Armc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Armc1 0.04 0.03 1.8e-03 0.01 0.01 0 0 7.3e-02 3.6e-02 2.7e-01 1.6e-01
2 NAcc gene expression Armc1 0.05 0.03 2.1e-07 0.04 0.04 0.02 0.04 2.3e-06 1.8e-06 2.9e-04 3.4e-06
3 LHb gene expression Armc1 0.32 0.15 4.4e-04 0.09 0.11 0.08 0.09 3.1e-03 1.4e-03 5.2e-03 3.6e-03
4 LHb alternative TSS NM_001106425.2 0.28 0.13 1.1e-03 -0.01 0.03 0 0.01 7.2e-01 8.4e-02 3.3e-01 1.8e-01
5 LHb alternative TSS XM_039101979.2 0.27 0.13 1.4e-03 -0.01 0.03 -0.01 0 8.2e-01 8.6e-02 9.3e-01 2.6e-01
6 Brain gene expression Armc1 0.04 0.03 1.6e-04 0.03 0.04 0.04 0.03 4.6e-04 2.5e-04 2.3e-04 3.7e-04
7 Brain mRNA stability Armc1 0.05 0.03 1.9e-04 0.03 0.02 0.01 0.02 3.8e-04 3.8e-03 1.7e-02 3.2e-03
8 PL gene expression Armc1 0.04 0.02 2.4e-05 0.04 0.04 0.03 0.03 8.7e-05 7.8e-05 3.2e-04 1.4e-04
9 BLA gene expression Armc1 0.14 0.08 6.3e-06 0.05 0.06 0.06 0.05 1.3e-03 5.5e-04 3.8e-04 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.32.23.01.51.61.4-1.71.71.5-1.31.51.1
Area under the delay curve0.10.10.3-0.3-0.4-0.4-0.10.1-0.50.1-0.2-0.1
BMI with tail2.58.511.5-3.1-3.4-3.33.0-3.0-2.92.9-2.6-1.8
BMI without tail2.16.38.3-2.7-2.9-2.72.3-2.3-2.72.3-2.5-2.2
Body weight2.510.813.6-3.2-3.7-3.23.5-3.4-3.43.2-3.5-2.3
Weight adjusted by age0.20.31.0-0.4-0.6-0.20.5-0.4-0.50.5-1.0-0.5
Bone surface0.00.00.10.10.20.1-0.20.20.2-0.30.30.2
Bone volume0.00.00.00.10.20.2-0.20.20.2-0.10.20.0
Breakpoint value in progressive ratio session0.20.31.2-0.6-0.3-0.50.2-0.3-0.10.5-0.1-1.1
Number of licking bursts1.11.92.8-1.3-1.4-1.11.4-1.4-1.11.7-1.6-1.2
Context. condit. distance diff. score0.10.20.80.1-0.40.10.00.1-0.60.5-0.90.1
Locomotion velocity, session 10.20.20.7-0.5-0.6-0.50.1-0.1-0.90.3-0.4-0.4
Locomotion distance, session 10.10.20.4-0.2-0.2-0.70.4-0.50.2-0.30.60.6
Locomotion velocity, session 22.02.34.0-1.8-1.8-1.91.2-1.2-2.01.2-1.0-1.3
Locomotion distance, session 20.20.20.7-0.2-0.3-0.60.4-0.50.2-0.20.50.9
Locomotion velocity, session 31.21.31.8-1.2-1.4-1.31.0-1.0-1.21.3-1.1-0.7
Locomotion distance, session 30.80.81.5-0.9-1.1-0.90.5-0.5-1.01.2-1.0-0.8
Stereotopy head waving bouts, day 30.20.30.60.60.60.7-0.40.50.7-0.50.20.4
Stereotopy head waving duration, day 30.40.51.10.60.90.7-0.30.31.0-0.70.80.5
Locomotion velocity, session 72.52.73.91.91.81.7-1.11.21.8-1.71.42.0
Locomotion distance, session 72.63.34.82.12.22.2-1.61.71.9-1.51.51.6
Stereotopy head waving bouts, day 70.60.61.0-0.8-1.0-0.80.6-0.6-0.90.7-1.0-0.6
Stereotopy head waving duration, day 70.30.40.5-0.7-0.7-0.60.4-0.4-0.60.6-0.6-0.7
Locomotion velocity, session 81.01.32.6-1.1-1.4-1.40.9-0.9-1.61.0-0.9-0.5
Locomotion distance, session 81.11.62.4-1.2-1.6-1.41.3-1.2-1.51.3-1.3-0.5
Degree of sensitization distance4.44.56.72.12.62.2-1.61.62.5-2.32.31.7
Degree of sensitization stereotypy2.02.23.3-1.4-1.8-1.51.1-1.1-1.81.5-1.7-1.2
Conditioned locomotion2.02.33.41.61.41.2-1.41.41.4-1.71.61.8
Cocaine response after cond. corrected0.20.20.60.30.60.8-0.40.40.1-0.10.0-0.6
Cocaine response after cond. not corrected0.20.20.60.30.60.8-0.40.40.10.0-0.0-0.6
Cocaine response before conditioning0.20.20.50.40.50.3-0.20.10.6-0.50.60.7
Saline control response0.70.91.9-1.1-1.0-1.11.4-1.4-0.50.6-0.7-0.5
Bone: connectivity density1.93.04.71.51.81.3-2.11.91.7-1.72.21.0
Bone: cortical apparent density0.60.91.9-0.8-1.0-0.70.2-0.2-1.40.9-1.0-1.3
Bone: cortical area0.50.72.3-0.2-0.8-0.21.2-1.1-0.80.6-1.50.4
Bone: cortical porosity0.70.72.50.70.70.40.0-0.01.2-0.80.91.6
Bone: cortical porosity0.40.42.30.60.40.30.00.00.7-0.60.51.5
Bone: cortical thickness0.50.83.31.20.51.1-0.00.20.3-0.7-0.51.8
Bone: cortical thickness0.30.30.5-0.3-0.7-0.50.7-0.6-0.70.0-0.70.5
Bone: cortical tissue density0.81.12.4-1.0-1.1-0.90.2-0.2-1.51.1-1.1-1.6
Condit. Reinf. active minus inactive responses0.20.20.5-0.4-0.3-0.60.7-0.70.2-0.30.30.4
Condit. Reinf. active-inactive response ratio0.10.10.3-0.10.1-0.20.2-0.30.4-0.40.50.3
Condit. Reinf. active responses0.20.20.7-0.6-0.5-0.80.5-0.6-0.2-0.40.10.2
Condit. Reinf. inactive responses0.50.61.0-0.9-0.9-1.00.7-0.7-0.80.2-0.5-0.6
Incentive salience index mean0.30.30.7-0.7-0.6-0.80.8-0.9-0.20.1-0.2-0.2
Condit. Reinf. lever presses0.40.61.2-1.0-0.8-0.90.4-0.5-0.70.5-0.5-1.1
Condit. Reinf. active minus inactive responses0.10.10.30.0-0.4-0.30.3-0.3-0.20.3-0.40.6
Condit. Reinf. active-inactive response ratio0.10.10.20.2-0.3-0.2-0.20.2-0.30.2-0.10.4
Condit. Reinf. active responses0.10.20.70.1-0.1-0.10.6-0.60.3-0.0-0.10.8
Condit. Reinf. inactive responses0.20.21.0-0.1-0.10.01.0-0.90.2-0.0-0.40.3
Condit. Reinf. lever presses0.10.20.80.40.50.50.0-0.00.9-0.30.30.4
Condit. Reinf. lever reinforcers received0.10.20.60.1-0.1-0.10.6-0.60.2-0.0-0.10.8
Conditioned reinforcement - actives0.10.20.60.40.50.3-0.40.30.8-0.50.70.3
Conditioned reinforcement - inactives0.10.10.4-0.10.30.2-0.50.40.2-0.10.2-0.6
Conditioned locomotion0.20.31.6-0.3-0.3-0.2-0.10.1-0.30.7-0.5-1.3
Patch foraging indifference point 0 sec0.20.41.2-0.3-0.40.1-0.10.1-0.70.8-1.1-1.1
Patch foraging indifference point AUC0.20.41.20.40.2-0.1-0.50.40.0-0.80.81.1
Delay disc. indifference point, 0s delay0.10.10.30.1-0.3-0.20.4-0.3-0.20.0-0.30.5
Delay disc. indifference point, 16s delay0.40.40.80.60.40.2-0.70.70.4-0.90.80.8
Delay disc. indifference point, 2s delay0.10.10.3-0.0-0.20.0-0.20.2-0.50.3-0.5-0.1
Delay disc. indifference point, 24s delay1.51.72.21.31.21.2-1.51.51.1-1.51.11.3
Delay disc. indifference point, 4s delay1.81.93.2-1.6-1.6-1.81.0-1.1-1.61.3-0.9-1.3
Delay disc. indifference point, 8s delay0.10.10.3-0.4-0.4-0.5-0.10.0-0.50.2-0.1-0.5
Indifference point function ln k0.71.34.8-1.2-0.8-0.60.4-0.4-0.91.4-1.0-2.2
Indifference point function log k0.71.34.8-1.2-0.8-0.60.4-0.4-0.91.4-1.0-2.2
Patch foraging total patch changes 0 sec0.40.82.3-0.6-0.7-0.20.1-0.1-1.01.1-1.3-1.5
Patch foraging total patch changes 12 sec0.00.10.20.3-0.00.1-0.20.3-0.1-0.2-0.10.4
Patch foraging total patch changes 18 sec0.10.10.2-0.2-0.5-0.50.2-0.2-0.4-0.2-0.20.2
Patch foraging total patch changes 24 sec0.10.30.60.40.40.2-0.70.60.1-0.80.60.4
Patch foraging total patch changes 6 sec0.40.60.9-0.9-0.9-0.90.4-0.5-1.00.7-0.7-0.9
Patch foraging time to switch 0 sec0.00.10.2-0.1-0.1-0.10.5-0.40.10.2-0.0-0.1
Patch foraging water rate 0 sec0.10.30.9-0.3-0.4-0.3-0.50.4-0.90.5-0.4-0.8
Patch foraging water rate 12 sec0.20.51.10.60.70.4-0.40.40.8-0.90.91.1
Patch foraging water rate 18 sec0.10.20.30.30.40.3-0.30.30.4-0.60.50.3
Patch foraging water rate 24 sec0.30.50.90.60.50.4-1.00.90.2-1.00.70.5
Patch foraging water rate 6 sec0.50.72.4-0.7-0.6-0.30.3-0.3-0.91.0-1.1-1.5
Seeking ratio, delayed vs. immediate footshock3.64.46.92.42.42.6-2.42.51.7-1.81.40.9
Distance traveled before self-admin5.67.38.8-2.7-3.0-2.62.8-2.8-2.72.8-2.8-2.1
Distance traveled after self-admin7.59.211.1-3.1-3.0-2.62.9-2.8-3.03.3-3.3-3.2
Extensor digitorum longus weight6.023.831.0-5.4-5.6-5.44.5-4.5-5.34.5-4.4-4.2
Bone: elastic displacement2.83.24.32.01.61.7-2.12.11.5-1.91.41.7
Bone: elastic work0.91.21.91.21.01.2-1.31.40.8-1.30.60.8
Bone: endosteal estimation2.14.57.2-2.4-2.2-2.42.7-2.7-1.62.0-1.4-1.5
Bone: endosteal perimeter1.83.85.4-1.8-1.8-1.32.2-2.1-1.72.3-2.3-1.7
Epididymis fat weight2.07.010.4-2.5-2.9-2.22.6-2.5-3.22.6-3.1-2.0
Delta time in closed arm before/after self-admin0.30.20.70.30.3-0.0-0.20.20.7-0.40.80.7
Delta time in open arm before/after self-admin0.10.10.40.30.10.6-0.20.3-0.30.4-0.6-0.2
Diff in mean of infusions in LGA sessions0.10.20.40.30.40.2-0.40.30.6-0.50.60.2
Delay discount exponential model param0.10.10.20.30.40.40.1-0.10.5-0.20.20.2
Extinction: sum of active levers before priming0.10.10.20.40.40.4-0.40.40.3-0.00.30.1
Active lever presses in extinction session 62.12.14.8-1.4-1.4-1.52.2-2.1-0.71.2-0.9-0.2
Bone: final force1.32.14.5-1.3-1.5-1.42.1-2.1-1.11.0-1.3-0.1
Bone: final moment1.21.94.5-1.2-1.4-1.32.1-2.0-1.00.9-1.3-0.0
Food consumed during 24 hour testing period4.15.77.3-2.7-2.6-2.62.5-2.6-2.12.2-2.0-2.0
Glucose0.71.12.1-1.0-1.1-1.11.5-1.4-0.61.0-0.9-0.1
Heart weight0.40.61.3-0.9-0.9-0.80.3-0.3-0.90.5-0.7-1.1
Delay discount hyperbolic model param0.20.20.40.40.60.5-0.10.10.6-0.40.40.3
Intermittent access intake day 1-15 change0.20.31.0-0.7-0.7-1.00.5-0.6-0.50.40.1-0.2
Intermittent access intake escalation0.20.30.9-0.7-0.7-1.00.5-0.5-0.50.40.0-0.3
Intermittent access intake escalation 20.30.30.7-0.6-0.6-0.80.6-0.6-0.50.5-0.0-0.1
Intermitt. access day 1 inactive lever presses0.20.71.5-1.2-0.8-1.20.9-1.1-0.50.30.0-0.4
Intermitt. access day 15 inactive lever presses0.10.31.4-0.00.3-0.3-0.20.00.6-0.31.20.7
Intermitt. access escalation Index0.30.40.90.20.90.6-0.40.30.9-0.80.9-0.5
Intermittent access day 1 total infusions0.10.20.90.00.2-0.2-0.40.30.4-0.90.80.0
Intermittent access day 15 total infusions0.30.41.9-0.10.1-0.6-0.30.10.5-1.01.40.6
Intermittent access terminal intake (last 3 days)0.40.62.3-0.8-0.6-1.50.3-0.50.0-0.31.10.2
Intermittent access total infusions0.60.72.8-0.00.2-0.6-0.50.30.7-1.31.70.5
Intermittent access day 1 locomotion0.10.10.2-0.1-0.4-0.3-0.10.1-0.40.1-0.3-0.3
Intermittent access day 15 total locomotion0.20.30.9-0.5-0.6-0.60.2-0.2-0.50.7-0.4-1.0
Intermittent access total locomotion0.20.20.8-0.4-0.5-0.40.0-0.1-0.50.5-0.3-0.9
Intermittent access standard deviation0.30.51.6-0.9-0.8-1.20.8-0.8-0.50.30.10.1
Left kidney weight0.20.72.0-0.6-0.9-0.40.2-0.2-1.00.8-1.4-1.3
Right kidney weight0.52.45.2-1.3-1.8-1.11.3-1.2-1.71.5-2.3-1.4
Cocaine induced anxiety0.10.10.60.2-0.0-0.00.3-0.30.30.00.00.8
Post-drug Anxiety0.30.31.20.40.30.10.3-0.30.6-0.30.61.1
Baseline Anxiety0.10.10.4-0.5-0.3-0.40.2-0.2-0.40.3-0.0-0.6
Tail length0.20.92.2-0.8-0.9-0.40.7-0.6-1.10.7-1.5-1.3
Length with tail0.73.25.0-1.6-1.8-1.32.0-1.9-1.71.8-2.2-1.6
Length without tail0.92.94.1-1.5-1.8-1.41.9-1.8-1.81.9-2.0-1.0
Times rat made contact with spout4.14.76.9-2.0-2.0-1.42.4-2.3-1.82.6-2.6-2.0
Lifetime Intake0.50.62.50.00.2-0.6-0.50.30.6-1.31.60.5
Liver weight, left1.22.04.0-1.5-1.5-1.62.0-2.0-0.81.2-1.0-0.4
Liver weight, right4.88.39.9-3.1-2.8-2.73.1-3.1-2.82.7-2.6-2.9
Locomotor activity0.61.01.7-1.1-1.1-1.11.3-1.3-0.70.8-0.9-0.5
Locomotor testing distance0.81.42.7-1.1-1.2-1.01.6-1.6-0.91.0-1.3-0.4
Locomotor testing rearing0.10.20.60.20.20.20.8-0.70.4-0.3-0.10.8
Locomotion in novel chamber0.30.30.6-0.4-0.6-0.40.7-0.6-0.60.8-0.8-0.2
Locomotion in novel chamber post-restriction0.40.71.70.60.70.3-0.50.41.0-0.81.31.2
Fecal boli incidents, locomotor time 10.50.71.7-0.20.1-0.71.0-1.00.8-0.61.21.3
Change in fecal boli incidents, locomotor task1.81.84.11.91.32.0-1.51.70.8-0.7-0.10.7
Time >=10cm from walls, locomotor time 10.30.30.40.60.70.7-0.20.20.7-0.60.40.6
Bouts of movement, locomotor time 10.40.41.10.50.50.2-1.11.00.4-0.60.90.2
Total resting periods, locomotor time 10.50.61.50.50.60.3-1.21.10.4-0.71.00.1
Rest time, locomotor task time 10.60.72.3-1.0-0.8-1.50.9-1.0-0.30.20.6-0.0
Distance moved, locomotor task time 10.30.51.30.20.31.00.10.0-0.00.7-1.1-1.1
Vertical activity count, locomotor time 10.40.93.1-0.4-0.20.50.4-0.2-0.61.2-1.5-1.8
Time >=10cm from walls, locomotor time 20.40.61.31.00.80.9-0.30.40.9-0.50.41.1
Bouts of movement, locomotor time 20.30.41.40.40.30.1-1.21.10.1-0.70.80.1
Total resting periods, locomotor time 20.20.41.10.20.1-0.1-1.11.0-0.0-0.70.70.1
Rest time, locomotor task time 20.30.41.9-0.5-0.2-1.10.2-0.40.4-0.41.4-0.0
Distance moved, locomotor task time 20.30.41.50.70.81.2-0.20.30.6-0.1-0.30.2
Vertical activity count, locomotor time 20.81.22.7-1.2-0.7-0.71.1-1.1-0.71.3-0.9-1.6
Light reinforcement 10.41.01.8-0.9-1.1-0.80.8-0.8-1.30.8-1.3-0.9
Light reinforcement 22.74.110.0-1.5-1.7-0.51.1-1.0-2.62.2-3.2-2.8
Bone: marrow area2.14.57.2-2.4-2.1-2.42.6-2.7-1.62.0-1.4-1.5
Bone: maximum diameter0.81.53.3-0.9-1.2-0.61.7-1.5-1.11.2-1.8-0.5
Bone: maximum force1.62.96.3-1.7-1.7-1.82.5-2.5-1.21.3-1.2-0.4
Bone: maximum moment1.52.66.1-1.6-1.6-1.72.5-2.4-1.01.2-1.2-0.2
Mean time between licks in bursts0.40.91.6-1.3-0.8-1.20.7-0.9-0.91.0-0.1-1.1
Mean num. licks in bursts0.00.00.10.10.20.20.2-0.20.1-0.10.10.2
Cd content in liver1.71.93.7-1.6-1.5-1.91.7-1.8-0.91.2-0.5-0.6
Co content in liver1.41.73.1-1.3-1.1-0.91.8-1.7-0.91.5-1.3-0.8
Cu content in liver0.20.20.50.60.60.7-0.20.30.60.10.20.3
Fe content in liver0.20.21.20.50.20.40.4-0.30.4-0.2-0.11.1
K content in liver1.01.01.51.01.21.2-1.11.10.9-1.00.70.4
Mg content in liver0.80.81.50.91.01.1-1.21.20.7-0.50.60.0
Mn content in liver0.00.00.1-0.0-0.0-0.1-0.30.3-0.10.00.10.1
Na content in liver0.30.31.4-0.2-0.50.00.2-0.1-0.80.6-1.2-0.3
Rb content in liver0.91.02.11.21.11.1-0.20.31.4-0.90.91.3
Se content in liver0.10.10.90.40.20.40.1-0.00.20.0-0.10.9
Sr content in liver1.31.12.10.71.00.6-1.41.21.1-1.01.40.6
Zn content in liver0.20.20.30.30.60.5-0.60.50.50.00.4-0.4
Bone: minimum diameter0.71.22.2-1.0-1.0-0.71.5-1.4-0.91.3-1.3-0.8
Time in familiar zone, hab. session 10.20.20.6-0.10.40.20.3-0.30.8-0.10.4-0.4
Time in novel zone, hab. session 10.20.20.7-0.2-0.6-0.4-0.10.1-0.90.3-0.6-0.1
Total zone transitions, hab. session 10.10.10.30.2-0.0-0.0-0.60.5-0.3-0.20.10.3
Total locomotion distance, hab. session 10.10.10.30.3-0.00.1-0.50.5-0.3-0.2-0.00.3
Locomotion velocity, hab. session 10.10.10.20.1-0.2-0.0-0.50.5-0.40.1-0.20.0
Time in familiar zone, hab. session 20.30.30.80.40.90.8-0.30.30.8-0.40.5-0.2
Time in novel zone, hab. session 20.20.20.80.30.1-0.1-0.30.20.4-0.60.60.9
Total zone transitions, hab. session 20.20.30.5-0.5-0.7-0.60.3-0.3-0.60.7-0.5-0.3
Total locomotion distance, hab. session 20.00.00.00.1-0.1-0.1-0.10.1-0.00.1-0.10.2
Locomotion velocity, hab. session 20.00.00.10.1-0.20.0-0.20.3-0.20.3-0.30.0
Novel to familiar place preference ratio2.02.13.61.61.41.1-1.41.41.3-1.41.51.9
Novelty place preference1.82.03.01.51.31.1-1.51.51.2-1.41.41.7
Time in novel zone, NPP test1.41.52.51.31.11.0-1.21.21.1-1.21.31.6
Total zone transitions, NPP test0.10.10.40.0-0.1-0.30.0-0.10.3-0.10.40.7
Total locomotion distance, NPP test0.00.00.20.1-0.0-0.10.1-0.10.20.20.10.4
Locomotion velocity, NPP test0.20.30.80.70.50.4-0.50.50.5-0.30.60.9
Intraocular pressure0.60.91.6-1.0-1.1-1.20.8-0.8-1.30.7-0.6-0.6
Delta distance traveled before/after self-admin0.00.10.20.10.10.3-0.30.3-0.10.1-0.2-0.4
Delta ambulatory time before/after self-admin0.50.61.40.80.81.0-1.11.20.4-0.50.20.1
Parametrial fat weight3.37.99.9-2.7-3.0-2.42.9-2.8-3.03.0-3.1-2.1
Pavlov. Cond. lever latency0.30.31.00.90.50.7-0.30.40.3-0.30.01.0
Pavlov. Cond. magazine entry latency0.50.62.2-1.2-0.6-1.10.2-0.4-0.30.30.1-1.5
Pavlov. Cond. change in total contacts2.62.84.4-2.1-1.8-2.01.4-1.5-1.51.4-1.1-1.9
Pavlov. Cond. index score1.31.63.8-1.8-1.2-1.60.8-0.9-1.01.0-0.5-1.9
Pavlov. Cond. latency score0.91.22.4-1.5-1.0-1.50.8-1.0-0.70.7-0.3-1.5
Pavlov. Cond. lever contacts0.60.72.4-1.2-0.7-1.00.2-0.3-0.60.5-0.1-1.5
Pavlov. Cond. magazine entry number1.41.85.11.91.31.6-0.60.81.1-0.90.62.3
Pavlov. Cond. intertrial magazine entries0.60.71.41.00.60.9-1.01.00.2-1.20.20.9
Pavlov. Cond. lever-magazine prob. diff.1.92.35.2-2.1-1.5-1.81.0-1.1-1.31.3-0.7-2.3
Pavlov. Cond. response bias1.51.95.6-1.8-1.3-1.60.5-0.6-1.30.9-0.6-2.4
Pavlov. Cond. lever latency0.10.20.5-0.4-0.3-0.7-0.40.2-0.5-0.20.6-0.2
Pavlov. Cond. magazine entry latency0.20.20.7-0.6-0.3-0.30.4-0.4-0.30.4-0.4-0.8
Pavlov. Cond. change in total contacts0.10.20.50.50.20.50.3-0.20.4-0.2-0.30.7
Pavlov. Cond. index score0.20.20.7-0.3-0.30.00.6-0.5-0.30.5-0.8-0.5
Pavlov. Cond. latency score0.10.20.6-0.3-0.30.00.6-0.5-0.30.4-0.8-0.4
Pavlov. Cond. lever contacts0.10.20.60.40.30.70.3-0.20.40.1-0.60.2
Pavlov. Cond. magazine entry number0.20.20.50.30.30.2-0.70.60.2-0.40.50.3
Pavlov. Cond. intertrial magazine entries0.30.50.70.70.70.5-0.80.80.6-0.80.80.6
Pavlov. Cond. lever-magazine prob. diff.0.30.40.9-0.4-0.4-0.10.7-0.6-0.50.6-0.9-0.6
Pavlov. Cond. response bias0.10.10.50.10.00.40.5-0.40.20.3-0.7-0.1
Time in closed arm before self-admin0.10.10.5-0.10.10.1-0.60.5-0.0-0.10.1-0.7
Time in closed arm after self-admin0.20.20.4-0.10.50.2-0.40.30.7-0.30.6-0.5
Time in open arm before self-admin0.50.51.0-0.7-0.7-0.61.0-1.0-0.70.6-0.7-0.4
Time in open arm after self-admin0.80.92.1-0.5-0.9-0.40.9-0.8-1.31.1-1.5-0.5
Bone: periosteal estimation1.53.15.9-1.7-1.8-1.52.4-2.3-1.41.7-1.8-0.8
Bone: periosteal perimeter1.22.04.8-1.0-1.3-0.61.8-1.6-1.31.5-2.2-0.7
Bone: post-yield work2.13.16.7-2.1-1.6-2.12.5-2.6-0.91.3-0.6-0.8
Progressive ratio test 1 active lever presses0.30.31.2-0.6-0.8-1.10.5-0.5-0.5-0.2-0.00.2
Progressive ratio test 1 breakpoint0.30.31.2-0.6-0.8-1.10.5-0.5-0.5-0.20.00.2
Progressive ratio test 1 inactive lever presses0.60.91.70.70.90.6-0.90.80.9-1.31.20.9
Progressive ratio test 2 active lever presses0.20.20.50.30.0-0.2-0.70.60.1-0.70.60.5
Progressive ratio test 2 breakpoint0.10.20.40.2-0.0-0.2-0.60.60.0-0.60.50.3
Progressive ratio test 2 inactive lever presses0.20.31.3-0.10.1-0.5-0.20.00.5-0.61.10.5
Incentive Sensitization - Responses0.20.30.70.30.40.2-0.80.80.4-0.40.80.0
Incentive Sensitization - Breakpoint0.20.20.70.20.30.1-0.80.70.3-0.30.7-0.1
Sum of active levers in priming session hrs 5-60.70.71.0-0.8-0.7-0.60.8-0.8-0.81.0-0.8-0.9
Progressive ratio0.30.51.30.50.60.3-0.00.00.9-1.01.01.1
Food seeking constrained by brief footshock0.20.30.70.30.70.5-0.60.50.6-0.30.8-0.0
Seeking ratio, punishment vs. effort0.20.20.9-0.00.10.3-0.60.6-0.30.5-0.3-0.9
Retroperitoneal fat weight1.04.26.4-2.2-2.4-2.21.7-1.8-2.51.9-2.0-1.5
Reaction time number correct0.81.42.31.41.41.5-0.50.61.4-1.30.71.5
Reaction time mean minus median3.07.510.6-3.2-2.8-3.12.0-2.2-2.83.1-1.8-3.3
Reaction time mean minus median AUC2.87.010.2-3.2-2.8-3.22.0-2.2-2.72.8-1.6-2.9
Reaction time num false alarms2.23.16.62.11.81.8-0.80.92.1-1.81.32.6
Reaction time num false alarms AUC1.72.65.42.01.61.8-0.70.91.9-1.61.02.3
Reaction time trials correct on left0.81.42.31.41.41.5-0.50.61.4-1.30.71.5
Reaction time trials on left0.71.42.31.41.31.4-0.40.51.4-1.30.71.5
Reaction time mean1.32.13.0-1.7-1.3-1.71.5-1.6-1.31.5-0.6-1.4
Reaction time mean AUC0.91.42.2-1.5-1.0-1.41.2-1.3-1.01.3-0.3-1.3
Median of all reaction times0.40.51.0-0.9-0.5-0.90.9-1.0-0.50.60.0-0.6
Reaction time omissions1.01.52.8-1.4-1.2-1.41.6-1.7-0.81.0-0.7-0.7
Reaction time false alarm rate0.50.81.71.10.81.0-0.50.61.0-0.80.41.3
Reaction time premature initiation rate0.30.41.30.40.50.3-1.11.00.2-0.60.8-0.2
Reaction time premature initiations0.40.81.20.80.90.8-1.11.10.7-1.00.90.4
Std. dev. reaction times2.85.27.3-2.7-2.3-2.62.1-2.2-2.22.4-1.4-2.3
Reaction time trials completed0.71.42.31.41.31.4-0.40.51.4-1.30.71.5
Reaction time trials AUC0.61.12.01.21.11.3-0.20.41.2-1.10.51.4
Run reversals in cocaine runway, females4.94.86.8-2.2-2.2-1.71.8-1.7-2.32.4-2.5-2.6
Run reversals in cocaine runway, males1.01.12.1-1.3-1.0-1.51.2-1.3-0.50.7-0.0-0.8
Latency to leave start box in cocaine runway0.30.31.4-0.7-0.3-0.30.3-0.3-0.30.5-0.4-1.2
Latency to leave start box in cocaine runway, F0.10.10.3-0.5-0.1-0.40.3-0.30.00.10.1-0.6
Latency to leave start box in cocaine runway, M0.20.20.9-0.4-0.3-0.10.3-0.3-0.40.6-0.6-0.9
Std. dev. time between licks in bursts0.30.40.70.70.60.6-0.80.80.6-0.60.50.6
Total sessions with >9 infusions0.30.41.10.70.50.5-0.30.30.5-1.00.50.7
Short access day 1 total inactive lever presses0.91.22.21.21.21.5-1.41.50.7-1.00.30.4
Short access day 10 total inactive lever presses0.00.00.10.00.20.10.2-0.20.20.00.10.3
Short access day 1 total infusions0.10.10.5-0.2-0.4-0.20.1-0.1-0.70.0-0.6-0.3
Short access day 10 total infusions0.20.31.20.10.2-0.3-0.10.00.7-1.11.00.4
Short access total infusions0.20.21.10.10.1-0.3-0.20.10.3-1.00.70.5
Short access day 1 locomotion0.20.30.70.5-0.10.5-0.50.6-0.6-0.2-0.80.3
Short access day 10 total locomotion0.20.30.9-0.3-0.6-0.50.9-0.9-0.20.2-0.40.1
Short access total locomotion0.10.20.7-0.1-0.5-0.20.3-0.2-0.6-0.0-0.8-0.2
One hour access (0.3 mA shock)0.30.41.5-0.20.4-0.3-0.70.50.6-0.51.2-0.5
Compulsive drug intake0.20.20.70.10.60.3-0.50.40.6-0.50.80.0
One hour access (shock baseline)0.71.03.00.60.90.2-1.00.91.2-1.31.70.6
Social response proportion0.10.10.1-0.1-0.1-0.20.3-0.4-0.00.40.10.3
Social responses0.60.81.2-0.8-0.8-0.61.0-1.0-0.81.1-0.9-0.8
Social time0.50.71.6-0.00.3-0.40.8-0.80.9-0.81.31.2
Soleus weight0.20.61.7-0.4-0.8-0.3-0.40.4-1.30.4-1.2-1.1
Bone: stiffness2.33.88.0-1.9-1.9-2.02.8-2.8-1.41.6-1.4-0.4
Tibialis anterior weight6.120.727.6-4.9-5.3-4.93.8-3.9-5.14.4-4.3-4.1
Time to tail flick, vehicle, before self-admin0.80.82.1-0.6-0.7-1.01.4-1.40.10.5-0.00.9
Time to tail flick, vehicle, after self-admin3.14.18.52.21.81.4-1.61.62.3-1.82.32.9
Time to tail flick, test, before self-admin0.20.20.9-0.4-0.4-0.3-0.40.3-0.70.3-0.3-0.9
Time to tail flick, test, after self-admin1.61.62.61.11.10.8-1.21.21.4-1.61.51.3
Delta time to tail flick, vehicle, before/after SA6.86.57.72.82.62.4-2.72.72.4-2.52.42.4
Delta time to tail flick, test, before/after SA0.60.61.40.80.70.5-0.70.60.9-0.80.81.2
Tibia length0.10.31.0-0.3-0.6-0.51.0-0.9-0.10.2-0.50.4
Ambulatory time before self-admin4.46.67.5-2.6-2.7-2.42.7-2.7-2.52.7-2.6-2.1
Ambulatory time after self-admin3.33.95.0-2.0-2.0-1.71.8-1.7-2.02.2-2.2-2.2
Bone: tissue strength0.20.20.4-0.10.0-0.20.6-0.60.50.10.40.6
Total heroin consumption0.60.71.1-0.9-0.8-0.90.9-0.9-0.61.1-0.6-0.7
Bone: trabecular number1.32.13.71.41.41.0-1.51.41.6-1.31.91.5
Bone: trabecular spacing0.10.20.4-0.2-0.4-0.30.6-0.5-0.4-0.1-0.50.3
Bone: trabecular thickness0.60.71.10.61.10.9-1.01.00.9-0.70.9-0.2
Bone: trabecular tissue density2.33.46.1-1.6-1.6-1.22.5-2.3-1.42.0-2.1-1.3
Water consumed over 24 hours0.30.40.9-0.7-0.6-0.71.0-1.00.00.8-0.3-0.3
Number of responses in last shaping day0.10.10.20.3-0.10.2-0.40.4-0.40.3-0.4-0.0