Best TWAS P=3.264237e-07 · Best GWAS P=3.589899e-07 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Ndufc1 | isoform ratio | ENSRNOT00000108803 | 0.18 | 0.15 | enet | 140 | 0.16 | 7.4e-18 | -5 | -5.1 | 3.3e-07 | 0.97 | 0.32 | 0.68 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.