Hub : Genes

Syt17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA isoform ratio XM_017588770.3 0.04 0.03 3.9e-03 0.03 0.02 0.02 0.02 1.1e-03 1.3e-02 7.7e-03 5.6e-03
2 pVTA intron excision ratio chr1_182191400_182195689 0.05 0.03 6.6e-04 0.02 0.02 0.01 0.02 4.7e-03 4.5e-03 8.1e-02 1.7e-02
3 pVTA intron excision ratio chr1_182191405_182195689 0.05 0.03 3.5e-04 0.03 0.04 0.04 0.03 1.5e-03 7.5e-04 7.9e-04 1.5e-03
4 PL isoform ratio XM_006230104.2 0.04 0.03 8.8e-05 0.03 0.02 0.03 0.02 5.2e-04 9.9e-04 6.0e-04 3.3e-03
5 Liver gene expression Syt17 0.05 0.03 3.1e-05 0.02 0.02 0.02 0.01 1.5e-03 2.5e-03 2.8e-03 1.4e-02
6 PL intron excision ratio chr1_182191405_182191628 0.02 0.02 9.7e-03 0.01 0.01 0 0.01 4.3e-02 7.6e-03 1.3e-01 3.1e-02
7 Brain gene expression Syt17 0.2 0.09 8.9e-13 0.11 0.13 0.13 0.14 2.2e-10 1.8e-12 6.6e-12 7.1e-13
8 PL intron excision ratio chr1_182191400_182191628 0.03 0.02 3.2e-04 0.01 0.02 0.01 0.01 9.8e-03 1.8e-03 5.0e-02 1.4e-02
9 BLA isoform ratio XM_006230104.2 0.05 0.04 7.7e-03 -0 0.02 -0 0 5.1e-01 3.2e-02 4.6e-01 2.1e-01
10 IC mRNA stability Syt17 0.13 0.08 3.2e-04 0.07 0.07 0.06 0.07 4.8e-04 6.5e-04 1.0e-03 1.0e-03
11 Brain isoform ratio XM_006230104.2 0.04 0.02 2.3e-03 0.02 0.02 0.01 0.01 3.5e-03 7.7e-03 4.0e-02 1.9e-02
12 Adipose mRNA stability Syt17 0.05 0.03 2.1e-04 0.04 0.02 0.02 0.02 8.5e-05 2.7e-03 1.1e-03 1.1e-03
13 OFC mRNA stability Syt17 0.82 0.09 6.7e-16 0.41 0.37 0.32 0.33 7.2e-11 1.4e-09 3.1e-08 1.0e-08
14 Brain alternative TSS XM_017588772.2 0.04 0.03 4.2e-03 0.03 0.01 0.01 0.02 1.5e-03 1.3e-02 3.3e-02 9.1e-03
15 Brain alternative TSS XM_017588772.2 0.04 0.03 3.7e-03 0.03 0.01 0.01 0.02 8.9e-04 1.2e-02 5.5e-02 7.9e-03
16 NAcc gene expression Syt17 0.06 0.04 1.5e-08 0.06 0.05 0.06 0.06 1.7e-09 4.8e-08 5.2e-09 5.5e-09
17 LHb gene expression Syt17 0.18 0.11 4.5e-03 0.05 0.07 0.07 0.04 2.7e-02 1.1e-02 1.0e-02 3.7e-02
18 BLA alternative TSS XM_017588772.2 0.04 0.03 9.6e-03 0.03 0.01 0.02 0.01 1.2e-02 1.0e-01 2.8e-02 7.5e-02
19 pVTA gene expression Syt17 0.09 0.05 1.8e-06 0.08 0.06 0.07 0.07 6.0e-07 1.2e-05 2.8e-06 5.3e-06
20 BLA isoform ratio XM_017588770.3 0.06 0.04 5.5e-03 0.05 0.02 0.02 0.04 9.4e-04 2.4e-02 2.5e-02 2.4e-03
21 PL mRNA stability Syt17 0.1 0.05 4.2e-09 0.06 0.08 0.07 0.07 7.6e-07 7.8e-09 5.0e-08 6.8e-08
22 BLA gene expression Syt17 0.08 0.05 3.9e-03 0 0.02 0.03 0 3.1e-01 3.3e-02 8.5e-03 2.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.61.23.4-1.6-1.61.51.6-1.31.51.9-1.3-1.01.00.90.80.80.80.8-0.8-0.1-0.2-0.30.4-0.20.1
Area under the delay curve0.10.20.80.20.6-0.7-0.20.80.10.30.10.30.30.70.20.30.20.2-0.40.1-0.30.10.3-0.6-0.9
BMI with tail2.58.623.7-4.9-4.64.74.0-4.03.43.1-3.5-3.42.22.01.91.81.91.9-1.9-2.22.0-2.5-2.0-0.30.5
BMI without tail2.111.430.6-5.5-5.45.34.8-4.74.34.1-4.1-3.62.72.52.12.02.12.1-1.9-2.12.0-2.0-1.9-0.10.6
Body weight1.56.521.4-4.6-4.34.23.7-3.73.33.3-3.1-2.61.71.41.31.41.41.4-1.4-1.20.9-1.4-0.60.20.8
Weight adjusted by age0.20.63.20.0-0.70.90.2-1.4-0.7-0.80.3-0.2-0.7-1.1-0.7-0.8-0.7-0.70.70.10.5-0.50.11.11.8
Bone surface0.91.73.0-1.7-1.61.61.6-1.61.51.5-1.6-1.51.41.31.31.31.31.3-1.3-1.00.6-1.0-0.5-0.8-0.4
Bone volume1.22.44.9-2.2-2.01.92.1-1.92.02.1-1.9-1.71.71.71.41.41.41.4-1.4-0.90.6-0.9-0.2-0.7-0.3
Breakpoint value in progressive ratio session1.42.63.81.91.3-1.3-1.40.9-1.9-1.71.91.7-1.9-1.8-1.9-1.9-1.9-1.91.91.6-1.11.01.11.51.3
Number of licking bursts0.92.69.32.63.1-3.0-2.62.8-2.0-1.91.71.3-0.1-0.6-0.3-0.3-0.3-0.30.20.5-0.70.50.7-1.0-1.3
Context. condit. distance diff. score0.70.81.30.70.5-0.5-0.70.4-1.0-0.81.00.9-0.9-1.2-1.0-1.0-1.0-1.01.01.1-0.70.81.20.91.1
Locomotion velocity, session 10.30.30.90.20.3-0.30.10.30.40.3-0.4-0.30.50.70.80.90.80.8-0.8-0.3-0.40.50.1-0.9-0.9
Locomotion distance, session 10.30.41.6-0.8-1.21.11.2-1.30.70.7-0.6-0.4-0.3-0.20.10.10.10.1-0.00.3-0.1-0.00.80.50.8
Locomotion velocity, session 20.20.30.80.90.7-0.8-0.20.7-0.00.10.10.20.10.10.50.50.50.5-0.50.2-0.60.40.6-0.7-0.8
Locomotion distance, session 21.11.63.4-1.3-1.61.51.8-1.61.61.5-1.6-1.40.90.91.41.41.41.4-1.3-0.80.4-0.7-0.0-0.8-0.3
Locomotion velocity, session 30.10.10.4-0.2-0.60.50.7-0.60.40.2-0.4-0.40.00.10.30.40.30.3-0.3-0.20.5-0.3-0.1-0.10.1
Locomotion distance, session 30.70.82.7-0.2-0.20.40.3-0.50.3-0.0-0.7-1.10.80.91.01.11.01.0-1.0-1.31.6-1.3-1.2-1.0-0.6
Stereotopy head waving bouts, day 30.91.02.31.00.7-0.8-0.80.7-0.8-0.61.11.2-1.2-1.3-1.0-1.1-1.0-1.01.11.3-1.00.81.50.90.7
Stereotopy head waving duration, day 30.60.71.70.60.3-0.4-0.30.3-0.4-0.10.71.0-0.9-1.1-0.9-1.0-0.9-0.91.01.2-1.00.71.30.90.7
Locomotion velocity, session 71.21.32.8-0.6-0.91.11.1-1.30.70.2-1.2-1.61.11.11.21.31.21.2-1.1-1.71.4-1.3-1.4-1.0-0.4
Locomotion distance, session 70.40.51.60.20.2-0.1-0.0-0.10.10.1-0.5-0.91.00.81.01.01.01.0-0.9-1.10.0-0.4-0.9-1.2-1.0
Stereotopy head waving bouts, day 70.10.20.8-0.1-0.30.20.3-0.20.10.10.10.3-0.6-0.3-0.4-0.3-0.4-0.40.40.60.2-0.10.90.60.6
Stereotopy head waving duration, day 70.70.82.7-1.4-1.71.61.4-1.60.90.7-0.8-0.7-0.10.20.00.20.00.0-0.1-0.31.3-1.1-0.20.60.8
Locomotion velocity, session 80.10.10.40.60.1-0.20.10.10.10.00.00.2-0.2-0.20.10.10.10.1-0.10.4-0.70.50.7-0.1-0.0
Locomotion distance, session 80.10.22.1-0.0-0.40.40.5-0.60.20.3-0.1-0.1-0.1-0.40.20.20.20.2-0.10.6-0.40.01.50.10.7
Degree of sensitization distance0.70.74.70.30.3-0.5-0.20.5-0.10.40.50.9-0.5-0.6-0.6-0.7-0.6-0.60.71.3-2.21.71.40.60.3
Degree of sensitization stereotypy0.70.81.8-1.1-1.31.21.3-1.21.00.8-1.0-0.90.40.70.60.80.60.6-0.7-0.61.1-0.9-0.2-0.20.1
Conditioned locomotion0.30.31.20.91.0-0.7-1.00.5-1.1-1.10.70.2-0.3-0.3-0.4-0.2-0.3-0.30.2-0.3-0.0-0.0-0.5-0.3-0.1
Cocaine response after cond. corrected0.10.10.40.40.6-0.6-0.40.4-0.3-0.10.20.2-0.00.10.00.0-0.0-0.00.0-0.1-0.60.2-0.1-0.3-0.4
Cocaine response after cond. not corrected0.20.30.9-0.8-0.30.40.3-0.40.50.5-0.6-0.60.70.80.50.50.50.5-0.5-0.80.1-0.4-1.0-0.5-0.6
Cocaine response before conditioning2.53.15.8-2.4-1.81.91.7-1.71.81.4-2.0-2.11.91.91.61.61.51.5-1.6-1.91.9-1.8-1.9-1.1-0.8
Saline control response0.20.30.6-0.20.1-0.2-0.40.4-0.3-0.20.50.7-0.4-0.5-0.7-0.8-0.7-0.70.70.70.10.40.40.80.5
Bone: connectivity density0.40.61.8-1.1-1.31.31.1-1.30.90.9-0.9-0.90.50.50.40.30.40.4-0.4-0.50.2-0.6-0.60.10.3
Bone: cortical apparent density0.30.52.21.21.4-1.4-1.21.5-0.7-0.40.70.70.2-0.0-0.1-0.1-0.1-0.10.10.3-0.00.00.2-0.5-0.8
Bone: cortical area2.44.07.3-2.6-2.42.32.7-2.32.62.5-2.5-2.21.91.72.02.02.02.0-2.0-1.31.1-1.3-0.4-1.1-0.7
Bone: cortical porosity0.40.41.6-0.8-1.21.20.8-1.30.30.3-0.3-0.4-0.2-0.2-0.4-0.4-0.4-0.40.30.00.2-0.2-0.20.81.1
Bone: cortical porosity0.50.52.1-0.3-0.80.80.3-0.9-0.2-0.20.30.2-0.7-0.7-0.9-0.9-0.9-0.90.90.5-0.10.20.11.31.5
Bone: cortical thickness1.32.24.9-1.6-1.21.01.8-0.92.22.2-1.8-1.31.61.41.81.81.81.8-1.8-0.6-0.0-0.20.4-1.3-1.3
Bone: cortical thickness1.11.43.2-0.9-0.30.10.90.21.71.8-1.2-0.61.41.31.51.51.51.5-1.5-0.3-0.50.40.4-1.4-1.8
Bone: cortical tissue density0.30.52.21.21.4-1.4-1.21.5-0.7-0.50.70.70.1-0.1-0.2-0.2-0.2-0.20.10.3-0.00.00.2-0.4-0.7
Condit. Reinf. active minus inactive responses0.40.51.2-0.00.0-0.1-0.40.1-0.5-0.20.60.7-0.8-0.9-0.9-1.0-0.9-0.91.10.8-0.40.50.81.01.1
Condit. Reinf. active-inactive response ratio0.40.41.5-0.4-0.30.4-0.2-0.3-0.4-0.20.40.3-0.5-0.7-0.9-1.0-0.9-0.91.10.50.2-0.20.11.01.2
Condit. Reinf. active responses0.40.51.60.20.2-0.3-0.30.2-0.4-0.30.60.7-0.9-0.9-0.7-0.7-0.7-0.70.71.0-0.80.71.30.70.9
Condit. Reinf. inactive responses0.10.20.90.40.1-0.20.00.1-0.1-0.30.20.4-0.6-0.5-0.10.0-0.1-0.1-0.10.6-0.70.61.00.10.2
Incentive salience index mean0.10.10.4-0.4-0.30.40.0-0.5-0.2-0.1-0.0-0.3-0.0-0.2-0.1-0.2-0.1-0.10.3-0.20.6-0.6-0.30.20.6
Condit. Reinf. lever presses0.10.21.50.0-0.10.3-0.1-0.5-0.5-0.60.0-0.50.1-0.0-0.00.0-0.0-0.0-0.0-0.60.9-1.2-0.8-0.10.4
Condit. Reinf. active minus inactive responses0.71.03.7-0.6-1.31.20.8-1.10.20.40.10.3-0.9-1.0-1.0-1.1-0.9-0.91.21.10.4-0.81.01.71.9
Condit. Reinf. active-inactive response ratio0.71.03.4-0.3-0.60.50.1-0.4-0.3-0.10.60.8-1.3-1.2-1.4-1.4-1.3-1.31.51.2-0.10.00.71.91.7
Condit. Reinf. active responses0.50.72.3-0.6-1.21.20.7-1.10.20.2-0.1-0.0-0.5-0.8-0.7-0.7-0.6-0.60.70.61.3-1.50.51.21.5
Condit. Reinf. inactive responses0.91.45.9-0.8-1.01.11.0-1.10.80.6-1.2-1.41.20.81.01.01.11.1-1.1-1.12.3-2.4-0.8-0.8-0.3
Condit. Reinf. lever presses0.81.13.9-1.8-2.02.01.4-1.81.00.8-0.9-0.70.0-0.1-0.2-0.2-0.1-0.10.2-0.01.1-1.2-0.21.01.2
Condit. Reinf. lever reinforcers received0.60.82.9-0.3-0.90.90.4-0.9-0.1-0.10.30.3-0.8-1.1-1.0-1.1-0.9-0.91.00.90.8-1.00.71.51.7
Conditioned reinforcement - actives0.10.21.1-0.5-0.1-0.10.20.20.81.1-0.5-0.10.50.70.30.20.40.4-0.4-0.1-0.50.4-0.1-0.5-0.9
Conditioned reinforcement - inactives0.20.41.70.71.1-1.2-0.81.3-0.10.00.20.40.30.30.30.10.30.3-0.30.1-0.60.50.2-0.9-1.2
Conditioned locomotion0.10.10.40.50.5-0.5-0.20.3-0.00.10.00.10.30.40.20.10.20.2-0.2-0.2-0.10.1-0.3-0.4-0.7
Patch foraging indifference point 0 sec0.20.71.9-0.7-0.90.70.7-0.90.50.70.00.6-0.7-0.6-0.9-0.9-0.7-0.70.81.3-0.00.01.21.41.1
Patch foraging indifference point AUC0.30.81.7-0.8-0.90.71.0-0.81.31.2-1.1-0.81.00.81.00.91.11.1-1.0-0.50.3-0.7-0.2-0.7-0.7
Delay disc. indifference point, 0s delay2.73.15.0-1.0-0.50.51.3-0.61.61.6-1.7-1.72.22.22.12.22.12.1-2.2-1.81.3-2.2-1.3-2.1-2.0
Delay disc. indifference point, 16s delay2.84.06.42.22.3-2.5-2.32.4-2.0-1.52.32.5-1.8-1.6-1.8-1.8-1.8-1.81.92.2-2.12.02.11.00.5
Delay disc. indifference point, 2s delay4.34.87.0-2.4-2.22.12.6-1.92.52.3-2.6-2.52.32.42.22.42.22.2-2.5-2.21.5-2.0-1.7-1.6-1.3
Delay disc. indifference point, 24s delay1.52.45.92.22.4-2.4-2.32.4-1.9-1.61.91.9-1.3-1.1-1.3-1.2-1.3-1.31.11.2-0.30.51.00.3-0.2
Delay disc. indifference point, 4s delay0.60.71.9-0.30.2-0.40.50.30.91.2-0.6-0.21.01.40.91.10.90.9-1.2-0.20.0-0.30.4-1.1-1.4
Delay disc. indifference point, 8s delay0.30.51.7-0.50.2-0.20.20.30.50.6-0.5-0.40.91.30.80.80.80.8-0.9-0.50.4-0.2-0.3-1.0-1.2
Indifference point function ln k0.00.10.2-0.4-0.40.30.5-0.20.30.5-0.3-0.20.10.30.30.40.10.1-0.3-0.1-0.40.40.1-0.1-0.0
Indifference point function log k0.00.10.2-0.4-0.40.30.5-0.20.30.5-0.3-0.20.10.30.30.40.10.1-0.3-0.1-0.40.40.1-0.1-0.0
Patch foraging total patch changes 0 sec0.30.92.6-0.8-1.10.90.7-1.00.60.70.00.6-0.8-0.7-1.0-1.0-0.9-0.91.01.4-0.20.21.31.61.3
Patch foraging total patch changes 12 sec0.20.21.0-0.1-0.70.60.4-1.00.30.1-0.1-0.1-0.3-0.6-0.3-0.4-0.1-0.10.30.40.3-0.60.30.60.8
Patch foraging total patch changes 18 sec0.00.00.2-0.1-0.0-0.10.0-0.10.40.2-0.10.20.10.2-0.0-0.10.10.10.10.30.4-0.30.10.1-0.3
Patch foraging total patch changes 24 sec0.10.41.3-1.0-1.10.90.8-0.71.01.1-0.6-0.10.2-0.1-0.1-0.30.00.00.10.70.2-0.30.70.60.4
Patch foraging total patch changes 6 sec0.81.45.60.50.2-0.6-0.30.70.10.40.81.7-1.1-1.1-1.3-1.3-1.1-1.11.22.3-0.90.92.41.50.7
Patch foraging time to switch 0 sec0.52.06.72.32.1-1.8-2.11.1-2.4-2.61.81.0-1.1-1.2-1.0-1.3-1.0-1.01.10.30.5-0.3-0.20.10.4
Patch foraging water rate 0 sec0.10.20.9-0.7-0.90.80.7-1.00.60.7-0.5-0.30.30.10.10.40.10.1-0.3-0.1-0.1-0.00.30.20.3
Patch foraging water rate 12 sec0.20.84.0-2.0-1.61.31.3-0.91.61.7-1.0-0.30.30.50.10.20.00.0-0.10.2-0.60.40.30.60.2
Patch foraging water rate 18 sec0.30.61.9-0.4-0.90.70.6-0.60.30.60.00.4-0.8-0.7-0.7-0.4-0.8-0.80.50.8-1.31.41.01.11.1
Patch foraging water rate 24 sec0.50.72.4-0.7-0.70.51.1-0.31.31.6-1.0-0.61.10.81.01.20.80.8-1.0-0.40.20.00.2-0.7-0.7
Patch foraging water rate 6 sec0.20.31.2-0.4-0.0-0.20.20.80.70.8-0.30.20.30.30.30.30.20.2-0.40.4-1.10.70.8-0.2-0.7
Seeking ratio, delayed vs. immediate footshock0.00.00.10.0-0.10.10.2-0.10.20.1-0.1-0.10.20.20.10.00.10.10.2-0.20.40.2-0.20.1-0.1
Distance traveled before self-admin0.30.71.4-0.2-0.10.00.40.10.90.9-0.8-0.51.11.11.01.11.01.0-0.9-0.60.9-0.8-0.2-1.0-1.2
Distance traveled after self-admin2.34.06.3-1.6-1.21.21.6-1.12.11.9-2.2-2.22.42.52.42.52.42.4-2.5-2.31.1-1.2-1.9-2.1-2.0
Extensor digitorum longus weight5.220.629.4-5.1-4.34.54.7-4.14.64.3-5.2-5.45.04.94.64.54.74.7-4.5-4.74.6-4.6-4.1-3.3-2.5
Bone: elastic displacement0.60.82.11.30.9-1.0-0.81.1-0.5-0.20.81.2-0.7-0.6-0.7-0.8-0.7-0.70.81.2-1.41.40.90.5-0.1
Bone: elastic work0.30.41.1-0.5-0.60.50.8-0.50.91.1-0.8-0.50.80.90.60.50.60.6-0.5-0.2-0.1-0.1-0.1-0.4-0.6
Bone: endosteal estimation1.23.06.2-2.2-2.32.52.0-2.41.51.4-1.9-2.21.51.41.21.21.21.2-1.2-1.72.1-2.1-1.6-0.50.3
Bone: endosteal perimeter0.92.34.9-1.5-1.51.71.5-1.91.00.8-1.6-2.01.41.31.41.41.41.4-1.4-1.72.1-2.2-1.3-1.0-0.2
Epididymis fat weight0.31.65.7-2.3-2.42.32.1-1.71.61.7-1.4-1.00.50.10.40.30.40.4-0.3-0.0-0.0-0.20.30.61.0
Delta time in closed arm before/after self-admin0.90.93.1-0.2-0.30.60.5-0.80.1-0.2-0.7-1.20.90.80.90.70.90.9-0.9-1.51.5-1.6-1.8-0.9-0.5
Delta time in open arm before/after self-admin0.80.92.7-1.5-1.61.51.5-1.41.41.5-1.2-0.90.60.50.60.60.60.6-0.7-0.10.0-0.10.40.10.4
Diff in mean of infusions in LGA sessions0.81.54.60.70.3-0.5-0.30.7-0.5-0.10.91.3-1.2-1.2-1.2-1.2-1.2-1.21.11.8-2.11.92.01.21.0
Delay discount exponential model param0.10.20.7-0.3-0.70.80.3-0.90.0-0.2-0.1-0.3-0.3-0.6-0.2-0.3-0.2-0.20.3-0.10.2-0.1-0.30.60.8
Extinction: sum of active levers before priming0.30.51.20.90.7-0.6-0.80.4-1.1-1.10.90.6-0.8-0.9-0.8-0.8-0.8-0.80.70.4-0.2-0.10.10.50.6
Active lever presses in extinction session 60.30.30.6-0.1-0.20.20.1-0.4-0.2-0.20.30.3-0.7-0.7-0.7-0.6-0.7-0.70.50.5-0.80.50.40.80.7
Bone: final force3.86.111.1-3.0-3.13.03.3-2.93.13.0-3.1-2.82.52.22.42.52.42.4-2.4-1.81.6-1.7-0.9-1.3-0.8
Bone: final moment3.04.89.7-2.7-2.92.83.1-2.72.92.8-2.8-2.42.11.82.02.12.02.0-2.0-1.41.2-1.3-0.6-1.0-0.5
Food consumed during 24 hour testing period1.02.13.1-1.7-1.51.41.7-1.41.71.4-1.8-1.71.61.61.61.61.61.6-1.7-1.30.7-0.7-0.7-1.1-0.7
Glucose0.10.20.70.70.3-0.4-0.20.3-0.1-0.40.30.5-0.5-0.8-0.1-0.1-0.1-0.10.10.6-0.50.90.70.20.2
Heart weight0.10.10.40.0-0.30.20.5-0.30.30.3-0.2-0.1-0.10.00.30.20.30.3-0.30.2-0.60.60.5-0.20.0
Delay discount hyperbolic model param0.10.20.60.1-0.30.4-0.1-0.4-0.3-0.50.20.0-0.5-0.8-0.4-0.5-0.4-0.40.50.1-0.00.2-0.10.60.8
Intermittent access intake day 1-15 change0.21.03.61.01.3-1.3-0.91.3-0.1-0.1-0.1-0.21.11.01.01.10.80.8-0.8-1.00.5-0.3-0.9-1.7-1.9
Intermittent access intake escalation0.21.03.61.31.5-1.5-1.01.4-0.2-0.00.10.00.90.80.91.00.70.7-0.7-0.80.2-0.1-0.6-1.6-1.9
Intermittent access intake escalation 20.71.24.41.51.6-1.6-1.01.4-0.2-0.00.0-0.11.21.11.21.10.80.8-0.8-0.90.3-0.3-0.8-1.9-2.1
Intermitt. access day 1 inactive lever presses0.00.31.00.50.8-0.8-0.60.6-0.1-0.20.1-0.00.60.50.50.30.40.4-0.4-0.30.40.1-0.4-0.8-1.0
Intermitt. access day 15 inactive lever presses0.10.51.1-0.7-0.50.50.6-0.50.60.5-0.8-0.91.00.51.00.80.80.8-0.8-0.70.6-0.3-0.3-0.8-0.4
Intermitt. access escalation Index0.00.10.5-0.6-0.70.70.5-0.60.30.3-0.3-0.3-0.10.3-0.00.1-0.2-0.20.2-0.3-0.10.0-0.50.30.3
Intermittent access day 1 total infusions0.10.41.3-1.0-1.11.11.0-1.10.60.5-0.5-0.40.0-0.2-0.1-0.2-0.0-0.00.00.20.10.40.20.60.8
Intermittent access day 15 total infusions0.00.10.40.20.3-0.3-0.00.30.20.3-0.2-0.10.60.30.40.40.40.4-0.4-0.30.20.4-0.1-0.6-0.6
Intermittent access terminal intake (last 3 days)0.10.10.3-0.1-0.20.20.4-0.20.40.5-0.4-0.30.50.30.30.30.30.3-0.3-0.20.20.3-0.0-0.3-0.3
Intermittent access total infusions0.50.61.5-1.1-1.11.01.2-1.01.21.2-1.0-0.70.70.50.50.50.60.6-0.6-0.40.30.2-0.2-0.2-0.1
Intermittent access day 1 locomotion0.10.20.6-0.7-0.80.70.7-0.70.50.5-0.3-0.0-0.2-0.5-0.2-0.3-0.1-0.10.10.5-0.20.50.70.60.6
Intermittent access day 15 total locomotion0.10.42.1-0.10.2-0.3-0.30.4-0.00.10.40.7-0.5-0.5-0.6-0.8-0.7-0.70.70.8-0.61.50.70.50.1
Intermittent access total locomotion0.30.41.1-0.6-0.70.60.6-0.50.40.6-0.10.2-0.3-0.7-0.5-0.6-0.4-0.40.40.8-0.51.00.80.80.8
Intermittent access standard deviation0.63.36.2-0.5-0.70.71.3-0.81.71.7-1.9-1.92.52.02.32.32.32.3-2.3-1.91.7-1.4-1.3-2.3-1.9
Left kidney weight1.08.016.1-4.0-3.63.53.6-3.33.63.8-3.5-3.13.02.72.52.52.42.4-2.5-2.11.6-2.0-1.2-1.2-0.8
Right kidney weight1.28.220.2-4.5-4.14.04.0-3.53.84.0-3.6-3.12.62.52.22.22.22.2-2.3-1.81.3-1.6-1.1-0.7-0.4
Cocaine induced anxiety0.00.10.20.50.5-0.4-0.50.4-0.4-0.40.2-0.00.1-0.20.10.20.30.3-0.3-0.20.3-0.4-0.1-0.4-0.2
Post-drug Anxiety0.60.72.01.20.9-1.0-0.80.9-0.6-0.20.81.1-0.7-1.0-0.7-0.6-0.6-0.60.61.2-1.21.11.40.30.2
Baseline Anxiety0.20.31.60.1-0.1-0.20.30.10.61.0-0.00.5-0.10.1-0.1-0.2-0.2-0.20.20.9-1.31.21.10.2-0.1
Tail length0.31.54.4-2.0-1.71.41.7-1.32.02.1-1.5-0.91.11.10.91.10.90.9-0.9-0.4-0.10.20.2-0.2-0.4
Length with tail0.10.42.5-0.8-0.60.40.5-0.40.60.8-0.20.3-0.2-0.5-0.2-0.1-0.1-0.10.10.9-1.10.91.60.50.5
Length without tail0.31.64.41.31.3-1.4-1.31.3-1.1-1.01.31.5-1.3-1.6-1.0-0.8-0.9-0.90.71.5-1.71.22.10.50.4
Times rat made contact with spout2.93.45.3-1.3-0.91.11.4-1.11.51.1-1.9-2.22.22.02.22.32.22.2-2.3-2.21.7-1.7-1.6-2.2-1.6
Lifetime Intake0.70.92.1-1.4-1.41.31.4-1.31.41.3-1.2-0.90.80.70.60.50.70.7-0.7-0.50.40.1-0.3-0.2-0.1
Liver weight, left0.81.43.1-0.3-0.00.2-0.8-0.5-1.2-1.51.10.8-1.5-1.2-1.7-1.7-1.6-1.61.70.5-0.10.4-0.51.81.7
Liver weight, right0.40.81.8-0.2-0.10.3-0.5-0.4-1.0-1.20.70.3-1.0-0.8-1.2-1.2-1.2-1.21.2-0.00.7-0.4-0.81.21.3
Locomotor activity0.20.30.9-0.7-0.50.5-0.0-0.1-0.1-0.20.10.1-0.4-0.4-0.7-0.4-0.6-0.60.50.21.0-0.9-0.00.80.8
Locomotor testing distance0.10.20.5-0.7-0.70.70.4-0.40.30.2-0.2-0.1-0.0-0.1-0.3-0.1-0.2-0.20.20.10.5-0.40.10.50.6
Locomotor testing rearing0.20.82.4-0.0-0.20.3-0.30.2-0.6-0.70.70.7-1.1-1.2-1.2-1.1-1.2-1.21.10.90.1-0.10.71.41.5
Locomotion in novel chamber0.50.72.3-0.7-1.11.00.8-0.80.20.20.10.3-1.0-0.8-1.0-0.9-1.0-1.00.90.7-0.40.20.31.51.4
Locomotion in novel chamber post-restriction0.61.94.20.70.2-0.3-0.60.5-0.8-0.61.21.5-1.6-2.0-1.6-1.4-1.6-1.61.61.9-1.41.22.11.81.7
Fecal boli incidents, locomotor time 10.41.03.11.00.5-0.3-1.00.4-1.5-1.81.20.7-1.3-1.2-1.2-1.0-1.1-1.11.20.2-0.4-0.1-0.21.11.3
Change in fecal boli incidents, locomotor task0.50.52.2-0.6-0.70.41.1-0.11.01.5-0.30.5-0.1-0.1-0.2-0.3-0.4-0.4-0.11.3-0.41.11.50.50.2
Time >=10cm from walls, locomotor time 10.30.41.0-0.1-0.40.30.6-0.60.60.6-0.7-0.70.80.40.91.00.70.7-0.7-0.50.2-0.10.1-0.8-0.5
Bouts of movement, locomotor time 12.12.75.02.02.0-1.9-2.21.3-2.2-2.22.11.8-1.6-1.4-1.7-1.8-1.7-1.71.81.3-0.20.90.41.00.6
Total resting periods, locomotor time 12.63.05.82.12.1-2.0-2.31.5-2.4-2.42.31.9-1.7-1.4-1.9-1.9-1.9-1.91.91.2-0.20.70.31.10.6
Rest time, locomotor task time 10.50.72.51.61.6-1.5-1.31.0-1.2-1.31.00.7-0.3-0.6-0.3-0.3-0.3-0.30.20.20.5-0.5-0.0-0.5-0.6
Distance moved, locomotor task time 10.30.82.9-1.7-1.71.51.4-1.21.31.4-1.0-0.70.30.40.30.20.30.3-0.2-0.0-0.1-0.10.00.50.6
Vertical activity count, locomotor time 10.42.75.9-1.7-1.61.42.0-1.22.32.4-2.1-1.71.92.01.91.71.81.8-1.7-1.10.4-0.1-0.7-1.2-1.2
Time >=10cm from walls, locomotor time 20.71.93.0-1.4-1.21.21.3-1.31.61.5-1.7-1.61.61.41.71.71.51.5-1.3-1.31.0-0.7-0.7-1.3-0.9
Bouts of movement, locomotor time 20.20.74.50.0-0.71.10.4-1.2-0.6-1.10.0-0.7-0.3-0.4-0.3-0.3-0.1-0.10.2-0.81.2-2.1-1.30.71.3
Total resting periods, locomotor time 20.20.85.3-0.2-0.91.20.6-1.3-0.4-0.9-0.2-0.9-0.1-0.3-0.1-0.10.10.10.1-0.91.4-2.3-1.40.61.1
Rest time, locomotor task time 20.00.10.70.40.1-0.2-0.00.1-0.00.20.20.3-0.1-0.3-0.1-0.10.00.00.10.5-0.4-0.20.90.10.1
Distance moved, locomotor task time 21.62.13.9-1.1-0.40.40.7-0.41.31.2-1.5-1.51.92.01.91.61.71.7-1.5-1.51.4-1.5-1.3-1.7-1.8
Vertical activity count, locomotor time 20.71.73.5-0.6-0.20.00.7-0.11.51.6-1.4-1.11.81.71.91.51.81.8-1.4-0.80.8-0.4-0.3-1.8-1.9
Light reinforcement 10.41.95.01.60.3-0.4-0.6-0.1-1.1-1.31.21.3-1.9-2.2-1.7-1.7-1.4-1.41.51.5-1.71.11.01.61.6
Light reinforcement 20.40.92.30.4-0.20.1-0.2-0.3-0.5-0.30.70.8-1.0-1.2-1.2-1.2-1.1-1.11.11.1-1.51.30.71.31.2
Bone: marrow area1.12.75.5-2.1-2.22.31.9-2.31.41.3-1.8-2.11.41.31.11.21.11.1-1.1-1.72.0-2.1-1.5-0.40.2
Bone: maximum diameter1.63.36.4-2.4-2.52.52.5-2.52.01.8-2.2-2.21.51.31.51.51.51.5-1.5-1.41.6-1.6-0.9-0.6-0.0
Bone: maximum force3.05.910.0-2.9-2.92.83.2-2.73.02.9-3.0-2.72.52.32.42.52.42.4-2.4-1.81.7-1.8-0.9-1.4-0.9
Bone: maximum moment2.44.48.4-2.7-2.72.62.9-2.52.72.7-2.7-2.32.12.02.02.02.02.0-1.9-1.41.3-1.3-0.6-1.0-0.6
Mean time between licks in bursts0.10.31.41.00.5-0.4-0.60.1-0.9-1.20.60.3-0.6-0.6-0.5-0.6-0.5-0.50.50.10.4-0.2-0.20.30.5
Mean num. licks in bursts1.95.010.7-3.2-3.33.23.2-3.12.82.5-2.8-2.51.61.91.71.71.71.7-1.7-1.81.5-1.2-1.6-0.5-0.1
Cd content in liver4.34.89.31.30.3-0.6-1.00.7-1.4-1.42.02.4-2.9-2.7-2.8-2.8-2.8-2.82.82.6-2.12.01.83.12.5
Co content in liver0.50.62.0-0.00.3-0.60.10.90.91.3-0.30.30.60.60.60.50.60.6-0.50.6-1.41.31.0-0.7-1.2
Cu content in liver0.50.62.1-1.3-1.21.11.1-0.71.31.4-0.9-0.50.70.40.30.20.30.3-0.2-0.00.3-0.5-0.00.2-0.0
Fe content in liver0.20.21.00.20.5-0.7-0.41.00.10.50.30.60.20.1-0.2-0.2-0.2-0.20.20.6-0.10.30.6-0.0-0.6
K content in liver0.10.10.4-0.3-0.60.60.5-0.60.30.2-0.2-0.20.1-0.0-0.0-0.1-0.0-0.00.00.00.3-0.1-0.10.30.5
Mg content in liver0.20.20.8-0.1-0.50.60.2-0.7-0.2-0.20.0-0.2-0.1-0.3-0.3-0.4-0.3-0.30.4-0.00.6-0.9-0.30.50.8
Mn content in liver0.60.72.1-1.1-0.80.90.8-0.90.60.5-0.8-1.00.90.90.60.50.60.6-0.6-1.01.4-1.0-1.2-0.4-0.2
Na content in liver3.33.87.4-1.7-2.12.32.2-2.71.60.9-2.2-2.71.81.52.02.02.02.0-2.0-2.41.7-1.4-2.1-1.3-0.4
Rb content in liver3.94.610.31.30.9-1.4-1.31.7-1.0-0.72.12.9-2.4-2.3-2.5-2.6-2.5-2.52.53.2-2.11.82.92.61.6
Se content in liver0.40.50.9-0.6-0.20.30.4-0.40.50.4-0.7-0.80.91.00.80.80.80.8-0.8-0.90.7-0.6-0.8-0.9-0.8
Sr content in liver0.90.72.3-1.0-1.01.10.9-0.90.60.2-0.9-1.10.70.70.60.60.60.6-0.6-1.21.5-0.8-1.5-0.2-0.0
Zn content in liver0.91.14.7-1.4-1.92.01.4-2.20.80.8-1.0-1.10.10.00.20.00.20.2-0.0-0.50.4-1.1-0.70.61.2
Bone: minimum diameter1.52.95.5-1.9-2.22.32.2-2.31.71.6-2.0-2.21.51.31.51.51.51.5-1.5-1.51.8-2.0-1.0-0.8-0.1
Time in familiar zone, hab. session 10.30.41.50.20.7-0.9-0.51.20.00.00.40.8-0.1-0.1-0.2-0.2-0.2-0.20.00.7-0.91.20.70.1-0.5
Time in novel zone, hab. session 10.30.31.7-0.1-0.80.90.6-1.3-0.1-0.1-0.3-0.7-0.2-0.2-0.00.1-0.0-0.00.1-0.50.6-0.9-0.50.10.7
Total zone transitions, hab. session 11.42.04.8-1.7-1.91.72.2-1.62.12.1-1.8-1.21.01.11.41.51.41.4-1.4-0.40.1-0.30.8-0.6-0.2
Total locomotion distance, hab. session 12.94.111.0-3.0-3.12.83.3-2.72.93.2-2.5-1.81.41.61.61.51.61.6-1.4-0.30.5-0.80.9-0.20.3
Locomotion velocity, hab. session 12.13.08.8-2.5-2.92.63.0-2.52.52.7-2.0-1.40.91.11.11.01.11.1-0.9-0.00.4-0.71.00.20.7
Time in familiar zone, hab. session 20.30.30.6-0.6-0.60.60.7-0.50.80.6-0.7-0.50.40.40.60.50.60.6-0.7-0.40.1-0.1-0.4-0.3-0.3
Time in novel zone, hab. session 20.20.20.40.00.1-0.0-0.30.1-0.4-0.30.40.4-0.5-0.4-0.6-0.5-0.6-0.60.70.3-0.20.30.20.60.5
Total zone transitions, hab. session 21.01.33.6-1.6-1.91.71.9-1.51.71.7-1.4-0.90.50.40.81.00.80.8-0.9-0.0-0.0-0.21.00.00.4
Total locomotion distance, hab. session 21.82.35.8-1.9-2.21.92.4-1.72.32.3-1.9-1.31.11.21.41.41.41.4-1.4-0.30.1-0.20.9-0.5-0.1
Locomotion velocity, hab. session 22.02.76.8-2.1-2.42.22.6-2.02.42.4-2.1-1.61.31.21.61.61.61.6-1.5-0.50.3-0.40.8-0.50.0
Novel to familiar place preference ratio0.30.41.30.61.0-1.1-0.81.1-0.5-0.10.60.7-0.1-0.1-0.1-0.1-0.1-0.10.20.7-1.10.81.1-0.3-0.4
Novelty place preference0.40.51.60.81.2-1.3-0.91.2-0.4-0.10.50.60.00.10.20.10.20.2-0.00.6-1.10.81.1-0.6-0.7
Time in novel zone, NPP test0.40.51.70.71.0-1.1-0.81.1-0.4-0.10.60.8-0.2-0.2-0.1-0.2-0.1-0.10.20.9-1.31.01.3-0.2-0.4
Total zone transitions, NPP test0.81.23.0-1.4-1.51.41.7-1.41.61.5-1.4-1.10.80.81.01.11.01.0-1.0-0.50.4-0.40.1-0.4-0.1
Total locomotion distance, NPP test1.31.84.2-1.5-1.51.31.9-1.21.92.0-1.7-1.21.31.41.51.41.51.5-1.4-0.50.4-0.70.3-0.9-0.6
Locomotion velocity, NPP test1.11.63.6-1.4-1.31.11.8-1.11.81.9-1.6-1.21.31.41.51.41.51.5-1.4-0.60.4-0.60.2-0.9-0.7
Intraocular pressure0.10.20.8-0.6-0.70.70.4-0.90.30.6-0.4-0.50.30.20.20.00.00.0-0.0-0.3-0.1-0.5-0.30.00.2
Delta distance traveled before/after self-admin0.50.51.2-1.1-0.91.00.9-1.10.60.5-0.8-0.90.40.50.50.60.50.5-0.8-0.9-0.2-0.2-0.9-0.3-0.0
Delta ambulatory time before/after self-admin0.71.32.0-1.4-1.11.21.2-1.21.10.9-1.3-1.41.01.11.11.11.11.1-1.3-1.40.1-0.4-1.4-0.8-0.5
Parametrial fat weight1.12.69.0-2.9-3.02.72.5-2.22.12.2-1.3-0.5-0.1-0.3-0.4-0.3-0.3-0.30.20.7-0.91.00.91.81.7
Pavlov. Cond. lever latency0.70.93.50.30.8-1.3-0.31.70.71.10.11.10.20.20.30.30.30.3-0.31.4-1.41.31.9-0.4-1.2
Pavlov. Cond. magazine entry latency2.02.69.9-1.8-2.42.81.7-3.20.5-0.1-1.3-2.10.40.20.30.10.30.3-0.1-1.92.0-1.7-2.50.51.6
Pavlov. Cond. change in total contacts1.61.77.0-0.7-0.91.40.6-1.8-0.2-0.8-0.8-1.90.80.70.70.70.70.7-0.7-2.32.4-2.2-2.6-0.60.4
Pavlov. Cond. index score1.31.76.3-1.0-1.52.00.8-2.3-0.3-0.9-0.6-1.50.1-0.1-0.2-0.2-0.2-0.20.2-1.82.1-1.8-2.50.61.5
Pavlov. Cond. latency score1.11.45.0-1.0-1.51.90.8-2.2-0.2-0.7-0.6-1.40.1-0.1-0.2-0.2-0.2-0.20.2-1.61.8-1.7-2.20.61.4
Pavlov. Cond. lever contacts1.31.55.7-1.0-1.52.00.9-2.4-0.2-0.6-0.7-1.60.10.10.00.00.00.0-0.0-1.71.9-1.7-2.20.41.3
Pavlov. Cond. magazine entry number1.31.76.21.11.5-1.9-1.02.3-0.00.60.91.8-0.5-0.2-0.3-0.2-0.3-0.30.21.9-2.01.92.5-0.1-1.0
Pavlov. Cond. intertrial magazine entries1.61.95.80.91.1-1.4-1.01.5-0.5-0.11.21.8-1.2-1.0-1.1-1.0-1.1-1.10.92.1-2.32.12.40.90.2
Pavlov. Cond. lever-magazine prob. diff.1.51.97.0-1.2-1.72.21.0-2.6-0.2-0.8-0.7-1.70.2-0.0-0.1-0.1-0.1-0.10.1-1.92.1-1.8-2.60.61.6
Pavlov. Cond. response bias1.51.97.5-0.9-1.52.00.9-2.4-0.2-0.8-0.9-1.90.50.30.40.30.40.4-0.3-2.22.3-2.0-2.7-0.01.1
Pavlov. Cond. lever latency0.60.83.41.81.7-1.7-1.31.6-1.0-0.80.80.70.10.2-0.1-0.10.00.00.10.10.00.1-0.1-0.7-0.9
Pavlov. Cond. magazine entry latency0.30.51.80.70.9-0.7-1.10.5-1.2-1.30.80.4-0.5-0.4-0.5-0.6-0.6-0.60.6-0.20.3-0.6-0.70.10.0
Pavlov. Cond. change in total contacts0.51.33.7-0.5-0.50.30.1-0.2-0.10.20.61.1-1.3-1.4-1.2-1.3-1.3-1.31.21.8-1.31.01.91.71.6
Pavlov. Cond. index score0.20.20.7-0.6-0.40.50.0-0.5-0.2-0.30.20.2-0.6-0.6-0.5-0.6-0.7-0.70.50.3-0.1-0.20.10.80.8
Pavlov. Cond. latency score0.10.10.4-0.6-0.40.50.1-0.5-0.1-0.30.0-0.1-0.3-0.3-0.3-0.3-0.4-0.40.3-0.00.1-0.3-0.20.50.5
Pavlov. Cond. lever contacts0.50.83.3-1.8-1.71.71.2-1.70.80.6-0.7-0.6-0.2-0.3-0.0-0.0-0.1-0.1-0.0-0.10.1-0.30.10.71.0
Pavlov. Cond. magazine entry number1.11.52.9-1.2-1.41.31.7-1.21.61.5-1.5-1.31.21.21.21.31.31.3-1.3-0.90.4-0.2-0.4-0.7-0.5
Pavlov. Cond. intertrial magazine entries0.91.95.4-1.8-2.32.32.0-2.21.51.3-1.6-1.60.80.60.60.70.80.8-0.7-1.01.6-1.4-1.00.20.7
Pavlov. Cond. lever-magazine prob. diff.0.20.20.6-0.4-0.20.3-0.2-0.3-0.4-0.50.30.2-0.7-0.6-0.6-0.7-0.7-0.70.60.20.1-0.4-0.00.70.8
Pavlov. Cond. response bias0.30.41.2-0.9-0.80.80.3-0.8-0.0-0.10.10.1-0.7-0.7-0.5-0.7-0.7-0.70.60.4-0.0-0.30.21.01.1
Time in closed arm before self-admin0.00.00.1-0.3-0.20.20.2-0.10.30.2-0.2-0.10.10.10.20.20.20.2-0.10.0-0.20.20.3-0.10.0
Time in closed arm after self-admin0.10.10.40.40.6-0.7-0.30.7-0.10.00.30.5-0.1-0.0-0.1-0.2-0.1-0.10.10.3-0.40.30.2-0.1-0.5
Time in open arm before self-admin0.60.81.71.31.2-1.2-1.31.0-1.2-1.21.10.8-0.7-0.8-0.7-0.7-0.7-0.70.90.3-0.40.6-0.20.30.0
Time in open arm after self-admin2.32.54.0-1.5-1.51.61.5-1.51.51.2-1.8-2.01.81.51.71.81.71.7-1.7-1.91.4-1.3-1.5-1.3-0.7
Bone: periosteal estimation2.56.09.8-3.1-3.13.13.1-3.12.72.5-2.9-3.02.32.12.22.22.22.2-2.2-2.12.2-2.4-1.4-1.2-0.4
Bone: periosteal perimeter1.02.06.0-1.8-2.22.22.0-2.41.41.2-1.6-1.81.00.70.91.00.90.9-0.9-1.01.4-1.5-0.6-0.20.5
Bone: post-yield work1.22.07.3-2.5-2.72.72.1-2.41.41.2-1.3-1.10.10.3-0.10.0-0.1-0.1-0.0-0.41.1-0.5-0.61.21.7
Progressive ratio test 1 active lever presses0.10.20.9-0.7-0.80.80.6-0.90.2-0.0-0.3-0.50.20.10.0-0.10.10.1-0.1-0.21.0-0.4-0.30.40.5
Progressive ratio test 1 breakpoint0.10.20.9-0.6-0.70.80.5-0.80.1-0.1-0.3-0.40.20.1-0.0-0.10.10.1-0.1-0.20.9-0.4-0.30.40.5
Progressive ratio test 1 inactive lever presses0.00.10.4-0.4-0.20.30.1-0.5-0.2-0.6-0.0-0.2-0.0-0.1-0.0-0.10.10.1-0.1-0.20.4-0.1-0.40.20.3
Progressive ratio test 2 active lever presses0.10.10.5-0.3-0.20.20.0-0.1-0.3-0.60.30.2-0.4-0.3-0.5-0.6-0.4-0.40.40.30.00.40.00.70.6
Progressive ratio test 2 breakpoint0.20.20.6-0.3-0.10.2-0.0-0.1-0.4-0.60.40.3-0.5-0.5-0.6-0.7-0.5-0.50.50.4-0.10.50.20.80.7
Progressive ratio test 2 inactive lever presses0.10.20.9-0.9-0.70.80.6-0.60.40.2-0.4-0.40.30.10.2-0.00.10.1-0.1-0.20.20.2-0.20.20.3
Incentive Sensitization - Responses0.00.10.5-0.20.10.0-0.20.2-0.4-0.70.30.1-0.3-0.1-0.3-0.3-0.3-0.30.3-0.00.10.2-0.30.40.3
Incentive Sensitization - Breakpoint0.00.10.4-0.3-0.00.1-0.10.1-0.4-0.60.30.2-0.4-0.2-0.4-0.4-0.4-0.40.40.10.00.3-0.20.50.5
Sum of active levers in priming session hrs 5-63.12.95.51.20.5-0.4-1.00.2-2.0-2.01.81.4-2.2-2.2-2.2-2.2-2.2-2.22.31.5-0.90.80.92.12.3
Progressive ratio0.20.51.5-0.3-0.30.20.3-0.30.10.40.30.6-0.6-0.4-0.7-0.8-0.8-0.80.41.1-1.01.20.91.00.8
Food seeking constrained by brief footshock0.50.71.71.01.1-1.2-1.00.9-0.8-0.60.91.0-0.7-0.5-0.6-0.5-0.6-0.60.50.7-1.31.00.60.2-0.1
Seeking ratio, punishment vs. effort0.20.51.60.10.10.1-0.1-0.2-0.1-0.3-0.4-0.80.50.40.70.90.70.7-0.4-1.30.9-1.2-1.2-0.8-0.5
Retroperitoneal fat weight1.25.214.4-2.7-3.33.02.2-2.11.21.6-0.30.5-1.8-2.2-2.0-1.9-1.9-1.91.92.3-2.11.92.43.63.8
Reaction time number correct0.41.42.31.00.8-0.7-1.10.4-1.3-1.51.31.2-1.5-1.5-1.5-1.1-1.4-1.41.20.9-1.31.40.71.11.1
Reaction time mean minus median0.00.31.1-0.6-0.40.40.30.20.60.6-0.5-0.40.50.30.50.20.40.4-0.3-0.41.0-1.0-0.5-0.3-0.4
Reaction time mean minus median AUC0.00.30.7-0.10.0-0.1-0.30.8-0.10.10.40.6-0.6-0.6-0.7-0.8-0.7-0.70.80.60.10.00.20.80.4
Reaction time num false alarms0.40.61.90.71.2-1.2-0.91.1-0.30.20.10.01.00.80.70.80.70.7-0.7-0.40.40.2-0.0-1.3-1.4
Reaction time num false alarms AUC0.10.30.90.70.9-0.9-0.80.7-0.4-0.10.2-0.00.60.50.40.50.40.4-0.3-0.40.30.2-0.1-0.9-0.8
Reaction time trials correct on left0.41.42.31.00.8-0.7-1.10.4-1.3-1.51.31.2-1.5-1.5-1.5-1.1-1.4-1.41.20.9-1.31.40.71.11.1
Reaction time trials on left0.41.52.51.00.7-0.7-1.10.4-1.3-1.51.31.2-1.6-1.5-1.5-1.2-1.5-1.51.30.9-1.31.40.71.21.2
Reaction time mean0.10.20.9-0.9-0.70.70.5-0.20.60.8-0.5-0.40.30.20.3-0.20.10.10.1-0.20.6-0.5-0.50.20.2
Reaction time mean AUC0.00.10.3-0.5-0.40.50.2-0.00.10.3-0.1-0.2-0.0-0.1-0.0-0.5-0.2-0.20.4-0.10.5-0.3-0.50.40.4
Median of all reaction times0.10.21.0-1.0-0.80.80.5-0.40.50.7-0.4-0.40.10.10.1-0.3-0.1-0.10.2-0.20.5-0.3-0.50.40.4
Reaction time omissions0.50.92.20.2-0.00.2-0.6-0.1-1.0-1.00.80.6-1.5-1.5-1.1-1.2-1.3-1.31.20.40.10.30.01.31.5
Reaction time false alarm rate0.71.02.70.20.6-0.5-0.20.40.30.7-0.6-0.71.51.41.31.21.21.2-1.2-1.01.1-0.7-0.6-1.6-1.6
Reaction time premature initiation rate1.82.95.7-1.2-1.11.21.3-1.01.51.3-1.8-1.91.91.81.91.81.91.9-1.8-1.92.4-2.3-1.7-1.6-1.2
Reaction time premature initiations0.30.81.9-0.3-0.50.60.5-0.60.60.3-0.9-1.10.90.80.91.01.01.0-1.0-1.21.4-1.3-1.2-0.9-0.5
Std. dev. reaction times0.10.20.6-0.8-0.70.60.50.00.60.8-0.4-0.20.1-0.10.2-0.10.00.00.00.10.6-0.6-0.00.30.2
Reaction time trials completed0.41.52.51.00.7-0.7-1.10.4-1.3-1.51.31.2-1.6-1.5-1.5-1.2-1.5-1.51.30.9-1.31.40.71.21.2
Reaction time trials AUC0.31.11.90.80.5-0.5-0.90.3-1.1-1.21.11.0-1.4-1.3-1.3-1.0-1.3-1.31.10.8-1.31.30.61.11.1
Run reversals in cocaine runway, females6.77.611.4-2.8-2.12.12.6-1.92.92.7-3.1-3.03.13.43.13.03.03.0-3.1-3.02.6-2.5-2.5-2.5-2.2
Run reversals in cocaine runway, males0.30.31.80.81.0-1.0-0.81.3-0.5-0.50.50.5-0.10.1-0.00.0-0.0-0.00.00.1-0.40.40.1-0.4-0.7
Latency to leave start box in cocaine runway0.81.13.10.2-0.0-0.2-0.2-0.0-0.20.10.71.1-1.2-1.4-1.1-0.8-1.1-1.11.31.4-1.81.51.71.21.0
Latency to leave start box in cocaine runway, F0.60.81.90.40.1-0.1-0.4-0.4-0.7-0.60.80.8-1.2-1.4-1.1-0.6-1.2-1.21.40.7-1.00.60.81.11.1
Latency to leave start box in cocaine runway, M0.70.63.3-0.1-0.1-0.20.10.60.30.70.30.9-0.5-0.4-0.5-0.6-0.5-0.50.51.3-1.61.81.40.80.3
Std. dev. time between licks in bursts0.20.31.10.3-0.50.70.2-1.0-0.4-0.70.1-0.3-0.5-0.7-0.5-0.6-0.5-0.50.5-0.20.2-0.0-0.60.61.0
Total sessions with >9 infusions2.73.49.0-2.9-3.02.92.8-2.72.42.1-2.3-2.01.11.41.00.91.11.1-1.1-1.21.1-0.8-1.10.10.3
Short access day 1 total inactive lever presses0.20.30.5-0.7-0.70.70.7-0.60.70.5-0.7-0.70.50.30.50.40.70.7-0.7-0.40.3-0.5-0.2-0.3-0.1
Short access day 10 total inactive lever presses0.10.83.01.61.7-1.6-1.41.2-1.2-1.31.00.7-0.1-0.4-0.0-0.2-0.2-0.20.20.2-0.30.40.2-0.6-0.7
Short access day 1 total infusions0.71.33.9-2.0-1.51.51.4-1.41.51.3-1.5-1.21.01.20.90.90.90.9-0.9-1.00.3-0.5-0.9-0.4-0.4
Short access day 10 total infusions1.01.74.2-2.0-2.02.01.8-2.01.51.1-1.5-1.50.91.20.80.70.90.9-0.9-1.11.1-0.6-1.2-0.10.1
Short access total infusions1.72.35.8-2.4-2.42.32.3-2.22.01.9-1.9-1.61.11.31.00.91.01.0-1.0-1.00.9-0.5-1.0-0.1-0.0
Short access day 1 locomotion0.50.81.5-1.2-0.70.60.7-0.51.21.2-1.1-0.91.11.10.90.91.01.0-1.0-0.80.4-0.5-0.8-0.8-1.0
Short access day 10 total locomotion0.72.95.5-1.7-2.32.32.3-2.31.71.3-2.0-2.11.41.21.41.31.71.7-1.7-1.62.0-1.6-1.5-0.5-0.0
Short access total locomotion1.32.06.0-2.1-2.52.32.3-2.22.12.1-1.7-1.30.70.60.60.50.80.8-0.8-0.40.6-0.3-0.20.30.5
One hour access (0.3 mA shock)0.20.30.9-0.3-0.30.40.2-0.4-0.3-0.30.30.3-0.5-0.4-0.8-0.8-0.7-0.70.70.4-0.40.40.10.90.9
Compulsive drug intake0.50.72.0-0.1-0.30.40.0-0.3-0.6-0.60.60.6-1.3-1.0-1.2-1.1-0.9-0.90.90.7-0.40.40.31.41.4
One hour access (shock baseline)0.00.10.50.20.3-0.4-0.20.4-0.00.10.10.20.20.0-0.0-0.1-0.2-0.20.20.2-0.30.70.3-0.1-0.3
Social response proportion0.81.02.6-0.2-0.20.2-0.3-0.2-0.5-0.60.80.9-1.4-1.1-1.4-1.5-1.4-1.41.41.0-0.91.20.51.61.4
Social responses1.31.73.10.90.6-0.5-1.00.0-1.4-1.51.41.2-1.8-1.8-1.6-1.5-1.6-1.61.61.2-0.70.41.01.51.6
Social time1.11.74.11.11.0-1.1-1.20.9-1.1-1.11.41.5-1.3-1.4-1.3-1.4-1.3-1.31.41.5-1.82.01.31.10.8
Soleus weight2.26.516.5-3.7-3.02.83.2-2.33.54.1-3.2-2.52.82.92.42.32.32.3-2.3-1.50.7-1.3-0.9-1.4-1.4
Bone: stiffness2.95.27.7-2.7-2.12.02.6-1.92.82.7-2.8-2.52.52.22.62.72.62.6-2.6-1.81.5-1.5-0.6-1.9-1.5
Tibialis anterior weight5.318.331.0-5.5-5.15.05.6-4.65.45.2-5.4-4.84.24.14.14.14.24.2-4.2-3.42.5-2.8-2.3-2.4-1.7
Time to tail flick, vehicle, before self-admin0.20.20.6-0.4-0.40.40.5-0.30.60.6-0.6-0.50.60.60.60.40.60.6-0.5-0.20.6-0.8-0.0-0.4-0.3
Time to tail flick, vehicle, after self-admin1.93.96.12.41.9-1.8-2.11.8-2.5-2.42.42.1-2.1-2.3-2.0-2.0-2.0-2.01.91.9-1.51.21.81.41.5
Time to tail flick, test, before self-admin0.40.50.9-0.4-0.00.10.10.10.30.1-0.5-0.70.80.80.90.80.90.9-0.8-1.00.9-0.7-0.8-0.9-0.7
Time to tail flick, test, after self-admin0.80.92.90.20.6-0.2-0.50.1-0.5-1.0-0.2-0.90.90.90.90.70.90.9-0.9-1.51.4-1.3-1.7-1.2-0.9
Delta time to tail flick, vehicle, before/after SA1.21.32.30.80.4-0.4-0.60.4-1.1-1.01.11.1-1.4-1.5-1.4-1.2-1.4-1.41.21.2-1.41.21.11.21.3
Delta time to tail flick, test, before/after SA0.10.20.6-0.3-0.30.40.2-0.50.1-0.1-0.3-0.60.40.50.30.30.30.3-0.3-0.60.6-0.6-0.8-0.2-0.1
Tibia length0.00.10.5-0.6-0.30.10.30.10.60.7-0.30.10.20.20.10.00.10.1-0.00.4-0.40.60.60.1-0.2
Ambulatory time before self-admin0.20.62.10.20.4-0.6-0.00.70.70.9-0.5-0.11.01.00.91.00.90.9-0.9-0.20.6-0.40.3-1.1-1.5
Ambulatory time after self-admin2.64.26.7-1.5-1.11.11.6-1.02.22.1-2.3-2.12.52.62.52.62.52.5-2.6-2.21.1-1.2-1.7-2.3-2.2
Bone: tissue strength0.40.41.2-0.4-0.10.10.3-0.10.50.6-0.6-0.61.11.10.80.70.80.8-0.7-0.50.4-0.6-0.3-0.9-0.9
Total heroin consumption1.92.23.91.00.4-0.3-0.90.2-1.5-1.51.51.3-1.9-1.9-1.9-1.9-1.9-1.92.01.6-1.11.01.21.92.0
Bone: trabecular number0.51.02.2-1.1-1.11.01.3-0.91.31.5-1.2-1.01.11.11.01.01.01.0-1.1-0.40.1-0.40.2-0.6-0.4
Bone: trabecular spacing0.91.23.40.90.8-0.5-1.30.3-1.7-1.81.30.8-1.2-1.0-1.5-1.4-1.5-1.51.50.30.2-0.3-0.51.11.0
Bone: trabecular thickness1.21.66.6-1.9-1.91.52.0-1.12.12.6-1.3-0.30.50.50.50.40.50.5-0.50.9-1.21.21.60.50.4
Bone: trabecular tissue density0.10.10.7-0.00.2-0.30.10.30.20.4-0.10.00.20.20.40.40.40.4-0.40.2-0.40.20.8-0.5-0.4
Water consumed over 24 hours0.91.85.00.31.1-0.9-0.70.9-0.1-0.4-0.4-0.91.51.51.41.51.41.4-1.5-1.61.8-1.6-1.4-2.2-2.0
Number of responses in last shaping day0.20.30.5-0.7-0.40.50.4-0.50.40.2-0.6-0.60.60.70.50.60.60.6-0.6-0.60.5-0.5-0.5-0.4-0.3