Hub : Genes

mrpl11

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability mrpl11 0.07 0.05 8.6e-05 0.04 0.04 0.03 0.04 5.2e-04 2.0e-04 1.4e-03 7.4e-04
2 OFC gene expression mrpl11 0.16 0.12 7.3e-03 0.03 0 0.03 0.01 7.5e-02 2.6e-01 7.6e-02 1.8e-01
3 PL mRNA stability mrpl11 0.11 0.07 5.6e-12 0.1 0.11 0.1 0.1 5.8e-11 1.1e-11 2.6e-11 3.1e-11
4 NAcc mRNA stability mrpl11 0.2 0.17 2.1e-12 0.07 0.08 0.07 0.07 9.8e-11 9.3e-12 2.3e-11 3.5e-11
5 BLA mRNA stability mrpl11 0.09 0.06 5.1e-04 0.05 0.04 0.02 0.03 8.3e-04 4.6e-03 3.5e-02 8.6e-03
6 IC gene expression mrpl11 0.33 0.15 3.7e-11 0.25 0.25 0.25 0.25 5.3e-11 6.0e-11 7.0e-11 6.2e-11
7 RMTg mRNA stability mrpl11 0.11 0.08 9.7e-03 0.04 0.01 -0.01 0 3.8e-02 1.6e-01 7.8e-01 2.4e-01
8 Adipose gene expression mrpl11 0.17 0.07 1.0e-14 0.1 0.11 0.1 0.11 2.0e-11 4.7e-12 9.1e-11 6.9e-12
9 Adipose mRNA stability mrpl11 0.1 0.06 2.4e-06 0.05 0.03 0.04 0.04 5.3e-06 2.2e-04 3.5e-05 1.6e-05
10 IL gene expression mrpl11 0.32 0.17 1.2e-04 0.1 0.04 0.09 0.01 1.8e-03 5.1e-02 4.2e-03 1.7e-01
11 Brain mRNA stability mrpl11 0.22 0.14 7.9e-14 0.16 0.16 0.15 0.16 2.7e-14 2.2e-14 9.0e-14 1.3e-14
12 Liver mRNA stability mrpl11 0.04 0.03 6.0e-04 0.01 0 0 0 2.2e-02 1.1e-01 2.7e-01 2.1e-01
13 PL gene expression mrpl11 0.27 0.1 0.0e+00 0.3 0.32 0.31 0.31 3.0e-33 1.1e-35 2.9e-34 9.6e-35
14 IL mRNA stability mrpl11 0.23 0.13 2.7e-04 0.05 0.04 0.05 -0 2.6e-02 3.2e-02 2.2e-02 4.5e-01
15 Liver gene expression mrpl11 0.28 0.11 0.0e+00 0.16 0.15 0.15 0.16 2.8e-17 1.5e-16 1.1e-16 6.8e-17
16 BLA gene expression mrpl11 0.34 0.13 1.9e-15 0.24 0.25 0.25 0.26 3.6e-13 1.9e-13 2.6e-13 8.6e-14
17 NAcc gene expression mrpl11 0.41 0.16 0.0e+00 0.29 0.31 0.3 0.31 6.5e-44 2.1e-47 1.4e-45 7.7e-48
18 Brain gene expression mrpl11 0.2 0.09 0.0e+00 0.21 0.22 0.2 0.2 4.5e-19 4.2e-20 1.0e-18 7.0e-19

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density1.32.36.80.40.8-0.6-1.2-1.3-1.3-1.42.6-1.1-1.1-1.5-1.2-1.5-1.62.3-2.1-1.7-1.8
Area under the delay curve0.70.81.5-0.6-0.6-0.7-0.7-1.2-0.8-0.90.7-0.6-0.6-0.7-1.1-1.0-0.90.6-1.2-1.0-1.1
BMI with tail1.13.918.11.62.30.1-0.9-1.2-1.3-1.34.3-0.7-0.7-1.3-1.2-1.5-1.73.8-2.4-1.9-2.3
BMI without tail0.41.15.51.11.50.50.2-0.2-0.3-0.32.30.00.0-0.4-0.9-0.7-1.12.1-1.1-0.7-1.4
Body weight0.83.511.53.33.42.51.81.51.51.52.61.91.91.31.21.10.82.20.30.70.3
Weight adjusted by age1.21.73.81.72.01.61.41.41.41.40.41.31.31.21.61.31.30.10.91.21.1
Bone surface1.32.412.52.52.81.0-0.1-0.3-0.2-0.23.50.20.2-0.40.5-0.1-0.33.3-1.5-1.0-0.6
Bone volume1.01.88.41.31.60.0-0.9-0.9-0.9-0.92.9-0.5-0.5-1.0-0.3-0.8-0.82.5-1.8-1.4-1.1
Breakpoint value in progressive ratio session1.21.54.82.21.91.61.00.91.11.11.41.01.00.81.61.10.81.30.10.60.7
Number of licking bursts0.10.20.50.70.60.40.10.00.40.40.60.30.30.30.60.30.50.6-0.2-0.10.2
Context. condit. distance diff. score0.91.02.9-1.7-1.2-1.4-0.9-0.7-1.1-0.8-0.8-1.2-1.2-0.8-1.2-1.0-1.1-0.6-0.5-0.5-0.8
Locomotion velocity, session 10.50.51.20.0-0.10.40.80.60.70.8-0.90.90.90.80.10.61.1-1.10.70.70.6
Locomotion distance, session 10.40.52.00.30.3-0.1-0.3-0.7-0.5-0.51.4-0.1-0.1-0.4-0.7-0.7-0.71.0-1.0-0.8-1.0
Locomotion velocity, session 20.91.13.61.71.91.41.10.90.80.91.01.31.30.90.70.80.80.60.40.60.4
Locomotion distance, session 20.20.21.10.70.50.40.3-0.20.1-0.01.10.60.60.1-0.4-0.2-0.20.5-0.3-0.2-0.5
Locomotion velocity, session 30.40.40.7-0.5-0.3-0.7-0.7-0.8-0.7-0.70.5-0.5-0.5-0.7-0.7-0.8-0.60.4-0.8-0.7-0.9
Locomotion distance, session 30.00.00.2-0.1-0.1-0.10.0-0.1-0.1-0.0-0.00.10.10.0-0.1-0.10.4-0.1-0.10.1-0.1
Stereotopy head waving bouts, day 30.91.12.3-1.3-1.3-1.1-0.9-0.9-1.1-1.10.1-0.9-0.9-1.1-1.5-1.2-1.20.0-0.8-0.9-1.3
Stereotopy head waving duration, day 31.41.62.3-1.4-1.4-1.4-1.3-1.2-1.3-1.40.2-1.3-1.3-1.4-1.5-1.4-1.50.2-1.0-1.2-1.4
Locomotion velocity, session 70.80.91.6-0.7-0.1-0.8-0.7-0.7-1.1-0.80.7-1.0-1.0-0.9-1.1-1.1-1.20.7-0.9-1.0-1.3
Locomotion distance, session 70.10.10.3-0.20.30.00.30.3-0.2-0.10.20.00.0-0.0-0.5-0.3-0.50.0-0.00.0-0.6
Stereotopy head waving bouts, day 71.01.11.8-0.30.1-0.9-1.2-1.0-1.3-1.21.2-1.2-1.2-1.3-0.7-1.0-0.71.2-1.3-1.1-1.0
Stereotopy head waving duration, day 70.70.93.50.71.1-0.1-0.7-0.5-0.9-0.71.9-0.7-0.7-0.9-0.3-0.6-0.41.9-1.1-0.9-0.8
Locomotion velocity, session 80.91.01.71.11.01.21.20.91.11.2-0.11.31.31.10.71.01.1-0.30.90.90.8
Locomotion distance, session 80.30.40.8-0.8-0.6-0.8-0.6-0.7-0.8-0.70.1-0.6-0.6-0.5-0.8-0.8-0.9-0.2-0.6-0.5-0.8
Degree of sensitization distance0.20.20.8-0.10.3-0.2-0.1-0.2-0.4-0.30.5-0.3-0.3-0.4-0.6-0.5-0.90.5-0.4-0.5-0.7
Degree of sensitization stereotypy0.40.41.80.71.10.0-0.5-0.2-0.6-0.41.3-0.4-0.4-0.60.2-0.30.01.2-0.7-0.4-0.3
Conditioned locomotion1.92.13.41.51.61.71.81.61.71.8-0.21.61.61.61.21.51.3-0.21.41.41.1
Cocaine response after cond. corrected0.30.41.4-1.2-1.2-0.8-0.4-0.3-0.4-0.3-0.9-0.5-0.5-0.4-0.7-0.5-0.4-0.7-0.0-0.2-0.3
Cocaine response after cond. not corrected0.30.41.4-1.0-1.2-0.8-0.6-0.6-0.5-0.5-0.5-0.6-0.6-0.5-0.5-0.6-0.4-0.3-0.3-0.4-0.4
Cocaine response before conditioning0.20.21.11.00.60.4-0.2-0.20.0-0.11.00.10.1-0.00.70.20.40.9-0.4-0.30.2
Saline control response1.21.64.92.21.91.81.30.91.31.11.31.41.41.01.21.10.90.90.30.70.7
Bone: connectivity density1.21.88.91.51.90.4-0.4-0.7-0.7-0.63.0-0.4-0.4-0.7-0.4-0.7-1.12.8-1.5-1.2-1.2
Bone: cortical apparent density0.50.71.10.50.40.81.01.00.80.9-0.60.80.80.90.70.91.0-0.51.00.90.8
Bone: cortical area0.60.91.91.41.01.10.80.91.00.90.21.01.00.81.31.00.8-0.10.60.81.0
Bone: cortical porosity0.20.20.80.10.3-0.2-0.4-0.3-0.3-0.50.9-0.2-0.2-0.5-0.6-0.5-0.60.6-0.7-0.4-0.7
Bone: cortical porosity0.10.10.70.40.70.2-0.00.10.0-0.10.80.10.1-0.2-0.4-0.2-0.40.6-0.3-0.1-0.5
Bone: cortical thickness4.98.110.42.92.53.23.13.23.13.1-0.73.13.13.03.13.12.9-1.22.72.92.8
Bone: cortical thickness2.52.94.31.21.01.82.11.92.01.9-1.01.91.92.01.31.71.9-1.21.91.81.5
Bone: cortical tissue density0.70.91.40.70.61.01.21.11.01.1-0.61.01.01.10.81.01.2-0.51.11.00.9
Condit. Reinf. active minus inactive responses0.10.10.80.50.40.10.0-0.20.2-0.30.90.20.2-0.10.1-0.10.10.7-0.6-0.4-0.3
Condit. Reinf. active-inactive response ratio0.10.10.40.20.2-0.1-0.1-0.30.1-0.40.6-0.0-0.0-0.30.0-0.20.00.7-0.5-0.5-0.2
Condit. Reinf. active responses0.10.10.40.40.30.10.1-0.20.1-0.20.70.20.2-0.10.1-0.1-0.00.5-0.4-0.3-0.2
Condit. Reinf. inactive responses0.00.00.1-0.1-0.2-0.2-0.2-0.2-0.3-0.10.2-0.1-0.1-0.1-0.2-0.3-0.3-0.0-0.3-0.1-0.3
Incentive salience index mean0.10.21.00.60.70.20.1-0.10.1-0.21.00.20.2-0.10.0-0.2-0.20.8-0.6-0.3-0.4
Condit. Reinf. lever presses0.20.20.90.90.90.50.30.30.30.30.70.40.40.30.60.30.00.5-0.20.20.2
Condit. Reinf. active minus inactive responses1.11.52.6-0.3-0.6-1.1-1.6-1.6-1.3-1.41.2-1.3-1.3-1.4-0.3-1.1-0.91.3-1.6-1.5-0.9
Condit. Reinf. active-inactive response ratio1.61.83.5-0.8-1.2-1.4-1.9-1.8-1.5-1.60.7-1.5-1.5-1.5-0.5-1.2-1.00.9-1.6-1.6-0.9
Condit. Reinf. active responses1.21.73.60.10.1-0.8-1.5-1.5-1.3-1.41.9-1.2-1.2-1.5-0.4-1.2-1.11.7-1.7-1.6-1.2
Condit. Reinf. inactive responses0.40.52.30.40.90.0-0.3-0.3-0.5-0.51.5-0.3-0.3-0.7-0.5-0.7-0.71.1-0.7-0.6-1.0
Condit. Reinf. lever presses0.60.83.81.71.60.8-0.10.20.1-0.32.00.30.3-0.20.90.20.11.6-0.7-0.20.0
Condit. Reinf. lever reinforcers received0.91.33.70.40.3-0.5-1.3-1.2-1.0-1.21.9-1.0-1.0-1.3-0.1-1.0-0.91.7-1.5-1.3-1.0
Conditioned reinforcement - actives0.00.10.60.20.20.1-0.10.0-0.10.1-0.20.00.00.10.80.30.4-0.10.10.10.6
Conditioned reinforcement - inactives1.31.93.4-1.7-1.3-1.8-1.7-1.5-1.7-1.6-0.4-1.6-1.6-1.5-1.0-1.3-0.9-0.2-1.1-1.3-0.7
Conditioned locomotion3.04.09.9-3.1-3.1-2.7-2.2-2.1-1.9-2.0-1.7-2.0-2.0-1.8-1.7-1.6-1.5-1.7-0.9-1.2-0.9
Patch foraging indifference point 0 sec0.30.51.5-0.4-0.7-0.7-0.9-1.2-0.5-0.80.5-0.7-0.7-0.8-0.3-0.7-0.70.3-0.9-1.0-0.6
Patch foraging indifference point AUC1.42.04.12.02.01.81.31.81.21.40.51.21.21.31.61.51.40.71.21.11.2
Delay disc. indifference point, 0s delay1.11.23.2-1.3-1.2-1.1-0.8-1.1-0.9-1.10.2-0.8-0.8-1.0-1.8-1.3-1.5-0.1-0.9-0.9-1.4
Delay disc. indifference point, 16s delay1.41.62.5-1.0-1.1-1.3-1.5-1.6-1.3-1.50.6-1.3-1.3-1.3-1.2-1.3-1.00.7-1.5-1.5-1.1
Delay disc. indifference point, 2s delay0.50.50.8-0.6-0.8-0.8-0.8-0.9-0.6-0.80.4-0.7-0.7-0.7-0.7-0.8-0.80.2-0.9-0.8-0.7
Delay disc. indifference point, 24s delay0.20.20.6-0.3-0.30.20.60.10.50.4-0.70.50.50.5-0.10.30.3-0.60.30.40.2
Delay disc. indifference point, 4s delay0.40.51.4-0.7-0.7-0.6-0.3-0.7-0.6-0.60.2-0.3-0.3-0.5-1.2-0.8-1.00.3-0.7-0.6-1.0
Delay disc. indifference point, 8s delay0.30.30.8-0.5-0.6-0.5-0.2-0.9-0.5-0.50.2-0.3-0.3-0.3-0.9-0.6-0.70.2-0.8-0.5-0.8
Indifference point function ln k2.64.514.9-3.6-3.9-2.7-1.8-2.0-1.4-1.8-2.2-1.6-1.6-1.5-2.2-1.8-1.7-2.4-0.8-1.0-1.2
Indifference point function log k2.64.514.9-3.6-3.9-2.7-1.8-2.0-1.4-1.8-2.2-1.6-1.6-1.5-2.2-1.8-1.7-2.4-0.8-1.0-1.2
Patch foraging total patch changes 0 sec0.00.10.3-0.2-0.5-0.2-0.2-0.60.2-0.2-0.1-0.1-0.1-0.20.1-0.1-0.1-0.3-0.1-0.30.0
Patch foraging total patch changes 12 sec1.52.06.22.52.51.91.31.41.01.31.61.11.10.91.41.20.81.40.60.70.7
Patch foraging total patch changes 18 sec0.20.21.40.80.90.50.10.10.00.11.00.00.0-0.00.40.10.11.2-0.1-0.3-0.1
Patch foraging total patch changes 24 sec1.01.73.11.81.31.71.41.21.41.50.31.31.31.41.71.41.30.31.11.01.2
Patch foraging total patch changes 6 sec0.30.52.31.31.50.90.50.40.50.41.30.40.40.20.70.40.41.10.1-0.00.0
Patch foraging time to switch 0 sec0.71.47.31.31.60.4-0.2-0.6-0.6-0.42.7-0.3-0.3-0.6-0.4-0.6-0.92.6-1.3-1.0-1.1
Patch foraging water rate 0 sec0.91.99.3-2.2-2.7-1.2-0.4-0.20.1-0.1-3.0-0.4-0.40.10.10.10.3-2.90.90.50.8
Patch foraging water rate 12 sec1.83.815.7-3.6-4.0-2.0-0.8-0.7-0.4-0.6-3.9-0.8-0.8-0.2-1.3-0.6-0.5-3.80.80.40.2
Patch foraging water rate 18 sec0.81.25.7-2.0-2.4-1.2-0.4-0.7-0.1-0.5-2.0-0.5-0.5-0.2-0.8-0.4-0.3-1.90.20.1-0.0
Patch foraging water rate 24 sec1.21.78.7-2.3-2.4-1.2-0.2-0.00.0-0.1-2.9-0.4-0.40.1-0.6-0.10.1-2.70.80.60.5
Patch foraging water rate 6 sec1.42.09.6-2.2-2.8-1.0-0.0-0.10.40.0-3.10.20.20.3-0.20.10.1-3.11.00.80.7
Seeking ratio, delayed vs. immediate footshock0.70.91.8-0.5-0.6-0.8-0.8-1.3-0.8-1.00.9-0.6-0.6-0.9-1.0-1.1-1.00.9-1.3-1.1-1.1
Distance traveled before self-admin0.30.31.50.60.80.0-0.5-0.5-0.4-0.31.2-0.4-0.4-0.4-0.0-0.3-0.31.1-0.8-0.6-0.3
Distance traveled after self-admin0.10.10.50.50.70.2-0.20.0-0.10.00.6-0.0-0.0-0.10.40.00.30.4-0.3-0.20.1
Extensor digitorum longus weight4.216.734.75.95.95.34.54.24.24.02.04.64.63.94.13.93.51.42.63.32.9
Bone: elastic displacement1.41.64.7-0.4-0.50.51.21.11.21.2-2.21.01.01.30.71.11.3-2.11.61.31.3
Bone: elastic work2.63.44.91.51.22.02.22.02.12.2-1.02.02.02.21.71.91.9-1.11.91.91.8
Bone: endosteal estimation2.24.76.3-1.8-1.7-2.3-2.4-2.4-2.2-2.41.1-2.1-2.1-2.3-2.3-2.4-2.51.0-2.5-2.3-2.2
Bone: endosteal perimeter3.77.812.0-1.9-2.2-2.9-3.4-3.5-2.9-3.21.7-2.8-2.8-3.1-2.3-3.0-2.81.6-3.3-3.2-2.6
Epididymis fat weight1.96.713.0-3.6-3.5-3.4-3.1-2.6-2.6-2.8-1.3-3.0-3.0-2.5-2.3-2.4-2.3-1.2-1.6-2.0-1.5
Delta time in closed arm before/after self-admin1.00.92.10.41.11.01.51.31.01.3-0.61.01.01.10.30.70.5-0.71.11.10.4
Delta time in open arm before/after self-admin0.10.10.60.60.80.2-0.20.3-0.1-0.00.5-0.2-0.2-0.10.50.20.40.7-0.0-0.00.3
Diff in mean of infusions in LGA sessions0.50.61.31.11.21.00.80.80.80.90.20.60.60.71.00.90.60.60.60.50.7
Delay discount exponential model param0.40.51.20.50.50.50.51.10.50.7-0.60.40.40.50.90.80.7-0.51.10.80.9
Extinction: sum of active levers before priming0.70.73.11.71.30.90.30.10.30.31.80.30.30.10.80.3-0.11.8-0.5-0.2-0.0
Active lever presses in extinction session 61.91.97.12.12.71.61.01.31.31.20.91.11.11.01.91.21.40.90.70.91.1
Bone: final force0.81.33.71.91.81.51.11.11.01.01.01.31.31.01.21.00.80.50.40.80.7
Bone: final moment0.71.23.41.81.71.41.01.01.00.91.01.31.30.91.10.90.70.40.30.70.7
Food consumed during 24 hour testing period0.20.20.80.30.20.30.10.60.40.2-0.40.20.20.20.90.60.7-0.40.30.50.8
Glucose3.85.98.4-2.5-2.1-2.7-2.6-2.8-2.6-2.70.8-2.4-2.4-2.6-2.9-2.7-2.50.8-2.4-2.5-2.6
Heart weight2.64.17.4-1.9-1.1-2.0-1.7-1.8-2.3-2.11.0-2.0-2.0-2.1-2.7-2.4-2.60.9-2.0-1.9-2.6
Delay discount hyperbolic model param0.50.61.20.50.60.60.61.10.60.8-0.60.40.40.61.00.80.8-0.51.10.91.0
Intermittent access intake day 1-15 change0.20.41.1-1.1-0.9-0.9-0.7-0.6-0.6-0.7-0.9-0.7-0.7-0.6-0.1-0.3-0.2-0.7-0.1-0.40.1
Intermittent access intake escalation0.10.30.8-0.8-0.8-0.7-0.6-0.4-0.4-0.5-0.9-0.5-0.5-0.40.2-0.10.1-0.60.1-0.20.3
Intermittent access intake escalation 20.30.30.9-0.9-0.8-0.8-0.7-0.4-0.4-0.5-1.0-0.6-0.6-0.40.0-0.20.1-0.70.0-0.20.3
Intermitt. access day 1 inactive lever presses0.00.10.1-0.2-0.3-0.3-0.3-0.3-0.2-0.3-0.0-0.3-0.3-0.3-0.1-0.20.10.2-0.1-0.3-0.0
Intermitt. access day 15 inactive lever presses0.81.72.7-1.2-1.3-1.6-1.6-1.6-1.5-1.60.3-1.4-1.4-1.6-0.9-1.3-0.90.6-1.3-1.5-1.0
Intermitt. access escalation Index2.12.96.1-2.4-2.5-2.1-1.7-1.6-1.7-1.7-0.7-1.7-1.7-1.6-2.0-1.7-1.8-0.9-1.1-1.2-1.5
Intermittent access day 1 total infusions4.67.410.7-2.2-1.3-2.8-2.9-3.0-3.3-2.91.5-2.9-2.9-2.9-2.9-3.0-3.01.5-3.0-2.9-2.9
Intermittent access day 15 total infusions3.34.97.4-2.5-1.9-2.7-2.7-2.6-2.7-2.5-0.0-2.6-2.6-2.4-1.9-2.2-2.00.2-2.0-2.1-1.7
Intermittent access terminal intake (last 3 days)4.15.48.2-2.3-1.5-2.7-2.8-2.7-2.9-2.70.5-2.7-2.7-2.6-2.0-2.4-2.10.7-2.3-2.4-2.0
Intermittent access total infusions4.65.48.0-2.1-1.2-2.6-2.6-2.7-2.8-2.60.9-2.6-2.6-2.6-2.2-2.5-2.41.1-2.5-2.4-2.3
Intermittent access day 1 locomotion3.54.46.4-1.8-1.1-2.2-2.2-2.4-2.5-2.31.1-2.2-2.2-2.3-2.2-2.4-2.21.1-2.3-2.3-2.3
Intermittent access day 15 total locomotion2.85.17.7-2.3-2.0-2.7-2.7-2.7-2.8-2.60.4-2.6-2.6-2.6-1.8-2.3-2.00.5-2.1-2.3-1.8
Intermittent access total locomotion7.89.413.4-3.0-2.2-3.5-3.6-3.6-3.7-3.60.9-3.3-3.3-3.5-2.8-3.2-3.00.9-3.1-3.2-2.7
Intermittent access standard deviation0.20.41.4-1.2-0.8-0.9-0.6-0.5-0.5-0.6-0.8-0.6-0.6-0.5-0.4-0.5-0.3-0.7-0.1-0.2-0.1
Left kidney weight0.42.04.6-2.1-2.1-1.8-1.4-1.1-1.5-1.2-1.0-1.4-1.4-1.2-1.5-1.3-1.7-1.1-0.7-0.7-1.0
Right kidney weight0.20.73.3-1.4-1.8-0.9-0.6-0.4-0.4-0.4-1.4-0.5-0.5-0.3-0.3-0.3-0.7-1.50.20.00.1
Cocaine induced anxiety0.00.00.20.30.40.0-0.2-0.0-0.1-0.10.3-0.0-0.0-0.10.1-0.00.30.4-0.2-0.10.1
Post-drug Anxiety0.30.31.01.00.90.70.30.50.40.50.50.50.50.40.80.50.60.40.20.30.5
Baseline Anxiety0.40.40.60.60.40.80.70.70.70.8-0.30.60.60.80.80.70.5-0.60.70.70.6
Tail length1.03.95.81.51.12.12.42.32.32.3-1.22.32.32.21.62.11.7-1.22.22.21.9
Length with tail1.98.311.63.12.83.43.33.33.33.2-0.33.43.43.02.73.02.7-0.52.72.82.6
Length without tail2.06.48.82.82.63.02.82.82.82.7-0.13.03.02.62.52.62.8-0.42.32.42.3
Times rat made contact with spout0.10.20.80.60.70.40.40.10.40.20.70.30.30.2-0.00.1-0.10.9-0.2-0.1-0.2
Lifetime Intake3.34.16.3-1.8-0.9-2.2-2.2-2.3-2.5-2.20.9-2.3-2.3-2.2-2.0-2.2-2.21.0-2.1-2.0-2.1
Liver weight, left0.40.63.1-1.2-1.2-0.40.30.40.10.4-1.70.10.10.4-0.70.10.0-1.80.70.50.1
Liver weight, right0.71.24.5-2.1-2.1-1.2-0.4-0.5-0.5-0.4-1.6-0.4-0.4-0.3-1.4-0.7-0.5-1.9-0.1-0.1-0.6
Locomotor activity0.60.95.1-1.5-1.5-0.60.2-0.00.50.2-2.20.20.20.4-0.20.10.3-2.30.80.60.4
Locomotor testing distance0.71.26.6-1.8-1.9-0.70.2-0.10.40.2-2.40.20.20.4-0.70.00.3-2.60.80.70.3
Locomotor testing rearing0.61.24.3-2.1-1.7-1.4-0.8-1.0-0.8-0.8-1.3-0.8-0.8-0.7-1.7-1.0-0.7-1.3-0.3-0.4-0.8
Locomotion in novel chamber2.83.67.7-2.8-2.6-2.5-2.1-2.2-1.9-2.0-1.1-1.9-1.9-1.8-1.8-1.8-1.5-1.1-1.2-1.4-1.2
Locomotion in novel chamber post-restriction1.32.14.3-2.1-1.6-1.9-1.7-1.5-1.6-1.6-0.7-1.7-1.7-1.4-1.4-1.4-1.1-0.7-0.9-1.1-1.0
Fecal boli incidents, locomotor time 10.10.10.40.20.6-0.0-0.30.3-0.3-0.10.2-0.4-0.4-0.10.60.10.50.60.1-0.10.2
Change in fecal boli incidents, locomotor task0.20.20.6-0.3-0.5-0.2-0.0-0.80.1-0.30.2-0.0-0.0-0.2-0.6-0.4-0.7-0.1-0.4-0.4-0.6
Time >=10cm from walls, locomotor time 13.63.86.1-1.1-1.0-1.9-2.2-2.4-2.5-2.31.5-1.9-1.9-2.2-1.6-2.0-1.71.4-2.4-2.3-1.8
Bouts of movement, locomotor time 10.70.82.01.41.41.10.80.80.60.80.60.80.80.71.30.91.11.10.50.30.8
Total resting periods, locomotor time 10.40.51.61.11.10.70.30.40.30.30.80.40.40.31.00.60.81.30.1-0.10.5
Rest time, locomotor task time 10.60.73.1-1.3-1.8-1.1-1.0-1.1-0.6-0.8-0.9-0.7-0.7-0.6-0.5-0.5-0.1-0.8-0.4-0.6-0.1
Distance moved, locomotor task time 10.30.51.70.20.6-0.2-0.4-0.6-0.7-0.71.3-0.4-0.4-0.7-0.7-0.7-0.90.9-0.9-0.6-1.0
Vertical activity count, locomotor time 10.10.30.9-0.9-0.7-0.7-0.3-0.5-0.5-0.5-0.5-0.6-0.6-0.5-0.7-0.5-0.7-0.3-0.2-0.3-0.5
Time >=10cm from walls, locomotor time 20.10.10.40.1-0.1-0.3-0.4-0.7-0.3-0.40.4-0.3-0.3-0.30.1-0.2-0.10.3-0.6-0.5-0.0
Bouts of movement, locomotor time 20.20.31.20.81.10.60.40.70.30.40.70.20.20.20.30.20.40.80.10.10.1
Total resting periods, locomotor time 20.10.10.70.50.80.20.00.4-0.10.00.7-0.1-0.1-0.10.0-0.10.10.8-0.1-0.2-0.2
Rest time, locomotor task time 21.01.33.3-1.8-1.8-1.5-1.1-1.0-1.4-1.1-0.9-1.1-1.1-1.0-1.3-1.0-0.8-0.7-0.5-0.7-0.8
Distance moved, locomotor task time 20.70.82.01.41.11.21.00.51.00.90.51.11.10.81.11.00.70.30.40.60.8
Vertical activity count, locomotor time 21.21.72.60.50.11.11.51.21.61.5-1.41.31.31.51.11.41.1-1.31.51.41.4
Light reinforcement 10.00.10.7-0.5-0.8-0.3-0.2-0.3-0.10.1-0.4-0.1-0.10.1-0.3-0.1-0.1-0.4-0.1-0.1-0.0
Light reinforcement 20.40.62.1-0.9-1.4-1.0-1.2-0.9-0.5-0.8-0.3-0.9-0.9-0.8-0.2-0.6-0.4-0.1-0.7-0.7-0.2
Bone: marrow area2.35.06.9-1.9-1.8-2.4-2.5-2.5-2.3-2.51.1-2.2-2.2-2.4-2.4-2.5-2.61.0-2.5-2.4-2.3
Bone: maximum diameter0.10.10.50.5-0.1-0.0-0.5-0.3-0.0-0.20.5-0.1-0.1-0.30.70.1-0.00.4-0.5-0.40.3
Bone: maximum force0.81.46.32.22.11.10.20.10.40.12.50.60.60.10.90.30.22.1-0.8-0.4-0.0
Bone: maximum moment0.71.25.82.12.01.10.20.00.40.12.40.60.60.10.80.20.22.0-0.8-0.4-0.1
Mean time between licks in bursts0.20.51.00.50.30.70.90.71.00.9-0.30.90.90.90.40.60.6-0.30.60.80.5
Mean num. licks in bursts0.10.20.8-0.7-0.4-0.4-0.2-0.2-0.5-0.5-0.2-0.4-0.4-0.5-0.9-0.5-0.8-0.1-0.1-0.2-0.6
Cd content in liver1.01.21.9-1.2-1.4-1.3-1.4-1.3-1.1-1.2-0.1-1.4-1.4-1.0-0.9-1.0-0.80.3-0.8-1.1-0.7
Co content in liver1.51.77.5-1.0-1.40.11.00.90.91.0-2.60.80.81.10.30.81.2-2.71.61.41.1
Cu content in liver0.10.20.3-0.1-0.1-0.3-0.4-0.4-0.4-0.60.6-0.4-0.4-0.5-0.3-0.5-0.40.3-0.5-0.3-0.5
Fe content in liver0.40.50.90.50.40.80.80.90.90.9-0.40.60.60.80.60.80.9-0.50.80.80.7
K content in liver0.10.10.60.50.70.30.20.00.1-0.10.80.30.30.1-0.2-0.10.00.6-0.3-0.1-0.3
Mg content in liver0.50.51.0-0.8-0.7-0.8-0.7-0.8-0.6-0.90.3-0.6-0.6-0.7-1.0-0.9-0.40.1-0.7-0.7-0.9
Mn content in liver1.51.75.32.32.31.61.01.01.00.91.41.01.00.81.51.11.41.60.40.60.9
Na content in liver0.90.92.00.8-0.00.90.70.71.20.9-0.60.90.91.01.41.21.3-0.60.90.81.3
Rb content in liver1.51.73.0-1.7-1.3-1.6-1.3-1.3-1.3-1.5-0.1-1.4-1.4-1.3-1.7-1.5-1.1-0.2-1.0-1.2-1.4
Se content in liver0.40.50.9-0.3-0.3-0.6-0.9-0.7-0.8-1.00.6-0.9-0.9-0.9-0.3-0.6-0.70.6-0.7-0.7-0.5
Sr content in liver2.52.23.11.81.81.71.51.61.61.5-0.11.51.51.51.71.61.60.11.31.31.5
Zn content in liver0.10.10.30.50.60.50.50.50.40.20.20.40.40.30.20.3-0.10.10.30.40.1
Bone: minimum diameter3.15.78.2-1.5-1.3-2.3-2.6-2.7-2.4-2.71.8-2.3-2.3-2.6-2.4-2.6-2.61.8-2.9-2.8-2.5
Time in familiar zone, hab. session 10.70.71.3-0.5-0.4-0.9-1.0-1.1-0.8-1.00.6-0.8-0.8-0.8-0.6-0.9-0.40.5-1.0-1.1-0.8
Time in novel zone, hab. session 10.40.41.4-0.4-0.30.20.60.70.60.6-1.20.50.50.50.00.50.2-1.10.80.80.5
Total zone transitions, hab. session 10.20.31.11.01.00.70.50.30.40.20.90.70.70.40.50.30.20.5-0.10.20.1
Total locomotion distance, hab. session 10.30.40.8-0.7-0.9-0.8-0.7-0.8-0.7-0.70.1-0.6-0.6-0.6-0.6-0.7-0.70.0-0.7-0.7-0.7
Locomotion velocity, hab. session 10.10.10.2-0.2-0.4-0.3-0.3-0.4-0.3-0.30.2-0.2-0.2-0.2-0.2-0.4-0.50.1-0.4-0.4-0.4
Time in familiar zone, hab. session 20.50.51.10.10.40.60.90.90.80.8-0.80.70.70.80.20.71.0-0.81.00.80.6
Time in novel zone, hab. session 20.60.61.4-0.1-0.4-0.5-0.8-0.9-0.7-0.91.0-0.6-0.6-0.9-0.5-0.7-1.20.9-1.0-0.9-0.8
Total zone transitions, hab. session 21.72.28.00.60.9-0.4-1.0-1.4-1.2-1.32.8-0.8-0.8-1.2-1.2-1.4-1.32.5-1.9-1.7-1.8
Total locomotion distance, hab. session 21.31.72.9-0.6-0.5-1.1-1.2-1.6-1.3-1.31.4-1.1-1.1-1.2-1.4-1.5-1.31.3-1.6-1.6-1.7
Locomotion velocity, hab. session 21.62.23.5-0.8-0.8-1.3-1.4-1.9-1.5-1.51.4-1.3-1.3-1.4-1.5-1.7-1.41.4-1.8-1.8-1.8
Novel to familiar place preference ratio0.40.42.11.00.80.2-0.5-0.4-0.3-0.11.4-0.4-0.4-0.40.5-0.1-0.21.5-0.6-0.6-0.1
Novelty place preference0.40.51.90.50.4-0.1-0.7-0.7-0.6-0.31.2-0.7-0.7-0.70.1-0.3-0.41.4-0.8-0.8-0.3
Time in novel zone, NPP test0.40.41.50.40.3-0.2-0.7-0.7-0.6-0.31.1-0.7-0.7-0.70.0-0.4-0.51.2-0.7-0.8-0.4
Total zone transitions, NPP test0.40.62.71.41.40.90.40.10.30.21.70.70.70.30.40.20.01.1-0.4-0.1-0.2
Total locomotion distance, NPP test0.10.20.4-0.1-0.2-0.2-0.2-0.6-0.2-0.40.5-0.0-0.0-0.2-0.4-0.5-0.60.1-0.6-0.4-0.6
Locomotion velocity, NPP test0.10.10.30.0-0.2-0.2-0.2-0.5-0.2-0.30.60.00.0-0.1-0.3-0.4-0.60.2-0.6-0.4-0.5
Intraocular pressure0.20.31.3-0.8-1.1-0.5-0.30.0-0.40.0-1.1-0.5-0.5-0.10.10.10.4-0.70.50.10.5
Delta distance traveled before/after self-admin0.20.30.7-0.1-0.20.20.50.60.40.5-0.80.30.30.50.30.40.5-0.80.70.60.5
Delta ambulatory time before/after self-admin0.20.30.60.0-0.10.40.60.70.50.6-0.70.50.50.50.40.50.6-0.80.80.60.5
Parametrial fat weight2.45.610.6-3.3-2.9-3.0-2.5-2.2-2.9-2.1-0.8-2.7-2.7-2.5-2.7-2.4-2.3-0.6-1.6-1.8-2.0
Pavlov. Cond. lever latency0.10.10.3-0.5-0.6-0.4-0.2-0.4-0.0-0.2-0.4-0.2-0.2-0.1-0.0-0.1-0.2-0.4-0.1-0.10.0
Pavlov. Cond. magazine entry latency0.60.82.10.20.6-0.5-0.9-0.9-0.7-1.01.5-0.6-0.6-0.9-0.5-0.8-0.71.4-1.3-0.9-0.9
Pavlov. Cond. change in total contacts0.40.51.30.30.3-0.4-0.9-0.6-0.7-0.71.1-0.6-0.6-0.80.1-0.5-0.41.2-0.9-0.8-0.4
Pavlov. Cond. index score0.10.10.30.40.50.1-0.2-0.0-0.1-0.20.50.10.1-0.10.20.00.10.5-0.2-0.10.1
Pavlov. Cond. latency score0.10.10.30.20.3-0.0-0.3-0.1-0.3-0.30.5-0.1-0.1-0.2-0.1-0.2-0.10.5-0.3-0.2-0.2
Pavlov. Cond. lever contacts0.00.00.10.20.30.0-0.10.1-0.2-0.10.4-0.0-0.0-0.2-0.2-0.1-0.10.2-0.2-0.0-0.2
Pavlov. Cond. magazine entry number0.10.10.6-0.7-0.8-0.30.1-0.1-0.20.0-0.5-0.3-0.3-0.1-0.5-0.2-0.4-0.50.1-0.1-0.4
Pavlov. Cond. intertrial magazine entries0.10.10.6-0.3-0.8-0.1-0.10.2-0.00.1-0.6-0.2-0.20.00.40.20.0-0.70.30.20.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.60.70.2-0.2-0.0-0.1-0.20.70.10.1-0.10.2-0.0-0.00.6-0.3-0.1-0.0
Pavlov. Cond. response bias0.10.10.50.60.70.30.00.20.20.10.30.30.30.10.50.30.40.3-0.00.20.3
Pavlov. Cond. lever latency0.30.41.0-1.0-0.9-0.7-0.3-0.7-0.4-0.4-0.5-0.6-0.6-0.3-0.9-0.6-0.5-0.1-0.3-0.6-0.6
Pavlov. Cond. magazine entry latency1.41.76.72.42.61.40.60.50.70.62.40.90.90.41.10.50.62.4-0.4-0.10.1
Pavlov. Cond. change in total contacts0.60.94.41.61.40.5-0.5-0.3-0.3-0.32.1-0.0-0.0-0.51.0-0.00.22.1-0.9-0.5-0.1
Pavlov. Cond. index score0.81.03.81.91.91.10.30.40.40.31.90.60.60.21.10.50.51.7-0.40.00.3
Pavlov. Cond. latency score0.70.93.41.81.81.00.30.40.40.41.70.70.70.31.10.50.51.6-0.30.10.3
Pavlov. Cond. lever contacts0.20.31.01.00.90.60.20.60.20.30.60.40.40.20.80.50.40.40.10.40.4
Pavlov. Cond. magazine entry number2.32.89.9-3.1-3.1-1.9-0.9-0.8-1.0-0.9-2.7-1.2-1.2-0.7-1.8-0.9-1.1-2.70.3-0.2-0.5
Pavlov. Cond. intertrial magazine entries0.50.72.6-1.3-1.6-1.1-0.8-0.8-0.6-0.7-0.8-0.9-0.9-0.6-0.7-0.7-0.6-0.6-0.3-0.6-0.4
Pavlov. Cond. lever-magazine prob. diff.0.91.24.62.12.11.20.40.50.50.42.00.70.70.31.20.50.61.9-0.30.00.3
Pavlov. Cond. response bias0.60.83.01.71.71.00.30.50.30.31.70.60.60.11.00.40.51.5-0.30.10.2
Time in closed arm before self-admin1.01.32.4-0.7-0.7-1.2-1.5-1.6-1.2-1.50.7-1.1-1.1-1.2-0.9-1.1-0.90.9-1.4-1.3-0.9
Time in closed arm after self-admin0.10.10.2-0.40.0-0.4-0.2-0.3-0.2-0.3-0.1-0.1-0.1-0.1-0.4-0.3-0.10.0-0.2-0.3-0.3
Time in open arm before self-admin0.70.82.7-0.5-0.50.51.20.71.01.0-1.40.90.91.0-0.10.50.2-1.61.01.10.3
Time in open arm after self-admin0.20.30.60.20.60.50.60.80.60.7-0.40.40.40.50.20.50.4-0.40.60.80.4
Bone: periosteal estimation0.20.51.1-0.2-0.4-0.6-0.9-0.8-0.6-0.80.7-0.6-0.6-0.8-0.4-0.7-0.90.5-1.1-0.8-0.6
Bone: periosteal perimeter0.50.82.00.2-0.2-0.6-1.2-1.2-0.8-1.01.4-0.7-0.7-1.0-0.1-0.8-0.81.1-1.4-1.2-0.7
Bone: post-yield work6.29.119.70.10.3-1.9-3.0-3.3-2.8-3.14.3-2.6-2.6-3.1-1.9-2.9-3.04.4-3.9-3.8-3.1
Progressive ratio test 1 active lever presses0.30.30.8-0.3-0.1-0.5-0.6-0.7-0.9-0.50.4-0.7-0.7-0.5-0.3-0.6-0.60.4-0.7-0.6-0.6
Progressive ratio test 1 breakpoint0.20.30.7-0.20.0-0.4-0.5-0.7-0.9-0.40.5-0.7-0.7-0.5-0.2-0.5-0.50.4-0.7-0.6-0.5
Progressive ratio test 1 inactive lever presses0.10.20.3-0.20.1-0.3-0.4-0.4-0.5-0.40.3-0.5-0.5-0.5-0.1-0.4-0.40.4-0.5-0.5-0.3
Progressive ratio test 2 active lever presses2.12.43.8-1.5-1.3-1.8-1.8-1.9-1.9-1.70.4-1.9-1.9-1.7-1.2-1.6-1.40.5-1.6-1.6-1.3
Progressive ratio test 2 breakpoint1.92.23.4-1.4-1.2-1.7-1.8-1.8-1.8-1.60.3-1.8-1.8-1.6-1.1-1.5-1.30.5-1.5-1.5-1.1
Progressive ratio test 2 inactive lever presses4.67.411.4-3.2-2.7-3.4-3.2-3.1-3.2-3.1-0.2-3.1-3.1-3.0-2.6-2.8-2.5-0.0-2.4-2.6-2.2
Incentive Sensitization - Responses0.60.81.9-0.1-0.0-0.6-0.9-1.0-0.9-1.01.2-0.9-0.9-1.0-0.4-0.8-0.81.4-1.1-1.0-0.8
Incentive Sensitization - Breakpoint0.70.91.5-0.3-0.2-0.8-1.0-1.1-0.9-1.11.0-1.0-1.0-1.1-0.5-0.9-0.81.2-1.1-1.1-0.9
Sum of active levers in priming session hrs 5-63.23.08.61.81.21.71.31.61.61.6-0.61.51.51.52.92.12.3-0.51.51.52.4
Progressive ratio1.21.96.30.51.3-0.4-0.8-1.0-1.2-1.12.5-0.9-0.9-1.3-1.1-1.3-1.42.3-1.6-1.5-1.7
Food seeking constrained by brief footshock0.10.20.40.40.10.50.60.40.50.5-0.00.50.50.40.30.40.2-0.00.50.40.3
Seeking ratio, punishment vs. effort0.91.35.4-0.9-1.70.10.70.60.90.8-2.30.70.71.00.40.80.8-2.21.31.11.1
Retroperitoneal fat weight5.021.247.8-6.9-6.7-6.0-4.9-4.5-4.4-4.5-2.7-4.8-4.8-4.3-4.9-4.4-4.4-2.6-2.8-3.1-3.3
Reaction time number correct0.51.01.70.70.60.90.91.01.11.0-0.61.01.01.01.31.11.3-0.61.11.01.2
Reaction time mean minus median0.71.85.52.32.31.61.00.91.01.11.51.11.10.91.71.11.11.60.30.50.8
Reaction time mean minus median AUC0.71.93.51.91.71.71.41.21.31.50.51.41.41.31.61.41.60.71.11.11.2
Reaction time num false alarms0.60.82.8-0.4-0.50.41.00.71.01.0-1.50.80.81.10.10.70.6-1.71.10.90.7
Reaction time num false alarms AUC0.81.22.00.30.20.91.41.01.41.3-1.11.31.31.40.41.01.1-1.31.21.10.9
Reaction time trials correct on left0.51.01.70.70.60.90.91.01.11.0-0.61.01.01.01.31.11.3-0.61.11.01.2
Reaction time trials on left0.71.32.10.90.71.11.01.21.31.2-0.71.21.21.21.41.21.4-0.61.21.11.3
Reaction time mean0.00.00.20.20.30.0-0.1-0.2-0.2-0.10.4-0.0-0.0-0.10.0-0.00.10.5-0.1-0.1-0.0
Reaction time mean AUC0.10.10.50.10.2-0.1-0.3-0.4-0.3-0.30.5-0.2-0.2-0.3-0.1-0.2-0.10.7-0.3-0.3-0.2
Median of all reaction times0.20.30.4-0.5-0.3-0.6-0.6-0.6-0.7-0.60.2-0.5-0.5-0.5-0.6-0.5-0.40.3-0.5-0.5-0.5
Reaction time omissions1.11.63.71.91.91.71.41.31.01.50.71.31.31.21.21.21.30.60.81.00.9
Reaction time false alarm rate0.20.31.1-0.3-0.40.20.80.30.70.6-0.90.60.60.7-0.40.30.3-1.00.50.50.2
Reaction time premature initiation rate1.92.74.41.81.42.02.11.82.01.80.01.91.91.91.41.61.5-0.31.41.71.2
Reaction time premature initiations3.15.57.72.51.92.82.72.52.82.6-0.32.72.72.62.32.42.5-0.62.12.32.0
Std. dev. reaction times0.30.51.61.21.30.90.60.50.40.60.80.70.70.50.80.60.70.90.20.30.4
Reaction time trials completed0.71.32.10.90.71.11.01.21.31.2-0.71.21.21.21.41.21.4-0.61.21.11.3
Reaction time trials AUC0.51.01.70.70.50.90.91.01.11.0-0.71.01.01.01.21.11.3-0.61.11.01.1
Run reversals in cocaine runway, females0.20.20.60.30.80.20.3-0.00.0-0.10.80.30.3-0.1-0.6-0.3-0.40.7-0.20.0-0.7
Run reversals in cocaine runway, males1.92.04.7-0.0-0.10.81.31.31.31.3-2.01.21.21.41.11.41.6-2.21.81.71.6
Latency to leave start box in cocaine runway1.01.11.8-0.30.1-0.9-1.2-1.2-1.1-1.21.2-1.0-1.0-1.1-1.0-1.1-0.91.1-1.3-1.3-1.2
Latency to leave start box in cocaine runway, F0.50.60.9-0.3-0.1-0.6-0.8-0.9-0.8-0.80.9-0.7-0.7-0.8-0.8-0.8-0.80.8-0.9-1.0-0.9
Latency to leave start box in cocaine runway, M0.10.10.50.30.5-0.1-0.3-0.4-0.3-0.30.7-0.2-0.2-0.3-0.0-0.30.10.6-0.5-0.5-0.3
Std. dev. time between licks in bursts0.91.22.9-0.10.10.71.41.11.21.4-1.41.21.21.40.30.90.8-1.71.31.30.8
Total sessions with >9 infusions0.80.91.7-0.10.4-0.6-0.8-0.9-1.1-0.91.3-0.9-0.9-0.9-0.8-1.0-1.21.2-1.2-1.0-1.2
Short access day 1 total inactive lever presses1.31.73.3-1.8-1.6-1.6-1.4-1.1-1.5-1.4-0.5-1.5-1.5-1.3-1.4-1.3-1.4-0.6-0.9-0.9-1.0
Short access day 10 total inactive lever presses0.00.10.3-0.6-0.5-0.4-0.0-0.0-0.1-0.2-0.4-0.2-0.2-0.2-0.4-0.2-0.0-0.20.0-0.1-0.2
Short access day 1 total infusions2.02.74.1-1.6-0.9-1.8-1.8-1.6-2.0-1.80.5-1.8-1.8-1.8-1.7-1.9-2.00.5-1.6-1.5-1.8
Short access day 10 total infusions3.64.66.5-0.80.3-1.7-2.1-2.3-2.5-2.22.3-2.2-2.2-2.3-2.0-2.3-2.52.2-2.6-2.4-2.5
Short access total infusions1.62.03.5-0.8-0.1-1.2-1.3-1.4-1.8-1.41.3-1.5-1.5-1.5-1.5-1.6-1.91.2-1.7-1.4-1.8
Short access day 1 locomotion1.62.02.9-1.3-0.7-1.6-1.5-1.6-1.7-1.60.7-1.5-1.5-1.6-1.2-1.6-1.40.8-1.6-1.5-1.5
Short access day 10 total locomotion1.32.33.4-1.2-0.5-1.6-1.6-1.7-1.6-1.80.9-1.6-1.6-1.9-1.4-1.7-1.60.9-1.6-1.7-1.6
Short access total locomotion2.12.63.6-1.3-0.8-1.7-1.7-1.9-1.8-1.80.8-1.7-1.7-1.8-1.4-1.8-1.70.8-1.7-1.7-1.6
One hour access (0.3 mA shock)3.64.27.7-2.8-2.3-2.6-2.2-2.3-2.3-2.2-0.5-2.2-2.2-2.1-2.2-2.1-1.8-0.2-1.6-1.8-1.7
Compulsive drug intake3.44.16.61.50.82.22.62.42.42.4-1.12.32.32.41.32.12.0-1.22.12.31.7
One hour access (shock baseline)4.36.610.4-3.0-2.2-3.2-3.1-3.1-3.0-3.0-0.0-2.9-2.9-2.9-2.2-2.6-2.30.3-2.2-2.6-2.0
Social response proportion0.30.32.10.80.80.3-0.1-0.50.10.01.10.10.1-0.10.40.00.41.5-0.5-0.6-0.1
Social responses0.20.30.60.60.40.60.60.40.60.60.10.60.60.50.50.50.80.20.50.30.4
Social time0.40.50.80.70.50.80.90.70.90.8-0.20.90.90.70.60.80.7-0.20.70.80.6
Soleus weight1.44.214.2-3.7-3.8-2.6-1.6-1.4-1.4-1.6-2.7-1.8-1.8-1.3-2.1-1.5-1.6-2.5-0.4-0.7-0.9
Bone: stiffness0.71.26.71.71.70.5-0.4-0.3-0.3-0.42.6-0.1-0.1-0.50.3-0.3-0.32.3-1.2-0.8-0.5
Tibialis anterior weight8.127.644.66.76.46.45.75.65.55.50.85.85.85.35.85.45.20.14.14.74.6
Time to tail flick, vehicle, before self-admin0.10.10.60.20.6-0.0-0.1-0.2-0.2-0.20.8-0.1-0.1-0.2-0.0-0.4-0.10.6-0.5-0.4-0.5
Time to tail flick, vehicle, after self-admin0.40.62.00.31.0-0.1-0.1-0.5-0.4-0.41.4-0.2-0.2-0.4-0.9-0.7-1.01.3-1.0-0.6-1.1
Time to tail flick, test, before self-admin2.42.54.0-1.7-1.1-1.8-1.3-2.0-1.7-1.70.5-1.5-1.5-1.5-2.0-1.9-1.80.3-1.7-1.5-1.9
Time to tail flick, test, after self-admin0.00.00.30.20.6-0.0-0.1-0.1-0.2-0.00.2-0.1-0.10.10.40.00.30.2-0.1-0.10.2
Delta time to tail flick, vehicle, before/after SA0.20.21.00.40.70.10.1-0.3-0.1-0.10.9-0.0-0.0-0.1-0.5-0.3-0.51.0-0.6-0.3-0.5
Delta time to tail flick, test, before/after SA4.04.16.41.81.52.01.82.32.12.2-1.01.91.92.12.52.32.5-0.82.12.12.5
Tibia length0.72.04.22.01.31.71.11.21.41.50.21.31.31.42.01.71.60.21.01.11.8
Ambulatory time before self-admin0.40.72.30.50.8-0.2-0.8-0.8-0.7-0.61.5-0.6-0.6-0.8-0.1-0.5-0.31.5-1.1-1.0-0.5
Ambulatory time after self-admin1.11.32.3-0.5-0.1-1.1-1.5-1.3-1.4-1.31.0-1.2-1.2-1.4-0.8-1.2-0.80.9-1.4-1.4-1.0
Bone: tissue strength0.20.20.4-0.00.1-0.3-0.5-0.4-0.5-0.50.6-0.4-0.4-0.4-0.1-0.4-0.50.4-0.6-0.5-0.4
Total heroin consumption1.92.36.52.51.82.11.41.21.61.71.21.31.31.31.91.51.21.10.60.91.1
Bone: trabecular number1.32.17.40.71.4-0.3-1.1-1.1-1.2-1.22.7-1.0-1.0-1.4-0.8-1.2-1.42.5-1.9-1.5-1.5
Bone: trabecular spacing0.30.41.8-0.7-0.8-0.10.50.40.30.4-1.30.30.30.5-0.30.20.2-1.30.70.70.3
Bone: trabecular thickness1.62.03.0-0.8-0.4-1.3-1.6-1.4-1.4-1.71.3-1.5-1.5-1.6-1.3-1.6-1.41.3-1.7-1.6-1.5
Bone: trabecular tissue density1.11.66.3-2.3-2.5-1.7-1.0-0.9-0.7-0.9-2.0-0.9-0.9-0.6-0.8-0.7-0.5-1.9-0.1-0.2-0.0
Water consumed over 24 hours0.40.51.21.11.00.90.70.60.80.70.60.70.70.60.70.60.60.50.20.30.4
Number of responses in last shaping day0.10.10.3-0.00.30.30.40.60.20.5-0.50.30.30.50.20.30.3-0.50.50.60.2