Hub : Genes

Fam124a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Fam124a 0.06 0.04 5.7e-04 0.05 0.05 0.05 0.05 7.8e-04 1.1e-03 7.4e-04 8.4e-04
2 IC gene expression Fam124a 0.07 0.05 7.1e-03 0.05 0.02 0.03 0.03 3.7e-03 5.9e-02 2.2e-02 1.7e-02
3 pVTA gene expression Fam124a 0.04 0.03 1.4e-03 0.01 0.03 0.03 0.02 3.1e-02 9.0e-04 2.2e-03 4.7e-03
4 pVTA alternative polyA XM_001080220.8 0.03 0.02 3.3e-03 0.02 0.01 0 0 1.4e-02 5.0e-02 2.8e-01 2.5e-01
5 pVTA alternative polyA XM_063274874.1 0.02 0.02 6.6e-03 0.01 0.01 0 0 3.2e-02 5.0e-02 2.1e-01 2.1e-01
6 NAcc mRNA stability Fam124a 0.01 0.01 3.5e-03 0.02 0.01 0.01 0.01 7.8e-04 3.0e-03 7.4e-03 3.0e-03
7 PL gene expression Fam124a 0.06 0.05 1.4e-03 0.03 0.03 0.02 0.03 2.1e-04 7.8e-04 1.6e-03 4.4e-04
8 NAcc intron excision ratio chr15_40984244_41028658 0.03 0.03 3.8e-03 0.01 0.01 0.01 0.01 2.1e-03 5.5e-03 6.3e-03 5.8e-03
9 BLA gene expression Fam124a 0.05 0.03 6.5e-03 0.01 0.02 0.02 0.01 6.7e-02 2.1e-02 4.3e-02 8.5e-02
10 Adipose gene expression Fam124a 0.04 0.03 8.5e-04 0 0.01 0 0 1.3e-01 1.5e-02 8.6e-02 1.3e-01
11 Brain mRNA stability Fam124a 0.04 0.03 6.0e-03 0.01 0.02 0.01 0.01 4.3e-02 9.3e-03 8.5e-02 2.7e-02
12 IC intron excision ratio chr15_41010118_41028658 0.11 0.07 8.2e-03 0.01 0.06 0.06 0.02 7.4e-02 1.3e-03 2.3e-03 3.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.20.31.1-0.40.40.5-0.50.5-0.20.20.30.4-1.00.70.7
Area under the delay curve2.84.27.12.3-1.8-2.21.9-1.92.0-2.1-2.2-2.32.7-1.6-1.3
BMI with tail0.93.16.01.8-1.7-2.42.2-2.21.6-1.6-1.5-1.21.91.21.2
BMI without tail0.10.41.50.3-0.6-0.70.3-0.30.5-0.5-0.10.00.31.21.1
Body weight1.25.28.62.3-2.6-2.92.4-2.42.5-2.5-2.3-2.32.30.60.7
Weight adjusted by age0.61.92.81.7-1.4-1.51.5-1.51.4-1.5-1.7-1.41.00.70.7
Bone surface0.20.41.3-0.50.60.7-0.80.8-0.50.50.40.5-1.20.50.5
Bone volume0.10.20.6-0.40.30.3-0.60.6-0.20.20.20.4-0.80.50.6
Breakpoint value in progressive ratio session0.30.51.10.3-0.4-0.70.8-0.81.0-1.00.3-0.90.9-0.1-0.2
Number of licking bursts0.10.20.40.3-0.5-0.60.5-0.50.3-0.4-0.30.00.50.50.6
Context. condit. distance diff. score0.20.31.3-0.40.20.4-0.30.3-0.30.30.30.30.2-1.2-1.0
Locomotion velocity, session 11.01.11.61.0-1.2-1.11.2-1.21.1-1.2-0.9-1.21.10.40.2
Locomotion distance, session 10.91.11.81.2-1.3-0.81.2-1.21.2-1.1-1.3-1.10.70.50.3
Locomotion velocity, session 20.70.81.70.9-1.3-0.90.7-0.71.3-1.2-1.2-0.90.6-0.00.2
Locomotion distance, session 20.30.40.90.5-0.7-0.10.3-0.30.8-0.7-0.6-0.3-0.41.00.9
Locomotion velocity, session 31.21.42.31.3-1.4-1.01.3-1.31.5-1.4-1.4-1.10.80.40.4
Locomotion distance, session 31.31.52.91.5-1.6-1.11.0-1.01.5-1.5-1.7-1.01.10.20.3
Stereotopy head waving bouts, day 30.70.91.7-1.11.31.2-0.70.7-1.00.91.30.9-1.0-0.1-0.2
Stereotopy head waving duration, day 30.10.10.2-0.10.30.10.5-0.50.0-0.10.4-0.20.10.0-0.1
Locomotion velocity, session 70.20.21.00.0-0.4-0.2-0.50.50.3-0.2-0.30.5-0.20.81.0
Locomotion distance, session 71.21.52.5-1.31.21.4-1.61.6-1.31.21.01.5-1.40.00.2
Stereotopy head waving bouts, day 72.22.64.11.8-1.5-1.72.0-2.01.7-1.8-1.6-1.71.50.50.3
Stereotopy head waving duration, day 73.44.26.42.4-2.1-2.12.5-2.52.2-2.4-2.1-2.12.00.40.3
Locomotion velocity, session 80.91.01.91.0-1.4-0.60.7-0.71.3-1.2-1.2-1.10.8-1.0-0.8
Locomotion distance, session 80.20.20.40.5-0.6-0.00.4-0.40.6-0.6-0.6-0.50.3-0.5-0.5
Degree of sensitization distance6.16.69.1-2.82.92.5-2.72.7-3.03.02.82.9-2.60.20.3
Degree of sensitization stereotypy2.93.24.32.0-1.8-1.82.0-2.01.9-2.0-1.9-2.11.9-0.2-0.3
Conditioned locomotion1.01.26.5-0.70.31.0-0.60.6-0.50.50.3-0.1-0.1-2.5-2.3
Cocaine response after cond. corrected0.30.41.0-0.80.40.2-0.60.6-0.40.40.70.70.5-1.0-0.8
Cocaine response after cond. not corrected0.20.31.0-0.60.40.2-0.60.6-0.30.30.60.60.4-1.0-0.8
Cocaine response before conditioning0.30.40.70.9-0.7-0.40.6-0.60.7-0.6-0.8-0.90.30.30.1
Saline control response0.40.62.3-0.40.51.1-0.40.4-0.50.50.4-0.5-0.5-1.2-1.5
Bone: connectivity density0.60.92.7-0.90.91.4-1.01.0-0.80.80.80.6-1.60.30.1
Bone: cortical apparent density0.50.82.00.8-0.8-1.01.3-1.30.8-0.8-0.7-0.51.40.30.1
Bone: cortical area0.10.10.50.5-0.1-0.7-0.00.00.2-0.2-0.40.10.40.20.5
Bone: cortical porosity2.12.34.01.6-1.6-1.11.1-1.11.7-1.7-1.5-2.01.6-1.5-1.4
Bone: cortical porosity2.12.44.81.6-1.5-0.91.1-1.11.6-1.7-1.4-2.21.6-1.7-1.7
Bone: cortical thickness0.40.61.61.1-0.6-1.30.7-0.70.7-0.7-0.8-0.51.2-0.00.2
Bone: cortical thickness1.41.73.51.5-1.3-1.71.2-1.21.5-1.4-1.3-1.11.9-0.3-0.1
Bone: cortical tissue density0.50.71.90.7-0.7-1.01.3-1.30.7-0.7-0.6-0.51.40.30.1
Condit. Reinf. active minus inactive responses1.01.11.61.0-1.1-1.11.3-1.31.1-1.1-0.7-1.20.61.20.9
Condit. Reinf. active-inactive response ratio0.20.21.3-0.40.2-0.00.1-0.1-0.20.10.60.3-0.21.10.9
Condit. Reinf. active responses1.41.83.61.2-1.3-1.31.6-1.61.6-1.6-0.9-1.91.20.60.2
Condit. Reinf. inactive responses1.11.53.81.2-1.1-0.71.2-1.21.3-1.2-1.1-1.91.2-0.9-1.2
Incentive salience index mean2.02.63.81.6-1.7-1.91.9-1.91.7-1.7-1.4-1.91.31.00.8
Condit. Reinf. lever presses2.43.75.81.9-1.9-2.42.3-2.32.0-2.0-1.8-2.21.80.70.7
Condit. Reinf. active minus inactive responses0.00.00.10.2-0.10.00.2-0.2-0.00.00.0-0.20.30.2-0.1
Condit. Reinf. active-inactive response ratio0.20.30.90.5-0.3-0.50.7-0.70.4-0.4-0.3-0.20.30.90.7
Condit. Reinf. active responses0.10.20.40.5-0.4-0.10.7-0.70.3-0.3-0.3-0.60.6-0.1-0.4
Condit. Reinf. inactive responses0.40.61.4-0.70.71.1-0.60.6-0.90.90.60.2-0.5-1.0-1.2
Condit. Reinf. lever presses2.43.56.72.0-2.0-1.52.6-2.61.9-1.9-1.8-1.91.21.30.9
Condit. Reinf. lever reinforcers received0.30.40.90.7-0.6-0.30.9-0.90.4-0.5-0.5-0.80.70.0-0.3
Conditioned reinforcement - actives2.28.712.1-3.33.43.2-3.23.2-3.43.53.42.5-2.8-1.2-1.3
Conditioned reinforcement - inactives2.36.29.9-2.72.52.7-2.72.7-2.72.82.62.6-3.10.50.5
Conditioned locomotion2.23.24.5-2.02.11.8-2.02.0-1.92.12.01.4-1.0-1.6-1.5
Patch foraging indifference point 0 sec0.00.00.2-0.00.00.2-0.20.2-0.00.0-0.0-0.0-0.5-0.10.0
Patch foraging indifference point AUC0.10.41.3-0.20.3-0.00.4-0.4-0.30.30.11.0-0.01.11.1
Delay disc. indifference point, 0s delay0.30.41.10.5-0.5-0.20.5-0.50.4-0.4-0.5-0.70.6-1.0-1.0
Delay disc. indifference point, 16s delay1.11.64.01.2-1.1-0.80.8-0.80.9-0.8-1.3-1.41.7-2.0-1.8
Delay disc. indifference point, 2s delay1.71.92.81.6-1.3-1.21.5-1.51.3-1.4-1.4-1.71.6-0.9-0.9
Delay disc. indifference point, 24s delay0.40.71.51.1-0.7-1.10.7-0.70.7-0.8-1.1-0.71.2-0.4-0.2
Delay disc. indifference point, 4s delay3.94.16.42.1-1.8-2.11.9-1.92.2-2.3-2.0-2.52.5-1.4-1.2
Delay disc. indifference point, 8s delay1.93.25.42.1-1.6-2.21.7-1.71.8-1.8-2.1-1.82.3-1.1-0.7
Indifference point function ln k0.20.51.30.6-0.7-0.60.1-0.10.6-0.6-0.6-1.20.6-1.0-0.8
Indifference point function log k0.20.51.30.6-0.7-0.60.1-0.10.6-0.6-0.6-1.20.6-1.0-0.8
Patch foraging total patch changes 0 sec0.00.10.20.5-0.4-0.30.3-0.30.4-0.4-0.5-0.50.1-0.3-0.1
Patch foraging total patch changes 12 sec0.50.71.50.5-0.7-0.71.1-1.10.8-0.6-0.6-0.20.31.21.1
Patch foraging total patch changes 18 sec0.10.20.50.10.1-0.20.7-0.70.4-0.4-0.0-0.10.6-0.1-0.2
Patch foraging total patch changes 24 sec0.30.92.70.9-0.9-0.51.7-1.71.0-0.8-0.8-0.80.8-0.1-0.2
Patch foraging total patch changes 6 sec0.10.21.10.1-0.1-0.20.3-0.3-0.10.1-0.10.5-0.21.01.1
Patch foraging time to switch 0 sec0.00.20.5-0.40.20.7-0.30.3-0.20.20.30.1-0.4-0.7-0.7
Patch foraging water rate 0 sec0.31.21.81.3-1.3-1.20.8-0.81.2-1.2-1.3-1.31.2-0.2-0.1
Patch foraging water rate 12 sec0.93.67.32.0-1.9-1.41.7-1.72.1-2.1-1.8-2.72.1-1.2-1.4
Patch foraging water rate 18 sec3.37.49.93.1-3.1-3.02.6-2.63.1-3.1-2.9-2.93.1-0.2-0.1
Patch foraging water rate 24 sec0.91.33.10.8-0.6-0.80.8-0.81.1-1.3-0.6-1.81.4-1.4-1.5
Patch foraging water rate 6 sec2.13.15.71.6-1.6-1.31.7-1.71.9-2.1-1.4-2.42.0-1.4-1.5
Seeking ratio, delayed vs. immediate footshock0.91.42.9-0.91.00.8-1.71.7-1.21.20.50.6-0.8-1.5-1.2
Distance traveled before self-admin0.10.30.80.3-0.00.10.6-0.60.4-0.4-0.1-0.80.3-0.8-0.9
Distance traveled after self-admin0.30.52.4-0.20.40.3-0.50.5-0.40.50.1-0.30.1-1.5-1.4
Extensor digitorum longus weight6.827.135.05.8-5.8-5.75.5-5.55.8-5.7-5.6-5.55.9-1.3-0.9
Bone: elastic displacement0.50.61.8-0.70.41.2-0.60.6-0.30.30.5-0.1-0.5-1.2-1.3
Bone: elastic work0.20.20.60.3-0.4-0.00.6-0.60.6-0.5-0.2-0.80.2-0.5-0.6
Bone: endosteal estimation0.40.91.9-0.90.80.9-1.21.2-1.01.00.60.9-1.40.30.4
Bone: endosteal perimeter0.71.72.9-1.41.31.5-1.61.6-1.41.31.11.2-1.7-0.2-0.1
Epididymis fat weight0.31.57.90.3-0.20.50.2-0.20.2-0.2-0.5-1.30.8-2.7-2.8
Delta time in closed arm before/after self-admin0.10.10.20.30.0-0.40.4-0.40.2-0.10.1-0.10.4-0.4-0.2
Delta time in open arm before/after self-admin1.41.73.2-0.91.00.8-1.41.4-1.41.30.31.8-1.51.51.5
Diff in mean of infusions in LGA sessions0.30.51.00.7-0.6-0.80.8-0.80.8-1.0-0.6-0.80.5-0.4-0.2
Delay discount exponential model param4.05.58.8-2.72.12.6-2.32.3-2.42.42.62.6-3.01.41.2
Extinction: sum of active levers before priming0.10.20.40.1-0.2-0.10.5-0.50.4-0.40.3-0.50.5-0.5-0.6
Active lever presses in extinction session 60.10.10.60.0-0.00.30.3-0.30.2-0.10.2-0.40.2-0.7-0.8
Bone: final force0.81.31.71.3-1.1-1.31.3-1.31.1-1.1-1.1-1.31.2-0.6-0.3
Bone: final moment0.91.52.21.4-1.2-1.21.5-1.51.3-1.2-1.2-1.51.1-0.6-0.4
Food consumed during 24 hour testing period0.10.10.50.2-0.3-0.30.3-0.30.4-0.4-0.2-0.30.00.70.5
Glucose0.30.51.90.5-0.5-0.80.6-0.60.5-0.5-0.50.20.41.31.4
Heart weight0.00.10.20.0-0.1-0.30.1-0.10.2-0.10.3-0.20.40.40.2
Delay discount hyperbolic model param3.84.97.7-2.52.02.3-2.12.1-2.22.32.42.5-2.81.51.2
Intermittent access intake day 1-15 change0.42.04.6-1.72.11.8-1.11.1-1.41.32.01.1-1.6-0.2-0.3
Intermittent access intake escalation0.21.33.3-1.41.81.4-0.80.8-1.11.01.60.8-1.2-0.2-0.4
Intermittent access intake escalation 20.50.81.8-1.11.31.0-0.60.6-0.80.91.10.9-1.00.30.2
Intermitt. access day 1 inactive lever presses0.67.411.1-2.92.92.2-2.92.9-2.93.02.93.3-3.11.31.6
Intermitt. access day 15 inactive lever presses0.31.83.6-1.51.61.4-1.41.4-1.31.41.41.2-1.90.30.3
Intermitt. access escalation Index0.20.52.00.5-0.3-0.80.5-0.50.3-0.5-0.50.30.31.31.4
Intermittent access day 1 total infusions0.41.31.8-1.31.31.2-1.11.1-1.21.31.31.0-0.7-1.2-1.0
Intermittent access day 15 total infusions1.33.36.0-2.12.42.1-1.61.6-1.91.82.31.5-1.7-1.0-0.9
Intermittent access terminal intake (last 3 days)1.93.35.5-2.22.42.1-1.61.6-1.91.92.21.9-1.8-0.5-0.4
Intermittent access total infusions3.74.47.5-2.52.72.2-2.12.1-2.32.32.62.0-1.8-1.1-0.9
Intermittent access day 1 locomotion0.20.30.5-0.60.60.2-0.70.7-0.50.60.60.6-0.1-0.6-0.3
Intermittent access day 15 total locomotion0.62.14.4-1.82.11.5-1.31.3-1.41.62.11.4-1.2-0.6-0.4
Intermittent access total locomotion1.41.73.4-1.61.81.0-1.21.2-1.31.41.81.2-0.9-0.7-0.5
Intermittent access standard deviation0.21.32.6-1.21.61.6-0.70.7-0.80.91.40.2-0.9-1.3-1.5
Left kidney weight0.86.28.52.5-2.8-2.92.7-2.72.9-2.8-2.4-2.42.01.61.5
Right kidney weight1.510.714.13.5-3.5-3.83.7-3.73.7-3.7-3.2-3.42.81.81.6
Cocaine induced anxiety0.51.21.91.3-1.2-1.01.0-1.00.8-0.9-1.3-1.41.3-1.2-1.0
Post-drug Anxiety0.20.20.80.5-0.5-0.10.2-0.20.1-0.2-0.5-0.80.1-0.9-0.8
Baseline Anxiety0.20.30.8-0.40.30.4-0.40.4-0.30.30.40.5-0.70.90.7
Tail length0.00.20.80.0-0.50.30.1-0.10.6-0.6-0.1-0.9-0.1-0.1-0.4
Length with tail0.00.20.90.1-0.6-0.30.1-0.10.6-0.6-0.3-1.0-0.0-0.4-0.4
Length without tail0.41.93.31.4-1.5-1.81.5-1.51.5-1.3-1.6-1.71.3-0.4-0.1
Times rat made contact with spout0.40.40.70.7-0.8-0.60.6-0.60.8-0.8-0.6-0.60.10.60.6
Lifetime Intake3.74.67.2-2.42.72.2-2.22.2-2.42.42.52.0-1.8-1.1-0.9
Liver weight, left1.42.34.21.6-1.4-1.62.1-2.11.6-1.5-1.2-2.01.70.1-0.1
Liver weight, right0.10.20.60.4-0.5-0.70.1-0.10.3-0.3-0.4-0.30.8-0.3-0.2
Locomotor activity3.14.98.32.4-2.6-2.22.1-2.12.7-2.8-2.2-2.92.1-0.6-0.6
Locomotor testing distance0.10.31.10.3-0.5-0.00.1-0.10.6-0.8-0.3-1.0-0.0-0.5-0.6
Locomotor testing rearing0.10.41.60.3-0.70.20.2-0.20.3-0.4-0.4-0.5-0.91.31.0
Locomotion in novel chamber1.41.82.81.4-1.7-1.11.5-1.51.7-1.6-1.3-1.71.3-0.0-0.2
Locomotion in novel chamber post-restriction0.10.41.30.7-0.8-0.2-0.00.00.4-0.5-1.1-0.50.2-1.0-0.6
Fecal boli incidents, locomotor time 11.12.94.32.1-2.1-1.91.7-1.71.8-1.9-2.1-1.11.70.90.9
Change in fecal boli incidents, locomotor task0.70.71.4-1.00.90.9-1.01.0-0.80.80.80.7-1.2-0.5-0.2
Time >=10cm from walls, locomotor time 10.10.10.50.30.00.20.5-0.50.3-0.5-0.1-0.7-0.2-0.2-0.4
Bouts of movement, locomotor time 10.60.81.50.9-0.9-1.20.7-0.71.1-1.1-1.0-0.50.60.80.9
Total resting periods, locomotor time 10.60.71.40.8-0.7-1.20.6-0.61.1-1.1-0.8-0.30.70.80.9
Rest time, locomotor task time 11.72.74.71.4-1.2-2.11.6-1.61.8-1.7-1.3-0.51.32.12.2
Distance moved, locomotor task time 10.71.93.4-1.31.11.8-1.31.3-1.61.61.30.6-1.2-1.5-1.6
Vertical activity count, locomotor time 10.32.27.3-1.10.91.8-1.21.2-1.00.91.1-0.2-0.7-2.6-2.7
Time >=10cm from walls, locomotor time 20.10.20.7-0.20.20.60.0-0.0-0.10.10.3-0.4-0.5-0.8-0.8
Bouts of movement, locomotor time 20.10.51.80.7-0.8-1.30.2-0.20.5-0.4-0.90.00.70.50.9
Total resting periods, locomotor time 20.20.92.80.9-1.0-1.70.5-0.50.8-0.7-1.1-0.00.90.91.3
Rest time, locomotor task time 21.93.26.01.7-1.7-2.51.7-1.71.9-1.8-1.8-0.71.71.92.1
Distance moved, locomotor task time 20.91.24.9-0.70.71.5-0.40.4-0.90.90.8-0.3-0.5-1.9-2.2
Vertical activity count, locomotor time 21.22.710.9-1.11.21.8-1.01.0-1.21.11.3-0.4-0.3-3.0-3.3
Light reinforcement 10.21.02.11.2-1.2-0.80.9-0.91.2-1.4-1.2-1.20.8-0.4-0.4
Light reinforcement 20.40.82.0-0.50.50.8-1.41.4-0.70.70.40.6-0.3-1.4-1.2
Bone: marrow area0.40.92.0-1.00.81.0-1.31.3-1.01.00.61.0-1.40.20.4
Bone: maximum diameter0.30.71.8-0.70.70.4-1.31.3-0.80.90.51.0-0.5-0.4-0.1
Bone: maximum force0.71.31.91.2-1.0-1.11.3-1.31.1-1.0-1.0-1.41.2-1.1-0.8
Bone: maximum moment0.81.52.51.4-1.1-1.11.5-1.51.2-1.2-1.1-1.61.2-1.0-0.8
Mean time between licks in bursts0.10.91.5-1.10.90.9-0.60.6-0.80.81.11.1-1.01.21.0
Mean num. licks in bursts0.00.00.20.2-0.10.1-0.10.10.3-0.2-0.1-0.4-0.20.1-0.0
Cd content in liver0.50.62.30.5-0.5-0.50.4-0.40.6-0.6-0.7-0.4-0.21.51.4
Co content in liver0.81.01.41.1-1.1-1.21.0-1.01.1-1.1-1.1-0.91.2-0.5-0.2
Cu content in liver1.82.23.01.6-1.5-1.71.7-1.71.5-1.5-1.5-1.01.01.21.3
Fe content in liver1.01.21.9-1.21.11.4-1.31.3-1.11.11.40.8-1.30.2-0.0
K content in liver0.30.31.4-0.10.30.60.1-0.1-0.20.20.10.2-0.1-1.2-1.0
Mg content in liver1.21.32.5-1.21.31.6-1.11.1-1.21.21.11.1-1.4-0.5-0.4
Mn content in liver0.91.11.7-1.01.31.3-0.70.7-1.21.21.00.8-0.9-1.0-0.9
Na content in liver1.92.13.51.6-1.5-1.41.9-1.91.4-1.4-1.5-1.81.3-0.6-0.6
Rb content in liver2.32.74.1-1.71.82.0-1.81.8-1.71.71.71.5-2.0-0.4-0.3
Se content in liver1.72.03.9-1.51.41.5-2.02.0-1.51.51.31.2-1.6-0.4-0.3
Sr content in liver1.21.03.5-0.70.60.4-0.70.7-0.60.60.61.1-1.11.91.7
Zn content in liver0.20.20.6-0.20.30.30.1-0.1-0.20.20.30.4-0.70.70.7
Bone: minimum diameter0.10.20.4-0.10.40.0-0.70.7-0.40.40.20.5-0.40.20.4
Time in familiar zone, hab. session 10.20.20.50.2-0.1-0.30.5-0.50.3-0.3-0.0-0.50.7-0.4-0.5
Time in novel zone, hab. session 10.10.10.4-0.20.20.2-0.50.5-0.30.30.10.6-0.50.20.4
Total zone transitions, hab. session 10.71.01.71.2-1.3-1.11.1-1.10.9-0.9-1.2-0.71.10.10.2
Total locomotion distance, hab. session 10.10.10.50.3-0.3-0.20.7-0.70.2-0.3-0.3-0.30.3-0.3-0.2
Locomotion velocity, hab. session 10.20.30.70.4-0.5-0.20.9-0.90.4-0.4-0.4-0.70.4-0.5-0.6
Time in familiar zone, hab. session 20.91.13.1-1.10.81.1-0.90.9-0.90.81.00.1-0.3-1.7-1.8
Time in novel zone, hab. session 20.70.72.01.0-0.8-0.70.7-0.70.7-0.7-1.0-0.00.11.41.4
Total zone transitions, hab. session 22.53.24.82.0-2.2-1.52.0-2.02.0-1.9-2.2-2.01.6-0.5-0.4
Total locomotion distance, hab. session 21.62.23.01.4-1.7-1.21.7-1.71.7-1.7-1.7-1.61.4-0.8-0.6
Locomotion velocity, hab. session 21.82.33.11.6-1.8-1.41.7-1.71.8-1.8-1.7-1.71.4-0.7-0.5
Novel to familiar place preference ratio0.91.22.0-1.21.10.9-1.21.2-0.91.01.31.2-1.40.50.6
Novelty place preference0.81.02.1-1.11.00.8-1.11.1-0.80.81.21.0-1.40.50.7
Time in novel zone, NPP test0.80.92.1-1.11.00.8-1.11.1-0.70.81.11.0-1.50.50.7
Total zone transitions, NPP test1.01.52.21.5-1.4-1.21.5-1.51.3-1.3-1.4-1.21.00.30.3
Total locomotion distance, NPP test0.20.31.5-0.1-0.10.00.3-0.30.1-0.10.10.4-0.61.21.2
Locomotion velocity, NPP test0.20.31.40.1-0.1-0.10.5-0.50.2-0.20.00.3-0.41.21.2
Intraocular pressure2.43.96.8-2.22.02.6-2.42.4-2.11.92.11.3-2.30.1-0.4
Delta distance traveled before/after self-admin1.31.43.1-1.11.00.5-1.71.7-1.61.50.51.4-1.00.20.5
Delta ambulatory time before/after self-admin0.50.91.8-0.90.90.6-1.31.3-1.31.30.61.1-0.7-0.20.0
Parametrial fat weight1.22.94.4-2.11.81.9-2.12.1-1.61.71.91.2-1.5-1.0-1.0
Pavlov. Cond. lever latency1.01.33.4-1.21.11.8-1.01.0-0.90.91.20.9-1.1-1.1-1.1
Pavlov. Cond. magazine entry latency0.10.20.4-0.10.5-0.2-0.20.2-0.60.60.30.2-0.40.70.6
Pavlov. Cond. change in total contacts0.40.51.70.8-0.5-1.30.5-0.50.4-0.4-0.7-0.60.50.70.8
Pavlov. Cond. index score1.41.84.71.5-1.4-2.21.2-1.21.1-1.1-1.5-1.21.31.01.1
Pavlov. Cond. latency score1.21.53.91.3-1.2-2.01.1-1.10.9-0.9-1.3-1.01.11.11.2
Pavlov. Cond. lever contacts0.91.13.11.0-0.9-1.80.9-0.90.8-0.8-1.0-0.80.91.01.1
Pavlov. Cond. magazine entry number0.50.71.8-1.00.71.3-0.90.9-0.60.60.80.8-0.7-0.7-0.7
Pavlov. Cond. intertrial magazine entries1.01.22.31.1-1.1-0.81.3-1.31.3-1.3-1.0-1.51.2-0.4-0.6
Pavlov. Cond. lever-magazine prob. diff.1.51.95.01.5-1.4-2.21.3-1.31.1-1.2-1.5-1.11.31.01.2
Pavlov. Cond. response bias0.91.12.91.2-0.9-1.71.1-1.10.9-0.9-1.0-1.01.10.50.6
Pavlov. Cond. lever latency2.73.86.6-2.32.21.6-2.62.6-2.01.92.12.0-1.3-1.0-0.7
Pavlov. Cond. magazine entry latency1.11.53.01.3-1.2-1.11.3-1.31.2-1.3-1.1-1.71.4-0.8-0.9
Pavlov. Cond. change in total contacts2.04.87.62.5-2.4-1.92.8-2.82.4-2.3-2.3-2.41.90.1-0.1
Pavlov. Cond. index score2.43.86.12.3-2.1-1.82.5-2.52.0-2.0-2.0-2.31.70.2-0.1
Pavlov. Cond. latency score2.23.65.82.2-2.0-1.72.4-2.42.0-2.0-1.9-2.31.70.1-0.1
Pavlov. Cond. lever contacts2.84.17.22.4-2.3-1.72.7-2.72.1-2.1-2.2-2.11.40.90.6
Pavlov. Cond. magazine entry number1.41.82.5-1.51.51.2-1.51.5-1.41.41.31.6-1.40.20.4
Pavlov. Cond. intertrial magazine entries1.83.96.1-2.11.81.9-1.91.9-1.81.81.92.3-2.51.91.6
Pavlov. Cond. lever-magazine prob. diff.2.33.55.92.2-2.0-1.72.4-2.41.9-1.9-1.9-2.21.80.0-0.2
Pavlov. Cond. response bias3.14.36.62.5-2.4-1.82.6-2.62.2-2.2-2.3-2.31.70.40.1
Time in closed arm before self-admin0.50.91.51.1-1.1-1.10.9-0.91.1-1.1-1.2-0.90.8-0.00.2
Time in closed arm after self-admin1.92.23.71.7-1.4-1.91.6-1.61.6-1.6-1.3-1.61.8-0.6-0.3
Time in open arm before self-admin0.50.62.80.1-0.20.50.3-0.30.6-0.40.0-1.10.3-1.4-1.7
Time in open arm after self-admin0.80.81.7-0.70.70.9-0.80.8-0.90.80.41.1-1.31.21.1
Bone: periosteal estimation0.20.61.1-0.50.70.4-1.11.1-0.80.80.41.0-0.90.30.6
Bone: periosteal perimeter0.20.40.9-0.40.60.3-0.90.9-0.60.60.30.8-0.70.30.5
Bone: post-yield work0.10.21.00.1-0.1-0.30.2-0.20.1-0.1-0.10.10.9-1.0-0.7
Progressive ratio test 1 active lever presses0.71.32.0-1.31.21.1-1.21.2-1.41.31.21.3-1.1-0.2-0.1
Progressive ratio test 1 breakpoint0.61.11.7-1.11.11.0-1.11.1-1.31.21.11.2-1.0-0.2-0.1
Progressive ratio test 1 inactive lever presses0.82.23.7-1.61.31.7-1.41.4-1.61.61.51.7-1.90.70.7
Progressive ratio test 2 active lever presses2.12.94.6-1.81.91.5-1.41.4-1.91.81.92.1-2.11.11.2
Progressive ratio test 2 breakpoint1.92.44.0-1.61.71.3-1.31.3-1.71.61.71.9-2.01.11.1
Progressive ratio test 2 inactive lever presses1.34.06.2-2.12.31.7-1.71.7-2.12.12.22.5-2.41.51.5
Incentive Sensitization - Responses0.82.13.9-1.41.51.2-0.90.9-1.41.21.71.6-2.01.61.4
Incentive Sensitization - Breakpoint0.81.93.9-1.31.41.2-0.90.9-1.31.11.61.5-2.01.71.5
Sum of active levers in priming session hrs 5-60.10.10.2-0.30.10.4-0.40.4-0.40.30.30.5-0.40.50.4
Progressive ratio0.10.20.40.4-0.6-0.40.4-0.40.6-0.6-0.6-0.60.5-0.2-0.2
Food seeking constrained by brief footshock0.40.61.4-0.91.00.3-0.70.7-0.70.70.81.2-0.30.60.6
Seeking ratio, punishment vs. effort0.00.10.3-0.20.5-0.0-0.10.1-0.30.30.30.40.1-0.1-0.0
Retroperitoneal fat weight0.00.00.1-0.1-0.10.2-0.20.2-0.20.20.1-0.1-0.2-0.4-0.4
Reaction time number correct0.10.31.1-0.40.10.3-0.30.3-0.40.30.50.6-0.71.00.9
Reaction time mean minus median0.00.10.50.20.20.40.2-0.20.0-0.0-0.1-0.6-0.2-0.5-0.7
Reaction time mean minus median AUC0.00.10.3-0.00.40.20.2-0.2-0.20.20.10.1-0.40.60.3
Reaction time num false alarms0.20.40.70.6-0.7-0.70.8-0.80.8-0.7-0.3-0.80.10.40.5
Reaction time num false alarms AUC0.40.81.30.8-0.9-1.11.1-1.11.1-1.1-0.5-0.90.50.60.7
Reaction time trials correct on left0.10.31.1-0.40.10.3-0.30.3-0.40.30.50.6-0.71.00.9
Reaction time trials on left0.10.41.4-0.50.20.4-0.40.4-0.50.40.60.7-0.81.21.0
Reaction time mean0.40.81.4-1.21.21.2-0.90.9-0.80.81.00.2-0.8-0.8-1.0
Reaction time mean AUC0.40.91.4-1.21.21.2-1.01.0-0.80.91.00.3-0.9-0.7-0.9
Median of all reaction times0.71.12.0-1.41.31.2-1.11.1-0.90.91.20.3-0.9-0.8-0.9
Reaction time omissions2.03.34.8-1.81.81.6-1.61.6-1.81.82.02.1-2.21.81.6
Reaction time false alarm rate0.71.01.71.0-1.0-1.31.1-1.11.3-1.3-0.8-1.00.90.20.3
Reaction time premature initiation rate0.50.71.80.8-0.8-0.00.8-0.80.5-0.5-0.9-1.10.6-1.3-1.3
Reaction time premature initiations0.10.20.50.3-0.40.20.3-0.30.2-0.2-0.3-0.50.1-0.6-0.7
Std. dev. reaction times0.10.51.0-0.61.01.0-0.50.5-0.70.70.70.4-0.8-0.3-0.4
Reaction time trials completed0.10.41.4-0.50.20.4-0.40.4-0.50.40.60.7-0.81.21.0
Reaction time trials AUC0.10.41.1-0.50.20.5-0.40.4-0.50.40.70.7-0.81.10.9
Run reversals in cocaine runway, females1.31.52.3-1.21.21.5-1.41.4-1.31.40.80.5-1.1-1.1-1.2
Run reversals in cocaine runway, males0.70.81.21.1-0.7-0.91.1-1.10.6-0.6-1.0-1.11.0-0.6-0.6
Latency to leave start box in cocaine runway0.60.81.4-0.90.80.9-1.21.2-0.80.90.81.1-1.10.50.5
Latency to leave start box in cocaine runway, F1.31.62.5-1.31.31.1-1.61.6-1.21.31.11.5-1.50.60.7
Latency to leave start box in cocaine runway, M0.20.20.40.4-0.6-0.30.4-0.40.6-0.6-0.3-0.30.30.50.3
Std. dev. time between licks in bursts1.42.74.8-1.72.22.0-1.41.4-2.01.91.81.3-1.9-0.5-0.6
Total sessions with >9 infusions2.22.84.4-1.92.11.3-1.81.8-2.02.02.01.6-1.3-0.6-0.4
Short access day 1 total inactive lever presses0.00.00.1-0.0-0.10.1-0.10.10.1-0.0-0.10.00.1-0.3-0.3
Short access day 10 total inactive lever presses0.10.41.6-0.50.30.3-0.50.5-0.30.40.40.9-0.51.31.1
Short access day 1 total infusions1.93.75.3-2.12.01.9-2.22.2-2.32.31.91.9-1.6-1.1-0.9
Short access day 10 total infusions0.71.12.3-1.01.10.8-1.01.0-1.11.11.00.5-0.5-1.5-1.3
Short access total infusions2.02.94.4-1.82.01.5-1.81.8-2.12.01.81.5-1.3-1.3-1.1
Short access day 1 locomotion0.20.30.5-0.60.5-0.1-0.70.7-0.70.60.50.7-0.1-0.20.1
Short access day 10 total locomotion0.00.10.60.2-0.0-0.80.4-0.40.3-0.30.0-0.30.70.10.1
Short access total locomotion0.10.10.2-0.30.5-0.5-0.20.2-0.30.20.40.20.20.00.2
One hour access (0.3 mA shock)2.12.53.9-1.72.01.6-1.51.5-1.92.01.81.9-1.50.40.3
Compulsive drug intake1.01.52.61.4-1.6-1.11.1-1.11.2-1.1-1.5-0.70.81.61.3
One hour access (shock baseline)1.74.57.5-2.42.72.3-2.02.0-2.42.32.51.9-1.9-1.2-1.0
Social response proportion2.32.94.3-1.81.51.7-2.12.1-1.81.81.81.8-2.00.50.5
Social responses1.82.33.3-1.71.71.5-1.61.6-1.71.51.81.4-1.70.70.4
Social time1.11.75.31.1-1.4-0.90.8-0.81.2-1.3-1.2-0.4-0.22.32.2
Soleus weight0.41.23.51.1-1.0-1.51.2-1.20.9-0.9-0.9-0.81.9-0.2-0.1
Bone: stiffness0.30.61.91.0-0.8-1.40.8-0.80.8-0.7-0.9-0.50.70.10.5
Tibialis anterior weight7.325.032.45.7-5.6-5.75.3-5.35.7-5.7-5.4-4.95.4-0.00.3
Time to tail flick, vehicle, before self-admin0.20.31.30.00.30.5-0.10.1-0.40.40.0-0.3-0.3-1.1-1.1
Time to tail flick, vehicle, after self-admin0.00.10.30.1-0.2-0.20.3-0.30.5-0.50.1-0.20.1-0.2-0.0
Time to tail flick, test, before self-admin0.40.51.10.8-0.9-0.41.0-1.00.6-0.7-0.4-0.70.40.40.1
Time to tail flick, test, after self-admin2.72.94.6-2.01.92.1-1.81.8-1.71.72.21.6-2.00.40.1
Delta time to tail flick, vehicle, before/after SA0.40.41.9-0.1-0.4-0.50.3-0.30.5-0.50.30.40.01.31.4
Delta time to tail flick, test, before/after SA2.32.84.1-1.91.91.9-2.02.0-1.61.71.71.6-1.80.1-0.0
Tibia length0.92.55.71.4-1.5-1.71.4-1.41.5-1.4-1.4-1.00.12.42.3
Ambulatory time before self-admin0.30.81.70.8-0.6-0.30.9-0.90.9-0.9-0.7-1.30.8-1.0-1.1
Ambulatory time after self-admin0.50.83.00.6-0.6-0.50.3-0.30.6-0.5-0.8-1.11.0-1.7-1.5
Bone: tissue strength0.40.40.8-0.80.70.8-0.40.4-0.70.70.90.4-0.70.30.0
Total heroin consumption0.40.40.80.5-0.4-0.80.8-0.80.9-0.80.0-0.70.90.50.2
Bone: trabecular number0.40.82.1-0.90.71.1-1.21.2-0.60.60.60.6-1.40.30.3
Bone: trabecular spacing0.50.72.20.6-0.6-0.90.6-0.60.6-0.6-0.5-0.71.5-1.1-1.0
Bone: trabecular thickness0.71.01.61.2-1.1-1.31.0-1.01.2-1.2-1.2-0.80.70.60.8
Bone: trabecular tissue density0.81.33.01.2-1.2-1.71.1-1.11.1-1.1-1.2-0.71.70.00.3
Water consumed over 24 hours0.10.20.30.5-0.5-0.60.3-0.30.5-0.5-0.5-0.60.20.20.3
Number of responses in last shaping day0.70.94.2-0.60.80.7-0.50.5-0.50.40.6-0.10.0-2.1-1.8