Hub : Genes

Armc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Armc1 0.04 0.03 1.8e-03 0.01 0.01 0 0 7.3e-02 3.6e-02 2.7e-01 1.6e-01
2 NAcc gene expression Armc1 0.05 0.03 2.1e-07 0.04 0.04 0.02 0.04 2.3e-06 1.8e-06 2.8e-04 3.1e-06
3 LHb isoform ratio XM_039101979.2 0.2 0.12 1.0e-02 0.02 0.04 0.02 0.02 9.2e-02 5.2e-02 1.1e-01 1.0e-01
4 LHb gene expression Armc1 0.32 0.15 4.4e-04 0.09 0.11 0.08 0.09 3.1e-03 1.4e-03 5.2e-03 4.0e-03
5 LHb alternative TSS NM_001106425.2 0.28 0.13 1.1e-03 -0.01 0.03 0 0.01 7.2e-01 8.4e-02 3.3e-01 1.7e-01
6 LHb alternative TSS XM_039101979.2 0.27 0.13 1.4e-03 -0.01 0.03 -0.01 0 8.2e-01 8.6e-02 9.3e-01 2.6e-01
7 Brain gene expression Armc1 0.04 0.03 1.6e-04 0.03 0.04 0.04 0.03 4.6e-04 2.5e-04 2.3e-04 3.9e-04
8 Brain mRNA stability Armc1 0.05 0.03 1.9e-04 0.03 0.02 0.01 0.02 3.8e-04 3.8e-03 1.8e-02 3.2e-03
9 PL gene expression Armc1 0.04 0.02 2.4e-05 0.04 0.04 0.02 0.03 8.7e-05 7.8e-05 1.4e-03 1.4e-04
10 BLA gene expression Armc1 0.14 0.08 6.3e-06 0.05 0.06 0.06 0.05 1.3e-03 5.5e-04 3.8e-04 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.22.33.01.51.61.61.4-1.71.7-1.51.31.5-1.1
Area under the delay curve0.10.10.3-0.3-0.4-0.3-0.4-0.10.10.5-0.1-0.20.1
BMI with tail2.58.811.5-3.1-3.4-3.3-3.33.0-3.02.9-2.9-2.61.8
BMI without tail1.26.48.3-2.7-2.9-2.7-2.72.3-2.32.7-2.3-2.52.2
Body weight2.511.013.6-3.2-3.7-3.5-3.23.5-3.43.4-3.2-3.52.3
Weight adjusted by age0.10.31.0-0.4-0.6-0.4-0.20.5-0.40.6-0.5-1.00.5
Bone surface0.00.00.10.10.20.10.1-0.20.2-0.20.30.3-0.2
Bone volume0.00.00.00.10.20.20.2-0.20.2-0.20.10.2-0.0
Breakpoint value in progressive ratio session0.10.31.2-0.6-0.3-0.4-0.50.2-0.30.2-0.5-0.11.1
Number of licking bursts0.61.82.8-1.3-1.4-1.3-1.11.4-1.41.1-1.7-1.61.2
Context. condit. distance diff. score0.10.20.80.1-0.4-0.10.10.00.10.6-0.5-0.9-0.1
Locomotion velocity, session 10.20.20.7-0.5-0.6-0.5-0.50.1-0.10.8-0.3-0.40.4
Locomotion distance, session 10.10.20.4-0.2-0.2-0.4-0.70.4-0.5-0.20.30.6-0.6
Locomotion velocity, session 22.02.44.0-1.8-1.8-1.7-1.91.2-1.22.0-1.2-1.01.3
Locomotion distance, session 20.20.20.7-0.2-0.3-0.5-0.60.4-0.5-0.20.20.5-0.9
Locomotion velocity, session 31.21.31.8-1.2-1.4-1.3-1.31.0-1.01.2-1.3-1.10.7
Locomotion distance, session 30.70.81.5-0.9-1.1-0.9-0.90.5-0.51.0-1.2-1.00.8
Stereotopy head waving bouts, day 30.30.30.60.60.60.60.7-0.40.5-0.70.50.2-0.4
Stereotopy head waving duration, day 30.40.51.10.60.90.70.7-0.30.3-1.00.70.8-0.5
Locomotion velocity, session 72.52.73.91.91.81.71.7-1.11.2-1.81.71.4-2.0
Locomotion distance, session 72.73.44.82.12.22.12.2-1.61.7-1.91.51.5-1.6
Stereotopy head waving bouts, day 70.50.61.0-0.8-1.0-0.9-0.80.6-0.60.9-0.7-1.00.6
Stereotopy head waving duration, day 70.30.40.5-0.7-0.7-0.6-0.60.4-0.40.6-0.6-0.60.7
Locomotion velocity, session 81.11.32.5-1.1-1.4-1.3-1.40.9-0.91.6-1.0-0.90.5
Locomotion distance, session 81.21.72.4-1.2-1.6-1.5-1.41.3-1.21.5-1.3-1.30.5
Degree of sensitization distance4.34.66.72.12.62.32.2-1.61.6-2.52.32.3-1.7
Degree of sensitization stereotypy2.02.23.3-1.4-1.8-1.6-1.51.1-1.11.8-1.5-1.71.2
Conditioned locomotion1.92.33.41.61.41.41.2-1.41.4-1.41.71.6-1.8
Cocaine response after cond. corrected0.10.20.60.30.60.60.8-0.40.4-0.10.10.00.6
Cocaine response after cond. not corrected0.20.20.60.30.60.60.8-0.40.4-0.1-0.0-0.00.6
Cocaine response before conditioning0.20.20.50.40.50.30.3-0.20.1-0.60.50.6-0.7
Saline control response0.71.01.9-1.1-1.0-1.2-1.11.4-1.40.5-0.6-0.70.5
Bone: connectivity density1.82.94.71.51.81.61.3-2.11.9-1.71.72.2-1.0
Bone: cortical apparent density0.50.81.9-0.8-1.0-0.7-0.70.2-0.21.4-0.9-1.01.3
Bone: cortical area0.40.72.3-0.2-0.8-0.6-0.21.2-1.10.8-0.6-1.5-0.4
Bone: cortical porosity0.60.72.50.70.70.50.40.0-0.0-1.20.80.9-1.6
Bone: cortical porosity0.40.42.30.60.40.30.30.00.0-0.70.60.5-1.5
Bone: cortical thickness0.40.73.31.20.50.71.1-0.00.2-0.30.7-0.5-1.8
Bone: cortical thickness0.30.30.5-0.3-0.7-0.6-0.50.7-0.60.7-0.0-0.7-0.5
Bone: cortical tissue density0.71.12.4-1.0-1.1-0.9-0.90.2-0.21.5-1.1-1.11.6
Condit. Reinf. active minus inactive responses0.20.20.5-0.4-0.3-0.5-0.60.7-0.7-0.20.30.3-0.4
Condit. Reinf. active-inactive response ratio0.10.10.3-0.10.1-0.1-0.20.2-0.3-0.40.40.5-0.3
Condit. Reinf. active responses0.20.30.7-0.6-0.5-0.7-0.80.5-0.60.20.40.1-0.2
Condit. Reinf. inactive responses0.50.61.0-0.9-0.9-0.9-1.00.7-0.70.8-0.2-0.50.6
Incentive salience index mean0.30.40.7-0.7-0.6-0.8-0.80.8-0.90.2-0.1-0.20.2
Condit. Reinf. lever presses0.40.61.2-1.0-0.8-0.8-0.90.4-0.50.7-0.5-0.51.1
Condit. Reinf. active minus inactive responses0.10.10.30.0-0.4-0.3-0.30.3-0.30.2-0.3-0.4-0.6
Condit. Reinf. active-inactive response ratio0.00.10.20.2-0.3-0.1-0.2-0.20.20.2-0.2-0.1-0.4
Condit. Reinf. active responses0.10.20.70.1-0.1-0.2-0.10.6-0.6-0.30.0-0.1-0.8
Condit. Reinf. inactive responses0.10.21.0-0.1-0.1-0.20.01.0-0.9-0.20.0-0.4-0.3
Condit. Reinf. lever presses0.10.20.80.40.50.40.50.0-0.0-0.90.30.3-0.4
Condit. Reinf. lever reinforcers received0.10.10.60.1-0.1-0.2-0.10.6-0.6-0.20.0-0.1-0.8
Conditioned reinforcement - actives0.10.20.60.40.50.40.3-0.40.3-0.80.50.7-0.3
Conditioned reinforcement - inactives0.00.10.4-0.10.30.30.2-0.50.4-0.20.10.20.6
Conditioned locomotion0.20.31.6-0.3-0.3-0.2-0.2-0.10.10.3-0.7-0.51.3
Patch foraging indifference point 0 sec0.10.41.2-0.3-0.4-0.10.1-0.10.10.7-0.8-1.11.1
Patch foraging indifference point AUC0.10.31.20.40.20.1-0.1-0.50.4-0.00.80.8-1.1
Delay disc. indifference point, 0s delay0.10.10.30.1-0.3-0.3-0.20.4-0.30.2-0.0-0.3-0.5
Delay disc. indifference point, 16s delay0.30.40.80.60.40.40.2-0.70.7-0.40.90.8-0.8
Delay disc. indifference point, 2s delay0.10.10.3-0.0-0.2-0.00.0-0.20.20.5-0.3-0.50.1
Delay disc. indifference point, 24s delay1.11.72.21.31.21.31.2-1.51.5-1.11.51.1-1.3
Delay disc. indifference point, 4s delay1.92.03.2-1.6-1.6-1.6-1.81.0-1.11.5-1.3-0.91.3
Delay disc. indifference point, 8s delay0.10.10.3-0.4-0.4-0.4-0.5-0.10.00.5-0.2-0.10.5
Indifference point function ln k0.41.24.8-1.2-0.8-0.7-0.60.4-0.40.9-1.4-1.02.2
Indifference point function log k0.41.24.8-1.2-0.8-0.7-0.60.4-0.40.9-1.4-1.02.2
Patch foraging total patch changes 0 sec0.20.72.3-0.6-0.7-0.4-0.20.1-0.11.0-1.1-1.31.5
Patch foraging total patch changes 12 sec0.00.00.20.3-0.00.10.1-0.20.30.10.2-0.1-0.4
Patch foraging total patch changes 18 sec0.00.10.2-0.2-0.5-0.4-0.50.2-0.20.40.2-0.2-0.2
Patch foraging total patch changes 24 sec0.10.20.60.40.40.40.2-0.70.6-0.10.80.6-0.4
Patch foraging total patch changes 6 sec0.40.60.9-0.9-0.9-0.9-0.90.4-0.51.0-0.7-0.70.9
Patch foraging time to switch 0 sec0.00.10.2-0.1-0.1-0.2-0.10.5-0.4-0.1-0.2-0.00.1
Patch foraging water rate 0 sec0.10.30.9-0.3-0.4-0.2-0.3-0.50.40.9-0.5-0.40.8
Patch foraging water rate 12 sec0.10.51.10.60.70.50.4-0.40.4-0.80.90.9-1.1
Patch foraging water rate 18 sec0.10.10.30.30.40.40.3-0.30.3-0.40.60.5-0.3
Patch foraging water rate 24 sec0.30.40.90.60.50.60.4-1.00.9-0.21.00.7-0.5
Patch foraging water rate 6 sec0.40.72.4-0.7-0.6-0.4-0.30.3-0.30.9-1.0-1.11.5
Seeking ratio, delayed vs. immediate footshock3.24.66.92.42.42.62.6-2.42.5-1.71.81.4-0.9
Distance traveled before self-admin3.47.48.8-2.7-3.0-2.9-2.62.8-2.82.7-2.8-2.82.1
Distance traveled after self-admin5.29.111.1-3.1-3.0-2.9-2.62.9-2.83.0-3.3-3.33.2
Extensor digitorum longus weight6.124.331.0-5.4-5.6-5.4-5.44.5-4.55.3-4.5-4.44.2
Bone: elastic displacement2.53.24.32.01.61.81.7-2.12.1-1.51.91.4-1.7
Bone: elastic work0.91.21.91.21.01.21.2-1.31.4-0.81.30.6-0.8
Bone: endosteal estimation1.94.77.2-2.4-2.2-2.4-2.42.7-2.71.6-2.0-1.41.5
Bone: endosteal perimeter1.53.75.4-1.8-1.8-1.7-1.32.2-2.11.7-2.3-2.31.7
Epididymis fat weight1.47.010.4-2.5-2.9-2.6-2.22.6-2.53.2-2.6-3.12.0
Delta time in closed arm before/after self-admin0.20.20.70.30.30.2-0.0-0.20.2-0.70.40.8-0.7
Delta time in open arm before/after self-admin0.10.10.40.30.10.30.6-0.20.30.3-0.4-0.60.2
Diff in mean of infusions in LGA sessions0.10.20.40.30.40.30.2-0.40.3-0.60.50.6-0.2
Delay discount exponential model param0.10.10.20.30.40.30.40.1-0.1-0.50.20.2-0.2
Extinction: sum of active levers before priming0.10.10.20.40.40.40.4-0.40.4-0.30.00.3-0.1
Active lever presses in extinction session 62.12.14.8-1.4-1.4-1.6-1.52.2-2.10.7-1.2-0.90.2
Bone: final force1.32.14.5-1.3-1.5-1.6-1.42.1-2.11.1-1.0-1.30.1
Bone: final moment1.22.04.5-1.2-1.4-1.5-1.32.1-2.01.0-0.9-1.30.0
Food consumed during 24 hour testing period2.95.97.3-2.7-2.6-2.7-2.62.5-2.62.1-2.2-2.02.0
Glucose0.71.12.1-1.0-1.1-1.2-1.11.5-1.40.6-1.0-0.90.1
Heart weight0.40.61.3-0.9-0.9-0.8-0.80.3-0.30.9-0.5-0.71.1
Delay discount hyperbolic model param0.10.20.40.40.60.50.5-0.10.1-0.60.40.4-0.3
Intermittent access intake day 1-15 change0.10.41.0-0.7-0.7-0.8-1.00.5-0.60.5-0.40.10.2
Intermittent access intake escalation0.10.30.9-0.7-0.7-0.8-1.00.5-0.50.5-0.40.00.3
Intermittent access intake escalation 20.20.30.7-0.6-0.6-0.7-0.80.6-0.60.5-0.5-0.00.1
Intermitt. access day 1 inactive lever presses0.10.71.5-1.2-0.8-1.0-1.20.9-1.10.5-0.30.00.4
Intermitt. access day 15 inactive lever presses0.10.31.4-0.00.30.0-0.3-0.20.0-0.60.31.2-0.7
Intermitt. access escalation Index0.10.40.90.20.90.70.6-0.40.3-0.90.80.90.5
Intermittent access day 1 total infusions0.10.20.90.00.20.1-0.2-0.40.3-0.40.90.8-0.0
Intermittent access day 15 total infusions0.20.41.9-0.10.1-0.2-0.6-0.30.1-0.51.01.4-0.6
Intermittent access terminal intake (last 3 days)0.30.62.3-0.8-0.6-1.0-1.50.3-0.5-0.00.31.1-0.2
Intermittent access total infusions0.50.62.8-0.00.2-0.1-0.6-0.50.3-0.71.31.7-0.5
Intermittent access day 1 locomotion0.00.10.2-0.1-0.4-0.3-0.3-0.10.10.4-0.1-0.30.3
Intermittent access day 15 total locomotion0.10.30.9-0.5-0.6-0.5-0.60.2-0.20.5-0.7-0.41.0
Intermittent access total locomotion0.20.20.8-0.4-0.5-0.4-0.40.0-0.10.5-0.5-0.30.9
Intermittent access standard deviation0.10.61.6-0.9-0.8-1.0-1.20.8-0.80.5-0.30.1-0.1
Left kidney weight0.10.72.0-0.6-0.9-0.6-0.40.2-0.21.0-0.8-1.41.3
Right kidney weight0.32.35.2-1.3-1.8-1.4-1.11.3-1.21.7-1.5-2.31.4
Cocaine induced anxiety0.00.10.60.2-0.0-0.1-0.00.3-0.3-0.3-0.00.0-0.8
Post-drug Anxiety0.20.21.20.40.30.10.10.3-0.3-0.60.30.6-1.1
Baseline Anxiety0.10.10.4-0.5-0.3-0.3-0.40.2-0.20.4-0.3-0.00.6
Tail length0.20.82.2-0.8-0.9-0.7-0.40.7-0.61.1-0.7-1.51.3
Length with tail0.73.25.0-1.6-1.8-1.7-1.32.0-1.91.7-1.8-2.21.6
Length without tail0.62.94.1-1.5-1.8-1.7-1.41.9-1.81.8-1.9-2.01.0
Times rat made contact with spout4.04.66.9-2.0-2.0-1.9-1.42.4-2.31.9-2.6-2.62.0
Lifetime Intake0.50.62.50.00.2-0.1-0.6-0.50.3-0.61.31.6-0.5
Liver weight, left1.22.14.0-1.5-1.5-1.7-1.62.0-2.00.8-1.2-1.00.4
Liver weight, right4.88.49.9-3.1-2.8-2.9-2.73.1-3.12.8-2.7-2.62.9
Locomotor activity0.71.01.7-1.1-1.1-1.1-1.11.3-1.30.7-0.8-0.90.5
Locomotor testing distance0.61.42.7-1.1-1.2-1.3-1.01.6-1.60.9-1.0-1.30.4
Locomotor testing rearing0.10.20.60.20.2-0.00.20.8-0.7-0.30.3-0.1-0.8
Locomotion in novel chamber0.30.30.6-0.4-0.6-0.6-0.40.7-0.60.6-0.8-0.80.2
Locomotion in novel chamber post-restriction0.20.61.70.60.70.50.3-0.50.4-1.00.81.3-1.2
Fecal boli incidents, locomotor time 10.30.71.7-0.20.1-0.5-0.71.0-1.0-0.80.61.2-1.3
Change in fecal boli incidents, locomotor task1.81.94.11.91.31.72.0-1.51.7-0.80.7-0.1-0.7
Time >=10cm from walls, locomotor time 10.20.30.40.60.70.60.7-0.20.2-0.70.60.4-0.6
Bouts of movement, locomotor time 10.30.41.10.50.50.50.2-1.11.0-0.40.60.9-0.2
Total resting periods, locomotor time 10.50.51.50.50.60.60.3-1.21.1-0.40.71.0-0.1
Rest time, locomotor task time 10.50.82.3-1.0-0.8-1.2-1.50.9-1.00.3-0.20.60.0
Distance moved, locomotor task time 10.20.41.30.20.30.51.00.10.00.0-0.7-1.11.1
Vertical activity count, locomotor time 10.10.83.1-0.4-0.20.10.50.4-0.20.6-1.2-1.51.8
Time >=10cm from walls, locomotor time 20.20.61.31.00.80.80.9-0.30.4-0.90.50.4-1.1
Bouts of movement, locomotor time 20.10.41.40.40.30.40.1-1.21.1-0.10.70.8-0.1
Total resting periods, locomotor time 20.10.31.10.20.10.2-0.1-1.11.00.00.70.7-0.1
Rest time, locomotor task time 20.30.41.9-0.5-0.2-0.6-1.10.2-0.4-0.40.41.40.0
Distance moved, locomotor task time 20.30.41.50.70.80.91.2-0.20.3-0.60.1-0.3-0.2
Vertical activity count, locomotor time 20.51.12.7-1.2-0.7-0.8-0.71.1-1.10.7-1.3-0.91.6
Light reinforcement 10.21.01.8-0.9-1.1-0.9-0.80.8-0.81.3-0.8-1.30.9
Light reinforcement 21.73.810.0-1.5-1.7-1.1-0.51.1-1.02.6-2.2-3.22.8
Bone: marrow area1.94.77.2-2.4-2.1-2.4-2.42.6-2.71.6-2.0-1.41.5
Bone: maximum diameter0.71.53.3-0.9-1.2-1.0-0.61.7-1.51.1-1.2-1.80.5
Bone: maximum force1.53.06.3-1.7-1.7-1.9-1.82.5-2.51.2-1.3-1.20.4
Bone: maximum moment1.42.76.1-1.6-1.6-1.8-1.72.5-2.41.0-1.2-1.20.2
Mean time between licks in bursts0.10.91.6-1.3-0.8-1.0-1.20.7-0.90.9-1.0-0.11.1
Mean num. licks in bursts0.00.00.10.10.20.10.20.2-0.2-0.10.10.1-0.2
Cd content in liver1.82.03.7-1.6-1.5-1.8-1.91.7-1.80.9-1.2-0.50.6
Co content in liver1.41.73.1-1.3-1.1-1.2-0.91.8-1.70.9-1.5-1.30.8
Cu content in liver0.20.20.50.60.60.60.7-0.20.3-0.6-0.10.2-0.3
Fe content in liver0.20.21.20.50.20.20.40.4-0.3-0.40.2-0.1-1.1
K content in liver1.01.01.51.01.21.21.2-1.11.1-0.91.00.7-0.4
Mg content in liver0.70.81.50.91.01.11.1-1.21.2-0.70.50.6-0.0
Mn content in liver0.00.00.1-0.0-0.00.0-0.1-0.30.30.1-0.00.1-0.1
Na content in liver0.30.31.4-0.2-0.5-0.20.00.2-0.10.8-0.6-1.20.3
Rb content in liver0.91.02.01.21.11.01.1-0.20.3-1.40.90.9-1.3
Se content in liver0.10.10.90.40.20.20.40.1-0.0-0.2-0.0-0.1-0.9
Sr content in liver1.21.12.10.71.00.90.6-1.41.2-1.11.01.4-0.6
Zn content in liver0.20.20.30.30.60.50.5-0.60.5-0.5-0.00.40.4
Bone: minimum diameter0.61.22.2-1.0-1.0-1.0-0.71.5-1.40.9-1.3-1.30.8
Time in familiar zone, hab. session 10.10.10.6-0.10.40.20.20.3-0.3-0.80.10.40.4
Time in novel zone, hab. session 10.20.20.7-0.2-0.6-0.4-0.4-0.10.10.9-0.3-0.60.1
Total zone transitions, hab. session 10.10.10.30.2-0.00.1-0.0-0.60.50.30.20.1-0.3
Total locomotion distance, hab. session 10.10.10.30.3-0.00.10.1-0.50.50.20.2-0.0-0.3
Locomotion velocity, hab. session 10.10.10.20.1-0.2-0.0-0.0-0.50.50.4-0.1-0.2-0.0
Time in familiar zone, hab. session 20.30.30.80.40.90.70.8-0.30.3-0.80.40.50.2
Time in novel zone, hab. session 20.20.20.80.30.10.1-0.1-0.30.2-0.40.60.6-0.9
Total zone transitions, hab. session 20.20.30.5-0.5-0.7-0.6-0.60.3-0.30.6-0.7-0.50.3
Total locomotion distance, hab. session 20.00.00.00.1-0.1-0.0-0.1-0.10.1-0.0-0.1-0.1-0.2
Locomotion velocity, hab. session 20.00.00.10.1-0.2-0.00.0-0.20.30.2-0.3-0.3-0.0
Novel to familiar place preference ratio1.62.13.61.61.41.31.1-1.41.4-1.31.41.5-1.9
Novelty place preference1.52.03.01.51.31.31.1-1.51.5-1.21.41.4-1.7
Time in novel zone, NPP test1.21.52.51.31.11.11.0-1.21.2-1.11.21.3-1.6
Total zone transitions, NPP test0.10.10.40.0-0.1-0.2-0.30.0-0.1-0.30.10.4-0.7
Total locomotion distance, NPP test0.00.00.20.1-0.0-0.0-0.10.1-0.1-0.2-0.20.1-0.4
Locomotion velocity, NPP test0.20.30.80.70.50.50.4-0.50.5-0.50.30.6-0.9
Intraocular pressure0.60.91.6-1.0-1.1-1.1-1.20.8-0.81.2-0.7-0.60.6
Delta distance traveled before/after self-admin0.00.00.20.10.10.20.3-0.30.30.1-0.1-0.20.4
Delta ambulatory time before/after self-admin0.40.61.40.80.81.01.0-1.11.2-0.40.50.2-0.1
Parametrial fat weight3.37.99.9-2.7-3.0-2.8-2.42.9-2.83.0-3.0-3.12.1
Pavlov. Cond. lever latency0.30.31.00.90.50.60.7-0.30.4-0.30.30.0-1.0
Pavlov. Cond. magazine entry latency0.50.62.2-1.2-0.6-0.8-1.10.2-0.40.3-0.30.11.5
Pavlov. Cond. change in total contacts2.62.94.4-2.1-1.8-1.9-2.01.4-1.51.5-1.4-1.11.9
Pavlov. Cond. index score1.31.73.8-1.8-1.2-1.4-1.60.8-0.91.0-1.0-0.51.9
Pavlov. Cond. latency score0.91.22.4-1.5-1.0-1.2-1.50.8-1.00.7-0.7-0.31.5
Pavlov. Cond. lever contacts0.50.72.4-1.2-0.7-0.8-1.00.2-0.30.6-0.5-0.11.5
Pavlov. Cond. magazine entry number1.41.85.11.91.31.41.6-0.60.8-1.10.90.6-2.3
Pavlov. Cond. intertrial magazine entries0.60.71.41.00.60.80.9-1.01.0-0.21.20.2-0.9
Pavlov. Cond. lever-magazine prob. diff.1.92.35.2-2.1-1.5-1.6-1.81.0-1.11.3-1.3-0.72.3
Pavlov. Cond. response bias1.51.85.6-1.8-1.3-1.3-1.60.5-0.61.3-0.9-0.62.4
Pavlov. Cond. lever latency0.10.20.5-0.4-0.3-0.3-0.7-0.40.20.50.20.60.2
Pavlov. Cond. magazine entry latency0.10.20.7-0.6-0.3-0.3-0.30.4-0.40.3-0.4-0.40.8
Pavlov. Cond. change in total contacts0.10.20.50.50.20.30.50.3-0.2-0.40.2-0.3-0.7
Pavlov. Cond. index score0.10.20.7-0.3-0.3-0.20.00.6-0.50.3-0.5-0.80.5
Pavlov. Cond. latency score0.10.20.6-0.3-0.3-0.20.00.6-0.50.3-0.4-0.80.4
Pavlov. Cond. lever contacts0.10.20.60.40.30.40.70.3-0.2-0.4-0.1-0.6-0.2
Pavlov. Cond. magazine entry number0.10.20.50.30.30.30.2-0.70.6-0.20.40.5-0.3
Pavlov. Cond. intertrial magazine entries0.20.50.70.70.70.60.5-0.80.8-0.60.80.8-0.6
Pavlov. Cond. lever-magazine prob. diff.0.20.30.9-0.4-0.4-0.4-0.10.7-0.60.5-0.6-0.90.6
Pavlov. Cond. response bias0.10.10.50.10.00.10.40.5-0.4-0.2-0.3-0.70.1
Time in closed arm before self-admin0.10.10.5-0.10.10.20.1-0.60.50.00.10.10.7
Time in closed arm after self-admin0.20.20.4-0.10.50.30.2-0.40.3-0.70.30.60.5
Time in open arm before self-admin0.40.51.0-0.7-0.7-0.7-0.61.0-1.00.7-0.6-0.70.4
Time in open arm after self-admin0.80.92.1-0.5-0.9-0.7-0.40.9-0.81.3-1.1-1.50.5
Bone: periosteal estimation1.33.25.9-1.7-1.8-1.8-1.52.4-2.31.4-1.7-1.80.8
Bone: periosteal perimeter1.02.04.8-1.0-1.3-1.1-0.61.8-1.61.3-1.5-2.20.7
Bone: post-yield work1.93.26.7-2.1-1.6-2.1-2.12.5-2.60.9-1.3-0.60.8
Progressive ratio test 1 active lever presses0.20.41.2-0.6-0.8-0.9-1.10.5-0.50.50.2-0.0-0.2
Progressive ratio test 1 breakpoint0.20.41.2-0.6-0.8-0.9-1.10.5-0.50.40.20.0-0.2
Progressive ratio test 1 inactive lever presses0.30.81.70.70.90.80.6-0.90.8-0.91.31.2-0.9
Progressive ratio test 2 active lever presses0.20.20.50.30.00.1-0.2-0.70.6-0.10.70.6-0.5
Progressive ratio test 2 breakpoint0.10.20.40.2-0.00.0-0.2-0.60.6-0.00.60.5-0.3
Progressive ratio test 2 inactive lever presses0.10.31.3-0.10.1-0.2-0.5-0.20.0-0.50.61.1-0.5
Incentive Sensitization - Responses0.10.30.70.30.40.40.2-0.80.8-0.40.40.8-0.0
Incentive Sensitization - Breakpoint0.10.20.70.20.30.30.1-0.80.7-0.30.30.70.1
Sum of active levers in priming session hrs 5-60.70.71.0-0.8-0.7-0.7-0.60.8-0.80.8-1.0-0.80.9
Progressive ratio0.20.51.30.50.60.40.3-0.00.0-0.91.01.0-1.1
Food seeking constrained by brief footshock0.20.30.70.30.70.60.5-0.60.5-0.60.30.80.0
Seeking ratio, punishment vs. effort0.10.20.9-0.00.10.20.3-0.60.60.3-0.5-0.30.9
Retroperitoneal fat weight1.04.36.4-2.2-2.4-2.3-2.21.7-1.82.5-1.9-2.01.5
Reaction time number correct0.41.52.31.41.41.31.5-0.50.6-1.41.30.7-1.5
Reaction time mean minus median1.27.610.6-3.2-2.8-2.9-3.12.0-2.22.8-3.1-1.83.3
Reaction time mean minus median AUC1.17.210.2-3.2-2.8-2.9-3.22.0-2.22.7-2.8-1.62.9
Reaction time num false alarms1.83.16.62.11.81.71.8-0.80.9-2.11.81.3-2.6
Reaction time num false alarms AUC1.22.65.42.01.61.61.8-0.70.9-1.91.61.0-2.3
Reaction time trials correct on left0.41.52.31.41.41.31.5-0.50.6-1.41.30.7-1.5
Reaction time trials on left0.41.42.31.41.31.21.4-0.40.5-1.41.30.7-1.5
Reaction time mean0.92.13.0-1.7-1.3-1.6-1.71.5-1.61.3-1.5-0.61.4
Reaction time mean AUC0.61.42.2-1.5-1.0-1.3-1.41.2-1.31.0-1.3-0.31.3
Median of all reaction times0.30.51.0-0.9-0.5-0.8-0.90.9-1.00.5-0.60.00.6
Reaction time omissions1.01.62.8-1.4-1.2-1.4-1.41.6-1.70.8-1.0-0.70.7
Reaction time false alarm rate0.50.71.71.10.80.81.0-0.50.6-1.00.80.4-1.3
Reaction time premature initiation rate0.30.41.30.40.50.50.3-1.11.0-0.20.60.80.2
Reaction time premature initiations0.30.81.20.80.90.90.8-1.11.1-0.71.00.9-0.4
Std. dev. reaction times1.65.37.3-2.7-2.3-2.5-2.62.1-2.22.2-2.4-1.42.3
Reaction time trials completed0.41.42.31.41.31.21.4-0.40.5-1.41.30.7-1.5
Reaction time trials AUC0.31.12.01.21.11.11.3-0.20.4-1.21.10.5-1.4
Run reversals in cocaine runway, females4.24.86.8-2.2-2.2-2.0-1.71.8-1.72.3-2.4-2.52.6
Run reversals in cocaine runway, males1.01.12.1-1.3-1.0-1.3-1.51.2-1.30.5-0.7-0.00.8
Latency to leave start box in cocaine runway0.20.31.5-0.7-0.3-0.3-0.30.3-0.30.3-0.5-0.41.2
Latency to leave start box in cocaine runway, F0.10.10.3-0.5-0.1-0.3-0.40.3-0.3-0.0-0.10.10.6
Latency to leave start box in cocaine runway, M0.20.20.9-0.4-0.3-0.2-0.10.3-0.30.4-0.6-0.60.9
Std. dev. time between licks in bursts0.20.40.70.70.60.70.6-0.80.8-0.60.60.5-0.6
Total sessions with >9 infusions0.30.31.10.70.50.50.5-0.30.3-0.51.00.5-0.7
Short access day 1 total inactive lever presses0.61.32.21.21.21.41.5-1.41.5-0.71.00.3-0.4
Short access day 10 total inactive lever presses0.00.00.10.00.20.10.10.2-0.2-0.2-0.00.1-0.3
Short access day 1 total infusions0.10.10.5-0.2-0.4-0.3-0.20.1-0.10.7-0.0-0.60.3
Short access day 10 total infusions0.20.31.20.10.2-0.0-0.3-0.10.0-0.71.11.0-0.4
Short access total infusions0.10.21.10.10.1-0.0-0.3-0.20.1-0.31.00.7-0.5
Short access day 1 locomotion0.10.20.70.5-0.10.30.5-0.50.60.50.2-0.8-0.3
Short access day 10 total locomotion0.10.30.9-0.3-0.6-0.6-0.50.9-0.90.2-0.2-0.4-0.1
Short access total locomotion0.10.20.7-0.1-0.5-0.3-0.20.3-0.20.60.0-0.80.2
One hour access (0.3 mA shock)0.30.31.5-0.20.40.1-0.3-0.70.5-0.60.51.20.5
Compulsive drug intake0.20.20.70.10.60.50.3-0.50.4-0.60.50.8-0.0
One hour access (shock baseline)0.41.03.00.60.90.60.2-1.00.9-1.21.31.7-0.6
Social response proportion0.00.10.1-0.1-0.1-0.2-0.20.3-0.40.0-0.40.1-0.3
Social responses0.60.81.2-0.8-0.8-0.8-0.61.0-1.00.8-1.1-0.90.8
Social time0.40.61.6-0.00.3-0.2-0.40.8-0.8-0.90.81.3-1.2
Soleus weight0.20.61.7-0.4-0.8-0.4-0.3-0.40.41.3-0.4-1.21.1
Bone: stiffness2.13.98.0-1.9-1.9-2.2-2.02.8-2.81.4-1.6-1.40.4
Tibialis anterior weight6.121.127.6-4.9-5.3-5.0-4.93.8-3.95.1-4.4-4.34.1
Time to tail flick, vehicle, before self-admin0.60.82.1-0.6-0.7-1.0-1.01.4-1.4-0.1-0.5-0.0-0.9
Time to tail flick, vehicle, after self-admin2.04.08.52.21.81.71.4-1.61.6-2.31.82.3-2.9
Time to tail flick, test, before self-admin0.20.20.9-0.4-0.4-0.2-0.3-0.40.30.7-0.3-0.30.9
Time to tail flick, test, after self-admin1.51.62.61.11.11.10.8-1.21.2-1.41.61.5-1.3
Delta time to tail flick, vehicle, before/after SA6.16.57.72.82.62.62.4-2.72.7-2.42.52.4-2.4
Delta time to tail flick, test, before/after SA0.50.61.40.80.70.60.5-0.70.6-0.90.80.8-1.2
Tibia length0.10.31.0-0.3-0.6-0.6-0.51.0-0.90.1-0.2-0.5-0.4
Ambulatory time before self-admin2.26.67.5-2.6-2.7-2.7-2.42.7-2.72.5-2.7-2.62.1
Ambulatory time after self-admin2.43.95.0-2.0-2.0-1.9-1.71.8-1.72.0-2.2-2.22.2
Bone: tissue strength0.20.20.4-0.10.0-0.2-0.20.6-0.6-0.5-0.10.4-0.6
Total heroin consumption0.60.71.1-0.9-0.8-0.9-0.90.9-0.90.6-1.1-0.60.7
Bone: trabecular number1.12.13.71.41.41.31.0-1.51.4-1.61.31.9-1.5
Bone: trabecular spacing0.10.20.4-0.2-0.4-0.4-0.30.6-0.50.40.1-0.5-0.3
Bone: trabecular thickness0.60.81.10.61.11.00.9-1.01.0-0.90.70.90.2
Bone: trabecular tissue density1.93.36.1-1.6-1.6-1.7-1.22.5-2.31.5-2.0-2.11.3
Water consumed over 24 hours0.20.50.9-0.7-0.6-0.7-0.71.0-1.0-0.0-0.8-0.30.3
Number of responses in last shaping day0.10.10.20.3-0.10.20.2-0.40.40.4-0.3-0.40.0