Hub : Genes

Rap1gds1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Rap1gds1 0.18 0.06 0.0e+00 0.22 0.22 0.24 0.16 9.8e-24 4.2e-24 4.3e-26 1.6e-17
2 Adipose mRNA stability Rap1gds1 0.12 0.05 3.9e-11 0.04 0.1 0.1 0.1 1.5e-05 7.1e-11 1.3e-11 3.4e-11
3 NAcc gene expression Rap1gds1 0.07 0.03 2.1e-08 0.08 0.07 0.08 0.09 5.9e-10 6.7e-09 6.4e-10 3.1e-10
4 Brain gene expression Rap1gds1 0.42 0.1 0.0e+00 0.44 0.44 0.5 0.43 5.3e-45 2.1e-45 1.8e-52 3.1e-43
5 IL gene expression Rap1gds1 0.24 0.11 4.6e-04 0.1 0.11 0.12 0.09 2.7e-03 1.4e-03 9.6e-04 4.2e-03
6 pVTA gene expression Rap1gds1 0.11 0.05 8.7e-05 0.11 0.07 0.06 0.08 1.3e-05 8.3e-04 1.4e-03 2.4e-04
7 PL mRNA stability Rap1gds1 0.07 0.03 4.6e-08 0.04 0.06 0.06 0.01 1.4e-05 4.3e-07 1.4e-07 1.5e-02
8 OFC gene expression Rap1gds1 0.19 0.09 1.1e-03 0.12 0.09 0.09 0.02 7.9e-04 3.6e-03 3.5e-03 1.1e-01
9 BLA gene expression Rap1gds1 0.17 0.08 1.6e-05 0.05 0.04 0.04 0.07 1.2e-03 3.3e-03 2.5e-03 1.2e-04
10 NAcc mRNA stability Rap1gds1 0.05 0.02 1.6e-06 0.02 0.06 0.06 0.05 4.1e-03 3.1e-07 4.4e-07 1.6e-06
11 OFC mRNA stability Rap1gds1 0.17 0.09 9.7e-03 0.08 0.03 0.05 0.05 5.8e-03 5.7e-02 2.2e-02 3.1e-02
12 Liver gene expression Rap1gds1 0.25 0.08 0.0e+00 0.24 0.23 0.24 0.24 1.2e-26 8.0e-26 2.8e-26 7.3e-27
13 Adipose gene expression Rap1gds1 0.27 0.09 0.0e+00 0.23 0.22 0.23 0.24 1.6e-25 3.4e-24 1.8e-25 7.2e-26
14 Liver intron excision ratio chr2_227546643_227571975 0.06 0.04 3.1e-03 0.01 0.01 0 0 4.8e-02 2.9e-02 9.0e-02 7.9e-02
15 Brain mRNA stability Rap1gds1 0.29 0.09 0.0e+00 0.26 0.31 0.34 0.33 1.5e-24 1.0e-29 1.7e-32 4.9e-31
16 Brain intron excision ratio chr2_227529397_227571975 0.05 0.03 1.2e-03 0.05 0.02 0.02 0.03 2.7e-05 1.0e-02 1.2e-02 1.1e-03
17 Brain intron excision ratio chr2_227546643_227571975 0.03 0.02 4.3e-03 0.03 0.02 0.01 0.02 5.8e-04 6.7e-03 1.7e-02 4.3e-03
18 PL intron excision ratio chr2_227529397_227571975 0.04 0.02 6.3e-04 0.02 0.03 0.03 0.03 3.2e-03 3.1e-04 1.8e-04 3.7e-04
19 PL intron excision ratio chr2_227546643_227571975 0.04 0.02 2.3e-03 0.02 0.02 0.03 0.03 1.4e-03 1.1e-03 1.4e-04 1.6e-04
20 RMTg mRNA stability Rap1gds1 0.22 0.1 2.4e-04 0.05 0.09 0.02 0.06 2.1e-02 1.7e-03 1.2e-01 9.6e-03
21 pVTA intron excision ratio chr2_227529397_227571975 0.18 0.08 4.7e-04 0.03 0.08 0.08 0.06 2.2e-02 1.7e-04 2.4e-04 8.8e-04
22 Liver mRNA stability Rap1gds1 0.07 0.03 4.1e-07 0.04 0.05 0.05 0.05 7.4e-05 1.1e-06 1.4e-06 2.4e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.10.21.7-0.3-0.60.20.1-0.1-0.3-0.4-0.3-0.10.0-0.10.00.1-1.3-0.20.5-0.5-0.70.6-0.5-0.00.1
Area under the delay curve0.40.51.41.00.5-0.90.70.80.70.60.7-0.8-0.40.6-0.7-1.01.20.70.4-0.40.1-0.50.60.10.6
BMI with tail2.47.814.8-3.4-2.73.6-3.5-3.8-3.3-3.4-3.23.43.7-2.72.62.8-1.3-2.8-2.32.3-2.21.61.90.01.3
BMI without tail4.18.416.5-3.9-3.34.1-3.8-3.5-3.8-3.6-3.93.73.2-3.43.43.5-1.5-2.5-1.01.0-1.41.00.6-0.30.1
Body weight2.811.724.9-4.6-3.75.0-4.8-4.2-4.3-4.3-4.34.44.3-4.04.14.0-0.7-2.7-1.41.4-1.00.21.4-0.70.6
Weight adjusted by age1.61.95.41.22.3-1.21.60.91.71.22.0-1.1-1.61.9-1.9-1.9-0.40.70.1-0.1-1.00.90.32.0-0.1
Bone surface0.10.22.4-0.4-0.50.10.2-0.0-0.3-0.4-0.0-0.1-0.20.2-0.2-0.1-1.6-0.20.4-0.4-0.50.4-0.50.50.2
Bone volume0.20.43.1-0.6-0.60.20.10.1-0.5-0.5-0.30.0-0.40.00.00.1-1.7-0.30.8-0.8-0.50.6-0.90.5-0.2
Breakpoint value in progressive ratio session0.30.31.4-0.30.10.6-0.5-1.2-0.5-0.4-0.30.60.8-0.20.10.4-0.3-0.2-0.90.9-0.90.80.6-0.00.1
Number of licking bursts1.31.65.2-0.90.71.1-1.0-2.0-0.5-0.5-0.71.60.8-0.30.20.8-1.3-1.7-1.81.8-2.12.30.81.1-0.2
Context. condit. distance diff. score0.20.32.20.30.10.3-0.2-0.9-0.10.5-0.30.50.4-0.10.40.80.60.30.0-0.00.4-0.7-0.2-1.5-0.7
Locomotion velocity, session 10.50.61.8-0.80.00.7-0.9-0.5-0.8-0.9-0.90.90.5-1.10.90.70.8-0.9-0.50.5-0.30.41.01.30.0
Locomotion distance, session 10.40.54.3-0.21.00.7-0.7-0.7-0.2-0.2-0.31.00.5-0.50.50.52.1-0.2-0.50.50.4-0.51.20.5-0.3
Locomotion velocity, session 20.40.42.20.60.9-0.80.50.50.70.10.7-0.5-0.40.3-0.8-0.80.5-0.2-0.50.5-0.60.80.91.50.5
Locomotion distance, session 20.81.17.40.82.1-0.60.60.60.90.80.8-0.2-1.00.7-0.6-0.72.71.00.3-0.30.9-0.80.81.3-0.7
Locomotion velocity, session 30.40.52.3-0.60.30.9-0.6-0.3-0.9-0.0-0.70.9-0.2-0.81.21.10.60.00.6-0.60.3-0.1-0.8-0.0-1.5
Locomotion distance, session 30.10.20.7-0.2-0.30.3-0.3-0.2-0.6-0.1-0.50.30.3-0.60.80.70.6-0.4-0.20.20.2-0.20.2-0.1-0.2
Stereotopy head waving bouts, day 30.30.41.1-0.8-0.20.8-1.0-0.3-0.6-0.5-0.71.10.5-0.71.00.90.6-0.90.1-0.10.4-0.20.0-0.2-0.3
Stereotopy head waving duration, day 31.31.53.9-1.6-0.71.8-1.9-1.3-1.4-1.1-1.62.01.2-1.41.81.80.3-1.3-0.20.20.20.0-0.1-0.6-0.7
Locomotion velocity, session 71.11.24.8-0.70.50.5-0.4-1.2-0.5-0.7-0.40.80.40.1-0.10.2-1.0-1.1-1.51.5-2.02.11.22.20.3
Locomotion distance, session 70.30.41.70.10.80.4-0.3-1.30.00.2-0.20.80.50.10.00.50.9-0.3-0.90.9-0.70.41.00.3-0.2
Stereotopy head waving bouts, day 70.60.72.50.30.3-0.50.41.40.40.60.4-0.4-0.90.30.2-0.20.70.71.2-1.21.6-1.1-1.3-0.7-1.0
Stereotopy head waving duration, day 71.11.33.50.51.0-0.70.91.70.81.00.8-0.7-1.80.9-0.3-0.70.21.21.7-1.71.3-0.7-1.90.0-1.6
Locomotion velocity, session 80.20.20.60.50.5-0.50.30.10.50.20.3-0.2-0.10.0-0.5-0.50.6-0.2-0.60.6-0.20.30.80.70.4
Locomotion distance, session 80.50.76.00.41.50.4-0.1-1.00.10.7-0.00.70.10.30.00.42.41.0-0.00.00.6-1.00.7-0.3-1.0
Degree of sensitization distance0.40.41.30.30.70.2-0.2-1.20.60.20.40.60.70.6-0.60.10.4-0.3-1.11.1-0.60.31.0-0.50.4
Degree of sensitization stereotypy1.11.23.20.50.3-0.70.81.80.60.80.7-0.8-1.30.5-0.1-0.60.81.31.7-1.71.8-1.5-1.5-0.7-1.0
Conditioned locomotion1.61.95.21.30.5-1.81.82.31.60.91.5-2.0-1.91.4-1.5-1.7-0.41.21.5-1.50.6-0.5-1.10.50.1
Cocaine response after cond. corrected0.70.82.60.40.2-1.00.91.00.6-0.00.6-1.0-0.81.0-1.0-1.3-1.60.60.2-0.2-1.01.2-0.31.50.5
Cocaine response after cond. not corrected1.31.43.61.00.3-1.71.41.71.20.31.2-1.7-0.91.3-1.5-1.9-1.10.6-0.20.2-0.91.10.31.71.3
Cocaine response before conditioning0.30.41.40.70.1-0.70.40.80.70.40.6-0.60.20.1-0.5-0.61.2-0.1-0.60.60.6-0.61.0-0.31.1
Saline control response2.43.19.61.61.8-0.81.01.71.52.11.4-0.7-1.31.2-0.5-0.53.11.81.9-1.93.0-2.8-1.3-2.0-1.8
Bone: connectivity density0.20.30.70.80.4-0.60.90.30.70.60.7-0.8-0.50.8-0.8-0.7-0.60.60.5-0.5-0.1-0.1-0.5-0.60.0
Bone: cortical apparent density0.30.51.1-0.6-0.41.0-0.9-1.0-0.5-0.4-0.61.10.9-0.50.91.00.9-0.4-0.10.10.2-0.40.4-0.9-0.2
Bone: cortical area2.23.27.2-2.7-2.02.4-2.2-2.1-2.3-2.5-2.12.21.9-1.71.81.8-2.1-2.0-0.60.6-1.11.00.20.20.4
Bone: cortical porosity0.20.20.40.00.70.20.10.60.50.20.6-0.1-0.30.4-0.1-0.40.60.60.5-0.50.7-0.6-0.2-0.1-0.2
Bone: cortical porosity0.10.10.3-0.30.40.5-0.20.10.1-0.10.20.20.10.10.0-0.20.30.50.3-0.30.4-0.50.10.0-0.1
Bone: cortical thickness2.44.08.4-2.9-2.52.8-2.6-2.2-2.5-2.7-2.42.42.3-2.02.22.2-1.8-2.1-0.60.6-0.90.60.2-0.40.5
Bone: cortical thickness0.50.62.2-1.0-1.40.8-0.8-0.2-0.4-1.4-0.50.51.3-0.40.50.1-0.7-0.8-0.50.5-0.30.10.80.01.5
Bone: cortical tissue density0.40.51.1-0.5-0.40.9-0.9-1.0-0.5-0.3-0.61.11.0-0.60.91.01.0-0.4-0.10.10.3-0.50.4-1.0-0.2
Condit. Reinf. active minus inactive responses1.21.44.5-1.20.21.8-1.5-2.1-1.1-0.8-1.12.01.0-1.61.11.50.7-1.0-0.60.6-0.40.20.80.2-0.8
Condit. Reinf. active-inactive response ratio3.84.111.7-2.5-0.43.0-2.6-3.4-2.2-1.9-2.13.21.9-2.51.82.4-0.5-2.0-1.51.5-1.61.31.00.6-0.7
Condit. Reinf. active responses0.30.31.80.41.30.20.2-0.30.40.60.30.3-0.6-0.2-0.2-0.01.30.50.5-0.50.4-0.60.10.3-1.1
Condit. Reinf. inactive responses2.63.16.02.01.3-2.02.02.41.81.91.7-2.1-2.11.6-1.4-1.71.42.02.1-2.11.7-1.6-1.1-0.5-0.7
Incentive salience index mean0.60.72.4-0.9-0.01.2-1.1-1.5-0.8-0.7-0.81.40.8-1.20.81.00.1-0.9-0.70.7-0.60.40.70.2-0.2
Condit. Reinf. lever presses0.00.10.4-0.1-0.10.1-0.1-0.00.00.0-0.10.1-0.1-0.30.10.0-0.60.00.3-0.3-0.20.3-0.6-0.3-0.3
Condit. Reinf. active minus inactive responses0.50.71.7-0.7-0.90.6-0.8-0.5-0.2-1.0-0.10.71.2-0.10.30.4-1.3-1.3-1.21.2-0.60.70.4-0.51.1
Condit. Reinf. active-inactive response ratio1.11.23.9-1.2-0.71.1-1.1-1.4-0.8-1.1-0.71.31.2-0.50.61.0-2.0-1.5-1.31.3-1.21.30.0-0.20.3
Condit. Reinf. active responses0.60.82.8-0.6-1.00.5-0.8-0.4-0.0-1.10.10.61.6-0.10.20.2-0.5-1.4-1.61.6-0.50.51.1-0.51.7
Condit. Reinf. inactive responses0.30.31.70.1-0.30.1-0.30.10.2-0.20.30.01.0-0.00.1-0.11.3-0.2-0.70.70.5-0.61.1-0.81.1
Condit. Reinf. lever presses0.40.52.8-0.0-0.70.4-0.5-0.30.3-0.30.30.41.4-0.20.40.30.8-0.4-0.60.60.3-0.70.9-1.71.1
Condit. Reinf. lever reinforcers received0.50.82.7-0.5-1.00.6-0.8-0.40.0-1.00.10.61.6-0.10.30.2-0.2-1.2-1.41.4-0.40.41.1-0.71.7
Conditioned reinforcement - actives1.41.45.00.71.3-0.10.60.40.71.30.7-0.3-1.20.8-0.3-0.20.82.01.4-1.41.8-1.5-1.8-1.4-2.2
Conditioned reinforcement - inactives1.21.43.61.21.6-1.21.31.11.01.41.2-1.1-1.91.3-0.8-0.80.71.61.1-1.10.7-0.5-1.00.6-1.4
Conditioned locomotion2.12.55.21.61.9-1.01.51.01.72.11.9-1.1-1.41.9-1.1-0.90.72.31.3-1.31.7-1.5-1.8-2.1-1.8
Patch foraging indifference point 0 sec0.61.02.71.61.7-1.01.10.11.31.51.3-0.8-0.71.2-1.2-0.81.21.10.1-0.10.5-0.6-0.2-1.1-0.7
Patch foraging indifference point AUC1.21.42.6-1.4-1.41.4-1.6-1.3-1.4-1.2-1.51.41.5-1.61.51.5-0.3-1.6-0.90.90.0-0.00.4-0.70.4
Delay disc. indifference point, 0s delay0.10.10.40.40.2-0.40.50.1-0.00.50.0-0.4-0.6-0.0-0.6-0.5-0.40.20.1-0.10.00.2-0.6-0.2-0.4
Delay disc. indifference point, 16s delay0.10.10.70.0-0.10.2-0.4-0.3-0.4-0.1-0.30.20.4-0.20.10.00.80.1-0.00.0-0.0-0.30.5-0.10.2
Delay disc. indifference point, 2s delay0.91.02.51.1-0.1-1.11.21.61.20.81.3-1.4-1.01.2-0.8-1.20.11.21.0-1.00.7-0.9-0.7-0.60.3
Delay disc. indifference point, 24s delay1.41.43.11.50.7-1.81.61.61.31.01.4-1.7-1.21.5-1.3-1.70.61.40.7-0.70.4-0.6-0.00.20.5
Delay disc. indifference point, 4s delay0.60.61.90.50.6-0.60.7-0.10.40.10.6-0.6-0.20.8-1.0-1.1-0.40.0-0.50.5-1.41.01.11.31.0
Delay disc. indifference point, 8s delay1.01.06.31.10.7-0.90.71.20.80.90.7-0.7-0.60.5-0.4-0.82.51.31.1-1.11.3-1.70.5-0.10.1
Indifference point function ln k0.60.84.01.12.0-0.50.90.11.31.01.2-0.4-0.71.3-1.2-1.01.01.20.1-0.1-0.1-0.10.30.4-0.6
Indifference point function log k0.60.84.01.12.0-0.50.90.11.31.01.2-0.4-0.71.3-1.2-1.01.01.20.1-0.1-0.1-0.10.30.4-0.6
Patch foraging total patch changes 0 sec0.60.92.81.51.7-0.81.1-0.11.11.41.2-0.7-0.61.2-1.2-0.81.21.10.0-0.00.4-0.6-0.1-1.1-0.6
Patch foraging total patch changes 12 sec0.10.20.60.00.20.3-0.3-0.8-0.2-0.1-0.00.20.7-0.20.10.10.3-0.2-0.70.7-0.30.10.5-0.60.3
Patch foraging total patch changes 18 sec0.20.31.70.10.90.30.0-1.3-0.20.3-0.30.30.3-0.2-0.5-0.1-0.2-0.1-0.90.9-0.60.50.3-0.1-0.3
Patch foraging total patch changes 24 sec0.20.21.2-0.01.10.40.1-0.8-0.00.10.40.4-0.00.3-0.3-0.1-0.10.3-0.50.5-0.50.6-0.0-0.1-0.6
Patch foraging total patch changes 6 sec0.50.73.5-0.00.10.8-0.6-1.9-0.3-0.0-0.40.61.3-0.5-0.10.40.1-0.6-1.31.3-0.50.10.6-1.70.3
Patch foraging time to switch 0 sec0.20.31.20.1-1.1-0.40.20.9-0.4-0.1-0.4-0.6-0.4-0.40.50.10.30.41.0-1.00.8-0.8-0.50.00.0
Patch foraging water rate 0 sec0.10.20.8-0.20.70.6-0.2-0.90.2-0.00.40.60.50.4-0.4-0.0-0.5-0.3-0.70.7-0.40.30.2-0.5-0.1
Patch foraging water rate 12 sec0.40.62.1-1.00.31.5-1.1-1.4-0.4-0.8-0.31.41.2-0.20.40.50.3-0.4-1.01.0-0.0-0.00.8-0.30.1
Patch foraging water rate 18 sec1.72.38.4-1.20.11.3-0.9-1.8-0.3-1.3-0.21.31.30.1-0.3-0.1-2.4-1.6-2.02.0-2.92.91.31.31.2
Patch foraging water rate 24 sec0.81.13.7-0.70.91.0-0.6-1.60.1-0.60.11.00.90.3-0.6-0.2-1.2-0.8-1.91.9-1.41.41.21.00.6
Patch foraging water rate 6 sec1.82.67.1-1.60.72.0-1.6-2.7-1.2-1.6-1.12.01.7-0.80.40.6-0.2-1.4-2.02.0-2.11.82.21.80.6
Seeking ratio, delayed vs. immediate footshock1.51.74.61.80.3-2.01.72.01.41.11.3-2.1-1.11.0-1.2-1.50.81.51.1-1.10.7-1.1-0.2-0.30.6
Distance traveled before self-admin0.91.05.2-0.6-0.30.3-0.10.2-0.9-0.2-0.60.0-1.0-0.30.40.7-1.50.91.8-1.80.20.0-2.30.1-2.0
Distance traveled after self-admin0.30.41.1-0.7-0.10.7-0.6-0.8-0.7-0.5-0.50.80.2-0.20.81.1-0.8-0.5-0.10.1-0.70.5-0.40.1-0.7
Extensor digitorum longus weight5.220.444.8-6.3-6.05.6-5.9-3.8-6.7-5.7-6.55.14.3-6.36.35.8-0.8-3.70.3-0.3-0.3-0.20.40.1-0.1
Bone: elastic displacement1.21.42.9-1.7-1.11.5-1.3-1.4-1.5-1.5-1.51.40.9-1.11.11.1-1.7-1.2-0.50.5-1.21.2-0.00.6-0.0
Bone: elastic work3.14.06.9-2.6-2.32.3-2.2-2.2-2.0-2.6-2.12.22.3-1.71.61.6-2.1-2.5-1.81.8-1.81.71.10.71.3
Bone: endosteal estimation0.10.10.6-0.20.2-0.0-0.0-0.2-0.20.0-0.30.2-0.4-0.2-0.10.1-0.6-0.20.0-0.0-0.60.8-0.30.7-0.4
Bone: endosteal perimeter0.20.41.0-0.9-0.40.7-0.8-0.4-0.7-0.6-0.61.00.2-0.90.80.9-0.4-0.9-0.10.10.20.1-0.30.3-0.5
Epididymis fat weight0.30.81.7-1.2-0.71.3-1.2-0.9-0.8-1.2-0.81.31.1-0.80.90.9-0.3-1.1-0.50.5-0.70.60.70.50.4
Delta time in closed arm before/after self-admin0.40.42.20.00.70.3-0.10.0-0.10.6-0.10.4-0.7-0.50.30.60.70.30.6-0.61.1-0.8-0.9-0.4-1.5
Delta time in open arm before/after self-admin0.60.51.70.4-0.1-0.50.30.90.20.50.1-0.5-0.40.10.20.01.01.01.3-1.31.2-1.3-0.7-0.8-0.5
Diff in mean of infusions in LGA sessions0.91.03.30.30.4-0.60.3-0.60.3-0.20.4-0.20.30.4-0.8-0.7-0.8-0.9-1.81.8-1.41.51.61.71.3
Delay discount exponential model param0.60.61.5-1.1-0.61.0-0.9-0.9-0.9-0.7-0.90.90.5-0.80.81.1-1.2-0.8-0.40.4-0.10.5-0.7-0.3-0.6
Extinction: sum of active levers before priming4.04.06.8-2.1-1.91.6-2.0-2.2-2.4-2.6-2.01.42.1-1.81.21.2-1.6-2.3-1.91.9-2.22.02.32.32.0
Active lever presses in extinction session 60.80.72.31.11.5-0.50.80.31.21.11.5-0.6-0.41.3-1.0-0.90.71.20.1-0.10.3-0.40.0-0.8-0.3
Bone: final force0.60.93.1-1.1-0.31.4-1.2-1.8-0.8-0.8-0.81.71.2-0.40.81.1-0.6-1.1-1.11.1-0.60.60.5-0.40.0
Bone: final moment0.61.02.8-1.1-0.31.3-1.1-1.7-0.7-0.9-0.71.61.2-0.30.70.9-0.8-1.3-1.21.2-0.90.80.6-0.10.3
Food consumed during 24 hour testing period0.91.13.5-1.20.21.3-0.8-1.7-0.8-1.3-0.81.10.7-0.10.00.1-0.6-0.6-1.01.0-1.81.41.41.90.5
Glucose0.91.45.5-0.9-0.30.3-0.5-0.8-1.0-1.3-1.20.20.5-0.9-0.2-0.4-1.6-1.1-1.01.0-2.22.11.12.41.0
Heart weight0.20.20.6-0.3-0.60.3-0.70.1-0.1-0.4-0.00.40.7-0.20.60.50.5-0.8-0.50.50.3-0.20.6-0.20.7
Delay discount hyperbolic model param0.80.81.9-1.2-0.61.2-1.1-1.0-1.1-0.8-1.11.20.7-1.11.01.4-0.9-0.9-0.50.50.00.4-0.5-0.3-0.6
Intermittent access intake day 1-15 change0.90.95.3-0.20.3-0.30.6-0.2-0.3-0.20.2-0.5-0.90.9-0.8-0.7-2.30.6-0.30.3-1.61.9-0.51.9-0.3
Intermittent access intake escalation0.60.64.1-0.4-0.1-0.10.3-0.3-0.5-0.4-0.1-0.3-0.50.5-0.4-0.4-2.00.4-0.20.2-1.41.6-0.51.5-0.2
Intermittent access intake escalation 20.90.96.3-0.9-0.60.4-0.3-0.9-1.1-0.9-0.70.20.1-0.10.00.1-2.5-0.1-0.30.3-1.71.7-0.41.20.1
Intermitt. access day 1 inactive lever presses2.02.25.02.11.4-2.21.71.61.91.81.6-1.8-1.11.0-1.6-1.82.11.1-0.00.01.2-1.20.70.00.5
Intermitt. access day 15 inactive lever presses0.20.21.30.20.1-0.40.10.3-0.0-0.2-0.1-0.3-0.1-0.4-0.0-0.31.0-0.5-0.60.60.3-0.10.91.20.6
Intermitt. access escalation Index0.40.41.20.5-0.6-0.50.11.00.20.2-0.1-0.6-0.0-0.60.1-0.31.10.40.5-0.51.1-1.1-0.2-1.00.4
Intermittent access day 1 total infusions0.60.72.2-0.80.51.2-0.9-1.5-0.6-0.8-0.41.20.9-0.20.40.40.1-0.7-1.31.3-0.70.51.10.90.0
Intermittent access day 15 total infusions0.91.02.6-1.0-0.11.1-0.7-1.6-1.0-1.1-0.60.90.7-0.20.30.3-1.1-0.6-1.41.4-1.41.40.81.40.2
Intermittent access terminal intake (last 3 days)0.80.83.3-1.00.31.3-0.8-1.8-0.8-0.9-0.61.20.7-0.00.30.4-0.9-0.3-1.31.3-1.01.00.61.0-0.2
Intermittent access total infusions1.31.44.6-1.30.11.7-1.3-2.1-1.0-1.3-0.81.61.3-0.50.60.7-0.2-0.9-1.71.7-1.31.01.41.10.2
Intermittent access day 1 locomotion0.30.31.0-0.50.50.9-0.4-0.90.1-0.30.21.00.50.50.10.2-0.1-0.5-0.70.7-0.40.40.4-0.0-0.1
Intermittent access day 15 total locomotion0.90.96.6-0.00.6-0.40.8-0.2-0.1-0.00.4-0.5-1.01.1-1.0-0.8-2.60.3-0.30.3-1.31.7-0.71.8-0.3
Intermittent access total locomotion0.60.73.1-0.80.00.8-0.3-1.1-0.6-0.8-0.20.70.20.40.00.2-1.8-0.6-0.90.9-1.31.40.11.1-0.1
Intermittent access standard deviation0.50.52.7-1.0-0.11.1-0.5-1.0-0.5-0.6-0.30.90.00.30.40.4-1.60.40.4-0.4-0.70.5-1.0-0.1-0.9
Left kidney weight1.02.85.5-2.2-1.42.3-2.3-2.3-2.2-2.0-2.32.02.3-1.81.61.50.0-1.0-1.01.0-0.90.21.60.50.8
Right kidney weight1.43.97.4-2.7-1.72.7-2.7-2.3-2.2-2.6-2.42.52.5-2.02.01.8-0.8-1.9-1.31.3-1.41.01.40.70.9
Cocaine induced anxiety0.40.51.30.91.1-1.00.90.70.91.10.9-0.7-0.90.7-0.7-0.60.20.3-0.00.00.20.2-0.40.0-0.3
Post-drug Anxiety0.50.62.20.0-0.6-0.5-0.3-0.2-0.3-0.4-0.3-0.20.7-0.50.10.10.1-1.4-1.31.3-0.50.61.40.81.5
Baseline Anxiety1.51.54.4-0.7-1.60.5-1.1-1.3-1.1-1.6-1.20.41.8-1.00.60.5-0.1-1.4-1.71.7-1.00.62.10.72.0
Tail length0.41.32.7-1.5-1.41.6-1.5-0.9-1.4-1.3-1.61.30.8-1.61.61.5-0.2-0.50.5-0.50.5-0.6-0.5-0.5-0.7
Length with tail0.62.25.3-1.9-2.31.9-2.2-1.1-1.7-2.0-1.71.42.0-1.92.01.7-0.3-1.3-0.20.20.3-0.70.4-0.50.7
Length without tail0.51.14.0-0.8-1.40.7-1.2-0.5-0.3-1.2-0.10.61.9-0.80.80.6-0.3-1.7-1.31.3-0.30.11.4-0.42.0
Times rat made contact with spout1.51.76.1-0.4-0.1-0.30.1-0.7-0.3-1.2-0.1-0.30.60.5-1.0-1.0-1.6-0.8-1.61.6-2.52.31.82.51.9
Lifetime Intake0.60.72.7-0.90.31.4-1.0-1.7-0.8-0.9-0.71.30.9-0.30.60.70.3-0.3-1.01.0-0.70.40.80.6-0.3
Liver weight, left0.20.32.5-0.20.60.3-0.0-0.20.10.20.10.3-0.40.1-0.10.1-1.6-0.5-0.00.0-0.81.1-0.80.4-0.7
Liver weight, right1.42.312.1-0.10.8-0.30.6-0.11.0-0.21.3-0.3-0.21.7-1.4-1.4-3.5-1.1-1.51.5-2.73.10.21.71.2
Locomotor activity0.20.31.60.3-0.0-0.7-0.00.40.0-0.0-0.1-0.40.5-0.1-0.1-0.30.8-0.5-0.90.9-0.10.11.30.61.1
Locomotor testing distance0.40.63.00.5-0.2-0.7-0.20.40.2-0.1-0.2-0.20.8-0.30.0-0.11.7-0.6-1.11.10.6-0.71.70.31.3
Locomotor testing rearing2.03.013.30.90.8-0.80.1-0.90.9-0.20.9-0.41.71.2-1.6-1.40.6-1.0-3.53.5-1.41.03.61.33.1
Locomotion in novel chamber0.50.62.20.9-1.0-1.20.61.00.30.30.3-1.20.4-0.3-0.8-0.90.2-0.1-0.00.00.8-0.90.3-1.11.5
Locomotion in novel chamber post-restriction0.50.63.90.4-0.3-0.50.21.10.40.3-0.0-0.3-0.2-0.20.50.12.0-0.10.8-0.81.6-1.50.2-0.40.2
Fecal boli incidents, locomotor time 10.50.51.60.70.9-1.10.81.30.80.60.9-0.9-0.80.8-0.6-0.9-0.10.2-0.10.1-0.20.8-0.11.00.1
Change in fecal boli incidents, locomotor task0.30.31.7-0.0-0.30.2-0.5-0.6-0.4-0.4-0.30.20.9-0.30.30.30.9-0.1-0.60.60.1-0.61.3-0.00.9
Time >=10cm from walls, locomotor time 10.80.82.6-0.4-1.40.5-0.9-0.9-0.6-0.5-0.90.61.6-1.31.01.20.2-1.1-1.01.0-0.3-0.10.7-1.30.8
Bouts of movement, locomotor time 10.60.63.00.10.1-0.30.4-0.0-0.1-0.20.2-0.6-0.00.4-1.0-1.0-1.70.0-0.80.8-1.61.50.20.90.8
Total resting periods, locomotor time 10.80.93.30.20.5-0.40.5-0.00.2-0.10.4-0.6-0.20.7-1.3-1.2-1.8-0.1-1.01.0-1.81.80.41.30.8
Rest time, locomotor task time 10.80.92.21.30.4-1.31.31.41.10.71.0-1.5-0.80.9-1.4-1.5-0.50.90.4-0.40.1-0.1-0.6-0.30.3
Distance moved, locomotor task time 11.01.12.3-0.7-1.01.1-1.2-1.1-0.9-0.9-0.91.11.3-1.11.31.21.5-1.1-0.90.90.7-0.81.3-0.40.6
Vertical activity count, locomotor time 10.70.71.5-0.7-1.01.0-1.0-0.9-0.7-0.6-1.10.81.1-1.21.01.01.2-0.5-0.40.40.5-0.60.8-0.80.4
Time >=10cm from walls, locomotor time 20.50.61.4-0.9-0.51.1-0.8-0.5-1.1-0.6-1.10.90.6-1.20.91.00.7-0.40.3-0.30.4-0.6-0.2-0.5-0.6
Bouts of movement, locomotor time 21.01.12.01.20.8-0.91.31.21.21.21.4-1.1-1.11.3-1.1-1.20.31.30.9-0.90.8-0.9-0.8-0.8-0.3
Total resting periods, locomotor time 21.41.53.01.61.0-1.31.61.51.61.41.7-1.5-1.21.5-1.5-1.60.31.50.6-0.60.7-0.9-0.7-0.7-0.2
Rest time, locomotor task time 20.91.03.51.6-0.2-1.41.11.61.20.50.9-1.9-0.30.6-1.1-1.30.41.10.5-0.50.4-0.7-0.1-0.90.9
Distance moved, locomotor task time 20.30.40.9-0.6-0.20.9-0.6-0.9-0.9-0.1-0.70.90.2-0.60.70.90.7-0.5-0.10.10.9-0.6-0.1-0.5-0.7
Vertical activity count, locomotor time 20.80.81.6-1.0-1.11.3-0.8-0.6-0.8-0.4-1.10.80.4-1.11.11.30.7-0.40.8-0.81.2-1.1-0.5-1.1-0.7
Light reinforcement 10.50.92.7-0.80.11.4-1.2-1.5-0.7-0.6-0.71.51.4-0.41.01.11.6-0.6-0.90.90.4-0.71.3-0.50.1
Light reinforcement 20.20.31.00.50.4-0.60.70.40.60.10.7-0.6-0.31.0-0.7-0.8-0.30.1-0.00.0-0.60.60.30.50.5
Bone: marrow area0.10.10.7-0.10.3-0.10.1-0.1-0.10.1-0.30.1-0.4-0.1-0.20.0-0.6-0.10.0-0.0-0.60.8-0.30.7-0.4
Bone: maximum diameter0.30.51.9-1.1-0.60.9-0.8-0.7-0.8-1.0-0.60.90.5-0.50.40.5-1.4-1.0-0.20.2-0.50.6-0.20.40.1
Bone: maximum force0.40.72.2-1.0-0.11.2-0.9-1.3-0.4-0.4-0.41.50.8-0.10.50.9-1.2-1.0-0.70.7-0.60.8-0.3-0.6-0.4
Bone: maximum moment0.40.72.2-0.9-0.21.0-0.9-1.2-0.4-0.5-0.31.30.9-0.00.40.7-1.5-1.2-0.90.9-0.91.10.0-0.20.1
Mean time between licks in bursts0.20.20.8-0.3-0.00.2-0.2-0.6-0.70.1-0.60.3-0.4-0.70.40.7-0.7-0.30.1-0.1-0.40.5-0.50.5-0.9
Mean num. licks in bursts0.50.62.40.4-1.0-1.10.71.40.2-0.50.4-1.5-0.20.4-0.5-1.00.30.90.7-0.70.5-0.70.30.31.3
Cd content in liver0.30.31.4-0.3-0.11.0-0.7-1.1-0.4-0.1-0.40.70.8-0.40.50.60.7-0.1-0.20.20.2-0.50.3-1.2-0.2
Co content in liver0.40.41.5-1.10.21.2-0.6-1.0-0.9-0.5-0.81.00.1-0.60.50.60.00.30.2-0.2-0.40.20.00.8-0.8
Cu content in liver1.72.05.52.02.2-1.51.70.32.11.92.0-1.4-0.91.9-2.4-2.00.11.2-0.50.5-0.40.20.4-0.30.3
Fe content in liver1.31.52.61.60.5-1.21.31.31.31.51.2-1.4-1.01.3-0.9-0.80.91.41.3-1.31.5-1.6-0.9-1.6-0.4
K content in liver1.01.02.21.00.5-1.51.21.11.00.71.1-1.3-0.81.2-1.4-1.4-1.0-0.2-0.40.4-0.91.00.31.21.0
Mg content in liver0.60.61.30.91.0-1.00.90.50.90.80.8-0.8-0.61.1-1.2-1.1-0.2-0.0-0.30.3-0.70.70.51.00.5
Mn content in liver0.80.92.6-1.1-1.40.6-1.0-0.6-1.2-1.1-1.10.70.9-1.21.01.0-0.7-1.6-0.60.6-0.80.80.60.80.8
Na content in liver0.70.71.90.80.9-1.01.01.11.10.61.1-1.0-0.80.8-1.3-1.4-0.50.0-0.20.2-0.30.60.21.00.6
Rb content in liver0.81.03.71.01.9-0.51.10.21.21.11.2-0.6-1.11.5-1.6-1.3-0.41.30.1-0.1-0.50.5-0.50.3-0.8
Se content in liver0.20.21.00.2-0.2-0.20.50.3-0.10.3-0.1-0.5-0.5-0.10.0-0.10.20.81.0-1.00.3-0.6-0.5-0.3-0.3
Sr content in liver0.60.61.9-0.2-1.3-0.0-0.40.5-0.4-0.8-0.4-0.20.8-0.70.60.31.4-0.2-0.10.11.0-1.31.1-0.21.3
Zn content in liver4.34.811.63.12.7-2.62.81.03.12.73.1-2.6-1.33.4-3.4-2.9-0.51.6-0.90.9-0.50.40.2-0.60.7
Bone: minimum diameter1.73.16.5-2.5-1.52.5-2.5-2.1-2.5-2.1-2.22.41.8-2.02.32.3-0.7-1.5-0.30.3-0.50.30.30.2-0.3
Time in familiar zone, hab. session 10.20.21.00.30.50.00.10.40.40.50.50.0-0.20.1-0.10.10.20.40.4-0.40.8-0.6-0.8-1.0-0.8
Time in novel zone, hab. session 10.20.21.1-0.0-0.5-0.40.10.30.2-0.3-0.0-0.30.20.1-0.1-0.3-0.5-0.6-0.40.4-0.50.50.60.71.1
Total zone transitions, hab. session 10.81.14.5-0.21.00.8-0.4-0.3-0.60.4-0.80.6-0.6-0.90.60.72.01.31.5-1.51.3-1.5-0.6-0.0-2.1
Total locomotion distance, hab. session 10.30.41.60.81.2-0.30.30.40.70.80.7-0.2-0.50.4-0.4-0.41.20.80.4-0.40.8-0.7-0.1-0.3-0.7
Locomotion velocity, hab. session 10.20.31.50.61.1-0.10.1-0.00.50.60.50.0-0.20.3-0.2-0.11.20.70.2-0.20.6-0.70.1-0.3-0.6
Time in familiar zone, hab. session 20.60.62.9-0.9-1.70.4-0.7-0.1-0.5-1.3-0.50.41.1-0.20.70.4-0.8-1.1-0.70.7-0.40.40.60.11.5
Time in novel zone, hab. session 20.70.72.51.01.6-0.40.70.10.81.30.8-0.4-0.80.4-0.7-0.41.31.00.5-0.50.6-0.8-0.3-0.6-1.1
Total zone transitions, hab. session 21.01.36.2-0.60.21.3-1.1-0.9-0.9-0.1-1.01.20.4-1.11.31.32.50.61.1-1.11.5-1.8-0.1-0.9-1.5
Total locomotion distance, hab. session 20.40.53.1-0.2-0.20.7-0.9-0.6-0.3-0.4-0.40.71.0-0.80.80.61.7-0.3-0.30.30.6-0.91.1-0.50.3
Locomotion velocity, hab. session 20.30.43.20.20.00.3-0.5-0.3-0.0-0.1-0.10.40.7-0.50.60.41.8-0.0-0.20.20.7-1.00.9-0.60.3
Novel to familiar place preference ratio0.30.31.2-0.3-0.00.5-0.5-1.0-0.7-0.6-0.40.40.7-0.60.10.20.6-0.0-0.80.8-0.3-0.01.10.40.4
Novelty place preference0.50.52.1-0.3-0.10.4-0.5-1.1-0.7-0.7-0.40.40.8-0.60.10.00.6-0.1-1.11.1-0.50.11.50.70.8
Time in novel zone, NPP test0.50.62.3-0.5-0.20.6-0.6-1.2-0.8-0.9-0.50.50.9-0.70.20.10.6-0.2-1.11.1-0.50.11.50.60.8
Total zone transitions, NPP test0.91.33.9-1.0-0.11.7-1.5-1.1-1.2-0.7-1.31.60.8-1.41.51.42.00.10.4-0.40.9-1.10.4-0.3-1.0
Total locomotion distance, NPP test0.40.51.4-0.3-0.30.8-1.0-0.9-0.4-0.5-0.40.91.2-0.60.90.81.1-0.3-0.50.50.4-0.70.9-0.80.2
Locomotion velocity, NPP test0.50.72.0-0.5-0.51.0-1.2-1.1-0.6-0.8-0.61.11.4-0.81.01.01.0-0.7-0.90.90.1-0.31.2-0.50.5
Intraocular pressure0.30.42.1-0.3-1.5-0.1-0.20.9-0.4-0.5-0.3-0.10.2-1.00.80.6-0.2-0.20.7-0.70.8-0.6-0.8-1.00.2
Delta distance traveled before/after self-admin0.60.62.50.20.6-0.0-0.1-0.70.6-0.10.50.40.70.6-0.1-0.00.3-0.8-1.61.6-1.00.71.60.41.0
Delta ambulatory time before/after self-admin0.50.62.40.40.8-0.1-0.1-0.70.70.10.50.30.70.7-0.2-0.20.6-0.6-1.51.5-0.90.51.60.10.9
Parametrial fat weight0.40.84.5-0.8-1.30.5-0.5-0.7-1.0-0.9-1.00.30.4-1.00.30.5-2.1-1.0-0.40.4-1.21.4-0.50.20.2
Pavlov. Cond. lever latency0.91.22.4-1.3-1.31.3-1.5-1.0-1.3-1.3-1.31.21.6-1.11.41.31.0-0.6-0.20.20.3-0.71.1-0.20.7
Pavlov. Cond. magazine entry latency0.10.10.30.00.10.1-0.0-0.0-0.20.2-0.2-0.1-0.2-0.30.20.10.50.50.6-0.60.3-0.4-0.3-0.1-0.5
Pavlov. Cond. change in total contacts1.21.34.11.22.0-1.01.50.41.11.51.3-0.9-1.81.4-1.5-1.2-0.01.40.6-0.6-0.10.2-0.70.7-1.2
Pavlov. Cond. index score0.30.30.90.80.4-0.90.90.50.50.70.5-1.0-0.80.5-0.7-0.7-0.40.50.3-0.3-0.10.2-0.50.2-0.2
Pavlov. Cond. latency score0.60.81.71.10.8-1.31.30.80.91.00.9-1.3-1.21.0-1.2-1.2-0.90.70.2-0.2-0.40.5-0.60.5-0.2
Pavlov. Cond. lever contacts0.20.21.10.40.2-0.50.60.20.30.40.3-0.6-0.50.2-0.5-0.6-1.10.1-0.10.1-0.70.9-0.50.2-0.1
Pavlov. Cond. magazine entry number0.10.20.6-0.0-0.2-0.30.10.30.2-0.30.2-0.10.10.3-0.1-0.2-0.8-0.6-0.60.6-0.50.70.20.40.7
Pavlov. Cond. intertrial magazine entries0.20.31.60.10.20.5-0.1-0.50.00.30.00.5-0.10.00.30.80.20.00.1-0.10.5-0.4-0.8-1.3-1.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.90.80.4-0.90.80.40.50.60.5-1.0-0.60.4-0.7-0.8-0.20.50.1-0.1-0.30.3-0.00.40.1
Pavlov. Cond. response bias0.20.20.70.30.4-0.10.20.10.10.50.1-0.2-0.4-0.1-0.0-0.00.20.70.8-0.80.3-0.4-0.8-0.7-0.9
Pavlov. Cond. lever latency0.20.31.10.50.1-0.90.71.00.20.40.3-0.9-1.00.4-0.3-0.40.00.30.6-0.60.3-0.1-0.40.9-0.1
Pavlov. Cond. magazine entry latency0.30.30.80.50.1-0.50.60.60.60.50.6-0.7-0.50.8-0.4-0.6-0.10.90.6-0.60.5-0.6-0.5-0.5-0.0
Pavlov. Cond. change in total contacts0.10.10.5-0.1-0.20.3-0.2-0.70.1-0.2-0.00.30.50.1-0.2-0.1-0.5-0.1-0.60.6-0.60.40.3-0.40.4
Pavlov. Cond. index score0.10.11.0-0.0-0.40.00.10.10.3-0.10.2-0.10.20.3-0.2-0.3-0.70.30.2-0.20.1-0.2-0.5-1.00.3
Pavlov. Cond. latency score0.10.20.70.3-0.0-0.20.40.20.50.20.4-0.4-0.10.6-0.5-0.5-0.70.40.1-0.10.0-0.1-0.5-0.90.2
Pavlov. Cond. lever contacts0.81.02.8-1.1-0.91.5-1.4-1.4-0.8-1.0-0.91.51.7-1.11.11.10.1-0.8-0.60.6-0.2-0.10.4-1.40.2
Pavlov. Cond. magazine entry number0.20.20.7-0.10.30.1-0.3-0.3-0.1-0.0-0.10.40.3-0.40.20.40.9-0.8-0.60.6-0.10.20.80.50.1
Pavlov. Cond. intertrial magazine entries0.91.23.5-0.7-0.80.7-0.9-1.2-0.7-1.1-0.50.61.6-0.60.10.2-0.5-1.4-1.91.9-1.00.91.60.41.6
Pavlov. Cond. lever-magazine prob. diff.0.10.11.0-0.0-0.50.10.10.10.2-0.10.1-0.10.20.2-0.1-0.2-0.80.30.3-0.30.1-0.2-0.5-1.00.2
Pavlov. Cond. response bias0.40.61.6-1.0-0.91.3-1.1-0.8-0.6-0.8-0.71.11.2-0.80.90.8-0.0-0.4-0.20.20.1-0.30.1-1.20.2
Time in closed arm before self-admin0.40.51.60.71.2-0.20.70.01.30.71.0-0.2-0.41.0-1.1-0.8-0.20.8-0.30.3-0.0-0.0-0.4-0.8-0.5
Time in closed arm after self-admin0.60.62.20.91.5-0.10.7-0.31.21.11.0-0.1-0.40.7-0.9-0.60.40.7-0.30.30.5-0.6-0.4-1.4-0.8
Time in open arm before self-admin3.03.36.3-2.0-2.11.4-2.0-1.4-2.2-2.5-2.01.52.0-1.71.61.4-0.7-2.5-1.61.6-1.51.42.01.81.8
Time in open arm after self-admin0.91.03.5-1.0-1.90.5-1.20.0-1.5-1.0-1.30.60.9-1.31.51.30.8-0.50.7-0.71.0-1.20.2-0.10.4
Bone: periosteal estimation0.71.53.5-1.9-1.21.6-1.5-1.4-1.6-1.6-1.51.61.0-1.31.21.3-1.4-1.4-0.20.2-0.90.9-0.00.5-0.1
Bone: periosteal perimeter0.91.54.0-2.0-1.31.6-1.5-1.1-1.7-1.6-1.51.60.9-1.21.51.4-1.3-1.3-0.10.1-0.40.5-0.20.5-0.2
Bone: post-yield work1.72.45.41.82.2-1.61.81.52.22.12.3-1.3-1.72.2-1.9-1.6-0.71.10.3-0.30.30.4-1.4-0.6-0.9
Progressive ratio test 1 active lever presses0.50.52.3-0.80.40.9-0.8-1.1-0.7-0.8-0.90.90.5-0.20.20.10.3-0.4-0.80.8-0.60.51.11.50.1
Progressive ratio test 1 breakpoint0.50.51.9-0.80.40.9-0.8-1.1-0.6-0.8-0.71.00.5-0.10.20.20.2-0.4-0.80.8-0.60.51.01.40.1
Progressive ratio test 1 inactive lever presses1.21.32.91.51.7-1.51.41.11.21.21.2-1.3-1.51.2-1.3-1.61.11.20.3-0.30.2-0.00.21.1-0.2
Progressive ratio test 2 active lever presses2.02.24.1-1.8-1.61.9-1.8-2.0-1.8-2.0-1.91.61.8-1.11.51.3-0.9-1.4-1.41.4-1.01.00.80.50.5
Progressive ratio test 2 breakpoint2.52.85.2-2.0-1.72.0-2.0-2.1-2.0-2.3-1.91.72.0-1.21.71.4-0.8-1.6-1.81.8-1.21.21.30.80.9
Progressive ratio test 2 inactive lever presses0.50.51.2-0.7-0.70.8-1.0-0.7-0.8-0.7-1.10.80.6-1.11.00.90.7-0.8-0.60.60.5-0.10.3-0.0-0.1
Incentive Sensitization - Responses0.50.51.3-0.9-1.00.9-0.6-0.7-0.9-0.6-0.80.50.2-0.41.01.0-1.1-0.10.1-0.1-0.30.5-1.1-0.5-0.9
Incentive Sensitization - Breakpoint0.50.51.7-0.9-1.10.8-0.6-0.7-0.9-0.7-0.70.40.3-0.40.90.9-1.3-0.2-0.10.1-0.40.7-0.9-0.4-0.5
Sum of active levers in priming session hrs 5-60.80.82.9-0.4-0.5-0.0-0.3-0.8-0.6-0.8-0.20.00.6-0.2-0.10.0-1.4-1.0-1.21.2-1.71.71.01.31.1
Progressive ratio1.41.65.3-1.3-2.31.1-1.5-0.1-1.3-1.4-1.61.01.5-2.31.91.50.9-1.10.2-0.21.1-1.00.3-0.90.7
Food seeking constrained by brief footshock1.51.93.7-1.6-0.81.4-1.3-1.7-1.5-1.8-1.11.21.3-1.00.60.8-1.9-1.5-1.81.8-1.71.90.71.00.6
Seeking ratio, punishment vs. effort1.11.33.80.41.8-0.30.8-0.70.60.31.1-0.3-0.71.9-1.4-1.0-1.50.2-1.21.2-1.91.90.41.7-0.1
Retroperitoneal fat weight1.24.07.4-2.2-2.41.8-2.5-1.9-2.2-2.7-2.31.82.5-2.31.81.6-1.4-2.6-1.81.8-1.61.41.50.91.6
Reaction time number correct0.60.83.0-0.00.4-0.40.10.00.8-0.30.6-0.20.20.5-0.6-0.9-0.9-0.7-1.61.6-1.11.21.31.71.4
Reaction time mean minus median0.60.93.10.2-0.5-0.50.61.40.50.50.4-0.6-1.30.20.20.1-0.30.71.8-1.81.2-1.0-1.7-0.5-1.0
Reaction time mean minus median AUC0.60.81.90.6-0.2-0.70.81.20.80.70.7-0.9-1.20.6-0.2-0.3-0.21.21.4-1.41.1-1.0-1.3-0.5-0.7
Reaction time num false alarms0.81.13.40.81.8-0.81.11.31.11.21.0-0.7-1.80.8-0.7-1.00.81.11.0-1.00.50.1-0.90.8-1.3
Reaction time num false alarms AUC0.70.92.60.31.1-0.30.61.30.60.90.5-0.3-1.50.20.1-0.21.11.01.5-1.51.2-0.7-1.30.1-1.6
Reaction time trials correct on left0.60.83.0-0.00.4-0.40.10.00.8-0.30.6-0.20.20.5-0.6-0.9-0.9-0.7-1.61.6-1.11.21.31.71.4
Reaction time trials on left0.50.83.00.00.3-0.50.20.10.8-0.30.6-0.20.20.5-0.6-0.9-0.9-0.6-1.41.4-1.01.21.21.71.4
Reaction time mean0.40.51.7-0.0-1.2-0.60.31.3-0.3-0.1-0.4-0.6-0.7-0.70.40.30.10.01.3-1.31.1-1.0-0.80.2-0.2
Reaction time mean AUC0.40.62.0-0.1-1.3-0.50.21.2-0.4-0.2-0.5-0.5-0.7-0.80.60.40.20.01.4-1.41.0-1.0-0.70.4-0.2
Median of all reaction times0.30.42.2-0.4-1.5-0.2-0.20.7-0.8-0.6-0.9-0.2-0.1-1.30.70.60.2-0.60.7-0.70.7-0.7-0.10.50.3
Reaction time omissions0.71.03.6-0.2-1.3-0.60.61.6-0.4-0.2-0.4-1.0-1.3-0.20.5-0.2-1.10.81.9-1.90.5-0.2-1.70.5-0.4
Reaction time false alarm rate0.70.93.00.40.8-0.20.51.00.20.90.2-0.2-1.2-0.10.20.11.21.01.7-1.71.3-0.9-1.5-0.7-1.7
Reaction time premature initiation rate0.20.20.7-0.5-0.10.8-0.6-0.5-0.2-0.3-0.10.70.4-0.10.40.50.80.20.4-0.40.5-0.80.0-0.8-0.4
Reaction time premature initiations0.10.10.5-0.6-0.10.7-0.6-0.30.1-0.60.00.70.50.00.20.20.2-0.2-0.30.30.1-0.10.50.20.2
Std. dev. reaction times0.70.93.30.3-0.7-0.80.81.60.50.50.5-0.9-1.30.20.1-0.1-0.30.71.8-1.81.3-1.1-1.6-0.4-0.6
Reaction time trials completed0.50.83.00.00.3-0.50.20.10.8-0.30.6-0.20.20.5-0.6-0.9-0.9-0.6-1.41.4-1.01.21.21.71.4
Reaction time trials AUC0.40.62.0-0.10.2-0.2-0.1-0.10.6-0.40.40.00.30.3-0.4-0.6-0.7-0.7-1.41.4-0.81.01.21.41.2
Run reversals in cocaine runway, females1.01.02.41.01.1-1.20.90.60.90.50.8-1.1-0.20.6-1.3-1.60.10.2-1.01.0-1.11.01.21.31.3
Run reversals in cocaine runway, males0.80.83.40.10.8-0.10.2-0.40.7-0.50.7-0.10.31.1-0.9-1.10.20.1-1.11.1-1.20.71.81.81.4
Latency to leave start box in cocaine runway1.11.23.61.21.5-1.21.30.41.20.81.0-1.3-0.81.3-1.7-1.9-0.30.8-0.80.8-0.70.90.81.30.8
Latency to leave start box in cocaine runway, F0.40.41.40.61.2-0.40.80.10.70.50.6-0.7-0.70.9-1.0-1.1-0.60.6-0.20.2-0.50.70.00.7-0.0
Latency to leave start box in cocaine runway, M0.90.91.91.30.4-1.41.10.21.00.70.5-1.2-0.00.8-1.4-1.3-0.20.1-1.31.3-0.40.60.9-0.01.3
Std. dev. time between licks in bursts1.11.37.21.22.7-0.71.2-0.41.31.41.2-0.5-1.11.3-1.6-1.30.11.0-0.80.8-0.60.60.31.2-0.9
Total sessions with >9 infusions0.80.93.80.21.80.60.2-0.20.40.60.30.4-0.80.8-0.3-0.31.31.91.1-1.10.7-0.9-0.6-0.1-1.9
Short access day 1 total inactive lever presses0.70.83.71.21.6-0.60.60.41.21.10.8-0.6-0.30.6-1.0-1.21.90.9-0.40.40.6-0.90.8-0.30.0
Short access day 10 total inactive lever presses2.22.45.72.21.4-2.41.82.22.12.11.8-2.1-1.71.2-1.2-1.32.10.90.8-0.81.2-1.2-0.1-0.2-0.0
Short access day 1 total infusions1.01.03.10.91.8-0.30.80.11.01.30.9-0.3-1.21.3-0.9-0.60.81.60.9-0.90.7-0.8-1.0-0.7-1.7
Short access day 10 total infusions0.70.84.50.82.1-0.20.7-0.00.80.91.0-0.2-0.91.0-0.9-0.81.11.30.2-0.20.4-0.6-0.00.4-1.2
Short access total infusions0.30.31.6-0.11.20.8-0.2-0.7-0.00.20.00.8-0.20.30.00.21.10.80.2-0.20.2-0.40.00.2-1.3
Short access day 1 locomotion0.90.93.80.82.00.20.5-0.51.01.40.90.4-0.61.0-0.7-0.11.01.20.3-0.30.7-0.8-0.8-1.5-1.8
Short access day 10 total locomotion0.91.03.50.71.8-0.41.10.11.21.01.2-0.3-1.11.9-1.7-1.4-0.91.10.3-0.3-0.60.5-0.7-0.1-0.8
Short access total locomotion0.80.82.90.91.7-0.41.00.11.31.11.2-0.3-0.81.7-1.4-1.1-0.11.20.2-0.2-0.0-0.1-0.4-0.4-0.6
One hour access (0.3 mA shock)1.11.32.9-1.3-1.01.3-1.2-1.7-1.3-1.4-1.31.11.2-0.70.91.0-1.3-0.7-1.21.2-1.51.30.40.40.2
Compulsive drug intake0.30.31.8-0.1-0.8-0.30.10.0-0.6-0.5-0.5-0.40.1-0.40.0-0.2-1.1-0.1-0.10.1-1.31.10.20.90.6
One hour access (shock baseline)0.30.41.1-0.4-0.40.6-0.7-1.0-0.3-0.7-0.60.60.9-0.20.50.5-0.0-0.5-1.11.1-0.10.10.70.10.4
Social response proportion0.30.41.40.40.5-0.90.61.20.90.40.6-0.5-0.80.8-0.5-0.6-0.2-0.10.4-0.4-0.20.7-0.30.60.1
Social responses0.60.72.9-0.2-0.3-0.1-0.10.00.4-0.50.20.00.80.7-0.3-0.4-0.9-1.1-1.31.3-1.31.51.10.71.7
Social time0.71.03.11.00.2-0.81.01.40.81.20.7-1.1-0.80.8-0.7-0.60.10.91.0-1.01.1-0.9-1.4-1.8-0.5
Soleus weight0.61.83.8-1.7-1.91.6-1.6-0.7-1.8-1.6-1.81.21.2-1.71.81.50.3-0.51.3-1.30.8-1.2-0.1-0.5-0.0
Bone: stiffness0.20.31.0-0.70.41.0-0.6-0.9-0.2-0.3-0.11.00.50.20.10.2-0.9-0.5-0.60.6-0.60.70.00.0-0.2
Tibialis anterior weight5.418.537.9-6.1-5.95.4-5.6-3.6-6.2-6.0-5.94.74.5-5.55.75.0-1.0-3.9-0.80.8-0.80.31.40.91.2
Time to tail flick, vehicle, before self-admin0.80.81.71.21.2-1.31.11.20.81.30.6-1.2-1.20.7-1.1-1.20.61.00.4-0.40.6-0.2-0.50.2-0.6
Time to tail flick, vehicle, after self-admin2.12.25.7-0.7-1.70.6-0.90.6-1.00.0-1.20.7-0.1-1.52.02.10.7-0.22.1-2.11.7-1.7-2.3-2.4-1.9
Time to tail flick, test, before self-admin3.02.95.51.91.0-1.71.71.91.22.11.2-1.8-1.81.5-1.1-1.01.12.32.1-2.11.9-2.3-1.7-1.6-1.3
Time to tail flick, test, after self-admin0.70.72.1-0.9-0.11.1-0.8-0.6-1.1-0.3-0.91.10.1-1.31.21.40.5-0.20.8-0.80.5-0.5-0.8-0.5-1.4
Delta time to tail flick, vehicle, before/after SA2.02.06.2-1.7-1.81.6-1.6-0.6-1.6-1.0-1.61.70.6-1.82.32.5-0.2-1.20.9-0.90.6-0.6-1.2-1.0-1.2
Delta time to tail flick, test, before/after SA1.51.43.8-1.6-0.31.9-1.5-1.5-1.1-1.1-1.11.90.9-1.61.41.6-0.1-1.2-0.40.4-0.40.60.10.3-0.8
Tibia length0.92.58.8-1.8-3.01.4-2.0-0.5-1.7-2.3-1.81.02.2-2.21.91.4-0.3-1.8-0.40.40.3-0.50.8-0.71.7
Ambulatory time before self-admin1.21.35.9-0.3-0.00.00.20.6-0.70.1-0.4-0.2-1.3-0.20.20.3-1.11.42.3-2.30.7-0.6-2.4-0.0-2.2
Ambulatory time after self-admin0.40.52.60.30.8-0.20.30.20.30.60.4-0.1-0.90.5-0.10.3-0.60.80.9-0.90.0-0.0-1.5-0.6-1.6
Bone: tissue strength2.12.04.2-1.3-0.91.3-1.3-1.9-1.1-1.3-1.01.51.5-0.80.71.0-1.7-2.0-1.91.9-2.02.11.00.60.9
Total heroin consumption0.00.10.2-0.0-0.50.0-0.3-0.2-0.3-0.0-0.00.00.2-0.30.20.5-0.2-0.10.2-0.2-0.0-0.0-0.2-0.4-0.1
Bone: trabecular number0.61.03.20.60.4-0.30.91.00.71.00.7-0.7-1.10.5-0.4-0.3-0.01.21.8-1.80.9-0.9-1.8-1.3-1.2
Bone: trabecular spacing0.81.02.4-0.5-0.90.1-0.5-0.9-0.7-0.9-0.70.41.1-0.50.30.3-0.7-1.4-1.51.5-1.41.21.51.01.4
Bone: trabecular thickness0.20.31.4-0.40.20.40.10.2-0.2-0.1-0.20.1-0.7-0.20.00.0-0.00.41.2-1.20.3-0.4-0.70.5-0.9
Bone: trabecular tissue density0.70.92.50.61.2-1.01.21.30.90.80.9-0.8-1.61.3-1.0-1.1-0.10.91.0-1.0-0.00.3-0.61.4-0.6
Water consumed over 24 hours1.11.33.8-1.5-0.51.3-0.9-1.6-1.4-1.6-1.31.10.5-0.60.30.5-1.3-0.9-0.60.6-1.81.60.82.00.2
Number of responses in last shaping day0.10.10.7-0.20.50.5-0.2-0.3-0.2-0.0-0.10.4-0.3-0.10.20.20.40.40.5-0.50.3-0.1-0.30.3-0.9