Hub : Traits : Tibialis anterior weight : ← : →

chr2:227,864,954-231,132,460

Trait: Tibialis anterior weight

Best TWAS P = 8.22e-11 · Best GWAS P= 1.89e-11 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Dnajb14	gene expression	Dnajb14	0.23	222	0.23	4.5e-25	-6.29	3.13e-10	0.17	FALSE
Adipose	Rap1gds1	gene expression	Rap1gds1	0.25	40	0.21	2.4e-23	5.31	1.10e-07	0.2	FALSE
Adipose	Stpg2	gene expression	Stpg2	0.13	1	0.13	2.3e-14	6.28	3.38e-10	0.59	FALSE
Adipose	Trmt10a	gene expression	Trmt10a	0.17	3818	0.12	3.8e-13	5.42	6.05e-08	0.05	FALSE
Adipose	Rap1gds1	mRNA stability	Rap1gds1	0.12	160	0.1	3.7e-11	6.1	1.07e-09	0.43	FALSE
BLA	Rap1gds1	alternative TSS	XM_039102477.2	0.12	64	0.04	2.2e-03	5.41	6.29e-08	0.17	FALSE
BLA	Tspan5	gene expression	Tspan5	0.63	19	0.27	8.1e-15	5.82	5.82e-09	0.8	FALSE
Brain	Rap1gds1	gene expression	Rap1gds1	0.42	80	0.5	6.6e-53	5.62	1.95e-08	0.71	FALSE
Brain	Stpg2	gene expression	Stpg2	0.05	1	0.06	6.2e-06	5.83	5.71e-09	0.05	FALSE
Brain	Tspan5	gene expression	Tspan5	0.67	48	0.5	9.3e-53	5.59	2.26e-08	0.67	FALSE
Brain	LOC120100955	mRNA stability	LOC120100955	0.03	1	0.04	4.7e-05	-5.35	8.56e-08	0.04	FALSE
Brain	Rap1gds1	mRNA stability	Rap1gds1	0.28	32	0.32	3.6e-30	5.49	4.02e-08	0.49	FALSE
Brain	Trmt10a	mRNA stability	Trmt10a	0.1	34	0.08	6.8e-08	-5.79	7.19e-09	0.25	FALSE
Eye	Trmt10a	alternative TSS	NM_001044232.1	0.46	3818	0.17	1.6e-03	-5.44	5.41e-08	0.13	FALSE
Eye	LOC102547266	gene expression	LOC102547266	0.6	27	0.13	4.5e-03	5.49	4.09e-08	0.31	FALSE
IC	Rap1gds1	gene expression	Rap1gds1	0.45	55	0.22	1.2e-09	6.02	1.80e-09	0.67	FALSE
IC	Tspan5	gene expression	Tspan5	0.56	7	0.38	5.9e-17	5.83	5.63e-09	0.77	FALSE
IL	Tspan5	gene expression	Tspan5	0.55	203	0.25	8.9e-07	5.21	1.85e-07	0.58	FALSE
IL	Emcn	mRNA stability	Emcn	0.2	1	0.09	3.3e-03	5.24	1.59e-07	0.05	FALSE
LHb	Tspan5	gene expression	Tspan5	0.41	55	0.24	2.3e-06	5.42	6.12e-08	0.55	FALSE
Liver	Adh7	gene expression	Adh7	0.55	71	0.4	1.1e-47	-5.52	3.45e-08	0.37	FALSE
Liver	Mttp	gene expression	Mttp	0.3	21	0.25	5.6e-28	5.59	2.24e-08	0.18	FALSE
Liver	Rap1gds1	gene expression	Rap1gds1	0.25	1	0.24	9.8e-27	5.8	6.71e-09	0.22	FALSE
Liver	Trmt10a	gene expression	Trmt10a	0.08	3818	0.04	1.1e-05	5.82	5.97e-09	0.4	FALSE
Liver	Tspan5	gene expression	Tspan5	0.05	1	0.03	5.0e-04	5.91	3.51e-09	0.13	FALSE
Liver	LOC120100951	isoform ratio	XR_005501330.2	0.18	4040	0.11	4.0e-12	-6.22	4.96e-10	0.43	FALSE
NAcc	Eif4e	isoform ratio	XM_063281174.1	0.04	1	0.03	8.8e-05	-5.64	1.71e-08	0.4	FALSE
OFC	Ddit4l	gene expression	Ddit4l	0.38	20	0.17	6.6e-05	5.49	4.01e-08	0.56	FALSE
OFC	Rap1gds1	gene expression	Rap1gds1	0.23	1	0.14	3.4e-04	6.07	1.26e-09	0.06	FALSE
OFC	Tspan5	gene expression	Tspan5	0.45	1	0.27	3.6e-07	5.82	6.03e-09	0.31	FALSE
OFC	Tspan5	isoform ratio	NM_001004090.2	0.23	1	0.09	3.4e-03	-5.81	6.15e-09	0.06	FALSE
OFC	Tspan5	isoform ratio	XM_039102726.2	0.24	1	0.09	3.3e-03	5.81	6.15e-09	0.06	FALSE
OFC	Rap1gds1	mRNA stability	Rap1gds1	0.19	59	0.12	7.7e-04	5.36	8.19e-08	0.29	FALSE
PL	Tspan5	alternative TSS	NM_001004090.2	0.05	3306	0.02	2.3e-03	5.43	5.78e-08	0.64	FALSE
PL	Rap1gds1	gene expression	Rap1gds1	0.17	2556	0.23	1.0e-24	6.35	2.18e-10	0.66	FALSE
PL	Tspan5	gene expression	Tspan5	0.56	41	0.33	6.7e-37	5.52	3.34e-08	0.66	FALSE
PL	Tspan5	isoform ratio	NM_001004090.2	0.24	43	0.17	4.7e-18	-5.26	1.43e-07	0.58	FALSE
PL	Tspan5	isoform ratio	XM_039102726.2	0.24	44	0.17	5.9e-18	5.26	1.43e-07	0.55	FALSE
PL	Rap1gds1	mRNA stability	Rap1gds1	0.06	2556	0.06	1.6e-07	5.88	4.11e-09	0.68	FALSE
pVTA	LOC102555623	alternative TSS	XR_352069.4	0.08	3922	0.05	7.5e-05	5.21	1.87e-07	0.26	FALSE
pVTA	Rap1gds1	gene expression	Rap1gds1	0.15	1	0.17	1.5e-13	6.5	8.22e-11	0.95	TRUE
pVTA	LOC102547266	intron excision ratio	chr2_229921819_229932481	0.07	3253	0.04	2.4e-04	-5.24	1.58e-07	0.66	FALSE
pVTA	LOC102547266	intron excision ratio	chr2_229931002_229932481	0.1	1	0.09	1.1e-07	5.79	7.10e-09	0.58	FALSE
pVTA	Rap1gds1	mRNA stability	Rap1gds1	0.06	1	0.06	1.6e-05	6.01	1.88e-09	0.14	FALSE
RMTg	Rap1gds1	gene expression	Rap1gds1	0.12	1	0.12	4.5e-04	6.05	1.42e-09	0.06	FALSE
RMTg	Stpg2	isoform ratio	XM_017591047.3	0.16	2564	0.11	6.4e-04	-5.86	4.66e-09	0.23	FALSE