Hub : Genes

N4bp2l2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability N4bp2l2 0.05 0.03 4.3e-08 0.04 0.05 0.04 0.04 1.4e-06 1.5e-07 7.0e-07 2.6e-07
2 RMTg intron excision ratio chr12_4977203_5014617 0.2 0.11 2.3e-03 0.07 0.06 0.06 0.06 5.6e-03 1.1e-02 1.3e-02 1.0e-02
3 Brain mRNA stability N4bp2l2 0.08 0.05 1.5e-06 0.08 0.07 0.07 0.07 7.1e-08 4.7e-07 4.5e-07 2.2e-07
4 IC mRNA stability N4bp2l2 0.08 0.05 2.2e-03 0.07 0.06 0.06 0.07 8.0e-04 1.2e-03 2.3e-03 6.8e-04
5 PL mRNA stability N4bp2l2 0.06 0.04 3.8e-06 0.05 0.05 0.05 0.05 1.4e-06 1.8e-06 3.2e-06 1.6e-06
6 Liver alternative polyA XM_063271111.1 0.05 0.03 4.5e-04 0.02 0.01 0.02 0.01 6.4e-03 8.9e-03 6.4e-03 1.4e-02
7 Liver alternative polyA XM_063271111.1 0.06 0.04 5.6e-05 0.01 0.02 0.02 0.01 5.9e-02 2.8e-03 5.2e-03 1.7e-02
8 Adipose alternative polyA NM_001005533.2 0.05 0.03 6.2e-04 0.01 0.01 0.01 0.01 2.2e-02 9.0e-03 7.6e-03 1.4e-02
9 Brain alternative polyA XM_063271111.1 0.04 0.03 4.6e-03 0.01 0.01 0.02 0.01 3.7e-02 1.9e-02 7.8e-03 3.1e-02
10 NAcc alternative polyA NM_001005533.2 0.05 0.04 2.0e-04 0.03 0.04 0.03 0.03 3.6e-05 1.1e-06 8.4e-06 6.1e-05
11 Adipose alternative polyA NM_001005533.2 0.06 0.04 2.2e-04 0.01 0.02 0.02 0.02 1.9e-02 6.6e-03 5.0e-03 6.6e-03
12 Liver alternative polyA NM_001005533.2 0.1 0.06 5.4e-06 -0 0.02 0.02 0.01 5.9e-01 5.1e-03 6.0e-03 5.8e-02
13 Brain alternative polyA XM_063271111.1 0.04 0.03 4.1e-03 0 0.02 0.02 0.01 3.2e-01 1.0e-02 6.1e-03 4.6e-02
14 Adipose alternative polyA XM_063271111.1 0.09 0.05 1.0e-05 0.03 0.02 0.03 0.03 9.3e-05 2.6e-03 4.3e-04 3.5e-04
15 NAcc alternative polyA XM_063271111.1 0.04 0.03 1.1e-04 0.03 0.03 0.03 0.02 3.4e-05 5.9e-05 4.7e-05 2.7e-04
16 Adipose alternative polyA XM_063271111.1 0.07 0.04 1.3e-04 0.01 0.01 0.01 0.01 1.2e-02 1.9e-02 8.9e-03 8.4e-03
17 NAcc alternative polyA XM_063271111.1 0.03 0.02 3.6e-03 0.02 0.01 0.01 0.01 9.6e-04 5.4e-03 4.3e-03 1.4e-02
18 NAcc alternative polyA NM_001005533.2 0.05 0.03 4.2e-05 0.03 0.03 0.03 0.03 2.6e-05 7.5e-06 4.9e-06 2.8e-05
19 Liver alternative polyA NM_001005533.2 0.04 0.03 5.8e-03 -0 -0 -0 -0 5.1e-01 9.1e-01 4.3e-01 5.6e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.72.96.7-2.6-2.5-2.5-2.3-2.31.81.81.41.82.31.4-1.10.6-0.8-0.8-0.8-0.81.30.0
Area under the delay curve0.50.61.21.00.91.11.11.1-0.9-0.90.1-1.1-0.70.10.6-0.2-0.3-0.3-0.3-0.3-0.70.6
BMI with tail1.44.910.3-2.3-3.2-2.0-2.0-1.91.00.73.20.33.13.20.4-0.6-2.6-2.6-2.6-2.61.81.9
BMI without tail2.26.817.3-3.6-4.2-3.1-3.3-3.22.42.23.71.62.53.4-1.00.9-2.2-2.2-2.2-2.20.51.2
Body weight7.934.684.8-8.3-9.2-7.4-7.4-7.45.65.28.24.16.27.3-2.52.0-4.7-4.7-4.7-4.71.32.3
Weight adjusted by age0.30.52.1-1.0-0.7-1.2-0.7-0.70.60.70.20.71.40.3-0.50.2-0.2-0.2-0.2-0.21.1-0.1
Bone surface2.24.18.9-2.9-3.0-2.7-2.4-2.41.81.82.51.62.82.3-0.80.5-1.5-1.5-1.5-1.51.50.7
Bone volume1.22.26.7-1.9-2.1-1.8-1.5-1.51.01.01.70.92.61.7-0.2-0.1-1.3-1.3-1.3-1.31.90.8
Breakpoint value in progressive ratio session0.10.10.4-0.1-0.1-0.1-0.1-0.10.20.20.30.1-0.40.2-0.30.5-0.0-0.0-0.0-0.0-0.6-0.0
Number of licking bursts0.50.72.0-1.2-1.1-1.3-1.2-1.41.21.10.11.30.50.1-0.90.60.20.20.20.20.1-0.7
Context. condit. distance diff. score2.02.44.9-2.2-1.8-2.1-2.1-2.22.22.01.31.80.10.9-1.71.90.10.10.10.1-1.5-0.8
Locomotion velocity, session 10.30.30.80.80.90.70.90.8-0.6-0.4-0.7-0.4-0.7-0.60.10.10.40.40.40.4-0.2-0.1
Locomotion distance, session 11.11.33.51.41.91.21.31.4-0.9-0.7-1.6-0.5-1.4-1.50.10.11.21.21.21.2-0.5-0.7
Locomotion velocity, session 20.20.20.60.40.60.30.40.4-0.10.0-0.5-0.0-0.8-0.6-0.30.40.50.50.50.5-0.6-0.4
Locomotion distance, session 22.12.96.11.12.00.80.80.8-0.00.2-2.30.5-2.5-2.4-1.01.22.32.32.32.3-1.6-2.0
Locomotion velocity, session 30.10.10.5-0.4-0.4-0.4-0.4-0.50.50.40.50.3-0.30.3-0.40.50.00.00.00.0-0.7-0.2
Locomotion distance, session 30.40.41.20.00.1-0.1-0.3-0.40.50.3-0.60.4-1.1-0.7-0.40.40.80.80.80.8-1.0-0.9
Stereotopy head waving bouts, day 31.61.95.1-2.1-1.8-2.1-1.7-1.61.41.51.11.52.21.1-1.00.7-0.6-0.6-0.6-0.61.30.1
Stereotopy head waving duration, day 30.30.42.1-0.1-0.1-0.10.20.4-0.4-0.20.2-0.21.40.40.4-0.5-0.6-0.6-0.6-0.61.50.7
Locomotion velocity, session 70.50.51.41.00.91.01.21.2-1.0-0.80.2-1.0-0.30.00.6-0.2-0.3-0.3-0.3-0.3-0.10.6
Locomotion distance, session 70.50.71.80.30.80.20.40.20.20.3-0.70.3-1.3-1.0-0.71.11.11.11.11.1-1.3-0.9
Stereotopy head waving bouts, day 70.30.30.80.50.80.40.30.4-0.1-0.1-0.9-0.0-0.9-0.8-0.20.30.70.70.70.7-0.8-0.5
Stereotopy head waving duration, day 70.40.41.11.00.90.90.70.8-0.6-0.7-0.7-0.6-1.1-0.60.4-0.30.40.40.40.4-0.8-0.1
Locomotion velocity, session 80.00.00.2-0.3-0.1-0.2-0.2-0.10.20.20.30.10.10.4-0.10.4-0.1-0.1-0.1-0.1-0.40.1
Locomotion distance, session 80.60.91.8-1.3-0.9-1.2-1.2-1.31.41.20.71.1-0.20.4-1.01.30.30.30.30.3-1.1-0.6
Degree of sensitization distance0.50.51.40.91.20.91.01.0-0.7-0.5-0.6-0.5-0.8-0.80.10.20.50.50.50.5-0.4-0.2
Degree of sensitization stereotypy0.40.41.20.90.80.80.70.7-0.5-0.5-0.6-0.6-1.1-0.60.2-0.10.40.40.40.4-0.9-0.2
Conditioned locomotion0.00.00.3-0.0-0.2-0.0-0.1-0.1-0.1-0.1-0.2-0.00.40.10.2-0.4-0.2-0.2-0.2-0.20.50.1
Cocaine response after cond. corrected3.34.07.20.2-1.30.70.40.2-1.2-1.62.0-1.82.02.42.3-2.4-2.7-2.7-2.7-2.72.22.6
Cocaine response after cond. not corrected2.42.85.30.2-1.10.60.40.2-1.0-1.41.9-1.51.52.11.9-1.9-2.3-2.3-2.3-2.31.52.2
Cocaine response before conditioning1.01.23.3-0.30.5-0.4-0.4-0.30.91.0-0.51.0-1.4-1.0-1.41.61.31.31.31.3-1.8-1.3
Saline control response4.15.510.4-2.6-1.4-2.8-2.8-2.73.13.2-0.33.2-0.6-0.8-3.23.01.71.71.71.7-2.0-2.4
Bone: connectivity density3.14.811.6-3.4-3.1-3.3-3.0-3.02.62.62.02.52.51.7-1.81.4-0.7-0.7-0.7-0.70.9-0.2
Bone: cortical apparent density0.30.40.90.80.40.90.70.7-0.7-0.90.3-1.0-0.50.30.8-0.6-0.4-0.4-0.4-0.4-0.30.6
Bone: cortical area0.91.33.4-1.7-1.6-1.5-1.3-1.21.11.21.80.81.11.5-0.70.9-0.9-0.9-0.9-0.9-0.20.5
Bone: cortical porosity0.10.10.3-0.30.0-0.3-0.4-0.30.40.3-0.30.5-0.1-0.3-0.30.40.50.50.50.5-0.2-0.5
Bone: cortical porosity0.30.30.70.20.60.10.00.20.20.1-0.70.3-0.7-0.8-0.40.50.90.90.90.9-0.6-0.8
Bone: cortical thickness0.81.33.2-1.6-1.6-1.5-1.3-1.31.11.11.80.91.11.4-0.70.8-0.8-0.8-0.8-0.8-0.10.4
Bone: cortical thickness1.01.22.3-1.4-1.0-1.4-1.4-1.41.51.50.71.40.00.3-1.41.50.30.30.30.3-1.0-0.7
Bone: cortical tissue density0.30.40.90.80.40.90.70.7-0.8-0.90.2-1.0-0.60.20.8-0.6-0.4-0.4-0.4-0.4-0.30.6
Condit. Reinf. active minus inactive responses0.50.51.31.00.61.20.80.7-0.7-1.0-0.1-1.0-1.1-0.00.9-0.6-0.1-0.1-0.1-0.1-1.00.3
Condit. Reinf. active-inactive response ratio0.40.40.90.70.30.90.60.5-0.6-0.90.3-1.0-0.50.50.9-0.6-0.5-0.5-0.5-0.5-0.60.7
Condit. Reinf. active responses0.60.73.80.70.80.70.30.30.0-0.2-0.6-0.2-2.0-0.8-0.10.40.90.90.90.9-1.9-0.8
Condit. Reinf. inactive responses1.61.95.10.61.30.40.30.30.30.4-1.50.5-2.3-1.8-1.01.11.91.91.91.9-1.9-1.7
Incentive salience index mean0.50.63.40.90.80.90.50.4-0.2-0.5-0.6-0.5-1.8-0.70.20.00.70.70.70.7-1.6-0.5
Condit. Reinf. lever presses0.50.72.90.70.90.60.40.3-0.0-0.1-0.80.0-1.7-1.0-0.30.41.01.01.01.0-1.3-0.9
Condit. Reinf. active minus inactive responses0.91.23.1-1.3-0.8-1.2-1.2-1.11.41.50.51.3-0.50.2-1.51.80.40.40.40.4-1.6-0.7
Condit. Reinf. active-inactive response ratio0.60.72.6-0.7-0.2-0.6-0.7-0.60.91.00.20.9-0.8-0.1-1.11.40.50.50.50.5-1.6-0.7
Condit. Reinf. active responses1.01.43.9-1.4-0.8-1.4-1.3-1.21.61.70.51.4-0.50.1-1.72.00.60.60.60.6-1.8-0.9
Condit. Reinf. inactive responses0.30.40.9-0.8-0.4-0.8-0.7-0.60.80.90.20.80.0-0.1-0.90.90.40.40.40.4-0.5-0.5
Condit. Reinf. lever presses0.10.20.6-0.30.1-0.3-0.2-0.10.40.5-0.20.4-0.3-0.3-0.60.80.40.40.40.4-0.7-0.4
Condit. Reinf. lever reinforcers received0.91.33.8-1.0-0.3-1.1-1.0-0.91.31.50.11.3-0.8-0.2-1.71.90.80.80.80.8-1.8-1.0
Conditioned reinforcement - actives1.83.16.3-2.5-2.1-2.4-2.5-2.52.52.41.12.20.20.7-2.01.90.20.20.20.2-1.3-1.0
Conditioned reinforcement - inactives0.40.51.1-0.8-0.6-0.7-1.0-1.01.00.9-0.21.1-0.1-0.3-0.90.70.60.60.60.6-0.3-0.8
Conditioned locomotion2.02.65.2-2.2-1.9-2.1-2.3-2.22.32.21.02.0-0.10.6-1.91.90.30.30.30.3-1.4-1.0
Patch foraging indifference point 0 sec0.10.20.9-0.2-0.0-0.3-0.3-0.30.20.2-0.70.50.5-0.6-0.2-0.20.50.50.50.50.9-0.5
Patch foraging indifference point AUC0.81.12.5-1.5-1.1-1.5-1.6-1.51.51.40.41.50.40.2-1.21.10.30.30.30.3-0.4-0.7
Delay disc. indifference point, 0s delay4.04.49.7-0.1-1.00.30.30.3-1.0-1.22.8-1.82.32.91.9-1.6-3.1-3.1-3.1-3.10.83.0
Delay disc. indifference point, 16s delay0.20.21.00.50.70.50.50.5-0.2-0.1-0.4-0.2-1.0-0.5-0.20.40.50.50.50.5-0.6-0.3
Delay disc. indifference point, 2s delay2.02.24.91.71.41.91.91.9-1.9-1.90.5-2.2-0.20.61.7-1.2-1.2-1.2-1.2-1.2-0.41.7
Delay disc. indifference point, 24s delay0.30.40.90.90.90.90.90.9-0.7-0.7-0.4-0.7-0.7-0.40.4-0.20.20.20.20.2-0.40.1
Delay disc. indifference point, 4s delay1.01.12.31.00.71.21.21.2-1.3-1.30.6-1.50.20.71.2-0.9-1.1-1.1-1.1-1.1-0.11.4
Delay disc. indifference point, 8s delay0.40.51.80.50.80.50.50.5-0.10.0-0.6-0.0-1.3-0.8-0.40.60.80.80.80.8-1.2-0.6
Indifference point function ln k0.61.01.9-0.10.3-0.3-0.3-0.40.70.8-1.10.9-1.2-1.1-1.11.01.31.31.31.3-1.0-1.4
Indifference point function log k0.61.01.9-0.10.3-0.3-0.3-0.40.70.8-1.10.9-1.2-1.1-1.11.01.31.31.31.3-1.0-1.4
Patch foraging total patch changes 0 sec0.20.41.1-0.20.1-0.3-0.4-0.30.30.4-1.00.70.4-0.9-0.4-0.10.80.80.80.80.9-0.8
Patch foraging total patch changes 12 sec0.20.31.3-0.7-0.7-0.7-0.6-0.50.30.40.20.51.10.2-0.1-0.2-0.2-0.2-0.2-0.21.10.0
Patch foraging total patch changes 18 sec0.20.30.9-0.6-0.5-0.6-0.7-0.60.40.4-0.40.70.8-0.2-0.3-0.10.20.20.20.20.9-0.4
Patch foraging total patch changes 24 sec1.12.04.0-0.50.4-0.8-0.7-0.61.11.3-1.61.7-0.7-1.8-1.61.31.91.91.91.9-0.4-2.0
Patch foraging total patch changes 6 sec0.30.51.1-0.8-0.5-0.9-1.0-0.90.80.8-0.51.10.5-0.4-0.60.30.50.50.50.50.4-0.8
Patch foraging time to switch 0 sec5.110.518.22.00.22.42.52.5-3.4-3.62.2-4.02.52.84.1-3.9-3.7-3.7-3.7-3.73.24.3
Patch foraging water rate 0 sec3.67.614.4-2.6-1.2-3.0-2.9-3.03.43.5-1.33.8-1.0-1.7-3.63.22.72.72.72.7-1.7-3.4
Patch foraging water rate 12 sec1.32.75.0-0.90.1-1.1-0.9-1.11.61.8-1.21.9-1.3-1.6-2.12.02.02.02.02.0-1.3-2.2
Patch foraging water rate 18 sec1.72.74.7-0.10.9-0.4-0.3-0.31.01.3-1.61.3-2.1-1.9-1.82.02.22.22.22.2-2.0-2.1
Patch foraging water rate 24 sec2.73.77.2-2.2-1.3-2.4-2.2-2.32.52.7-0.42.6-0.4-0.6-2.62.41.51.51.51.5-1.4-2.1
Patch foraging water rate 6 sec1.31.93.2-1.0-0.3-1.2-1.1-1.21.51.6-0.91.8-0.8-1.1-1.81.71.51.51.51.5-0.9-1.8
Seeking ratio, delayed vs. immediate footshock1.11.42.61.51.51.51.41.5-1.6-1.5-1.1-1.30.6-0.71.4-1.6-0.1-0.1-0.1-0.11.50.6
Distance traveled before self-admin0.20.30.70.80.70.70.80.8-0.7-0.7-0.2-0.8-0.5-0.10.5-0.4-0.1-0.1-0.1-0.1-0.10.3
Distance traveled after self-admin0.81.02.20.20.7-0.1-0.0-0.00.50.6-1.10.6-1.5-1.2-1.01.11.31.31.31.3-1.5-1.2
Extensor digitorum longus weight3.011.927.5-5.2-4.9-4.9-5.0-4.94.44.33.53.72.22.9-3.12.9-1.2-1.2-1.2-1.2-1.4-0.4
Bone: elastic displacement0.30.30.6-0.7-0.5-0.7-0.8-0.80.80.70.10.80.1-0.0-0.60.60.40.40.40.4-0.3-0.6
Bone: elastic work2.12.86.5-2.5-2.3-2.5-2.4-2.52.22.11.52.01.11.0-1.61.4-0.2-0.2-0.2-0.2-0.3-0.6
Bone: endosteal estimation0.61.43.3-1.7-1.0-1.8-1.5-1.51.41.70.01.71.1-0.0-1.41.10.40.40.40.40.6-0.9
Bone: endosteal perimeter0.61.43.0-1.5-0.8-1.6-1.4-1.31.51.7-0.01.70.4-0.2-1.71.60.70.70.70.7-0.5-1.0
Epididymis fat weight0.00.10.4-0.10.1-0.1-0.2-0.10.30.4-0.20.3-0.4-0.3-0.50.50.40.40.40.4-0.6-0.4
Delta time in closed arm before/after self-admin0.30.20.7-0.6-0.5-0.6-0.5-0.50.60.60.40.5-0.20.3-0.60.8-0.0-0.0-0.0-0.0-0.8-0.2
Delta time in open arm before/after self-admin2.22.25.12.32.22.02.12.1-1.8-1.7-1.7-1.5-1.1-1.41.2-1.10.60.60.60.60.20.0
Diff in mean of infusions in LGA sessions0.20.30.6-0.5-0.2-0.5-0.5-0.50.60.7-0.20.7-0.3-0.3-0.80.70.50.50.50.5-0.4-0.6
Delay discount exponential model param0.70.71.7-1.2-1.3-1.3-1.3-1.31.00.90.21.11.10.3-0.50.1-0.0-0.0-0.0-0.01.0-0.3
Extinction: sum of active levers before priming0.20.20.50.70.70.60.60.6-0.4-0.4-0.4-0.4-0.7-0.40.2-0.00.30.30.30.3-0.6-0.1
Active lever presses in extinction session 60.10.10.2-0.3-0.1-0.4-0.3-0.30.40.4-0.10.4-0.1-0.2-0.40.40.30.30.30.3-0.2-0.4
Bone: final force1.42.35.3-2.3-2.2-2.2-1.9-2.01.81.81.81.51.41.5-1.21.2-0.7-0.7-0.7-0.7-0.00.1
Bone: final moment1.11.74.2-2.0-1.8-1.9-1.7-1.71.51.61.51.41.41.3-1.11.1-0.6-0.6-0.6-0.60.20.0
Food consumed during 24 hour testing period0.10.20.7-0.6-0.7-0.6-0.7-0.80.60.5-0.10.60.40.1-0.30.00.10.10.10.10.4-0.3
Glucose1.21.84.91.92.01.92.22.2-1.9-1.6-1.2-1.6-0.1-0.81.2-0.80.10.10.10.10.90.6
Heart weight1.21.94.5-0.9-0.3-1.0-1.1-1.11.61.6-0.41.5-1.6-0.8-1.81.91.41.41.41.4-2.1-1.6
Delay discount hyperbolic model param0.60.71.6-1.2-1.1-1.3-1.3-1.31.00.90.01.20.90.1-0.60.20.20.20.20.20.9-0.5
Intermittent access intake day 1-15 change0.51.02.2-1.3-1.0-1.3-1.5-1.41.41.30.11.40.2-0.1-1.10.90.50.50.50.5-0.4-0.9
Intermittent access intake escalation0.40.82.0-1.3-1.0-1.2-1.4-1.41.31.20.21.30.40.1-1.00.70.30.30.30.3-0.3-0.7
Intermittent access intake escalation 20.10.10.3-0.00.1-0.1-0.2-0.20.20.2-0.60.4-0.2-0.5-0.30.10.50.50.50.5-0.1-0.5
Intermitt. access day 1 inactive lever presses0.10.20.5-0.5-0.5-0.5-0.7-0.70.60.5-0.10.70.2-0.1-0.40.20.30.30.30.30.0-0.5
Intermitt. access day 15 inactive lever presses1.42.85.80.6-0.40.90.80.8-1.5-1.71.2-1.71.91.52.2-2.3-2.0-2.0-2.0-2.02.42.1
Intermitt. access escalation Index0.20.20.50.20.50.10.30.20.10.2-0.50.1-0.7-0.6-0.50.50.60.60.60.6-0.6-0.6
Intermittent access day 1 total infusions0.40.72.30.50.80.40.30.40.00.1-0.90.1-1.5-1.0-0.50.71.01.01.01.0-1.5-0.8
Intermittent access day 15 total infusions0.60.92.4-0.40.0-0.5-0.7-0.60.90.9-0.60.9-1.1-0.8-1.11.21.01.01.01.0-1.5-1.1
Intermittent access terminal intake (last 3 days)0.20.31.1-0.00.2-0.1-0.3-0.20.40.4-0.40.4-0.8-0.5-0.60.60.60.60.60.6-1.0-0.7
Intermittent access total infusions0.10.11.00.20.20.20.10.2-0.0-0.0-0.0-0.1-0.8-0.1-0.10.30.20.20.20.2-1.0-0.1
Intermittent access day 1 locomotion0.30.31.30.70.80.70.60.7-0.4-0.4-0.4-0.4-1.1-0.50.00.20.40.40.40.4-1.0-0.2
Intermittent access day 15 total locomotion0.91.73.4-0.8-0.1-1.0-1.1-1.01.41.5-0.61.5-1.3-0.9-1.71.81.41.41.41.4-1.8-1.6
Intermittent access total locomotion0.40.41.90.20.50.10.10.10.20.3-0.50.2-1.2-0.6-0.60.80.70.70.70.7-1.4-0.7
Intermittent access standard deviation0.51.02.3-0.2-0.7-0.0-0.2-0.0-0.5-0.60.9-0.61.51.11.1-1.3-1.3-1.3-1.3-1.31.51.2
Left kidney weight5.324.759.2-7.4-7.7-6.8-6.8-6.85.45.16.14.35.05.3-2.92.2-3.1-3.1-3.1-3.11.20.9
Right kidney weight4.520.449.6-6.5-7.0-5.9-6.0-5.94.54.25.83.55.05.2-2.21.6-3.3-3.3-3.3-3.31.41.3
Cocaine induced anxiety0.10.10.30.30.30.40.40.4-0.2-0.20.1-0.4-0.50.10.10.1-0.1-0.1-0.1-0.1-0.60.2
Post-drug Anxiety4.04.39.02.31.22.62.62.6-2.7-2.80.7-3.00.01.02.7-2.2-1.7-1.7-1.7-1.71.12.3
Baseline Anxiety4.24.99.22.21.02.52.52.5-2.9-2.90.7-3.00.71.13.0-2.7-1.9-1.9-1.9-1.92.12.5
Tail length4.818.742.3-6.5-6.5-6.0-6.0-6.25.35.15.14.32.84.1-3.53.2-1.9-1.9-1.9-1.9-1.0-0.0
Length with tail9.641.997.5-9.7-9.9-8.9-9.0-9.07.67.27.96.05.26.6-4.64.0-3.5-3.5-3.5-3.5-0.80.6
Length without tail6.520.950.5-6.6-7.1-6.0-6.1-6.04.64.25.93.65.05.2-2.11.5-3.3-3.3-3.3-3.31.11.3
Times rat made contact with spout0.60.71.4-1.2-1.1-1.2-1.1-1.21.11.10.61.00.20.5-0.90.9-0.0-0.0-0.0-0.0-0.5-0.3
Lifetime Intake0.10.20.30.60.40.60.50.6-0.5-0.5-0.0-0.6-0.5-0.00.4-0.2-0.1-0.1-0.1-0.1-0.40.3
Liver weight, left2.03.38.4-2.8-2.6-2.9-2.7-2.72.22.21.22.22.11.0-1.40.8-0.3-0.3-0.3-0.31.2-0.5
Liver weight, right1.83.17.8-2.4-2.8-2.2-2.2-2.21.51.32.41.12.12.2-0.50.2-1.5-1.5-1.5-1.51.00.8
Locomotor activity3.35.110.8-2.3-1.1-2.4-2.3-2.32.93.1-0.22.9-1.1-0.7-3.23.31.71.71.71.7-2.7-2.3
Locomotor testing distance1.01.83.5-1.4-0.7-1.5-1.4-1.51.71.8-0.41.9-0.2-0.6-1.81.71.11.11.11.1-0.8-1.5
Locomotor testing rearing0.10.20.90.00.3-0.10.0-0.00.10.2-0.90.40.0-0.7-0.30.10.60.60.60.60.4-0.6
Locomotion in novel chamber1.41.83.5-1.6-1.3-1.7-1.7-1.71.91.80.41.8-0.7-0.0-1.71.60.80.80.80.8-1.1-1.2
Locomotion in novel chamber post-restriction2.23.67.0-1.9-1.0-2.0-2.1-1.92.52.5-0.12.4-1.2-0.6-2.62.61.61.61.61.6-2.1-2.0
Fecal boli incidents, locomotor time 11.11.63.1-1.6-1.3-1.5-1.6-1.61.81.80.61.6-0.40.2-1.61.70.50.50.50.5-1.2-1.0
Change in fecal boli incidents, locomotor task0.90.91.70.50.10.60.60.6-0.9-1.00.6-1.11.10.81.2-1.3-1.1-1.1-1.1-1.11.01.3
Time >=10cm from walls, locomotor time 11.61.73.61.71.31.91.71.7-1.8-1.80.1-1.9-0.10.21.6-1.3-0.8-0.8-0.8-0.8-0.31.3
Bouts of movement, locomotor time 11.11.32.6-1.6-1.4-1.6-1.6-1.61.61.60.71.50.00.4-1.41.30.30.30.30.3-0.6-0.7
Total resting periods, locomotor time 11.11.22.4-1.5-1.3-1.5-1.5-1.51.61.60.71.5-0.10.3-1.41.30.30.30.30.3-0.7-0.8
Rest time, locomotor task time 10.80.92.3-1.4-1.5-1.3-1.3-1.31.01.01.30.80.91.1-0.60.5-0.7-0.7-0.7-0.7-0.00.2
Distance moved, locomotor task time 10.40.71.80.81.10.70.70.7-0.3-0.2-1.1-0.1-1.3-1.1-0.20.41.01.01.01.0-0.9-0.7
Vertical activity count, locomotor time 10.71.63.1-0.30.3-0.3-0.4-0.40.91.0-1.01.1-1.7-1.2-1.41.61.61.61.61.6-1.7-1.6
Time >=10cm from walls, locomotor time 21.21.84.1-0.2-0.80.20.00.0-0.5-0.71.8-1.01.42.01.1-0.9-2.0-2.0-2.0-2.00.11.9
Bouts of movement, locomotor time 20.61.02.0-1.4-1.2-1.2-1.4-1.41.41.30.61.3-0.10.3-1.21.10.30.30.30.3-0.9-0.7
Total resting periods, locomotor time 20.40.81.7-1.3-1.2-1.1-1.3-1.31.21.10.71.10.20.5-0.90.8-0.0-0.0-0.0-0.0-0.5-0.4
Rest time, locomotor task time 20.10.10.30.50.50.40.50.5-0.5-0.5-0.1-0.50.0-0.10.4-0.4-0.1-0.1-0.1-0.10.40.2
Distance moved, locomotor task time 20.20.20.4-0.4-0.3-0.4-0.5-0.50.60.6-0.20.6-0.3-0.2-0.60.50.40.40.40.4-0.4-0.5
Vertical activity count, locomotor time 21.52.04.0-1.8-1.5-1.7-1.9-1.92.02.00.22.0-0.3-0.0-1.81.70.80.80.80.8-1.0-1.3
Light reinforcement 10.41.12.71.51.61.51.61.5-1.1-0.9-0.9-0.9-1.3-1.00.40.10.60.60.60.6-0.5-0.1
Light reinforcement 20.10.20.50.60.60.60.70.6-0.5-0.4-0.7-0.2-0.1-0.50.3-0.20.30.30.30.30.6-0.1
Bone: marrow area0.61.33.2-1.6-1.0-1.8-1.4-1.41.41.6-0.01.71.1-0.1-1.41.10.50.50.50.50.6-0.9
Bone: maximum diameter0.71.43.0-1.7-1.7-1.6-1.5-1.41.21.21.51.01.41.3-0.70.6-0.8-0.8-0.8-0.80.30.3
Bone: maximum force1.12.04.9-2.2-1.8-2.2-1.8-1.91.81.91.21.71.20.9-1.41.4-0.2-0.2-0.2-0.2-0.0-0.4
Bone: maximum moment0.91.64.0-2.0-1.5-2.0-1.6-1.61.61.71.01.71.30.7-1.31.3-0.1-0.1-0.1-0.10.1-0.4
Mean time between licks in bursts0.61.43.31.61.81.41.41.4-1.0-0.9-1.7-0.7-1.2-1.50.4-0.41.11.11.11.1-0.1-0.6
Mean num. licks in bursts0.00.10.20.20.20.30.30.4-0.3-0.30.2-0.4-0.10.20.3-0.1-0.3-0.3-0.3-0.3-0.10.4
Cd content in liver2.42.75.1-0.01.1-0.3-0.3-0.20.91.2-1.71.3-2.0-1.9-1.82.02.22.22.22.2-2.3-2.1
Co content in liver0.50.61.5-0.9-0.6-0.9-1.1-1.21.00.9-0.51.20.3-0.5-0.80.40.70.70.70.70.2-1.0
Cu content in liver0.20.20.80.30.70.20.10.5-0.3-0.1-0.90.00.2-0.7-0.10.20.50.50.50.50.1-0.4
Fe content in liver0.80.92.5-0.8-0.0-0.9-0.9-0.61.11.3-0.31.3-0.3-0.5-1.51.60.90.90.90.9-1.0-1.0
K content in liver0.50.50.90.1-0.40.30.20.2-0.5-0.50.9-0.60.70.80.7-0.6-0.9-0.9-0.9-0.90.60.9
Mg content in liver0.60.61.6-0.7-1.2-0.6-0.6-0.80.30.11.3-0.10.91.10.3-0.3-1.0-1.0-1.0-1.00.30.7
Mn content in liver0.20.20.60.50.20.50.50.4-0.6-0.70.0-0.60.10.10.7-0.8-0.3-0.3-0.3-0.30.60.4
Na content in liver0.60.72.2-1.0-1.3-0.8-0.9-0.90.60.41.50.30.81.2-0.00.0-0.9-0.9-0.9-0.9-0.10.6
Rb content in liver1.72.04.62.12.02.11.91.9-1.6-1.6-1.5-1.4-1.6-1.31.0-0.70.70.70.70.7-0.7-0.1
Se content in liver1.72.04.7-0.6-1.2-0.1-0.3-0.1-0.4-0.42.2-0.71.92.10.9-0.6-2.0-2.0-2.0-2.01.01.9
Sr content in liver0.30.20.6-0.7-0.5-0.7-0.7-0.70.50.50.10.60.80.1-0.30.10.00.00.00.00.7-0.2
Zn content in liver2.22.56.1-2.4-2.1-2.5-2.5-2.21.91.91.11.92.00.9-1.30.9-0.3-0.3-0.3-0.30.6-0.3
Bone: minimum diameter0.10.10.40.10.5-0.00.30.4-0.20.1-0.40.20.5-0.4-0.20.20.30.30.30.30.7-0.2
Time in familiar zone, hab. session 11.01.03.20.60.00.60.70.6-1.0-1.0-0.0-0.91.30.51.2-1.5-0.9-0.9-0.9-0.91.81.1
Time in novel zone, hab. session 10.30.31.2-0.6-0.6-0.6-0.8-0.70.80.70.70.5-0.50.4-0.60.70.00.00.00.0-1.1-0.2
Total zone transitions, hab. session 11.52.06.21.41.81.21.11.0-0.4-0.4-1.8-0.3-2.5-1.8-0.30.71.61.61.61.6-1.9-1.3
Total locomotion distance, hab. session 10.40.51.41.01.11.00.90.9-0.6-0.6-0.6-0.6-1.2-0.60.30.00.50.50.50.5-0.9-0.2
Locomotion velocity, hab. session 10.91.33.41.61.81.51.51.4-1.0-0.9-1.3-0.8-1.6-1.20.30.10.90.90.90.9-1.0-0.5
Time in familiar zone, hab. session 21.11.12.10.2-0.30.40.50.5-0.9-0.90.8-1.01.41.11.2-1.2-1.3-1.3-1.3-1.31.41.4
Time in novel zone, hab. session 21.01.03.10.40.80.20.00.10.30.3-1.00.4-1.8-1.3-0.80.91.31.31.31.3-1.6-1.2
Total zone transitions, hab. session 20.40.51.1-0.5-0.3-0.5-0.6-0.70.80.8-0.10.8-0.8-0.3-0.91.00.60.60.60.6-1.0-0.8
Total locomotion distance, hab. session 20.30.41.10.30.60.30.30.20.10.1-0.70.2-1.1-0.8-0.40.60.80.80.80.8-0.8-0.7
Locomotion velocity, hab. session 20.30.41.20.30.60.20.20.10.10.2-0.70.3-1.1-0.8-0.50.60.90.90.90.9-0.9-0.8
Novel to familiar place preference ratio0.10.10.30.10.30.0-0.00.10.10.2-0.40.2-0.5-0.4-0.30.40.50.50.50.5-0.6-0.4
Novelty place preference0.20.20.50.40.60.30.20.4-0.1-0.0-0.6-0.0-0.7-0.6-0.20.30.50.50.50.5-0.6-0.4
Time in novel zone, NPP test0.10.10.30.20.40.20.10.2-0.00.1-0.40.0-0.6-0.4-0.20.30.40.40.40.4-0.6-0.3
Total zone transitions, NPP test0.30.41.3-0.20.1-0.2-0.3-0.30.60.6-0.40.5-1.0-0.5-0.70.80.70.70.70.7-1.1-0.7
Total locomotion distance, NPP test0.20.32.00.30.50.30.20.20.10.1-0.2-0.0-1.3-0.4-0.30.70.50.50.50.5-1.4-0.4
Locomotion velocity, NPP test0.70.94.00.00.50.0-0.1-0.20.60.6-0.50.5-1.8-0.8-1.01.31.11.11.11.1-2.0-1.1
Intraocular pressure1.11.63.5-1.8-1.4-1.9-1.6-1.81.81.80.61.80.20.2-1.51.40.40.40.40.4-0.5-1.0
Delta distance traveled before/after self-admin1.01.12.1-0.50.1-0.6-0.7-0.71.01.0-1.01.3-0.7-1.1-1.21.11.31.31.31.3-1.0-1.4
Delta ambulatory time before/after self-admin0.60.81.80.40.90.20.20.20.10.2-1.30.5-0.9-1.3-0.60.51.31.31.31.3-0.6-1.1
Parametrial fat weight1.33.15.50.1-1.10.50.40.3-1.0-1.42.0-1.61.82.12.0-2.0-2.4-2.4-2.4-2.42.02.3
Pavlov. Cond. lever latency1.51.94.1-2.0-2.0-1.9-1.7-1.71.31.31.41.22.01.4-0.70.4-0.9-0.9-0.9-0.91.00.3
Pavlov. Cond. magazine entry latency0.20.30.9-0.6-0.3-0.6-0.4-0.60.70.80.10.7-0.1-0.1-0.81.00.40.40.40.4-0.5-0.5
Pavlov. Cond. change in total contacts0.60.61.41.00.71.11.01.0-1.0-1.00.4-1.2-0.40.30.9-0.5-0.4-0.4-0.4-0.4-0.30.7
Pavlov. Cond. index score0.10.10.40.50.50.50.50.4-0.3-0.3-0.1-0.3-0.6-0.20.10.10.20.20.20.2-0.5-0.1
Pavlov. Cond. latency score0.20.30.80.80.80.80.80.7-0.5-0.5-0.3-0.6-0.9-0.40.30.00.30.30.30.3-0.6-0.1
Pavlov. Cond. lever contacts1.21.43.41.81.71.81.71.6-1.3-1.4-1.0-1.3-1.5-0.90.9-0.60.50.50.50.5-0.60.0
Pavlov. Cond. magazine entry number0.30.41.20.50.10.60.40.5-0.7-0.8-0.1-0.80.40.20.9-1.1-0.6-0.6-0.6-0.60.80.7
Pavlov. Cond. intertrial magazine entries0.70.81.91.11.40.90.70.9-0.5-0.6-1.3-0.3-1.1-1.30.2-0.11.01.01.01.0-0.4-0.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.50.40.50.50.4-0.4-0.40.1-0.5-0.40.00.3-0.1-0.1-0.1-0.1-0.1-0.30.2
Pavlov. Cond. response bias0.20.20.8-0.20.1-0.2-0.1-0.20.40.4-0.00.4-0.7-0.3-0.60.80.50.50.50.5-0.9-0.5
Pavlov. Cond. lever latency0.30.51.1-0.4-0.9-0.3-0.4-0.60.1-0.10.8-0.10.90.80.5-0.8-0.8-0.8-0.8-0.81.00.6
Pavlov. Cond. magazine entry latency0.91.13.01.61.61.61.61.7-1.3-1.2-0.6-1.3-1.2-0.60.7-0.20.30.30.30.3-0.70.3
Pavlov. Cond. change in total contacts0.71.11.80.41.10.20.30.40.20.5-1.20.5-1.3-1.3-0.91.31.41.41.41.4-1.3-1.2
Pavlov. Cond. index score0.91.22.71.11.61.01.01.1-0.5-0.2-1.3-0.3-1.7-1.3-0.40.81.21.21.21.2-1.4-0.8
Pavlov. Cond. latency score0.70.92.21.11.51.01.11.1-0.6-0.4-1.1-0.4-1.4-1.1-0.10.50.90.90.90.9-1.2-0.5
Pavlov. Cond. lever contacts0.40.51.30.61.00.50.60.7-0.20.0-0.8-0.1-1.1-0.8-0.40.80.80.80.80.8-1.1-0.5
Pavlov. Cond. magazine entry number1.01.33.2-1.4-1.8-1.4-1.4-1.50.90.71.20.71.61.3-0.1-0.3-1.0-1.0-1.0-1.01.20.5
Pavlov. Cond. intertrial magazine entries0.50.71.8-1.2-0.7-1.3-1.1-1.11.11.20.01.10.3-0.0-1.10.90.40.40.40.4-0.1-0.7
Pavlov. Cond. lever-magazine prob. diff.1.01.33.11.11.71.01.11.2-0.5-0.2-1.3-0.3-1.8-1.4-0.40.81.21.21.21.2-1.5-0.8
Pavlov. Cond. response bias1.01.43.21.01.70.90.91.1-0.3-0.1-1.4-0.1-1.8-1.4-0.61.01.31.31.31.3-1.7-0.9
Time in closed arm before self-admin1.82.34.5-1.8-1.2-1.8-2.0-2.02.12.10.12.1-0.3-0.3-2.01.81.01.01.01.0-1.3-1.5
Time in closed arm after self-admin2.93.15.9-2.0-1.2-2.1-2.1-2.12.42.40.12.3-0.6-0.3-2.42.41.11.11.11.1-1.9-1.7
Time in open arm before self-admin0.00.00.2-0.10.1-0.10.00.00.10.20.10.1-0.30.1-0.30.40.10.10.10.1-0.5-0.0
Time in open arm after self-admin1.21.32.71.61.41.51.61.6-1.6-1.5-0.7-1.5-0.4-0.41.2-1.2-0.1-0.1-0.1-0.10.70.6
Bone: periosteal estimation0.81.84.5-2.1-1.6-2.1-1.7-1.71.61.81.11.71.50.9-1.41.3-0.2-0.2-0.2-0.20.4-0.3
Bone: periosteal perimeter0.40.72.0-1.1-0.4-1.1-0.9-0.71.01.30.31.10.30.1-1.31.40.40.40.40.4-0.6-0.6
Bone: post-yield work0.20.30.6-0.6-0.2-0.7-0.5-0.40.60.8-0.20.80.4-0.2-0.70.70.40.40.40.40.1-0.5
Progressive ratio test 1 active lever presses0.70.92.0-1.4-1.3-1.4-1.4-1.31.21.21.01.00.40.8-0.90.9-0.2-0.2-0.2-0.2-0.4-0.2
Progressive ratio test 1 breakpoint0.70.92.0-1.4-1.3-1.4-1.3-1.31.21.21.01.00.40.8-0.90.9-0.2-0.2-0.2-0.2-0.4-0.1
Progressive ratio test 1 inactive lever presses0.81.22.3-1.4-1.0-1.4-1.5-1.51.51.50.11.50.1-0.1-1.31.10.60.60.60.6-0.4-1.0
Progressive ratio test 2 active lever presses1.41.63.0-1.5-1.0-1.5-1.6-1.61.71.70.21.6-0.6-0.1-1.71.60.80.80.80.8-1.6-1.2
Progressive ratio test 2 breakpoint1.41.62.9-1.4-0.9-1.4-1.6-1.51.71.70.11.6-0.6-0.2-1.71.60.80.80.80.8-1.6-1.2
Progressive ratio test 2 inactive lever presses2.03.26.6-2.4-1.9-2.4-2.6-2.52.52.50.42.50.20.1-2.21.90.80.80.80.8-1.1-1.5
Incentive Sensitization - Responses0.20.30.60.00.2-0.0-0.2-0.20.30.3-0.60.4-0.7-0.6-0.50.50.70.70.70.7-0.8-0.7
Incentive Sensitization - Breakpoint0.30.30.80.10.30.1-0.1-0.10.30.3-0.70.4-0.8-0.7-0.50.50.80.80.80.8-0.9-0.7
Sum of active levers in priming session hrs 5-61.00.91.70.2-0.40.40.40.4-0.7-0.80.9-0.91.11.11.1-1.0-1.3-1.3-1.3-1.31.01.3
Progressive ratio0.60.91.61.00.71.11.01.2-1.2-1.20.1-1.20.60.31.3-1.2-0.8-0.8-0.8-0.80.71.1
Food seeking constrained by brief footshock0.60.82.01.20.91.10.90.9-1.1-1.2-1.1-0.8-0.2-0.71.1-1.40.20.20.20.21.10.1
Seeking ratio, punishment vs. effort0.40.61.5-0.9-0.9-1.0-1.0-1.21.11.0-0.11.0-0.3-0.1-0.90.70.50.50.50.5-0.2-0.8
Retroperitoneal fat weight0.83.46.60.8-0.41.21.11.1-1.6-1.91.7-2.21.32.02.3-2.1-2.4-2.4-2.4-2.41.42.6
Reaction time number correct0.91.63.4-1.1-0.3-1.2-1.3-1.21.51.6-0.91.8-0.3-1.0-1.71.51.41.41.41.4-0.5-1.6
Reaction time mean minus median0.20.53.9-0.10.30.0-0.00.10.40.60.30.3-1.2-0.0-0.81.40.40.40.40.4-2.0-0.3
Reaction time mean minus median AUC0.51.22.50.51.30.40.50.60.10.4-1.10.3-1.6-1.3-1.01.31.31.31.31.3-1.6-1.1
Reaction time num false alarms0.91.34.40.40.90.30.20.10.40.5-1.20.5-2.0-1.2-1.01.31.41.41.41.4-2.1-1.3
Reaction time num false alarms AUC0.60.92.80.10.60.10.0-0.00.50.6-0.90.6-1.5-1.0-0.91.21.21.21.21.2-1.7-1.1
Reaction time trials correct on left0.91.63.4-1.1-0.3-1.2-1.3-1.21.51.6-0.91.8-0.3-1.0-1.71.51.41.41.41.4-0.5-1.6
Reaction time trials on left0.91.63.2-1.1-0.3-1.2-1.2-1.21.41.6-0.91.8-0.3-1.0-1.71.51.31.31.31.3-0.5-1.6
Reaction time mean1.32.15.02.21.92.12.22.2-1.9-1.8-0.6-2.0-1.2-0.41.3-0.9-0.2-0.2-0.2-0.2-0.50.8
Reaction time mean AUC1.32.15.02.22.12.12.22.2-1.9-1.7-0.8-1.9-1.4-0.71.2-0.70.10.10.10.1-0.70.6
Median of all reaction times2.43.37.22.72.22.62.72.7-2.5-2.5-0.8-2.6-1.0-0.42.0-1.7-0.5-0.5-0.5-0.50.11.2
Reaction time omissions0.30.41.20.91.00.81.01.1-0.8-0.6-0.3-0.8-0.4-0.30.4-0.10.00.00.00.0-0.20.3
Reaction time false alarm rate0.30.42.10.60.60.50.50.4-0.2-0.1-0.4-0.3-1.3-0.4-0.20.50.40.40.40.4-1.5-0.3
Reaction time premature initiation rate0.10.10.4-0.00.2-0.10.00.10.20.30.00.1-0.4-0.1-0.40.60.20.20.20.2-0.6-0.2
Reaction time premature initiations0.30.51.2-0.50.1-0.6-0.5-0.40.70.8-0.40.8-0.4-0.5-1.01.10.80.80.80.8-0.7-0.8
Std. dev. reaction times0.20.41.10.91.00.81.01.0-0.7-0.5-0.0-0.8-1.0-0.20.20.30.10.10.10.1-1.00.2
Reaction time trials completed0.91.63.2-1.1-0.3-1.2-1.2-1.21.41.6-0.91.8-0.3-1.0-1.71.51.31.31.31.3-0.5-1.6
Reaction time trials AUC0.91.73.0-0.9-0.0-1.0-1.1-1.01.41.5-1.11.7-0.5-1.2-1.71.51.51.51.51.5-0.6-1.7
Run reversals in cocaine runway, females0.60.61.31.11.01.11.11.1-1.1-1.1-0.6-1.0-0.1-0.40.9-1.0-0.1-0.1-0.1-0.10.50.4
Run reversals in cocaine runway, males2.02.04.1-0.10.6-0.4-0.4-0.40.91.1-1.61.3-1.7-1.8-1.51.52.02.02.02.0-1.0-2.0
Latency to leave start box in cocaine runway0.40.50.90.3-0.20.50.40.3-0.6-0.70.7-0.80.50.80.8-0.8-0.9-0.9-0.9-0.90.40.9
Latency to leave start box in cocaine runway, F1.11.32.5-0.2-1.00.1-0.1-0.2-0.4-0.61.4-0.71.41.51.0-1.1-1.6-1.6-1.6-1.61.11.4
Latency to leave start box in cocaine runway, M0.30.30.90.50.70.40.40.4-0.1-0.1-0.6-0.0-0.9-0.7-0.20.30.70.70.70.7-0.5-0.5
Std. dev. time between licks in bursts0.81.12.0-0.50.1-0.6-0.6-0.61.01.1-0.71.1-1.0-0.9-1.31.41.21.21.21.2-1.4-1.3
Total sessions with >9 infusions0.60.71.20.5-0.10.60.50.5-0.8-0.90.5-1.00.60.71.1-1.1-0.9-0.9-0.9-0.91.01.1
Short access day 1 total inactive lever presses0.50.72.3-0.4-0.9-0.1-0.3-0.3-0.1-0.30.8-0.21.21.00.7-0.9-1.0-1.0-1.0-1.01.50.8
Short access day 10 total inactive lever presses1.02.56.9-1.4-2.2-1.1-1.3-1.30.40.21.80.22.62.00.7-1.2-1.8-1.8-1.8-1.82.31.3
Short access day 1 total infusions1.11.53.11.30.71.31.31.4-1.6-1.6-0.1-1.60.50.31.6-1.7-0.8-0.8-0.8-0.81.81.2
Short access day 10 total infusions0.20.30.60.80.50.80.70.7-0.7-0.7-0.3-0.7-0.3-0.20.6-0.6-0.0-0.0-0.0-0.00.30.3
Short access total infusions1.41.73.21.30.51.31.31.4-1.6-1.70.4-1.80.50.71.8-1.7-1.2-1.2-1.2-1.21.51.5
Short access day 1 locomotion0.10.20.60.50.50.50.50.6-0.4-0.3-0.1-0.5-0.8-0.10.10.10.10.10.10.1-0.60.1
Short access day 10 total locomotion0.10.10.6-0.2-0.3-0.2-0.2-0.1-0.0-0.10.1-0.00.60.20.2-0.4-0.3-0.3-0.3-0.30.80.2
Short access total locomotion0.50.61.31.00.51.01.01.0-1.0-1.10.1-1.1-0.10.21.0-0.8-0.5-0.5-0.5-0.50.30.8
One hour access (0.3 mA shock)4.55.18.5-1.5-0.2-1.8-1.9-1.82.42.6-1.52.8-1.7-1.9-2.92.72.52.52.52.5-2.5-2.9
Compulsive drug intake1.21.43.31.61.81.51.51.4-1.1-1.0-1.7-0.8-1.2-1.50.5-0.51.01.01.01.0-0.0-0.5
One hour access (shock baseline)1.92.95.4-1.9-1.1-2.0-2.0-1.92.32.30.22.2-0.7-0.3-2.32.31.11.11.11.1-2.1-1.6
Social response proportion2.83.26.9-2.6-2.5-2.5-2.3-2.42.22.22.11.70.81.7-1.71.8-0.6-0.6-0.6-0.6-1.2-0.1
Social responses2.02.65.5-1.9-1.1-2.1-1.7-1.82.12.30.32.2-0.2-0.3-2.22.31.11.11.11.1-1.3-1.5
Social time1.72.35.11.92.31.61.91.8-1.1-0.9-1.8-0.8-2.1-1.90.10.31.61.61.61.6-0.9-1.0
Soleus weight0.92.76.2-2.5-2.0-2.4-2.3-2.42.22.21.12.20.90.8-1.81.60.00.00.00.0-0.5-0.7
Bone: stiffness0.50.82.3-1.1-0.5-1.1-0.9-0.91.21.40.21.2-0.1-0.1-1.41.50.50.50.50.5-1.0-0.8
Tibialis anterior weight3.913.229.6-5.4-5.4-5.0-4.9-4.94.24.14.53.43.03.8-2.72.5-2.0-2.0-2.0-2.0-0.80.5
Time to tail flick, vehicle, before self-admin1.11.22.51.10.51.21.21.2-1.3-1.40.7-1.6-0.00.81.4-1.1-1.1-1.1-1.1-1.10.21.4
Time to tail flick, vehicle, after self-admin0.20.20.7-0.10.2-0.1-0.1-0.10.30.4-0.40.4-0.6-0.5-0.60.70.60.60.60.6-0.8-0.5
Time to tail flick, test, before self-admin0.80.82.0-1.4-1.2-1.3-1.3-1.31.21.20.81.10.60.5-1.00.8-0.1-0.1-0.1-0.1-0.0-0.3
Time to tail flick, test, after self-admin0.60.61.20.50.10.60.70.7-0.9-0.90.6-1.00.60.71.0-0.9-0.9-0.9-0.9-0.90.81.1
Delta time to tail flick, vehicle, before/after SA1.11.01.9-0.00.6-0.1-0.2-0.20.60.7-1.30.9-1.0-1.3-1.01.01.41.41.41.4-1.0-1.4
Delta time to tail flick, test, before/after SA0.90.91.81.31.01.31.31.3-1.3-1.4-0.5-1.2-0.1-0.21.2-1.1-0.3-0.3-0.3-0.30.60.6
Tibia length2.77.517.0-3.6-4.1-3.3-3.0-3.02.11.93.81.53.73.6-0.50.3-2.6-2.6-2.6-2.61.71.5
Ambulatory time before self-admin0.00.10.40.20.30.10.20.2-0.1-0.0-0.1-0.1-0.6-0.2-0.20.30.20.20.20.2-0.6-0.1
Ambulatory time after self-admin0.70.91.90.40.90.20.30.30.20.3-1.20.4-1.4-1.3-0.70.81.31.31.31.3-1.2-1.1
Bone: tissue strength0.10.10.9-0.0-0.2-0.1-0.1-0.2-0.1-0.20.0-0.00.60.10.4-0.7-0.2-0.2-0.2-0.20.90.1
Total heroin consumption2.12.45.82.12.42.01.91.9-1.3-1.2-1.8-1.0-2.1-1.80.4-0.01.21.21.21.2-1.5-0.6
Bone: trabecular number1.72.86.9-2.5-2.6-2.4-2.4-2.41.91.81.81.61.61.6-1.10.7-0.9-0.9-0.9-0.90.40.1
Bone: trabecular spacing1.72.35.12.32.22.12.22.2-1.9-1.8-1.6-1.6-0.8-1.31.3-1.10.50.50.50.50.60.2
Bone: trabecular thickness2.02.55.7-2.4-2.3-2.2-2.2-2.21.81.71.71.61.61.5-1.10.9-0.8-0.8-0.8-0.80.30.1
Bone: trabecular tissue density0.30.54.50.1-0.20.30.10.00.10.01.0-0.5-1.30.8-0.10.6-0.5-0.5-0.5-0.5-2.10.5
Water consumed over 24 hours1.62.25.3-2.2-2.1-2.2-2.2-2.32.01.90.81.90.80.7-1.51.2-0.0-0.0-0.0-0.0-0.2-0.7
Number of responses in last shaping day0.20.30.50.60.30.60.60.6-0.7-0.70.0-0.70.20.20.7-0.6-0.4-0.4-0.4-0.40.60.5