Stard13

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability Stard13 0.09 0.06 6.2e-05 0.05 0.06 0.07 0.06 5.5e-05 1.0e-05 3.3e-06 3.3e-05
2 IC gene expression Stard13 0.27 0.11 1.4e-08 0.16 0.19 0.18 0.19 2.1e-07 2.6e-08 7.2e-08 2.6e-08
3 pVTA gene expression Stard13 0.2 0.1 5.6e-13 0.18 0.16 0.17 0.17 1.0e-14 3.0e-13 1.5e-13 1.5e-13
4 PL gene expression Stard13 0.1 0.06 7.8e-08 0.06 0.06 0.06 0.06 1.2e-07 1.4e-07 8.4e-07 3.2e-07
5 BLA gene expression Stard13 0.16 0.09 2.0e-05 0.12 0.08 0.1 0.11 8.7e-07 3.4e-05 4.6e-06 2.4e-06
6 BLA alternative TSS XM_006248749.5 0.08 0.05 4.9e-03 0.06 0.01 0.04 0.04 3.7e-04 1.0e-01 5.3e-03 4.3e-03
7 Adipose gene expression Stard13 0.3 0.13 0.0e+00 0.23 0.23 0.23 0.23 3.8e-25 3.5e-25 3.7e-25 2.4e-25
8 Brain gene expression Stard13 0.18 0.09 7.5e-12 0.09 0.12 0.1 0.11 5.6e-09 4.5e-11 1.1e-09 1.9e-10
9 pVTA alternative TSS XM_006248749.5 0.05 0.04 8.0e-04 0.03 0.04 0.04 0.03 1.9e-03 8.3e-04 7.2e-04 1.1e-03
10 PL mRNA stability Stard13 0.08 0.05 2.4e-06 0.04 0.05 0.04 0.05 2.2e-05 3.4e-06 2.2e-05 2.1e-06
11 NAcc alternative TSS NM_001109060.1 0.04 0.03 8.7e-03 0 0.01 0.01 0.01 7.4e-02 1.4e-02 2.5e-02 2.4e-02
12 Brain mRNA stability Stard13 0.09 0.05 2.7e-08 0.1 0.08 0.1 0.09 2.8e-09 5.3e-08 1.6e-09 1.6e-08
13 NAcc gene expression Stard13 0.21 0.09 0.0e+00 0.15 0.21 0.21 0.21 6.0e-22 1.7e-31 6.2e-31 5.3e-31
14 Liver gene expression Stard13 0.03 0.02 9.3e-03 -0 -0 -0 -0 9.5e-01 5.2e-01 7.8e-01 8.8e-01
15 Adipose intron excision ratio chr12_5717659_5794781 0.03 0.02 9.6e-03 0 0.01 0.01 0 2.6e-01 2.5e-02 3.2e-02 1.2e-01
16 NAcc mRNA stability Stard13 0.03 0.03 7.4e-03 0.01 0.01 0 0 1.9e-02 1.1e-02 1.0e-01 6.4e-02
17 Adipose alternative TSS XM_006248749.5 0.03 0.02 8.4e-03 0 0.01 0 0 1.8e-01 3.8e-02 9.6e-02 9.4e-02
18 BLA mRNA stability Stard13 0.09 0.06 5.5e-04 0.06 0.06 0.05 0.05 5.5e-04 4.4e-04 1.8e-03 1.4e-03
19 NAcc alternative TSS XM_006248749.5 0.04 0.02 4.2e-05 0.02 0.03 0.02 0.02 8.3e-04 7.3e-05 5.9e-04 5.6e-04
20 IC alternative TSS XM_017598426.3 0.18 0.17 3.4e-03 0.07 0.05 0.07 0.07 6.6e-04 4.8e-03 5.2e-04 6.0e-04
21 PL alternative TSS XM_006248749.5 0.04 0.03 5.3e-05 0.05 0.04 0.04 0.04 9.0e-06 3.3e-05 2.8e-05 1.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density3.25.59.43.12.62.62.62.5-2.52.03.0-1.81.82.21.92.93.0-3.01.8-1.31.2-2.7-0.4-2.0
Area under the delay curve1.72.05.8-1.7-1.2-1.0-1.0-1.01.0-0.3-2.10.0-0.1-1.2-0.1-2.3-2.32.3-0.7-0.30.52.4-0.72.2
BMI with tail0.93.18.83.01.72.22.22.0-2.01.71.6-1.91.80.92.51.31.8-1.60.8-1.81.7-1.0-0.1-0.6
BMI without tail2.68.016.83.33.13.43.43.3-3.33.42.1-3.53.52.24.11.61.7-1.62.4-3.43.4-0.8-1.80.5
Body weight9.541.471.08.47.37.57.47.5-7.57.85.6-7.47.35.38.34.44.8-4.55.4-7.37.1-2.9-4.1-0.3
Weight adjusted by age0.71.02.81.71.20.80.81.1-1.10.81.4-0.60.50.90.71.31.4-1.40.7-0.40.3-1.3-0.3-1.0
Bone surface3.05.510.93.32.72.72.72.7-2.72.52.5-2.32.32.02.72.22.5-2.41.8-2.12.0-1.9-1.0-1.0
Bone volume1.62.86.62.61.81.91.91.8-1.81.52.1-1.31.31.21.71.92.2-2.11.0-1.11.0-1.8-0.1-1.4
Breakpoint value in progressive ratio session0.40.41.5-0.2-0.10.40.40.2-0.20.3-0.6-0.60.70.00.5-0.8-1.01.00.3-0.80.91.1-0.61.2
Number of licking bursts0.81.32.71.31.41.11.11.3-1.30.81.6-0.60.61.30.61.61.6-1.61.0-0.40.3-1.6-0.1-1.2
Context. condit. distance diff. score2.93.66.21.52.02.12.12.1-2.12.51.0-2.52.41.82.30.70.4-0.42.1-2.52.5-0.0-2.21.0
Locomotion velocity, session 10.50.61.3-1.1-0.7-0.8-0.8-0.70.7-0.4-1.00.4-0.4-0.5-0.5-1.0-1.21.1-0.40.2-0.21.0-0.30.9
Locomotion distance, session 11.01.23.1-1.7-1.2-1.2-1.2-1.21.2-1.2-1.21.0-1.0-0.8-1.4-1.0-1.21.2-0.71.0-0.90.90.30.5
Locomotion velocity, session 20.20.20.8-0.8-0.4-0.4-0.4-0.30.3-0.1-0.70.0-0.1-0.1-0.2-0.7-0.90.80.0-0.10.10.8-0.50.8
Locomotion distance, session 20.50.73.5-1.9-0.7-0.8-0.8-0.80.8-0.8-0.70.7-0.60.1-1.5-0.5-1.00.90.10.7-0.70.5-0.30.4
Locomotion velocity, session 30.20.20.50.20.40.40.40.4-0.40.60.0-0.60.60.40.5-0.1-0.20.20.5-0.70.70.3-0.70.5
Locomotion distance, session 30.10.20.5-0.10.10.10.10.1-0.1-0.20.50.2-0.20.3-0.50.60.5-0.50.20.4-0.5-0.70.3-0.7
Stereotopy head waving bouts, day 32.73.15.12.32.11.91.92.1-2.11.82.1-1.61.51.71.81.91.9-1.91.6-1.41.3-1.7-0.7-0.9
Stereotopy head waving duration, day 30.10.10.20.40.1-0.1-0.10.1-0.1-0.10.30.2-0.2-0.10.10.30.5-0.4-0.20.2-0.2-0.40.4-0.5
Locomotion velocity, session 71.51.64.5-1.3-1.1-1.0-1.0-1.01.0-0.3-1.90.2-0.2-1.1-0.2-2.0-2.12.1-0.7-0.20.32.1-0.52.0
Locomotion distance, session 70.50.72.4-1.1-0.3-0.2-0.2-0.20.20.2-0.9-0.40.40.1-0.1-1.0-1.41.30.4-0.50.61.3-1.11.6
Stereotopy head waving bouts, day 70.10.10.5-0.7-0.4-0.4-0.4-0.40.4-0.3-0.40.3-0.2-0.1-0.5-0.4-0.60.5-0.00.2-0.20.4-0.10.4
Stereotopy head waving duration, day 70.50.61.0-1.0-0.9-0.9-0.9-0.90.9-0.9-0.90.8-0.7-0.7-0.9-0.8-0.80.8-0.60.7-0.60.70.40.4
Locomotion velocity, session 80.20.30.80.00.10.20.20.2-0.20.5-0.4-0.60.5-0.00.6-0.6-0.60.60.2-0.70.80.7-0.70.9
Locomotion distance, session 80.91.32.50.71.11.21.21.2-1.21.50.4-1.61.51.01.40.2-0.00.01.2-1.61.60.2-1.50.8
Degree of sensitization distance1.01.02.8-1.4-0.9-0.9-0.9-0.90.9-0.5-1.40.3-0.3-0.7-0.5-1.5-1.71.6-0.40.10.01.5-0.51.5
Degree of sensitization stereotypy0.50.51.1-1.0-0.8-0.8-0.8-0.80.8-0.7-0.90.6-0.5-0.6-0.7-0.9-1.00.9-0.50.4-0.40.80.10.6
Conditioned locomotion0.20.20.70.30.0-0.0-0.00.0-0.0-0.30.50.4-0.4-0.0-0.20.60.7-0.7-0.20.5-0.5-0.70.6-0.9
Cocaine response after cond. corrected0.60.72.70.9-0.7-0.6-0.6-0.70.7-0.7-0.40.9-1.0-1.50.4-0.30.5-0.3-1.70.7-0.70.01.6-0.8
Cocaine response after cond. not corrected0.40.51.90.6-0.7-0.6-0.6-0.60.6-0.4-0.70.6-0.6-1.40.5-0.7-0.10.3-1.40.3-0.20.50.9-0.1
Cocaine response before conditioning0.60.82.6-0.70.40.40.40.4-0.40.8-0.3-1.01.00.80.3-0.5-1.00.91.1-1.11.10.9-1.61.4
Saline control response4.45.910.71.72.92.92.92.8-2.82.52.6-2.62.63.31.62.41.7-1.93.2-2.12.0-1.8-2.1-0.4
Bone: connectivity density5.38.312.53.53.33.43.43.3-3.33.03.3-2.82.82.92.93.02.9-2.92.7-2.42.3-2.5-1.4-1.3
Bone: cortical apparent density0.60.81.7-0.8-1.0-0.9-0.9-0.90.9-0.5-1.30.5-0.5-1.1-0.2-1.3-1.21.2-0.90.2-0.21.20.10.9
Bone: cortical area1.52.35.21.31.41.51.51.5-1.52.00.3-2.12.01.02.2-0.1-0.10.21.3-2.22.30.6-1.81.3
Bone: cortical porosity0.10.10.30.30.30.40.40.3-0.30.10.5-0.10.20.4-0.20.60.5-0.60.30.0-0.0-0.60.1-0.5
Bone: cortical porosity0.00.00.2-0.4-0.1-0.0-0.0-0.10.1-0.2-0.00.1-0.10.1-0.50.0-0.20.10.10.2-0.2-0.00.00.0
Bone: cortical thickness1.22.14.21.41.41.61.61.5-1.51.90.6-1.91.91.02.10.20.2-0.11.2-2.02.10.3-1.61.0
Bone: cortical thickness1.51.83.11.01.41.51.51.4-1.41.70.8-1.71.71.41.50.60.3-0.31.6-1.71.7-0.1-1.60.7
Bone: cortical tissue density0.60.81.5-0.8-1.0-0.9-0.9-0.90.9-0.6-1.20.6-0.6-1.1-0.3-1.2-1.11.1-0.90.4-0.31.10.20.8
Condit. Reinf. active minus inactive responses1.01.11.8-1.1-1.3-1.2-1.2-1.21.2-0.9-1.40.8-0.8-1.2-0.7-1.3-1.21.3-1.10.6-0.51.20.40.8
Condit. Reinf. active-inactive response ratio0.70.81.7-0.7-1.0-0.8-0.8-0.90.9-0.6-1.30.4-0.4-1.1-0.2-1.3-1.21.2-0.90.2-0.11.30.21.0
Condit. Reinf. active responses0.50.61.5-1.2-0.8-0.8-0.8-0.70.7-0.6-1.00.4-0.4-0.4-0.7-0.9-1.11.1-0.30.3-0.20.9-0.10.8
Condit. Reinf. inactive responses0.30.32.1-1.5-0.4-0.5-0.5-0.40.4-0.4-0.50.2-0.30.2-0.9-0.4-0.90.80.30.3-0.30.5-0.50.6
Incentive salience index mean0.60.71.6-1.3-1.0-0.9-0.9-0.90.9-0.8-1.10.6-0.6-0.7-0.9-1.0-1.11.1-0.60.5-0.50.90.20.7
Condit. Reinf. lever presses0.20.31.2-1.1-0.6-0.5-0.5-0.60.6-0.6-0.60.3-0.3-0.2-0.9-0.6-0.80.7-0.10.4-0.30.5-0.00.5
Condit. Reinf. active minus inactive responses1.62.14.70.41.21.31.31.2-1.21.80.1-2.01.91.31.7-0.2-0.70.61.6-2.12.10.8-2.21.6
Condit. Reinf. active-inactive response ratio0.91.12.9-0.20.60.60.60.6-0.61.2-0.4-1.31.20.71.1-0.6-1.00.91.0-1.41.51.0-1.71.6
Condit. Reinf. active responses1.82.55.70.41.31.51.51.4-1.42.00.1-2.22.11.41.9-0.2-0.70.61.8-2.32.30.9-2.41.8
Condit. Reinf. inactive responses0.50.61.20.40.81.01.00.8-0.81.00.5-1.11.10.90.70.30.1-0.21.0-1.01.0-0.1-1.00.4
Condit. Reinf. lever presses0.20.30.9-0.20.30.30.30.3-0.30.6-0.2-0.60.60.40.6-0.3-0.60.50.6-0.70.80.6-1.00.8
Condit. Reinf. lever reinforcers received1.42.05.2-0.01.01.21.21.1-1.11.7-0.1-1.91.91.21.5-0.4-0.90.91.6-2.02.01.0-2.31.9
Conditioned reinforcement - actives2.44.16.82.02.52.22.22.3-2.32.61.9-2.22.32.31.51.61.3-1.32.3-2.22.2-1.0-2.20.0
Conditioned reinforcement - inactives0.60.91.90.91.00.90.90.9-0.90.51.3-0.30.51.1-0.71.41.3-1.30.9-0.30.2-1.30.1-1.1
Conditioned locomotion2.63.46.11.52.22.12.12.2-2.22.51.5-2.22.32.11.51.20.8-0.92.3-2.22.1-0.6-1.80.4
Patch foraging indifference point 0 sec0.71.34.70.80.40.30.30.2-0.2-0.41.50.6-0.60.6-0.41.81.9-1.90.11.0-1.1-2.11.1-2.2
Patch foraging indifference point AUC1.11.62.31.21.51.51.51.4-1.41.21.5-1.21.21.50.91.41.3-1.31.4-1.00.9-1.2-0.7-0.6
Delay disc. indifference point, 0s delay1.51.64.80.4-0.3-0.2-0.2-0.30.31.1-1.6-0.90.6-1.42.0-2.0-1.51.7-0.9-1.21.32.2-1.02.1
Delay disc. indifference point, 16s delay0.50.61.5-1.1-0.7-0.8-0.8-0.20.2-0.2-1.00.1-0.1-0.40.1-1.1-1.21.2-0.1-0.20.31.2-0.81.2
Delay disc. indifference point, 2s delay3.74.110.2-2.0-2.0-1.8-1.8-1.91.9-1.0-3.00.7-0.8-2.2-0.4-3.2-3.03.1-1.70.10.13.2-0.12.5
Delay disc. indifference point, 24s delay0.80.91.7-1.2-1.0-1.1-1.1-0.90.9-0.6-1.30.6-0.6-0.8-0.5-1.2-1.31.3-0.70.3-0.31.20.01.1
Delay disc. indifference point, 4s delay1.71.84.8-1.3-1.3-1.1-1.1-1.21.2-0.5-2.00.2-0.4-1.5-0.3-2.1-2.02.1-1.1-0.10.22.20.01.9
Delay disc. indifference point, 8s delay0.50.61.8-1.3-0.5-0.1-0.1-0.50.5-0.2-1.0-0.30.3-0.1-0.5-1.1-1.31.30.1-0.30.41.2-0.61.3
Indifference point function ln k0.10.20.6-0.10.40.30.30.4-0.40.30.5-0.20.20.8-0.00.50.2-0.30.7-0.0-0.0-0.5-0.6-0.2
Indifference point function log k0.10.20.6-0.10.40.30.30.4-0.40.30.5-0.20.20.8-0.00.50.2-0.30.7-0.0-0.0-0.5-0.6-0.2
Patch foraging total patch changes 0 sec0.91.76.20.80.50.30.30.3-0.3-0.41.80.7-0.70.7-0.52.12.1-2.20.21.1-1.3-2.41.1-2.5
Patch foraging total patch changes 12 sec0.70.92.91.30.70.60.60.6-0.60.11.40.0-0.10.60.21.51.7-1.70.20.3-0.4-1.70.6-1.6
Patch foraging total patch changes 18 sec1.11.65.50.80.60.60.60.5-0.5-0.21.80.3-0.40.7-0.32.02.1-2.20.20.8-0.9-2.31.2-2.3
Patch foraging total patch changes 24 sec0.71.34.00.20.90.70.70.8-0.80.21.7-0.10.01.5-0.41.91.5-1.71.20.4-0.6-2.00.1-1.7
Patch foraging total patch changes 6 sec1.01.65.01.10.90.70.70.8-0.80.11.90.1-0.11.0-0.12.12.1-2.10.60.5-0.6-2.20.7-2.1
Patch foraging time to switch 0 sec2.65.414.0-0.9-2.7-2.7-2.7-2.52.5-2.0-2.92.1-2.2-3.7-0.5-2.9-1.92.2-3.51.4-1.22.52.01.1
Patch foraging water rate 0 sec3.57.414.41.83.23.03.03.0-3.02.33.6-2.22.13.80.93.62.9-3.13.4-1.31.1-3.3-1.4-2.0
Patch foraging water rate 12 sec0.61.23.50.21.21.51.51.2-1.20.91.3-1.11.11.90.31.30.7-0.91.8-0.60.5-1.1-0.8-0.4
Patch foraging water rate 18 sec0.30.51.7-1.00.50.50.50.4-0.40.7-0.0-0.80.81.10.1-0.1-0.70.61.3-0.60.60.4-1.30.9
Patch foraging water rate 24 sec3.04.27.71.32.42.52.52.4-2.42.12.3-2.22.22.81.32.11.6-1.72.7-1.71.6-1.7-1.4-0.5
Patch foraging water rate 6 sec1.01.53.20.61.51.41.41.3-1.31.31.5-1.01.01.80.71.51.0-1.11.7-0.60.6-1.2-0.9-0.7
Seeking ratio, delayed vs. immediate footshock1.62.04.9-0.6-1.1-1.4-1.4-1.41.4-1.5-0.32.1-2.1-1.3-1.20.10.4-0.4-1.62.2-2.2-0.61.6-1.6
Distance traveled before self-admin0.60.81.7-1.2-1.2-0.7-0.7-0.70.7-0.9-1.30.4-0.6-0.9-0.7-1.3-1.31.3-0.70.4-0.31.20.21.1
Distance traveled after self-admin0.20.21.2-0.9-0.20.10.1-0.10.1-0.3-0.3-0.10.10.4-1.1-0.3-0.60.50.5-0.10.10.4-0.40.8
Extensor digitorum longus weight4.718.327.54.64.95.15.14.9-4.95.23.5-5.25.14.25.02.82.5-2.44.4-4.94.8-1.7-3.80.4
Bone: elastic displacement0.30.40.50.60.70.70.70.7-0.70.60.7-0.50.60.70.40.70.6-0.60.6-0.50.4-0.6-0.3-0.3
Bone: elastic work3.54.56.52.42.52.62.62.5-2.52.32.3-2.22.22.22.02.01.9-1.92.1-2.01.9-1.6-1.3-0.6
Bone: endosteal estimation1.22.64.61.71.91.81.81.8-1.81.42.2-1.21.21.91.02.12.0-2.01.6-0.90.7-1.9-0.6-1.3
Bone: endosteal perimeter0.91.93.11.01.61.51.51.6-1.61.61.3-1.61.51.71.21.20.8-0.91.8-1.41.3-0.8-1.3-0.0
Epididymis fat weight0.00.10.3-0.10.10.20.20.2-0.20.20.0-0.30.30.30.2-0.0-0.20.10.3-0.30.30.1-0.60.3
Delta time in closed arm before/after self-admin0.50.51.4-0.30.20.60.60.6-0.60.3-0.2-1.01.00.50.3-0.4-0.60.60.7-1.11.10.70.11.2
Delta time in open arm before/after self-admin3.02.95.4-1.6-1.8-2.2-2.2-2.12.1-1.7-1.52.3-2.2-1.8-1.6-1.3-1.11.1-1.82.0-2.00.80.5-0.2
Diff in mean of infusions in LGA sessions0.20.20.50.50.60.60.60.6-0.60.60.4-0.50.60.60.10.30.2-0.20.6-0.50.5-0.2-0.7-0.0
Delay discount exponential model param2.22.56.62.01.41.21.21.2-1.20.62.3-0.20.31.20.52.42.6-2.60.80.2-0.3-2.60.6-2.4
Extinction: sum of active levers before priming0.40.40.9-0.6-0.7-0.7-0.7-0.70.7-0.4-0.90.4-0.4-0.6-0.1-0.9-0.90.9-0.50.2-0.10.9-0.10.8
Active lever presses in extinction session 60.10.10.20.20.20.30.30.3-0.30.10.4-0.20.20.40.10.40.4-0.40.3-0.20.1-0.4-0.1-0.1
Bone: final force2.33.66.02.12.12.22.22.2-2.22.41.4-2.42.31.72.41.01.0-0.91.8-2.32.3-0.5-1.80.4
Bone: final moment1.82.94.61.91.92.02.01.9-1.92.21.3-2.12.01.52.21.00.9-0.91.6-2.02.0-0.5-1.50.3
Food consumed during 24 hour testing period0.50.61.90.90.70.50.50.6-0.60.11.10.1-0.00.60.11.21.3-1.30.30.2-0.3-1.30.5-1.4
Glucose1.72.64.3-1.9-1.9-1.8-1.8-1.91.9-1.4-2.11.3-1.3-1.7-1.2-2.0-1.91.9-1.51.0-0.91.80.51.1
Heart weight0.61.02.6-0.31.01.01.01.0-1.01.20.5-1.41.31.40.40.3-0.20.11.6-1.21.20.1-1.30.8
Delay discount hyperbolic model param2.12.36.31.91.41.21.21.2-1.20.52.2-0.20.31.30.42.42.5-2.50.80.2-0.4-2.50.6-2.3
Intermittent access intake day 1-15 change0.91.93.51.81.61.51.51.2-1.21.21.9-0.90.91.50.11.91.8-1.81.2-0.60.4-1.8-0.7-1.3
Intermittent access intake escalation0.81.63.21.71.51.41.41.1-1.11.01.8-0.80.91.3-0.01.81.8-1.81.1-0.50.4-1.7-0.5-1.3
Intermittent access intake escalation 20.30.30.90.70.40.30.30.1-0.1-0.00.70.1-0.10.3-0.80.80.8-0.90.10.4-0.5-0.9-0.1-0.9
Intermitt. access day 1 inactive lever presses0.20.61.60.70.60.60.60.5-0.50.11.20.00.20.7-0.11.21.2-1.20.50.1-0.2-1.30.6-1.1
Intermitt. access day 15 inactive lever presses0.51.13.70.9-0.9-0.8-0.8-0.90.9-1.1-0.21.3-1.2-1.5-0.1-0.10.6-0.4-1.71.1-1.1-0.31.9-1.1
Intermitt. access escalation Index0.10.20.6-0.70.2-0.2-0.20.1-0.10.5-0.4-0.10.10.10.7-0.4-0.70.60.3-0.10.10.5-0.80.7
Intermittent access day 1 total infusions0.40.61.8-1.3-0.3-0.7-0.7-0.50.50.0-1.00.2-0.1-0.1-0.2-1.0-1.41.30.2-0.10.11.1-0.81.3
Intermittent access day 15 total infusions0.20.21.20.10.70.30.30.3-0.30.70.3-0.40.60.8-0.20.3-0.1-0.00.9-0.50.5-0.1-1.10.3
Intermittent access terminal intake (last 3 days)0.10.10.8-0.00.30.00.0-0.00.00.4-0.1-0.10.20.3-0.2-0.1-0.30.20.4-0.20.20.2-0.90.4
Intermittent access total infusions0.30.41.4-0.6-0.2-0.4-0.4-0.40.40.2-0.8-0.00.1-0.2-0.2-0.9-1.11.00.0-0.30.41.0-0.81.2
Intermittent access day 1 locomotion0.70.92.6-1.4-0.6-1.0-1.0-0.70.7-0.1-1.30.4-0.3-0.5-0.1-1.3-1.61.5-0.20.00.11.4-0.51.5
Intermittent access day 15 total locomotion0.50.92.4-0.11.30.80.80.9-0.91.50.6-0.91.11.50.20.5-0.1-0.11.6-0.90.9-0.2-1.50.5
Intermittent access total locomotion0.30.41.6-1.00.1-0.3-0.3-0.20.20.5-0.7-0.10.30.2-0.4-0.7-1.11.00.4-0.30.40.9-0.91.3
Intermittent access standard deviation0.30.72.51.30.20.10.1-0.20.2-0.40.80.6-0.5-0.3-0.30.91.4-1.3-0.60.6-0.7-1.21.2-1.6
Left kidney weight7.534.754.37.47.06.86.87.1-7.16.96.0-6.26.15.46.45.25.3-5.15.3-5.85.6-4.0-3.5-1.6
Right kidney weight5.926.748.16.96.06.06.06.1-6.15.95.2-5.55.54.55.84.44.7-4.54.4-5.25.0-3.4-2.7-1.3
Cocaine induced anxiety0.30.41.4-0.6-0.5-0.4-0.4-0.40.4-0.0-1.0-0.00.0-0.4-0.5-1.1-1.11.1-0.2-0.30.41.2-0.31.0
Post-drug Anxiety5.25.611.6-1.9-2.5-2.6-2.6-2.62.6-1.4-3.41.7-1.7-3.1-0.4-3.4-3.03.1-2.60.9-0.73.20.42.1
Baseline Anxiety3.84.49.2-1.3-2.3-2.5-2.5-2.52.5-1.6-2.62.0-2.0-3.00.4-2.5-1.92.1-2.81.5-1.32.11.01.1
Tail length7.228.246.05.56.26.16.16.1-6.16.84.3-6.46.35.06.53.43.2-3.05.3-6.26.1-2.0-4.70.6
Length with tail13.659.391.18.99.08.88.99.0-9.09.56.8-9.08.97.29.05.55.3-5.17.4-8.78.5-3.6-6.0-0.1
Length without tail8.326.750.37.16.05.85.96.0-6.05.95.4-5.35.24.55.74.75.0-4.84.3-5.04.8-3.7-2.8-1.8
Times rat made contact with spout0.80.91.70.81.11.01.01.2-1.21.30.6-1.21.21.01.10.40.2-0.21.1-1.31.3-0.1-1.20.4
Lifetime Intake0.40.51.2-0.6-0.5-0.9-0.9-0.60.6-0.1-1.00.4-0.4-0.6-0.2-1.1-1.11.1-0.50.1-0.01.1-0.51.0
Liver weight, left4.67.714.63.43.13.13.12.9-2.92.03.8-1.81.82.71.63.73.8-3.82.2-1.20.9-3.6-0.1-2.7
Liver weight, right2.13.77.32.72.32.32.32.3-2.32.12.1-1.81.81.62.01.92.1-2.01.5-1.71.6-1.6-0.5-0.8
Locomotor activity3.24.99.51.12.52.32.32.5-2.52.81.5-2.82.82.91.71.20.4-0.53.1-2.72.6-0.4-3.11.1
Locomotor testing distance1.01.93.71.21.71.31.31.5-1.51.51.6-1.31.21.90.71.61.2-1.31.8-1.11.0-1.3-1.4-0.4
Locomotor testing rearing0.20.41.40.40.20.10.10.1-0.1-0.40.90.3-0.30.5-0.61.01.0-1.00.20.6-0.7-1.20.4-1.1
Locomotion in novel chamber1.52.03.60.71.81.61.51.6-1.61.81.5-1.51.51.91.51.40.9-1.01.9-1.21.2-1.0-1.1-0.1
Locomotion in novel chamber post-restriction1.93.16.60.82.02.12.02.0-2.01.81.4-2.22.32.41.61.20.5-0.62.6-2.02.0-0.6-1.70.8
Fecal boli incidents, locomotor time 11.52.24.21.01.51.91.91.5-1.51.81.1-2.12.01.71.40.80.5-0.51.8-1.81.8-0.3-1.50.6
Change in fecal boli incidents, locomotor task0.40.41.00.3-0.5-0.8-0.8-0.60.6-0.5-0.40.9-0.9-0.90.2-0.30.10.0-1.00.6-0.60.10.6-0.4
Time >=10cm from walls, locomotor time 12.62.84.8-1.5-2.1-1.6-1.6-2.02.0-1.5-2.21.2-1.2-2.0-1.2-2.2-2.02.0-1.80.8-0.72.01.01.4
Bouts of movement, locomotor time 11.41.62.61.31.21.51.51.6-1.61.11.2-1.41.41.51.11.10.8-0.91.5-1.41.3-0.7-0.50.1
Total resting periods, locomotor time 11.21.42.21.21.11.41.41.5-1.51.11.1-1.41.41.40.90.90.7-0.71.5-1.41.4-0.6-0.60.2
Rest time, locomotor task time 11.01.22.91.71.21.31.31.2-1.21.30.9-1.31.41.01.20.70.7-0.71.0-1.31.3-0.4-0.60.1
Distance moved, locomotor task time 10.40.62.3-1.5-0.8-0.7-0.7-0.70.7-0.6-0.90.3-0.4-0.3-0.8-0.8-1.11.0-0.20.3-0.30.8-0.20.8
Vertical activity count, locomotor time 10.10.31.1-1.00.20.60.60.2-0.20.10.1-0.70.70.9-0.40.1-0.40.30.9-0.60.50.1-0.70.6
Time >=10cm from walls, locomotor time 20.30.51.70.5-0.3-0.1-0.1-0.40.40.2-0.9-0.30.4-0.80.5-1.1-0.80.9-0.6-0.80.91.30.21.1
Bouts of movement, locomotor time 20.81.32.31.11.51.41.41.1-1.11.51.1-1.41.41.31.40.90.7-0.71.3-1.21.2-0.6-1.1-0.1
Total resting periods, locomotor time 20.71.22.21.31.51.31.31.0-1.01.41.1-1.21.21.11.41.00.9-0.91.1-1.01.0-0.7-1.0-0.3
Rest time, locomotor task time 20.10.10.2-0.2-0.3-0.4-0.4-0.30.3-0.2-0.40.5-0.4-0.4-0.3-0.3-0.30.3-0.40.4-0.40.20.0-0.1
Distance moved, locomotor task time 20.10.20.60.10.30.40.40.3-0.3-0.10.5-0.30.30.5-0.70.50.4-0.50.5-0.20.2-0.50.2-0.2
Vertical activity count, locomotor time 21.62.24.51.21.52.12.11.6-1.60.91.8-1.71.82.00.41.61.3-1.41.9-1.41.3-1.3-0.1-0.3
Light reinforcement 10.82.15.3-1.6-1.3-1.4-1.4-1.31.3-0.7-2.10.6-0.6-1.2-0.5-2.1-2.32.3-0.80.2-0.12.2-0.71.9
Light reinforcement 20.10.20.6-0.2-0.4-0.6-0.6-0.40.4-0.5-0.20.8-0.6-0.3-0.4-0.0-0.0-0.0-0.40.6-0.6-0.10.6-0.4
Bone: marrow area1.22.64.71.61.81.71.71.8-1.81.32.2-1.21.21.90.92.12.0-2.01.6-0.80.7-2.0-0.5-1.4
Bone: maximum diameter1.01.93.11.81.61.61.61.6-1.61.71.2-1.61.51.21.71.01.0-1.01.2-1.51.5-0.7-1.0-0.1
Bone: maximum force2.03.55.31.92.12.22.22.2-2.22.31.6-2.32.21.92.11.31.1-1.12.0-2.12.1-0.8-1.70.2
Bone: maximum moment1.72.94.31.82.02.12.12.0-2.02.11.5-2.02.01.81.81.31.1-1.11.8-1.91.8-0.9-1.40.0
Mean time between licks in bursts0.71.73.4-1.7-1.4-1.6-1.6-1.41.4-1.6-0.91.6-1.6-1.0-1.9-0.6-0.70.7-1.01.6-1.60.30.9-0.2
Mean num. licks in bursts0.10.20.7-0.4-0.4-0.2-0.2-0.30.3-0.0-0.7-0.10.1-0.40.0-0.7-0.70.8-0.2-0.20.30.8-0.30.8
Cd content in liver0.40.51.4-1.00.20.30.30.2-0.20.3-0.2-0.70.71.0-0.4-0.2-0.90.71.2-0.60.60.5-1.11.1
Co content in liver1.61.85.51.01.01.01.00.9-0.90.12.0-0.10.11.2-0.42.22.2-2.20.80.4-0.6-2.40.8-2.2
Cu content in liver0.10.20.9-0.4-0.3-0.4-0.4-0.50.5-0.50.10.4-0.40.0-0.90.20.1-0.1-0.10.4-0.5-0.20.4-0.3
Fe content in liver0.70.81.90.10.80.90.90.9-0.91.10.3-1.21.21.10.80.1-0.30.21.3-1.21.20.3-1.40.9
K content in liver0.10.10.30.1-0.3-0.3-0.3-0.30.3-0.1-0.40.1-0.2-0.60.2-0.5-0.30.4-0.5-0.00.10.50.10.3
Mg content in liver0.20.21.01.00.50.40.40.4-0.40.60.5-0.40.40.20.60.40.6-0.60.1-0.40.4-0.4-0.1-0.3
Mn content in liver0.30.30.6-0.2-0.5-0.5-0.5-0.50.5-0.6-0.10.7-0.7-0.6-0.5-0.00.2-0.2-0.70.8-0.8-0.20.8-0.6
Na content in liver0.50.51.61.10.80.70.70.7-0.70.90.5-0.70.80.41.30.30.5-0.40.5-0.90.9-0.2-0.50.1
Rb content in liver3.03.45.3-2.3-2.2-2.2-2.2-2.22.2-2.0-1.91.9-1.9-1.7-2.1-1.7-1.71.6-1.71.7-1.61.31.10.6
Se content in liver0.81.02.80.60.00.10.10.1-0.10.9-1.0-0.80.8-0.71.6-1.3-1.01.1-0.3-1.31.41.6-0.91.7
Sr content in liver0.80.71.70.90.70.70.70.7-0.70.31.2-0.20.20.70.21.21.3-1.30.5-0.0-0.1-1.30.2-1.2
Zn content in liver3.94.47.72.62.42.22.22.2-2.21.82.8-1.61.62.21.22.72.7-2.71.9-1.31.1-2.4-0.4-1.7
Bone: minimum diameter0.00.00.0-0.10.00.00.00.0-0.0-0.00.0-0.00.00.1-0.10.1-0.00.00.10.0-0.0-0.0-0.1-0.0
Time in familiar zone, hab. session 10.90.92.50.3-0.5-0.7-0.7-0.60.6-1.00.21.2-1.2-0.8-0.70.40.8-0.8-1.11.3-1.3-0.81.6-1.4
Time in novel zone, hab. session 10.50.51.20.30.50.60.60.6-0.60.9-0.0-1.01.00.50.9-0.2-0.40.40.7-1.11.10.5-1.10.9
Total zone transitions, hab. session 11.01.44.5-2.1-1.2-1.2-1.2-1.21.2-0.9-1.50.7-0.7-0.6-1.3-1.4-1.81.6-0.40.6-0.51.4-0.31.1
Total locomotion distance, hab. session 10.71.02.3-1.4-1.1-1.0-1.0-1.01.0-0.7-1.40.5-0.5-0.9-0.7-1.4-1.51.5-0.60.3-0.21.4-0.21.1
Locomotion velocity, hab. session 11.42.04.3-2.1-1.5-1.5-1.5-1.51.5-1.1-1.90.9-0.9-1.1-1.2-1.8-2.01.9-0.90.6-0.51.7-0.11.3
Time in familiar zone, hab. session 20.20.20.70.3-0.4-0.5-0.5-0.40.4-0.4-0.30.5-0.5-0.80.0-0.30.00.1-0.80.3-0.30.20.7-0.2
Time in novel zone, hab. session 20.20.20.9-1.0-0.2-0.1-0.1-0.20.2-0.2-0.40.00.00.2-0.5-0.3-0.70.60.30.1-0.10.4-0.50.6
Total zone transitions, hab. session 20.20.30.70.10.60.50.50.5-0.50.60.3-0.60.70.80.40.3-0.0-0.00.8-0.60.6-0.1-0.80.3
Total locomotion distance, hab. session 20.10.10.6-0.8-0.3-0.3-0.3-0.30.3-0.1-0.40.1-0.10.0-0.4-0.4-0.60.60.10.0-0.00.5-0.40.4
Locomotion velocity, hab. session 20.10.10.6-0.8-0.2-0.3-0.3-0.20.2-0.1-0.40.1-0.00.1-0.4-0.3-0.60.50.20.0-0.00.4-0.40.4
Novel to familiar place preference ratio0.00.00.2-0.3-0.00.00.0-0.00.00.1-0.2-0.10.20.1-0.1-0.2-0.40.30.2-0.10.20.3-0.40.4
Novelty place preference0.10.10.5-0.7-0.3-0.3-0.3-0.30.3-0.2-0.50.2-0.1-0.1-0.4-0.4-0.60.5-0.00.1-0.10.4-0.20.5
Time in novel zone, NPP test0.10.10.2-0.5-0.2-0.1-0.1-0.20.2-0.1-0.3-0.00.0-0.0-0.2-0.3-0.50.40.1-0.00.10.4-0.30.5
Total zone transitions, NPP test0.10.20.5-0.30.20.20.20.2-0.20.4-0.1-0.50.50.50.1-0.1-0.40.40.6-0.50.50.3-0.70.6
Total locomotion distance, NPP test0.50.72.2-1.0-0.4-0.4-0.4-0.30.30.2-1.1-0.30.3-0.20.0-1.2-1.41.40.1-0.50.61.4-1.01.5
Locomotion velocity, NPP test0.40.62.2-1.0-0.1-0.0-0.0-0.00.00.4-0.8-0.60.60.30.1-0.9-1.31.20.6-0.70.81.2-1.31.5
Intraocular pressure1.62.33.61.51.81.81.81.9-1.91.31.8-1.51.61.90.91.61.4-1.41.8-1.41.3-1.3-0.5-0.5
Delta distance traveled before/after self-admin0.60.61.40.41.10.60.60.5-0.50.71.1-0.30.41.1-0.21.21.0-1.00.9-0.10.0-1.1-0.7-0.8
Delta ambulatory time before/after self-admin0.20.20.8-0.30.3-0.3-0.3-0.30.30.00.40.5-0.50.3-0.90.60.4-0.50.10.6-0.7-0.7-0.3-0.8
Parametrial fat weight0.10.31.70.6-0.4-0.3-0.3-0.20.2-0.1-0.50.4-0.4-1.30.4-0.50.10.1-1.30.2-0.10.40.8-0.1
Pavlov. Cond. lever latency2.32.85.32.32.01.81.81.9-1.91.72.0-1.51.41.51.81.81.9-1.81.4-1.31.2-1.6-0.7-0.9
Pavlov. Cond. magazine entry latency0.40.51.10.20.60.70.70.6-0.60.90.1-1.01.00.70.7-0.1-0.30.20.8-1.01.00.3-1.00.8
Pavlov. Cond. change in total contacts1.31.33.4-1.1-1.2-1.0-1.0-1.11.1-0.5-1.70.3-0.3-1.3-0.2-1.8-1.71.8-1.00.00.11.8-0.11.6
Pavlov. Cond. index score0.30.41.0-0.7-0.5-0.4-0.4-0.50.5-0.2-0.90.0-0.0-0.5-0.2-0.9-1.01.0-0.3-0.10.11.0-0.30.9
Pavlov. Cond. latency score0.60.71.8-1.1-0.9-0.7-0.7-0.80.8-0.4-1.20.3-0.2-0.7-0.5-1.3-1.41.3-0.50.1-0.01.3-0.21.1
Pavlov. Cond. lever contacts2.12.54.0-2.0-1.9-1.7-1.7-1.81.8-1.6-1.91.3-1.3-1.6-1.5-1.8-1.81.8-1.41.1-1.01.60.61.0
Pavlov. Cond. magazine entry number0.40.51.4-0.0-0.6-0.6-0.6-0.60.6-0.90.01.0-1.1-0.7-0.60.20.5-0.4-0.91.1-1.1-0.51.2-1.0
Pavlov. Cond. intertrial magazine entries0.70.81.9-1.2-1.0-1.0-1.0-0.90.9-1.2-0.51.1-1.2-0.6-1.4-0.3-0.40.3-0.71.2-1.20.00.8-0.4
Pavlov. Cond. lever-magazine prob. diff.0.30.30.9-0.6-0.5-0.4-0.4-0.50.5-0.2-0.90.1-0.0-0.6-0.2-0.9-0.90.9-0.4-0.00.10.9-0.10.8
Pavlov. Cond. response bias0.20.30.8-0.30.10.20.20.2-0.20.4-0.3-0.60.70.30.2-0.4-0.60.60.5-0.70.70.6-0.80.9
Pavlov. Cond. lever latency0.50.72.21.10.40.40.40.3-0.3-0.21.00.3-0.30.1-0.21.11.4-1.4-0.20.5-0.6-1.31.0-1.5
Pavlov. Cond. magazine entry latency2.32.86.3-2.1-1.7-1.7-1.7-1.61.6-0.9-2.40.8-0.7-1.5-0.7-2.4-2.52.5-1.10.3-0.22.4-0.42.1
Pavlov. Cond. change in total contacts0.30.51.7-1.2-0.2-0.3-0.3-0.20.20.1-0.8-0.30.30.3-0.1-0.8-1.31.20.5-0.40.41.0-1.01.3
Pavlov. Cond. index score1.11.54.3-1.9-1.0-1.0-1.0-1.01.0-0.4-1.60.2-0.2-0.5-0.4-1.7-2.12.0-0.2-0.00.11.8-0.91.8
Pavlov. Cond. latency score1.11.54.2-1.8-1.1-1.1-1.1-1.01.0-0.4-1.70.3-0.3-0.7-0.4-1.7-2.12.0-0.3-0.00.11.9-0.81.8
Pavlov. Cond. lever contacts0.70.92.9-1.3-0.5-0.6-0.6-0.50.50.1-1.3-0.20.2-0.20.1-1.4-1.71.60.1-0.50.61.6-1.11.7
Pavlov. Cond. magazine entry number1.72.14.92.11.51.51.51.4-1.40.91.9-0.70.71.00.91.92.2-2.10.7-0.40.3-2.00.4-1.7
Pavlov. Cond. intertrial magazine entries0.91.32.01.01.41.41.41.3-1.31.21.2-1.21.21.40.91.10.9-1.01.3-0.90.9-0.9-0.8-0.3
Pavlov. Cond. lever-magazine prob. diff.1.21.64.9-2.0-1.1-1.1-1.1-1.01.0-0.4-1.70.2-0.2-0.5-0.5-1.8-2.22.1-0.2-0.10.21.9-0.91.9
Pavlov. Cond. response bias1.31.75.3-2.0-0.9-1.0-1.0-0.90.9-0.2-1.70.00.0-0.4-0.3-1.8-2.32.2-0.0-0.30.42.1-1.22.2
Time in closed arm before self-admin2.12.74.71.42.11.71.71.8-1.81.71.9-1.51.72.20.51.81.5-1.52.0-1.41.3-1.5-1.4-0.6
Time in closed arm after self-admin2.62.86.20.71.92.02.02.0-2.01.61.6-2.02.32.40.31.40.8-0.92.5-2.01.9-0.8-0.90.4
Time in open arm before self-admin0.30.41.6-0.6-0.10.40.40.1-0.10.3-0.5-0.80.60.10.5-0.6-0.80.80.3-0.60.70.8-0.41.3
Time in open arm after self-admin1.51.62.7-1.0-1.5-1.5-1.5-1.51.5-1.1-1.41.4-1.6-1.7-0.5-1.3-1.11.1-1.61.3-1.31.00.20.1
Bone: periosteal estimation1.53.24.71.92.12.12.12.1-2.12.21.6-2.12.01.82.01.31.2-1.21.9-2.01.9-0.9-1.5-0.0
Bone: periosteal perimeter0.81.32.80.51.11.11.11.1-1.11.50.3-1.61.51.11.30.0-0.30.21.4-1.61.60.4-1.71.1
Bone: post-yield work0.20.40.70.40.70.70.70.7-0.70.60.7-0.60.60.80.40.60.5-0.50.8-0.50.5-0.5-0.5-0.2
Progressive ratio test 1 active lever presses1.11.43.21.41.51.01.01.3-1.31.80.8-1.21.31.11.60.60.4-0.41.2-1.41.4-0.2-1.60.5
Progressive ratio test 1 breakpoint1.11.33.11.41.41.01.01.3-1.31.70.8-1.21.31.11.50.50.4-0.41.2-1.41.4-0.2-1.50.5
Progressive ratio test 1 inactive lever presses1.21.73.01.21.71.21.21.5-1.51.41.7-0.81.01.70.51.71.5-1.51.5-0.70.6-1.5-0.6-1.0
Progressive ratio test 2 active lever presses1.21.42.80.91.41.31.31.4-1.41.41.1-1.41.51.60.61.00.6-0.71.7-1.31.3-0.6-1.30.3
Progressive ratio test 2 breakpoint1.21.32.70.81.31.31.31.3-1.31.31.1-1.41.41.60.50.90.5-0.61.6-1.31.2-0.5-1.30.4
Progressive ratio test 2 inactive lever presses2.74.37.32.22.42.42.42.3-2.31.72.7-1.81.92.70.62.62.2-2.32.5-1.51.4-2.2-0.5-1.1
Incentive Sensitization - Responses0.00.00.6-0.3-0.10.10.1-0.00.0-0.20.2-0.00.00.3-0.80.20.1-0.10.20.1-0.1-0.2-0.1-0.0
Incentive Sensitization - Breakpoint0.00.10.7-0.4-0.10.00.0-0.10.1-0.30.10.0-0.00.2-0.80.20.0-0.10.20.2-0.2-0.2-0.1-0.0
Sum of active levers in priming session hrs 5-60.20.20.80.6-0.5-0.3-0.3-0.40.4-0.3-0.50.3-0.3-0.90.5-0.6-0.20.3-0.80.00.00.50.70.1
Progressive ratio0.50.71.8-0.7-0.9-0.8-0.9-1.11.1-0.9-0.80.9-0.9-1.1-0.2-0.7-0.50.5-1.11.0-0.90.41.3-0.0
Food seeking constrained by brief footshock1.92.36.2-0.2-0.7-1.1-1.1-1.11.1-1.60.32.1-1.9-0.9-2.20.71.0-1.0-1.32.2-2.3-1.32.0-2.5
Seeking ratio, punishment vs. effort0.60.81.51.01.10.80.91.0-1.00.71.2-0.50.61.0-0.11.21.1-1.20.9-0.40.4-1.1-0.6-1.0
Retroperitoneal fat weight0.31.44.3-0.1-1.3-1.2-1.3-0.90.9-0.5-1.70.7-0.8-2.10.8-1.8-1.21.4-1.80.3-0.11.70.31.0
Reaction time number correct0.91.73.60.81.51.31.31.2-1.21.11.8-0.70.71.80.21.91.6-1.71.5-0.40.2-1.8-0.8-1.3
Reaction time mean minus median1.12.810.4-1.10.0-0.0-0.00.1-0.11.3-1.7-1.31.3-0.01.2-2.1-2.52.50.6-1.81.92.7-2.63.2
Reaction time mean minus median AUC0.51.34.6-1.5-0.2-0.5-0.5-0.20.20.5-1.3-0.50.40.00.1-1.5-2.01.90.4-0.70.81.7-1.82.1
Reaction time num false alarms0.50.72.5-1.4-0.2-0.2-0.2-0.30.30.3-0.9-0.50.50.30.1-1.0-1.51.40.6-0.60.61.3-1.31.6
Reaction time num false alarms AUC0.30.41.5-1.10.00.00.0-0.10.10.4-0.5-0.50.50.40.2-0.6-1.11.00.6-0.60.60.9-1.01.2
Reaction time trials correct on left0.91.73.60.81.51.31.31.2-1.21.11.8-0.70.71.80.21.91.6-1.71.5-0.40.2-1.8-0.8-1.3
Reaction time trials on left0.81.63.30.71.41.31.31.2-1.21.11.8-0.70.71.70.21.81.5-1.61.5-0.40.2-1.7-0.8-1.2
Reaction time mean2.94.69.8-2.3-2.1-2.3-2.3-2.02.0-1.1-3.11.2-1.3-2.2-0.8-3.1-3.13.1-1.80.7-0.53.0-0.52.4
Reaction time mean AUC2.84.59.3-2.3-2.2-2.3-2.3-2.12.1-1.2-3.01.2-1.3-2.1-0.9-3.0-3.03.1-1.70.8-0.62.9-0.52.3
Median of all reaction times3.95.69.7-2.4-2.7-2.7-2.7-2.62.6-1.9-3.12.0-2.0-2.8-1.4-3.0-2.82.8-2.51.5-1.32.70.51.7
Reaction time omissions0.81.23.1-1.3-0.9-1.0-1.0-0.60.6-0.4-1.60.3-0.3-0.9-0.5-1.6-1.81.7-0.5-0.10.21.7-0.41.7
Reaction time false alarm rate0.71.03.5-1.3-0.6-0.5-0.5-0.60.6-0.1-1.4-0.20.3-0.40.2-1.5-1.81.70.0-0.50.61.7-0.71.9
Reaction time premature initiation rate0.40.61.9-0.60.10.30.30.3-0.30.7-0.7-0.70.60.00.8-0.9-1.01.00.3-0.70.81.1-1.11.4
Reaction time premature initiations0.30.52.0-0.20.70.70.70.7-0.71.10.1-0.90.80.70.80.0-0.30.20.8-0.70.80.2-1.40.6
Std. dev. reaction times1.32.57.8-1.5-0.8-1.1-1.1-0.60.60.3-2.2-0.20.1-0.90.3-2.5-2.72.7-0.4-0.70.92.7-1.62.8
Reaction time trials completed0.81.63.30.71.41.31.31.2-1.21.11.8-0.70.71.70.21.81.5-1.61.5-0.40.2-1.7-0.8-1.2
Reaction time trials AUC0.71.32.90.51.31.11.11.0-1.00.91.6-0.60.61.60.01.71.4-1.51.4-0.20.1-1.6-0.8-1.2
Run reversals in cocaine runway, females0.90.91.8-0.9-1.0-1.0-1.0-1.11.1-1.2-0.71.3-1.2-1.0-1.1-0.5-0.30.3-1.11.2-1.20.21.0-0.4
Run reversals in cocaine runway, males0.40.41.6-0.60.40.40.40.5-0.5-0.10.7-0.00.21.1-1.20.80.4-0.51.00.1-0.2-0.8-0.0-1.0
Latency to leave start box in cocaine runway0.20.20.60.0-0.2-0.5-0.5-0.40.40.4-0.60.2-0.4-0.70.8-0.6-0.40.5-0.60.1-0.10.5-0.70.3
Latency to leave start box in cocaine runway, F0.10.10.50.70.1-0.2-0.2-0.00.00.30.00.0-0.3-0.50.7-0.00.4-0.3-0.6-0.10.1-0.00.1-0.3
Latency to leave start box in cocaine runway, M0.30.21.6-0.7-0.0-0.3-0.3-0.30.30.5-0.50.1-0.2-0.10.5-0.5-0.70.6-0.00.2-0.10.5-1.30.6
Std. dev. time between licks in bursts0.30.41.2-0.20.60.60.60.6-0.60.70.3-0.80.81.00.30.3-0.10.01.1-0.70.7-0.0-1.10.5
Total sessions with >9 infusions0.30.30.90.2-0.4-0.9-0.9-0.50.5-0.3-0.50.9-0.8-0.90.3-0.5-0.20.2-0.90.6-0.50.30.4-0.1
Short access day 1 total inactive lever presses0.40.51.91.10.40.20.20.3-0.30.20.80.3-0.3-0.00.30.91.2-1.2-0.30.4-0.4-1.10.7-1.4
Short access day 10 total inactive lever presses1.12.78.42.61.21.21.21.1-1.10.42.2-0.20.20.60.62.32.9-2.70.10.0-0.2-2.51.5-2.5
Short access day 1 total infusions1.01.32.7-0.4-1.2-1.5-1.5-1.01.0-1.2-0.91.7-1.6-1.5-0.7-0.7-0.30.4-1.61.4-1.40.31.1-0.5
Short access day 10 total infusions0.40.51.0-0.5-0.8-1.0-1.0-0.70.7-0.7-0.70.9-0.9-0.8-0.5-0.6-0.50.5-0.80.7-0.70.40.30.1
Short access total infusions1.11.43.1-0.4-1.2-1.7-1.7-1.21.2-0.8-1.31.5-1.5-1.8-0.1-1.3-0.91.0-1.71.0-0.91.00.40.2
Short access day 1 locomotion0.70.82.5-0.9-0.4-0.6-0.6-0.40.40.4-1.3-0.00.0-0.50.5-1.4-1.61.5-0.2-0.30.41.5-0.91.6
Short access day 10 total locomotion0.10.30.90.40.50.10.10.2-0.20.10.70.4-0.20.20.30.80.9-0.90.00.4-0.4-0.90.5-1.0
Short access total locomotion0.70.81.5-0.7-0.7-1.2-1.2-1.01.0-0.3-1.20.9-0.8-1.10.0-1.2-1.11.1-1.00.5-0.41.10.10.8
One hour access (0.3 mA shock)2.12.56.80.81.81.71.71.6-1.61.32.0-1.31.52.6-0.42.01.2-1.42.5-1.00.9-1.6-1.5-0.5
Compulsive drug intake1.31.63.3-1.5-1.5-1.3-1.3-1.31.3-1.8-0.91.5-1.5-1.0-1.6-0.6-0.70.6-1.11.6-1.60.31.2-0.2
One hour access (shock baseline)1.82.85.61.12.01.81.81.8-1.82.11.3-2.02.22.20.81.00.4-0.52.4-2.12.0-0.4-2.00.7
Social response proportion4.85.410.81.72.32.62.62.4-2.43.10.9-3.23.11.93.10.30.1-0.02.3-3.33.30.5-2.71.7
Social responses2.53.25.41.02.12.02.02.0-2.02.31.2-2.32.32.11.70.90.4-0.52.3-2.22.1-0.3-2.20.8
Social time1.72.34.8-2.2-1.7-1.6-1.6-1.61.6-1.2-2.01.0-1.0-1.1-1.3-1.9-2.22.1-0.80.8-0.71.8-0.31.5
Soleus weight1.44.26.22.22.42.52.52.4-2.42.32.2-2.22.12.32.01.91.7-1.72.2-1.91.8-1.5-1.5-0.5
Bone: stiffness0.91.43.00.41.11.21.21.1-1.11.50.3-1.61.61.21.20.1-0.30.31.4-1.61.60.4-1.71.2
Tibialis anterior weight5.719.231.24.94.95.25.25.0-5.05.53.3-5.45.33.95.62.52.3-2.24.2-5.35.2-1.3-3.90.8
Time to tail flick, vehicle, before self-admin1.61.74.4-0.8-1.4-1.0-1.0-1.21.2-0.6-2.00.6-0.5-1.60.1-2.1-1.92.0-1.30.10.02.1-0.01.6
Time to tail flick, vehicle, after self-admin0.10.20.5-0.6-0.1-0.1-0.10.1-0.10.0-0.3-0.50.30.3-0.3-0.4-0.60.50.4-0.50.50.5-0.50.7
Time to tail flick, test, before self-admin1.31.42.21.31.51.31.31.4-1.41.41.3-1.31.21.30.81.11.1-1.11.2-1.11.1-0.9-0.9-0.4
Time to tail flick, test, after self-admin0.40.40.9-0.2-0.4-0.6-0.6-0.60.60.2-0.90.2-0.3-0.90.7-1.0-0.70.8-0.80.1-0.10.9-0.60.4
Delta time to tail flick, vehicle, before/after SA0.20.20.9-0.60.20.00.00.2-0.2-0.10.4-0.1-0.00.7-1.00.50.2-0.30.60.1-0.1-0.5-0.1-0.3
Delta time to tail flick, test, before/after SA1.11.11.8-0.8-1.3-1.1-1.1-1.31.3-1.2-1.01.2-1.2-1.3-0.6-0.9-0.70.7-1.31.2-1.10.60.8-0.0
Tibia length3.08.218.34.33.23.43.43.3-3.33.32.7-3.13.12.13.72.22.6-2.42.1-3.03.0-1.6-1.4-0.6
Ambulatory time before self-admin0.30.41.5-0.9-0.7-0.1-0.1-0.10.1-0.4-0.8-0.20.1-0.2-0.4-0.9-1.11.0-0.0-0.20.31.0-0.11.2
Ambulatory time after self-admin0.20.31.9-1.2-0.5-0.2-0.2-0.30.3-0.5-0.40.1-0.20.1-1.4-0.4-0.70.60.10.2-0.20.4-0.30.7
Bone: tissue strength0.80.83.20.70.20.10.10.1-0.1-0.51.00.6-0.60.1-0.61.21.5-1.4-0.30.9-1.0-1.51.2-1.8
Total heroin consumption3.03.66.6-2.5-2.1-1.8-1.8-2.12.1-1.9-2.41.3-1.2-1.5-2.0-2.3-2.62.5-1.21.0-0.82.20.61.9
Bone: trabecular number2.64.37.32.72.42.42.42.4-2.42.12.4-2.02.02.02.22.12.2-2.21.8-1.71.6-1.8-0.9-1.0
Bone: trabecular spacing2.63.44.9-2.1-2.2-2.2-2.2-2.12.1-2.2-1.72.1-2.2-1.9-2.1-1.4-1.31.2-1.92.0-2.00.91.50.0
Bone: trabecular thickness3.13.96.12.52.22.42.42.2-2.22.22.0-2.12.11.82.31.71.7-1.71.8-1.91.8-1.3-1.1-0.5
Bone: trabecular tissue density2.02.910.9-0.9-0.4-0.2-0.2-0.30.30.9-2.0-1.21.1-0.51.1-2.4-2.72.70.2-1.71.92.9-2.03.3
Water consumed over 24 hours2.63.55.12.22.32.12.12.2-2.21.82.2-1.61.62.01.72.12.0-2.01.9-1.41.3-1.8-0.9-1.1
Number of responses in last shaping day0.30.30.8-0.4-0.5-0.9-0.9-0.50.5-0.4-0.60.8-0.7-0.7-0.6-0.6-0.40.5-0.70.5-0.50.40.50.2