. session 10.30.32.2-0.4-0.4-0.10.2-0.0-0.2-0.30.5-1.5
Total zone transitions, hab. session 10.30.50.70.80.90.6-0.7-0.60.80.7-0.40.5
Total locomotion distance, hab. session 10.30.51.3-0.9-0.7-1.10.50.8-0.4-0.20.6-0.0
Locomotion velocity, hab. session 10.10.10.3-0.3-0.2-0.50.20.3-0.00.10.40.4
Time in familiar zone, hab. session 20.30.30.80.30.20.9-0.5-0.80.40.2-0.8-0.5
Time in novel zone, hab. session 20.10.10.6-0.00.1-0.40.10.3-0.00.20.50.8
Total zone transitions, hab. session 21.21.62.81.01.10.6-1.5-1.11.51.7-1.31.2
Total locomotion distance, hab. session 20.10.10.3-0.3-0.2-0.5-0.3-0.00.40.6-0.30.3
Locomotion velocity, hab. session 20.10.20.8-0.6-0.4-0.9-0.10.30.10.4-0.10.2
Novel to familiar place preference ratio0.71.02.71.11.20.4-0.8-0.40.91.0-0.71.6
Novelty place preference0.30.41.60.80.80.1-0.4-0.10.50.6-0.31.3
Time in novel zone, NPP test0.30.41.70.70.70.1-0.4-0.20.50.6-0.31.3
Total zone transitions, NPP test2.02.93.71.71.81.2-1.9-1.61.91.9-1.71.6
Total locomotion distance, NPP test0.10.10.3-0.10.0-0.3-0.3-0.10.40.5-0.30.4
Locomotion velocity, NPP test0.00.00.1-0.00.1-0.2-0.3-0.10.30.4-0.20.1
Intraocular pressure1.22.04.2-0.8-1.0-0.71.71.4-1.8-1.82.0-0.5
Delta distance traveled before/after self-admin0.30.30.9-0.3-0.40.50.60.0-0.5-0.70.5-0.9
Delta ambulatory time before/after self-admin0.20.31.5-0.1-0.20.50.4-0.2-0.2-0.50.4-1.2
Parametrial fat weight2.96.711.5-3.0-2.8-3.42.53.1-2.3-1.92.5-1.0
Pavlov. Cond. lever latency0.50.61.8-0.6-0.6-0.40.70.6-0.7-0.80.8-1.3
Pavlov. Cond. magazine entry latency0.50.62.30.60.70.1-0.7-0.40.81.0-0.51.5
Pavlov. Cond. change in total contacts0.10.10.70.30.4-0.2-0.00.20.00.20.30.9
Pavlov. Cond. index score0.30.41.50.70.70.5-0.5-0.40.50.6-0.41.2
Pavlov. Cond. latency score0.30.31.20.60.50.3-0.5-0.40.50.6-0.51.1
Pavlov. Cond. lever contacts0.30.31.10.40.40.2-0.5-0.50.60.7-0.61.0
Pavlov. Cond. magazine entry number0.30.41.5-0.8-0.8-0.60.40.4-0.4-0.40.2-1.2
Pavlov. Cond. intertrial magazine entries0.91.01.9-0.7-0.8-0.51.21.0-1.4-1.41.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.50.61.80.90.80.6-0.7-0.60.70.8-0.51.3
Pavlov. Cond. response bias0.30.42.00.70.60.4-0.4-0.30.30.5-0.21.4
Pavlov. Cond. lever latency0.40.62.0-0.8-0.9-0.20.60.3-0.7-0.90.5-1.4
Pavlov. Cond. magazine entry latency3.95.57.22.62.62.0-2.3-2.02.32.4-2.02.7
Pavlov. Cond. change in total contacts0.71.64.71.41.60.5-1.0-0.51.11.3-0.82.2
Pavlov. Cond. index score1.92.95.61.92.01.0-1.6-1.11.71.9-1.42.4
Pavlov. Cond. latency score1.52.45.01.71.80.8-1.5-1.01.51.7-1.22.2
Pavlov. Cond. lever contacts0.40.61.70.90.90.3-0.7-0.30.70.9-0.61.3
Pavlov. Cond. magazine entry number6.07.811.0-3.1-3.2-2.32.72.3-2.7-2.82.3-3.3
Pavlov. Cond. intertrial magazine entries0.71.52.9-1.2-1.3-1.01.21.1-1.2-1.30.9-1.7
Pavlov. Cond. lever-magazine prob. diff.2.33.66.52.12.21.3-1.8-1.31.82.0-1.52.6
Pavlov. Cond. response bias1.92.65.01.81.91.1-1.5-1.11.61.8-1.32.2
Time in closed arm before self-admin0.30.51.2-0.6-0.6-1.00.81.1-0.6-0.40.9-0.3
Time in closed arm after self-admin0.40.40.7-0.8-0.8-0.60.60.7-0.6-0.60.5-0.6
Time in open arm before self-admin0.20.20.5-0.3-0.40.7-0.2-0.7-0.0-0.3-0.6-0.7
Time in open arm after self-admin0.30.30.80.60.40.9-0.4-0.90.50.3-0.50.4
Bone: periosteal estimation0.10.31.5-0.4-0.0-1.2-0.20.50.30.7-0.30.5
Bone: periosteal perimeter0.10.20.70.10.3-0.7-0.40.10.60.8-0.40.4
Bone: post-yield work0.61.02.50.00.5-1.6-0.90.51.01.6-0.90.9
Progressive ratio test 1 active lever presses0.30.51.5-0.8-0.7-1.20.70.8-0.5-0.30.6-0.4
Progressive ratio test 1 breakpoint0.30.41.4-0.8-0.6-1.20.60.8-0.4-0.30.6-0.4
Progressive ratio test 1 inactive lever presses0.10.21.1-0.2-0.4-0.40.50.5-0.2-0.10.41.0
Progressive ratio test 2 active lever presses2.53.56.5-2.0-1.8-2.51.92.3-1.8-1.41.8-0.4
Progressive ratio test 2 breakpoint2.83.56.4-2.0-1.8-2.52.02.3-1.9-1.41.9-0.3
Progressive ratio test 2 inactive lever presses3.410.714.7-3.4-3.4-3.83.63.8-3.4-2.93.2-0.3
Incentive Sensitization - Responses0.10.42.1-0.3-0.1-0.90.10.6-0.10.2-0.01.4
Incentive Sensitization - Breakpoint0.20.51.7-0.5-0.4-1.10.30.8-0.4-0.00.31.3
Sum of active levers in priming session hrs 5-60.40.41.41.21.00.8-0.1-0.20.10.10.30.5
Progressive ratio0.51.42.70.91.10.1-1.4-1.01.51.6-1.21.0
Food seeking constrained by brief footshock0.10.10.20.20.20.4-0.4-0.50.40.4-0.1-0.1
Seeking ratio, punishment vs. effort0.61.32.0-1.1-1.3-0.11.20.7-1.3-1.41.3-1.0
Retroperitoneal fat weight7.432.945.2-6.7-6.7-6.15.96.0-5.7-5.35.1-3.3
Reaction time number correct0.10.40.70.70.50.8-0.5-0.70.50.4-0.50.8
Reaction time mean minus median0.63.65.82.22.41.4-2.0-1.51.91.9-2.20.8
Reaction time mean minus median AUC0.31.82.91.71.71.3-1.4-1.21.31.2-1.60.4
Reaction time num false alarms0.20.30.7-0.6-0.90.30.3-0.1-0.5-0.7-0.0-0.8
Reaction time num false alarms AUC0.10.20.80.1-0.20.9-0.4-0.80.2-0.1-0.6-0.3
Reaction time trials correct on left0.10.40.70.70.50.8-0.5-0.70.50.4-0.50.8
Reaction time trials on left0.10.50.80.80.60.9-0.6-0.70.50.4-0.60.8
Reaction time mean0.00.00.20.10.2-0.20.10.3-0.0-0.0-0.0-0.4
Reaction time mean AUC0.00.10.20.10.1-0.30.10.4-0.1-0.10.1-0.5
Median of all reaction times0.20.30.6-0.5-0.5-0.70.60.7-0.5-0.40.6-0.5
Reaction time omissions0.81.32.01.41.41.2-1.0-0.91.11.0-1.30.3
Reaction time false alarm rate0.10.20.6-0.5-0.70.10.2-0.1-0.3-0.5-0.1-0.8
Reaction time premature initiation rate2.94.55.72.01.92.3-2.3-2.42.12.1-1.92.1
Reaction time premature initiations2.16.28.82.62.43.0-2.6-2.82.42.2-2.02.4
Std. dev. reaction times0.20.71.51.11.20.7-0.9-0.50.70.6-1.1-0.4
Reaction time trials completed0.10.50.80.80.60.9-0.6-0.70.50.4-0.60.8
Reaction time trials AUC0.10.30.50.60.40.7-0.5-0.60.40.3-0.50.7
Run reversals in cocaine runway, females0.70.81.50.30.40.4-1.0-0.81.11.2-1.21.0
Run reversals in cocaine runway, males0.20.20.8-0.4-0.4-0.20.50.1-0.3-0.40.1-0.9
Latency to leave start box in cocaine runway0.20.20.8-0.6-0.4-0.90.10.5-0.2-0.00.6-0.3
Latency to leave start box in cocaine runway, F0.00.10.2-0.1-0.1-0.3-0.00.1-0.10.00.50.3
Latency to leave start box in cocaine runway, M0.20.21.3-0.4-0.1-0.6-0.20.30.10.2-0.0-1.2
Std. dev. time between licks in bursts0.10.10.4-0.1-0.20.6-0.2-0.50.1-0.0-0.4-0.4
Total sessions with >9 infusions0.20.20.8-0.5-0.3-0.9-0.10.50.10.2-0.7-0.5
Short access day 1 total inactive lever presses1.63.24.7-2.2-2.1-2.01.92.0-1.8-1.61.4-0.3
Short access day 10 total inactive lever presses0.10.91.9-0.8-0.9-0.40.80.6-0.9-1.11.1-1.4
Short access day 1 total infusions1.02.04.1-1.9-1.7-2.01.21.6-1.2-1.00.6-0.9
Short access day 10 total infusions0.60.94.1-1.3-0.9-2.00.41.2-0.20.1-0.20.2
Short access total infusions0.50.83.1-1.3-1.0-1.80.41.0-0.20.0-0.2-0.2
Short access day 1 locomotion1.01.62.9-1.6-1.5-1.71.21.6-1.2-1.00.8-0.1
Short access day 10 total locomotion0.31.33.2-1.3-1.1-1.81.01.5-0.9-0.51.10.5
Short access total locomotion1.31.94.4-1.6-1.5-2.11.31.8-1.1-0.81.10.2
One hour access (0.3 mA shock)6.27.410.2-3.0-2.9-3.22.83.2-2.7-2.32.7-0.2
Compulsive drug intake1.92.87.11.81.62.7-1.7-2.21.41.0-1.00.5
One hour access (shock baseline)3.910.215.7-3.4-3.2-4.03.43.8-3.1-2.63.1-1.2
Social response proportion0.50.60.90.90.90.7-0.9-0.60.80.8-0.70.5
Social responses0.40.51.00.90.51.0-0.7-1.00.60.4-0.70.3
Social time0.30.50.80.80.60.9-0.7-0.80.70.5-0.8-0.1
Soleus weight3.911.614.3-3.7-3.8-3.13.63.3-3.5-3.52.8-3.2
Bone: stiffness1.62.94.21.72.00.7-1.9-1.21.92.1-2.01.4
Tibialis anterior weight9.733.540.16.36.35.4-5.8-5.85.85.7-5.15.7
Time to tail flick, vehicle, before self-admin0.30.41.00.30.5-0.3-0.8-0.20.81.0-0.80.6
Time to tail flick, vehicle, after self-admin1.22.44.01.01.20.6-1.9-1.51.92.0-2.01.0
Time to tail flick, test, before self-admin1.11.32.6-1.6-1.6-1.61.11.2-0.7-0.50.40.8
Time to tail flick, test, after self-admin0.10.10.20.40.30.1-0.4-0.20.40.3-0.30.4
Delta time to tail flick, vehicle, before/after SA0.91.01.60.80.80.8-1.2-1.31.11.1-1.10.6
Delta time to tail flick, test, before/after SA0.91.12.91.71.51.6-0.9-1.00.60.3-0.1-0.1
Tibia length0.61.84.81.71.80.7-1.1-0.71.01.3-0.62.2
Ambulatory time before self-admin0.20.51.90.80.80.0-0.7-0.20.60.9-0.41.4
Ambulatory time after self-admin0.30.51.8-0.4-0.3-0.50.80.7-0.6-0.51.30.1
Bone: tissue strength0.00.00.1-0.1-0.1-0.20.20.3-0.3-0.30.0-0.3
Total heroin consumption5.05.98.32.92.82.6-2.3-2.52.42.2-2.21.7
Bone: trabecular number0.71.43.60.91.20.1-1.2-0.61.31.5-1.01.9
Bone: trabecular spacing0.40.61.6-0.6-0.80.10.70.2-0.8-1.10.4-1.3
Bone: trabecular thickness0.40.51.2-0.9-0.8-1.10.70.9-0.6-0.50.3-0.2
Bone: trabecular tissue density3.66.39.6-2.4-2.5-1.92.62.4-2.7-2.81.9-3.1
Water consumed over 24 hours0.71.42.81.41.31.7-1.0-1.30.90.7-0.81.1
Number of responses in last shaping day0.00.00.20.0-0.10.40.10.0-0.1-0.1-0.00.5