Hub : Genes

N4bp2l2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression N4bp2l2 0.08 0.06 4.1e-03 0.05 0.04 0.03 0.04 1.6e-03 1.9e-03 8.0e-03 5.1e-03
2 BLA isoform ratio NM_001005533.2 0.07 0.04 3.2e-03 0.04 0.05 0.04 0.05 3.6e-03 1.1e-03 2.1e-03 7.1e-04
3 NAcc alternative polyA XM_039089150.1 0.03 0.02 7.8e-03 0.02 0.01 0.02 0.01 1.4e-03 2.7e-02 2.4e-03 1.3e-02
4 Brain alternative polyA XM_039089151.1 0.03 0.02 1.0e-02 0.02 0.01 0.01 0.01 7.3e-03 4.3e-02 1.4e-02 6.1e-02
5 RMTg intron excision ratio chr12_141578_178994 0.23 0.12 8.7e-04 0.12 0.1 0.1 0.1 5.1e-04 1.4e-03 1.2e-03 1.3e-03
6 PL isoform ratio NM_001005533.2 0.05 0.03 4.1e-04 0.04 0.04 0.04 0.04 4.6e-05 6.2e-05 4.1e-05 1.7e-05
7 BLA isoform ratio XM_039089150.1 0.06 0.04 2.9e-03 0.05 0.05 0.05 0.05 1.8e-03 9.4e-04 1.6e-03 1.3e-03
8 PL alternative polyA XM_039089150.1 0.04 0.03 3.5e-03 0.03 0.02 0.02 0.02 6.6e-04 1.5e-03 3.3e-03 1.6e-03
9 PL isoform ratio XM_039089150.1 0.05 0.03 5.2e-04 0.03 0.04 0.04 0.04 5.5e-04 5.6e-05 4.1e-05 5.4e-05
10 NAcc isoform ratio XM_039089150.1 0.05 0.03 5.4e-04 0.03 0.03 0.03 0.02 9.7e-05 2.6e-04 9.6e-05 6.7e-04
11 BLA alternative polyA XM_039089150.1 0.06 0.04 4.9e-03 0.03 0.04 0.02 0.04 1.3e-02 3.0e-03 2.4e-02 5.4e-03
12 NAcc alternative polyA XM_039089150.1 0.04 0.03 1.7e-03 0.03 0.02 0.03 0.02 5.3e-04 2.3e-03 2.9e-04 3.5e-03
13 Liver alternative polyA XM_039089151.1 0.07 0.04 5.2e-05 0.01 0.02 0.02 0.01 5.8e-02 1.4e-03 6.4e-03 9.7e-03
14 PL alternative polyA NM_001005533.2 0.03 0.02 7.7e-03 0.01 0.01 0.03 0.01 4.5e-02 1.9e-02 5.4e-04 1.4e-02
15 Brain isoform ratio XM_039089150.1 0.05 0.04 1.5e-03 0.01 0.02 0.03 0.01 2.0e-02 3.7e-03 2.1e-03 1.9e-02
16 Liver alternative polyA XM_039089151.1 0.09 0.05 8.0e-06 0.01 0.02 0.02 0.01 6.0e-02 1.0e-03 2.5e-03 1.1e-02
17 Liver isoform ratio NM_001005533.2 0.06 0.04 4.6e-04 0 0.01 0.01 0 2.1e-01 1.7e-02 5.1e-02 1.1e-01
18 Liver isoform ratio XM_039089152.1 0.04 0.03 3.3e-03 0 0.01 0 0 3.1e-01 6.7e-02 3.7e-01 2.5e-01
19 Adipose alternative polyA XM_039089151.1 0.07 0.04 1.1e-04 0.01 0.01 0.01 0.01 1.6e-02 1.6e-02 1.1e-02 1.2e-02
20 Adipose alternative polyA XM_039089151.1 0.09 0.05 1.9e-05 0.03 0.02 0.03 0.03 2.0e-04 2.7e-03 8.0e-04 5.2e-04
21 Liver isoform ratio XM_039089150.1 0.07 0.04 8.6e-05 0.02 0.02 0.01 0.02 1.6e-03 5.3e-03 4.2e-02 3.7e-03
22 Liver alternative polyA NM_001005533.2 0.04 0.03 2.8e-03 -0 0 0 -0 9.1e-01 1.4e-01 9.0e-02 6.5e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density3.35.610.3-3.0-2.7-2.9-2.83.0-3.22.5-2.7-3.1-3.12.1-2.92.12.1-2.41.9-1.50.31.31.1-1.10.3
Area under the delay curve0.40.51.60.91.10.41.1-0.71.3-0.50.50.90.8-0.00.6-0.90.20.4-1.00.50.30.20.3-0.3-0.2
BMI with tail1.65.111.8-2.9-1.4-2.8-1.42.7-2.11.9-2.6-2.5-2.72.2-2.80.53.4-3.00.1-0.2-0.02.82.6-2.6-0.7
BMI without tail2.14.38.9-2.7-2.2-2.4-2.42.3-1.62.8-2.1-1.9-1.93.0-1.82.02.7-2.11.7-1.91.71.31.1-1.11.2
Body weight12.050.184.4-9.2-7.2-9.0-7.28.8-7.97.8-8.7-8.4-8.47.9-8.25.18.8-8.04.3-4.02.45.54.8-4.81.3
Weight adjusted by age0.60.61.5-1.0-1.1-0.9-1.10.9-1.20.8-0.9-1.1-1.00.6-0.90.90.3-0.80.9-0.60.00.20.1-0.10.1
Bone surface4.68.113.4-3.7-2.9-3.6-2.93.6-3.62.8-3.5-3.6-3.72.7-3.51.93.2-3.31.6-1.30.32.21.9-1.90.2
Bone volume2.95.010.1-2.8-2.0-2.8-2.12.8-3.21.9-2.9-3.1-3.11.7-3.01.22.5-2.61.0-0.6-0.41.91.7-1.7-0.4
Breakpoint value in progressive ratio session0.10.10.7-0.2-0.10.1-0.00.00.60.50.00.40.30.80.30.20.5-0.10.1-0.40.90.0-0.0-0.30.6
Number of licking bursts0.70.81.9-1.1-1.4-0.7-1.41.0-1.21.1-0.8-1.0-0.90.8-0.81.20.3-0.71.2-0.90.4-0.1-0.30.30.7
Context. condit. distance diff. score2.32.76.2-1.9-2.0-1.7-2.11.7-1.12.4-1.6-1.3-1.22.5-1.12.01.7-1.11.8-2.01.90.30.1-0.11.5
Locomotion velocity, session 10.50.61.61.00.80.80.7-1.01.0-0.60.71.01.1-0.41.0-0.4-0.61.3-0.40.20.3-0.7-0.50.50.1
Locomotion distance, session 11.72.24.01.81.31.81.2-1.91.9-1.31.92.01.9-1.21.9-0.7-1.62.0-0.60.40.1-1.3-1.11.10.3
Locomotion velocity, session 20.20.30.70.50.20.20.3-0.60.9-0.20.60.70.7-0.10.7-0.0-0.50.80.0-0.20.5-0.7-0.60.60.4
Locomotion distance, session 22.33.27.81.90.71.90.8-2.12.1-0.92.22.22.2-1.02.40.1-2.42.80.3-0.50.9-2.5-2.32.31.0
Locomotion velocity, session 30.10.10.3-0.2-0.20.0-0.40.10.00.5-0.20.00.10.50.00.40.30.10.3-0.40.5-0.00.0-0.00.4
Locomotion distance, session 30.20.20.60.4-0.00.5-0.1-0.3-0.2-0.10.00.10.4-0.30.40.3-0.70.60.4-0.30.1-0.8-0.80.80.3
Stereotopy head waving bouts, day 32.42.95.1-2.3-2.1-2.0-2.12.1-2.12.0-2.0-2.1-2.01.8-1.91.61.6-1.41.5-1.30.60.70.6-0.60.5
Stereotopy head waving duration, day 30.30.30.8-0.6-0.3-0.8-0.20.6-0.70.2-0.7-0.8-0.80.1-0.9-0.10.7-0.4-0.20.3-0.50.60.7-0.7-0.6
Locomotion velocity, session 70.50.51.60.70.90.71.0-0.81.2-0.50.61.11.0-0.10.8-0.80.10.8-0.90.50.20.10.3-0.3-0.0
Locomotion distance, session 70.70.92.10.80.31.00.2-1.01.30.00.91.21.40.21.30.3-0.71.20.3-0.71.2-1.1-1.01.01.0
Stereotopy head waving bouts, day 70.40.41.01.00.60.50.8-0.70.3-0.70.20.50.8-0.70.7-0.3-0.90.6-0.20.10.2-0.9-0.90.90.3
Stereotopy head waving duration, day 70.30.30.90.90.80.40.9-0.60.2-0.90.10.40.5-0.80.4-0.7-0.70.3-0.60.5-0.3-0.4-0.40.4-0.1
Locomotion velocity, session 80.10.10.5-0.3-0.10.1-0.20.00.70.40.40.40.10.60.20.10.50.10.0-0.20.40.30.3-0.30.4
Locomotion distance, session 80.50.72.1-0.9-1.0-0.5-1.10.6-0.01.3-0.4-0.2-0.31.5-0.21.10.9-0.11.0-1.21.3-0.0-0.00.01.0
Degree of sensitization distance0.80.82.51.10.81.00.8-1.11.6-0.61.21.41.4-0.41.2-0.4-0.71.0-0.40.10.5-0.7-0.60.60.3
Degree of sensitization stereotypy0.20.20.70.80.70.30.8-0.50.1-0.7-0.10.30.5-0.60.4-0.5-0.50.1-0.50.4-0.0-0.3-0.40.40.1
Conditioned locomotion0.10.10.3-0.2-0.1-0.6-0.00.3-0.5-0.1-0.2-0.5-0.5-0.2-0.5-0.10.1-0.5-0.10.2-0.50.30.2-0.2-0.2
Cocaine response after cond. corrected2.62.97.2-1.10.5-1.30.71.2-1.2-0.5-1.1-1.4-1.9-0.4-1.9-1.61.8-1.8-1.81.9-2.22.62.7-2.7-2.3
Cocaine response after cond. not corrected1.81.95.2-0.80.5-1.00.71.0-0.9-0.4-1.0-1.0-1.4-0.2-1.5-1.31.7-1.4-1.51.6-1.62.22.3-2.3-1.7
Cocaine response before conditioning0.81.03.10.5-0.30.8-0.4-0.60.70.60.30.91.30.71.20.9-0.50.90.9-1.21.7-1.3-1.31.31.8
Saline control response2.93.88.7-1.4-2.6-1.5-2.51.4-1.82.4-1.7-1.5-0.92.0-0.82.90.3-0.93.0-2.82.3-1.1-1.51.52.4
Bone: connectivity density4.57.012.6-3.5-3.4-3.0-3.53.2-2.93.3-2.6-3.0-3.13.0-2.72.82.5-2.42.6-2.31.21.20.9-0.91.2
Bone: cortical apparent density0.30.41.10.71.00.60.9-0.70.8-0.70.40.80.7-0.40.6-0.9-0.10.1-0.90.7-0.20.20.3-0.3-0.2
Bone: cortical area1.52.34.5-2.0-1.5-1.8-1.51.8-1.31.8-1.9-1.5-1.52.1-1.51.12.1-1.90.9-1.00.91.41.2-1.20.6
Bone: cortical porosity0.10.10.6-0.3-0.4-0.3-0.30.5-0.80.2-0.7-0.6-0.40.2-0.40.20.1-0.70.2-0.2-0.00.10.0-0.00.1
Bone: cortical porosity0.10.10.50.50.00.40.2-0.30.1-0.2-0.00.30.5-0.20.40.2-0.70.10.2-0.30.4-0.6-0.70.70.4
Bone: cortical thickness1.32.14.0-2.0-1.4-1.6-1.51.7-1.11.8-1.6-1.3-1.42.0-1.41.02.0-1.90.8-0.90.81.41.2-1.20.6
Bone: cortical thickness1.11.32.4-1.1-1.4-0.8-1.51.0-1.01.6-1.3-0.8-0.41.5-0.51.50.8-0.81.5-1.61.5-0.1-0.30.31.3
Bone: cortical tissue density0.30.51.20.81.10.71.0-0.70.8-0.80.50.80.7-0.60.6-0.9-0.20.2-1.00.8-0.30.20.2-0.2-0.3
Condit. Reinf. active minus inactive responses0.50.51.30.91.10.51.2-0.60.8-0.90.50.70.5-0.70.5-1.1-0.20.5-1.10.9-0.50.20.3-0.3-0.8
Condit. Reinf. active-inactive response ratio0.30.31.00.30.80.10.9-0.10.4-0.60.10.20.1-0.3-0.0-0.90.4-0.1-1.00.8-0.50.70.7-0.7-0.7
Condit. Reinf. active responses0.50.61.51.00.70.70.7-0.91.1-0.60.91.00.9-0.51.0-0.3-0.81.2-0.30.10.3-0.8-0.70.70.0
Condit. Reinf. inactive responses1.72.04.91.50.51.40.5-1.61.7-0.51.71.81.7-0.52.00.3-1.82.20.4-0.61.0-2.0-1.91.90.9
Incentive salience index mean0.50.61.21.10.90.80.9-0.90.9-0.80.80.91.0-0.70.9-0.6-0.81.0-0.60.4-0.0-0.6-0.50.5-0.1
Condit. Reinf. lever presses0.60.81.71.00.41.00.4-1.00.9-0.40.71.11.3-0.41.30.0-1.11.20.2-0.30.6-1.2-1.11.10.7
Condit. Reinf. active minus inactive responses1.11.44.1-0.9-1.2-1.2-1.20.9-0.71.7-1.4-0.7-0.31.9-0.51.50.9-0.51.4-1.72.0-0.3-0.40.41.6
Condit. Reinf. active-inactive response ratio0.50.62.7-0.3-0.6-0.3-0.60.20.11.0-0.60.10.31.30.21.00.40.20.9-1.21.7-0.5-0.50.51.2
Condit. Reinf. active responses1.21.75.1-1.0-1.5-1.3-1.31.0-0.71.8-1.5-0.8-0.42.0-0.51.71.0-0.51.6-1.92.3-0.4-0.50.51.8
Condit. Reinf. inactive responses0.40.51.0-0.6-1.0-0.9-0.80.6-0.60.9-0.7-0.6-0.40.9-0.40.90.4-0.40.9-1.00.9-0.2-0.30.30.9
Condit. Reinf. lever presses0.20.20.8-0.2-0.5-0.5-0.40.2-0.20.6-0.5-0.30.00.6-0.10.60.2-0.20.6-0.70.9-0.3-0.40.40.7
Condit. Reinf. lever reinforcers received0.91.35.0-0.6-1.1-1.0-1.10.6-0.31.5-1.1-0.40.01.7-0.11.50.6-0.11.4-1.82.2-0.6-0.80.81.8
Conditioned reinforcement - actives4.24.27.7-2.0-2.7-2.2-2.72.0-1.92.8-2.2-1.9-1.62.6-1.42.81.2-1.42.7-2.72.3-0.2-0.50.51.8
Conditioned reinforcement - inactives0.40.41.0-0.5-0.9-0.6-0.90.6-0.90.7-0.6-0.7-0.50.4-0.51.0-0.0-0.21.0-0.80.4-0.4-0.50.50.6
Conditioned locomotion2.83.35.8-1.8-2.3-2.0-2.41.9-1.72.4-2.0-1.7-1.52.3-1.42.41.2-1.22.3-2.32.0-0.1-0.40.41.7
Patch foraging indifference point 0 sec0.20.31.8-0.2-0.5-0.3-0.40.4-1.3-0.1-0.6-0.9-0.7-0.5-0.60.4-0.3-0.10.5-0.1-0.6-0.3-0.40.4-0.3
Patch foraging indifference point AUC0.70.82.0-0.8-1.3-0.5-1.30.6-0.71.1-0.6-0.5-0.41.0-0.21.40.1-0.31.4-1.31.0-0.5-0.70.71.2
Delay disc. indifference point, 0s delay2.42.710.1-0.80.6-1.00.61.0-0.10.1-0.9-0.6-1.10.7-1.4-1.42.5-1.9-1.81.5-1.03.13.2-3.2-1.6
Delay disc. indifference point, 16s delay0.20.20.70.90.70.20.7-0.50.6-0.40.10.50.6-0.20.5-0.3-0.40.6-0.30.00.5-0.5-0.50.50.2
Delay disc. indifference point, 2s delay1.51.64.31.21.80.71.9-1.01.8-1.21.01.31.0-0.60.7-1.90.40.3-2.11.6-0.51.01.2-1.2-1.2
Delay disc. indifference point, 24s delay0.40.40.90.90.90.50.9-0.70.9-0.60.60.80.7-0.40.7-0.6-0.40.6-0.60.40.1-0.2-0.20.2-0.1
Delay disc. indifference point, 4s delay0.70.72.10.71.20.51.2-0.51.1-0.70.50.80.5-0.30.3-1.30.40.0-1.51.1-0.40.91.1-1.1-0.8
Delay disc. indifference point, 8s delay0.40.51.00.90.50.50.6-0.81.0-0.30.50.91.0-0.10.9-0.2-0.50.8-0.1-0.20.8-0.8-0.80.80.6
Indifference point function ln k0.40.51.80.5-0.30.3-0.3-0.40.20.10.30.30.5-0.10.60.7-1.00.80.9-0.80.7-1.3-1.31.30.8
Indifference point function log k0.40.51.80.5-0.30.3-0.3-0.40.20.10.30.30.5-0.10.60.7-1.00.80.9-0.80.7-1.3-1.31.30.8
Patch foraging total patch changes 0 sec0.20.31.6-0.0-0.5-0.1-0.40.2-1.3-0.1-0.4-0.8-0.5-0.6-0.40.5-0.70.20.7-0.2-0.5-0.7-0.70.7-0.2
Patch foraging total patch changes 12 sec0.30.31.5-0.6-0.6-0.5-0.60.7-1.20.3-0.8-1.0-0.80.0-0.80.40.3-0.50.5-0.2-0.30.20.1-0.1-0.1
Patch foraging total patch changes 18 sec0.20.21.2-0.4-0.7-0.1-0.60.4-1.10.1-0.3-0.7-0.6-0.3-0.50.5-0.4-0.10.6-0.2-0.5-0.2-0.30.3-0.2
Patch foraging total patch changes 24 sec0.91.13.50.3-0.80.4-0.8-0.3-0.50.30.10.00.4-0.10.61.3-1.40.91.5-1.30.9-1.8-1.91.91.1
Patch foraging total patch changes 6 sec0.40.52.1-0.6-1.0-0.7-0.90.7-1.50.4-0.8-1.1-0.9-0.0-0.80.9-0.3-0.31.0-0.6-0.2-0.4-0.50.50.1
Patch foraging time to switch 0 sec3.85.914.50.22.40.12.4-0.10.5-2.00.20.0-0.7-1.4-1.0-3.51.9-1.2-3.83.7-3.33.53.8-3.8-3.6
Patch foraging water rate 0 sec3.04.813.7-1.1-2.9-0.9-2.91.1-1.62.3-1.0-1.1-0.61.6-0.23.5-0.90.13.7-3.32.4-2.3-2.72.72.8
Patch foraging water rate 12 sec1.11.64.80.2-1.10.3-1.0-0.2-0.10.80.10.20.60.50.81.7-1.30.91.9-1.81.7-2.0-2.22.21.8
Patch foraging water rate 18 sec1.21.64.30.9-0.20.8-0.1-0.91.00.20.71.01.40.21.41.0-1.51.41.1-1.31.7-2.0-2.12.11.5
Patch foraging water rate 24 sec2.02.77.0-1.1-2.2-1.0-2.21.1-1.12.1-1.0-0.9-0.61.8-0.32.6-0.0-0.42.6-2.62.2-1.3-1.51.52.2
Patch foraging water rate 6 sec0.71.12.6-0.3-1.20.1-1.10.1-0.10.90.10.10.30.70.51.5-0.80.41.6-1.51.3-1.4-1.51.51.6
Seeking ratio, delayed vs. immediate footshock1.82.04.41.51.51.81.5-1.51.1-1.91.81.31.1-2.11.1-1.6-1.51.3-1.41.6-1.7-0.3-0.10.1-1.3
Distance traveled before self-admin0.30.31.30.50.40.60.6-0.61.1-0.20.70.90.8-0.00.7-0.3-0.30.4-0.30.00.5-0.00.1-0.3-0.1
Distance traveled after self-admin0.30.30.80.3-0.20.5-0.1-0.40.60.20.40.60.70.20.70.5-0.60.50.5-0.70.9-0.9-0.90.50.7
Extensor digitorum longus weight4.015.925.8-4.9-4.8-4.9-4.84.7-4.15.1-4.6-4.3-4.15.0-3.94.14.1-3.83.8-3.72.91.61.1-1.12.1
Bone: elastic displacement0.30.30.8-0.8-0.8-0.6-0.90.6-0.50.8-0.3-0.5-0.60.7-0.50.70.4-0.50.7-0.60.30.20.1-0.10.4
Bone: elastic work3.34.36.5-2.5-2.5-2.5-2.52.5-2.52.5-2.5-2.4-2.22.3-2.22.11.8-2.22.0-1.81.10.90.5-0.51.2
Bone: endosteal estimation0.81.73.8-1.5-1.9-1.4-1.81.4-2.01.5-1.6-1.7-1.41.1-1.31.60.6-0.71.6-1.30.6-0.2-0.30.30.7
Bone: endosteal perimeter0.81.63.1-1.2-1.8-1.2-1.61.2-1.31.6-1.3-1.2-0.91.5-0.81.80.5-0.51.7-1.71.4-0.4-0.60.61.1
Epididymis fat weight0.20.41.2-0.4-0.2-1.1-0.30.7-0.70.5-1.0-0.7-0.70.6-0.80.20.8-1.00.1-0.20.30.70.6-0.6-0.0
Delta time in closed arm before/after self-admin0.30.20.8-0.1-0.40.2-0.3-0.10.50.50.20.40.50.60.50.5-0.00.20.5-0.70.9-0.4-0.50.80.9
Delta time in open arm before/after self-admin2.82.74.22.01.92.01.9-1.91.8-2.12.01.81.7-2.01.6-1.7-1.81.7-1.51.5-1.1-0.7-0.50.3-1.0
Diff in mean of infusions in LGA sessions0.60.62.60.3-0.20.3-0.3-0.40.40.30.30.50.70.20.80.7-0.70.80.7-0.80.9-1.4-1.61.51.2
Delay discount exponential model param0.60.62.2-1.1-1.1-0.6-1.20.9-1.50.6-0.7-1.2-1.10.1-0.90.80.1-0.70.9-0.4-0.60.20.1-0.1-0.1
Extinction: sum of active levers before priming1.21.22.31.41.11.31.1-1.41.4-1.01.21.41.5-0.91.4-0.7-1.21.4-0.60.40.1-1.1-1.00.70.2
Active lever presses in extinction session 60.10.10.7-0.2-0.30.2-0.30.00.10.30.20.20.20.30.30.3-0.00.20.3-0.30.3-0.5-0.70.30.8
Bone: final force2.64.28.3-2.5-2.2-2.5-2.12.4-2.52.4-2.9-2.4-2.12.4-2.21.82.3-2.21.5-1.61.21.20.9-0.91.0
Bone: final moment2.23.56.9-2.3-2.0-2.3-1.92.2-2.32.1-2.6-2.2-1.92.2-2.01.62.1-2.21.4-1.41.01.20.9-0.90.8
Food consumed during 24 hour testing period0.20.20.7-0.6-0.7-0.7-0.60.6-0.80.3-0.4-0.8-0.80.1-0.60.50.0-0.40.5-0.2-0.2-0.0-0.10.1-0.2
Glucose0.40.61.50.61.20.21.1-0.50.9-0.90.60.60.4-0.60.3-1.20.1-0.1-1.21.0-0.60.60.7-0.7-0.9
Heart weight1.72.56.10.3-1.10.1-1.1-0.50.71.00.50.71.00.91.21.9-1.31.32.1-2.22.5-2.3-2.52.52.5
Delay discount hyperbolic model param0.60.72.1-1.1-1.2-0.6-1.30.9-1.50.7-0.7-1.1-1.00.2-0.81.00.0-0.61.1-0.6-0.3-0.0-0.20.20.2
Intermittent access intake day 1-15 change1.01.02.4-1.1-1.5-0.8-1.50.9-1.21.2-0.8-1.0-0.90.9-0.71.50.2-0.41.5-1.30.7-0.4-0.50.50.8
Intermittent access intake escalation1.21.13.1-0.9-1.6-0.6-1.60.7-0.91.3-0.6-0.7-0.61.0-0.41.70.0-0.21.8-1.61.1-0.7-0.90.91.2
Intermittent access intake escalation 20.40.41.30.2-0.50.4-0.5-0.30.10.20.40.20.4-0.00.50.8-0.80.70.9-0.70.5-1.1-1.11.10.8
Intermitt. access day 1 inactive lever presses0.40.51.1-0.5-0.9-0.6-1.00.6-1.00.6-0.6-0.8-0.60.3-0.51.0-0.1-0.21.0-0.80.2-0.4-0.60.60.6
Intermitt. access day 15 inactive lever presses1.61.84.9-0.60.7-0.70.70.7-1.1-0.8-0.7-1.1-1.3-0.8-1.4-1.41.3-1.1-1.51.8-2.21.81.8-1.8-1.9
Intermitt. access escalation Index1.21.12.10.90.21.30.1-1.11.3-0.21.21.31.4-0.21.40.4-1.31.50.5-0.60.8-1.3-1.21.20.8
Intermittent access day 1 total infusions0.80.91.91.10.61.10.8-1.11.4-0.71.11.31.3-0.51.3-0.3-1.11.2-0.30.00.6-0.9-0.80.80.1
Intermittent access day 15 total infusions0.50.61.60.2-0.70.3-0.5-0.30.20.40.30.30.50.20.60.9-0.90.71.0-1.01.0-1.2-1.31.30.8
Intermittent access terminal intake (last 3 days)0.30.40.90.60.10.70.3-0.70.6-0.30.70.70.8-0.40.80.1-1.00.80.2-0.20.3-0.8-0.80.80.1
Intermittent access total infusions0.40.41.00.70.50.70.7-0.81.0-0.50.80.90.9-0.40.9-0.4-0.70.8-0.30.20.3-0.5-0.40.4-0.2
Intermittent access day 1 locomotion1.31.43.01.51.31.31.4-1.51.7-1.21.31.61.5-1.01.5-1.0-1.11.3-1.00.70.0-0.7-0.50.5-0.2
Intermittent access day 15 total locomotion0.70.82.50.1-0.60.3-0.6-0.30.60.70.30.60.70.70.81.1-0.60.71.1-1.31.6-1.1-1.11.11.3
Intermittent access total locomotion0.91.02.41.10.71.10.7-1.21.6-0.51.11.41.5-0.31.4-0.2-1.01.3-0.2-0.20.8-1.0-0.90.90.5
Intermittent access standard deviation0.70.71.8-0.8-0.4-0.9-0.40.9-1.30.1-0.8-1.2-1.4-0.2-1.3-0.10.7-1.0-0.10.5-1.10.90.8-0.8-1.0
Left kidney weight9.526.741.2-6.1-6.0-6.4-6.16.2-6.06.2-6.4-6.1-5.66.0-5.45.15.1-5.24.7-4.53.12.31.6-1.62.7
Right kidney weight6.919.430.6-5.5-5.1-5.4-5.25.3-5.05.3-5.2-5.1-4.95.1-4.74.24.7-4.43.8-3.52.32.31.8-1.82.1
Cocaine induced anxiety0.40.40.90.90.70.70.7-0.81.0-0.50.70.90.9-0.40.8-0.4-0.60.7-0.40.20.2-0.4-0.30.30.0
Post-drug Anxiety2.93.26.22.12.51.92.5-2.02.4-2.12.02.22.0-1.61.8-2.2-1.01.4-2.21.8-0.8-0.10.2-0.2-1.2
Baseline Anxiety2.93.17.31.42.51.52.5-1.51.8-2.21.51.51.1-1.81.0-2.6-0.20.7-2.72.4-1.80.91.1-1.1-2.0
Tail length5.918.032.0-5.3-5.1-5.0-5.24.8-3.95.6-4.6-4.2-4.15.7-3.94.54.6-3.84.1-4.13.31.91.4-1.42.7
Length with tail13.549.378.6-8.9-7.9-8.7-8.08.5-7.68.5-8.4-8.0-7.88.4-7.56.47.9-7.25.7-5.53.84.13.3-3.33.0
Length without tail9.220.233.8-5.6-4.3-5.8-4.35.7-5.34.6-5.7-5.5-5.64.7-5.52.95.5-5.42.3-2.11.03.83.3-3.30.5
Times rat made contact with spout0.60.71.6-1.0-1.1-0.8-1.20.8-0.21.2-0.4-0.5-0.61.2-0.51.10.6-0.71.0-1.11.00.10.0-0.00.6
Lifetime Intake0.40.40.90.60.70.60.9-0.70.8-0.80.70.70.6-0.70.6-0.9-0.40.5-0.90.7-0.40.00.2-0.2-0.8
Liver weight, left1.32.07.2-1.5-1.4-1.6-1.41.7-2.71.0-2.1-2.2-1.80.6-1.90.90.9-1.90.9-0.5-0.50.70.4-0.40.2
Liver weight, right3.45.79.0-2.8-2.9-2.8-2.92.8-3.02.8-3.0-2.9-2.62.6-2.62.42.1-2.52.3-2.01.21.00.6-0.61.2
Locomotor activity2.84.411.5-1.3-2.6-1.4-2.51.3-1.12.7-1.7-1.0-0.42.7-0.33.10.5-0.53.1-3.33.4-1.4-1.81.83.0
Locomotor testing distance1.01.73.9-0.9-1.7-0.9-1.60.9-1.21.5-1.2-1.0-0.61.3-0.51.90.2-0.32.0-1.91.6-1.0-1.21.21.6
Locomotor testing rearing0.10.10.50.3-0.10.30.0-0.2-0.2-0.20.2-0.00.1-0.50.20.2-0.70.40.4-0.2-0.1-0.7-0.70.70.1
Locomotion in novel chamber0.50.61.5-0.6-1.0-0.6-1.00.6-0.71.0-0.7-0.6-0.40.9-0.41.20.1-0.31.2-1.21.0-0.4-0.50.70.9
Locomotion in novel chamber post-restriction2.63.27.4-1.4-2.3-1.4-2.31.3-0.92.4-1.2-1.0-0.72.2-0.42.70.4-0.62.7-2.72.5-1.1-1.41.22.4
Fecal boli incidents, locomotor time 11.11.22.5-1.1-1.4-1.0-1.40.8-0.71.4-0.9-0.7-0.61.4-0.41.60.5-0.41.5-1.61.5-0.5-0.70.71.4
Change in fecal boli incidents, locomotor task0.80.72.10.40.90.40.9-0.20.1-0.90.30.1-0.0-0.9-0.2-1.20.2-0.2-1.31.4-1.41.01.1-1.1-1.3
Time >=10cm from walls, locomotor time 11.91.93.91.41.81.41.8-1.31.7-1.61.41.51.2-1.31.0-1.9-0.50.8-2.01.7-1.10.60.8-0.8-1.2
Bouts of movement, locomotor time 11.51.62.5-1.3-1.5-1.5-1.51.4-1.41.6-1.5-1.4-1.21.5-1.11.60.9-1.01.5-1.51.2-0.1-0.30.31.0
Total resting periods, locomotor time 11.21.42.2-1.2-1.4-1.4-1.41.3-1.21.5-1.4-1.2-1.01.4-0.91.50.8-0.91.4-1.41.2-0.2-0.40.41.0
Rest time, locomotor task time 10.50.50.9-1.0-0.7-0.9-0.70.9-0.70.8-0.8-0.8-0.80.9-0.70.50.9-0.90.4-0.40.30.60.5-0.50.1
Distance moved, locomotor task time 10.50.61.10.80.40.80.4-0.90.9-0.40.80.90.9-0.31.0-0.0-0.91.00.0-0.20.5-1.0-1.01.00.6
Vertical activity count, locomotor time 10.90.92.60.1-0.60.1-0.6-0.30.20.50.10.30.60.50.71.1-0.70.81.2-1.31.4-1.5-1.61.61.6
Time >=10cm from walls, locomotor time 21.11.24.1-0.9-0.1-0.8-0.00.9-0.30.4-0.8-0.6-0.90.7-1.0-0.61.8-1.4-0.90.7-0.52.02.0-2.0-0.8
Bouts of movement, locomotor time 21.61.73.1-1.4-1.5-1.7-1.51.5-1.51.5-1.7-1.5-1.31.4-1.21.50.9-1.11.4-1.41.1-0.0-0.30.31.0
Total resting periods, locomotor time 21.51.63.1-1.4-1.4-1.8-1.41.6-1.61.4-1.7-1.6-1.51.3-1.41.31.0-1.21.2-1.10.80.2-0.00.00.7
Rest time, locomotor task time 20.20.20.30.50.50.50.6-0.40.5-0.50.60.50.4-0.40.4-0.5-0.30.3-0.40.4-0.3-0.00.0-0.0-0.4
Distance moved, locomotor task time 20.10.10.3-0.3-0.5-0.2-0.50.1-0.20.4-0.1-0.2-0.20.3-0.10.5-0.00.00.6-0.50.4-0.4-0.40.40.6
Vertical activity count, locomotor time 22.02.24.2-1.6-2.0-1.5-2.01.3-1.51.8-1.4-1.4-1.11.5-0.92.00.6-0.82.0-1.91.5-0.6-0.80.81.7
Light reinforcement 10.71.33.51.31.11.41.3-1.51.9-0.91.31.71.7-0.61.6-0.7-0.91.3-0.70.30.5-0.7-0.60.60.2
Light reinforcement 20.10.10.30.40.30.40.4-0.40.3-0.40.40.30.3-0.50.3-0.3-0.60.4-0.20.3-0.3-0.3-0.20.2-0.2
Bone: marrow area0.81.73.7-1.4-1.9-1.4-1.81.4-1.91.5-1.5-1.7-1.41.1-1.31.70.5-0.71.7-1.40.6-0.2-0.40.40.7
Bone: maximum diameter1.42.54.2-2.0-1.7-2.0-1.72.0-2.01.7-2.0-1.9-1.91.7-1.81.31.8-1.71.1-1.00.51.10.9-0.90.3
Bone: maximum force2.13.66.5-2.3-2.3-2.2-2.22.2-2.32.3-2.5-2.2-1.92.2-1.91.91.8-1.81.8-1.71.30.70.5-0.51.0
Bone: maximum moment1.72.95.2-2.1-2.1-2.0-2.02.0-2.22.0-2.3-2.0-1.71.9-1.81.71.6-1.71.6-1.51.00.70.5-0.50.8
Mean time between licks in bursts1.31.83.11.81.51.71.4-1.61.1-1.61.31.41.6-1.71.5-1.1-1.61.6-0.90.9-0.7-1.0-0.90.9-0.3
Mean num. licks in bursts0.00.10.20.20.4-0.10.3-0.20.4-0.20.10.20.1-0.00.1-0.30.10.0-0.30.20.10.20.3-0.3-0.4
Cd content in liver3.63.98.42.10.82.40.7-2.32.1-1.22.62.32.4-1.52.60.1-2.92.90.4-0.40.5-2.7-2.62.60.7
Co content in liver0.30.41.2-0.5-1.0-0.0-0.90.3-0.60.50.0-0.4-0.30.1-0.11.0-0.40.51.1-0.70.1-0.7-0.70.70.5
Cu content in liver0.20.20.90.4-0.10.2-0.0-0.40.2-0.20.60.30.2-0.40.40.3-1.00.80.4-0.20.1-0.9-0.80.80.4
Fe content in liver1.51.84.1-1.2-1.8-0.9-1.81.1-0.71.9-1.0-0.7-0.61.8-0.42.00.5-0.71.9-2.01.9-0.5-0.70.71.6
K content in liver0.10.10.6-0.2-0.1-0.2-0.00.3-0.10.1-0.1-0.1-0.20.2-0.2-0.00.2-0.7-0.10.1-0.10.40.3-0.30.4
Mg content in liver0.40.40.9-0.9-0.7-0.6-0.70.7-0.40.7-0.5-0.5-0.60.7-0.60.50.6-0.90.4-0.40.30.50.4-0.40.6
Mn content in liver0.40.41.10.60.80.70.8-0.50.3-1.00.60.50.4-1.00.4-0.9-0.4-0.0-0.80.9-1.00.10.1-0.1-0.4
Na content in liver0.20.20.8-0.5-0.2-0.5-0.20.4-0.10.4-0.4-0.2-0.30.6-0.40.10.7-0.9-0.0-0.10.20.60.5-0.50.4
Rb content in liver1.62.03.21.71.61.81.7-1.71.4-1.71.51.61.6-1.71.4-1.4-1.51.5-1.31.2-0.9-0.7-0.50.5-0.7
Se content in liver0.40.51.7-0.9-0.3-0.6-0.40.60.50.8-0.1-0.1-0.51.1-0.40.01.3-0.7-0.2-0.10.41.11.2-1.2-0.0
Sr content in liver0.40.31.4-0.6-0.5-0.7-0.50.7-1.20.2-0.6-1.0-1.0-0.1-0.90.20.3-0.50.30.1-0.70.30.2-0.2-0.1
Zn content in liver2.93.26.1-2.2-2.1-2.1-2.12.2-2.51.8-2.0-2.4-2.31.5-2.11.61.6-2.11.5-1.10.21.00.7-0.70.4
Bone: minimum diameter0.00.00.1-0.1-0.20.1-0.10.0-0.10.0-0.00.00.0-0.00.10.1-0.2-0.20.2-0.10.0-0.1-0.10.10.3
Time in familiar zone, hab. session 10.60.62.60.10.60.40.60.0-0.6-0.9-0.1-0.3-0.3-1.0-0.4-1.00.1-0.4-1.01.3-1.60.80.9-0.9-1.1
Time in novel zone, hab. session 10.40.41.0-0.5-0.6-1.0-0.60.6-0.20.8-0.6-0.5-0.40.9-0.50.60.6-0.60.6-0.70.90.1-0.00.00.5
Total zone transitions, hab. session 11.82.65.61.91.11.71.3-2.02.4-1.12.12.22.1-1.02.2-0.5-1.72.1-0.40.10.7-1.7-1.61.60.5
Total locomotion distance, hab. session 10.40.61.31.00.90.61.0-0.91.2-0.80.81.00.9-0.61.0-0.7-0.60.9-0.60.40.1-0.5-0.40.4-0.1
Locomotion velocity, hab. session 11.21.73.61.71.31.41.5-1.61.9-1.21.61.81.6-1.01.7-0.9-1.21.8-0.80.50.2-1.1-0.90.9-0.0
Time in familiar zone, hab. session 20.50.61.8-0.40.40.20.40.2-0.1-0.4-0.1-0.2-0.4-0.3-0.5-0.90.7-0.4-1.01.0-1.11.21.4-1.4-1.1
Time in novel zone, hab. session 20.60.61.80.90.30.30.3-0.80.8-0.20.60.80.9-0.20.90.3-1.00.90.4-0.60.9-1.3-1.31.30.9
Total zone transitions, hab. session 20.20.31.0-0.1-0.5-0.1-0.5-0.10.10.5-0.00.20.30.50.30.7-0.10.10.7-0.80.9-0.6-0.70.71.0
Total locomotion distance, hab. session 20.20.30.70.60.10.40.3-0.50.4-0.20.30.50.6-0.10.70.1-0.60.50.2-0.30.6-0.8-0.80.80.6
Locomotion velocity, hab. session 20.20.30.80.60.10.30.2-0.50.4-0.10.20.50.6-0.10.70.2-0.60.60.2-0.40.6-0.9-0.90.90.6
Novel to familiar place preference ratio0.10.10.20.1-0.1-0.00.0-0.10.30.10.10.10.20.10.20.2-0.2-0.20.2-0.30.5-0.3-0.50.50.4
Novelty place preference0.10.20.40.50.10.30.3-0.40.5-0.20.40.40.5-0.20.5-0.0-0.50.00.0-0.10.3-0.5-0.60.60.4
Time in novel zone, NPP test0.10.10.20.2-0.00.10.2-0.20.3-0.10.20.20.3-0.00.30.1-0.3-0.00.1-0.20.4-0.4-0.50.50.4
Total zone transitions, NPP test0.20.30.80.2-0.20.1-0.2-0.30.40.30.10.40.50.40.50.5-0.20.80.5-0.60.9-0.7-0.70.70.8
Total locomotion distance, NPP test0.20.20.80.50.30.20.3-0.50.7-0.00.20.60.70.20.60.0-0.10.80.0-0.30.9-0.6-0.50.50.4
Locomotion velocity, NPP test0.40.62.00.6-0.00.20.0-0.50.70.30.20.60.80.40.80.5-0.41.00.6-0.91.4-1.1-1.11.10.9
Intraocular pressure1.52.23.9-1.3-1.8-1.6-1.81.6-1.91.8-2.0-1.7-1.31.6-1.31.81.0-1.31.8-1.71.30.1-0.20.21.3
Delta distance traveled before/after self-admin0.30.31.10.2-0.50.2-0.6-0.1-0.20.20.0-0.00.20.00.30.7-0.70.40.8-0.70.5-1.0-1.01.00.8
Delta ambulatory time before/after self-admin0.30.31.00.70.20.60.1-0.60.2-0.40.50.40.5-0.60.60.1-1.00.80.2-0.10.0-0.9-0.80.80.2
Parametrial fat weight0.51.02.3-0.7-0.0-1.0-0.11.0-1.50.0-1.3-1.4-1.20.0-1.4-0.41.1-1.5-0.50.7-1.11.31.1-1.1-0.5
Pavlov. Cond. lever latency2.32.95.0-2.2-2.0-1.9-2.02.1-2.11.9-2.0-2.1-2.11.8-2.01.61.7-1.81.4-1.20.50.90.7-0.70.6
Pavlov. Cond. magazine entry latency0.20.20.9-0.4-0.6-0.1-0.50.10.20.6-0.00.20.20.70.30.60.2-0.10.5-0.70.8-0.1-0.20.21.0
Pavlov. Cond. change in total contacts0.50.51.50.51.00.41.1-0.61.2-0.70.80.90.6-0.30.5-1.10.20.2-1.20.9-0.30.50.7-0.7-0.7
Pavlov. Cond. index score0.10.20.50.40.40.30.5-0.50.7-0.30.40.70.7-0.10.6-0.4-0.20.3-0.40.20.2-0.1-0.10.10.2
Pavlov. Cond. latency score0.40.51.50.80.80.70.8-0.91.2-0.60.91.11.0-0.41.0-0.6-0.40.6-0.60.40.1-0.2-0.20.20.1
Pavlov. Cond. lever contacts1.51.83.01.71.71.41.7-1.61.6-1.61.51.71.6-1.41.5-1.4-1.11.3-1.31.1-0.5-0.5-0.30.3-0.6
Pavlov. Cond. magazine entry number0.40.51.60.40.80.40.8-0.2-0.0-0.90.3-0.0-0.2-1.0-0.2-1.0-0.20.1-0.91.1-1.30.40.5-0.5-1.2
Pavlov. Cond. intertrial magazine entries1.11.33.31.30.91.30.9-1.31.5-1.11.81.31.0-1.21.3-0.6-1.61.8-0.40.5-0.3-1.2-0.90.9-0.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.30.40.10.5-0.40.5-0.30.30.50.4-0.10.4-0.40.00.1-0.50.3-0.00.10.2-0.2-0.0
Pavlov. Cond. response bias0.10.10.4-0.0-0.2-0.1-0.1-0.10.20.2-0.10.20.30.40.30.20.10.00.2-0.40.6-0.2-0.20.20.6
Pavlov. Cond. lever latency0.50.71.9-0.7-0.2-0.9-0.20.9-1.3-0.1-0.7-1.2-1.4-0.4-1.3-0.30.5-0.8-0.30.7-1.30.90.9-0.9-1.0
Pavlov. Cond. magazine entry latency1.11.23.51.41.51.21.6-1.31.9-1.11.21.61.6-0.71.4-1.2-0.50.4-1.20.80.1-0.2-0.20.20.0
Pavlov. Cond. change in total contacts0.60.91.90.80.10.70.2-0.91.10.10.71.01.30.21.20.5-0.80.90.5-0.81.4-1.2-1.31.31.3
Pavlov. Cond. index score1.01.33.31.40.91.20.9-1.41.8-0.51.21.71.8-0.21.7-0.2-1.01.1-0.2-0.31.1-1.1-1.11.10.9
Pavlov. Cond. latency score0.91.12.81.30.91.11.0-1.31.7-0.61.11.51.7-0.31.5-0.4-0.80.9-0.4-0.00.8-0.9-0.90.90.7
Pavlov. Cond. lever contacts0.40.51.50.70.40.70.5-0.91.2-0.10.71.11.20.11.1-0.0-0.40.7-0.0-0.31.0-0.6-0.60.60.6
Pavlov. Cond. magazine entry number1.31.63.8-1.7-1.4-1.4-1.41.6-2.01.1-1.5-1.8-1.90.8-1.70.81.2-1.00.8-0.4-0.50.90.9-0.9-0.5
Pavlov. Cond. intertrial magazine entries0.50.61.5-0.7-1.1-0.6-1.20.5-0.51.0-0.4-0.5-0.50.9-0.31.20.10.31.2-1.10.9-0.5-0.50.50.7
Pavlov. Cond. lever-magazine prob. diff.1.21.53.71.50.91.30.9-1.51.9-0.51.31.81.9-0.21.8-0.2-1.11.2-0.2-0.31.2-1.2-1.21.21.0
Pavlov. Cond. response bias1.11.54.11.30.71.30.8-1.42.0-0.41.41.81.9-0.11.8-0.2-1.01.2-0.1-0.41.2-1.2-1.11.11.0
Time in closed arm before self-admin1.61.93.4-1.2-1.8-1.6-1.81.4-1.81.5-1.6-1.6-1.31.2-1.21.80.5-0.91.8-1.61.0-0.4-0.60.61.1
Time in closed arm after self-admin1.81.84.5-0.7-1.7-0.7-1.60.6-0.71.6-0.7-0.5-0.11.40.02.1-0.20.02.1-2.11.9-1.3-1.51.62.1
Time in open arm before self-admin0.10.10.4-0.3-0.30.1-0.30.10.50.50.20.30.20.60.10.30.3-0.20.3-0.40.60.30.3-0.30.1
Time in open arm after self-admin0.40.40.90.40.80.60.8-0.40.5-0.70.50.40.3-0.70.2-0.9-0.10.1-0.90.9-0.80.40.5-0.8-0.9
Bone: periosteal estimation1.43.04.9-2.2-2.2-2.0-2.12.0-2.02.1-2.1-1.9-1.72.0-1.71.81.6-1.61.7-1.61.10.60.4-0.40.9
Bone: periosteal perimeter0.61.02.3-0.9-1.2-0.8-1.30.8-0.51.4-0.9-0.6-0.41.5-0.41.40.6-0.71.3-1.51.5-0.1-0.30.31.3
Bone: post-yield work0.20.20.4-0.5-0.6-0.6-0.60.5-0.60.6-0.5-0.5-0.50.5-0.40.60.2-0.40.6-0.50.30.0-0.00.0-0.1
Progressive ratio test 1 active lever presses0.50.50.9-0.8-1.0-0.9-0.80.8-0.80.9-0.9-0.8-0.70.9-0.70.80.5-0.70.8-0.80.70.20.1-0.10.3
Progressive ratio test 1 breakpoint0.50.50.9-0.8-1.0-0.9-0.80.9-0.80.9-0.9-0.8-0.70.9-0.70.80.6-0.80.8-0.80.70.30.2-0.20.3
Progressive ratio test 1 inactive lever presses1.21.43.3-0.8-1.6-1.0-1.60.9-1.01.4-0.9-0.9-0.61.1-0.51.8-0.0-0.31.8-1.71.4-0.8-1.01.01.4
Progressive ratio test 2 active lever presses1.41.54.2-0.7-1.6-0.8-1.50.6-0.51.6-0.8-0.5-0.21.5-0.11.9-0.1-0.21.9-2.02.0-0.9-1.11.11.6
Progressive ratio test 2 breakpoint1.11.24.2-0.2-1.2-0.3-1.20.20.01.2-0.30.00.31.20.41.7-0.50.31.7-1.92.0-1.2-1.31.31.5
Progressive ratio test 2 inactive lever presses2.83.27.9-1.4-2.5-1.4-2.51.4-1.72.1-1.4-1.5-1.01.7-0.82.7-0.0-0.52.8-2.61.9-1.2-1.51.52.0
Incentive Sensitization - Responses1.11.12.40.7-0.30.7-0.3-0.80.90.30.70.91.10.21.20.9-1.31.11.0-1.11.4-1.5-1.51.51.2
Incentive Sensitization - Breakpoint1.21.22.80.7-0.30.8-0.4-0.80.90.30.81.01.20.21.31.0-1.41.21.1-1.21.5-1.7-1.71.71.3
Sum of active levers in priming session hrs 5-60.70.72.50.21.10.51.1-0.30.6-0.90.40.40.3-0.70.2-1.50.6-0.0-1.61.5-1.20.60.6-0.9-0.7
Progressive ratio0.60.71.60.60.90.61.0-0.60.5-1.10.70.40.2-1.10.1-1.2-0.30.2-1.21.3-1.30.70.8-0.7-1.2
Food seeking constrained by brief footshock0.91.13.41.11.01.10.9-1.00.4-1.51.20.60.5-1.80.6-1.0-1.41.0-0.81.2-1.6-0.5-0.40.5-1.0
Seeking ratio, punishment vs. effort0.30.40.8-0.5-0.7-0.6-0.80.6-0.80.6-0.6-0.6-0.50.5-0.40.90.0-0.20.9-0.70.4-0.5-0.60.60.6
Retroperitoneal fat weight1.13.710.90.82.50.62.4-0.60.8-2.00.20.60.3-1.4-0.2-3.11.1-1.0-3.33.0-2.32.42.6-2.6-2.4
Reaction time number correct0.70.92.7-0.2-1.1-0.5-1.10.4-1.00.8-0.6-0.6-0.20.5-0.11.5-0.60.21.6-1.41.0-1.3-1.41.41.1
Reaction time mean minus median0.40.53.70.40.20.0-0.0-0.30.90.7-0.30.71.01.20.70.50.40.30.3-1.01.9-0.4-0.40.41.2
Reaction time mean minus median AUC0.91.22.91.40.70.90.4-1.11.1-0.10.41.21.70.11.50.3-1.01.40.4-0.81.6-1.4-1.41.41.1
Reaction time num false alarms0.81.12.41.10.41.00.4-1.11.6-0.01.01.41.50.21.50.3-0.81.30.4-0.81.5-1.3-1.21.21.1
Reaction time num false alarms AUC0.50.71.80.80.20.60.2-0.81.10.10.71.01.10.31.10.4-0.61.00.5-0.81.4-1.1-1.11.11.0
Reaction time trials correct on left0.70.92.7-0.2-1.1-0.5-1.10.4-1.00.8-0.6-0.6-0.20.5-0.11.5-0.60.21.6-1.41.0-1.3-1.41.41.1
Reaction time trials on left0.60.92.6-0.2-1.1-0.5-1.10.3-0.90.8-0.6-0.6-0.20.5-0.11.5-0.60.21.6-1.41.0-1.3-1.41.41.1
Reaction time mean1.72.35.52.02.31.72.0-1.82.0-1.71.31.92.0-1.21.6-1.8-0.81.3-1.81.3-0.30.00.3-0.3-0.9
Reaction time mean AUC1.92.65.62.22.41.92.0-2.02.1-1.71.42.12.1-1.21.8-1.7-1.01.5-1.71.2-0.2-0.30.0-0.0-0.8
Median of all reaction times2.83.88.02.42.82.22.6-2.22.2-2.31.72.22.1-1.91.7-2.5-1.11.5-2.42.1-1.10.20.5-0.5-1.6
Reaction time omissions0.50.71.81.11.21.11.0-1.11.1-0.70.61.21.3-0.41.1-0.7-0.50.9-0.70.40.3-0.4-0.30.3-0.0
Reaction time false alarm rate0.30.52.10.80.60.70.6-0.81.4-0.20.91.11.00.21.0-0.2-0.20.7-0.2-0.20.9-0.4-0.30.30.5
Reaction time premature initiation rate0.10.10.7-0.1-0.2-0.1-0.1-0.00.50.40.10.30.30.60.20.30.20.00.3-0.50.9-0.1-0.10.10.6
Reaction time premature initiations0.30.41.3-0.2-0.6-0.3-0.50.1-0.00.7-0.3-0.10.20.70.10.9-0.00.10.9-1.01.2-0.6-0.70.71.0
Std. dev. reaction times0.30.51.51.11.10.60.8-0.81.0-0.30.11.01.20.20.9-0.5-0.10.6-0.60.00.9-0.2-0.10.10.2
Reaction time trials completed0.60.92.6-0.2-1.1-0.5-1.10.3-0.90.8-0.6-0.6-0.20.5-0.11.5-0.60.21.6-1.41.0-1.3-1.41.41.1
Reaction time trials AUC0.60.92.50.0-0.9-0.2-0.90.1-0.70.6-0.3-0.30.10.30.21.4-0.80.51.5-1.31.0-1.5-1.61.61.2
Run reversals in cocaine runway, females0.30.30.70.70.70.50.7-0.60.3-0.80.40.40.4-0.80.4-0.6-0.60.6-0.60.6-0.6-0.3-0.30.1-0.4
Run reversals in cocaine runway, males1.21.13.70.5-0.40.6-0.4-0.70.60.20.90.70.8-0.11.11.0-1.51.21.2-1.11.0-1.9-1.91.71.3
Latency to leave start box in cocaine runway0.10.10.30.20.50.20.4-0.20.4-0.20.20.30.3-0.10.2-0.50.30.0-0.60.4-0.20.30.4-0.5-0.2
Latency to leave start box in cocaine runway, F0.70.81.9-0.8-0.0-0.9-0.10.9-1.00.1-1.0-1.0-1.00.2-1.2-0.51.3-1.1-0.60.7-0.81.21.2-1.4-0.7
Latency to leave start box in cocaine runway, M2.32.24.31.40.61.60.5-1.71.9-0.41.71.92.0-0.32.10.3-1.71.90.5-0.71.3-2.0-1.91.91.2
Std. dev. time between licks in bursts0.50.62.0-0.0-0.70.1-0.7-0.0-0.00.7-0.20.20.40.60.51.1-0.40.41.1-1.21.3-1.1-1.21.21.4
Total sessions with >9 infusions0.00.00.0-0.1-0.1-0.10.00.10.10.1-0.10.0-0.00.2-0.0-0.00.2-0.1-0.1-0.00.20.20.2-0.2-0.2
Short access day 1 total inactive lever presses0.10.10.4-0.4-0.3-0.4-0.20.5-0.60.2-0.4-0.6-0.50.1-0.50.10.3-0.50.10.0-0.30.20.1-0.1-0.0
Short access day 10 total inactive lever presses2.12.45.4-2.0-1.6-1.8-1.72.0-2.31.3-1.9-2.2-2.11.0-2.11.01.6-1.80.9-0.6-0.31.00.8-0.80.2
Short access day 1 total infusions1.61.74.60.81.50.91.6-0.70.5-1.70.90.60.3-1.70.2-2.0-0.30.2-1.92.1-2.10.81.0-1.0-2.1
Short access day 10 total infusions0.80.91.41.21.01.01.1-1.11.0-1.21.11.01.0-1.11.0-0.9-1.11.1-0.80.8-0.5-0.5-0.40.4-0.8
Short access total infusions1.11.23.80.31.20.31.3-0.30.4-1.20.30.2-0.0-1.0-0.2-1.70.4-0.2-1.81.8-1.61.21.4-1.4-2.0
Short access day 1 locomotion0.80.82.11.01.20.91.2-1.01.5-0.91.01.31.1-0.61.0-1.0-0.40.7-1.10.7-0.1-0.00.1-0.1-0.5
Short access day 10 total locomotion0.30.30.80.50.80.30.8-0.40.2-0.90.40.20.2-0.90.1-0.9-0.30.3-0.80.9-0.90.10.2-0.2-0.6
Short access total locomotion0.90.92.50.81.40.61.4-0.70.9-1.20.60.70.5-1.00.4-1.5-0.10.4-1.61.4-1.00.50.7-0.7-1.1
One hour access (0.3 mA shock)1.72.05.80.7-0.90.6-0.9-0.70.40.50.60.71.00.21.21.7-1.91.41.9-1.81.8-2.3-2.42.41.7
Compulsive drug intake2.82.85.12.32.02.01.8-2.11.7-2.02.01.91.8-2.11.8-1.4-2.11.8-1.21.2-0.8-1.1-1.01.0-0.6
One hour access (shock baseline)1.72.05.2-0.8-1.9-0.7-1.70.6-0.51.7-0.7-0.4-0.11.60.02.2-0.20.12.2-2.32.2-1.2-1.41.41.9
Social response proportion4.34.79.9-2.4-2.3-2.6-2.32.4-1.92.9-2.8-2.1-1.83.1-1.92.22.5-2.11.9-2.22.30.80.5-0.51.7
Social responses1.92.55.7-1.3-2.0-1.0-1.91.1-1.02.1-1.4-0.9-0.42.1-0.42.30.6-0.62.3-2.42.3-0.9-1.11.12.2
Social time2.22.95.52.31.61.91.7-2.22.1-1.51.72.12.4-1.32.2-0.9-1.82.2-0.80.40.4-1.7-1.51.50.3
Soleus weight1.13.16.2-2.1-2.5-2.0-2.42.0-1.82.3-1.8-1.8-1.72.1-1.52.21.4-1.12.1-2.01.40.1-0.00.01.1
Bone: stiffness0.61.02.8-0.8-1.3-0.6-1.20.7-0.51.4-0.9-0.4-0.21.5-0.21.40.5-0.21.4-1.61.7-0.4-0.50.51.4
Tibialis anterior weight5.318.029.6-5.4-4.9-5.4-4.95.1-4.25.3-5.0-4.6-4.65.4-4.44.04.9-3.93.5-3.52.82.31.9-1.81.7
Time to tail flick, vehicle, before self-admin0.60.61.60.61.00.61.2-0.71.2-0.80.61.00.9-0.40.8-1.20.20.5-1.20.9-0.20.10.1-0.2-0.1
Time to tail flick, vehicle, after self-admin0.60.61.40.80.40.70.3-0.81.0-0.20.71.01.1-0.11.10.0-0.81.00.1-0.30.7-1.1-1.20.90.8
Time to tail flick, test, before self-admin0.50.50.9-0.8-0.7-0.7-1.00.8-0.80.9-0.7-0.8-0.90.8-0.80.70.8-0.80.7-0.60.30.40.3-0.50.2
Time to tail flick, test, after self-admin0.50.61.7-0.60.3-0.50.20.5-0.2-0.0-0.4-0.4-0.60.2-0.7-0.71.3-0.9-0.80.8-0.81.31.3-1.2-0.7
Delta time to tail flick, vehicle, before/after SA0.60.61.70.90.20.80.1-0.90.5-0.40.80.70.8-0.50.90.2-1.31.00.4-0.30.3-1.2-1.11.00.3
Delta time to tail flick, test, before/after SA0.40.41.00.20.70.10.8-0.20.1-0.70.20.1-0.0-0.6-0.1-1.00.2-0.0-1.01.0-1.00.60.7-0.4-0.9
Tibia length4.011.220.2-4.5-3.2-4.2-3.14.2-3.83.3-3.9-4.1-4.23.3-4.21.94.4-3.81.5-1.20.33.12.8-2.8-0.1
Ambulatory time before self-admin0.30.31.40.40.10.30.2-0.51.00.20.40.80.80.50.80.3-0.30.50.3-0.61.2-0.5-0.50.60.7
Ambulatory time after self-admin0.30.30.70.60.10.60.1-0.60.8-0.00.60.70.80.00.70.3-0.70.60.3-0.50.8-0.6-0.50.10.3
Bone: tissue strength0.20.21.1-0.10.0-0.20.00.3-0.9-0.4-0.3-0.6-0.7-0.6-0.6-0.2-0.2-0.6-0.20.5-1.10.30.2-0.2-0.7
Total heroin consumption4.04.610.02.62.22.72.0-2.83.2-1.92.83.02.9-1.72.8-1.4-2.42.6-1.20.80.2-1.5-1.11.2-0.1
Bone: trabecular number3.45.48.7-3.0-2.6-2.9-2.72.9-2.92.6-2.8-2.9-2.92.3-2.82.02.4-2.41.8-1.50.61.41.1-1.10.5
Bone: trabecular spacing2.73.55.92.42.32.42.2-2.32.2-2.32.32.22.1-2.22.0-1.8-1.91.5-1.71.6-1.1-0.8-0.60.6-0.7
Bone: trabecular thickness4.04.87.5-2.7-2.4-2.7-2.52.7-2.72.5-2.7-2.7-2.62.3-2.51.92.3-2.21.7-1.50.81.31.1-1.10.6
Bone: trabecular tissue density0.20.32.10.20.3-0.10.3-0.00.60.4-0.60.40.71.00.3-0.00.7-0.5-0.2-0.41.40.30.2-0.21.0
Water consumed over 24 hours2.32.85.1-2.0-2.3-2.0-2.21.9-2.02.0-1.9-2.0-1.81.7-1.72.01.1-1.51.9-1.71.00.2-0.10.11.0
Number of responses in last shaping day0.10.10.2-0.2-0.3-0.4-0.30.3-0.50.3-0.4-0.4-0.40.2-0.30.3-0.1-0.20.4-0.30.1-0.1-0.20.20.1