Hub : Genes

Syt17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio XM_006230104.2 0.04 0.03 1.4e-04 0.03 0.02 0.02 0.02 3.7e-04 3.0e-03 2.9e-03 5.2e-03
2 Liver gene expression Syt17 0.05 0.03 3.8e-05 0.01 0.02 0.01 0.01 1.6e-02 2.6e-03 5.2e-02 1.0e-02
3 PL intron excision ratio chr1_172757188_172757416 0.04 0.02 3.3e-04 0.02 0.03 0.02 0.02 6.3e-03 7.6e-04 2.9e-03 2.4e-03
4 BLA isoform ratio XM_006230104.2 0.06 0.04 2.9e-03 0 0.02 0 0.01 1.6e-01 1.8e-02 1.6e-01 1.1e-01
5 BLA alternative TSS XM_006230104.2 0.08 0.05 5.5e-04 0.03 0.03 0.03 0.04 1.4e-02 6.0e-03 7.9e-03 2.7e-03
6 BLA alternative TSS XM_006230104.2 0.08 0.05 5.1e-04 0.03 0.03 0.03 0.04 1.2e-02 6.7e-03 8.4e-03 2.4e-03
7 BLA alternative TSS NM_138849.2 0.07 0.05 9.5e-04 0.02 0.03 0.02 0.04 2.2e-02 8.5e-03 1.8e-02 4.4e-03
8 BLA alternative TSS NM_138849.2 0.07 0.05 9.9e-04 0.02 0.03 0.03 0.04 2.0e-02 1.2e-02 1.5e-02 4.8e-03
9 Brain isoform ratio XM_006230104.2 0.04 0.03 1.8e-03 0.03 0.02 0.02 0.02 7.9e-04 7.7e-03 7.5e-03 3.1e-03
10 pVTA gene expression Syt17 0.15 0.08 2.3e-05 0.13 0.11 0.1 0.11 4.3e-06 1.9e-05 2.8e-05 2.6e-05
11 NAcc intron excision ratio chr1_172757193_172761477 0.02 0.01 8.2e-03 0.01 0.01 0 0 3.6e-02 3.9e-02 2.3e-01 7.5e-02
12 OFC mRNA stability Syt17 0.84 0.09 2.2e-15 0.37 0.35 0.27 0.29 8.7e-10 4.5e-09 3.3e-07 1.2e-07
13 Adipose mRNA stability Syt17 0.05 0.03 2.6e-04 0.03 0.02 0.02 0.02 1.9e-04 2.9e-03 2.6e-03 9.9e-04
14 NAcc gene expression Syt17 0.09 0.05 2.1e-08 0.08 0.06 0.06 0.08 1.3e-09 6.2e-08 9.3e-08 1.8e-09
15 LHb gene expression Syt17 0.2 0.11 3.5e-03 0.07 0.06 0.05 0.04 1.1e-02 1.2e-02 2.1e-02 3.8e-02
16 Brain gene expression Syt17 0.23 0.11 2.6e-13 0.09 0.12 0.14 0.13 1.5e-08 1.5e-11 1.6e-12 5.0e-12
17 PL mRNA stability Syt17 0.09 0.05 1.8e-08 0.05 0.06 0.05 0.04 8.5e-06 8.0e-07 1.9e-06 1.1e-05
18 Brain alternative TSS XM_006230104.2 0.06 0.04 3.5e-04 0.02 0.03 0.02 0.02 3.0e-03 8.8e-04 3.7e-03 3.7e-03
19 Brain alternative TSS XM_006230104.2 0.06 0.04 3.3e-04 0.02 0.03 0.02 0.02 3.0e-03 8.1e-04 3.4e-03 3.5e-03
20 BLA gene expression Syt17 0.09 0.06 2.8e-03 0 0.01 0.01 0 3.3e-01 6.8e-02 1.3e-01 2.7e-01
21 Brain isoform ratio NM_138849.2 0.04 0.03 6.6e-03 0 0.02 0.01 0.01 1.5e-01 5.4e-03 1.9e-02 6.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.30.51.91.41.0-1.1-1.0-0.4-0.30.30.30.60.2-0.80.91.0-0.8-0.4-1.4-0.3-0.4-0.40.30.1
Area under the delay curve0.10.10.7-0.3-0.60.20.20.20.2-0.2-0.20.60.0-0.10.10.1-0.30.10.0-0.4-0.5-0.60.80.7
BMI with tail0.82.610.63.23.0-2.4-2.1-1.5-1.51.61.50.9-1.4-1.11.11.0-1.1-1.8-1.00.30.50.5-1.2-1.1
BMI without tail2.34.818.94.33.9-3.4-2.9-2.2-2.22.22.21.7-2.2-1.51.51.5-1.4-2.2-1.10.20.50.5-1.3-1.2
Body weight0.73.011.83.43.0-2.8-2.5-1.5-1.51.51.41.4-1.0-1.61.51.4-1.8-1.6-1.9-0.3-0.2-0.2-0.3-0.4
Weight adjusted by age0.70.73.40.30.40.40.40.10.1-0.1-0.0-1.1-0.10.8-0.8-0.80.8-0.2-0.01.21.41.4-1.8-1.6
Bone surface0.71.22.31.41.5-1.4-1.4-1.1-1.11.11.01.1-0.7-1.21.21.2-1.2-1.1-0.7-0.8-0.8-0.80.50.5
Bone volume0.91.63.61.91.7-1.7-1.6-1.1-1.11.11.01.4-0.8-1.41.41.5-1.4-1.0-1.3-0.8-0.9-0.80.60.5
Breakpoint value in progressive ratio session3.43.84.9-1.4-2.22.12.22.22.2-2.2-2.2-1.91.72.1-2.2-2.22.22.0-0.21.91.71.7-1.3-1.6
Number of licking bursts1.11.37.8-2.8-1.81.71.30.30.3-0.2-0.2-0.70.80.4-0.4-0.40.30.61.5-0.9-1.0-1.01.21.4
Context. condit. distance diff. score0.60.81.2-0.8-0.81.01.00.80.8-0.8-0.7-1.00.41.0-1.1-1.11.00.90.01.00.90.9-0.9-0.9
Locomotion velocity, session 10.40.41.00.10.1-0.4-0.5-0.2-0.20.20.10.7-0.0-0.80.80.8-0.80.0-0.6-0.9-1.0-1.01.01.0
Locomotion distance, session 10.20.21.31.20.6-0.5-0.40.20.3-0.3-0.3-0.00.3-0.20.10.1-0.1-0.1-1.00.50.40.4-0.5-0.6
Locomotion velocity, session 20.30.31.0-0.2-0.40.1-0.00.00.0-0.1-0.10.10.7-0.50.60.5-0.50.1-0.7-0.7-0.9-0.91.00.9
Locomotion distance, session 20.91.33.31.81.5-1.5-1.5-0.9-0.80.80.71.0-0.3-1.41.41.4-1.3-0.9-1.4-0.8-0.8-0.80.60.6
Locomotion velocity, session 30.10.10.40.70.4-0.4-0.4-0.3-0.30.30.30.1-0.2-0.30.30.2-0.3-0.4-0.4-0.1-0.1-0.10.00.0
Locomotion distance, session 31.21.32.90.41.1-0.8-1.0-1.5-1.51.51.51.0-1.7-1.01.01.0-1.0-1.30.6-1.1-1.0-1.00.60.9
Stereotopy head waving bouts, day 31.01.12.2-0.8-1.21.11.21.31.3-1.3-1.3-1.31.51.0-1.0-1.01.10.9-0.01.00.80.8-0.6-0.8
Stereotopy head waving duration, day 31.01.22.8-0.5-1.11.01.11.41.4-1.4-1.4-1.31.71.0-0.9-1.01.10.8-0.31.10.90.9-0.6-0.9
Locomotion velocity, session 71.82.05.61.11.7-1.2-1.4-2.0-2.02.02.01.3-2.4-1.21.31.3-1.3-1.30.4-1.0-0.9-0.80.30.7
Locomotion distance, session 70.81.01.70.10.9-0.6-0.9-1.2-1.21.21.11.0-1.1-1.01.21.1-1.1-0.40.0-1.3-1.1-1.10.81.2
Stereotopy head waving bouts, day 70.10.10.40.5-0.10.00.10.50.5-0.5-0.6-0.30.40.2-0.2-0.30.1-0.1-0.70.50.40.4-0.3-0.5
Stereotopy head waving duration, day 70.30.41.91.41.0-0.7-0.6-0.2-0.20.20.20.1-0.5-0.10.10.0-0.2-1.2-0.30.50.50.5-0.7-0.8
Locomotion velocity, session 80.10.10.60.1-0.20.10.00.30.3-0.3-0.3-0.30.6-0.20.20.1-0.20.4-0.8-0.1-0.2-0.20.20.2
Locomotion distance, session 80.10.11.10.50.3-0.1-0.2-0.00.0-0.0-0.0-0.10.1-0.20.20.2-0.20.1-1.00.20.00.0-0.2-0.2
Degree of sensitization distance0.90.93.0-0.2-0.90.50.71.31.3-1.3-1.4-0.61.70.6-0.5-0.50.61.6-1.30.70.50.5-0.1-0.5
Degree of sensitization stereotypy0.40.51.71.31.0-0.9-0.9-0.5-0.50.50.50.6-0.7-0.70.60.6-0.8-1.0-0.7-0.2-0.2-0.20.00.0
Conditioned locomotion0.10.21.2-0.8-0.00.50.3-0.3-0.30.30.3-0.3-0.50.2-0.4-0.30.2-0.21.1-0.2-0.0-0.0-0.20.1
Cocaine response after cond. corrected0.10.10.4-0.5-0.40.30.20.10.1-0.1-0.20.10.2-0.0-0.2-0.00.10.60.2-0.3-0.3-0.30.40.4
Cocaine response after cond. not corrected0.20.30.60.30.5-0.6-0.6-0.6-0.60.60.60.8-0.6-0.50.40.5-0.4-0.00.3-0.6-0.5-0.50.40.5
Cocaine response before conditioning2.12.64.51.82.1-2.0-2.0-1.9-1.91.91.91.9-1.9-1.51.71.6-1.5-1.9-0.2-1.1-0.9-0.90.50.7
Saline control response0.30.40.6-0.3-0.50.50.60.60.6-0.6-0.6-0.40.20.7-0.7-0.70.8-0.10.40.80.80.8-0.6-0.8
Bone: connectivity density0.10.20.80.90.9-0.7-0.6-0.4-0.40.40.40.3-0.2-0.30.40.4-0.3-0.6-0.20.00.10.1-0.3-0.3
Bone: cortical apparent density0.10.10.8-0.9-0.70.40.30.10.1-0.1-0.00.20.10.10.10.10.1-0.0-0.2-0.4-0.4-0.50.70.6
Bone: cortical area2.02.97.02.62.3-2.4-2.3-1.5-1.51.51.41.8-0.9-2.01.92.0-2.0-1.3-1.5-1.2-1.2-1.20.90.8
Bone: cortical porosity0.30.31.20.90.6-0.3-0.2-0.0-0.00.10.1-0.3-0.20.3-0.4-0.40.3-0.10.10.80.90.9-1.1-1.1
Bone: cortical porosity0.60.72.10.40.10.30.40.50.5-0.4-0.4-0.80.10.8-0.9-0.90.90.20.31.21.31.3-1.5-1.4
Bone: cortical thickness1.32.13.71.91.3-1.9-1.8-0.8-0.80.70.71.60.0-1.91.81.9-1.9-0.3-1.8-1.3-1.5-1.51.61.3
Bone: cortical thickness1.21.44.00.80.2-1.1-1.0-0.3-0.20.20.11.30.6-1.41.41.5-1.40.4-1.7-1.3-1.6-1.62.01.5
Bone: cortical tissue density0.10.10.8-0.9-0.70.50.40.10.1-0.1-0.10.10.10.10.10.10.20.0-0.2-0.4-0.4-0.40.60.6
Condit. Reinf. active minus inactive responses0.50.61.1-0.4-0.50.60.70.80.8-0.8-0.7-0.80.50.8-0.7-0.71.10.3-0.01.00.90.9-0.9-1.0
Condit. Reinf. active-inactive response ratio0.50.51.4-0.2-0.10.40.50.40.3-0.3-0.3-0.60.10.9-0.7-0.71.0-0.40.21.01.11.1-1.2-1.2
Condit. Reinf. active responses0.40.50.9-0.3-0.60.60.70.90.9-0.9-0.9-0.80.70.7-0.7-0.70.80.4-0.20.80.70.7-0.6-0.7
Condit. Reinf. inactive responses0.10.10.5-0.0-0.30.20.30.60.6-0.6-0.7-0.50.60.0-0.3-0.3-0.00.4-0.30.1-0.0-0.00.10.0
Incentive salience index mean0.10.10.80.10.4-0.1-0.1-0.4-0.40.40.4-0.0-0.70.1-0.1-0.00.3-0.90.30.20.30.3-0.5-0.4
Condit. Reinf. lever presses0.30.31.9-0.30.50.1-0.1-0.7-0.80.80.80.1-1.20.0-0.1-0.10.1-1.40.9-0.10.10.1-0.5-0.1
Condit. Reinf. active minus inactive responses1.11.43.60.6-0.20.40.61.11.1-1.1-1.1-1.00.91.1-1.2-1.11.2-0.7-0.51.81.71.7-1.7-1.9
Condit. Reinf. active-inactive response ratio1.71.83.5-0.0-0.70.81.11.41.3-1.3-1.3-1.31.01.5-1.5-1.41.50.30.31.91.81.8-1.6-1.9
Condit. Reinf. active responses0.50.72.10.60.10.10.30.50.5-0.4-0.4-0.70.40.7-0.8-0.70.8-1.4-0.31.31.21.2-1.3-1.4
Condit. Reinf. inactive responses1.11.36.31.01.3-1.1-1.2-1.4-1.41.41.40.9-1.1-1.00.91.0-1.0-2.5-0.2-0.8-0.7-0.70.30.5
Condit. Reinf. lever presses0.40.51.61.20.9-0.7-0.40.10.1-0.0-0.1-0.10.00.2-0.3-0.30.2-1.2-0.10.91.01.0-1.2-1.3
Condit. Reinf. lever reinforcers received0.81.12.70.2-0.20.50.70.80.8-0.8-0.7-1.00.61.1-1.1-1.11.1-1.00.01.51.51.5-1.6-1.6
Conditioned reinforcement - actives0.30.31.50.4-0.2-0.5-0.40.40.4-0.4-0.40.50.4-0.20.20.2-0.31.0-1.2-0.3-0.6-0.61.00.6
Conditioned reinforcement - inactives0.30.31.4-0.7-0.80.20.20.20.2-0.2-0.20.00.6-0.10.10.1-0.11.1-0.5-0.6-0.8-0.81.20.9
Conditioned locomotion0.00.10.3-0.2-0.40.20.20.20.2-0.3-0.30.00.20.1-0.1-0.10.10.6-0.2-0.1-0.2-0.20.30.2
Patch foraging indifference point 0 sec0.71.22.40.7-0.40.10.51.41.4-1.4-1.4-0.91.50.8-0.8-1.00.8-0.4-1.21.51.31.3-1.0-1.5
Patch foraging indifference point AUC0.60.71.61.00.8-1.1-1.0-0.7-0.70.70.70.8-0.3-0.91.00.9-1.0-0.9-1.3-0.6-0.7-0.70.70.5
Delay disc. indifference point, 0s delay3.03.34.91.01.2-1.6-1.7-1.7-1.71.71.62.1-1.4-2.12.02.0-2.2-1.7-0.8-2.1-2.2-2.22.12.1
Delay disc. indifference point, 16s delay3.53.57.8-2.4-2.82.42.32.32.3-2.3-2.2-1.62.11.9-1.9-1.91.92.30.41.10.80.8-0.2-0.5
Delay disc. indifference point, 2s delay3.84.26.62.62.4-2.5-2.5-2.1-2.12.02.02.4-1.8-2.22.22.2-2.5-1.9-1.1-1.7-1.6-1.61.31.3
Delay disc. indifference point, 24s delay1.61.55.1-2.3-2.01.81.71.31.3-1.3-1.3-1.01.11.2-1.2-1.21.10.31.30.20.20.10.20.2
Delay disc. indifference point, 4s delay0.70.72.60.4-0.1-0.5-0.5-0.2-0.20.20.21.3-0.1-0.90.80.8-1.1-0.3-0.7-1.0-1.3-1.31.61.3
Delay disc. indifference point, 8s delay0.60.61.6-0.00.1-0.4-0.5-0.6-0.60.60.61.3-0.7-0.80.70.7-0.8-0.20.1-1.0-1.1-1.11.21.2
Indifference point function ln k0.10.10.30.60.4-0.4-0.30.00.0-0.1-0.10.4-0.0-0.20.20.2-0.30.6-0.3-0.0-0.0-0.0-0.0-0.1
Indifference point function log k0.10.10.30.60.4-0.4-0.30.00.0-0.1-0.10.4-0.0-0.20.20.2-0.30.6-0.3-0.0-0.0-0.0-0.0-0.1
Patch foraging total patch changes 0 sec0.91.52.90.7-0.40.10.51.51.5-1.5-1.5-0.91.61.0-1.0-1.10.9-0.2-1.31.71.51.5-1.2-1.7
Patch foraging total patch changes 12 sec0.20.21.30.40.3-0.1-0.00.10.1-0.1-0.1-0.70.40.2-0.2-0.20.2-1.1-0.30.60.60.6-0.7-0.7
Patch foraging total patch changes 18 sec0.10.10.4-0.1-0.40.00.10.40.4-0.4-0.4-0.10.50.10.0-0.10.1-0.7-0.30.10.00.00.2-0.0
Patch foraging total patch changes 24 sec0.30.31.90.80.2-0.5-0.20.50.5-0.5-0.5-0.31.00.10.2-0.10.1-0.7-1.40.60.50.5-0.3-0.7
Patch foraging total patch changes 6 sec1.72.57.2-0.4-1.70.91.32.32.3-2.3-2.3-1.32.71.3-1.3-1.41.20.5-1.61.61.21.2-0.4-1.2
Patch foraging time to switch 0 sec0.71.05.4-2.0-0.91.71.30.20.2-0.1-0.1-1.3-0.31.0-1.0-1.01.1-0.32.30.20.40.4-0.7-0.1
Patch foraging water rate 0 sec0.10.10.50.70.5-0.5-0.4-0.2-0.20.20.20.30.1-0.20.10.2-0.30.2-0.30.00.00.1-0.1-0.2
Patch foraging water rate 12 sec0.30.42.41.60.4-1.0-0.50.60.6-0.6-0.60.50.7-0.10.20.2-0.10.8-0.90.60.50.5-0.2-0.7
Patch foraging water rate 18 sec0.50.62.60.6-0.10.00.30.90.8-0.9-0.8-0.50.80.6-0.6-0.60.51.6-0.51.00.90.9-0.8-1.1
Patch foraging water rate 24 sec0.50.71.31.10.6-1.1-1.0-0.7-0.70.60.71.1-0.2-1.00.91.0-1.00.2-0.4-0.7-0.9-0.91.00.8
Patch foraging water rate 6 sec0.20.31.40.4-0.3-0.4-0.20.40.4-0.4-0.40.40.8-0.30.50.4-0.41.2-1.0-0.2-0.4-0.40.80.4
Seeking ratio, delayed vs. immediate footshock0.00.00.10.0-0.1-0.0-0.0-0.1-0.10.10.10.1-0.3-0.00.00.00.30.1-0.20.00.00.00.10.0
Distance traveled before self-admin0.60.71.80.10.1-0.6-0.6-0.6-0.60.50.50.9-0.0-1.00.90.9-0.8-0.8-0.4-1.0-1.2-1.21.41.2
Distance traveled after self-admin3.13.45.41.51.8-2.1-2.1-1.8-1.81.81.72.3-1.6-2.22.12.1-2.2-1.2-1.0-1.9-1.8-1.81.71.7
Extensor digitorum longus weight4.417.425.94.55.1-5.0-5.0-4.7-4.74.74.64.8-4.2-4.54.34.2-4.5-4.4-1.7-3.5-3.2-3.22.22.6
Bone: elastic displacement0.60.72.2-0.7-1.20.80.91.11.1-1.2-1.2-0.71.50.6-0.6-0.60.61.4-0.50.40.20.20.3-0.1
Bone: elastic work0.20.30.90.70.4-0.7-0.6-0.2-0.20.20.20.70.1-0.60.60.6-0.5-0.1-0.9-0.4-0.5-0.50.60.4
Bone: endosteal estimation1.02.35.41.92.3-1.8-1.8-1.9-1.91.91.91.5-2.1-1.21.21.2-1.3-2.2-0.2-0.6-0.4-0.3-0.30.1
Bone: endosteal perimeter1.12.44.71.42.0-1.5-1.7-2.0-2.02.02.01.4-2.0-1.41.31.4-1.5-2.20.4-1.2-1.0-1.00.30.8
Epididymis fat weight0.20.51.71.30.7-0.5-0.30.30.3-0.3-0.3-0.50.40.2-0.1-0.20.30.2-1.31.01.01.0-1.1-1.3
Delta time in closed arm before/after self-admin0.30.31.6-0.40.30.2-0.0-0.7-0.80.80.80.0-1.00.00.00.0-0.1-0.91.3-0.3-0.1-0.1-0.30.2
Delta time in open arm before/after self-admin0.80.73.21.81.2-1.4-1.2-0.4-0.40.40.30.7-0.1-0.90.90.9-0.9-0.1-1.7-0.1-0.2-0.20.2-0.1
Diff in mean of infusions in LGA sessions2.32.54.8-0.7-1.61.41.62.02.0-2.0-2.0-1.51.81.5-1.6-1.61.52.2-1.01.61.31.3-0.9-1.3
Delay discount exponential model param0.10.10.40.40.6-0.3-0.2-0.2-0.20.20.2-0.4-0.0-0.00.00.00.1-0.1-0.20.30.40.4-0.7-0.5
Extinction: sum of active levers before priming0.10.10.3-0.5-0.40.40.30.10.1-0.1-0.0-0.1-0.10.1-0.2-0.20.1-0.3-0.0-0.1-0.1-0.20.20.3
Active lever presses in extinction session 61.21.11.6-0.2-0.80.81.01.31.3-1.3-1.3-1.21.21.0-1.2-1.21.00.6-0.71.21.21.2-0.9-1.2
Bone: final force3.15.112.13.53.1-3.2-3.0-2.2-2.12.12.12.3-1.6-2.52.52.5-2.5-1.9-2.0-1.4-1.4-1.30.90.8
Bone: final moment2.23.510.23.22.7-2.8-2.6-1.7-1.71.61.61.9-1.2-2.02.12.1-2.1-1.5-1.9-1.0-1.0-1.00.60.5
Food consumed during 24 hour testing period1.72.02.91.61.6-1.7-1.7-1.5-1.51.51.51.6-1.4-1.51.61.5-1.6-1.0-1.2-1.1-1.2-1.10.90.9
Glucose0.20.32.1-0.0-0.70.30.40.70.7-0.7-0.7-0.70.90.3-0.3-0.30.21.4-0.40.50.20.20.1-0.2
Heart weight0.30.41.80.0-0.60.10.30.90.9-1.0-1.0-0.21.10.0-0.1-0.10.11.3-0.80.2-0.1-0.10.50.1
Delay discount hyperbolic model param0.20.20.70.10.30.10.10.10.1-0.0-0.0-0.70.10.3-0.3-0.30.50.10.10.60.70.7-0.9-0.7
Intermittent access intake day 1-15 change1.11.13.1-1.1-0.1-0.0-0.3-0.9-0.90.90.90.8-0.7-0.90.90.9-0.7-0.40.8-1.6-1.5-1.51.51.8
Intermittent access intake escalation0.90.82.6-0.9-0.1-0.1-0.3-0.8-0.80.80.80.7-0.5-0.80.80.8-0.6-0.20.6-1.4-1.4-1.41.51.6
Intermittent access intake escalation 21.11.12.9-1.0-0.1-0.0-0.3-1.0-1.01.01.00.8-0.7-1.11.11.1-0.6-0.20.5-1.5-1.5-1.51.51.7
Intermitt. access day 1 inactive lever presses0.30.31.2-0.2-0.1-0.3-0.3-0.4-0.40.30.30.40.1-0.70.70.7-0.40.2-0.5-0.8-0.9-0.91.11.0
Intermitt. access day 15 inactive lever presses1.21.32.10.71.1-1.1-1.2-1.4-1.41.41.40.8-0.6-1.41.41.4-1.2-0.8-0.7-1.1-1.1-1.10.91.0
Intermitt. access escalation Index0.40.31.10.80.9-0.7-0.7-0.5-0.50.50.50.9-1.0-0.40.40.4-0.2-0.60.3-0.2-0.0-0.0-0.1-0.1
Intermittent access day 1 total infusions0.60.61.71.10.2-0.30.00.60.6-0.6-0.6-0.70.90.6-0.6-0.60.50.7-1.01.21.11.1-1.0-1.3
Intermittent access day 15 total infusions0.10.10.40.1-0.1-0.10.00.20.2-0.2-0.2-0.40.60.1-0.1-0.10.10.6-0.40.10.00.00.1-0.1
Intermittent access terminal intake (last 3 days)0.10.10.50.2-0.1-0.10.10.30.3-0.3-0.3-0.30.60.1-0.1-0.10.20.7-0.50.30.20.2-0.0-0.2
Intermittent access total infusions0.30.30.80.80.1-0.3-0.10.50.5-0.5-0.5-0.40.70.4-0.4-0.40.30.9-0.90.70.60.6-0.5-0.8
Intermittent access day 1 locomotion0.70.81.91.00.1-0.20.10.80.8-0.8-0.8-1.01.20.6-0.6-0.60.50.8-1.11.31.11.2-1.0-1.4
Intermittent access day 15 total locomotion2.52.74.8-1.1-1.91.41.62.12.1-2.1-2.1-1.72.21.7-1.7-1.71.72.0-0.41.51.21.2-0.5-1.1
Intermittent access total locomotion1.71.93.50.5-0.60.50.81.51.5-1.5-1.4-1.61.81.3-1.3-1.31.21.4-1.11.91.71.7-1.4-1.9
Intermittent access standard deviation0.80.81.60.20.5-0.7-0.8-0.9-0.90.90.90.6-0.2-1.11.11.1-1.0-0.3-0.7-1.1-1.3-1.31.21.2
Left kidney weight1.64.611.63.43.1-3.2-2.9-2.1-2.12.02.02.3-1.4-2.32.22.1-2.3-1.9-2.4-1.1-1.0-1.00.70.5
Right kidney weight2.05.713.33.63.3-3.5-3.2-2.3-2.32.32.32.7-1.9-2.52.52.4-2.6-2.1-2.4-1.2-1.2-1.10.80.6
Cocaine induced anxiety0.20.20.4-0.4-0.20.40.40.30.3-0.3-0.3-0.60.40.6-0.6-0.60.30.30.50.30.40.4-0.5-0.4
Post-drug Anxiety0.60.71.7-0.4-1.00.60.71.21.2-1.2-1.2-0.71.20.8-0.8-0.80.61.3-0.40.50.30.30.1-0.3
Baseline Anxiety0.60.72.20.70.2-0.9-0.8-0.2-0.20.10.11.3-0.4-1.01.01.0-0.70.3-1.5-0.7-1.0-1.01.30.9
Tail length0.82.49.03.02.3-2.6-2.2-1.4-1.41.31.31.8-1.0-1.61.51.6-1.6-0.8-1.4-0.5-0.5-0.50.40.1
Length with tail0.30.92.61.41.0-1.4-1.3-0.6-0.60.50.51.0-0.0-1.11.01.0-1.3-0.3-1.6-0.7-0.8-0.80.90.6
Length without tail0.20.51.6-1.2-1.10.70.50.50.6-0.6-0.7-0.31.0-0.10.20.0-0.40.5-0.4-0.6-0.9-0.91.11.0
Times rat made contact with spout3.84.46.61.32.0-1.9-2.2-2.6-2.62.62.61.9-2.0-2.22.22.2-2.3-1.8-1.0-2.2-2.1-2.11.62.0
Lifetime Intake0.30.41.61.30.5-0.7-0.40.30.3-0.3-0.3-0.20.50.2-0.2-0.20.10.7-1.10.80.60.7-0.6-0.9
Liver weight, left0.20.41.20.40.30.00.10.30.3-0.3-0.3-0.3-0.30.6-0.8-0.80.40.20.30.81.01.0-1.1-1.0
Liver weight, right0.50.82.60.61.1-0.2-0.3-0.8-0.80.90.9-0.3-1.40.4-0.3-0.50.2-1.40.60.71.01.0-1.6-1.2
Locomotor activity0.20.41.30.00.10.20.30.20.2-0.2-0.2-0.5-0.10.6-0.6-0.60.5-1.10.70.80.90.9-1.0-1.0
Locomotor testing distance0.20.31.00.60.2-0.10.10.40.4-0.3-0.3-0.40.20.4-0.5-0.40.3-0.30.10.80.80.9-0.9-1.0
Locomotor testing rearing0.81.32.8-0.1-0.40.70.91.01.0-0.9-0.9-1.40.71.2-1.3-1.31.2-0.30.81.61.61.6-1.6-1.7
Locomotion in novel chamber0.60.72.30.90.3-0.10.20.60.5-0.5-0.5-0.60.10.8-0.8-0.80.7-0.1-0.41.31.41.4-1.4-1.5
Locomotion in novel chamber post-restriction2.02.53.6-0.4-1.21.21.41.91.8-1.9-1.8-1.91.71.6-1.7-1.61.31.3-0.61.91.71.7-1.4-1.7
Fecal boli incidents, locomotor time 11.31.42.9-1.1-0.51.31.20.90.9-0.9-0.8-1.20.01.7-1.3-1.31.40.31.61.21.41.4-1.7-1.3
Change in fecal boli incidents, locomotor task0.60.52.40.9-0.7-0.20.21.01.0-1.0-1.0-0.11.60.2-0.2-0.2-0.00.5-1.50.50.10.10.5-0.2
Time >=10cm from walls, locomotor time 10.80.81.30.80.8-0.9-1.0-0.9-0.90.80.80.5-0.1-1.21.01.0-1.10.0-1.0-0.9-1.0-1.00.80.8
Bouts of movement, locomotor time 12.02.24.6-2.1-1.82.01.91.31.3-1.3-1.2-1.50.81.8-1.7-1.71.80.71.61.01.11.1-0.9-0.8
Total resting periods, locomotor time 12.22.45.4-2.3-1.92.22.01.41.3-1.3-1.3-1.40.61.9-1.8-1.81.80.52.01.01.21.1-1.0-0.8
Rest time, locomotor task time 10.40.41.5-1.2-0.60.60.3-0.3-0.20.30.3-0.20.0-0.10.10.1-0.3-0.90.8-0.9-1.0-1.01.01.2
Distance moved, locomotor task time 10.40.53.01.70.9-1.1-0.8-0.2-0.20.20.10.5-0.0-0.40.30.3-0.2-0.1-1.30.60.60.6-0.5-0.8
Vertical activity count, locomotor time 12.32.45.22.21.6-2.2-2.0-1.3-1.31.21.21.9-0.7-1.91.81.8-1.6-0.0-2.3-1.0-1.2-1.21.20.9
Time >=10cm from walls, locomotor time 22.42.64.01.51.8-1.9-1.9-1.7-1.71.71.71.5-1.1-2.01.91.9-1.7-0.6-1.3-1.5-1.5-1.41.21.2
Bouts of movement, locomotor time 20.60.62.50.30.90.1-0.0-0.6-0.60.60.6-0.5-1.30.2-0.3-0.30.3-1.50.90.60.90.9-1.6-1.0
Total resting periods, locomotor time 20.60.62.90.51.1-0.1-0.2-0.7-0.70.80.7-0.3-1.40.0-0.1-0.10.2-1.70.80.50.80.8-1.5-0.9
Rest time, locomotor task time 20.10.10.3-0.1-0.30.20.20.30.3-0.3-0.3-0.30.60.1-0.1-0.10.2-0.2-0.30.1-0.0-0.00.20.0
Distance moved, locomotor task time 22.42.84.20.91.3-1.6-1.7-1.9-1.91.81.82.0-1.4-2.01.91.9-1.6-1.5-0.7-1.7-1.7-1.71.61.7
Vertical activity count, locomotor time 22.52.74.41.00.9-1.6-1.7-1.5-1.51.41.41.9-0.7-2.12.02.0-1.6-0.4-1.7-1.8-2.0-2.02.11.9
Light reinforcement 11.32.45.4-0.5-1.21.41.51.61.6-1.6-1.6-2.31.71.6-1.8-1.61.61.00.01.81.71.7-1.6-1.6
Light reinforcement 21.01.32.00.0-0.60.70.91.31.3-1.2-1.3-1.31.31.2-1.1-1.11.11.4-0.41.41.41.4-1.3-1.4
Bone: marrow area1.02.14.91.82.2-1.7-1.7-1.8-1.81.81.91.4-2.0-1.11.11.2-1.2-2.1-0.1-0.6-0.4-0.3-0.20.1
Bone: maximum diameter1.12.15.02.22.2-2.0-1.9-1.6-1.61.61.61.3-1.4-1.41.41.5-1.5-1.5-0.7-0.7-0.6-0.60.20.3
Bone: maximum force2.84.910.23.22.9-3.0-2.9-2.1-2.12.12.02.4-1.6-2.42.52.5-2.5-1.9-2.0-1.5-1.5-1.41.01.0
Bone: maximum moment1.93.38.22.92.5-2.6-2.4-1.7-1.71.61.62.0-1.2-2.02.12.0-2.0-1.5-1.9-1.1-1.1-1.10.70.6
Mean time between licks in bursts0.10.21.1-0.40.10.40.3-0.2-0.20.20.2-0.6-0.40.4-0.4-0.40.4-0.31.10.10.30.3-0.6-0.2
Mean num. licks in bursts2.93.410.93.32.8-2.8-2.5-1.8-1.81.71.72.0-1.9-1.81.81.8-1.8-1.3-2.2-0.6-0.5-0.50.10.0
Cd content in liver4.85.38.5-2.5-2.92.72.82.62.6-2.6-2.5-2.01.72.7-2.7-2.72.71.10.72.22.12.1-1.3-1.7
Co content in liver1.01.13.2-0.6-1.40.70.91.51.5-1.6-1.6-0.51.80.7-0.5-0.50.71.7-1.40.60.30.30.3-0.2
Cu content in liver0.20.21.60.7-0.1-0.3-0.00.60.6-0.6-0.6-0.40.90.0-0.1-0.10.1-0.0-1.30.50.30.3-0.0-0.4
Fe content in liver0.50.61.9-0.9-1.20.60.50.90.9-0.9-1.0-0.41.40.0-0.1-0.10.00.8-0.6-0.4-0.6-0.71.10.8
K content in liver0.10.10.40.20.10.10.1-0.1-0.10.10.2-0.2-0.30.3-0.2-0.20.3-0.40.10.50.50.5-0.6-0.5
Mg content in liver1.21.23.4-0.4-0.30.90.90.60.6-0.5-0.5-1.20.11.3-1.2-1.21.4-0.11.31.41.61.6-1.9-1.6
Mn content in liver0.60.71.80.40.9-0.7-0.8-1.2-1.21.21.20.9-1.3-0.70.80.8-0.6-1.10.2-0.6-0.5-0.50.20.4
Na content in liver4.34.58.92.33.0-2.4-2.5-2.8-2.82.82.81.7-2.5-2.22.02.1-2.2-1.4-0.4-1.6-1.4-1.30.51.1
Rb content in liver3.23.96.2-0.8-2.01.62.02.52.5-2.5-2.5-2.02.32.0-2.1-2.12.11.70.12.21.91.9-1.3-1.9
Se content in liver0.40.50.80.30.6-0.6-0.7-0.8-0.80.80.80.6-0.7-0.80.90.9-0.8-0.1-0.3-0.9-0.8-0.80.60.8
Sr content in liver0.80.72.50.81.0-0.9-0.8-1.2-1.21.21.30.8-1.6-0.50.70.7-0.5-0.60.3-0.2-0.1-0.1-0.10.0
Zn content in liver0.91.03.81.91.9-1.5-1.3-0.9-0.80.90.80.6-0.9-0.80.80.8-0.7-1.4-0.4-0.00.20.2-0.6-0.5
Bone: minimum diameter1.22.24.82.02.2-1.9-1.9-1.7-1.71.71.71.5-1.6-1.51.41.4-1.6-1.8-0.2-0.9-0.8-0.80.20.5
Time in familiar zone, hab. session 10.30.31.4-0.5-1.00.40.50.70.7-0.8-0.7-0.10.80.2-0.1-0.20.11.2-0.50.1-0.1-0.10.60.2
Time in novel zone, hab. session 10.20.20.80.50.9-0.3-0.3-0.4-0.40.40.4-0.2-0.40.0-0.1-0.10.1-0.80.40.20.40.4-0.8-0.5
Total zone transitions, hab. session 11.01.45.42.21.3-1.7-1.5-0.4-0.40.30.31.00.3-1.41.41.4-1.5-0.6-2.3-0.5-0.7-0.70.70.4
Total locomotion distance, hab. session 11.72.310.93.31.9-2.4-2.0-0.6-0.50.50.41.50.0-1.61.61.6-1.4-1.0-3.3-0.2-0.4-0.40.4-0.1
Locomotion velocity, hab. session 11.11.58.83.01.6-1.9-1.6-0.3-0.30.30.21.00.1-1.11.11.1-0.9-0.7-2.80.3-0.00.0-0.1-0.5
Time in familiar zone, hab. session 20.20.20.50.70.5-0.7-0.6-0.3-0.30.30.20.30.1-0.60.50.4-0.6-0.1-0.5-0.4-0.4-0.40.40.3
Time in novel zone, hab. session 20.20.20.4-0.3-0.30.40.50.50.5-0.5-0.4-0.30.10.6-0.5-0.50.60.30.30.60.70.7-0.6-0.6
Total zone transitions, hab. session 20.60.74.81.91.0-1.3-1.0-0.2-0.10.10.10.40.4-0.80.90.9-0.8-0.6-2.20.1-0.1-0.00.0-0.3
Total locomotion distance, hab. session 21.21.66.62.41.4-1.8-1.6-0.7-0.60.60.51.2-0.1-1.51.51.4-1.3-0.5-2.6-0.4-0.7-0.70.70.3
Locomotion velocity, hab. session 21.41.96.82.61.7-2.0-1.8-0.9-0.90.80.81.2-0.3-1.61.61.5-1.5-0.7-2.6-0.5-0.7-0.70.60.3
Novel to familiar place preference ratio0.30.31.2-0.8-0.80.50.50.60.6-0.6-0.7-0.10.90.1-0.0-0.00.21.1-0.8-0.2-0.3-0.40.60.4
Novelty place preference0.40.41.3-0.8-0.80.50.40.40.5-0.5-0.50.10.9-0.20.20.1-0.11.1-0.8-0.5-0.7-0.70.90.8
Time in novel zone, NPP test0.40.41.8-0.8-0.90.60.50.70.8-0.8-0.8-0.21.10.1-0.1-0.10.21.3-0.9-0.1-0.3-0.30.60.4
Total zone transitions, NPP test0.60.83.11.81.1-1.3-1.2-0.5-0.40.40.40.9-0.1-1.01.11.1-1.0-0.6-1.6-0.3-0.4-0.40.40.2
Total locomotion distance, NPP test1.11.54.11.91.2-1.6-1.5-0.7-0.60.60.51.5-0.2-1.51.61.5-1.3-0.7-2.0-0.8-1.0-1.01.00.7
Locomotion velocity, NPP test1.01.43.41.81.1-1.5-1.4-0.7-0.70.60.61.5-0.3-1.51.51.5-1.3-0.7-1.8-0.9-1.1-1.11.10.8
Intraocular pressure0.00.10.30.50.5-0.3-0.30.10.1-0.1-0.1-0.20.3-0.10.10.20.1-0.00.10.20.30.3-0.4-0.4
Delta distance traveled before/after self-admin0.60.62.11.31.4-1.1-1.1-0.8-0.80.80.70.8-1.1-0.70.70.7-0.9-0.3-0.5-0.4-0.2-0.2-0.20.0
Delta ambulatory time before/after self-admin0.70.81.81.31.3-1.2-1.2-0.9-0.80.80.81.0-1.1-0.90.90.9-1.1-0.5-0.5-0.6-0.5-0.50.20.3
Parametrial fat weight0.51.05.52.31.6-1.8-1.4-0.6-0.60.60.61.2-0.8-0.70.50.7-0.8-0.2-1.30.30.30.3-0.3-0.6
Pavlov. Cond. lever latency0.91.24.5-0.6-1.60.40.61.41.4-1.5-1.5-0.02.1-0.10.30.2-0.21.3-1.5-0.2-0.7-0.71.60.9
Pavlov. Cond. magazine entry latency1.41.85.51.62.3-1.1-1.1-1.7-1.71.81.80.2-2.3-0.20.10.1-0.0-1.31.30.51.01.0-1.9-1.2
Pavlov. Cond. change in total contacts2.42.610.70.62.1-0.9-1.2-2.4-2.52.52.60.9-3.3-0.80.70.7-0.6-2.11.8-0.8-0.3-0.2-0.80.2
Pavlov. Cond. index score1.51.97.10.92.0-0.6-0.7-1.7-1.71.81.90.0-2.70.1-0.2-0.20.3-1.72.00.41.01.0-2.0-1.2
Pavlov. Cond. latency score1.31.65.80.91.8-0.6-0.7-1.5-1.61.61.70.0-2.40.1-0.2-0.20.3-1.61.80.41.01.0-1.9-1.1
Pavlov. Cond. lever contacts1.61.97.10.92.1-0.7-0.9-1.9-1.92.02.00.3-2.7-0.20.00.0-0.1-2.11.60.10.60.6-1.6-0.8
Pavlov. Cond. magazine entry number1.51.97.2-0.9-2.10.81.01.91.9-2.0-2.0-0.42.70.3-0.2-0.30.21.8-2.00.1-0.5-0.51.40.6
Pavlov. Cond. intertrial magazine entries1.72.05.0-1.0-1.91.21.42.02.0-2.1-2.1-0.92.21.1-1.1-1.10.92.1-1.20.90.50.50.2-0.4
Pavlov. Cond. lever-magazine prob. diff.1.82.28.31.12.2-0.7-0.9-1.9-1.92.02.10.1-2.90.0-0.1-0.10.2-1.82.00.41.01.0-2.1-1.2
Pavlov. Cond. response bias1.92.39.00.82.2-0.8-1.1-2.2-2.22.32.30.4-3.0-0.40.30.3-0.3-2.12.0-0.20.40.4-1.5-0.5
Pavlov. Cond. lever latency0.20.21.3-1.1-0.80.80.60.10.0-0.0-0.0-0.1-0.20.2-0.1-0.10.20.10.6-0.4-0.5-0.50.60.7
Pavlov. Cond. magazine entry latency0.30.42.0-1.4-0.50.90.6-0.1-0.10.10.2-0.3-0.60.5-0.6-0.60.6-0.51.4-0.20.10.1-0.20.2
Pavlov. Cond. change in total contacts1.31.72.9-0.1-1.00.81.11.61.6-1.6-1.6-1.31.71.3-1.3-1.31.31.0-0.91.61.51.5-1.1-1.6
Pavlov. Cond. index score0.20.20.5-0.3-0.10.30.40.40.4-0.4-0.3-0.50.20.6-0.6-0.70.6-0.20.40.60.70.7-0.7-0.7
Pavlov. Cond. latency score0.10.10.3-0.20.10.10.20.10.1-0.1-0.1-0.2-0.10.4-0.3-0.40.3-0.30.40.30.40.4-0.5-0.4
Pavlov. Cond. lever contacts0.20.31.31.10.9-0.7-0.5-0.1-0.00.10.0-0.10.00.1-0.1-0.2-0.0-0.4-0.20.70.80.8-1.0-1.1
Pavlov. Cond. magazine entry number1.01.23.21.81.4-1.5-1.4-1.0-1.01.00.91.1-0.6-1.31.31.3-1.3-0.3-1.0-0.6-0.7-0.70.50.5
Pavlov. Cond. intertrial magazine entries0.81.14.02.01.7-1.4-1.2-1.1-1.11.11.10.5-1.0-0.70.50.7-0.6-1.7-0.30.20.30.4-0.7-0.6
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.5-0.20.50.50.30.3-0.3-0.3-0.50.10.7-0.7-0.80.7-0.30.60.60.70.7-0.8-0.7
Pavlov. Cond. response bias0.20.31.00.10.10.10.20.40.4-0.3-0.3-0.50.20.6-0.7-0.70.6-0.30.20.80.90.9-1.0-1.0
Time in closed arm before self-admin0.20.20.90.90.5-0.8-0.6-0.1-0.10.10.00.40.2-0.70.50.5-0.50.2-0.9-0.1-0.2-0.20.30.1
Time in closed arm after self-admin1.11.12.5-0.8-1.51.11.21.41.4-1.4-1.4-1.01.61.0-1.0-1.01.01.0-0.10.80.60.6-0.1-0.5
Time in open arm before self-admin0.80.83.0-1.7-1.21.51.30.50.5-0.4-0.4-0.9-0.01.2-1.0-1.01.20.51.30.40.40.4-0.4-0.2
Time in open arm after self-admin2.32.53.91.31.9-1.7-1.8-2.0-2.02.02.01.8-2.0-1.71.71.7-1.7-1.4-0.3-1.3-1.2-1.20.81.0
Bone: periosteal estimation1.93.98.42.82.9-2.6-2.6-2.1-2.12.12.12.1-1.9-2.01.92.0-2.1-2.2-1.0-1.1-1.0-1.00.40.6
Bone: periosteal perimeter0.71.13.21.71.8-1.4-1.3-1.2-1.21.21.20.8-1.2-0.90.80.8-1.0-1.4-0.2-0.3-0.2-0.2-0.3-0.1
Bone: post-yield work0.71.03.31.81.4-1.0-0.7-0.5-0.60.60.70.2-1.20.2-0.0-0.10.1-0.5-0.51.21.31.4-1.6-1.7
Progressive ratio test 1 active lever presses0.40.41.20.50.00.10.20.40.4-0.4-0.4-0.60.50.5-0.5-0.50.50.4-0.41.01.01.0-0.9-1.1
Progressive ratio test 1 breakpoint0.30.31.20.50.00.10.20.40.3-0.4-0.3-0.50.40.5-0.5-0.50.50.5-0.21.01.01.0-0.9-1.1
Progressive ratio test 1 inactive lever presses0.10.10.50.70.5-0.5-0.4-0.1-0.10.10.20.00.0-0.10.10.1-0.20.2-0.20.20.20.2-0.3-0.4
Progressive ratio test 2 active lever presses0.50.51.20.4-0.20.20.40.80.8-0.8-0.7-0.60.70.7-0.7-0.70.70.8-0.61.01.01.0-0.8-1.1
Progressive ratio test 2 breakpoint0.60.71.40.3-0.30.30.50.90.9-0.9-0.8-0.70.70.8-0.8-0.80.80.8-0.61.21.11.1-1.0-1.2
Progressive ratio test 2 inactive lever presses0.60.71.50.1-0.50.40.60.80.8-0.8-0.7-1.01.00.8-0.8-0.80.91.2-0.71.11.01.0-0.9-1.1
Incentive Sensitization - Responses0.40.40.9-0.1-0.20.40.50.50.5-0.5-0.4-0.40.10.7-0.7-0.70.70.30.10.90.90.9-0.9-0.9
Incentive Sensitization - Breakpoint0.40.41.0-0.0-0.30.40.50.60.5-0.5-0.5-0.50.20.7-0.7-0.70.70.4-0.00.91.01.0-1.0-1.0
Sum of active levers in priming session hrs 5-61.11.02.2-0.2-0.40.80.90.90.9-0.9-0.9-1.00.31.2-1.2-1.21.20.20.21.31.41.4-1.5-1.4
Progressive ratio0.80.92.00.1-0.90.60.81.31.3-1.2-1.2-0.51.01.0-0.8-0.90.61.4-0.91.10.90.9-0.5-0.9
Food seeking constrained by brief footshock0.50.61.7-1.2-1.31.00.90.90.9-0.9-0.9-0.41.00.5-0.4-0.50.60.9-0.4-0.1-0.2-0.20.50.4
Seeking ratio, punishment vs. effort0.30.41.2-0.10.7-0.4-0.5-0.9-0.90.80.80.3-0.7-0.60.50.6-0.3-1.10.5-0.7-0.5-0.50.20.5
Retroperitoneal fat weight1.03.46.70.6-0.70.71.12.01.9-2.0-1.9-2.02.01.7-1.9-1.91.61.8-1.22.52.42.4-2.1-2.6
Reaction time number correct1.01.42.2-1.2-1.11.41.41.01.0-1.0-0.9-1.50.71.5-1.4-1.41.31.20.81.11.21.2-1.1-1.0
Reaction time mean minus median0.10.20.90.40.4-0.5-0.5-0.4-0.50.40.50.4-0.2-0.50.40.5-0.3-0.9-0.4-0.3-0.3-0.30.30.3
Reaction time mean minus median AUC0.30.40.7-0.2-0.60.40.60.80.8-0.8-0.7-0.60.80.7-0.8-0.70.80.1-0.20.80.80.8-0.5-0.8
Reaction time num false alarms0.60.82.6-0.9-0.30.1-0.2-0.7-0.70.70.71.0-0.5-0.70.70.6-0.70.0-0.0-1.4-1.4-1.41.51.6
Reaction time num false alarms AUC0.30.41.2-0.9-0.20.2-0.1-0.6-0.60.60.60.6-0.5-0.40.50.3-0.40.10.2-0.9-0.9-1.00.91.1
Reaction time trials correct on left1.01.42.2-1.2-1.11.41.41.01.0-1.0-0.9-1.50.71.5-1.4-1.41.31.20.81.11.21.2-1.1-1.0
Reaction time trials on left1.01.52.3-1.2-1.11.41.41.11.0-1.0-1.0-1.50.71.5-1.4-1.51.31.20.81.21.21.2-1.2-1.1
Reaction time mean0.10.10.50.70.5-0.5-0.4-0.2-0.20.20.20.3-0.2-0.10.10.10.1-0.5-0.10.30.30.3-0.3-0.4
Reaction time mean AUC0.10.10.40.40.3-0.2-0.10.0-0.00.00.0-0.0-0.10.2-0.2-0.20.4-0.30.00.50.60.6-0.6-0.6
Median of all reaction times0.10.10.50.70.5-0.5-0.3-0.1-0.10.10.10.2-0.30.0-0.1-0.10.2-0.30.10.40.50.5-0.6-0.6
Reaction time omissions0.70.92.2-0.8-0.30.90.90.40.3-0.3-0.3-1.3-0.01.1-1.2-1.21.1-0.01.41.01.31.3-1.5-1.2
Reaction time false alarm rate1.11.53.2-0.10.5-0.7-0.9-1.2-1.21.21.21.5-1.0-1.31.31.2-1.2-0.7-0.2-1.7-1.7-1.71.61.8
Reaction time premature initiation rate2.43.26.41.41.9-1.9-2.0-2.1-2.12.02.01.7-1.5-2.01.82.0-1.8-2.5-0.1-1.7-1.6-1.61.21.4
Reaction time premature initiations0.81.12.50.51.1-0.9-1.0-1.4-1.41.41.40.8-1.1-1.11.01.1-1.0-1.60.5-1.0-0.9-0.90.60.9
Std. dev. reaction times0.10.10.40.60.3-0.4-0.30.00.0-0.0-0.00.00.2-0.10.10.10.1-0.6-0.40.20.20.3-0.2-0.4
Reaction time trials completed1.01.52.3-1.2-1.11.41.41.11.0-1.0-1.0-1.50.71.5-1.4-1.51.31.20.81.21.21.2-1.2-1.1
Reaction time trials AUC0.81.21.8-1.1-0.91.21.20.90.9-0.9-0.9-1.30.61.3-1.2-1.31.21.20.71.11.11.1-1.0-1.0
Run reversals in cocaine runway, females7.16.910.82.82.9-3.2-3.1-2.7-2.72.62.63.3-2.5-2.93.13.0-2.9-2.3-1.4-2.2-2.1-2.11.81.8
Run reversals in cocaine runway, males0.10.10.4-0.6-0.50.30.20.10.1-0.1-0.10.30.2-0.10.10.10.20.40.2-0.5-0.5-0.50.70.7
Latency to leave start box in cocaine runway1.61.73.5-0.4-1.10.91.11.81.8-1.8-1.9-1.41.71.1-1.2-1.21.41.5-0.81.31.11.1-0.7-1.1
Latency to leave start box in cocaine runway, F1.11.22.2-0.6-0.71.01.01.21.2-1.2-1.3-1.40.91.1-1.3-1.21.50.50.41.11.21.2-1.1-1.1
Latency to leave start box in cocaine runway, M1.01.03.7-0.1-1.20.40.71.41.5-1.5-1.5-0.41.70.5-0.5-0.50.51.9-1.40.60.30.30.3-0.3
Std. dev. time between licks in bursts0.30.31.30.10.40.20.2-0.2-0.20.20.2-0.7-0.40.5-0.6-0.60.60.30.70.60.80.8-1.1-0.8
Total sessions with >9 infusions2.12.35.82.42.1-2.3-2.1-1.5-1.51.41.41.7-1.2-1.71.71.7-1.6-0.6-1.3-0.8-0.8-0.80.60.4
Short access day 1 total inactive lever presses0.20.31.00.1-0.40.10.20.70.7-0.7-0.7-0.61.00.3-0.3-0.30.11.0-0.80.30.10.10.1-0.2
Short access day 10 total inactive lever presses0.30.31.3-0.9-0.80.30.20.10.2-0.2-0.2-0.10.6-0.20.20.20.00.4-0.3-0.7-0.9-0.91.21.0
Short access day 1 total infusions0.30.31.51.20.5-0.9-0.60.30.3-0.3-0.30.20.3-0.20.20.2-0.10.9-1.20.40.20.20.0-0.4
Short access day 10 total infusions0.50.51.81.31.1-1.2-1.0-0.7-0.70.70.70.7-0.5-0.80.80.8-0.7-0.1-0.8-0.1-0.1-0.10.1-0.1
Short access total infusions0.40.53.11.80.9-1.1-0.70.10.1-0.1-0.10.20.2-0.10.10.1-0.10.5-1.30.70.60.6-0.5-0.9
Short access day 1 locomotion0.10.10.60.40.1-0.5-0.30.10.1-0.1-0.10.10.4-0.30.30.3-0.20.5-0.7-0.0-0.1-0.10.40.1
Short access day 10 total locomotion0.40.52.31.51.1-0.8-0.6-0.3-0.30.30.3-0.30.1-0.10.10.1-0.4-0.4-0.80.70.80.8-1.1-1.1
Short access total locomotion1.11.12.81.50.2-0.40.01.01.0-1.0-1.0-0.91.20.7-0.7-0.70.61.0-1.61.61.41.4-1.1-1.7
One hour access (0.3 mA shock)0.50.62.31.50.8-0.6-0.30.20.2-0.2-0.1-0.20.10.4-0.4-0.40.30.3-0.91.01.11.1-1.2-1.3
Compulsive drug intake1.01.02.90.50.10.40.50.90.8-0.8-0.8-0.60.11.2-1.2-1.20.8-0.00.51.41.61.6-1.7-1.7
One hour access (shock baseline)0.10.21.1-0.3-0.60.30.30.40.4-0.4-0.4-0.30.60.1-0.1-0.10.41.0-0.60.1-0.1-0.10.30.1
Social response proportion1.61.82.6-0.5-0.91.01.21.51.5-1.5-1.4-1.30.91.5-1.3-1.51.51.40.31.61.61.6-1.4-1.6
Social responses1.41.82.8-1.1-1.11.51.51.21.2-1.2-1.1-1.70.71.6-1.6-1.61.60.60.71.51.51.5-1.5-1.4
Social time1.41.84.6-1.4-1.61.51.51.61.6-1.6-1.6-1.31.31.3-1.4-1.31.42.10.41.00.90.9-0.5-0.7
Soleus weight1.54.49.12.92.2-3.0-2.7-1.5-1.41.41.32.9-0.8-2.32.52.4-2.3-1.2-3.0-1.6-1.7-1.71.81.3
Bone: stiffness3.25.18.22.82.6-2.9-2.8-2.1-2.12.12.02.4-1.4-2.62.72.6-2.7-1.7-1.9-1.9-1.9-1.91.61.5
Tibialis anterior weight3.813.129.15.44.8-5.1-4.8-3.4-3.33.33.24.0-2.3-4.13.83.8-4.2-2.8-3.6-2.5-2.5-2.51.91.7
Time to tail flick, vehicle, before self-admin0.50.51.00.60.8-0.7-0.7-0.9-1.01.01.00.6-0.6-0.60.80.8-0.7-0.5-0.4-0.6-0.6-0.60.40.5
Time to tail flick, vehicle, after self-admin1.51.62.9-1.4-1.21.71.51.21.2-1.2-1.2-1.70.91.7-1.4-1.41.30.90.71.01.01.0-1.1-0.9
Time to tail flick, test, before self-admin1.11.11.70.20.8-0.8-1.0-1.1-1.11.11.11.0-0.9-1.01.21.2-1.1-0.90.8-1.3-1.2-1.21.01.2
Time to tail flick, test, after self-admin0.60.63.0-1.20.10.50.1-1.0-1.01.11.10.1-1.3-0.00.20.2-0.2-1.01.7-0.8-0.5-0.50.10.7
Delta time to tail flick, vehicle, before/after SA1.41.42.0-0.6-0.81.11.11.31.3-1.2-1.3-1.40.81.4-1.3-1.31.20.80.41.31.31.3-1.3-1.3
Delta time to tail flick, test, before/after SA0.20.20.4-0.4-0.00.40.3-0.2-0.30.30.3-0.3-0.40.4-0.4-0.40.4-0.50.60.30.40.4-0.6-0.4
Tibia length0.10.20.80.0-0.4-0.00.10.50.5-0.6-0.60.20.50.10.0-0.10.00.9-0.60.0-0.1-0.10.50.1
Ambulatory time before self-admin0.60.62.4-0.1-0.2-0.4-0.4-0.2-0.20.20.21.00.4-0.80.80.8-0.8-0.5-0.5-1.0-1.2-1.21.51.3
Ambulatory time after self-admin3.63.96.51.61.8-2.2-2.2-1.8-1.81.81.72.5-1.7-2.32.32.3-2.3-1.3-1.1-2.1-2.1-2.11.91.9
Bone: tissue strength0.30.30.70.10.3-0.4-0.5-0.5-0.50.50.50.8-0.5-0.60.70.6-0.5-0.5-0.0-0.7-0.7-0.70.60.7
Total heroin consumption2.83.35.0-1.0-1.51.81.91.81.8-1.8-1.7-2.21.42.0-2.0-2.02.11.9-0.32.12.02.0-1.8-1.9
Bone: trabecular number0.30.51.31.10.7-1.0-0.9-0.4-0.40.40.30.70.0-0.90.91.0-0.9-0.3-1.1-0.5-0.6-0.60.60.4
Bone: trabecular spacing1.01.34.6-1.1-0.41.11.10.40.4-0.4-0.3-1.0-0.31.4-1.5-1.51.3-0.22.11.01.31.3-1.5-1.2
Bone: trabecular thickness0.81.09.31.90.4-1.1-0.70.50.5-0.6-0.60.41.1-0.60.70.8-0.61.1-3.00.40.00.00.4-0.3
Bone: trabecular tissue density0.20.21.70.2-0.0-0.3-0.30.10.1-0.1-0.20.40.3-0.50.60.5-0.50.1-1.3-0.4-0.6-0.60.70.5
Water consumed over 24 hours2.02.44.6-0.90.4-0.3-0.7-1.8-1.81.81.81.4-2.1-1.21.21.2-1.2-1.80.7-2.1-2.0-2.01.72.1
Number of responses in last shaping day0.20.20.70.80.6-0.7-0.6-0.3-0.30.30.30.4-0.3-0.40.40.4-0.4-0.1-0.5-0.1-0.1-0.10.0-0.1