Hub : Genes

Syt17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA isoform ratio XM_017588770.3 0.04 0.03 3.9e-03 0.03 0.02 0.02 0.02 1.1e-03 1.3e-02 7.7e-03 5.8e-03
2 pVTA intron excision ratio chr1_182191400_182195689 0.05 0.03 6.6e-04 0.02 0.02 0.01 0.02 4.7e-03 4.5e-03 5.9e-02 1.8e-02
3 pVTA intron excision ratio chr1_182191405_182195689 0.05 0.03 3.5e-04 0.03 0.04 0.04 0.03 1.5e-03 7.5e-04 7.9e-04 1.6e-03
4 PL isoform ratio XM_006230104.2 0.04 0.03 8.8e-05 0.03 0.02 0.03 0.02 5.2e-04 9.9e-04 5.9e-04 3.6e-03
5 Liver gene expression Syt17 0.05 0.03 3.1e-05 0.02 0.02 0.02 0.01 1.5e-03 2.5e-03 2.8e-03 1.3e-02
6 PL intron excision ratio chr1_182191405_182191628 0.02 0.02 9.7e-03 0.01 0.01 0 0.01 4.3e-02 7.6e-03 1.3e-01 3.1e-02
7 Brain gene expression Syt17 0.2 0.09 8.9e-13 0.11 0.13 0.13 0.14 2.2e-10 1.8e-12 8.4e-12 7.3e-13
8 PL intron excision ratio chr1_182191400_182191628 0.03 0.02 3.2e-04 0.01 0.02 0.01 0.01 9.8e-03 1.8e-03 5.0e-02 1.4e-02
9 BLA isoform ratio XM_006230104.2 0.05 0.04 7.7e-03 -0 0.02 -0 0 5.1e-01 3.2e-02 4.6e-01 2.3e-01
10 IC mRNA stability Syt17 0.13 0.08 3.2e-04 0.07 0.07 0.06 0.07 4.8e-04 6.5e-04 1.0e-03 9.1e-04
11 Brain isoform ratio XM_006230104.2 0.04 0.02 2.3e-03 0.02 0.02 0.01 0.01 3.5e-03 7.7e-03 4.0e-02 2.2e-02
12 Adipose mRNA stability Syt17 0.05 0.03 2.1e-04 0.04 0.02 0.02 0.02 8.5e-05 2.7e-03 1.1e-03 8.8e-04
13 OFC mRNA stability Syt17 0.82 0.09 6.7e-16 0.41 0.37 0.31 0.33 7.2e-11 1.4e-09 3.1e-08 9.7e-09
14 Brain alternative TSS XM_017588772.2 0.04 0.03 4.2e-03 0.03 0.01 0.01 0.02 1.5e-03 1.3e-02 3.3e-02 9.6e-03
15 Brain alternative TSS XM_017588772.2 0.04 0.03 3.7e-03 0.03 0.01 0.01 0.02 8.9e-04 1.2e-02 6.0e-02 9.1e-03
16 NAcc gene expression Syt17 0.06 0.04 1.5e-08 0.06 0.05 0.06 0.06 1.7e-09 4.8e-08 5.2e-09 5.8e-09
17 LHb gene expression Syt17 0.18 0.11 4.5e-03 0.05 0.07 0.07 0.04 2.7e-02 1.1e-02 1.0e-02 3.5e-02
18 pVTA gene expression Syt17 0.09 0.05 1.8e-06 0.08 0.06 0.07 0.07 6.0e-07 1.2e-05 2.8e-06 5.6e-06
19 BLA isoform ratio XM_017588770.3 0.06 0.04 5.5e-03 0.05 0.02 0.02 0.04 9.4e-04 2.4e-02 2.5e-02 2.1e-03
20 PL mRNA stability Syt17 0.1 0.05 4.2e-09 0.06 0.08 0.07 0.07 7.6e-07 7.8e-09 4.9e-08 6.4e-08
21 BLA gene expression Syt17 0.08 0.05 3.9e-03 0 0.02 0.03 0 3.1e-01 3.3e-02 8.7e-03 2.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.71.23.41.6-1.61.5-1.61.31.51.9-1.3-1.0-1.0-0.9-0.8-0.8-0.8-0.80.80.10.3-0.4-0.2-0.1
Area under the delay curve0.20.20.8-0.20.6-0.70.2-0.80.10.30.10.3-0.3-0.7-0.2-0.3-0.2-0.20.4-0.1-0.1-0.3-0.60.9
BMI with tail2.68.823.74.9-4.64.7-4.04.03.43.1-3.5-3.4-2.2-2.0-1.9-1.8-1.9-1.91.92.22.52.0-0.3-0.5
BMI without tail3.811.730.65.5-5.45.3-4.84.74.34.1-4.1-3.6-2.7-2.5-2.1-2.0-2.1-2.11.92.12.01.9-0.1-0.5
Body weight1.56.721.44.6-4.34.2-3.73.73.33.3-3.1-2.6-1.7-1.4-1.3-1.4-1.4-1.41.41.21.40.60.2-0.8
Weight adjusted by age0.40.63.2-0.0-0.70.9-0.21.4-0.7-0.80.3-0.20.71.10.70.80.70.7-0.7-0.10.5-0.11.1-1.8
Bone surface1.01.83.01.7-1.61.6-1.61.61.51.5-1.6-1.5-1.4-1.3-1.3-1.3-1.3-1.31.31.01.00.5-0.80.4
Bone volume1.42.54.92.2-2.01.9-2.11.92.02.1-1.9-1.7-1.7-1.7-1.4-1.4-1.4-1.41.40.90.90.2-0.70.3
Breakpoint value in progressive ratio session2.22.73.8-1.91.3-1.31.4-0.9-1.9-1.71.91.71.91.81.91.91.91.9-1.9-1.6-1.0-1.11.5-1.3
Number of licking bursts1.72.79.3-2.63.1-3.02.6-2.8-2.0-1.91.71.30.10.60.30.30.30.3-0.2-0.5-0.5-0.7-1.01.3
Context. condit. distance diff. score0.70.81.3-0.70.5-0.50.7-0.4-1.0-0.81.00.90.91.21.01.01.01.0-1.0-1.1-0.8-1.20.9-1.1
Locomotion velocity, session 10.30.30.9-0.20.3-0.3-0.1-0.30.40.3-0.4-0.3-0.5-0.7-0.8-0.9-0.8-0.80.80.3-0.5-0.1-0.90.9
Locomotion distance, session 10.30.41.60.8-1.21.1-1.21.30.70.7-0.6-0.40.30.2-0.1-0.1-0.1-0.10.0-0.30.0-0.80.5-0.8
Locomotion velocity, session 20.20.30.8-0.90.7-0.80.2-0.7-0.00.10.10.2-0.1-0.1-0.5-0.5-0.5-0.50.5-0.2-0.4-0.6-0.70.8
Locomotion distance, session 21.21.73.41.3-1.61.5-1.81.61.61.5-1.6-1.4-0.9-0.9-1.4-1.4-1.4-1.41.30.80.70.0-0.80.3
Locomotion velocity, session 30.10.10.40.2-0.60.5-0.70.60.40.2-0.4-0.4-0.0-0.1-0.3-0.4-0.3-0.30.30.20.30.1-0.1-0.1
Locomotion distance, session 30.70.71.70.2-0.20.4-0.30.50.3-0.0-0.7-1.1-0.8-0.9-1.0-1.1-1.0-1.01.01.31.31.2-1.00.6
Stereotopy head waving bouts, day 30.91.02.3-1.00.7-0.80.8-0.7-0.8-0.61.11.21.21.31.01.11.01.0-1.1-1.3-0.8-1.50.9-0.7
Stereotopy head waving duration, day 30.60.71.7-0.60.3-0.40.3-0.3-0.4-0.10.71.00.91.10.91.00.90.9-1.0-1.2-0.7-1.30.9-0.7
Locomotion velocity, session 71.21.32.80.6-0.91.1-1.11.30.70.2-1.2-1.6-1.1-1.1-1.2-1.3-1.2-1.21.11.71.31.4-1.00.4
Locomotion distance, session 70.50.61.6-0.20.2-0.10.00.10.10.1-0.5-0.9-1.0-0.8-1.0-1.0-1.0-1.00.91.10.40.9-1.21.0
Stereotopy head waving bouts, day 70.20.20.80.1-0.30.2-0.30.20.10.10.10.30.60.30.40.30.40.4-0.4-0.60.1-0.90.6-0.6
Stereotopy head waving duration, day 70.70.82.71.4-1.71.6-1.41.60.90.7-0.8-0.70.1-0.2-0.0-0.2-0.0-0.00.10.31.10.20.6-0.8
Locomotion velocity, session 80.10.10.4-0.60.1-0.2-0.1-0.10.10.00.00.20.20.2-0.1-0.1-0.1-0.10.1-0.4-0.5-0.7-0.1-0.0
Locomotion distance, session 80.10.22.10.0-0.40.4-0.50.60.20.3-0.1-0.10.10.4-0.2-0.2-0.2-0.20.1-0.6-0.0-1.50.1-0.7
Degree of sensitization distance0.50.62.8-0.30.3-0.50.2-0.5-0.10.40.50.90.50.60.60.70.60.6-0.7-1.3-1.7-1.40.6-0.3
Degree of sensitization stereotypy0.70.71.81.1-1.31.2-1.31.21.00.8-1.0-0.9-0.4-0.7-0.6-0.8-0.6-0.60.70.60.90.2-0.2-0.1
Conditioned locomotion0.30.31.2-0.91.0-0.71.0-0.5-1.1-1.10.70.20.30.30.40.20.30.3-0.20.30.00.5-0.30.1
Cocaine response after cond. corrected0.10.10.3-0.40.6-0.60.4-0.4-0.3-0.10.20.20.0-0.1-0.0-0.00.00.0-0.00.1-0.20.1-0.30.4
Cocaine response after cond. not corrected0.30.30.90.8-0.30.4-0.30.40.50.5-0.6-0.6-0.7-0.8-0.5-0.5-0.5-0.50.50.80.41.0-0.50.6
Cocaine response before conditioning2.63.05.82.4-1.81.9-1.71.71.81.4-2.0-2.1-1.9-1.9-1.6-1.6-1.5-1.51.61.91.81.9-1.10.8
Saline control response0.20.30.60.20.1-0.20.4-0.4-0.3-0.30.50.70.40.50.70.80.70.7-0.7-0.7-0.4-0.40.8-0.5
Bone: connectivity density0.40.61.81.1-1.31.3-1.11.30.90.9-0.9-0.9-0.5-0.5-0.4-0.3-0.4-0.40.40.50.60.60.1-0.3
Bone: cortical apparent density0.40.62.2-1.21.4-1.41.2-1.5-0.7-0.40.70.7-0.20.00.10.10.10.1-0.1-0.3-0.0-0.2-0.50.8
Bone: cortical area2.74.17.32.6-2.42.3-2.72.32.62.5-2.5-2.2-1.9-1.7-2.0-2.0-2.0-2.02.01.31.30.4-1.10.7
Bone: cortical porosity0.40.41.60.8-1.21.2-0.81.30.30.3-0.3-0.40.20.20.40.40.40.4-0.3-0.00.20.20.8-1.1
Bone: cortical porosity0.50.52.10.3-0.80.8-0.30.9-0.2-0.20.30.20.70.70.90.90.90.9-0.9-0.5-0.2-0.11.3-1.5
Bone: cortical thickness1.42.34.91.6-1.21.0-1.80.92.22.2-1.8-1.3-1.6-1.4-1.8-1.8-1.8-1.81.80.60.2-0.4-1.31.3
Bone: cortical thickness1.21.43.20.9-0.30.1-0.9-0.21.71.8-1.2-0.6-1.4-1.3-1.5-1.5-1.5-1.51.50.3-0.4-0.4-1.41.8
Bone: cortical tissue density0.40.62.2-1.21.4-1.41.2-1.5-0.7-0.50.70.7-0.10.10.20.20.20.2-0.1-0.3-0.0-0.2-0.40.7
Condit. Reinf. active minus inactive responses0.50.51.20.00.0-0.10.4-0.1-0.5-0.20.60.70.80.90.91.00.90.9-1.1-0.8-0.5-0.81.0-1.1
Condit. Reinf. active-inactive response ratio0.40.41.50.4-0.30.40.20.3-0.4-0.20.40.30.50.70.91.00.90.9-1.1-0.50.2-0.11.0-1.2
Condit. Reinf. active responses0.40.51.6-0.20.2-0.30.3-0.2-0.4-0.30.60.70.90.90.70.70.70.7-0.7-1.0-0.7-1.30.7-0.9
Condit. Reinf. inactive responses0.10.10.9-0.40.1-0.2-0.0-0.1-0.1-0.30.20.40.60.50.1-0.00.10.10.1-0.6-0.6-1.00.1-0.2
Incentive salience index mean0.10.10.40.4-0.30.4-0.00.5-0.2-0.1-0.0-0.30.00.20.10.20.10.1-0.30.20.60.30.2-0.6
Condit. Reinf. lever presses0.10.21.5-0.0-0.10.30.10.5-0.5-0.60.0-0.5-0.10.00.0-0.00.00.00.00.61.20.8-0.1-0.4
Condit. Reinf. active minus inactive responses0.81.13.70.6-1.31.2-0.81.10.20.40.10.30.91.01.01.10.90.9-1.2-1.10.8-1.01.7-1.9
Condit. Reinf. active-inactive response ratio0.91.13.40.3-0.60.5-0.10.4-0.3-0.10.60.81.31.21.41.41.31.3-1.5-1.2-0.0-0.71.9-1.7
Condit. Reinf. active responses0.50.72.30.6-1.21.2-0.71.10.20.2-0.1-0.00.50.80.70.70.60.6-0.7-0.61.5-0.51.2-1.5
Condit. Reinf. inactive responses0.91.25.90.8-1.01.1-1.01.10.80.6-1.2-1.4-1.2-0.8-1.0-1.0-1.1-1.11.11.12.40.8-0.80.3
Condit. Reinf. lever presses0.81.13.91.8-2.02.0-1.41.81.00.8-0.9-0.7-0.00.10.20.20.10.1-0.20.01.20.21.0-1.2
Condit. Reinf. lever reinforcers received0.60.82.90.3-0.90.9-0.40.9-0.1-0.10.30.30.81.11.01.10.90.9-1.0-0.91.0-0.71.5-1.7
Conditioned reinforcement - actives0.10.21.10.5-0.1-0.1-0.2-0.20.81.1-0.5-0.1-0.5-0.7-0.3-0.2-0.4-0.40.40.1-0.40.1-0.50.9
Conditioned reinforcement - inactives0.30.41.7-0.71.1-1.20.8-1.3-0.10.00.20.4-0.3-0.3-0.3-0.1-0.3-0.30.3-0.1-0.5-0.2-0.91.2
Conditioned locomotion0.10.10.4-0.50.5-0.50.2-0.3-0.00.10.00.1-0.3-0.4-0.2-0.1-0.2-0.20.20.2-0.10.3-0.40.7
Patch foraging indifference point 0 sec0.40.71.90.7-0.90.7-0.70.90.50.70.00.60.70.60.90.90.70.7-0.8-1.3-0.0-1.21.4-1.1
Patch foraging indifference point AUC0.60.81.70.8-0.90.7-1.00.81.31.2-1.1-0.8-1.0-0.8-1.0-0.9-1.1-1.11.00.50.70.2-0.70.7
Delay disc. indifference point, 0s delay2.93.15.01.0-0.50.5-1.30.61.61.6-1.7-1.7-2.2-2.2-2.1-2.2-2.1-2.12.21.82.21.3-2.12.0
Delay disc. indifference point, 16s delay3.64.06.4-2.22.3-2.52.3-2.4-2.0-1.52.32.51.81.61.81.81.81.8-1.9-2.2-2.0-2.11.0-0.5
Delay disc. indifference point, 2s delay4.44.97.02.4-2.22.1-2.61.92.52.3-2.6-2.5-2.3-2.4-2.2-2.4-2.2-2.22.52.22.01.7-1.61.3
Delay disc. indifference point, 24s delay2.32.65.9-2.22.4-2.42.3-2.4-1.9-1.61.91.91.31.11.31.21.31.3-1.1-1.2-0.5-1.00.30.2
Delay disc. indifference point, 4s delay0.70.71.90.30.2-0.4-0.5-0.30.91.2-0.6-0.2-1.0-1.4-0.9-1.1-0.9-0.91.20.20.3-0.4-1.11.4
Delay disc. indifference point, 8s delay0.40.51.70.50.2-0.2-0.2-0.30.50.6-0.5-0.4-0.9-1.3-0.8-0.8-0.8-0.80.90.50.20.3-1.01.2
Indifference point function ln k0.00.10.20.4-0.40.3-0.50.20.30.5-0.3-0.2-0.1-0.3-0.3-0.4-0.1-0.10.30.1-0.4-0.1-0.10.0
Indifference point function log k0.00.10.20.4-0.40.3-0.50.20.30.5-0.3-0.2-0.1-0.3-0.3-0.4-0.1-0.10.30.1-0.4-0.1-0.10.0
Patch foraging total patch changes 0 sec0.50.92.60.8-1.10.9-0.71.00.60.70.00.60.80.71.01.00.90.9-1.0-1.4-0.2-1.31.6-1.3
Patch foraging total patch changes 12 sec0.20.21.00.1-0.70.6-0.41.00.30.1-0.1-0.10.30.60.30.40.10.1-0.3-0.40.6-0.30.6-0.7
Patch foraging total patch changes 18 sec0.00.00.20.1-0.0-0.1-0.00.10.40.2-0.10.2-0.1-0.20.00.1-0.1-0.1-0.1-0.30.3-0.10.10.3
Patch foraging total patch changes 24 sec0.20.41.31.0-1.10.9-0.80.71.01.1-0.6-0.1-0.20.10.10.3-0.0-0.0-0.1-0.70.3-0.70.6-0.4
Patch foraging total patch changes 6 sec0.91.45.6-0.50.2-0.60.3-0.70.10.40.81.71.11.11.31.31.11.1-1.2-2.3-0.9-2.41.5-0.7
Patch foraging time to switch 0 sec1.02.16.7-2.32.1-1.82.1-1.1-2.4-2.61.81.01.11.21.01.31.01.0-1.1-0.30.30.20.1-0.4
Patch foraging water rate 0 sec0.10.20.90.7-0.90.8-0.71.00.60.7-0.5-0.3-0.3-0.1-0.1-0.4-0.1-0.10.30.10.0-0.30.2-0.3
Patch foraging water rate 12 sec0.40.94.02.0-1.61.3-1.30.91.61.7-1.0-0.3-0.3-0.5-0.1-0.2-0.0-0.00.1-0.2-0.4-0.30.6-0.2
Patch foraging water rate 18 sec0.40.61.90.4-0.90.7-0.60.60.30.60.00.40.80.70.70.40.80.8-0.5-0.8-1.4-1.01.1-1.1
Patch foraging water rate 24 sec0.50.82.40.7-0.70.5-1.10.31.31.6-1.0-0.6-1.1-0.8-1.0-1.2-0.8-0.81.00.4-0.0-0.2-0.70.7
Patch foraging water rate 6 sec0.20.20.70.4-0.0-0.2-0.2-0.80.70.8-0.30.2-0.3-0.3-0.3-0.3-0.2-0.20.4-0.4-0.7-0.8-0.20.7
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.0-0.10.1-0.20.10.20.1-0.1-0.1-0.2-0.2-0.1-0.0-0.1-0.1-0.20.2-0.20.20.10.1
Distance traveled before self-admin0.50.71.40.2-0.10.0-0.4-0.10.90.9-0.8-0.5-1.1-1.1-1.0-1.1-1.0-1.00.90.60.80.2-1.01.2
Distance traveled after self-admin3.44.26.31.6-1.21.2-1.61.12.11.9-2.2-2.2-2.4-2.5-2.4-2.5-2.4-2.42.52.31.21.9-2.12.0
Extensor digitorum longus weight5.220.629.45.1-4.34.5-4.74.14.64.3-5.2-5.4-5.0-4.9-4.6-4.5-4.7-4.74.54.74.64.1-3.32.5
Bone: elastic displacement0.60.71.9-1.30.9-1.00.8-1.1-0.5-0.20.81.20.70.60.70.80.70.7-0.8-1.2-1.4-0.90.50.1
Bone: elastic work0.30.41.10.5-0.60.5-0.80.50.91.1-0.8-0.5-0.8-0.9-0.6-0.5-0.6-0.60.50.20.10.1-0.40.6
Bone: endosteal estimation1.32.96.22.2-2.32.5-2.02.41.51.4-1.9-2.2-1.5-1.4-1.2-1.2-1.2-1.21.21.72.11.6-0.5-0.3
Bone: endosteal perimeter1.02.24.91.5-1.51.7-1.51.91.00.8-1.6-2.0-1.4-1.3-1.4-1.4-1.4-1.41.41.72.21.3-1.00.2
Epididymis fat weight0.51.65.72.3-2.42.3-2.11.71.61.7-1.4-1.0-0.5-0.1-0.4-0.3-0.4-0.40.30.00.2-0.30.6-1.0
Delta time in closed arm before/after self-admin0.90.83.10.2-0.30.6-0.50.80.1-0.2-0.7-1.2-0.9-0.8-0.9-0.7-0.9-0.90.91.51.61.8-0.90.5
Delta time in open arm before/after self-admin1.01.02.71.5-1.61.5-1.51.41.41.5-1.2-0.9-0.6-0.5-0.6-0.6-0.6-0.60.70.10.1-0.40.1-0.4
Diff in mean of infusions in LGA sessions1.11.34.2-0.70.3-0.50.3-0.7-0.5-0.10.91.31.21.21.21.21.21.2-1.1-1.8-1.9-2.01.2-1.0
Delay discount exponential model param0.20.20.70.3-0.70.8-0.30.90.0-0.2-0.1-0.30.30.60.20.30.20.2-0.30.10.10.30.6-0.8
Extinction: sum of active levers before priming0.50.51.2-0.90.7-0.60.8-0.4-1.1-1.10.90.60.80.90.80.80.80.8-0.7-0.40.1-0.10.5-0.6
Active lever presses in extinction session 60.30.30.60.1-0.20.2-0.10.4-0.2-0.20.30.30.70.70.70.60.70.7-0.5-0.5-0.5-0.40.8-0.7
Bone: final force3.96.311.13.0-3.13.0-3.32.93.13.0-3.1-2.8-2.5-2.2-2.4-2.5-2.4-2.42.41.81.70.9-1.30.8
Bone: final moment3.14.99.72.7-2.92.8-3.12.72.92.8-2.8-2.4-2.1-1.8-2.0-2.1-2.0-2.02.01.41.30.6-1.00.5
Food consumed during 24 hour testing period1.62.23.11.7-1.51.4-1.71.41.71.4-1.8-1.7-1.6-1.6-1.6-1.6-1.6-1.61.71.30.70.7-1.10.7
Glucose0.10.20.7-0.70.3-0.40.2-0.3-0.1-0.40.30.50.50.80.10.10.10.1-0.1-0.6-0.9-0.70.2-0.2
Heart weight0.10.10.3-0.0-0.30.2-0.50.30.30.3-0.2-0.10.1-0.0-0.3-0.2-0.3-0.30.3-0.2-0.6-0.5-0.2-0.0
Delay discount hyperbolic model param0.10.20.6-0.1-0.30.40.10.4-0.3-0.50.20.00.50.80.40.50.40.4-0.5-0.1-0.20.10.6-0.8
Intermittent access intake day 1-15 change0.51.03.6-1.01.3-1.30.9-1.3-0.1-0.1-0.1-0.2-1.1-1.0-1.0-1.1-0.8-0.80.81.00.30.9-1.71.9
Intermittent access intake escalation0.51.03.6-1.31.5-1.51.0-1.4-0.2-0.00.10.0-0.9-0.8-0.9-1.0-0.7-0.70.70.80.10.6-1.61.9
Intermittent access intake escalation 21.11.34.4-1.51.6-1.61.0-1.4-0.2-0.00.0-0.1-1.2-1.1-1.2-1.1-0.8-0.80.80.90.30.8-1.92.1
Intermitt. access day 1 inactive lever presses0.10.31.0-0.50.8-0.80.6-0.6-0.1-0.20.1-0.0-0.6-0.5-0.5-0.3-0.4-0.40.40.3-0.10.4-0.81.0
Intermitt. access day 15 inactive lever presses0.20.51.10.7-0.50.5-0.60.50.60.5-0.8-0.9-1.0-0.5-1.0-0.8-0.8-0.80.80.70.30.3-0.80.4
Intermitt. access escalation Index0.10.20.50.6-0.70.7-0.50.60.30.3-0.3-0.30.1-0.30.0-0.10.20.2-0.20.3-0.00.50.3-0.3
Intermittent access day 1 total infusions0.20.41.31.0-1.11.1-1.01.10.60.5-0.5-0.4-0.00.20.10.20.00.0-0.0-0.2-0.4-0.20.6-0.8
Intermittent access day 15 total infusions0.10.10.4-0.20.3-0.30.0-0.30.20.3-0.2-0.1-0.6-0.3-0.4-0.4-0.4-0.40.40.3-0.40.1-0.60.6
Intermittent access terminal intake (last 3 days)0.10.10.30.1-0.20.2-0.40.20.40.5-0.4-0.3-0.5-0.3-0.3-0.3-0.3-0.30.30.2-0.30.0-0.30.3
Intermittent access total infusions0.50.61.51.1-1.11.0-1.21.01.21.2-1.0-0.7-0.7-0.5-0.5-0.5-0.6-0.60.60.4-0.20.2-0.20.1
Intermittent access day 1 locomotion0.20.30.60.7-0.80.7-0.70.70.50.5-0.3-0.00.20.50.20.30.10.1-0.1-0.5-0.5-0.70.6-0.6
Intermittent access day 15 total locomotion0.20.42.10.10.2-0.30.3-0.4-0.00.10.40.70.50.50.60.80.70.7-0.7-0.8-1.5-0.70.5-0.1
Intermittent access total locomotion0.30.41.10.6-0.70.6-0.60.50.40.6-0.10.20.30.70.50.60.40.4-0.4-0.8-1.0-0.80.8-0.8
Intermittent access standard deviation1.63.46.20.5-0.70.7-1.30.81.71.7-1.9-1.9-2.5-2.0-2.3-2.3-2.3-2.32.32.01.41.3-2.31.9
Left kidney weight1.88.316.14.0-3.63.5-3.63.33.63.8-3.5-3.1-3.0-2.7-2.5-2.5-2.4-2.42.52.12.01.2-1.20.8
Right kidney weight1.98.520.24.5-4.14.0-4.03.53.84.0-3.6-3.1-2.6-2.5-2.2-2.2-2.2-2.22.31.81.61.1-0.70.4
Cocaine induced anxiety0.10.10.2-0.50.5-0.40.5-0.4-0.4-0.40.2-0.0-0.10.2-0.1-0.2-0.3-0.30.30.30.40.1-0.40.2
Post-drug Anxiety0.70.72.0-1.20.9-1.00.8-0.9-0.6-0.20.81.10.71.00.70.60.60.6-0.6-1.2-1.1-1.40.3-0.2
Baseline Anxiety0.20.31.4-0.1-0.1-0.2-0.3-0.10.61.0-0.00.50.1-0.10.10.20.20.2-0.2-0.9-1.2-1.10.20.1
Tail length0.41.54.42.0-1.71.4-1.71.32.02.1-1.5-0.9-1.1-1.1-0.9-1.1-0.9-0.90.90.4-0.2-0.2-0.20.4
Length with tail0.10.42.50.8-0.60.4-0.50.40.60.8-0.20.30.20.50.20.10.10.1-0.1-0.9-0.9-1.60.5-0.5
Length without tail0.51.54.4-1.31.3-1.41.3-1.3-1.1-1.01.31.51.31.61.00.80.90.9-0.7-1.5-1.2-2.10.5-0.4
Times rat made contact with spout2.93.45.31.3-0.91.1-1.41.11.51.1-1.9-2.2-2.2-2.0-2.2-2.3-2.2-2.22.32.21.71.6-2.21.6
Lifetime Intake0.70.92.11.4-1.41.3-1.41.31.41.3-1.2-0.9-0.8-0.7-0.6-0.5-0.7-0.70.70.5-0.10.3-0.20.1
Liver weight, left0.91.53.10.3-0.00.20.80.5-1.2-1.51.10.81.51.21.71.71.61.6-1.7-0.5-0.40.51.8-1.7
Liver weight, right0.40.81.80.2-0.10.30.50.4-1.0-1.20.70.31.00.81.21.21.21.2-1.20.00.40.81.2-1.3
Locomotor activity0.10.20.80.7-0.50.50.00.1-0.1-0.20.10.10.40.40.70.40.60.6-0.5-0.20.90.00.8-0.8
Locomotor testing distance0.10.20.50.7-0.70.7-0.40.40.30.2-0.2-0.10.00.10.30.10.20.2-0.2-0.10.4-0.10.5-0.6
Locomotor testing rearing0.40.82.40.0-0.20.30.3-0.2-0.6-0.70.70.71.11.21.21.11.21.2-1.1-0.90.1-0.71.4-1.5
Locomotion in novel chamber0.60.72.30.7-1.11.0-0.80.80.20.20.10.31.00.81.00.91.01.0-0.9-0.7-0.2-0.31.5-1.4
Locomotion in novel chamber post-restriction1.21.94.2-0.70.2-0.30.6-0.5-0.8-0.61.21.51.62.01.61.41.61.6-1.6-1.9-1.2-2.11.8-1.7
Fecal boli incidents, locomotor time 10.71.13.1-1.00.5-0.31.0-0.4-1.5-1.81.20.71.31.21.21.01.11.1-1.2-0.20.10.21.1-1.3
Change in fecal boli incidents, locomotor task0.60.62.20.6-0.70.4-1.10.11.01.5-0.30.50.10.10.20.30.40.40.1-1.3-1.1-1.50.5-0.2
Time >=10cm from walls, locomotor time 10.40.41.00.1-0.40.3-0.60.60.60.6-0.7-0.7-0.8-0.4-0.9-1.0-0.7-0.70.70.50.1-0.1-0.80.5
Bouts of movement, locomotor time 12.52.85.0-2.02.0-1.92.2-1.3-2.2-2.22.11.81.61.41.71.81.71.7-1.8-1.3-0.9-0.41.0-0.6
Total resting periods, locomotor time 12.83.25.8-2.12.1-2.02.3-1.5-2.4-2.42.31.91.71.41.91.91.91.9-1.9-1.2-0.7-0.31.1-0.6
Rest time, locomotor task time 10.60.82.5-1.61.6-1.51.3-1.0-1.2-1.31.00.70.30.60.30.30.30.3-0.2-0.20.50.0-0.50.6
Distance moved, locomotor task time 10.60.92.91.7-1.71.5-1.41.21.31.4-1.0-0.7-0.3-0.4-0.3-0.2-0.3-0.30.20.00.1-0.00.5-0.6
Vertical activity count, locomotor time 11.22.85.91.7-1.61.4-2.01.22.32.4-2.1-1.7-1.9-2.0-1.9-1.7-1.8-1.81.71.10.10.7-1.21.2
Time >=10cm from walls, locomotor time 21.32.03.01.4-1.21.2-1.31.31.61.5-1.7-1.6-1.6-1.4-1.7-1.7-1.5-1.51.31.30.70.7-1.30.9
Bouts of movement, locomotor time 20.40.74.5-0.0-0.71.1-0.41.2-0.6-1.10.0-0.70.30.40.30.30.10.1-0.20.82.11.30.7-1.3
Total resting periods, locomotor time 20.40.85.30.2-0.91.2-0.61.3-0.4-0.9-0.2-0.90.10.30.10.1-0.1-0.1-0.10.92.31.40.6-1.1
Rest time, locomotor task time 20.10.10.7-0.40.1-0.20.0-0.1-0.00.20.20.30.10.30.10.1-0.0-0.0-0.1-0.50.2-0.90.1-0.1
Distance moved, locomotor task time 21.82.13.91.1-0.40.4-0.70.41.31.2-1.5-1.5-1.9-2.0-1.9-1.6-1.7-1.71.51.51.51.3-1.71.8
Vertical activity count, locomotor time 21.31.73.50.6-0.20.0-0.70.11.51.6-1.4-1.1-1.8-1.7-1.9-1.5-1.8-1.81.40.80.40.3-1.81.9
Light reinforcement 10.81.95.0-1.60.3-0.40.60.1-1.1-1.31.21.31.92.21.71.71.41.4-1.5-1.5-1.1-1.01.6-1.6
Light reinforcement 20.50.81.7-0.4-0.20.10.20.3-0.5-0.30.70.81.01.21.21.21.11.1-1.1-1.1-1.3-0.71.3-1.2
Bone: marrow area1.22.65.52.1-2.22.3-1.92.31.41.3-1.8-2.1-1.4-1.3-1.1-1.2-1.1-1.11.11.72.11.5-0.4-0.2
Bone: maximum diameter1.83.36.42.4-2.52.5-2.52.52.01.8-2.2-2.2-1.5-1.3-1.5-1.5-1.5-1.51.51.41.60.9-0.60.0
Bone: maximum force3.46.110.02.9-2.92.8-3.22.73.02.9-3.0-2.7-2.5-2.3-2.4-2.5-2.4-2.42.41.81.80.9-1.40.9
Bone: maximum moment2.64.68.42.7-2.72.6-2.92.52.72.7-2.7-2.3-2.1-2.0-2.0-2.0-2.0-2.01.91.41.30.6-1.00.6
Mean time between licks in bursts0.10.31.4-1.00.5-0.40.6-0.1-0.9-1.20.60.30.60.60.50.60.50.5-0.5-0.10.20.20.3-0.5
Mean num. licks in bursts3.35.110.73.2-3.33.2-3.23.12.82.5-2.8-2.5-1.6-1.9-1.7-1.7-1.7-1.71.71.81.21.6-0.50.1
Cd content in liver4.34.89.3-1.30.3-0.61.0-0.7-1.4-1.42.02.42.92.72.82.82.82.8-2.8-2.6-2.0-1.83.1-2.5
Co content in liver0.50.51.70.00.3-0.6-0.1-0.90.91.3-0.30.3-0.6-0.6-0.6-0.5-0.6-0.60.5-0.6-1.3-1.0-0.71.2
Cu content in liver0.50.62.11.3-1.21.1-1.10.71.31.4-0.9-0.5-0.7-0.4-0.3-0.2-0.3-0.30.20.00.50.00.20.0
Fe content in liver0.20.21.0-0.20.5-0.70.4-1.00.10.50.30.6-0.2-0.10.20.20.20.2-0.2-0.6-0.3-0.6-0.00.6
K content in liver0.10.10.40.3-0.60.6-0.50.60.30.2-0.2-0.2-0.10.00.00.10.00.0-0.0-0.00.10.10.3-0.5
Mg content in liver0.20.20.80.1-0.50.6-0.20.7-0.2-0.20.0-0.20.10.30.30.40.30.3-0.40.00.90.30.5-0.8
Mn content in liver0.60.61.51.1-0.80.9-0.80.90.60.5-0.8-1.0-0.9-0.9-0.6-0.5-0.6-0.60.61.01.01.2-0.40.2
Na content in liver3.53.87.41.7-2.12.3-2.22.71.60.9-2.2-2.7-1.8-1.5-2.0-2.0-2.0-2.02.02.41.42.1-1.30.4
Rb content in liver4.04.610.3-1.30.9-1.41.3-1.7-1.0-0.72.12.92.42.32.52.62.52.5-2.5-3.2-1.8-2.92.6-1.6
Se content in liver0.40.50.90.6-0.20.3-0.40.40.50.4-0.7-0.8-0.9-1.0-0.8-0.8-0.8-0.80.80.90.60.8-0.90.8
Sr content in liver0.80.72.31.0-1.01.1-0.90.90.60.2-0.9-1.1-0.7-0.7-0.6-0.6-0.6-0.60.61.20.81.5-0.20.0
Zn content in liver1.01.14.71.4-1.92.0-1.42.20.80.8-1.0-1.1-0.1-0.0-0.2-0.0-0.2-0.20.00.51.10.70.6-1.2
Bone: minimum diameter1.62.95.51.9-2.22.3-2.22.31.71.6-2.0-2.2-1.5-1.3-1.5-1.5-1.5-1.51.51.52.01.0-0.80.1
Time in familiar zone, hab. session 10.30.31.5-0.20.7-0.90.5-1.20.00.00.40.80.10.10.20.20.20.2-0.0-0.7-1.2-0.70.10.5
Time in novel zone, hab. session 10.30.31.70.1-0.80.9-0.61.3-0.1-0.1-0.3-0.70.20.20.0-0.10.00.0-0.10.50.90.50.1-0.7
Total zone transitions, hab. session 11.52.14.81.7-1.91.7-2.21.62.12.1-1.8-1.2-1.0-1.1-1.4-1.5-1.4-1.41.40.40.3-0.8-0.60.2
Total locomotion distance, hab. session 13.04.311.03.0-3.12.8-3.32.72.93.2-2.5-1.8-1.4-1.6-1.6-1.5-1.6-1.61.40.30.8-0.9-0.2-0.3
Locomotion velocity, hab. session 12.23.18.82.5-2.92.6-3.02.52.52.7-2.0-1.4-0.9-1.1-1.1-1.0-1.1-1.10.90.00.7-1.00.2-0.7
Time in familiar zone, hab. session 20.30.30.60.6-0.60.6-0.70.50.80.6-0.7-0.5-0.4-0.4-0.6-0.5-0.6-0.60.70.40.10.4-0.30.3
Time in novel zone, hab. session 20.20.20.4-0.00.1-0.00.3-0.1-0.4-0.30.40.40.50.40.60.50.60.6-0.7-0.3-0.3-0.20.6-0.5
Total zone transitions, hab. session 21.11.43.61.6-1.91.7-1.91.51.71.7-1.4-0.9-0.5-0.4-0.8-1.0-0.8-0.80.90.00.2-1.00.0-0.4
Total locomotion distance, hab. session 21.92.45.81.9-2.21.9-2.41.72.32.3-1.9-1.3-1.1-1.2-1.4-1.4-1.4-1.41.40.30.2-0.9-0.50.1
Locomotion velocity, hab. session 22.12.96.82.1-2.42.2-2.62.02.42.4-2.1-1.6-1.3-1.2-1.6-1.6-1.6-1.61.50.50.4-0.8-0.5-0.0
Novel to familiar place preference ratio0.40.41.3-0.61.0-1.10.8-1.1-0.5-0.10.60.70.10.10.10.10.10.1-0.2-0.7-0.8-1.1-0.30.4
Novelty place preference0.40.51.6-0.81.2-1.30.9-1.2-0.4-0.10.50.6-0.0-0.1-0.2-0.1-0.2-0.20.0-0.6-0.8-1.1-0.60.7
Time in novel zone, NPP test0.40.51.7-0.71.0-1.10.8-1.1-0.4-0.10.60.80.20.20.10.20.10.1-0.2-0.9-1.0-1.3-0.20.4
Total zone transitions, NPP test0.91.33.01.4-1.51.4-1.71.41.61.5-1.4-1.1-0.8-0.8-1.0-1.1-1.0-1.01.00.50.4-0.1-0.40.1
Total locomotion distance, NPP test1.41.94.21.5-1.51.3-1.91.21.92.0-1.7-1.2-1.3-1.4-1.5-1.4-1.5-1.51.40.50.7-0.3-0.90.6
Locomotion velocity, NPP test1.21.73.61.4-1.31.1-1.81.11.81.9-1.6-1.2-1.3-1.4-1.5-1.4-1.5-1.51.40.60.6-0.2-0.90.7
Intraocular pressure0.10.20.80.6-0.70.7-0.40.90.30.6-0.4-0.5-0.3-0.2-0.2-0.0-0.0-0.00.00.30.50.30.0-0.2
Delta distance traveled before/after self-admin0.50.51.21.1-0.91.0-0.91.10.60.5-0.8-0.9-0.4-0.5-0.5-0.6-0.5-0.50.80.90.20.9-0.30.0
Delta ambulatory time before/after self-admin1.11.32.01.4-1.11.2-1.21.21.10.9-1.3-1.4-1.0-1.1-1.1-1.1-1.1-1.11.31.40.41.4-0.80.5
Parametrial fat weight1.12.69.02.9-3.02.7-2.52.22.12.2-1.3-0.50.10.30.40.30.30.3-0.2-0.7-1.0-0.91.8-1.7
Pavlov. Cond. lever latency0.70.83.5-0.30.8-1.30.3-1.70.71.10.11.1-0.2-0.2-0.3-0.3-0.3-0.30.3-1.4-1.3-1.9-0.41.2
Pavlov. Cond. magazine entry latency2.02.59.91.8-2.42.8-1.73.20.5-0.1-1.3-2.1-0.4-0.2-0.3-0.1-0.3-0.30.11.91.72.50.5-1.6
Pavlov. Cond. change in total contacts1.51.67.00.7-0.91.4-0.61.8-0.2-0.8-0.8-1.9-0.8-0.7-0.7-0.7-0.7-0.70.72.32.22.6-0.6-0.4
Pavlov. Cond. index score1.21.56.31.0-1.52.0-0.82.3-0.3-0.9-0.6-1.5-0.10.10.20.20.20.2-0.21.81.82.50.6-1.5
Pavlov. Cond. latency score1.11.35.01.0-1.51.9-0.82.2-0.2-0.7-0.6-1.4-0.10.10.20.20.20.2-0.21.61.72.20.6-1.4
Pavlov. Cond. lever contacts1.21.45.71.0-1.52.0-0.92.4-0.2-0.6-0.7-1.6-0.1-0.1-0.0-0.0-0.0-0.00.01.71.72.20.4-1.3
Pavlov. Cond. magazine entry number1.21.66.2-1.11.5-1.91.0-2.3-0.00.60.91.80.50.20.30.20.30.3-0.2-1.9-1.9-2.5-0.11.0
Pavlov. Cond. intertrial magazine entries1.41.75.8-0.91.1-1.41.0-1.5-0.5-0.11.21.81.21.01.11.01.11.1-0.9-2.1-2.1-2.40.9-0.2
Pavlov. Cond. lever-magazine prob. diff.1.51.87.01.2-1.72.2-1.02.6-0.2-0.8-0.7-1.7-0.20.00.10.10.10.1-0.11.91.82.60.6-1.6
Pavlov. Cond. response bias1.41.77.50.9-1.52.0-0.92.4-0.2-0.8-0.9-1.9-0.5-0.3-0.4-0.3-0.4-0.40.32.22.02.7-0.0-1.1
Pavlov. Cond. lever latency0.60.83.4-1.81.7-1.71.3-1.6-1.0-0.80.80.7-0.1-0.20.10.1-0.0-0.0-0.1-0.1-0.10.1-0.70.9
Pavlov. Cond. magazine entry latency0.40.51.8-0.70.9-0.71.1-0.5-1.2-1.30.80.40.50.40.50.60.60.6-0.60.20.60.70.1-0.0
Pavlov. Cond. change in total contacts0.81.33.70.5-0.50.3-0.10.2-0.10.20.61.11.31.41.21.31.31.3-1.2-1.8-1.0-1.91.7-1.6
Pavlov. Cond. index score0.20.20.70.6-0.40.5-0.00.5-0.2-0.30.20.20.60.60.50.60.70.7-0.5-0.30.2-0.10.8-0.8
Pavlov. Cond. latency score0.10.10.40.6-0.40.5-0.10.5-0.1-0.30.0-0.10.30.30.30.30.40.4-0.30.00.30.20.5-0.5
Pavlov. Cond. lever contacts0.60.83.31.8-1.71.7-1.21.70.80.6-0.7-0.60.20.30.00.00.10.10.00.10.3-0.10.7-1.0
Pavlov. Cond. magazine entry number1.21.52.91.2-1.41.3-1.71.21.61.5-1.5-1.3-1.2-1.2-1.2-1.3-1.3-1.31.30.90.20.4-0.70.5
Pavlov. Cond. intertrial magazine entries1.31.95.41.8-2.32.3-2.02.21.51.3-1.6-1.6-0.8-0.6-0.6-0.7-0.8-0.80.71.01.41.00.2-0.7
Pavlov. Cond. lever-magazine prob. diff.0.20.30.60.4-0.20.30.20.3-0.4-0.50.30.20.70.60.60.70.70.7-0.6-0.20.40.00.7-0.8
Pavlov. Cond. response bias0.30.41.20.9-0.80.8-0.30.8-0.0-0.10.10.10.70.70.50.70.70.7-0.6-0.40.3-0.21.0-1.1
Time in closed arm before self-admin0.00.00.10.3-0.20.2-0.20.10.30.2-0.2-0.1-0.1-0.1-0.2-0.2-0.2-0.20.1-0.0-0.2-0.3-0.1-0.0
Time in closed arm after self-admin0.10.10.4-0.40.6-0.70.3-0.7-0.10.00.30.50.10.00.10.20.10.1-0.1-0.3-0.3-0.2-0.10.5
Time in open arm before self-admin0.70.81.7-1.31.2-1.21.3-1.0-1.2-1.21.10.80.70.80.70.70.70.7-0.9-0.3-0.60.20.3-0.0
Time in open arm after self-admin2.32.54.01.5-1.51.6-1.51.51.51.2-1.8-2.0-1.8-1.5-1.7-1.8-1.7-1.71.71.91.31.5-1.30.7
Bone: periosteal estimation2.96.09.83.1-3.13.1-3.13.12.72.5-2.9-3.0-2.3-2.1-2.2-2.2-2.2-2.22.22.12.41.4-1.20.4
Bone: periosteal perimeter1.22.06.01.8-2.22.2-2.02.41.41.2-1.6-1.8-1.0-0.7-0.9-1.0-0.9-0.90.91.01.50.6-0.2-0.5
Bone: post-yield work1.42.07.32.5-2.72.7-2.12.41.41.2-1.3-1.1-0.1-0.30.1-0.00.10.10.00.40.50.61.2-1.7
Progressive ratio test 1 active lever presses0.20.20.70.7-0.80.8-0.60.90.2-0.0-0.3-0.5-0.2-0.1-0.00.1-0.1-0.10.10.20.40.30.4-0.5
Progressive ratio test 1 breakpoint0.10.20.60.6-0.70.8-0.50.80.1-0.1-0.3-0.4-0.2-0.10.00.1-0.1-0.10.10.20.40.30.4-0.5
Progressive ratio test 1 inactive lever presses0.00.10.40.4-0.20.3-0.10.5-0.2-0.6-0.0-0.20.00.10.00.1-0.1-0.10.10.20.10.40.2-0.3
Progressive ratio test 2 active lever presses0.10.20.50.3-0.20.2-0.00.1-0.3-0.60.30.20.40.30.50.60.40.4-0.4-0.3-0.4-0.00.7-0.6
Progressive ratio test 2 breakpoint0.20.20.60.3-0.10.20.00.1-0.4-0.60.40.30.50.50.60.70.50.5-0.5-0.4-0.5-0.20.8-0.7
Progressive ratio test 2 inactive lever presses0.10.20.90.9-0.70.8-0.60.60.40.2-0.4-0.4-0.3-0.1-0.20.0-0.1-0.10.10.2-0.20.20.2-0.3
Incentive Sensitization - Responses0.10.10.50.20.10.00.2-0.2-0.4-0.70.30.10.30.10.30.30.30.3-0.30.0-0.20.30.4-0.3
Incentive Sensitization - Breakpoint0.10.10.40.3-0.00.10.1-0.1-0.4-0.60.30.20.40.20.40.40.40.4-0.4-0.1-0.30.20.5-0.4
Sum of active levers in priming session hrs 5-63.33.05.5-1.20.5-0.41.0-0.2-2.0-2.01.81.42.22.22.22.22.22.2-2.3-1.5-0.8-0.92.1-2.3
Progressive ratio0.30.41.50.3-0.30.2-0.30.30.10.40.30.60.60.40.70.80.80.8-0.4-1.1-1.2-0.91.0-0.8
Food seeking constrained by brief footshock0.50.61.5-1.01.1-1.21.0-0.9-0.8-0.60.91.00.70.50.60.50.60.6-0.5-0.7-1.0-0.60.20.1
Seeking ratio, punishment vs. effort0.30.41.6-0.10.10.10.10.2-0.1-0.3-0.4-0.8-0.5-0.4-0.7-0.9-0.7-0.70.41.31.21.2-0.80.5
Retroperitoneal fat weight1.25.214.42.7-3.33.0-2.22.11.21.6-0.30.51.82.22.01.91.91.9-1.9-2.3-1.9-2.43.6-3.8
Reaction time number correct0.71.42.3-1.00.8-0.71.1-0.4-1.3-1.51.31.21.51.51.51.11.41.4-1.2-0.9-1.4-0.71.1-1.1
Reaction time mean minus median0.10.21.00.6-0.40.4-0.3-0.20.60.6-0.5-0.4-0.5-0.3-0.5-0.2-0.4-0.40.30.41.00.5-0.30.4
Reaction time mean minus median AUC0.10.30.70.10.0-0.10.3-0.8-0.10.10.40.60.60.60.70.80.70.7-0.8-0.6-0.0-0.20.8-0.4
Reaction time num false alarms0.50.71.9-0.71.2-1.20.9-1.1-0.30.20.10.0-1.0-0.8-0.7-0.8-0.7-0.70.70.4-0.20.0-1.31.4
Reaction time num false alarms AUC0.20.30.9-0.70.9-0.90.8-0.7-0.4-0.10.2-0.0-0.6-0.5-0.4-0.5-0.4-0.40.30.4-0.20.1-0.90.8
Reaction time trials correct on left0.71.42.3-1.00.8-0.71.1-0.4-1.3-1.51.31.21.51.51.51.11.41.4-1.2-0.9-1.4-0.71.1-1.1
Reaction time trials on left0.81.52.5-1.00.7-0.71.1-0.4-1.3-1.51.31.21.61.51.51.21.51.5-1.3-0.9-1.4-0.71.2-1.2
Reaction time mean0.10.20.90.9-0.70.7-0.50.20.60.8-0.5-0.4-0.3-0.2-0.30.2-0.1-0.1-0.10.20.50.50.2-0.2
Reaction time mean AUC0.10.10.30.5-0.40.5-0.20.00.10.3-0.1-0.20.00.10.00.50.20.2-0.40.10.30.50.4-0.4
Median of all reaction times0.20.21.01.0-0.80.8-0.50.40.50.7-0.4-0.4-0.1-0.1-0.10.30.10.1-0.20.20.30.50.4-0.4
Reaction time omissions0.60.92.2-0.2-0.00.20.60.1-1.0-1.00.80.61.51.51.11.21.31.3-1.2-0.4-0.3-0.01.3-1.5
Reaction time false alarm rate0.71.02.7-0.20.6-0.50.2-0.40.30.7-0.6-0.7-1.5-1.4-1.3-1.2-1.2-1.21.21.00.70.6-1.61.6
Reaction time premature initiation rate2.02.75.21.2-1.11.2-1.31.01.51.3-1.8-1.9-1.9-1.8-1.9-1.8-1.9-1.91.81.92.31.7-1.61.2
Reaction time premature initiations0.40.71.70.3-0.50.6-0.50.60.60.3-0.9-1.1-0.9-0.8-0.9-1.0-1.0-1.01.01.21.31.2-0.90.5
Std. dev. reaction times0.10.20.60.8-0.70.6-0.5-0.00.60.8-0.4-0.2-0.10.1-0.20.1-0.0-0.0-0.0-0.10.60.00.3-0.2
Reaction time trials completed0.81.52.5-1.00.7-0.71.1-0.4-1.3-1.51.31.21.61.51.51.21.51.5-1.3-0.9-1.4-0.71.2-1.2
Reaction time trials AUC0.61.11.9-0.80.5-0.50.9-0.3-1.1-1.21.11.01.41.31.31.01.31.3-1.1-0.8-1.3-0.61.1-1.1
Run reversals in cocaine runway, females7.67.611.42.8-2.12.1-2.61.92.92.7-3.1-3.0-3.1-3.4-3.1-3.0-3.0-3.03.13.02.52.5-2.52.2
Run reversals in cocaine runway, males0.30.31.8-0.81.0-1.00.8-1.3-0.5-0.50.50.50.1-0.10.0-0.00.00.0-0.0-0.1-0.4-0.1-0.40.7
Latency to leave start box in cocaine runway0.91.02.7-0.2-0.0-0.20.20.0-0.20.10.71.11.21.41.10.81.11.1-1.3-1.4-1.5-1.71.2-1.0
Latency to leave start box in cocaine runway, F0.70.81.9-0.40.1-0.10.40.4-0.7-0.60.80.81.21.41.10.61.21.2-1.4-0.7-0.6-0.81.1-1.1
Latency to leave start box in cocaine runway, M0.60.63.30.1-0.1-0.2-0.1-0.60.30.70.30.90.50.40.50.60.50.5-0.5-1.3-1.8-1.40.8-0.3
Std. dev. time between licks in bursts0.20.31.1-0.3-0.50.7-0.21.0-0.4-0.70.1-0.30.50.70.50.60.50.5-0.50.20.00.60.6-1.0
Total sessions with >9 infusions2.93.59.02.9-3.02.9-2.82.72.42.1-2.3-2.0-1.1-1.4-1.0-0.9-1.1-1.11.11.20.81.10.1-0.3
Short access day 1 total inactive lever presses0.20.30.50.7-0.70.7-0.70.60.70.5-0.7-0.7-0.5-0.3-0.5-0.4-0.7-0.70.70.40.50.2-0.30.1
Short access day 10 total inactive lever presses0.30.83.0-1.61.7-1.61.4-1.2-1.2-1.31.00.70.10.40.00.20.20.2-0.2-0.2-0.4-0.2-0.60.7
Short access day 1 total infusions1.01.43.92.0-1.51.5-1.41.41.51.3-1.5-1.2-1.0-1.2-0.9-0.9-0.9-0.90.91.00.50.9-0.40.4
Short access day 10 total infusions1.31.74.22.0-2.02.0-1.82.01.51.1-1.5-1.5-0.9-1.2-0.8-0.7-0.9-0.90.91.10.61.2-0.1-0.1
Short access total infusions1.92.45.82.4-2.42.3-2.32.22.01.9-1.9-1.6-1.1-1.3-1.0-0.9-1.0-1.01.01.00.51.0-0.10.0
Short access day 1 locomotion0.70.81.51.2-0.70.6-0.70.51.21.2-1.1-0.9-1.1-1.1-0.9-0.9-1.0-1.01.00.80.50.8-0.81.0
Short access day 10 total locomotion1.62.95.51.7-2.32.3-2.32.31.71.3-2.0-2.1-1.4-1.2-1.4-1.3-1.7-1.71.71.61.61.5-0.50.0
Short access total locomotion1.72.06.02.1-2.52.3-2.32.22.12.1-1.7-1.3-0.7-0.6-0.6-0.5-0.8-0.80.80.40.30.20.3-0.5
One hour access (0.3 mA shock)0.30.30.90.3-0.30.4-0.20.4-0.3-0.30.30.30.50.40.80.80.70.7-0.7-0.4-0.4-0.10.9-0.9
Compulsive drug intake0.60.72.00.1-0.30.4-0.00.3-0.6-0.60.60.61.31.01.21.10.90.9-0.9-0.7-0.4-0.31.4-1.4
One hour access (shock baseline)0.00.10.5-0.20.3-0.40.2-0.4-0.00.10.10.2-0.2-0.00.00.10.20.2-0.2-0.2-0.7-0.3-0.10.3
Social response proportion0.91.12.60.2-0.20.20.30.2-0.5-0.60.80.91.41.11.41.51.41.4-1.4-1.0-1.2-0.51.6-1.4
Social responses1.41.83.1-0.90.6-0.51.0-0.0-1.4-1.51.41.21.81.81.61.51.61.6-1.6-1.2-0.4-1.01.5-1.6
Social time1.21.64.1-1.11.0-1.11.2-0.9-1.1-1.11.41.51.31.41.31.41.31.3-1.4-1.5-2.0-1.31.1-0.8
Soleus weight2.36.816.53.7-3.02.8-3.22.33.54.1-3.2-2.5-2.8-2.9-2.4-2.3-2.3-2.32.31.51.30.9-1.41.4
Bone: stiffness3.35.37.72.7-2.12.0-2.61.92.82.7-2.8-2.5-2.5-2.2-2.6-2.7-2.6-2.62.61.81.50.6-1.91.5
Tibialis anterior weight5.618.931.05.5-5.15.0-5.64.65.45.2-5.4-4.8-4.2-4.1-4.1-4.1-4.2-4.24.23.42.82.3-2.41.7
Time to tail flick, vehicle, before self-admin0.20.20.60.4-0.40.4-0.50.30.60.6-0.6-0.5-0.6-0.6-0.6-0.4-0.6-0.60.50.20.80.0-0.40.3
Time to tail flick, vehicle, after self-admin3.04.06.1-2.41.9-1.82.1-1.8-2.5-2.42.42.12.12.32.02.02.02.0-1.9-1.9-1.2-1.81.4-1.5
Time to tail flick, test, before self-admin0.40.50.90.4-0.00.1-0.1-0.10.30.1-0.5-0.7-0.8-0.8-0.9-0.8-0.9-0.90.81.00.70.8-0.90.7
Time to tail flick, test, after self-admin0.80.82.9-0.20.6-0.20.5-0.1-0.5-1.0-0.2-0.9-0.9-0.9-0.9-0.7-0.9-0.90.91.51.31.7-1.20.9
Delta time to tail flick, vehicle, before/after SA1.31.22.3-0.80.4-0.40.6-0.4-1.1-1.01.11.11.41.51.41.21.41.4-1.2-1.2-1.2-1.11.2-1.3
Delta time to tail flick, test, before/after SA0.20.20.60.3-0.30.4-0.20.50.1-0.1-0.3-0.6-0.4-0.5-0.3-0.3-0.3-0.30.30.60.60.8-0.20.1
Tibia length0.00.10.50.6-0.30.1-0.3-0.10.60.7-0.30.1-0.2-0.2-0.1-0.0-0.1-0.10.0-0.4-0.6-0.60.10.2
Ambulatory time before self-admin0.40.62.1-0.20.4-0.60.0-0.70.70.9-0.5-0.1-1.0-1.0-0.9-1.0-0.9-0.90.90.20.4-0.3-1.11.5
Ambulatory time after self-admin3.74.36.71.5-1.11.1-1.61.02.22.1-2.3-2.1-2.5-2.6-2.5-2.6-2.5-2.52.62.21.21.7-2.32.2
Bone: tissue strength0.40.41.20.4-0.10.1-0.30.10.50.6-0.6-0.6-1.1-1.1-0.8-0.7-0.8-0.80.70.50.60.3-0.90.9
Total heroin consumption1.92.33.9-1.00.4-0.30.9-0.2-1.5-1.51.51.31.91.91.91.91.91.9-2.0-1.6-1.0-1.21.9-2.0
Bone: trabecular number0.61.02.21.1-1.11.0-1.30.91.31.5-1.2-1.0-1.1-1.1-1.0-1.0-1.0-1.01.10.40.4-0.2-0.60.4
Bone: trabecular spacing1.01.33.4-0.90.8-0.51.3-0.3-1.7-1.81.30.81.21.01.51.41.51.5-1.5-0.30.30.51.1-1.0
Bone: trabecular thickness1.31.66.61.9-1.91.5-2.01.12.12.6-1.3-0.3-0.5-0.5-0.5-0.4-0.5-0.50.5-0.9-1.2-1.60.5-0.4
Bone: trabecular tissue density0.10.10.70.00.2-0.3-0.1-0.30.20.4-0.10.0-0.2-0.2-0.4-0.4-0.4-0.40.4-0.2-0.2-0.8-0.50.4
Water consumed over 24 hours1.31.75.0-0.31.1-0.90.7-0.9-0.1-0.4-0.4-0.9-1.5-1.5-1.4-1.5-1.4-1.41.51.61.61.4-2.22.0
Number of responses in last shaping day0.30.30.50.7-0.40.5-0.40.50.40.2-0.6-0.6-0.6-0.7-0.5-0.6-0.6-0.60.60.60.50.5-0.40.3