Hub : Genes

Armc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Armc1 0.31 0.15 1.1e-03 0.09 0.08 0.04 0.09 4.7e-03 5.9e-03 4.3e-02 4.0e-03
2 NAcc gene expression Armc1 0.14 0.09 6.2e-08 0.05 0.04 0.04 0.04 3.3e-06 5.1e-06 3.7e-05 2.4e-05
3 Brain mRNA stability Armc1 0.05 0.03 2.3e-04 0.01 0.02 0.01 0.02 1.3e-02 5.4e-03 1.7e-02 9.1e-03
4 PL gene expression Armc1 0.04 0.02 3.5e-05 0.03 0.03 0.02 0.02 3.9e-04 5.9e-04 4.3e-03 2.1e-03
5 Brain gene expression Armc1 0.04 0.02 4.9e-04 0.03 0.03 0.03 0.03 8.3e-04 3.8e-04 6.2e-04 6.3e-04
6 LHb alternative TSS NM_001106425.2 0.25 0.13 4.5e-03 -0.01 0.03 -0.01 0.01 7.1e-01 8.6e-02 8.8e-01 2.3e-01
7 IL gene expression Armc1 0.13 0.09 6.5e-03 0.01 0.03 -0 0.03 1.4e-01 6.5e-02 4.0e-01 7.8e-02
8 LHb alternative TSS XM_039101979.1 0.28 0.13 2.3e-03 -0.01 0.03 -0.01 0.01 6.2e-01 5.8e-02 7.5e-01 1.6e-01
9 pVTA gene expression Armc1 0.16 0.1 4.0e-04 0.03 0.04 0.04 0.04 1.7e-02 7.9e-03 5.8e-03 8.7e-03
10 Liver gene expression Armc1 0.04 0.03 9.1e-03 0.01 0.01 0 0.01 3.2e-02 4.0e-02 1.7e-01 4.9e-02
11 BLA gene expression Armc1 0.12 0.07 8.2e-05 0.02 0.02 0.03 0.02 3.8e-02 2.5e-02 1.1e-02 4.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.72.94.61.4-1.7-2.1-2.01.8-2.01.91.9-1.6-0.6-1.0
Area under the delay curve0.10.10.5-0.70.1-0.0-0.4-0.4-0.2-0.20.2-0.50.5-0.1
BMI with tail1.34.27.2-2.52.52.31.7-1.82.7-1.6-2.62.20.50.4
BMI without tail2.04.110.0-3.22.61.71.9-1.91.9-1.4-1.82.31.81.0
Body weight1.66.610.5-2.73.23.12.4-2.82.9-2.7-2.82.41.01.2
Weight adjusted by age0.60.61.8-0.30.51.00.7-1.00.5-1.1-0.50.60.31.3
Bone surface0.20.40.90.4-0.5-0.7-0.90.7-0.50.70.5-0.5-0.3-0.9
Bone volume0.20.40.80.5-0.6-0.8-0.90.7-0.70.70.6-0.5-0.2-0.6
Breakpoint value in progressive ratio session0.20.21.1-0.40.3-0.20.50.1-0.00.30.01.00.50.8
Number of licking bursts1.41.62.6-0.91.51.61.5-1.51.3-1.6-1.21.40.70.1
Context. condit. distance diff. score0.30.41.10.10.90.80.9-0.90.3-1.1-0.2-0.3-0.20.1
Locomotion velocity, session 10.20.20.6-0.80.60.20.3-0.6-0.0-0.40.1-0.00.70.1
Locomotion distance, session 10.20.20.7-0.3-0.1-0.1-0.40.50.50.6-0.50.1-0.7-0.8
Locomotion velocity, session 21.01.24.4-2.11.30.80.8-1.20.7-0.9-0.60.71.30.2
Locomotion distance, session 20.30.41.1-0.2-0.3-0.1-0.80.50.60.5-0.6-0.1-1.1-0.9
Locomotion velocity, session 30.80.91.8-1.31.31.10.9-1.20.9-1.1-0.90.60.60.1
Locomotion distance, session 30.50.61.1-1.11.00.70.7-1.10.3-0.9-0.20.00.80.6
Stereotopy head waving bouts, day 30.10.10.40.6-0.6-0.1-0.20.3-0.20.10.2-0.4-0.4-0.2
Stereotopy head waving duration, day 30.30.40.90.8-0.9-0.5-0.40.9-0.10.8-0.00.1-0.7-0.4
Locomotion velocity, session 71.81.94.02.0-1.6-1.0-1.81.5-0.61.20.5-1.3-1.9-0.8
Locomotion distance, session 71.62.15.02.2-1.8-1.3-1.51.6-1.21.31.1-1.1-1.4-0.4
Stereotopy head waving bouts, day 70.30.30.7-0.70.60.60.6-0.80.3-0.8-0.30.10.40.2
Stereotopy head waving duration, day 70.30.40.8-0.90.70.50.7-0.80.2-0.7-0.20.40.80.3
Locomotion velocity, session 80.60.81.7-1.31.20.90.8-1.10.8-0.9-0.80.30.40.6
Locomotion distance, session 80.91.32.2-1.21.51.51.1-1.31.3-1.3-1.30.70.1-0.0
Degree of sensitization distance3.33.36.12.4-2.4-1.9-1.92.5-1.22.21.1-0.6-1.6-0.8
Degree of sensitization stereotypy1.71.83.6-1.71.81.51.5-1.90.9-1.8-0.80.61.10.4
Conditioned locomotion1.61.93.11.3-1.5-1.4-1.81.5-1.01.41.0-1.7-1.3-1.0
Cocaine response after cond. corrected0.20.21.20.5-0.4-0.20.30.1-0.40.00.40.20.41.1
Cocaine response after cond. not corrected0.20.21.10.5-0.4-0.10.40.1-0.4-0.00.30.40.31.0
Cocaine response before conditioning0.20.20.40.4-0.3-0.3-0.50.60.10.6-0.1-0.0-0.6-0.6
Saline control response0.71.01.8-0.81.11.21.0-0.81.3-0.8-1.31.30.00.0
Bone: connectivity density2.64.18.01.0-2.0-2.8-2.32.3-2.52.52.5-1.7-0.1-1.0
Bone: cortical apparent density1.01.32.5-1.51.50.91.4-1.60.2-1.4-0.10.31.50.1
Bone: cortical area0.81.32.80.70.91.70.2-0.91.5-1.4-1.5-0.2-1.5-0.5
Bone: cortical porosity0.70.72.90.9-0.9-0.1-0.90.90.50.7-0.6-0.3-1.7-1.0
Bone: cortical porosity0.50.52.30.7-0.60.1-0.80.50.50.3-0.6-0.5-1.5-0.6
Bone: cortical thickness1.01.66.31.7-0.20.8-0.90.00.7-0.6-0.7-1.6-2.5-1.6
Bone: cortical thickness0.50.51.1-0.40.71.0-0.1-0.51.0-0.7-1.00.1-0.7-0.9
Bone: cortical tissue density1.11.53.2-1.71.60.81.5-1.70.1-1.40.00.41.80.2
Condit. Reinf. active minus inactive responses0.40.42.1-0.3-0.10.2-0.40.40.80.4-0.80.3-0.6-1.4
Condit. Reinf. active-inactive response ratio0.20.21.0-0.0-0.2-0.3-0.40.50.20.6-0.20.0-0.2-1.0
Condit. Reinf. active responses0.30.32.1-0.80.10.1-0.50.00.60.2-0.5-0.0-0.2-1.4
Condit. Reinf. inactive responses0.30.31.2-1.10.50.50.0-0.60.6-0.4-0.60.40.4-0.5
Incentive salience index mean0.20.31.0-0.70.30.40.2-0.10.8-0.1-0.80.60.0-1.0
Condit. Reinf. lever presses0.30.41.6-1.10.50.10.6-0.5-0.0-0.20.10.71.3-0.1
Condit. Reinf. active minus inactive responses0.20.20.60.10.40.60.2-0.30.5-0.5-0.5-0.3-0.8-0.6
Condit. Reinf. active-inactive response ratio0.10.10.6-0.10.20.0-0.1-0.2-0.1-0.20.2-0.8-0.3-0.4
Condit. Reinf. active responses0.30.41.80.50.20.70.00.00.9-0.2-1.00.2-1.3-0.4
Condit. Reinf. inactive responses0.50.61.60.60.20.90.3-0.11.2-0.4-1.30.9-1.10.3
Condit. Reinf. lever presses0.10.20.70.8-0.30.0-0.00.50.30.3-0.30.5-0.80.3
Condit. Reinf. lever reinforcers received0.30.41.60.40.10.60.00.00.9-0.2-0.90.2-1.3-0.6
Conditioned reinforcement - actives0.50.51.10.2-0.8-1.0-0.60.8-0.90.90.9-0.40.00.4
Conditioned reinforcement - inactives0.80.92.6-0.5-0.2-1.00.10.1-1.30.51.40.21.61.5
Conditioned locomotion0.60.72.0-1.00.70.40.6-1.1-0.2-0.90.30.21.41.2
Patch foraging indifference point 0 sec0.40.61.2-0.50.80.51.0-1.1-0.4-1.10.40.21.10.9
Patch foraging indifference point AUC0.10.10.7-0.60.30.0-0.1-0.00.30.1-0.2-0.3-0.3-0.8
Delay disc. indifference point, 0s delay0.20.31.20.20.10.60.3-0.30.7-0.5-0.7-0.1-1.1-0.1
Delay disc. indifference point, 16s delay0.50.51.40.0-0.7-0.7-1.20.5-0.60.60.7-1.10.0-0.8
Delay disc. indifference point, 2s delay0.10.10.4-0.20.30.2-0.1-0.5-0.3-0.50.3-0.60.40.3
Delay disc. indifference point, 24s delay1.91.83.21.1-1.5-1.4-1.81.1-1.51.11.5-1.7-0.4-1.2
Delay disc. indifference point, 4s delay1.01.14.4-2.11.30.60.6-1.10.6-0.7-0.50.81.30.5
Delay disc. indifference point, 8s delay0.20.21.1-0.90.3-0.1-0.1-0.4-0.3-0.20.3-0.21.10.1
Indifference point function ln k1.11.65.9-1.41.20.41.4-1.1-0.2-0.80.31.32.41.5
Indifference point function log k1.11.65.9-1.41.20.41.4-1.1-0.2-0.80.31.32.41.5
Patch foraging total patch changes 0 sec0.81.32.6-0.91.20.81.5-1.5-0.2-1.40.30.61.61.3
Patch foraging total patch changes 12 sec0.10.10.20.00.20.30.2-0.40.0-0.4-0.0-0.4-0.40.3
Patch foraging total patch changes 18 sec0.10.20.4-0.60.50.50.4-0.50.5-0.5-0.40.1-0.20.0
Patch foraging total patch changes 24 sec0.10.20.3-0.2-0.5-0.5-0.30.2-0.60.40.6-0.40.20.3
Patch foraging total patch changes 6 sec0.50.81.8-1.31.10.60.9-1.10.2-0.8-0.20.41.21.0
Patch foraging time to switch 0 sec0.10.10.30.1-0.20.30.10.10.5-0.0-0.50.5-0.40.5
Patch foraging water rate 0 sec0.30.41.6-0.70.4-0.40.1-0.4-0.9-0.20.9-0.51.30.3
Patch foraging water rate 12 sec0.20.41.10.5-0.6-0.5-1.10.8-0.20.70.1-0.4-0.6-0.5
Patch foraging water rate 18 sec0.10.20.30.3-0.6-0.6-0.60.5-0.40.60.4-0.4-0.10.3
Patch foraging water rate 24 sec0.30.50.90.0-0.6-0.9-0.80.5-0.90.60.9-0.90.2-0.4
Patch foraging water rate 6 sec0.60.92.8-0.90.90.51.1-1.1-0.0-0.90.10.71.71.0
Seeking ratio, delayed vs. immediate footshock3.13.55.72.4-2.2-2.0-1.81.6-2.41.42.3-2.3-0.50.2
Distance traveled before self-admin2.72.94.5-1.82.12.01.7-1.91.8-1.9-1.71.40.81.3
Distance traveled after self-admin4.44.97.1-1.72.72.62.5-2.52.0-2.5-2.02.51.51.4
Extensor digitorum longus weight4.317.029.0-5.45.34.34.5-4.63.7-4.1-3.53.83.21.4
Bone: elastic displacement2.32.65.01.7-1.6-1.7-1.71.4-1.81.31.8-2.2-1.0-0.8
Bone: elastic work0.81.02.11.0-0.8-1.1-1.10.7-1.30.71.3-1.4-0.3-0.3
Bone: endosteal estimation1.53.27.4-1.61.81.92.0-1.22.4-1.2-2.42.70.40.6
Bone: endosteal perimeter1.83.86.2-0.92.12.52.4-2.02.1-2.3-2.12.20.61.4
Epididymis fat weight2.14.98.7-1.82.82.72.4-2.91.9-2.9-1.81.71.40.8
Delta time in closed arm before/after self-admin0.50.52.1-0.1-0.2-0.5-1.00.80.20.9-0.2-0.0-0.5-1.5
Delta time in open arm before/after self-admin0.20.20.90.30.10.30.5-0.4-0.1-0.60.1-0.4-0.01.0
Diff in mean of infusions in LGA sessions0.30.30.60.4-0.7-0.8-0.20.7-0.70.80.60.20.1-0.1
Delay discount exponential model param0.10.10.40.6-0.2-0.00.40.40.20.3-0.20.5-0.60.0
Extinction: sum of active levers before priming0.10.10.50.7-0.2-0.1-0.40.3-0.10.10.1-0.4-0.6-0.3
Active lever presses in extinction session 61.51.54.7-0.20.21.00.30.42.10.2-2.21.7-1.7-0.4
Bone: final force1.32.15.9-0.61.21.90.7-0.92.4-1.1-2.41.1-1.2-0.9
Bone: final moment1.32.15.9-0.41.11.90.6-0.82.4-1.1-2.41.1-1.3-0.9
Food consumed during 24 hour testing period3.64.36.5-2.42.62.22.2-2.02.2-1.8-2.22.51.30.6
Glucose0.91.43.8-0.91.11.40.7-0.71.9-0.8-1.91.2-0.7-0.3
Heart weight0.91.23.60.3-0.7-1.2-1.00.3-1.90.41.9-1.41.00.4
Delay discount hyperbolic model param0.10.10.50.7-0.3-0.20.20.50.00.3-0.10.3-0.6-0.1
Intermittent access intake day 1-15 change0.80.81.7-1.31.11.00.6-1.10.9-0.9-0.80.40.60.4
Intermittent access intake escalation0.70.62.0-1.41.00.70.3-0.61.1-0.4-1.00.70.30.3
Intermittent access intake escalation 21.21.22.4-1.61.31.30.7-1.11.4-1.0-1.30.80.50.1
Intermitt. access day 1 inactive lever presses0.60.62.5-0.4-0.6-0.9-0.71.20.11.6-0.10.9-0.10.6
Intermitt. access day 15 inactive lever presses0.80.93.60.1-0.9-1.3-0.81.6-0.31.90.20.0-0.90.0
Intermitt. access escalation Index0.20.10.20.3-0.4-0.5-0.30.4-0.40.50.40.10.30.2
Intermittent access day 1 total infusions0.70.82.0-0.2-0.7-1.4-0.70.8-1.21.21.3-0.80.20.4
Intermittent access day 15 total infusions0.40.41.4-0.8-0.3-1.0-0.70.7-0.41.20.4-0.5-0.10.5
Intermittent access terminal intake (last 3 days)0.40.53.4-1.80.7-0.3-0.10.10.40.7-0.30.20.20.5
Intermittent access total infusions1.01.12.8-0.7-0.6-1.7-0.91.1-1.11.71.1-0.70.10.7
Intermittent access day 1 locomotion0.20.20.6-0.80.40.00.3-0.6-0.3-0.40.4-0.50.60.8
Intermittent access day 15 total locomotion1.01.02.6-1.61.20.71.2-1.20.4-0.9-0.30.51.21.1
Intermittent access total locomotion0.20.31.3-1.20.60.10.3-0.50.1-0.2-0.0-0.20.50.8
Intermittent access standard deviation0.80.93.6-1.91.20.60.6-0.90.7-0.5-0.60.60.91.0
Left kidney weight0.20.72.1-0.2-0.1-0.7-0.0-0.3-1.4-0.11.5-0.61.21.1
Right kidney weight0.20.61.6-0.81.10.70.7-1.30.0-1.20.0-0.10.80.7
Cocaine induced anxiety0.50.62.60.6-0.20.4-0.20.40.90.1-1.0-0.2-1.6-1.3
Post-drug Anxiety0.40.41.80.6-0.6-0.3-0.60.70.00.6-0.1-0.3-0.9-1.3
Baseline Anxiety0.70.83.2-0.4-0.0-0.70.0-0.2-1.30.11.4-0.11.81.1
Tail length0.82.43.7-1.71.91.51.7-1.90.8-1.8-0.81.31.81.2
Length with tail0.72.55.9-0.91.92.11.8-2.21.1-2.4-1.10.80.90.9
Length without tail0.40.92.50.80.71.40.4-1.00.8-1.6-0.8-0.6-1.0-0.3
Times rat made contact with spout4.24.97.7-1.22.52.82.6-2.42.3-2.6-2.32.40.81.3
Lifetime Intake1.01.12.9-0.5-0.7-1.6-1.11.2-1.01.71.1-0.8-0.10.6
Liver weight, left2.23.55.3-2.12.12.12.0-1.82.3-1.7-2.32.20.70.3
Liver weight, right1.62.75.2-2.01.71.61.5-1.12.3-0.9-2.22.30.20.4
Locomotor activity0.61.01.6-0.81.01.20.9-0.91.3-0.9-1.31.2-0.00.4
Locomotor testing distance1.01.73.3-0.81.31.71.3-1.21.8-1.3-1.81.4-0.5-0.1
Locomotor testing rearing0.50.72.40.6-0.10.90.40.11.3-0.3-1.40.9-1.6-0.1
Locomotion in novel chamber0.40.51.0-0.10.81.00.8-0.80.8-1.0-0.80.0-0.40.2
Locomotion in novel chamber post-restriction0.91.02.20.5-1.0-1.2-1.21.4-0.61.50.6-0.7-0.6-1.4
Fecal boli incidents, locomotor time 11.21.32.80.1-0.7-0.3-0.91.41.21.4-1.20.8-1.7-1.7
Change in fecal boli incidents, locomotor task1.71.65.62.4-1.0-0.4-1.20.3-1.2-0.21.1-2.1-1.3-0.1
Time >=10cm from walls, locomotor time 10.30.31.01.0-0.8-0.2-0.50.6-0.00.4-0.0-0.5-0.70.2
Bouts of movement, locomotor time 10.60.71.6-0.4-0.5-1.2-0.30.6-1.20.91.3-0.70.60.5
Total resting periods, locomotor time 10.80.92.3-0.4-0.5-1.4-0.30.6-1.50.91.5-0.80.80.6
Rest time, locomotor task time 10.50.51.9-1.40.40.00.40.20.90.6-0.91.2-0.0-0.5
Distance moved, locomotor task time 10.50.61.60.90.40.80.8-0.80.1-1.1-0.10.50.41.3
Vertical activity count, locomotor time 11.11.13.30.20.70.91.1-1.20.0-1.4-0.10.91.41.8
Time >=10cm from walls, locomotor time 20.70.83.21.5-0.90.0-0.70.60.30.2-0.3-0.9-1.8-0.3
Bouts of movement, locomotor time 20.91.02.5-0.4-0.6-1.4-0.60.6-1.50.91.6-1.20.5-0.5
Total resting periods, locomotor time 20.90.92.3-0.6-0.6-1.4-0.50.6-1.40.91.5-1.00.6-0.3
Rest time, locomotor task time 20.50.62.3-1.0-0.3-1.0-0.31.1-0.11.50.10.60.0-0.4
Distance moved, locomotor task time 20.20.21.51.2-0.40.30.10.0-0.0-0.4-0.00.1-0.20.2
Vertical activity count, locomotor time 20.91.03.2-0.70.70.81.0-0.70.7-0.6-0.81.81.31.2
Light reinforcement 10.61.12.0-0.91.21.21.3-1.40.7-1.4-0.70.70.60.8
Light reinforcement 23.85.010.5-1.42.32.42.8-3.10.8-3.2-0.71.42.42.3
Bone: marrow area1.43.17.6-1.61.71.82.0-1.22.3-1.1-2.32.80.40.6
Bone: maximum diameter0.91.63.70.11.31.90.9-1.21.7-1.6-1.80.8-0.70.4
Bone: maximum force1.52.57.0-0.81.42.00.9-0.92.6-1.1-2.61.7-1.0-0.7
Bone: maximum moment1.42.47.0-0.61.32.00.9-0.82.6-1.0-2.61.6-1.2-0.7
Mean time between licks in bursts0.60.82.5-1.60.60.20.8-0.40.50.0-0.41.41.40.8
Mean num. licks in bursts0.10.10.30.30.10.20.10.20.40.1-0.40.2-0.50.5
Cd content in liver0.30.30.9-1.00.60.60.2-0.60.7-0.5-0.70.2-0.1-0.7
Co content in liver2.42.86.3-0.71.32.01.9-1.12.2-1.3-2.32.50.11.2
Cu content in liver0.00.10.20.3-0.20.10.20.10.1-0.1-0.1-0.1-0.3-0.4
Fe content in liver0.40.41.80.6-0.5-0.0-0.50.60.40.4-0.4-0.1-1.1-1.4
K content in liver0.30.30.70.7-0.5-0.8-0.20.6-0.80.60.8-0.20.20.1
Mg content in liver0.70.71.80.7-0.7-1.1-0.30.7-1.30.71.3-0.70.20.2
Mn content in liver0.10.20.40.3-0.3-0.4-0.50.5-0.20.50.2-0.2-0.3-0.6
Na content in liver0.70.82.3-0.10.91.01.0-1.40.2-1.5-0.20.00.80.7
Rb content in liver1.01.24.31.1-1.2-0.5-1.01.40.31.2-0.4-0.3-2.1-1.0
Se content in liver0.40.52.30.9-0.5-0.1-0.70.50.00.3-0.1-0.7-1.0-1.5
Sr content in liver1.81.63.90.4-1.1-2.0-0.81.4-1.71.81.7-0.70.30.5
Zn content in liver0.40.41.1-0.1-0.4-0.9-0.00.4-1.00.61.0-0.00.90.5
Bone: minimum diameter0.71.32.5-0.11.01.51.3-0.91.5-1.2-1.61.4-0.20.6
Time in familiar zone, hab. session 10.30.31.30.3-0.4-0.10.20.50.30.5-0.41.10.10.8
Time in novel zone, hab. session 10.20.20.5-0.50.50.20.1-0.7-0.2-0.60.3-0.60.3-0.2
Total zone transitions, hab. session 10.10.20.9-0.2-0.0-0.4-0.5-0.0-0.60.10.6-0.90.2-0.2
Total locomotion distance, hab. session 10.10.10.8-0.1-0.1-0.2-0.3-0.2-0.4-0.10.5-0.9-0.0-0.4
Locomotion velocity, hab. session 10.10.10.6-0.30.2-0.1-0.0-0.4-0.5-0.30.5-0.80.4-0.0
Time in familiar zone, hab. session 20.30.30.60.8-0.8-0.5-0.20.7-0.40.60.30.50.1-0.3
Time in novel zone, hab. session 20.20.20.50.0-0.3-0.4-0.70.5-0.20.60.2-0.7-0.70.3
Total zone transitions, hab. session 20.20.20.6-0.80.60.50.3-0.60.3-0.6-0.20.20.3-0.3
Total locomotion distance, hab. session 20.00.10.3-0.20.00.0-0.2-0.1-0.1-0.10.1-0.4-0.1-0.5
Locomotion velocity, hab. session 20.10.10.3-0.20.20.1-0.0-0.4-0.2-0.40.3-0.50.1-0.3
Novel to familiar place preference ratio1.92.02.61.4-1.5-1.5-1.61.5-1.21.41.2-1.6-1.4-1.1
Novelty place preference1.81.82.61.3-1.5-1.5-1.61.4-1.31.31.3-1.6-1.2-1.0
Time in novel zone, NPP test1.41.41.91.1-1.3-1.3-1.41.3-1.11.21.0-1.3-1.1-0.9
Total zone transitions, NPP test0.10.10.4-0.3-0.2-0.2-0.40.30.20.4-0.1-0.2-0.6-0.6
Total locomotion distance, NPP test0.10.10.4-0.0-0.20.1-0.10.10.30.0-0.3-0.0-0.6-0.4
Locomotion velocity, NPP test0.20.30.80.5-0.7-0.4-0.60.6-0.20.50.2-0.6-0.9-0.7
Intraocular pressure0.40.51.9-1.40.70.70.6-0.80.7-0.6-0.60.60.40.6
Delta distance traveled before/after self-admin0.10.10.30.40.30.40.3-0.30.1-0.5-0.20.30.1-0.3
Delta ambulatory time before/after self-admin0.20.20.70.8-0.2-0.1-0.1-0.0-0.6-0.20.6-0.40.1-0.5
Parametrial fat weight3.16.110.0-2.53.12.92.5-3.22.0-3.1-1.92.02.01.2
Pavlov. Cond. lever latency0.30.31.40.9-0.00.2-0.50.00.1-0.2-0.1-0.9-1.2-0.5
Pavlov. Cond. magazine entry latency0.70.93.6-1.50.2-1.00.20.2-0.70.90.80.71.90.5
Pavlov. Cond. change in total contacts1.61.74.8-2.21.40.81.5-1.20.8-0.8-0.81.51.80.5
Pavlov. Cond. index score1.11.45.1-2.11.00.11.2-0.70.1-0.1-0.01.42.31.0
Pavlov. Cond. latency score0.70.93.0-1.70.80.11.0-0.40.30.0-0.31.31.70.9
Pavlov. Cond. lever contacts0.91.04.9-1.70.6-0.20.9-0.5-0.30.00.41.02.20.8
Pavlov. Cond. magazine entry number1.51.87.52.3-1.3-0.1-1.21.00.10.4-0.2-1.4-2.7-1.0
Pavlov. Cond. intertrial magazine entries0.60.82.70.7-0.9-0.4-1.20.2-0.80.10.8-1.6-0.7-1.1
Pavlov. Cond. lever-magazine prob. diff.1.72.16.8-2.41.30.31.5-1.00.2-0.4-0.21.72.61.3
Pavlov. Cond. response bias1.72.09.3-2.61.2-0.21.2-0.9-0.4-0.20.51.23.01.0
Pavlov. Cond. lever latency0.40.51.0-1.0-0.3-0.9-0.90.5-0.60.90.7-0.70.7-0.5
Pavlov. Cond. magazine entry latency0.20.20.8-0.10.30.20.7-0.30.1-0.2-0.10.90.60.3
Pavlov. Cond. change in total contacts0.30.41.91.1-0.10.50.20.10.6-0.3-0.60.1-1.4-0.4
Pavlov. Cond. index score0.30.30.80.40.40.70.9-0.50.5-0.7-0.60.9-0.20.3
Pavlov. Cond. latency score0.30.40.90.30.50.80.9-0.50.6-0.7-0.70.9-0.20.3
Pavlov. Cond. lever contacts0.40.61.41.20.10.90.7-0.20.7-0.7-0.80.7-1.20.3
Pavlov. Cond. magazine entry number0.20.30.9-0.3-0.3-0.6-0.60.2-0.70.40.7-0.90.3-0.1
Pavlov. Cond. intertrial magazine entries0.40.51.40.3-0.7-0.8-1.20.6-0.70.70.7-1.0-0.3-0.7
Pavlov. Cond. lever-magazine prob. diff.0.40.61.20.10.70.91.1-0.70.7-0.9-0.71.10.00.4
Pavlov. Cond. response bias0.30.40.91.00.10.70.7-0.20.7-0.6-0.70.7-0.90.2
Time in closed arm before self-admin0.30.31.2-0.1-0.1-0.6-0.40.1-0.80.20.8-0.30.81.1
Time in closed arm after self-admin0.30.30.9-0.40.0-0.6-0.50.4-0.40.70.40.71.00.1
Time in open arm before self-admin0.70.81.2-0.40.61.11.0-0.81.1-0.9-1.11.0-0.0-0.9
Time in open arm after self-admin0.91.02.1-0.40.81.51.2-1.21.1-1.4-1.10.3-0.3-0.1
Bone: periosteal estimation1.32.65.9-0.51.62.21.5-1.22.4-1.5-2.41.7-0.60.1
Bone: periosteal perimeter1.42.35.30.21.62.31.4-1.61.9-2.1-2.01.0-0.60.5
Bone: post-yield work1.72.47.9-1.21.21.41.0-0.42.4-0.3-2.42.8-0.10.1
Progressive ratio test 1 active lever presses0.40.41.6-1.10.6-0.00.6-0.5-0.1-0.10.20.10.71.3
Progressive ratio test 1 breakpoint0.40.41.6-1.10.5-0.10.6-0.4-0.1-0.10.20.10.71.3
Progressive ratio test 1 inactive lever presses0.80.92.00.5-1.2-1.3-1.01.3-0.81.40.8-0.4-0.40.6
Progressive ratio test 2 active lever presses0.80.81.8-0.1-0.7-1.3-1.00.9-1.01.31.0-1.0-0.30.3
Progressive ratio test 2 breakpoint0.40.50.9-0.6-0.2-0.9-0.70.3-0.90.71.0-0.90.40.6
Progressive ratio test 2 inactive lever presses0.60.72.2-0.6-0.5-1.3-1.01.0-0.61.50.6-0.3-0.10.3
Incentive Sensitization - Responses0.50.51.2-0.0-0.5-1.1-0.50.7-1.01.01.0-0.20.30.3
Incentive Sensitization - Breakpoint0.40.41.1-0.1-0.4-1.0-0.40.6-1.00.91.0-0.20.50.4
Sum of active levers in priming session hrs 5-60.80.82.0-0.90.90.81.1-0.70.8-0.6-0.81.40.60.7
Progressive ratio0.50.61.40.6-0.8-0.5-0.91.10.31.1-0.3-0.0-1.2-0.4
Food seeking constrained by brief footshock0.20.30.70.3-0.4-0.8-0.20.7-0.60.80.50.30.40.3
Seeking ratio, punishment vs. effort0.40.51.9-0.10.2-0.40.5-0.4-1.1-0.21.1-0.21.40.7
Retroperitoneal fat weight1.24.18.4-2.92.62.11.8-2.61.6-2.3-1.51.51.60.6
Reaction time number correct0.91.23.31.8-1.2-0.2-1.31.0-0.00.5-0.1-0.7-1.7-1.6
Reaction time mean minus median4.05.312.6-3.52.61.32.8-2.11.2-1.4-1.02.53.22.1
Reaction time mean minus median AUC3.74.812.6-3.52.51.32.4-2.01.3-1.2-1.12.32.92.1
Reaction time num false alarms2.02.88.52.5-1.7-0.6-2.11.6-0.11.0-0.0-1.6-2.9-1.4
Reaction time num false alarms AUC1.72.37.22.4-1.5-0.3-1.91.2-0.10.7-0.1-1.6-2.7-1.3
Reaction time trials correct on left0.91.23.31.8-1.2-0.2-1.31.0-0.00.5-0.1-0.7-1.7-1.6
Reaction time trials on left0.91.23.21.8-1.2-0.2-1.21.00.10.5-0.2-0.6-1.8-1.6
Reaction time mean1.21.63.9-1.71.20.81.7-0.71.2-0.4-1.22.01.11.3
Reaction time mean AUC0.91.23.1-1.40.90.51.5-0.50.9-0.1-0.91.81.11.4
Median of all reaction times0.40.62.0-0.80.40.41.0-0.10.90.1-0.91.40.30.8
Reaction time omissions1.31.83.4-1.61.31.51.3-1.11.8-1.0-1.81.70.3-0.2
Reaction time false alarm rate0.50.72.21.3-0.7-0.2-1.00.5-0.10.20.1-1.2-1.5-0.3
Reaction time premature initiation rate0.70.92.0-0.4-0.4-1.2-0.40.5-1.40.81.4-0.50.91.3
Reaction time premature initiations0.50.71.40.3-0.8-1.1-0.80.8-1.20.91.2-0.60.20.6
Std. dev. reaction times2.63.77.3-2.72.11.52.3-1.61.6-1.1-1.62.41.91.6
Reaction time trials completed0.91.23.21.8-1.2-0.2-1.21.00.10.5-0.2-0.6-1.8-1.6
Reaction time trials AUC0.71.13.21.7-1.1-0.0-1.10.80.20.3-0.3-0.5-1.8-1.5
Run reversals in cocaine runway, females4.54.46.4-2.22.42.12.5-2.51.4-2.3-1.31.92.11.9
Run reversals in cocaine runway, males0.70.72.4-1.40.70.30.8-0.10.90.3-0.91.60.50.1
Latency to leave start box in cocaine runway0.20.21.2-0.40.40.20.4-0.4-0.0-0.30.00.71.10.3
Latency to leave start box in cocaine runway, F0.10.10.7-0.50.20.10.3-0.10.20.1-0.20.80.60.2
Latency to leave start box in cocaine runway, M1.00.92.0-0.81.20.81.0-1.30.2-1.2-0.20.71.40.9
Std. dev. time between licks in bursts0.40.41.10.6-0.6-0.7-0.70.4-0.90.40.9-1.0-0.1-0.3
Total sessions with >9 infusions0.10.10.4-0.00.00.1-0.2-0.3-0.3-0.40.3-0.60.10.1
Short access day 1 total inactive lever presses0.80.91.71.2-1.3-1.1-0.70.9-1.20.81.2-0.8-0.20.4
Short access day 10 total inactive lever presses0.20.20.40.4-0.4-0.1-0.60.50.30.4-0.40.4-0.5-0.6
Short access day 1 total infusions0.70.81.4-1.21.01.00.8-1.10.8-1.0-0.70.60.60.5
Short access day 10 total infusions0.70.71.8-0.6-0.4-1.3-0.40.8-0.91.31.0-0.20.31.1
Short access total infusions0.30.30.7-0.5-0.2-0.8-0.60.3-0.70.70.8-0.70.20.6
Short access day 1 locomotion0.30.31.1-0.50.40.20.0-0.9-0.4-0.80.5-1.00.5-0.0
Short access day 10 total locomotion0.30.41.2-0.50.30.5-0.20.01.10.0-1.10.3-0.9-0.2
Short access total locomotion0.20.20.4-0.60.50.4-0.2-0.50.4-0.5-0.3-0.5-0.20.2
One hour access (0.3 mA shock)1.21.43.5-0.4-0.7-1.7-0.21.1-1.31.71.40.20.81.9
Compulsive drug intake1.11.23.20.7-1.2-1.6-0.51.6-0.91.80.90.60.00.7
One hour access (shock baseline)0.40.51.2-0.1-0.5-1.1-0.40.8-0.81.00.9-0.50.10.6
Social response proportion0.10.10.20.2-0.10.10.40.20.30.2-0.30.4-0.5-0.1
Social responses0.70.81.8-0.50.81.01.3-0.80.9-0.9-0.91.20.31.0
Social time0.91.13.10.6-0.7-0.3-0.61.51.01.4-1.11.0-1.8-0.9
Soleus weight0.31.02.2-0.91.20.61.0-1.5-0.4-1.40.5-0.41.31.0
Bone: stiffness2.13.49.1-1.21.62.31.3-1.23.0-1.3-3.02.0-0.9-0.7
Tibialis anterior weight4.515.327.1-5.25.13.94.2-4.63.1-4.0-2.93.33.41.9
Time to tail flick, vehicle, before self-admin1.21.23.70.30.51.10.00.11.8-0.2-1.90.4-1.9-0.8
Time to tail flick, vehicle, after self-admin3.94.17.82.5-2.0-1.7-2.22.4-1.02.10.9-1.9-2.8-1.9
Time to tail flick, test, before self-admin0.70.72.1-0.90.80.41.5-1.0-0.2-0.80.20.51.50.3
Time to tail flick, test, after self-admin1.51.62.91.5-1.7-1.2-1.51.2-1.11.01.1-1.7-0.9-0.3
Delta time to tail flick, vehicle, before/after SA6.96.99.82.6-3.0-3.1-2.82.8-2.92.82.8-2.6-1.3-1.3
Delta time to tail flick, test, before/after SA0.70.61.70.9-1.0-0.5-1.20.6-0.40.40.4-1.3-0.90.0
Tibia length0.20.62.00.20.30.9-0.1-0.21.2-0.4-1.20.0-1.4-0.4
Ambulatory time before self-admin2.62.74.1-1.62.01.81.7-1.91.4-1.9-1.41.51.11.4
Ambulatory time after self-admin1.82.03.2-0.81.81.61.7-1.61.0-1.8-1.01.41.11.3
Bone: tissue strength0.30.20.70.1-0.10.2-0.10.40.80.3-0.80.4-0.8-0.5
Total heroin consumption1.21.43.0-0.61.11.31.3-0.61.7-0.6-1.71.7-0.60.8
Bone: trabecular number2.03.15.31.3-1.7-2.3-2.12.2-1.72.31.6-1.5-1.1-0.9
Bone: trabecular spacing0.20.30.8-0.10.30.90.4-0.60.8-0.8-0.80.2-0.3-0.1
Bone: trabecular thickness1.01.22.20.8-1.1-1.5-1.11.1-1.51.21.4-0.50.40.3
Bone: trabecular tissue density2.94.17.7-0.82.02.82.0-1.92.6-2.3-2.72.0-0.01.1
Water consumed over 24 hours0.20.20.80.00.20.30.60.10.60.0-0.70.9-0.4-0.2
Number of responses in last shaping day1.41.52.4-1.31.61.51.1-1.61.2-1.5-1.10.50.60.4