Hub : Genes

Efemp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL intron excision ratio chr1_212215284_212216731 0.2 0.16 7.9e-03 0.03 0.08 0.04 0.03 7.8e-02 6.7e-03 3.7e-02 8.3e-02
2 NAcc mRNA stability Efemp2 0.04 0.03 8.1e-07 0.04 0.04 0.04 0.04 1.8e-07 1.2e-06 5.3e-07 2.7e-07
3 Brain isoform ratio XM_039108373.2 0.04 0.03 2.6e-03 0.01 0.01 0 0 1.3e-02 4.8e-02 1.5e-01 1.2e-01
4 NAcc gene expression Efemp2 0.07 0.04 4.1e-12 0.08 0.09 0.07 0.08 9.1e-12 5.8e-13 1.7e-11 6.0e-12
5 Brain intron excision ratio chr1_212214696_212214937 0.03 0.03 8.6e-03 0.04 0.02 0.01 0.04 2.0e-04 6.5e-03 1.3e-02 3.2e-04
6 RMTg intron excision ratio chr1_212211818_212212108 0.18 0.12 6.8e-03 0.05 0.01 0.03 0.02 2.0e-02 1.6e-01 7.0e-02 1.0e-01
7 RMTg intron excision ratio chr1_212211511_212212108 0.16 0.12 9.4e-03 0.07 0.06 0.07 0.07 5.1e-03 9.9e-03 4.8e-03 4.9e-03
8 Brain isoform ratio XM_063286847.1 0.03 0.02 6.2e-03 0.02 0.01 0 0.01 1.0e-02 2.6e-02 2.2e-01 2.1e-02
9 NAcc isoform ratio XM_006230744.5 0.02 0.01 5.7e-03 0.01 0.01 0.01 0.01 1.8e-02 8.3e-03 3.4e-02 1.0e-02
10 Brain intron excision ratio chr1_212215053_212215165 0.03 0.02 3.7e-03 0.01 0.02 0.01 0.01 3.7e-02 6.5e-03 1.6e-02 1.9e-02
11 LHb intron excision ratio chr1_212216747_212216959 0.54 0.19 3.3e-04 0.12 0.14 0.12 0.11 9.0e-04 3.0e-04 8.7e-04 1.3e-03
12 NAcc alternative TSS XM_006230744.5 0.02 0.01 5.3e-03 0.01 0.01 0 0.01 4.6e-03 1.4e-02 5.7e-02 1.2e-02
13 RMTg mRNA stability Efemp2 0.11 0.08 6.1e-03 0.06 0.04 0.02 0.04 1.2e-02 3.6e-02 9.6e-02 4.1e-02
14 Adipose gene expression Efemp2 0.12 0.08 7.3e-06 0.04 0.04 0.04 0.03 1.7e-05 8.1e-05 9.1e-05 9.3e-05
15 Eye intron excision ratio chr1_212213350_212214574 0.6 0.17 9.1e-03 -0.01 0 -0.01 0.01 4.1e-01 3.2e-01 6.4e-01 2.2e-01
16 PL gene expression Efemp2 0.05 0.03 4.9e-05 0.04 0.04 0.04 0.04 4.3e-05 2.9e-05 8.6e-05 3.1e-05
17 IC intron excision ratio chr1_212211511_212212108 0.14 0.09 9.4e-04 0.08 0.06 0.07 0.07 4.4e-04 1.4e-03 9.4e-04 6.7e-04
18 IC intron excision ratio chr1_212211818_212212108 0.13 0.09 1.1e-03 0.06 0.06 0.06 0.07 2.5e-03 1.7e-03 1.1e-03 7.6e-04
19 IC isoform ratio XM_006230743.3 0.09 0.06 3.7e-03 0.02 0.05 0.03 0.03 4.6e-02 3.1e-03 1.4e-02 1.9e-02
20 IC alternative TSS XM_006230743.3 0.1 0.07 2.2e-03 0.02 0.04 0 0.02 6.2e-02 5.8e-03 2.5e-01 5.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.01.87.0-1.1-0.60.9-0.4-0.70.7-0.7-0.6-0.20.2-1.31.30.40.70.72.2-2.6-2.62.02.1
Area under the delay curve0.40.62.50.00.1-0.10.4-0.30.3-0.3-0.2-0.60.6-0.30.80.21.31.61.2-1.1-1.11.21.2
BMI with tail2.38.023.4-3.6-2.22.3-1.3-2.32.3-2.3-2.10.30.0-4.31.31.71.40.54.8-4.2-4.03.84.2
BMI without tail0.73.89.7-2.1-1.61.5-1.0-2.12.1-2.1-1.70.4-0.2-2.20.30.61.01.23.1-3.1-3.12.42.6
Body weight1.98.216.7-4.1-3.73.7-3.2-3.83.8-3.8-3.62.6-2.3-3.3-1.5-0.8-1.2-0.92.9-2.6-2.31.31.8
Weight adjusted by age0.61.84.2-1.4-1.51.3-1.6-2.02.0-1.7-1.31.5-1.5-0.8-1.4-0.9-1.5-1.6-0.1-0.1-0.0-0.7-0.6
Bone surface2.54.910.8-3.3-2.93.1-2.5-2.22.2-2.2-2.21.7-1.7-2.80.2-0.8-1.3-1.62.4-2.8-2.61.31.7
Bone volume1.12.25.7-2.2-1.61.8-1.2-1.01.0-1.0-0.90.5-0.5-2.40.90.1-0.2-1.02.1-2.3-2.21.61.8
Breakpoint value in progressive ratio session1.32.45.6-2.4-2.02.0-1.9-1.71.7-1.6-1.61.7-1.5-1.9-1.1-1.1-1.4-1.70.9-1.1-0.90.00.3
Number of licking bursts0.10.20.6-0.8-0.60.6-0.6-0.50.5-0.5-0.40.5-0.5-0.8-0.4-0.1-0.4-0.70.3-0.3-0.30.00.1
Context. condit. distance diff. score1.31.63.01.51.7-1.71.71.5-1.51.51.3-1.51.50.91.11.01.61.4-0.20.40.30.50.3
Locomotion velocity, session 10.20.20.60.3-0.10.1-0.3-0.40.4-0.4-0.50.4-0.40.8-0.7-0.5-0.20.3-0.50.60.6-0.6-0.6
Locomotion distance, session 10.81.02.8-0.9-0.70.7-0.5-1.01.0-1.0-1.00.2-0.1-0.80.50.40.50.81.7-1.6-1.61.31.5
Locomotion velocity, session 21.82.24.5-2.1-1.92.0-1.7-2.02.0-2.0-1.81.4-1.2-1.7-0.8-0.4-0.5-0.71.4-1.1-1.00.60.8
Locomotion distance, session 20.81.12.4-1.1-1.11.0-0.8-1.41.4-1.4-1.30.5-0.4-0.9-0.10.30.20.51.6-1.4-1.41.11.3
Locomotion velocity, session 30.40.51.40.00.5-0.50.60.2-0.20.20.2-0.70.8-0.50.70.91.20.91.0-0.6-0.71.11.0
Locomotion distance, session 30.00.00.10.10.2-0.20.1-0.00.0-0.10.0-0.10.10.10.10.10.20.30.0-0.0-0.10.10.0
Stereotopy head waving bouts, day 30.91.02.90.70.8-0.91.10.6-0.60.60.4-1.21.20.21.11.61.41.70.9-0.7-0.81.21.2
Stereotopy head waving duration, day 30.81.01.80.90.9-0.91.21.1-1.11.10.7-1.31.30.31.31.31.11.20.6-0.6-0.71.00.9
Locomotion velocity, session 71.21.33.4-0.20.7-0.60.90.3-0.30.30.6-1.21.3-1.31.11.81.80.91.6-1.1-1.11.81.7
Locomotion distance, session 70.30.41.3-0.20.2-0.10.2-0.60.6-0.6-0.3-0.30.4-0.40.20.41.01.21.0-0.8-0.80.91.0
Stereotopy head waving bouts, day 70.50.51.8-0.20.2-0.20.50.7-0.70.80.6-0.70.7-1.01.31.10.5-0.30.7-0.7-0.71.00.9
Stereotopy head waving duration, day 70.60.72.4-1.2-0.90.8-0.4-0.10.1-0.2-0.40.1-0.0-1.50.90.3-0.1-0.61.3-1.3-1.31.11.1
Locomotion velocity, session 80.91.12.1-0.6-1.01.1-1.4-1.41.4-1.4-1.41.4-1.50.6-1.1-1.3-1.1-0.1-0.3-0.1-0.0-0.8-0.6
Locomotion distance, session 80.40.51.70.20.5-0.60.80.5-0.50.50.4-0.81.0-0.50.81.31.20.70.8-0.3-0.31.00.9
Degree of sensitization distance0.40.41.1-0.2-0.00.10.1-0.40.4-0.4-0.2-0.30.4-0.50.40.70.70.91.1-0.9-1.01.01.0
Degree of sensitization stereotypy0.40.42.6-1.1-0.60.6-0.30.1-0.10.1-0.10.1-0.0-1.60.60.3-0.2-1.10.8-0.6-0.50.60.6
Conditioned locomotion1.31.53.2-1.4-1.61.4-1.5-1.81.8-1.8-1.61.5-1.4-0.7-1.7-1.1-1.0-0.60.2-0.1-0.0-0.5-0.3
Cocaine response after cond. corrected0.60.92.11.41.3-1.41.20.9-0.90.90.7-1.01.01.10.40.41.11.3-0.40.70.60.0-0.1
Cocaine response after cond. not corrected0.50.71.61.21.2-1.31.00.9-0.90.90.6-0.80.80.90.50.40.91.1-0.40.50.40.0-0.1
Cocaine response before conditioning0.40.51.6-1.1-0.81.0-0.9-0.50.5-0.5-0.40.7-0.7-1.0-0.0-0.1-0.9-1.30.3-0.5-0.4-0.00.1
Saline control response2.63.67.2-2.0-2.52.4-2.6-2.62.6-2.6-2.72.3-2.3-0.6-1.3-1.2-1.8-0.70.8-1.3-1.1-0.30.1
Bone: connectivity density2.03.19.1-2.1-1.82.0-1.6-1.81.8-1.8-1.60.9-0.9-1.80.7-0.4-0.20.12.4-3.0-2.91.71.9
Bone: cortical apparent density0.10.20.7-0.3-0.30.3-0.4-0.30.3-0.3-0.30.5-0.5-0.0-0.8-0.5-0.5-0.4-0.40.60.6-0.6-0.6
Bone: cortical area0.50.92.1-1.4-1.01.1-1.1-0.90.9-0.9-0.71.1-1.0-1.2-1.0-0.8-1.0-1.40.00.20.3-0.5-0.4
Bone: cortical porosity0.30.31.2-0.4-0.50.5-0.3-0.40.4-0.4-0.40.0-0.0-0.30.3-0.10.20.50.9-1.1-1.10.70.8
Bone: cortical porosity0.50.51.3-0.7-0.90.9-0.6-0.80.8-0.8-0.80.4-0.4-0.5-0.0-0.4-0.10.30.9-1.1-1.10.70.8
Bone: cortical thickness3.05.09.8-2.1-2.12.2-2.7-2.72.7-2.7-2.42.9-2.8-0.6-3.1-2.9-2.4-1.8-0.80.81.0-2.0-1.7
Bone: cortical thickness1.21.54.1-0.4-0.60.8-1.2-1.61.6-1.7-1.21.4-1.40.7-2.0-2.0-1.0-0.1-0.70.40.5-1.2-1.1
Bone: cortical tissue density0.20.31.0-0.4-0.50.5-0.6-0.50.5-0.5-0.50.7-0.70.0-1.0-0.7-0.7-0.4-0.40.60.6-0.7-0.6
Condit. Reinf. active minus inactive responses0.20.20.5-0.7-0.40.2-0.3-0.50.5-0.6-0.50.2-0.1-0.7-0.20.30.1-0.00.7-0.6-0.60.50.6
Condit. Reinf. active-inactive response ratio0.00.00.1-0.2-0.1-0.1-0.1-0.10.1-0.1-0.20.1-0.0-0.2-0.1-0.20.00.00.2-0.3-0.30.20.2
Condit. Reinf. active responses0.20.31.5-0.7-0.2-0.1-0.0-0.40.4-0.4-0.0-0.10.3-1.2-0.10.80.5-0.30.8-0.4-0.40.70.7
Condit. Reinf. inactive responses0.30.31.5-0.40.2-0.30.40.1-0.10.10.5-0.50.7-1.10.31.20.8-0.20.7-0.2-0.20.80.7
Incentive salience index mean0.40.51.8-1.1-0.60.4-0.4-0.70.7-0.7-0.60.2-0.0-1.4-0.10.60.4-0.11.2-0.9-0.80.91.0
Condit. Reinf. lever presses0.40.63.3-1.4-0.80.8-0.5-0.60.6-0.6-0.40.4-0.2-1.8-0.30.5-0.0-1.01.0-0.2-0.20.60.6
Condit. Reinf. active minus inactive responses0.20.41.60.00.2-0.10.40.9-0.90.90.7-0.60.5-0.31.30.90.0-0.40.3-0.5-0.50.50.4
Condit. Reinf. active-inactive response ratio0.71.13.30.30.9-0.71.11.6-1.61.61.5-1.21.2-0.71.51.80.6-0.70.20.10.10.70.5
Condit. Reinf. active responses0.30.52.2-0.4-0.30.5-0.20.1-0.10.20.0-0.20.1-0.51.30.6-0.00.00.9-1.5-1.51.01.0
Condit. Reinf. inactive responses0.71.03.9-0.5-0.80.8-0.8-1.01.0-1.0-1.00.4-0.50.10.5-0.5-0.11.01.2-2.0-2.00.91.1
Condit. Reinf. lever presses1.11.64.0-2.0-1.71.8-1.5-1.11.1-1.1-1.01.1-1.1-1.7-0.1-0.3-1.2-1.51.0-1.3-1.20.40.5
Condit. Reinf. lever reinforcers received0.40.52.2-0.7-0.70.8-0.5-0.10.1-0.1-0.20.1-0.2-0.61.00.3-0.4-0.30.9-1.5-1.50.80.8
Conditioned reinforcement - actives0.10.42.9-0.1-0.20.0-0.00.7-0.70.50.60.1-0.2-0.30.10.2-0.9-1.7-0.80.50.5-0.7-0.7
Conditioned reinforcement - inactives1.02.76.81.92.1-2.12.02.2-2.22.32.6-1.91.70.81.71.20.7-0.7-1.10.90.8-0.1-0.5
Conditioned locomotion4.56.712.93.33.3-3.33.23.6-3.63.43.5-2.82.72.01.92.01.60.7-1.82.01.7-0.3-0.8
Patch foraging indifference point 0 sec0.00.10.20.10.3-0.20.20.3-0.30.30.3-0.30.3-0.10.5-0.10.10.30.3-0.5-0.50.40.4
Patch foraging indifference point AUC0.82.04.0-1.9-1.82.0-1.8-1.31.3-1.2-1.21.7-1.7-1.2-1.2-1.8-1.7-2.00.10.10.2-0.7-0.5
Delay disc. indifference point, 0s delay1.01.25.80.60.4-0.41.00.0-0.0-0.00.1-1.11.20.00.90.91.92.41.3-0.8-1.01.51.5
Delay disc. indifference point, 16s delay0.60.81.80.50.9-0.91.11.0-1.01.00.9-1.21.3-0.31.30.81.20.50.6-0.4-0.41.00.8
Delay disc. indifference point, 2s delay0.30.30.80.20.4-0.30.60.4-0.40.40.4-0.70.7-0.30.60.80.90.70.5-0.4-0.40.70.7
Delay disc. indifference point, 24s delay0.10.10.70.50.1-0.20.0-0.40.4-0.4-0.20.1-0.10.8-0.5-0.40.20.9-0.30.10.1-0.3-0.3
Delay disc. indifference point, 4s delay0.60.63.60.40.3-0.20.4-0.30.3-0.3-0.3-0.60.60.30.60.31.31.90.9-0.9-1.01.01.0
Delay disc. indifference point, 8s delay0.30.42.80.30.0-0.00.2-0.30.3-0.3-0.4-0.40.40.30.5-0.21.01.70.8-0.9-0.90.80.8
Indifference point function ln k2.16.413.83.53.6-3.73.32.6-2.62.62.5-2.92.92.41.42.42.83.0-1.01.31.10.3-0.0
Indifference point function log k2.16.413.83.53.6-3.73.32.6-2.62.62.5-2.92.92.41.42.42.83.0-1.01.31.10.3-0.0
Patch foraging total patch changes 0 sec0.00.00.30.20.2-0.1-0.1-0.10.1-0.1-0.00.1-0.10.4-0.2-0.5-0.20.3-0.2-0.0-0.1-0.2-0.1
Patch foraging total patch changes 12 sec2.73.67.2-2.7-2.52.6-2.5-2.22.2-2.2-2.32.1-2.0-1.8-1.0-1.7-1.4-1.21.3-1.4-1.30.20.5
Patch foraging total patch changes 18 sec0.20.51.2-1.1-0.81.0-0.8-0.70.7-0.7-0.50.5-0.5-1.0-0.0-0.4-0.4-0.50.8-0.8-0.80.50.6
Patch foraging total patch changes 24 sec0.62.03.7-1.4-1.71.8-1.9-1.61.6-1.6-1.51.9-1.9-0.3-1.4-1.7-1.9-1.1-0.2-0.2-0.1-0.9-0.7
Patch foraging total patch changes 6 sec0.71.12.1-1.3-1.01.3-1.4-1.41.4-1.4-1.21.1-1.1-0.6-0.5-1.1-0.70.00.8-1.2-1.10.20.4
Patch foraging time to switch 0 sec0.72.88.0-2.4-1.61.6-1.0-1.31.3-1.3-1.10.4-0.2-2.80.60.90.5-0.82.7-2.5-2.42.02.2
Patch foraging water rate 0 sec1.34.810.03.22.6-2.62.02.3-2.32.42.2-1.31.13.1-0.1-0.10.10.8-3.02.92.8-2.0-2.3
Patch foraging water rate 12 sec2.18.422.94.83.8-3.92.92.8-2.82.82.8-2.21.94.80.40.61.12.6-3.42.92.7-1.9-2.3
Patch foraging water rate 18 sec1.12.46.82.62.1-2.31.71.3-1.31.31.4-1.21.12.50.10.60.92.0-1.61.31.1-0.8-1.0
Patch foraging water rate 24 sec2.84.09.53.12.4-2.62.12.1-2.12.11.9-1.41.32.9-0.00.60.71.4-2.42.52.3-1.4-1.7
Patch foraging water rate 6 sec2.74.011.73.22.6-2.71.81.5-1.51.51.6-1.11.03.4-0.40.00.52.0-2.62.52.4-1.7-2.0
Seeking ratio, delayed vs. immediate footshock0.40.61.4-0.00.4-0.40.5-0.30.3-0.30.1-0.80.8-0.60.80.91.00.71.1-1.0-1.01.21.2
Distance traveled before self-admin0.20.52.4-1.2-1.00.9-0.5-0.00.0-0.1-0.40.2-0.2-1.50.40.1-0.1-0.91.0-0.8-0.70.80.8
Distance traveled after self-admin0.10.21.1-0.6-0.60.5-0.50.2-0.20.1-0.30.4-0.4-0.50.1-0.9-0.6-1.00.2-0.1-0.1-0.00.0
Extensor digitorum longus weight4.919.737.9-6.2-6.05.8-5.5-5.85.8-5.8-5.55.1-4.7-4.4-4.2-2.9-3.4-3.32.3-1.6-1.2-0.40.3
Bone: elastic displacement1.11.44.11.41.0-1.00.30.2-0.20.20.40.2-0.22.0-1.2-0.7-0.30.6-1.91.91.8-1.7-1.8
Bone: elastic work1.41.84.4-0.8-1.11.1-1.5-1.81.8-1.8-1.61.7-1.70.3-2.1-1.6-1.2-0.2-0.60.70.8-1.3-1.1
Bone: endosteal estimation1.12.66.30.71.1-1.21.71.4-1.41.51.4-2.02.0-0.72.22.52.01.21.4-1.1-1.22.01.9
Bone: endosteal perimeter1.43.58.70.71.4-1.42.02.1-2.12.12.0-2.32.3-0.92.92.72.00.71.4-1.2-1.32.22.0
Epididymis fat weight1.68.218.13.13.3-3.33.74.3-4.34.33.8-3.33.31.32.63.02.30.9-1.21.61.30.4-0.0
Delta time in closed arm before/after self-admin0.70.61.90.0-0.30.3-0.7-1.31.3-1.4-1.10.7-0.70.8-1.0-0.8-0.21.20.1-0.4-0.4-0.2-0.1
Delta time in open arm before/after self-admin0.30.32.8-0.7-0.50.4-0.30.5-0.50.50.30.2-0.2-0.90.1-0.3-0.7-1.7-0.20.20.2-0.2-0.3
Diff in mean of infusions in LGA sessions0.30.51.2-0.8-0.80.8-1.0-0.50.5-0.5-0.81.0-1.0-0.2-0.8-0.9-1.0-1.1-0.20.00.1-0.5-0.4
Delay discount exponential model param0.30.51.9-0.0-0.0-0.0-0.30.4-0.40.40.20.4-0.50.2-0.5-0.0-1.0-1.4-1.01.01.0-1.0-1.0
Extinction: sum of active levers before priming1.31.94.9-2.2-1.61.6-1.4-1.51.5-1.4-1.41.1-0.9-2.2-0.3-0.3-0.5-1.11.6-1.6-1.50.91.1
Active lever presses in extinction session 62.12.15.1-2.0-2.12.0-1.8-1.41.4-1.3-1.41.7-1.6-1.6-1.3-0.7-1.7-2.30.2-0.20.0-0.5-0.4
Bone: final force1.42.34.9-2.2-2.22.1-1.9-1.91.9-1.9-1.81.7-1.6-1.7-1.0-0.9-1.3-1.40.9-0.9-0.70.00.3
Bone: final moment1.32.24.4-2.1-2.12.0-1.8-1.81.8-1.8-1.71.6-1.5-1.5-1.0-0.9-1.2-1.20.9-0.9-0.70.00.3
Food consumed during 24 hour testing period0.20.41.60.0-0.30.2-0.30.3-0.30.30.10.5-0.50.3-0.4-0.6-0.9-1.3-1.00.90.9-1.0-1.1
Glucose2.64.18.11.62.1-2.22.41.9-1.91.91.7-2.62.60.32.62.32.82.11.3-0.8-0.82.22.0
Heart weight2.03.310.61.11.2-1.31.60.7-0.70.70.6-1.92.00.22.31.82.73.31.8-2.0-2.12.42.3
Delay discount hyperbolic model param0.40.51.9-0.0-0.1-0.0-0.30.3-0.30.30.20.5-0.50.3-0.6-0.2-1.1-1.4-1.01.01.0-1.1-1.1
Intermittent access intake day 1-15 change0.21.33.21.21.3-1.31.31.4-1.41.51.8-1.01.00.60.60.90.2-0.9-1.21.31.3-0.6-0.8
Intermittent access intake escalation0.21.32.91.11.2-1.11.11.4-1.41.51.7-0.80.80.50.40.8-0.1-1.3-1.31.41.4-0.8-1.0
Intermittent access intake escalation 20.81.43.31.01.0-1.01.11.7-1.71.81.6-0.80.80.40.40.7-0.0-1.2-1.31.61.5-0.7-0.9
Intermitt. access day 1 inactive lever presses0.00.20.90.30.5-0.50.40.9-0.90.70.6-0.30.40.00.2-0.20.1-0.4-0.30.60.6-0.1-0.2
Intermitt. access day 15 inactive lever presses0.31.84.21.11.7-1.61.71.9-1.91.82.0-1.71.7-0.01.51.61.2-0.5-0.30.50.40.50.2
Intermitt. access escalation Index0.92.85.42.02.1-2.02.21.6-1.61.81.8-2.12.11.11.71.62.22.30.10.30.11.00.7
Intermittent access day 1 total infusions1.64.810.71.31.9-1.92.42.1-2.11.92.1-2.82.8-0.33.32.82.81.71.5-1.6-1.82.42.2
Intermittent access day 15 total infusions2.15.211.12.32.8-2.82.93.0-3.03.03.3-2.92.80.62.72.82.00.1-0.50.40.20.80.4
Intermittent access terminal intake (last 3 days)2.95.19.61.92.4-2.52.83.1-3.13.03.1-2.92.80.22.93.02.10.2-0.10.0-0.21.20.8
Intermittent access total infusions3.54.28.01.62.2-2.12.42.3-2.32.22.6-2.72.6-0.02.82.82.30.80.6-0.9-1.11.71.3
Intermittent access day 1 locomotion1.63.06.41.21.7-1.62.01.7-1.71.61.8-2.32.3-0.12.52.22.21.41.0-1.0-1.21.81.6
Intermittent access day 15 total locomotion1.14.49.91.92.6-2.52.72.5-2.52.63.1-2.82.70.12.82.61.9-0.2-0.20.1-0.01.10.7
Intermittent access total locomotion6.07.213.42.13.0-2.93.43.2-3.23.13.6-3.63.6-0.23.73.52.90.50.5-0.3-0.62.01.5
Intermittent access standard deviation0.21.22.81.51.4-1.41.31.5-1.51.41.7-1.11.01.10.50.50.40.0-1.10.80.7-0.5-0.7
Left kidney weight0.32.54.81.31.6-1.62.22.0-2.02.02.0-2.02.2-0.21.51.82.10.70.20.70.51.00.7
Right kidney weight0.21.12.31.11.1-1.11.31.5-1.51.51.4-1.01.10.40.40.90.80.1-0.81.41.3-0.2-0.4
Cocaine induced anxiety0.00.10.9-0.3-0.20.0-0.0-0.10.10.10.10.00.0-0.50.10.2-0.2-0.90.00.10.10.0-0.0
Post-drug Anxiety0.40.51.5-1.1-1.00.9-0.9-0.60.6-0.5-0.70.8-0.8-0.9-0.4-0.2-0.8-1.20.2-0.00.1-0.2-0.1
Baseline Anxiety0.20.41.0-0.4-0.70.8-0.8-0.40.4-0.5-0.90.9-0.90.3-0.7-1.0-0.70.3-0.20.20.2-0.5-0.4
Tail length0.42.45.3-0.7-1.61.5-1.7-1.81.8-1.8-1.72.0-2.00.7-2.3-2.0-1.7-0.4-0.90.70.8-1.6-1.4
Length with tail1.56.911.5-2.5-3.23.1-3.3-3.33.3-3.3-3.33.4-3.3-0.6-3.3-2.7-2.8-1.3-0.30.40.6-1.7-1.3
Length without tail1.15.69.7-2.0-2.72.7-3.0-2.92.9-2.9-3.13.1-3.1-0.1-2.8-2.8-2.7-1.0-0.40.30.6-1.7-1.3
Times rat made contact with spout0.50.61.3-0.6-0.80.7-0.7-1.11.1-1.1-1.00.6-0.6-0.0-0.4-0.9-0.10.30.7-1.0-1.00.30.5
Lifetime Intake2.53.16.31.41.9-1.82.11.9-1.91.82.1-2.32.20.12.52.42.11.10.7-1.0-1.21.61.3
Liver weight, left0.50.82.01.41.2-1.31.10.7-0.70.70.8-0.80.71.2-0.10.60.61.1-0.81.21.1-0.4-0.5
Liver weight, right1.22.15.72.42.1-2.11.71.1-1.11.11.2-1.51.42.20.51.11.52.2-0.80.90.8-0.1-0.2
Locomotor activity1.21.97.12.41.9-1.91.20.8-0.80.81.1-0.70.62.7-0.5-0.40.41.6-1.81.51.4-1.2-1.3
Locomotor testing distance1.02.611.02.82.1-2.01.30.9-0.90.91.1-0.80.63.3-0.4-0.40.62.2-2.01.61.4-1.3-1.4
Locomotor testing rearing0.72.511.02.92.1-2.11.51.2-1.21.21.1-1.31.03.30.8-0.50.92.5-1.30.50.4-0.4-0.6
Locomotion in novel chamber3.44.58.12.62.6-2.62.72.8-2.82.92.8-2.52.41.41.92.21.90.8-0.91.61.20.3-0.0
Locomotion in novel chamber post-restriction1.03.06.61.92.1-2.12.22.6-2.62.52.4-2.12.00.71.61.61.50.6-0.61.00.80.40.1
Fecal boli incidents, locomotor time 10.10.32.0-0.50.00.20.20.7-0.70.70.7-0.20.2-1.10.30.7-0.3-1.4-0.20.50.6-0.1-0.2
Change in fecal boli incidents, locomotor task0.40.41.90.2-0.1-0.1-0.1-0.70.7-0.8-0.7-0.0-0.00.5-0.10.20.41.40.6-1.1-1.10.50.6
Time >=10cm from walls, locomotor time 11.72.17.80.10.9-0.71.41.0-1.00.91.5-1.71.8-1.42.52.81.40.41.3-1.2-1.31.81.6
Bouts of movement, locomotor time 11.11.55.1-1.3-1.71.4-1.4-1.01.0-1.1-1.51.4-1.4-0.8-0.6-2.3-1.5-1.5-0.00.10.1-0.6-0.4
Total resting periods, locomotor time 10.70.82.8-1.2-1.31.2-1.0-0.70.7-0.7-1.01.0-1.0-0.9-0.3-1.7-1.2-1.40.1-0.00.0-0.3-0.2
Rest time, locomotor task time 10.81.22.71.41.1-1.21.31.6-1.61.71.3-1.01.00.90.60.40.50.1-1.01.41.3-0.4-0.6
Distance moved, locomotor task time 10.30.72.8-0.6-0.10.3-0.1-0.60.6-0.6-0.2-0.20.3-0.80.70.80.80.81.3-1.7-1.61.21.3
Vertical activity count, locomotor time 10.10.61.61.01.3-1.21.00.5-0.50.50.9-0.90.90.60.50.80.90.7-0.2-0.2-0.20.20.1
Time >=10cm from walls, locomotor time 20.00.10.9-0.5-0.30.30.10.3-0.30.30.3-0.10.2-1.00.30.2-0.1-0.50.20.00.00.20.2
Bouts of movement, locomotor time 20.10.41.4-0.8-0.80.7-0.7-0.70.7-0.7-0.80.5-0.5-0.7-0.3-1.2-0.5-0.60.5-0.5-0.50.20.3
Total resting periods, locomotor time 20.10.20.6-0.6-0.50.5-0.3-0.30.3-0.3-0.50.2-0.2-0.70.1-0.8-0.2-0.40.6-0.5-0.50.40.5
Rest time, locomotor task time 21.11.83.41.61.5-1.61.81.7-1.71.71.5-1.71.70.71.41.01.51.1-0.40.80.60.40.2
Distance moved, locomotor task time 20.81.11.9-1.1-1.21.2-1.4-1.31.3-1.3-1.21.4-1.3-0.4-1.0-1.1-0.9-0.70.0-0.5-0.3-0.6-0.4
Vertical activity count, locomotor time 20.40.92.60.40.1-0.1-0.6-0.60.6-0.7-0.40.9-0.91.3-1.6-0.9-1.0-0.3-1.40.80.9-1.6-1.6
Light reinforcement 10.00.10.90.70.5-0.20.20.1-0.10.10.4-0.10.00.90.1-0.3-0.10.5-0.50.10.1-0.3-0.3
Light reinforcement 20.41.02.90.81.1-1.01.11.4-1.41.51.7-1.00.90.00.51.20.3-0.7-0.70.80.8-0.2-0.4
Bone: marrow area1.22.86.90.71.2-1.31.81.5-1.51.51.5-2.12.1-0.72.32.62.11.41.5-1.1-1.22.12.0
Bone: maximum diameter0.10.32.3-0.7-0.50.5-0.30.3-0.30.30.10.3-0.3-1.00.00.1-0.7-1.5-0.10.30.3-0.2-0.2
Bone: maximum force1.73.49.3-3.0-2.52.5-2.0-1.91.9-1.9-1.91.5-1.3-2.9-0.4-0.2-0.9-1.52.0-1.8-1.61.01.3
Bone: maximum moment1.73.18.4-2.9-2.42.3-1.9-1.91.9-1.9-1.81.5-1.3-2.7-0.4-0.2-0.8-1.41.9-1.7-1.61.01.2
Mean time between licks in bursts0.10.61.8-0.0-0.50.6-0.9-1.11.1-1.1-1.40.9-1.01.0-1.0-0.9-0.60.8-0.2-0.1-0.1-0.6-0.4
Mean num. licks in bursts0.10.20.90.80.5-0.50.40.1-0.10.20.1-0.50.40.90.5-0.30.60.90.1-0.3-0.30.30.3
Cd content in liver1.01.22.81.01.2-1.21.31.6-1.61.61.7-1.31.30.11.11.10.6-0.5-0.30.30.30.30.1
Co content in liver1.31.54.91.81.2-1.20.70.6-0.60.60.6-0.20.12.2-0.9-0.90.10.9-1.81.91.9-1.5-1.6
Cu content in liver0.20.30.7-0.30.3-0.20.2-0.10.1-0.10.2-0.40.5-0.80.40.30.70.40.8-0.8-0.80.80.8
Fe content in liver0.20.30.7-0.2-0.30.4-0.6-0.60.6-0.6-0.40.7-0.70.4-0.9-0.5-0.8-0.2-0.50.30.3-0.7-0.7
K content in liver0.50.51.1-0.8-0.50.6-0.5-0.90.9-0.9-0.80.3-0.2-0.8-0.1-0.20.20.41.1-1.0-0.90.70.8
Mg content in liver0.40.52.00.50.7-0.70.70.3-0.30.30.2-0.70.80.30.60.61.01.40.5-0.6-0.60.80.7
Mn content in liver1.92.14.8-2.2-2.12.1-2.0-1.41.4-1.4-1.61.8-1.7-1.6-1.0-0.5-1.7-1.80.4-0.6-0.4-0.4-0.2
Na content in liver0.70.81.6-0.5-0.60.7-0.9-0.40.4-0.4-0.51.1-1.0-0.0-1.2-1.3-1.2-1.0-0.91.01.1-1.2-1.1
Rb content in liver1.31.64.41.71.8-1.61.51.0-1.01.01.1-1.51.41.41.30.31.42.10.1-0.5-0.60.80.6
Se content in liver0.20.30.70.20.5-0.40.40.7-0.70.80.9-0.60.5-0.20.80.80.1-0.4-0.1-0.2-0.20.20.1
Sr content in liver2.11.93.2-1.4-1.71.7-1.7-1.21.2-1.3-1.41.8-1.8-0.5-1.6-1.6-1.6-1.7-0.50.40.6-1.1-1.0
Zn content in liver0.20.20.5-0.6-0.40.5-0.5-0.70.7-0.7-0.70.4-0.3-0.5-0.4-0.50.10.10.6-0.5-0.50.30.4
Bone: minimum diameter1.63.06.10.31.1-1.21.61.2-1.21.21.4-2.02.1-1.12.42.22.31.21.9-1.6-1.72.52.4
Time in familiar zone, hab. session 10.40.41.90.20.6-0.50.70.6-0.60.60.6-0.70.8-0.40.81.40.80.40.5-0.3-0.40.70.7
Time in novel zone, hab. session 10.40.52.71.00.3-0.40.0-0.00.00.0-0.20.2-0.31.6-0.6-1.2-0.30.7-1.00.60.6-0.9-0.9
Total zone transitions, hab. session 10.50.71.7-1.3-1.01.0-0.9-1.11.1-1.1-0.80.7-0.6-1.3-0.40.0-0.2-0.70.9-0.6-0.60.40.5
Total locomotion distance, hab. session 10.40.51.30.10.5-0.60.90.7-0.70.70.6-0.91.0-0.70.71.11.10.30.70.10.00.90.8
Locomotion velocity, hab. session 10.20.20.8-0.30.1-0.10.40.1-0.10.10.1-0.40.6-0.90.30.70.70.00.8-0.2-0.20.80.7
Time in familiar zone, hab. session 20.30.41.60.50.3-0.1-0.3-0.50.5-0.5-0.50.5-0.61.3-0.8-0.8-0.40.6-0.70.40.4-0.8-0.8
Time in novel zone, hab. session 20.30.40.9-0.5-0.40.30.10.1-0.10.10.1-0.30.4-0.90.70.60.4-0.01.0-0.9-0.91.01.0
Total zone transitions, hab. session 22.12.78.7-1.5-1.51.4-0.9-1.31.3-1.3-1.40.2-0.1-1.51.20.70.60.82.7-3.0-2.92.22.5
Total locomotion distance, hab. session 21.01.43.9-0.3-0.1-0.00.5-0.10.1-0.1-0.2-0.80.9-0.91.31.41.41.31.9-1.7-1.71.92.0
Locomotion velocity, hab. session 21.11.53.9-0.20.1-0.20.70.2-0.20.20.1-1.01.1-1.01.51.71.51.11.9-1.6-1.62.02.0
Novel to familiar place preference ratio0.50.73.0-1.5-1.21.1-0.7-0.00.0-0.0-0.30.5-0.4-1.70.30.2-0.6-1.60.8-0.6-0.50.50.5
Novelty place preference0.30.41.9-1.0-0.80.7-0.30.3-0.30.30.00.1-0.1-1.40.60.3-0.3-1.20.7-0.5-0.50.60.6
Time in novel zone, NPP test0.20.31.2-0.8-0.70.6-0.30.3-0.30.3-0.00.1-0.1-1.10.60.3-0.2-0.90.6-0.6-0.50.50.5
Total zone transitions, NPP test1.52.34.4-2.1-2.12.0-1.6-1.81.8-1.8-1.71.2-1.1-1.7-0.3-0.4-0.5-0.61.7-1.7-1.60.91.2
Total locomotion distance, NPP test0.30.41.6-0.6-0.40.30.0-0.50.5-0.5-0.3-0.20.3-0.90.20.60.80.41.3-0.8-0.81.11.1
Locomotion velocity, NPP test0.30.41.5-0.7-0.40.3-0.0-0.50.5-0.5-0.3-0.10.3-1.10.20.50.70.21.2-0.7-0.71.01.1
Intraocular pressure1.11.73.51.31.2-1.21.11.8-1.81.81.9-0.80.70.90.40.1-0.4-1.3-1.71.71.7-1.1-1.3
Delta distance traveled before/after self-admin0.30.31.70.70.4-0.4-0.00.2-0.20.1-0.10.2-0.31.3-0.4-0.9-0.40.3-0.90.60.6-0.8-0.8
Delta ambulatory time before/after self-admin0.20.31.50.60.2-0.2-0.3-0.10.1-0.2-0.30.4-0.51.2-0.5-0.9-0.50.2-0.80.40.4-0.8-0.8
Parametrial fat weight2.96.812.02.43.0-3.03.53.4-3.43.43.2-3.43.40.42.93.12.91.50.10.60.41.51.1
Pavlov. Cond. lever latency0.20.31.00.90.7-0.60.40.5-0.50.50.5-0.20.11.00.0-0.5-0.10.2-0.80.40.4-0.5-0.6
Pavlov. Cond. magazine entry latency0.60.72.8-1.1-0.70.5-0.0-0.00.0-0.0-0.3-0.20.4-1.70.70.80.5-0.21.5-1.0-1.01.31.4
Pavlov. Cond. change in total contacts0.50.53.6-1.0-0.40.30.20.5-0.50.50.3-0.30.5-1.90.70.90.3-1.10.9-0.2-0.20.80.8
Pavlov. Cond. index score0.20.21.3-0.8-0.70.5-0.3-0.00.0-0.0-0.30.2-0.1-1.10.10.3-0.1-0.70.5-0.00.00.30.3
Pavlov. Cond. latency score0.10.21.0-0.7-0.60.4-0.10.0-0.00.0-0.30.00.1-1.00.30.60.2-0.30.7-0.2-0.20.50.6
Pavlov. Cond. lever contacts0.20.20.8-0.6-0.40.3-0.1-0.20.2-0.2-0.3-0.00.1-0.90.20.50.30.10.8-0.4-0.40.60.7
Pavlov. Cond. magazine entry number0.20.31.40.90.8-0.60.40.0-0.00.00.2-0.40.31.10.20.20.51.2-0.2-0.2-0.30.00.0
Pavlov. Cond. intertrial magazine entries0.30.41.20.60.8-0.80.50.6-0.60.61.1-0.40.40.40.00.0-0.0-0.5-0.80.80.8-0.5-0.6
Pavlov. Cond. lever-magazine prob. diff.0.30.42.2-1.1-0.90.7-0.4-0.10.1-0.2-0.40.2-0.1-1.50.10.3-0.1-0.80.8-0.2-0.10.50.6
Pavlov. Cond. response bias0.20.21.2-0.8-0.60.5-0.3-0.00.0-0.1-0.20.3-0.2-1.1-0.2-0.0-0.3-1.00.20.30.30.00.1
Pavlov. Cond. lever latency0.40.52.11.10.9-1.00.80.5-0.50.50.4-0.70.71.10.40.40.91.5-0.10.0-0.10.30.2
Pavlov. Cond. magazine entry latency2.43.47.6-2.8-2.42.5-2.2-2.12.1-2.1-2.01.7-1.6-2.2-0.7-1.3-1.1-1.41.7-1.8-1.70.71.0
Pavlov. Cond. change in total contacts0.61.56.2-2.2-1.61.7-1.2-0.60.6-0.6-0.60.8-0.7-2.50.3-0.1-0.9-2.11.2-1.1-1.00.70.8
Pavlov. Cond. index score1.32.05.8-2.4-1.92.0-1.6-1.41.4-1.4-1.21.3-1.1-2.3-0.4-0.6-1.1-1.81.2-1.2-1.00.50.7
Pavlov. Cond. latency score1.11.75.3-2.3-1.71.8-1.5-1.31.3-1.3-1.01.1-1.0-2.3-0.4-0.5-0.9-1.81.1-1.0-0.80.40.6
Pavlov. Cond. lever contacts0.30.51.8-1.1-0.91.0-0.8-0.50.5-0.5-0.40.7-0.7-1.0-0.2-0.4-0.9-1.40.2-0.2-0.1-0.2-0.1
Pavlov. Cond. magazine entry number4.15.312.23.53.1-3.32.92.6-2.62.62.4-2.32.22.81.01.51.82.1-1.71.91.7-0.5-0.8
Pavlov. Cond. intertrial magazine entries0.51.01.81.41.3-1.31.21.3-1.31.31.3-1.11.00.90.60.80.60.3-0.70.70.6-0.1-0.3
Pavlov. Cond. lever-magazine prob. diff.1.62.46.7-2.6-2.12.2-1.8-1.61.6-1.6-1.41.4-1.3-2.4-0.5-0.7-1.2-1.91.3-1.3-1.10.50.7
Pavlov. Cond. response bias1.21.64.2-2.1-1.71.8-1.5-1.21.2-1.2-1.21.2-1.2-1.8-0.3-0.8-1.1-1.51.0-1.1-1.00.30.5
Time in closed arm before self-admin0.40.61.40.20.5-0.50.81.2-1.21.11.1-0.90.9-0.51.21.20.7-0.20.4-0.2-0.30.70.6
Time in closed arm after self-admin0.20.20.70.40.7-0.60.50.2-0.20.10.4-0.50.50.20.20.90.50.50.10.10.10.20.2
Time in open arm before self-admin0.50.74.50.90.5-0.40.0-0.80.8-0.8-0.70.2-0.21.6-1.0-0.70.52.1-0.30.20.2-0.3-0.3
Time in open arm after self-admin0.20.21.20.1-0.40.3-0.4-0.20.2-0.1-0.60.5-0.50.6-0.6-1.1-0.30.4-0.30.10.1-0.4-0.3
Bone: periosteal estimation0.20.41.7-0.50.0-0.00.40.3-0.30.40.5-0.50.6-1.30.61.10.5-0.40.8-0.4-0.40.90.8
Bone: periosteal perimeter0.20.41.6-0.8-0.30.4-0.10.2-0.20.20.1-0.20.2-1.30.80.70.2-0.50.9-0.8-0.80.80.8
Bone: post-yield work3.66.117.5-2.3-0.80.80.40.2-0.20.20.1-1.31.6-4.22.83.02.1-0.04.1-3.5-3.54.04.0
Progressive ratio test 1 active lever presses0.20.30.80.40.5-0.60.50.7-0.70.60.8-0.70.60.10.90.30.4-0.10.0-0.6-0.60.40.3
Progressive ratio test 1 breakpoint0.10.20.70.30.4-0.50.50.6-0.60.60.8-0.60.50.00.90.30.3-0.20.0-0.6-0.60.30.2
Progressive ratio test 1 inactive lever presses0.00.10.30.30.3-0.30.30.3-0.30.20.6-0.30.30.10.5-0.40.0-0.3-0.1-0.3-0.30.10.0
Progressive ratio test 2 active lever presses1.52.15.21.41.7-1.61.82.0-2.01.92.3-1.91.80.41.91.61.1-0.0-0.3-0.2-0.30.60.3
Progressive ratio test 2 breakpoint1.62.05.11.41.7-1.61.72.0-2.01.92.3-1.81.70.41.81.61.1-0.1-0.4-0.1-0.30.50.2
Progressive ratio test 2 inactive lever presses2.37.215.23.03.4-3.33.53.3-3.33.43.9-3.53.31.13.23.02.40.8-0.60.60.31.00.5
Incentive Sensitization - Responses0.10.41.2-0.30.10.10.30.2-0.20.20.5-0.50.5-0.80.91.00.5-0.30.7-1.1-1.10.80.8
Incentive Sensitization - Breakpoint0.20.41.3-0.10.4-0.10.50.4-0.40.40.7-0.70.7-0.70.91.10.6-0.20.6-0.9-0.90.80.7
Sum of active levers in priming session hrs 5-63.02.914.1-1.1-1.01.0-1.3-0.50.5-0.4-0.01.6-1.6-0.7-1.6-1.1-2.7-3.8-1.81.92.0-2.2-2.2
Progressive ratio0.92.67.1-1.6-1.31.2-0.4-1.11.1-1.2-1.1-0.20.3-2.21.21.20.90.52.7-2.6-2.72.32.4
Food seeking constrained by brief footshock0.20.21.2-0.2-0.20.2-0.4-1.11.1-0.9-0.50.4-0.40.1-0.50.1-0.3-0.10.1-0.3-0.2-0.1-0.1
Seeking ratio, punishment vs. effort0.81.85.71.91.6-1.50.70.5-0.50.70.8-0.10.02.4-0.9-0.7-0.20.6-2.11.81.9-1.7-1.8
Retroperitoneal fat weight6.026.647.06.66.7-6.96.76.5-6.56.66.1-6.26.04.04.44.74.94.5-1.82.11.61.10.3
Reaction time number correct0.20.71.3-0.3-0.70.6-0.8-0.60.6-0.6-0.61.1-1.10.3-1.1-1.1-1.0-0.6-0.80.80.9-1.2-1.1
Reaction time mean minus median0.42.77.1-2.7-2.52.4-1.9-1.51.5-1.5-1.61.6-1.5-2.5-1.0-0.0-1.3-2.41.0-0.7-0.60.10.3
Reaction time mean minus median AUC0.21.63.5-1.8-1.81.8-1.5-1.31.3-1.3-1.21.5-1.4-1.5-1.3-0.4-1.3-1.90.20.00.2-0.5-0.4
Reaction time num false alarms0.30.51.70.80.9-0.80.3-0.30.3-0.3-0.10.00.11.0-1.0-0.40.41.3-0.61.00.9-0.6-0.6
Reaction time num false alarms AUC0.20.41.90.10.2-0.1-0.3-0.90.9-1.0-0.70.6-0.40.5-1.4-0.70.11.0-0.30.60.7-0.6-0.5
Reaction time trials correct on left0.20.71.3-0.3-0.70.6-0.8-0.60.6-0.6-0.61.1-1.10.3-1.1-1.1-1.0-0.6-0.80.80.9-1.2-1.1
Reaction time trials on left0.30.91.6-0.4-0.80.7-1.0-0.70.7-0.7-0.71.2-1.20.3-1.3-1.2-1.2-0.7-0.90.91.0-1.2-1.2
Reaction time mean0.10.10.9-0.5-0.30.40.00.2-0.20.20.2-0.10.1-0.90.20.5-0.1-0.90.3-0.0-0.00.30.2
Reaction time mean AUC0.10.21.2-0.5-0.20.30.20.4-0.40.40.3-0.30.3-1.10.30.70.1-0.90.4-0.1-0.10.50.4
Median of all reaction times0.20.30.50.10.3-0.20.60.7-0.70.70.7-0.70.7-0.50.70.70.4-0.30.2-0.1-0.10.50.4
Reaction time omissions0.91.53.7-1.9-1.81.7-1.5-1.31.3-1.3-1.51.4-1.3-1.6-1.0-0.6-1.1-1.40.6-0.2-0.1-0.10.0
Reaction time false alarm rate0.20.31.70.50.8-0.70.4-0.30.3-0.3-0.1-0.20.30.5-0.70.10.71.3-0.10.40.3-0.0-0.0
Reaction time premature initiation rate2.03.27.5-1.3-2.01.9-2.3-2.52.5-2.5-2.72.2-2.20.3-2.0-2.1-1.50.50.2-0.7-0.6-0.8-0.4
Reaction time premature initiations1.75.210.0-1.7-2.52.4-2.9-2.92.9-3.0-3.23.0-3.00.3-2.8-3.0-2.4-0.3-0.4-0.10.0-1.5-1.2
Std. dev. reaction times0.20.82.3-1.5-1.41.4-0.9-0.70.7-0.7-0.70.8-0.7-1.5-0.40.2-0.8-1.50.5-0.3-0.20.10.2
Reaction time trials completed0.30.91.6-0.4-0.80.7-1.0-0.70.7-0.7-0.71.2-1.20.3-1.3-1.2-1.2-0.7-0.90.91.0-1.2-1.2
Reaction time trials AUC0.20.61.3-0.2-0.60.5-0.8-0.60.6-0.6-0.61.0-1.00.4-1.1-1.0-1.0-0.5-0.80.80.9-1.1-1.0
Run reversals in cocaine runway, females1.21.33.0-0.8-0.30.5-0.3-1.61.6-1.5-0.90.00.1-0.9-0.00.81.01.61.7-1.7-1.61.31.4
Run reversals in cocaine runway, males1.11.24.00.90.6-0.60.10.1-0.10.20.50.4-0.41.3-1.3-0.6-0.8-0.6-1.91.92.0-1.8-1.9
Latency to leave start box in cocaine runway0.60.81.9-0.30.3-0.30.61.0-1.00.70.5-0.80.9-1.01.11.01.20.31.2-0.8-0.91.41.3
Latency to leave start box in cocaine runway, F0.40.51.2-0.20.1-0.10.40.8-0.80.50.3-0.60.7-0.70.80.21.10.51.0-0.7-0.71.11.1
Latency to leave start box in cocaine runway, M0.10.11.0-0.40.1-0.10.00.2-0.20.10.1-0.10.2-0.70.31.00.2-0.40.5-0.3-0.30.40.4
Std. dev. time between licks in bursts0.30.61.90.60.1-0.2-0.2-0.70.7-0.7-0.80.5-0.51.4-1.2-0.8-0.21.2-0.70.60.6-0.8-0.8
Total sessions with >9 infusions0.60.83.0-0.30.1-0.00.2-0.00.0-0.20.2-0.60.6-0.71.10.80.90.61.2-1.7-1.71.31.3
Short access day 1 total inactive lever presses1.02.03.51.61.9-1.81.81.8-1.81.71.6-1.71.70.81.51.61.51.2-0.20.20.10.50.3
Short access day 10 total inactive lever presses0.10.41.00.81.0-0.90.70.5-0.50.50.6-0.60.60.60.10.60.70.7-0.30.60.50.0-0.1
Short access day 1 total infusions1.22.34.21.11.4-1.41.71.8-1.81.51.4-1.91.90.02.02.12.01.50.8-0.7-0.81.51.3
Short access day 10 total infusions1.83.06.5-0.10.8-0.71.20.7-0.70.51.0-1.81.8-1.32.52.42.21.02.1-2.5-2.62.52.4
Short access total infusions1.11.63.50.30.8-0.71.00.6-0.60.40.8-1.41.4-0.51.81.91.71.31.4-1.7-1.81.71.7
Short access day 1 locomotion1.11.82.91.11.6-1.41.61.5-1.51.31.5-1.71.70.21.71.71.60.90.4-0.7-0.81.10.9
Short access day 10 total locomotion0.41.62.90.61.2-1.21.51.1-1.10.91.4-1.71.7-0.51.61.71.70.60.8-0.9-1.01.41.2
Short access total locomotion1.21.83.40.91.5-1.31.61.4-1.41.21.6-1.81.8-0.31.81.71.70.80.7-0.9-1.01.31.2
One hour access (0.3 mA shock)4.45.29.62.93.0-2.92.92.9-2.92.83.1-2.82.71.62.32.12.11.5-0.80.60.30.60.2
Compulsive drug intake2.03.08.3-0.8-1.51.5-2.0-2.42.4-2.3-2.22.2-2.20.8-2.4-2.9-1.60.4-0.50.30.4-1.3-1.0
One hour access (shock baseline)2.77.214.22.73.2-3.23.43.7-3.73.63.8-3.43.30.83.03.12.40.6-0.60.60.40.90.5
Social response proportion0.30.40.8-0.9-0.80.9-0.8-0.60.6-0.6-0.60.6-0.7-0.6-0.1-0.4-0.9-0.80.4-0.7-0.70.10.2
Social responses0.20.30.7-0.2-0.40.4-0.7-0.60.6-0.6-0.60.7-0.80.4-0.6-0.8-0.9-0.3-0.4-0.1-0.0-0.5-0.5
Social time0.30.51.4-0.2-0.80.6-0.9-0.80.8-0.8-0.90.9-1.00.6-0.9-1.2-0.9-0.3-0.50.20.2-0.7-0.7
Soleus weight2.57.314.33.63.6-3.83.63.2-3.23.23.4-3.13.12.11.42.22.51.9-1.42.01.70.1-0.4
Bone: stiffness1.32.46.2-2.5-2.02.0-1.6-1.31.3-1.3-1.41.0-0.9-2.50.3-0.2-0.6-1.31.9-1.9-1.81.21.4
Tibialis anterior weight7.224.741.2-6.1-6.46.4-6.3-6.06.0-6.0-5.76.3-6.0-3.5-5.5-4.2-5.2-4.70.4-0.10.4-2.4-1.7
Time to tail flick, vehicle, before self-admin0.30.40.8-0.6-0.50.5-0.2-0.60.6-0.6-0.3-0.00.1-0.90.20.90.30.20.9-0.9-0.80.70.8
Time to tail flick, vehicle, after self-admin0.71.54.1-1.0-0.90.8-0.3-0.90.9-1.0-1.0-0.10.2-1.30.40.71.21.22.0-2.0-2.01.71.8
Time to tail flick, test, before self-admin2.22.56.51.21.5-1.51.70.7-0.70.71.2-1.91.90.21.72.32.42.51.1-1.3-1.41.71.6
Time to tail flick, test, after self-admin0.10.10.3-0.1-0.30.3-0.20.1-0.10.10.10.2-0.2-0.10.20.0-0.5-0.6-0.30.10.1-0.3-0.3
Delta time to tail flick, vehicle, before/after SA0.50.51.7-0.6-0.60.6-0.4-0.50.5-0.6-0.90.2-0.2-0.50.1-0.30.40.61.0-1.3-1.30.80.9
Delta time to tail flick, test, before/after SA2.83.58.2-0.9-1.51.5-1.8-0.70.7-0.7-0.92.1-2.20.3-2.1-2.5-2.9-2.9-1.91.92.0-2.5-2.4
Tibia length0.92.412.2-2.1-1.71.8-1.6-0.90.9-0.9-0.51.6-1.5-1.9-1.4-0.9-2.1-3.5-0.40.70.8-1.1-1.0
Ambulatory time before self-admin0.20.52.7-1.2-0.70.7-0.30.2-0.20.2-0.10.00.1-1.60.70.3-0.1-1.21.0-0.7-0.60.80.8
Ambulatory time after self-admin0.40.61.90.10.5-0.40.71.3-1.31.20.8-0.80.8-0.51.40.40.5-0.50.5-0.2-0.30.80.7
Bone: tissue strength0.10.10.4-0.2-0.10.00.10.1-0.10.10.1-0.20.2-0.30.50.60.20.00.3-0.4-0.40.40.4
Total heroin consumption3.13.77.5-2.7-2.72.7-2.5-2.02.0-1.9-2.42.3-2.2-1.8-1.6-1.9-1.9-1.70.9-0.8-0.7-0.20.1
Bone: trabecular number0.91.66.1-1.4-0.91.1-0.7-0.70.7-0.6-0.50.0-0.0-1.71.20.40.2-0.22.0-2.5-2.41.71.8
Bone: trabecular spacing0.30.41.31.00.7-0.80.60.3-0.30.30.2-0.30.31.1-0.3-0.20.40.9-0.60.80.8-0.4-0.5
Bone: trabecular thickness0.70.92.00.30.9-0.70.80.7-0.70.70.8-1.11.1-0.31.40.71.10.90.9-1.3-1.41.31.2
Bone: trabecular tissue density2.34.07.32.42.6-2.72.52.6-2.62.62.6-2.02.01.30.71.41.20.4-1.72.22.0-0.6-1.0
Water consumed over 24 hours0.51.02.5-0.8-1.21.2-1.3-1.31.3-1.3-1.31.2-1.30.1-0.8-1.6-1.0-0.30.1-0.7-0.6-0.3-0.2
Number of responses in last shaping day0.10.10.70.40.1-0.0-0.10.4-0.40.2-0.10.2-0.20.8-0.2-0.7-0.20.6-0.40.30.3-0.4-0.4