Hub : Genes

Rbm14

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio NM_133388.1 0.03 0.02 6.3e-03 0.02 0.01 -0 0.01 2.2e-03 3.9e-02 4.5e-01 1.3e-02
2 NAcc alternative polyA XM_039084944.1 0.02 0.01 5.5e-03 0 0.01 0.01 0 6.9e-02 1.1e-02 2.1e-02 6.8e-02
3 NAcc alternative polyA XM_039084944.1 0.03 0.02 1.5e-03 0.01 0.02 0.01 0.01 3.3e-02 2.7e-03 1.1e-02 1.3e-02
4 NAcc alternative polyA XM_039084962.1 0.02 0.01 8.1e-03 0.01 0.01 0.01 0.01 3.0e-02 9.9e-03 1.7e-02 3.2e-02
5 IL isoform ratio NM_133388.1 0.37 0.2 1.8e-03 0.02 0.05 0.15 0.1 1.2e-01 2.3e-02 1.6e-04 2.5e-03
6 Brain intron excision ratio chr1_202078683_202086011 0.03 0.02 6.5e-03 0 0 0 0 1.9e-01 2.2e-01 1.8e-01 2.8e-01
7 pVTA alternative TSS XM_039084839.1 0.08 0.06 9.0e-03 0.02 0.04 0.02 0.03 4.2e-02 1.1e-02 6.6e-02 3.0e-02
8 pVTA alternative TSS XM_039084944.1 0.08 0.06 8.6e-03 0.02 0.04 0.02 0.03 3.7e-02 1.2e-02 3.5e-02 2.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density1.42.46.51.1-0.3-0.50.62.10.52.5-2.6
Area under the delay curve0.91.02.0-0.6-0.9-0.91.0-0.41.41.2-1.2
BMI with tail1.65.311.82.71.10.8-0.63.2-0.23.3-3.4
BMI without tail0.61.23.01.40.50.4-0.21.1-0.21.7-1.7
Body weight1.97.915.84.03.43.3-3.13.0-2.30.6-0.8
Weight adjusted by age2.22.54.01.92.01.9-1.92.0-0.9-0.60.4
Bone surface2.95.115.82.91.51.4-1.24.0-1.32.1-2.2
Bone volume1.72.910.51.80.50.4-0.23.2-0.42.1-2.2
Breakpoint value in progressive ratio session2.52.84.91.82.02.0-1.92.2-1.7-0.20.1
Number of licking bursts0.20.20.60.50.50.5-0.40.8-0.20.1-0.2
Context. condit. distance diff. score1.41.72.5-1.6-1.6-1.61.5-1.31.30.2-0.1
Locomotion velocity, session 10.20.20.6-0.20.20.2-0.3-0.80.5-0.70.7
Locomotion distance, session 10.60.72.10.30.1-0.00.10.90.91.4-1.5
Locomotion velocity, session 21.41.73.31.81.61.5-1.41.5-0.90.3-0.4
Locomotion distance, session 20.40.51.10.70.60.5-0.40.80.31.0-1.0
Locomotion velocity, session 30.30.40.7-0.4-0.5-0.60.60.10.70.8-0.8
Locomotion distance, session 30.00.00.0-0.1-0.1-0.10.1-0.10.10.0-0.0
Stereotopy head waving bouts, day 31.01.21.7-1.1-1.2-1.31.3-0.61.30.9-0.9
Stereotopy head waving duration, day 31.21.42.1-1.2-1.4-1.51.5-0.31.40.9-0.8
Locomotion velocity, session 70.70.81.5-0.4-0.9-1.01.00.30.71.2-1.2
Locomotion distance, session 70.10.10.30.1-0.2-0.30.3-0.30.20.6-0.5
Stereotopy head waving bouts, day 70.50.61.0-0.1-0.8-0.80.90.90.21.0-1.0
Stereotopy head waving duration, day 71.11.33.91.40.30.3-0.22.0-0.71.4-1.5
Locomotion velocity, session 80.60.71.40.81.21.2-1.20.1-0.6-0.50.4
Locomotion distance, session 80.30.51.2-0.7-0.7-0.70.7-0.11.10.5-0.5
Degree of sensitization distance0.20.20.60.2-0.2-0.30.3-0.00.40.8-0.8
Degree of sensitization stereotypy0.80.92.91.20.30.3-0.31.7-1.10.7-0.8
Conditioned locomotion1.92.23.21.61.81.8-1.80.3-1.7-1.01.0
Cocaine response after cond. corrected0.91.03.0-1.0-1.1-1.11.0-1.70.8-0.00.1
Cocaine response after cond. not corrected0.80.91.8-1.0-1.1-1.11.1-1.31.10.3-0.2
Cocaine response before conditioning0.50.62.40.80.60.6-0.51.6-0.20.4-0.5
Saline control response1.72.34.42.11.91.8-1.71.6-0.80.4-0.5
Bone: connectivity density2.03.18.02.00.70.6-0.42.8-0.52.3-2.5
Bone: cortical apparent density0.30.30.50.50.70.7-0.7-0.2-0.7-0.40.4
Bone: cortical area1.01.52.11.31.41.4-1.41.1-1.5-0.80.8
Bone: cortical porosity0.40.41.10.0-0.2-0.30.40.60.51.0-1.0
Bone: cortical porosity0.30.30.70.60.30.2-0.10.70.00.8-0.8
Bone: cortical thickness4.26.910.32.73.23.2-3.20.5-3.0-2.12.0
Bone: cortical thickness1.82.12.81.21.61.6-1.7-0.9-1.5-1.51.5
Bone: cortical tissue density0.30.40.60.60.80.8-0.8-0.2-0.8-0.50.5
Condit. Reinf. active minus inactive responses0.20.20.30.40.20.2-0.20.40.50.5-0.5
Condit. Reinf. active-inactive response ratio0.10.10.30.00.00.0-0.00.30.50.3-0.4
Condit. Reinf. active responses0.10.10.20.50.20.2-0.20.50.30.3-0.3
Condit. Reinf. inactive responses0.00.00.10.3-0.1-0.10.10.3-0.00.2-0.2
Incentive salience index mean0.20.20.40.60.30.3-0.30.60.40.6-0.7
Condit. Reinf. lever presses0.20.30.50.70.60.6-0.60.6-0.4-0.10.0
Condit. Reinf. active minus inactive responses0.60.81.3-0.5-0.8-0.80.81.10.81.0-1.0
Condit. Reinf. active-inactive response ratio0.80.81.1-1.1-1.1-1.01.01.00.90.6-0.5
Condit. Reinf. active responses0.81.22.80.1-0.5-0.60.71.40.81.7-1.7
Condit. Reinf. inactive responses0.70.93.00.8-0.0-0.20.30.60.21.7-1.7
Condit. Reinf. lever presses1.72.37.01.91.41.4-1.32.6-1.20.7-0.9
Condit. Reinf. lever reinforcers received0.71.02.70.4-0.2-0.20.31.60.41.5-1.6
Conditioned reinforcement - actives0.10.10.3-0.5-0.2-0.20.20.4-0.3-0.40.4
Conditioned reinforcement - inactives2.83.26.8-2.6-2.4-2.32.2-0.51.50.00.1
Conditioned locomotion4.35.112.2-3.5-2.7-2.52.4-2.11.7-0.81.0
Patch foraging indifference point 0 sec0.10.20.2-0.2-0.5-0.50.50.00.30.5-0.5
Patch foraging indifference point AUC3.03.55.42.32.12.1-2.02.2-2.1-0.40.2
Delay disc. indifference point, 0s delay1.81.94.3-1.2-1.3-1.41.4-1.32.11.1-1.1
Delay disc. indifference point, 16s delay1.31.31.9-1.2-1.3-1.31.40.11.31.1-1.0
Delay disc. indifference point, 2s delay0.30.30.6-0.4-0.6-0.60.6-0.40.80.5-0.4
Delay disc. indifference point, 24s delay0.20.21.2-0.2-0.1-0.10.1-1.10.4-0.30.3
Delay disc. indifference point, 4s delay0.80.81.4-0.7-0.8-0.90.9-1.11.20.9-0.8
Delay disc. indifference point, 8s delay0.60.61.3-0.5-0.6-0.70.7-0.81.20.8-0.8
Indifference point function ln k6.28.615.2-3.8-3.2-3.13.0-3.93.1-0.30.5
Indifference point function log k6.28.615.2-3.8-3.2-3.13.0-3.93.1-0.30.5
Patch foraging total patch changes 0 sec0.00.00.2-0.1-0.1-0.10.1-0.40.1-0.10.1
Patch foraging total patch changes 12 sec3.03.97.32.72.32.2-2.12.4-2.00.4-0.5
Patch foraging total patch changes 18 sec0.60.82.11.30.60.5-0.51.4-1.10.6-0.7
Patch foraging total patch changes 24 sec1.72.03.41.61.91.8-1.81.3-1.3-0.50.4
Patch foraging total patch changes 6 sec0.71.12.61.61.00.9-0.91.1-0.80.7-0.8
Patch foraging time to switch 0 sec1.52.36.01.80.90.8-0.62.5-0.71.8-1.9
Patch foraging water rate 0 sec2.54.08.5-2.7-1.7-1.51.3-2.91.1-1.92.1
Patch foraging water rate 12 sec5.78.821.6-4.0-2.7-2.52.3-4.72.4-1.82.0
Patch foraging water rate 18 sec2.53.47.4-2.6-1.7-1.61.5-2.71.9-0.70.8
Patch foraging water rate 24 sec2.94.09.8-2.7-1.7-1.61.4-3.11.4-1.51.7
Patch foraging water rate 6 sec2.94.213.3-2.6-1.4-1.31.2-3.71.6-1.61.8
Seeking ratio, delayed vs. immediate footshock0.50.61.2-0.1-0.5-0.50.60.41.11.1-1.1
Distance traveled before self-admin0.30.31.20.60.50.5-0.51.1-0.6-0.0-0.0
Distance traveled after self-admin0.20.31.30.40.40.4-0.41.2-0.5-0.10.0
Extensor digitorum longus weight4.819.034.25.85.55.3-5.23.6-4.4-0.60.3
Bone: elastic displacement1.21.44.6-1.0-0.1-0.0-0.1-2.1-0.1-1.61.7
Bone: elastic work1.51.92.71.11.61.6-1.6-0.7-1.4-1.41.4
Bone: endosteal estimation1.63.45.0-1.5-2.1-2.22.20.32.21.8-1.7
Bone: endosteal perimeter2.55.27.0-2.0-2.5-2.52.61.32.72.3-2.2
Epididymis fat weight1.94.58.2-2.5-2.9-2.82.8-1.41.80.8-0.7
Delta time in closed arm before/after self-admin0.30.31.10.70.50.5-0.5-1.0-0.4-0.40.4
Delta time in open arm before/after self-admin0.30.31.00.20.20.2-0.21.0-0.9-0.30.3
Diff in mean of infusions in LGA sessions0.80.91.90.91.01.0-1.00.8-1.4-0.60.6
Delay discount exponential model param0.70.71.70.50.70.8-0.80.4-1.3-1.01.0
Extinction: sum of active levers before priming3.03.05.92.21.91.8-1.72.4-1.60.5-0.6
Active lever presses in extinction session 63.13.04.21.72.02.1-2.11.3-2.1-1.31.2
Bone: final force1.62.64.82.21.91.9-1.82.0-1.30.0-0.1
Bone: final moment1.42.34.22.11.81.7-1.71.9-1.20.0-0.2
Food consumed during 24 hour testing period0.20.20.40.10.30.4-0.40.3-0.2-0.70.6
Glucose2.74.06.1-1.8-2.4-2.42.5-0.42.11.9-1.8
Heart weight2.23.15.3-1.8-2.3-2.32.3-1.81.40.8-0.7
Delay discount hyperbolic model param0.60.61.50.50.60.7-0.70.5-1.2-1.00.9
Intermittent access intake day 1-15 change0.30.31.1-0.5-0.10.0-0.10.2-0.2-1.01.0
Intermittent access intake escalation0.20.20.4-0.5-0.3-0.20.10.30.1-0.60.6
Intermittent access intake escalation 20.40.41.3-0.20.20.3-0.30.3-0.4-1.11.1
Intermitt. access day 1 inactive lever presses1.11.12.4-1.3-1.5-1.51.4-0.80.20.3-0.2
Intermitt. access day 15 inactive lever presses0.70.81.7-1.3-1.3-1.21.20.30.30.2-0.1
Intermitt. access escalation Index4.43.95.5-2.0-2.3-2.32.3-2.02.31.1-0.9
Intermittent access day 1 total infusions6.57.511.9-2.3-3.3-3.43.5-0.42.52.7-2.5
Intermittent access day 15 total infusions4.75.39.6-2.8-3.1-3.03.0-0.52.11.1-1.0
Intermittent access terminal intake (last 3 days)3.63.97.1-2.2-2.7-2.62.6-0.01.51.3-1.2
Intermittent access total infusions4.14.67.6-1.9-2.7-2.72.80.11.82.0-1.9
Intermittent access day 1 locomotion4.95.27.8-1.7-2.6-2.72.8-0.71.92.5-2.4
Intermittent access day 15 total locomotion3.23.45.9-2.2-2.4-2.42.4-0.11.71.1-1.0
Intermittent access total locomotion6.47.311.5-2.6-3.3-3.43.40.22.52.4-2.3
Intermittent access standard deviation0.30.30.8-0.9-0.7-0.60.6-0.30.1-0.40.4
Left kidney weight0.30.82.3-1.5-0.9-0.80.8-0.60.3-0.90.9
Right kidney weight0.20.72.1-0.80.00.1-0.20.2-0.7-1.41.5
Cocaine induced anxiety0.10.10.20.20.20.2-0.20.2-0.3-0.40.4
Post-drug Anxiety1.82.02.81.41.61.6-1.71.1-1.7-1.11.0
Baseline Anxiety2.22.33.61.61.91.9-1.91.0-1.6-0.90.7
Tail length1.33.85.81.02.22.2-2.3-0.7-1.5-2.42.3
Length with tail2.27.912.92.93.63.6-3.61.0-2.9-2.01.8
Length without tail1.94.16.82.52.62.6-2.51.7-1.9-0.50.4
Times rat made contact with spout0.20.30.50.60.40.3-0.30.50.20.7-0.7
Lifetime Intake3.94.47.2-1.7-2.6-2.62.7-0.11.82.1-2.0
Liver weight, left0.10.10.2-0.4-0.2-0.20.2-0.40.2-0.40.4
Liver weight, right0.10.20.8-0.5-0.2-0.20.2-0.90.6-0.20.2
Locomotor activity1.42.26.5-1.9-1.0-0.90.8-2.61.4-1.21.3
Locomotor testing distance2.03.410.5-2.3-1.3-1.21.1-3.22.0-1.11.3
Locomotor testing rearing1.72.64.9-1.8-1.8-1.81.7-2.21.80.3-0.2
Locomotion in novel chamber2.73.46.7-2.6-2.3-2.22.2-0.82.1-0.00.1
Locomotion in novel chamber post-restriction1.61.93.4-1.8-1.8-1.81.7-1.21.00.00.1
Fecal boli incidents, locomotor time 10.40.41.50.50.20.3-0.31.1-1.2-0.20.1
Change in fecal boli incidents, locomotor task0.50.52.0-0.3-0.3-0.30.4-0.61.40.7-0.7
Time >=10cm from walls, locomotor time 12.32.33.3-0.7-1.5-1.51.61.31.61.8-1.8
Bouts of movement, locomotor time 10.91.01.51.11.21.2-1.21.2-1.1-0.20.1
Total resting periods, locomotor time 10.70.71.80.90.90.9-0.91.3-1.00.1-0.2
Rest time, locomotor task time 10.90.92.1-1.5-1.0-0.90.9-1.20.7-0.60.7
Distance moved, locomotor task time 10.50.51.30.5-0.1-0.10.21.00.41.1-1.1
Vertical activity count, locomotor time 10.60.61.0-1.0-0.9-0.90.9-0.70.70.00.0
Time >=10cm from walls, locomotor time 20.10.10.3-0.3-0.1-0.10.10.50.30.2-0.2
Bouts of movement, locomotor time 20.40.41.01.00.70.7-0.60.7-0.70.2-0.3
Total resting periods, locomotor time 20.20.20.60.80.40.4-0.30.7-0.50.4-0.4
Rest time, locomotor task time 21.61.93.1-1.8-1.7-1.71.6-1.41.30.1-0.0
Distance moved, locomotor task time 20.70.91.61.01.31.3-1.20.9-0.5-0.30.2
Vertical activity count, locomotor time 20.91.02.3-0.10.80.8-0.9-1.0-0.3-1.51.5
Light reinforcement 10.10.20.6-0.8-0.5-0.50.5-0.50.5-0.20.2
Light reinforcement 20.40.61.9-1.4-0.9-0.80.80.10.5-0.40.5
Bone: marrow area1.63.65.2-1.5-2.2-2.22.30.22.31.8-1.7
Bone: maximum diameter0.20.31.70.20.40.5-0.51.3-0.4-0.30.3
Bone: maximum force2.03.510.52.41.61.5-1.43.2-1.01.2-1.4
Bone: maximum moment1.72.98.92.21.51.4-1.33.0-0.91.2-1.3
Mean time between licks in bursts0.20.30.70.30.70.7-0.7-0.80.4-0.30.3
Mean num. licks in bursts0.20.30.4-0.4-0.6-0.60.6-0.60.60.4-0.4
Cd content in liver0.50.61.1-1.1-0.9-0.80.8-0.40.3-0.60.7
Co content in liver1.41.66.1-1.2-0.6-0.50.4-2.50.7-1.31.4
Cu content in liver0.20.20.70.60.50.4-0.40.8-0.30.3-0.4
Fe content in liver0.20.20.40.40.50.5-0.50.5-0.6-0.40.4
K content in liver1.11.12.21.20.80.7-0.61.5-0.41.2-1.3
Mg content in liver1.91.95.60.2-0.6-0.80.91.30.92.3-2.4
Mn content in liver2.12.44.51.91.71.6-1.62.1-1.80.2-0.3
Na content in liver1.01.11.80.51.31.3-1.30.8-0.8-1.01.0
Rb content in liver2.12.64.0-1.1-1.9-2.02.0-0.41.61.6-1.6
Se content in liver0.60.83.40.1-0.3-0.40.41.8-0.11.0-1.1
Sr content in liver3.33.04.51.82.02.0-2.10.9-2.1-1.31.1
Zn content in liver0.70.81.41.21.11.0-1.00.9-0.80.2-0.3
Bone: minimum diameter1.83.34.9-1.0-1.9-2.02.10.91.72.2-2.2
Time in familiar zone, hab. session 10.60.50.8-0.8-0.7-0.70.80.20.90.8-0.8
Time in novel zone, hab. session 10.40.42.0-0.2-0.0-0.0-0.0-1.40.2-0.80.8
Total zone transitions, hab. session 10.30.50.80.90.90.9-0.80.9-0.20.2-0.3
Total locomotion distance, hab. session 10.30.40.8-0.7-0.8-0.80.7-0.40.90.3-0.3
Locomotion velocity, hab. session 10.10.10.2-0.2-0.3-0.30.3-0.10.40.3-0.3
Time in familiar zone, hab. session 20.30.31.20.10.30.3-0.4-1.1-0.1-0.70.7
Time in novel zone, hab. session 20.40.41.00.2-0.3-0.30.40.90.11.0-1.0
Total zone transitions, hab. session 21.82.37.11.00.0-0.10.31.80.72.6-2.7
Total locomotion distance, hab. session 21.01.33.0-0.3-0.9-1.01.00.31.21.7-1.7
Locomotion velocity, hab. session 21.11.53.0-0.5-1.0-1.11.20.41.31.7-1.7
Novel to familiar place preference ratio0.91.03.71.10.60.6-0.51.9-0.90.6-0.7
Novelty place preference0.60.62.50.70.20.2-0.11.6-0.60.7-0.8
Time in novel zone, NPP test0.40.51.80.60.10.1-0.01.4-0.50.7-0.8
Total zone transitions, NPP test0.81.23.01.21.11.0-0.91.7-0.10.9-1.0
Total locomotion distance, NPP test0.10.20.6-0.1-0.2-0.20.20.10.80.6-0.6
Locomotion velocity, NPP test0.10.10.4-0.2-0.0-0.10.10.30.60.4-0.5
Intraocular pressure0.40.51.3-0.4-0.4-0.30.2-0.2-1.1-1.11.1
Delta distance traveled before/after self-admin0.00.00.0-0.10.00.0-0.0-0.1-0.2-0.20.2
Delta ambulatory time before/after self-admin0.00.00.10.00.10.1-0.1-0.1-0.1-0.20.2
Parametrial fat weight2.14.07.3-2.1-2.7-2.72.7-0.51.41.4-1.2
Pavlov. Cond. lever latency0.10.10.3-0.5-0.3-0.30.2-0.60.4-0.30.3
Pavlov. Cond. magazine entry latency0.50.71.70.2-0.4-0.40.51.10.31.3-1.3
Pavlov. Cond. change in total contacts0.30.31.5-0.0-0.2-0.20.21.2-0.10.5-0.5
Pavlov. Cond. index score0.10.10.40.20.10.1-0.10.6-0.30.1-0.1
Pavlov. Cond. latency score0.00.10.20.1-0.1-0.10.10.4-0.10.3-0.3
Pavlov. Cond. lever contacts0.00.00.00.2-0.0-0.00.0-0.0-0.10.1-0.1
Pavlov. Cond. magazine entry number0.20.30.8-0.5-0.4-0.40.4-0.90.70.2-0.1
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.2-0.2-0.10.1-0.2-0.0-0.60.6
Pavlov. Cond. lever-magazine prob. diff.0.10.20.60.40.30.3-0.30.8-0.40.2-0.2
Pavlov. Cond. response bias0.10.10.30.30.20.3-0.30.5-0.5-0.10.1
Pavlov. Cond. lever latency0.50.72.2-0.9-0.7-0.70.7-1.51.0-0.20.3
Pavlov. Cond. magazine entry latency2.12.55.12.01.71.6-1.52.3-0.90.9-1.1
Pavlov. Cond. change in total contacts1.72.49.61.51.11.1-1.03.1-1.20.9-1.1
Pavlov. Cond. index score1.72.26.71.71.51.4-1.32.6-1.20.6-0.8
Pavlov. Cond. latency score1.51.85.71.51.41.3-1.22.4-1.00.5-0.7
Pavlov. Cond. lever contacts0.50.71.70.70.90.9-0.91.3-1.0-0.20.2
Pavlov. Cond. magazine entry number3.94.710.1-2.8-2.4-2.32.1-3.21.5-0.91.2
Pavlov. Cond. intertrial magazine entries0.60.81.4-1.2-1.2-1.11.1-0.90.7-0.20.3
Pavlov. Cond. lever-magazine prob. diff.2.12.67.21.91.61.6-1.52.7-1.30.7-0.8
Pavlov. Cond. response bias1.31.74.41.51.41.3-1.32.1-1.20.4-0.5
Time in closed arm before self-admin0.10.10.4-0.1-0.2-0.20.30.70.20.4-0.4
Time in closed arm after self-admin0.00.00.10.1-0.1-0.10.1-0.40.10.1-0.1
Time in open arm before self-admin0.70.73.7-0.7-0.5-0.50.5-1.91.0-0.00.1
Time in open arm after self-admin0.20.20.7-0.4-0.1-0.10.1-0.8-0.4-0.60.6
Bone: periosteal estimation0.10.21.00.1-0.3-0.30.31.00.20.4-0.4
Bone: periosteal perimeter0.30.52.60.2-0.1-0.10.21.60.20.8-0.8
Bone: post-yield work4.56.114.70.3-1.2-1.31.53.61.33.8-3.8
Progressive ratio test 1 active lever presses1.71.73.1-1.5-1.8-1.81.7-0.71.10.7-0.6
Progressive ratio test 1 breakpoint1.31.42.5-1.4-1.6-1.61.5-0.70.90.5-0.4
Progressive ratio test 1 inactive lever presses1.01.11.7-1.0-1.3-1.31.3-0.70.90.7-0.7
Progressive ratio test 2 active lever presses2.42.64.6-2.0-2.1-2.12.1-0.01.40.9-0.8
Progressive ratio test 2 breakpoint2.52.85.3-2.3-2.3-2.22.1-0.71.40.4-0.3
Progressive ratio test 2 inactive lever presses6.17.012.1-3.0-3.5-3.43.4-0.62.71.4-1.2
Incentive Sensitization - Responses0.40.40.8-0.5-0.7-0.60.70.90.20.6-0.6
Incentive Sensitization - Breakpoint0.40.40.6-0.7-0.8-0.80.80.70.30.5-0.5
Sum of active levers in priming session hrs 5-63.83.64.61.32.02.1-2.11.8-2.1-1.91.8
Progressive ratio1.71.94.51.60.50.3-0.21.9-0.12.0-2.1
Food seeking constrained by brief footshock0.20.20.50.70.70.6-0.6-0.2-0.1-0.30.3
Seeking ratio, punishment vs. effort1.51.85.1-1.6-0.5-0.40.3-2.30.8-1.61.7
Retroperitoneal fat weight3.812.421.1-4.6-4.5-4.44.4-2.63.31.1-0.8
Reaction time number correct0.60.91.20.81.01.1-1.1-0.3-1.0-1.11.0
Reaction time mean minus median2.43.26.42.21.91.8-1.82.5-2.00.1-0.3
Reaction time mean minus median AUC1.82.33.81.71.81.8-1.71.4-2.0-0.60.5
Reaction time num false alarms0.81.15.9-0.40.10.1-0.2-2.40.3-1.11.2
Reaction time num false alarms AUC0.71.03.70.30.80.8-0.8-1.9-0.3-1.11.1
Reaction time trials correct on left0.60.91.20.81.01.1-1.1-0.3-1.0-1.11.0
Reaction time trials on left0.81.21.60.91.21.2-1.2-0.3-1.2-1.21.1
Reaction time mean0.00.10.40.00.10.1-0.10.6-0.20.1-0.1
Reaction time mean AUC0.10.10.5-0.1-0.0-0.00.00.7-0.10.2-0.2
Median of all reaction times0.10.10.2-0.4-0.4-0.40.40.20.30.2-0.2
Reaction time omissions1.31.82.91.61.61.6-1.60.7-1.7-0.50.4
Reaction time false alarm rate0.40.53.4-0.30.00.0-0.1-1.80.3-0.60.6
Reaction time premature initiation rate1.21.63.41.31.81.8-1.8-0.4-0.9-0.70.6
Reaction time premature initiations2.73.87.02.02.72.6-2.6-0.3-1.6-1.31.2
Std. dev. reaction times0.71.02.21.21.01.0-1.01.5-1.3-0.0-0.1
Reaction time trials completed0.81.21.60.91.21.2-1.2-0.3-1.2-1.21.1
Reaction time trials AUC0.50.81.10.70.91.0-1.0-0.4-0.9-1.01.0
Run reversals in cocaine runway, females0.50.51.60.50.1-0.00.1-0.20.81.2-1.3
Run reversals in cocaine runway, males1.61.64.2-0.20.60.7-0.8-1.3-1.0-2.02.0
Latency to leave start box in cocaine runway0.50.51.30.0-0.5-0.60.60.60.21.2-1.2
Latency to leave start box in cocaine runway, F0.20.20.70.0-0.3-0.30.40.50.20.8-0.8
Latency to leave start box in cocaine runway, M0.00.00.10.1-0.0-0.00.00.3-0.10.2-0.2
Std. dev. time between licks in bursts0.60.73.4-0.20.20.2-0.3-1.9-0.1-1.01.1
Total sessions with >9 infusions1.61.82.9-1.1-1.7-1.71.7-0.61.01.3-1.2
Short access day 1 total inactive lever presses2.83.15.5-1.9-2.3-2.32.3-1.21.60.8-0.6
Short access day 10 total inactive lever presses2.02.25.2-1.9-1.7-1.71.6-2.30.8-0.00.1
Short access day 1 total infusions3.94.16.7-1.6-2.5-2.62.6-0.71.62.0-1.9
Short access day 10 total infusions4.14.68.9-0.8-2.1-2.22.30.81.73.0-2.9
Short access total infusions2.32.64.0-0.9-1.8-1.91.9-0.21.22.0-1.9
Short access day 1 locomotion3.03.24.7-1.3-2.0-2.12.2-0.41.62.0-2.0
Short access day 10 total locomotion2.52.83.9-1.2-1.8-1.91.9-0.11.62.0-1.9
Short access total locomotion2.42.53.7-1.0-1.7-1.81.8-0.31.41.9-1.9
One hour access (0.3 mA shock)5.56.411.0-3.3-3.3-3.33.2-1.72.20.8-0.6
Compulsive drug intake1.92.03.71.51.91.9-1.9-0.4-1.0-0.90.8
One hour access (shock baseline)4.65.310.2-3.0-3.2-3.13.0-0.51.80.8-0.7
Social response proportion0.50.62.10.70.60.5-0.51.4-0.20.7-0.8
Social responses0.20.20.40.60.60.6-0.60.4-0.5-0.10.0
Social time0.20.30.60.70.80.7-0.70.0-0.2-0.30.2
Soleus weight2.67.717.8-4.2-3.2-3.02.9-2.82.7-0.60.8
Bone: stiffness1.82.99.92.11.21.1-0.93.1-0.71.5-1.6
Tibialis anterior weight8.529.246.46.46.86.7-6.73.7-5.6-2.52.1
Time to tail flick, vehicle, before self-admin0.30.30.70.80.30.3-0.20.80.10.7-0.7
Time to tail flick, vehicle, after self-admin0.60.71.81.30.80.7-0.60.4-0.60.8-0.8
Time to tail flick, test, before self-admin1.61.62.4-0.9-1.2-1.31.3-0.71.51.5-1.4
Time to tail flick, test, after self-admin0.00.00.00.10.20.2-0.2-0.00.1-0.20.2
Delta time to tail flick, vehicle, before/after SA0.30.20.50.70.50.4-0.40.4-0.40.5-0.6
Delta time to tail flick, test, before/after SA2.92.63.51.21.71.8-1.80.4-1.7-1.91.8
Tibia length1.33.65.41.52.02.1-2.12.3-2.0-1.41.3
Ambulatory time before self-admin0.40.42.10.60.40.5-0.41.4-0.60.1-0.2
Ambulatory time after self-admin0.50.51.9-0.2-0.6-0.60.61.40.10.8-0.8
Bone: tissue strength0.20.21.00.1-0.1-0.10.11.00.20.5-0.5
Total heroin consumption3.64.36.42.52.52.5-2.41.9-2.4-0.40.2
Bone: trabecular number1.42.25.91.2-0.1-0.20.32.4-0.22.2-2.3
Bone: trabecular spacing0.40.62.1-1.0-0.3-0.20.2-1.50.5-0.70.7
Bone: trabecular thickness1.31.52.7-0.3-1.2-1.31.30.71.21.6-1.6
Bone: trabecular tissue density1.92.76.5-2.5-1.8-1.71.6-1.51.4-0.91.0
Water consumed over 24 hours0.40.51.21.10.80.8-0.70.6-0.50.2-0.3
Number of responses in last shaping day0.70.82.7-1.0-0.9-0.90.9-1.60.3-0.20.3