N4bp2l1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative TSS NM_001035222.2 0.1 0.06 3.2e-06 0.06 0.07 0.06 0.06 1.9e-06 8.6e-07 1.8e-06 1.4e-06
2 Brain alternative TSS XM_039089675.2 0.09 0.05 5.6e-06 0.06 0.06 0.06 0.06 3.8e-06 1.7e-06 4.0e-06 3.0e-06
3 PL alternative TSS NM_001035222.2 0.04 0.03 7.0e-04 0.02 0.02 0.03 0.02 1.3e-03 2.5e-03 5.4e-04 9.8e-04
4 pVTA gene expression N4bp2l1 0.21 0.1 7.3e-13 0.16 0.16 0.16 0.15 3.1e-13 1.2e-12 8.4e-13 4.3e-12
5 Brain gene expression N4bp2l1 0.04 0.03 1.5e-03 0.04 0.04 0.04 0.04 4.5e-05 1.5e-04 1.7e-04 7.1e-05
6 PL alternative TSS XM_039089675.2 0.04 0.03 8.4e-04 0.03 0.02 0.03 0.03 1.4e-04 2.0e-03 4.3e-04 7.4e-04
7 PL isoform ratio XM_039089675.2 0.04 0.03 1.1e-03 0.03 0.01 0.02 0.02 1.4e-04 2.0e-02 5.0e-03 1.7e-03
8 PL isoform ratio NM_001035222.2 0.05 0.03 3.1e-04 0.03 0.01 0.01 0.01 1.1e-04 3.6e-02 8.8e-03 8.1e-03
9 Liver gene expression N4bp2l1 0.21 0.1 0.0e+00 0.15 0.16 0.16 0.16 5.5e-16 1.3e-17 8.6e-18 1.1e-17
10 Adipose gene expression N4bp2l1 0.35 0.13 0.0e+00 0.26 0.26 0.27 0.27 1.4e-28 6.8e-29 1.9e-29 1.6e-29
11 Brain isoform ratio NM_001035222.2 0.04 0.03 6.4e-03 0.02 0.01 0.01 0.01 5.6e-03 2.8e-02 1.4e-02 2.2e-02
12 Brain isoform ratio XM_039089675.2 0.04 0.03 7.6e-03 0.02 0.01 0.01 0.01 5.5e-03 2.6e-02 1.4e-02 2.5e-02
13 Brain mRNA stability N4bp2l1 0.05 0.03 1.2e-03 0.04 0.03 0.03 0.03 2.1e-04 1.6e-03 1.8e-03 1.1e-03
14 IC mRNA stability N4bp2l1 0.08 0.06 7.4e-03 0.05 0.06 0.05 0.05 4.0e-03 2.6e-03 4.3e-03 3.1e-03
15 PL gene expression N4bp2l1 0.03 0.02 2.8e-03 0.01 0.01 0.01 0.01 2.3e-02 3.5e-02 2.6e-02 3.2e-02
16 Adipose alternative TSS NM_001035222.2 0.03 0.02 7.3e-03 0.01 0 0 0 3.9e-02 2.6e-01 1.4e-01 2.0e-01
17 Adipose alternative TSS XM_039089675.2 0.03 0.02 5.6e-03 0.01 0 0 0 3.4e-02 2.2e-01 1.4e-01 1.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density2.95.09.4-3.13.1-2.5-2.4-2.52.52.5-2.5-2.4-2.3-2.32.3-2.3-1.0-0.8-0.70.7
Area under the delay curve1.01.23.21.8-1.80.90.90.9-0.9-0.90.90.81.11.1-1.11.1-0.7-0.9-0.80.8
BMI with tail1.86.110.3-2.52.5-3.2-3.2-3.23.23.2-3.2-2.5-1.9-1.91.9-1.9-2.1-2.3-1.11.1
BMI without tail4.313.117.3-3.23.2-4.1-4.1-4.24.24.2-4.2-3.8-3.2-3.23.2-3.2-3.6-3.7-2.82.8
Body weight14.965.086.1-7.77.7-9.3-9.3-9.29.29.2-9.2-8.6-7.4-7.47.4-7.4-7.6-7.7-5.85.8
Weight adjusted by age0.30.51.5-1.21.2-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.70.7-0.7-0.10.2-0.10.1
Bone surface3.76.89.4-3.03.0-3.1-3.0-3.03.03.0-3.0-2.8-2.4-2.42.4-2.4-2.1-1.9-1.41.4
Bone volume1.73.15.3-2.32.3-2.2-2.1-2.12.12.1-2.1-1.8-1.5-1.51.5-1.5-1.0-0.9-0.50.5
Breakpoint value in progressive ratio session0.20.31.00.4-0.4-0.1-0.1-0.10.10.1-0.1-0.3-0.1-0.10.1-0.1-0.9-0.9-1.01.0
Number of licking bursts0.71.22.2-1.51.5-1.0-1.0-1.11.11.1-1.1-1.0-1.4-1.41.4-1.4-0.10.1-0.10.1
Context. condit. distance diff. score3.64.36.1-1.61.6-2.0-2.0-1.81.81.8-1.8-2.3-2.2-2.22.2-2.2-2.4-2.3-2.52.5
Locomotion velocity, session 10.60.71.21.1-1.11.01.10.9-0.9-0.90.90.80.80.8-0.80.80.10.1-0.10.1
Locomotion distance, session 11.72.23.51.5-1.51.81.81.9-1.9-1.91.91.51.41.4-1.41.41.01.00.6-0.6
Locomotion velocity, session 20.20.20.50.7-0.70.70.70.6-0.6-0.60.60.40.40.4-0.40.4-0.1-0.2-0.40.4
Locomotion distance, session 21.41.93.81.3-1.31.92.02.0-2.0-2.02.01.20.80.8-0.80.81.11.20.3-0.3
Locomotion velocity, session 30.20.30.7-0.20.2-0.4-0.4-0.40.40.4-0.4-0.5-0.5-0.50.5-0.5-0.7-0.8-0.70.7
Locomotion distance, session 30.10.10.4-0.20.20.20.10.1-0.1-0.10.10.0-0.4-0.40.4-0.40.60.50.4-0.4
Stereotopy head waving bouts, day 32.42.85.0-2.22.2-1.9-1.9-1.81.81.8-1.8-1.9-1.6-1.61.6-1.6-1.2-0.8-0.90.9
Stereotopy head waving duration, day 30.00.10.1-0.20.2-0.1-0.1-0.10.10.1-0.10.10.40.4-0.40.40.10.20.3-0.3
Locomotion velocity, session 70.91.02.61.6-1.60.91.00.9-0.9-0.90.90.81.21.2-1.21.2-0.5-0.6-0.60.6
Locomotion distance, session 70.40.50.91.0-1.00.80.90.8-0.8-0.80.80.30.20.2-0.20.2-0.4-0.3-0.90.9
Stereotopy head waving bouts, day 70.30.30.60.6-0.60.70.70.8-0.8-0.80.80.50.40.4-0.40.40.30.40.1-0.1
Stereotopy head waving duration, day 70.60.71.01.0-1.00.90.90.9-0.9-0.90.90.90.80.8-0.80.80.60.50.5-0.5
Locomotion velocity, session 80.20.20.80.1-0.1-0.3-0.3-0.10.10.1-0.1-0.4-0.1-0.10.1-0.1-0.9-0.8-0.90.9
Locomotion distance, session 81.01.52.7-0.80.8-1.1-1.1-0.90.90.9-0.9-1.4-1.3-1.31.3-1.3-1.6-1.5-1.61.6
Degree of sensitization distance1.01.12.11.4-1.41.21.31.2-1.2-1.21.20.91.01.0-1.01.0-0.00.2-0.30.3
Degree of sensitization stereotypy0.50.51.01.0-1.00.90.80.8-0.8-0.80.80.80.70.7-0.70.70.40.30.2-0.2
Conditioned locomotion0.10.10.3-0.40.4-0.2-0.2-0.20.20.2-0.20.0-0.1-0.10.1-0.10.40.50.6-0.6
Cocaine response after cond. corrected0.60.71.7-0.30.3-1.1-1.1-1.31.31.3-1.3-0.10.20.2-0.20.20.0-0.61.0-1.0
Cocaine response after cond. not corrected0.40.51.2-0.00.0-0.9-0.9-1.11.11.1-1.1-0.10.20.2-0.20.2-0.4-1.00.5-0.5
Cocaine response before conditioning0.30.41.90.4-0.40.40.40.5-0.5-0.50.5-0.3-0.3-0.30.3-0.3-0.8-0.7-1.41.4
Saline control response3.03.97.3-2.32.3-1.4-1.5-1.41.41.4-1.4-2.3-2.7-2.72.7-2.7-1.3-0.9-1.91.9
Bone: connectivity density5.38.312.4-3.53.5-3.1-3.0-3.13.13.1-3.1-3.2-3.0-3.03.0-3.0-2.1-1.8-1.81.8
Bone: cortical apparent density0.20.31.01.0-1.00.40.40.4-0.4-0.40.40.50.70.7-0.70.7-0.1-0.30.1-0.1
Bone: cortical area1.82.85.7-1.01.0-1.7-1.7-1.61.61.6-1.6-1.8-1.3-1.21.2-1.2-2.4-2.3-2.22.2
Bone: cortical porosity0.10.10.2-0.40.4-0.1-0.20.0-0.0-0.00.0-0.2-0.3-0.30.3-0.30.20.20.1-0.1
Bone: cortical porosity0.10.20.40.2-0.20.50.50.6-0.6-0.60.60.30.20.2-0.20.20.30.40.1-0.1
Bone: cortical thickness1.62.64.7-1.11.1-1.7-1.7-1.61.61.6-1.6-1.8-1.3-1.31.3-1.3-2.2-2.1-1.91.9
Bone: cortical thickness1.41.62.7-1.01.0-1.1-1.1-1.01.01.0-1.0-1.4-1.4-1.41.4-1.4-1.5-1.3-1.61.6
Bone: cortical tissue density0.20.31.01.0-1.00.40.40.4-0.4-0.40.40.60.70.7-0.70.70.1-0.10.2-0.2
Condit. Reinf. active minus inactive responses0.40.41.31.1-1.10.60.50.6-0.6-0.60.60.70.70.7-0.70.70.3-0.00.3-0.3
Condit. Reinf. active-inactive response ratio0.20.20.80.9-0.90.20.10.3-0.3-0.30.30.40.50.5-0.50.5-0.2-0.5-0.00.0
Condit. Reinf. active responses0.30.40.91.0-1.00.80.70.8-0.8-0.80.80.50.30.3-0.30.30.30.0-0.00.0
Condit. Reinf. inactive responses0.70.81.80.9-0.91.31.31.3-1.3-1.31.30.70.30.3-0.30.30.60.6-0.10.1
Incentive salience index mean0.40.41.11.0-1.00.80.70.8-0.8-0.80.80.70.40.4-0.40.40.40.20.2-0.2
Condit. Reinf. lever presses0.30.40.80.8-0.80.90.90.9-0.9-0.90.90.60.30.3-0.30.30.50.20.1-0.1
Condit. Reinf. active minus inactive responses1.31.75.0-0.40.4-0.8-0.8-0.80.80.8-0.8-1.4-1.1-1.11.1-1.1-2.0-1.9-2.22.2
Condit. Reinf. active-inactive response ratio0.60.72.90.1-0.1-0.3-0.2-0.20.20.2-0.2-0.8-0.6-0.60.6-0.6-1.4-1.4-1.71.7
Condit. Reinf. active responses1.41.96.0-0.50.5-0.8-0.8-0.80.80.8-0.8-1.4-1.2-1.21.2-1.2-2.1-2.0-2.42.4
Condit. Reinf. inactive responses0.30.40.9-0.50.5-0.4-0.4-0.40.40.4-0.4-0.7-0.6-0.60.6-0.6-0.8-0.6-1.01.0
Condit. Reinf. lever presses0.10.10.70.2-0.20.10.10.1-0.1-0.10.1-0.2-0.1-0.10.1-0.1-0.7-0.5-0.90.9
Condit. Reinf. lever reinforcers received0.91.35.1-0.10.1-0.4-0.4-0.30.30.3-0.3-1.1-0.9-0.90.9-0.9-1.8-1.7-2.32.3
Conditioned reinforcement - actives2.94.96.2-2.22.2-2.1-2.1-2.12.12.1-2.1-2.5-2.5-2.52.5-2.5-2.0-1.9-2.12.1
Conditioned reinforcement - inactives0.40.51.3-1.11.1-0.5-0.6-0.60.60.6-0.6-0.7-1.0-1.01.0-1.00.10.2-0.10.1
Conditioned locomotion3.14.15.1-1.81.8-1.8-1.9-1.91.91.9-1.9-2.3-2.2-2.22.2-2.2-2.0-2.0-2.12.1
Patch foraging indifference point 0 sec0.30.62.3-1.01.0-0.0-0.0-0.00.00.0-0.00.1-0.3-0.30.3-0.31.31.51.3-1.3
Patch foraging indifference point AUC1.01.52.4-1.61.6-1.2-1.2-1.11.11.1-1.1-1.4-1.5-1.51.5-1.5-0.7-0.5-0.80.8
Delay disc. indifference point, 0s delay1.11.25.40.5-0.5-1.0-1.0-1.01.01.0-1.0-0.50.30.3-0.30.3-2.0-2.3-1.21.2
Delay disc. indifference point, 16s delay0.40.40.91.0-1.00.70.70.7-0.7-0.70.70.40.50.5-0.50.5-0.3-0.3-0.50.5
Delay disc. indifference point, 2s delay2.22.56.42.5-2.51.41.41.4-1.4-1.41.41.41.91.9-1.91.9-0.6-0.8-0.40.4
Delay disc. indifference point, 24s delay0.60.71.51.2-1.20.90.90.9-0.9-0.90.90.80.90.9-0.90.90.10.1-0.00.0
Delay disc. indifference point, 4s delay0.90.92.51.6-1.60.70.70.7-0.7-0.70.70.81.21.2-1.21.2-0.6-0.8-0.40.4
Delay disc. indifference point, 8s delay0.40.51.11.0-1.00.80.80.8-0.8-0.80.80.40.50.5-0.50.5-0.3-0.3-0.60.6
Indifference point function ln k0.10.10.2-0.10.10.40.40.3-0.3-0.30.3-0.0-0.4-0.40.4-0.40.30.3-0.10.1
Indifference point function log k0.10.10.2-0.10.10.40.40.3-0.3-0.30.3-0.0-0.4-0.40.4-0.40.30.3-0.10.1
Patch foraging total patch changes 0 sec0.40.83.3-1.11.10.10.10.1-0.1-0.10.10.2-0.3-0.30.3-0.31.61.81.5-1.5
Patch foraging total patch changes 12 sec0.40.51.5-1.21.2-0.7-0.7-0.70.70.7-0.7-0.5-0.6-0.50.5-0.50.40.70.6-0.6
Patch foraging total patch changes 18 sec0.40.72.0-1.41.4-0.5-0.5-0.50.50.5-0.5-0.3-0.6-0.60.6-0.61.01.21.1-1.1
Patch foraging total patch changes 24 sec0.30.52.0-1.01.00.40.40.4-0.4-0.40.4-0.1-0.6-0.60.6-0.61.11.40.5-0.5
Patch foraging total patch changes 6 sec0.50.72.3-1.51.5-0.5-0.5-0.50.50.5-0.5-0.5-0.9-0.90.9-0.90.91.20.8-0.8
Patch foraging time to switch 0 sec1.22.46.52.0-2.00.20.20.2-0.2-0.20.21.62.52.5-2.52.50.1-0.51.4-1.4
Patch foraging water rate 0 sec1.93.98.8-2.92.9-1.2-1.2-1.21.21.2-1.2-2.1-3.0-3.03.0-3.0-0.20.3-1.01.0
Patch foraging water rate 12 sec0.20.41.2-0.80.80.10.10.1-0.1-0.10.1-0.6-1.1-1.11.1-1.10.10.3-0.60.6
Patch foraging water rate 18 sec0.30.41.00.4-0.40.90.90.9-0.9-0.90.90.0-0.3-0.30.3-0.3-0.10.1-1.01.0
Patch foraging water rate 24 sec2.12.95.3-2.02.0-1.3-1.2-1.31.31.3-1.3-1.9-2.3-2.32.3-2.3-1.0-0.7-1.51.5
Patch foraging water rate 6 sec0.40.61.4-1.01.0-0.2-0.2-0.30.30.3-0.3-0.8-1.2-1.21.2-1.2-0.10.1-0.60.6
Seeking ratio, delayed vs. immediate footshock2.22.75.20.8-0.71.41.41.5-1.5-1.51.51.71.51.5-1.51.52.22.32.3-2.3
Distance traveled before self-admin0.40.51.31.1-1.10.70.70.7-0.7-0.70.70.70.80.8-0.80.80.10.00.1-0.1
Distance traveled after self-admin0.20.20.50.4-0.40.70.70.7-0.7-0.70.70.2-0.0-0.00.0-0.00.10.2-0.40.4
Extensor digitorum longus weight5.822.728.1-4.54.5-4.9-5.0-4.94.94.9-4.9-5.3-4.9-4.94.9-4.9-4.7-4.4-4.34.3
Bone: elastic displacement0.30.40.6-0.70.7-0.6-0.6-0.50.50.5-0.5-0.7-0.8-0.80.8-0.8-0.3-0.2-0.30.3
Bone: elastic work3.85.06.3-2.52.5-2.3-2.3-2.32.32.3-2.3-2.5-2.5-2.52.5-2.5-1.7-1.6-1.61.6
Bone: endosteal estimation0.71.53.7-1.91.9-1.1-1.1-1.01.01.0-1.0-1.3-1.5-1.51.5-1.5-0.40.0-0.50.5
Bone: endosteal perimeter0.61.21.7-1.31.3-0.8-0.8-0.80.80.8-0.8-1.3-1.3-1.31.3-1.3-1.0-0.6-1.31.3
Epididymis fat weight0.00.00.10.0-0.00.10.10.1-0.1-0.10.1-0.1-0.1-0.10.1-0.1-0.2-0.1-0.40.4
Delta time in closed arm before/after self-admin0.60.51.7-0.10.1-0.5-0.5-0.50.50.5-0.5-0.7-0.5-0.50.5-0.5-1.2-1.0-1.31.3
Delta time in open arm before/after self-admin4.54.45.22.0-2.02.22.22.2-2.2-2.22.22.32.12.1-2.12.12.02.01.9-1.9
Diff in mean of infusions in LGA sessions0.10.10.2-0.30.3-0.2-0.2-0.20.20.2-0.2-0.4-0.5-0.50.5-0.5-0.3-0.1-0.50.5
Delay discount exponential model param1.51.64.2-2.02.1-1.3-1.3-1.31.31.3-1.3-1.0-1.3-1.31.3-1.30.50.70.7-0.7
Extinction: sum of active levers before priming0.30.40.80.9-0.90.70.70.7-0.7-0.70.70.60.60.6-0.60.60.20.1-0.00.0
Active lever presses in extinction session 60.10.10.1-0.40.4-0.1-0.1-0.10.10.1-0.1-0.2-0.3-0.30.3-0.3-0.00.0-0.10.1
Bone: final force2.84.55.4-1.91.9-2.2-2.2-2.22.22.2-2.2-2.3-2.0-2.02.0-2.0-2.3-2.1-2.12.1
Bone: final moment2.03.34.1-1.71.7-2.0-1.9-1.81.81.8-1.8-2.0-1.7-1.71.7-1.7-2.0-1.7-1.81.8
Food consumed during 24 hour testing period0.40.51.3-1.11.1-0.6-0.6-0.70.70.7-0.7-0.5-0.8-0.80.8-0.80.50.50.5-0.5
Glucose2.23.44.92.2-2.21.92.02.0-2.0-2.02.01.92.22.2-2.22.20.81.00.6-0.6
Heart weight0.50.72.0-0.40.4-0.3-0.3-0.30.30.3-0.3-0.9-1.1-1.11.1-1.1-0.9-0.9-1.41.4
Delay discount hyperbolic model param1.31.53.8-1.92.0-1.1-1.1-1.11.11.1-1.1-0.9-1.3-1.31.3-1.30.60.80.7-0.7
Intermittent access intake day 1-15 change0.61.32.9-1.71.7-1.0-1.0-1.01.01.0-1.0-1.2-1.4-1.41.4-1.4-0.1-0.0-0.20.2
Intermittent access intake escalation0.61.22.7-1.61.7-1.0-1.0-1.01.01.0-1.0-1.1-1.4-1.41.4-1.4-0.1-0.0-0.20.2
Intermittent access intake escalation 20.10.10.6-0.40.40.10.10.1-0.1-0.10.10.1-0.2-0.20.2-0.20.70.80.6-0.6
Intermitt. access day 1 inactive lever presses0.10.30.9-0.91.0-0.4-0.4-0.50.50.5-0.5-0.4-0.7-0.70.7-0.70.30.30.3-0.3
Intermitt. access day 15 inactive lever presses0.30.52.1-0.00.0-0.4-0.5-0.40.40.4-0.40.50.80.8-0.80.80.60.31.5-1.5
Intermitt. access escalation Index0.10.20.30.5-0.50.60.60.5-0.5-0.50.50.30.20.2-0.20.2-0.0-0.0-0.30.3
Intermittent access day 1 total infusions0.30.41.01.0-1.00.90.90.8-0.8-0.80.80.50.40.4-0.40.4-0.1-0.0-0.50.5
Intermittent access day 15 total infusions0.10.10.4-0.20.20.10.10.0-0.0-0.00.0-0.4-0.6-0.60.6-0.6-0.3-0.1-0.60.6
Intermittent access terminal intake (last 3 days)0.00.00.10.1-0.10.20.20.2-0.2-0.20.2-0.1-0.2-0.20.2-0.2-0.1-0.0-0.30.3
Intermittent access total infusions0.10.10.40.6-0.60.30.20.2-0.2-0.20.20.10.20.2-0.20.2-0.5-0.5-0.60.6
Intermittent access day 1 locomotion0.40.61.51.2-1.20.80.80.8-0.8-0.80.80.60.70.7-0.70.7-0.2-0.2-0.40.4
Intermittent access day 15 total locomotion0.30.51.4-0.50.5-0.1-0.1-0.10.10.1-0.1-0.8-1.0-1.01.0-1.0-0.6-0.5-1.21.2
Intermittent access total locomotion0.20.20.50.7-0.70.50.50.5-0.5-0.50.50.10.10.1-0.10.1-0.4-0.3-0.70.7
Intermittent access standard deviation0.20.51.1-0.90.9-0.8-0.8-0.70.70.7-0.7-0.2-0.1-0.00.0-0.00.50.41.1-1.1
Left kidney weight10.147.259.7-7.37.3-7.7-7.7-7.77.77.7-7.7-7.4-6.8-6.86.8-6.8-5.6-5.6-4.44.4
Right kidney weight8.438.149.9-6.56.4-7.1-7.1-7.07.07.0-7.0-6.6-5.9-5.95.9-5.9-5.1-5.1-3.93.9
Cocaine induced anxiety0.10.20.50.7-0.70.30.20.3-0.3-0.30.30.20.40.4-0.40.4-0.5-0.5-0.50.5
Post-drug Anxiety2.93.17.52.7-2.71.11.11.2-1.2-1.21.21.82.52.6-2.62.6-0.0-0.50.5-0.5
Baseline Anxiety2.52.86.32.2-2.21.01.01.0-1.0-1.01.01.92.52.5-2.52.50.70.21.4-1.4
Tail length9.637.644.3-5.75.6-6.4-6.4-6.56.56.5-6.5-6.7-6.2-6.26.2-6.2-5.9-6.0-5.35.3
Length with tail19.183.398.2-8.88.7-9.9-9.9-9.99.99.9-9.9-9.9-9.1-9.09.0-9.0-8.5-8.5-7.37.3
Length without tail12.139.152.8-6.76.7-7.2-7.3-7.17.17.1-7.1-6.7-6.0-6.06.0-6.0-5.0-5.1-3.73.7
Times rat made contact with spout1.11.21.4-0.90.9-1.0-1.0-1.11.11.1-1.1-1.2-1.2-1.21.2-1.2-1.2-1.1-1.21.2
Lifetime Intake0.20.20.70.9-0.90.40.40.4-0.4-0.40.40.40.60.6-0.60.6-0.2-0.2-0.20.2
Liver weight, left3.65.912.7-3.53.6-2.6-2.6-2.62.62.6-2.6-2.5-2.7-2.72.7-2.7-0.5-0.3-0.20.2
Liver weight, right3.15.57.9-2.62.6-2.8-2.8-2.82.82.8-2.8-2.4-2.2-2.22.2-2.2-1.7-1.8-1.01.0
Locomotor activity2.43.78.4-1.51.5-1.2-1.2-1.11.11.1-1.1-2.2-2.3-2.32.3-2.3-2.1-1.7-2.92.9
Locomotor testing distance0.61.12.2-1.31.3-0.7-0.7-0.70.70.7-0.7-1.2-1.5-1.51.5-1.5-0.6-0.2-1.11.1
Locomotor testing rearing0.10.21.5-0.30.40.30.30.3-0.3-0.30.30.3-0.0-0.00.0-0.00.91.20.6-0.6
Locomotion in novel chamber1.62.13.0-1.51.5-1.3-1.4-1.31.31.3-1.3-1.6-1.7-1.71.7-1.7-1.0-1.0-1.21.2
Locomotion in novel chamber post-restriction1.52.44.4-1.41.4-1.1-1.2-1.01.01.0-1.0-1.8-1.9-1.91.9-1.9-1.5-1.3-2.12.1
Fecal boli incidents, locomotor time 11.52.23.0-1.21.2-1.3-1.3-1.31.31.3-1.3-1.7-1.6-1.61.6-1.6-1.6-1.5-1.71.7
Change in fecal boli incidents, locomotor task0.20.20.60.2-0.20.10.10.1-0.1-0.10.10.50.60.6-0.60.60.40.30.8-0.8
Time >=10cm from walls, locomotor time 11.81.93.71.9-1.91.31.31.3-1.3-1.31.31.41.71.7-1.71.70.30.10.4-0.4
Bouts of movement, locomotor time 11.82.02.5-1.41.4-1.4-1.4-1.41.41.4-1.4-1.6-1.6-1.61.6-1.6-1.2-1.2-1.31.3
Total resting periods, locomotor time 11.61.82.3-1.31.3-1.3-1.3-1.31.31.3-1.3-1.5-1.5-1.51.5-1.5-1.2-1.2-1.31.3
Rest time, locomotor task time 11.51.92.3-1.31.2-1.5-1.5-1.51.51.5-1.5-1.5-1.3-1.31.3-1.3-1.3-1.3-1.11.1
Distance moved, locomotor task time 10.50.71.21.0-1.01.11.11.1-1.1-1.11.10.80.70.7-0.70.70.40.3-0.00.0
Vertical activity count, locomotor time 10.10.10.60.0-0.00.30.30.3-0.3-0.30.3-0.2-0.4-0.40.4-0.4-0.2-0.2-0.80.8
Time >=10cm from walls, locomotor time 20.40.62.50.1-0.1-0.8-0.8-0.80.80.8-0.8-0.50.00.0-0.00.0-1.4-1.6-0.90.9
Bouts of movement, locomotor time 21.01.51.9-1.21.2-1.2-1.2-1.21.21.2-1.2-1.4-1.4-1.41.4-1.4-1.1-1.0-1.11.1
Total resting periods, locomotor time 20.81.41.7-1.31.3-1.2-1.2-1.21.21.2-1.2-1.3-1.3-1.31.3-1.3-0.9-0.9-0.90.9
Rest time, locomotor task time 20.20.20.30.5-0.50.50.50.5-0.5-0.50.50.50.50.5-0.50.50.40.30.4-0.4
Distance moved, locomotor task time 20.10.10.3-0.50.5-0.3-0.3-0.30.30.3-0.3-0.4-0.5-0.50.5-0.5-0.1-0.0-0.20.2
Vertical activity count, locomotor time 21.82.43.5-1.81.8-1.5-1.5-1.51.51.5-1.5-1.7-1.9-1.91.9-1.9-1.0-0.9-1.21.2
Light reinforcement 10.92.14.52.1-2.11.61.61.6-1.6-1.61.61.41.51.5-1.51.50.10.2-0.30.3
Light reinforcement 20.20.40.60.4-0.40.60.60.6-0.6-0.60.60.60.60.6-0.60.60.70.80.6-0.6
Bone: marrow area0.61.43.7-1.91.9-1.0-1.0-1.01.01.0-1.0-1.3-1.4-1.41.4-1.4-0.30.1-0.50.5
Bone: maximum diameter1.32.53.2-1.61.6-1.8-1.8-1.71.71.7-1.7-1.7-1.4-1.41.4-1.4-1.5-1.4-1.21.2
Bone: maximum force1.93.54.4-1.91.9-1.9-1.9-1.81.81.8-1.8-2.1-1.9-1.91.9-1.9-1.9-1.6-1.91.9
Bone: maximum moment1.52.63.4-1.71.7-1.6-1.6-1.51.51.5-1.5-1.8-1.6-1.61.6-1.6-1.6-1.3-1.61.6
Mean time between licks in bursts1.02.53.31.4-1.41.81.81.8-1.8-1.81.81.71.41.4-1.41.41.71.61.3-1.3
Mean num. licks in bursts0.10.10.20.5-0.50.20.10.2-0.2-0.20.20.20.40.4-0.40.4-0.4-0.4-0.30.3
Cd content in liver0.50.61.10.6-0.61.01.11.1-1.1-1.11.10.2-0.2-0.20.2-0.2-0.10.2-1.01.0
Co content in liver0.80.92.6-1.61.6-0.5-0.5-0.60.60.6-0.6-0.6-1.2-1.21.2-1.20.91.10.7-0.7
Cu content in liver0.30.30.70.2-0.20.70.70.7-0.7-0.70.70.50.50.5-0.50.50.50.80.2-0.2
Fe content in liver0.40.52.0-0.30.3-0.1-0.1-0.00.00.0-0.0-0.7-0.6-0.60.6-0.6-1.0-0.6-1.41.4
K content in liver0.10.10.20.1-0.1-0.3-0.3-0.40.40.4-0.4-0.00.20.2-0.20.2-0.4-0.5-0.10.1
Mg content in liver0.80.81.4-0.80.8-1.1-1.0-1.21.21.2-1.2-0.8-0.8-0.80.8-0.8-0.6-0.7-0.30.3
Mn content in liver0.20.20.70.2-0.20.20.20.2-0.2-0.20.20.50.40.4-0.40.40.70.50.8-0.8
Na content in liver1.11.21.8-0.80.8-1.2-1.2-1.31.31.3-1.3-1.1-0.9-0.90.9-0.9-1.1-1.3-0.70.7
Rb content in liver3.03.54.52.1-2.12.12.12.0-2.0-2.02.02.11.91.9-1.91.91.51.31.1-1.1
Se content in liver1.11.23.90.0-0.0-1.2-1.1-1.21.21.2-1.2-0.8-0.1-0.10.1-0.1-2.0-2.0-1.41.4
Sr content in liver0.40.31.1-1.01.0-0.5-0.5-0.50.50.5-0.5-0.5-0.7-0.70.7-0.70.20.20.3-0.3
Zn content in liver3.64.07.7-2.82.8-2.1-2.1-2.12.12.1-2.1-2.1-2.2-2.22.2-2.2-1.0-0.7-0.90.9
Bone: minimum diameter0.10.10.30.1-0.10.40.40.5-0.5-0.50.50.30.40.4-0.40.40.20.4-0.00.0
Time in familiar zone, hab. session 10.50.52.2-0.10.10.10.10.0-0.0-0.00.00.60.60.6-0.60.61.11.11.5-1.5
Time in novel zone, hab. session 10.60.61.6-0.20.2-0.6-0.6-0.60.60.6-0.6-0.8-0.7-0.70.7-0.7-1.1-1.3-1.11.1
Total zone transitions, hab. session 11.42.03.51.8-1.81.91.91.8-1.8-1.81.81.31.01.0-1.01.00.70.60.0-0.0
Total locomotion distance, hab. session 10.60.91.91.4-1.41.11.11.1-1.1-1.11.10.90.90.9-0.90.90.20.0-0.10.1
Locomotion velocity, hab. session 11.62.34.02.0-2.01.81.81.8-1.8-1.81.81.51.41.4-1.41.40.50.50.1-0.1
Time in familiar zone, hab. session 20.10.10.20.1-0.1-0.3-0.3-0.30.30.3-0.30.20.40.5-0.50.5-0.0-0.10.4-0.4
Time in novel zone, hab. session 20.30.30.70.6-0.60.80.80.8-0.8-0.80.80.40.10.1-0.10.10.30.3-0.20.2
Total zone transitions, hab. session 20.20.30.5-0.30.3-0.2-0.2-0.30.30.3-0.3-0.5-0.7-0.70.7-0.7-0.5-0.6-0.70.7
Total locomotion distance, hab. session 20.20.20.50.6-0.60.70.70.6-0.6-0.60.60.30.20.2-0.20.20.10.1-0.20.2
Locomotion velocity, hab. session 20.10.20.50.5-0.50.60.70.6-0.6-0.60.60.30.10.1-0.10.10.10.1-0.20.2
Novel to familiar place preference ratio0.00.00.10.3-0.30.30.30.3-0.3-0.30.30.10.10.1-0.10.1-0.10.1-0.20.2
Novelty place preference0.20.20.40.6-0.60.60.60.6-0.6-0.60.60.40.40.4-0.40.40.20.3-0.00.0
Time in novel zone, NPP test0.10.10.20.4-0.40.40.40.4-0.4-0.40.40.20.20.2-0.20.20.00.2-0.10.1
Total zone transitions, NPP test0.10.10.40.1-0.10.10.10.1-0.1-0.10.1-0.2-0.3-0.30.3-0.3-0.4-0.5-0.70.7
Total locomotion distance, NPP test0.20.30.80.9-0.90.50.50.5-0.5-0.50.50.20.20.2-0.20.2-0.6-0.7-0.90.9
Locomotion velocity, NPP test0.20.31.30.7-0.70.50.50.5-0.5-0.50.5-0.1-0.2-0.20.2-0.2-0.7-0.7-1.11.1
Intraocular pressure1.52.23.3-1.71.7-1.4-1.4-1.41.41.4-1.4-1.7-1.8-1.81.8-1.8-1.0-1.0-1.11.1
Delta distance traveled before/after self-admin0.20.20.5-0.70.70.10.10.1-0.1-0.10.1-0.3-0.7-0.70.7-0.70.40.6-0.00.0
Delta ambulatory time before/after self-admin0.40.51.30.1-0.10.90.90.9-0.9-0.90.90.60.20.2-0.20.21.11.10.6-0.6
Parametrial fat weight0.20.51.3-0.10.1-1.0-1.1-1.11.11.1-1.1-0.20.30.3-0.30.3-0.4-0.80.5-0.5
Pavlov. Cond. lever latency2.53.14.7-2.22.2-2.0-2.0-2.02.02.0-2.0-1.9-1.7-1.71.7-1.7-1.2-1.0-0.80.8
Pavlov. Cond. magazine entry latency0.30.41.2-0.20.2-0.3-0.3-0.30.30.3-0.3-0.6-0.6-0.60.6-0.6-0.9-0.8-1.11.1
Pavlov. Cond. change in total contacts0.70.72.01.4-1.40.60.60.7-0.7-0.70.70.71.01.0-1.01.0-0.4-0.6-0.30.3
Pavlov. Cond. index score0.20.20.60.8-0.80.50.50.5-0.5-0.50.50.40.40.4-0.40.4-0.2-0.3-0.30.3
Pavlov. Cond. latency score0.40.51.31.2-1.20.80.80.8-0.8-0.80.80.70.70.7-0.70.7-0.0-0.2-0.20.2
Pavlov. Cond. lever contacts2.12.54.12.0-2.01.71.81.7-1.7-1.71.71.71.61.6-1.61.60.90.70.7-0.7
Pavlov. Cond. magazine entry number0.30.31.40.1-0.10.20.10.1-0.1-0.10.10.50.50.5-0.50.50.90.81.2-1.2
Pavlov. Cond. intertrial magazine entries1.11.32.00.9-0.91.31.21.4-1.4-1.41.41.10.90.9-0.90.91.31.41.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.7-0.70.30.40.4-0.4-0.40.40.30.40.4-0.40.4-0.2-0.3-0.20.2
Pavlov. Cond. response bias0.10.10.70.2-0.20.10.10.1-0.1-0.10.1-0.2-0.2-0.20.2-0.2-0.6-0.6-0.80.8
Pavlov. Cond. lever latency0.40.61.1-1.01.1-0.9-0.9-0.90.90.9-0.9-0.4-0.6-0.60.6-0.60.50.20.8-0.8
Pavlov. Cond. magazine entry latency2.02.45.02.2-2.21.61.61.6-1.6-1.61.61.41.71.7-1.71.7-0.0-0.0-0.30.3
Pavlov. Cond. change in total contacts0.40.71.20.9-0.91.11.11.1-1.1-1.11.10.40.40.4-0.40.4-0.20.0-0.90.9
Pavlov. Cond. index score1.31.73.11.8-1.81.61.61.6-1.6-1.61.61.11.11.1-1.11.1-0.00.1-0.60.6
Pavlov. Cond. latency score1.21.53.01.7-1.71.41.41.5-1.5-1.51.51.01.21.1-1.11.1-0.10.1-0.60.6
Pavlov. Cond. lever contacts0.60.81.61.3-1.31.01.01.0-1.0-1.01.00.50.70.7-0.70.7-0.5-0.3-0.90.9
Pavlov. Cond. magazine entry number1.82.24.0-2.02.0-1.7-1.7-1.81.81.8-1.8-1.4-1.5-1.51.5-1.5-0.3-0.40.2-0.2
Pavlov. Cond. intertrial magazine entries0.50.71.2-1.11.1-0.7-0.7-0.70.70.7-0.7-1.0-1.1-1.11.1-1.1-0.5-0.5-0.60.6
Pavlov. Cond. lever-magazine prob. diff.1.41.93.41.8-1.91.61.61.7-1.7-1.71.71.11.21.2-1.21.2-0.10.1-0.70.7
Pavlov. Cond. response bias1.31.83.41.8-1.81.61.61.7-1.7-1.71.71.01.11.1-1.11.1-0.3-0.1-0.90.9
Time in closed arm before self-admin1.72.23.9-1.81.8-1.2-1.2-1.21.21.2-1.2-1.7-2.0-2.02.0-2.0-0.9-0.7-1.21.2
Time in closed arm after self-admin2.62.84.4-1.61.6-1.2-1.2-1.21.21.2-1.2-1.9-2.1-2.12.1-2.1-1.5-1.2-2.02.0
Time in open arm before self-admin0.10.10.60.4-0.40.10.10.1-0.1-0.10.1-0.10.00.0-0.00.0-0.7-0.7-0.80.8
Time in open arm after self-admin1.92.12.71.6-1.61.41.41.4-1.4-1.41.41.61.61.6-1.61.61.11.01.2-1.2
Bone: periosteal estimation1.32.83.7-1.81.8-1.7-1.7-1.61.61.6-1.6-1.9-1.7-1.71.7-1.7-1.7-1.4-1.71.7
Bone: periosteal perimeter0.50.82.9-0.50.5-0.5-0.6-0.40.40.4-0.4-1.0-0.7-0.70.7-0.7-1.5-1.2-1.71.7
Bone: post-yield work0.10.10.3-0.60.6-0.2-0.2-0.20.20.2-0.2-0.4-0.4-0.40.4-0.4-0.3-0.0-0.50.5
Progressive ratio test 1 active lever presses1.41.82.1-1.11.1-1.3-1.3-1.31.31.3-1.3-1.5-1.3-1.31.3-1.3-1.4-1.4-1.41.4
Progressive ratio test 1 breakpoint1.41.72.1-1.11.1-1.3-1.3-1.31.31.3-1.3-1.4-1.3-1.31.3-1.3-1.4-1.4-1.41.4
Progressive ratio test 1 inactive lever presses0.91.32.5-1.61.6-1.0-1.0-1.01.01.0-1.0-1.2-1.5-1.51.5-1.5-0.4-0.3-0.60.6
Progressive ratio test 2 active lever presses1.31.62.5-1.21.2-1.0-1.0-1.01.01.0-1.0-1.4-1.6-1.61.6-1.6-1.1-0.9-1.41.4
Progressive ratio test 2 breakpoint1.21.42.3-1.11.1-0.9-0.9-0.90.90.9-0.9-1.3-1.5-1.51.5-1.5-1.0-0.9-1.31.3
Progressive ratio test 2 inactive lever presses2.64.16.9-2.62.6-1.8-1.9-1.91.91.9-1.9-2.2-2.5-2.52.5-2.5-1.0-0.8-1.21.2
Incentive Sensitization - Responses0.00.00.1-0.00.00.30.20.2-0.2-0.20.20.1-0.2-0.20.2-0.20.30.30.0-0.0
Incentive Sensitization - Breakpoint0.10.10.20.1-0.10.40.40.3-0.3-0.30.30.2-0.1-0.10.1-0.10.40.40.1-0.1
Sum of active levers in priming session hrs 5-60.10.10.20.2-0.2-0.4-0.4-0.40.40.4-0.40.10.40.4-0.40.4-0.3-0.40.2-0.2
Progressive ratio0.50.81.30.8-0.80.60.60.7-0.7-0.70.70.91.21.2-1.21.20.70.70.9-0.9
Food seeking constrained by brief footshock1.62.06.30.3-0.20.90.90.9-0.9-0.90.91.30.90.9-0.90.92.42.42.5-2.5
Seeking ratio, punishment vs. effort0.60.81.5-1.11.1-0.7-0.7-0.90.90.9-0.9-0.8-1.2-1.21.2-1.2-0.1-0.2-0.20.2
Retroperitoneal fat weight0.10.51.11.0-1.0-0.3-0.4-0.40.40.4-0.40.41.01.1-1.11.1-0.5-0.90.3-0.3
Reaction time number correct0.40.72.0-1.41.4-0.4-0.4-0.30.30.3-0.3-0.8-1.2-1.21.2-1.20.20.5-0.30.3
Reaction time mean minus median0.51.45.91.2-1.20.20.30.3-0.3-0.30.3-0.40.10.1-0.10.1-2.0-2.0-2.42.4
Reaction time mean minus median AUC0.51.22.01.4-1.41.31.31.3-1.3-1.31.30.60.60.6-0.60.6-0.5-0.3-1.21.2
Reaction time num false alarms0.40.51.01.0-1.00.90.90.9-0.9-0.90.90.30.10.1-0.10.1-0.4-0.2-1.01.0
Reaction time num false alarms AUC0.20.30.80.6-0.60.60.60.6-0.6-0.60.60.1-0.0-0.00.0-0.0-0.4-0.2-0.90.9
Reaction time trials correct on left0.40.72.0-1.41.4-0.4-0.4-0.30.30.3-0.3-0.8-1.2-1.21.2-1.20.20.5-0.30.3
Reaction time trials on left0.30.61.8-1.31.3-0.3-0.3-0.30.30.3-0.3-0.8-1.2-1.21.2-1.20.20.5-0.30.3
Reaction time mean2.33.78.32.9-2.91.91.91.9-1.9-1.91.91.92.22.2-2.22.20.20.10.1-0.1
Reaction time mean AUC2.53.98.42.9-2.92.12.12.1-2.1-2.12.12.02.22.2-2.22.20.40.20.1-0.1
Median of all reaction times3.65.19.13.0-3.02.22.22.2-2.2-2.22.22.42.72.7-2.72.71.00.81.0-1.0
Reaction time omissions0.60.92.21.5-1.50.90.91.0-1.0-1.01.00.81.11.1-1.11.1-0.3-0.2-0.40.4
Reaction time false alarm rate0.30.51.51.2-1.20.70.60.6-0.6-0.60.60.40.40.4-0.40.4-0.6-0.6-0.80.8
Reaction time premature initiation rate0.20.21.00.5-0.60.20.20.2-0.2-0.20.2-0.10.10.1-0.10.1-0.8-0.8-1.01.0
Reaction time premature initiations0.10.20.9-0.10.10.10.10.1-0.1-0.10.1-0.4-0.4-0.40.4-0.4-0.6-0.4-1.01.0
Std. dev. reaction times0.71.43.61.9-1.91.01.01.0-1.0-1.01.00.71.01.0-1.01.0-1.0-1.1-1.21.2
Reaction time trials completed0.30.61.8-1.31.3-0.3-0.3-0.30.30.3-0.3-0.8-1.2-1.21.2-1.20.20.5-0.30.3
Reaction time trials AUC0.20.51.3-1.11.1-0.1-0.1-0.00.00.0-0.0-0.6-1.0-1.01.0-1.00.30.7-0.20.2
Run reversals in cocaine runway, females1.11.11.50.9-0.91.00.91.0-1.0-1.01.01.11.11.1-1.11.11.11.11.2-1.2
Run reversals in cocaine runway, males0.20.20.6-0.20.20.60.60.6-0.6-0.60.60.1-0.4-0.40.4-0.40.60.8-0.00.0
Latency to leave start box in cocaine runway0.00.10.10.3-0.3-0.1-0.1-0.20.20.2-0.20.10.30.3-0.30.3-0.2-0.30.1-0.1
Latency to leave start box in cocaine runway, F0.30.41.0-0.40.4-0.9-0.9-1.01.01.0-1.0-0.4-0.2-0.20.2-0.2-0.4-0.60.2-0.2
Latency to leave start box in cocaine runway, M0.30.30.50.7-0.70.70.70.7-0.7-0.70.70.50.40.4-0.40.40.20.2-0.00.0
Std. dev. time between licks in bursts0.20.20.8-0.20.20.10.10.1-0.1-0.10.1-0.4-0.6-0.60.6-0.6-0.5-0.2-0.90.9
Total sessions with >9 infusions0.10.10.30.3-0.3-0.0-0.1-0.10.10.1-0.10.40.50.5-0.50.50.20.00.6-0.6
Short access day 1 total inactive lever presses0.40.50.9-0.90.9-0.8-0.8-0.90.90.9-0.9-0.4-0.3-0.30.3-0.30.2-0.00.7-0.7
Short access day 10 total inactive lever presses1.23.05.8-2.42.4-2.2-2.2-2.22.22.2-2.2-1.4-1.3-1.31.3-1.3-0.1-0.30.8-0.8
Short access day 1 total infusions0.91.22.01.0-1.00.70.70.7-0.7-0.70.71.21.41.4-1.41.41.11.01.4-1.4
Short access day 10 total infusions0.30.40.50.7-0.70.60.60.5-0.5-0.50.50.70.70.7-0.70.70.60.50.6-0.6
Short access total infusions0.70.91.91.2-1.20.50.50.5-0.5-0.50.51.11.41.4-1.41.40.50.31.0-1.0
Short access day 1 locomotion0.30.41.21.1-1.10.50.50.5-0.5-0.50.50.40.60.6-0.60.6-0.5-0.6-0.60.6
Short access day 10 total locomotion0.10.10.3-0.50.5-0.3-0.4-0.30.30.3-0.3-0.1-0.1-0.10.1-0.10.40.40.5-0.5
Short access total locomotion0.40.51.21.1-1.10.60.60.5-0.5-0.50.50.81.01.0-1.01.00.1-0.00.3-0.3
One hour access (0.3 mA shock)1.11.23.3-1.41.4-0.2-0.2-0.20.20.2-0.2-1.2-1.8-1.81.8-1.8-0.10.3-1.11.1
Compulsive drug intake2.22.63.51.4-1.41.81.91.8-1.8-1.81.81.71.41.4-1.41.41.71.81.4-1.4
One hour access (shock baseline)1.72.64.4-1.41.4-1.1-1.2-1.11.11.1-1.1-1.8-1.9-1.91.9-1.9-1.6-1.4-2.12.1
Social response proportion6.06.811.0-1.71.7-2.5-2.4-2.52.52.5-2.5-2.8-2.4-2.42.4-2.4-3.3-3.3-3.23.2
Social responses1.92.54.8-1.31.3-1.1-1.1-1.11.11.1-1.1-1.8-1.8-1.81.8-1.8-1.7-1.4-2.22.2
Social time2.63.55.62.4-2.42.32.32.3-2.3-2.32.31.91.81.8-1.81.80.90.90.3-0.3
Soleus weight1.54.45.7-2.42.4-2.0-2.0-2.02.02.0-2.0-2.4-2.4-2.42.4-2.4-1.7-1.6-1.61.6
Bone: stiffness0.60.93.1-0.50.5-0.6-0.6-0.50.50.5-0.5-1.0-0.9-0.90.9-0.9-1.4-1.1-1.81.8
Tibialis anterior weight7.625.931.1-4.64.6-5.4-5.4-5.45.45.4-5.4-5.6-4.9-4.94.9-4.9-5.3-5.1-4.74.7
Time to tail flick, vehicle, before self-admin0.70.82.41.5-1.60.50.50.5-0.5-0.50.50.71.21.2-1.21.2-0.5-0.7-0.10.1
Time to tail flick, vehicle, after self-admin0.10.10.40.3-0.30.20.20.2-0.2-0.20.2-0.1-0.1-0.10.1-0.1-0.4-0.1-0.60.6
Time to tail flick, test, before self-admin1.41.41.9-1.41.4-1.2-1.2-1.21.21.2-1.2-1.3-1.3-1.31.3-1.3-0.9-1.0-0.90.9
Time to tail flick, test, after self-admin0.20.20.50.7-0.70.10.10.1-0.1-0.10.10.40.70.7-0.70.7-0.2-0.30.1-0.1
Delta time to tail flick, vehicle, before/after SA0.20.20.8-0.10.10.60.60.6-0.6-0.60.60.2-0.2-0.20.2-0.20.50.9-0.00.0
Delta time to tail flick, test, before/after SA1.21.21.61.2-1.21.01.01.0-1.0-1.01.01.31.31.3-1.31.31.01.01.1-1.1
Tibia length4.412.218.0-3.53.5-4.2-4.2-4.14.14.1-4.1-3.7-3.1-3.03.0-3.0-3.2-3.0-2.22.2
Ambulatory time before self-admin0.10.20.40.7-0.70.30.30.3-0.3-0.30.30.20.20.2-0.20.2-0.4-0.4-0.50.5
Ambulatory time after self-admin0.40.40.90.6-0.60.90.90.9-0.9-0.90.90.50.30.3-0.30.30.40.4-0.10.1
Bone: tissue strength0.40.41.5-0.70.8-0.2-0.2-0.20.20.2-0.20.1-0.3-0.20.2-0.21.00.91.2-1.2
Total heroin consumption3.54.16.82.6-2.62.42.42.4-2.4-2.42.42.01.91.9-1.91.90.91.10.5-0.5
Bone: trabecular number3.35.47.2-2.72.7-2.6-2.5-2.62.62.6-2.6-2.5-2.4-2.42.4-2.4-1.6-1.5-1.21.2
Bone: trabecular spacing3.44.45.32.1-2.12.22.22.2-2.2-2.22.22.32.22.2-2.22.21.91.81.7-1.7
Bone: trabecular thickness3.74.65.6-2.42.3-2.4-2.3-2.32.32.3-2.3-2.3-2.2-2.22.2-2.2-1.8-1.6-1.51.5
Bone: trabecular tissue density0.91.45.61.3-1.3-0.2-0.2-0.20.20.2-0.2-0.40.00.0-0.00.0-2.1-2.4-2.12.1
Water consumed over 24 hours2.93.95.6-2.42.4-2.0-2.0-2.12.12.1-2.1-2.1-2.3-2.32.3-2.3-1.1-0.9-0.90.9
Number of responses in last shaping day0.20.20.40.5-0.50.30.30.3-0.3-0.30.30.50.60.6-0.60.60.30.20.4-0.4