Hub : Genes

LOC120095637

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	LOC120095637	0.11	0.06	1.5e-12	0.09	0.09	0.09	0.09	2.8e-10	3.6e-10	3.7e-10	9.0e-10
2	BLA	gene expression	LOC120095637	0.16	0.09	5.5e-06	0.08	0.1	0.08	0.09	3.6e-05	8.8e-06	3.9e-05	1.1e-05
3	PL	gene expression	LOC120095637	0.1	0.05	3.0e-10	0.08	0.1	0.1	0.1	3.1e-09	2.7e-11	1.0e-10	5.2e-11
4	Brain	gene expression	LOC120095637	0.13	0.07	1.0e-09	0.1	0.11	0.11	0.11	9.0e-10	2.8e-10	3.6e-10	4.7e-10
5	OFC	gene expression	LOC120095637	0.16	0.11	9.5e-03	0.02	0.08	0.01	0.09	1.2e-01	5.8e-03	1.9e-01	3.3e-03
6	NAcc	gene expression	LOC120095637	0.03	0.02	7.7e-04	0.03	0.03	0.02	0.02	2.0e-04	5.3e-04	2.3e-03	2.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
Bone: apparent density	0.3	0.4	1.1	-0.1	-0.5	-0.5	-0.6	-1.0	0.7
Area under the delay curve	1.6	1.6	3.4	-0.3	-0.1	-1.4	-1.8	-1.2	1.8
BMI with tail	0.6	1.9	3.2	0.9	-1.1	-1.7	-1.8	-0.8	1.6
BMI without tail	0.1	0.2	0.6	-0.1	-0.3	-0.4	-0.5	-0.8	0.6
Body weight	0.2	0.9	1.5	1.0	-0.8	-1.2	-1.2	-0.1	1.0
Weight adjusted by age	0.5	0.5	1.3	-1.2	1.1	0.6	0.3	-0.0	-0.2
Bone surface	1.7	3.1	5.9	2.4	-2.1	-2.0	-1.6	0.5	1.1
Bone volume	1.3	2.2	3.3	1.8	-1.8	-1.8	-1.5	-0.0	1.2
Breakpoint value in progressive ratio session	0.2	0.2	0.4	-0.2	0.7	0.3	0.1	0.6	-0.2
Number of licking bursts	0.5	0.5	2.0	-0.6	-0.1	-0.3	-0.4	-1.4	0.7
Context. condit. distance diff. score	0.3	0.3	1.1	-0.5	1.0	0.4	0.1	0.6	-0.4
Locomotion velocity, session 1	0.1	0.1	0.3	0.0	-0.0	0.3	0.5	0.2	-0.5
Locomotion distance, session 1	0.2	0.3	1.1	0.2	0.2	0.3	0.3	1.0	-0.6
Locomotion velocity, session 2	0.3	0.4	1.2	-0.0	0.4	0.5	0.6	1.1	-0.7
Locomotion distance, session 2	0.1	0.2	0.3	-0.6	0.3	-0.2	-0.4	-0.2	0.5
Locomotion velocity, session 3	1.8	2.1	5.9	1.8	-0.9	0.2	0.8	2.4	-1.3
Locomotion distance, session 3	0.4	0.5	1.2	0.6	-1.1	-0.8	-0.6	-0.3	0.5
Stereotopy head waving bouts, day 3	1.1	1.3	2.7	1.0	-1.1	0.9	1.6	0.7	-1.4
Stereotopy head waving duration, day 3	0.9	1.1	1.9	1.1	-1.0	0.7	1.4	0.8	-1.2
Locomotion velocity, session 7	0.8	0.9	2.3	-1.5	1.2	1.0	0.7	-0.5	-0.5
Locomotion distance, session 7	1.2	1.5	4.9	-2.2	1.2	0.3	-0.3	-1.4	0.5
Stereotopy head waving bouts, day 7	2.2	2.5	5.0	1.6	-0.4	1.0	1.7	2.2	-1.9
Stereotopy head waving duration, day 7	2.2	2.7	7.1	1.7	-0.1	0.9	1.4	2.7	-1.9
Locomotion velocity, session 8	1.2	1.5	4.1	1.6	-0.7	0.2	0.7	2.0	-1.1
Locomotion distance, session 8	0.2	0.3	0.9	-0.8	1.0	0.1	-0.2	0.5	-0.1
Degree of sensitization distance	1.4	1.4	3.9	-2.0	1.6	1.0	0.4	-0.6	-0.4
Degree of sensitization stereotypy	1.5	1.7	4.9	1.8	-0.4	0.1	0.6	2.2	-1.1
Conditioned locomotion	0.4	0.5	0.9	-1.0	1.0	0.8	0.6	0.0	-0.5
Cocaine response after cond. corrected	1.1	1.2	1.8	-0.5	1.2	1.2	1.1	1.1	-1.3
Cocaine response after cond. not corrected	1.3	1.5	2.2	-0.9	1.5	1.3	1.1	1.0	-1.3
Cocaine response before conditioning	0.1	0.1	0.2	-0.4	0.3	-0.1	-0.4	-0.2	0.3
Saline control response	0.3	0.3	1.2	0.6	-0.1	0.2	0.3	1.1	-0.6
Bone: connectivity density	0.6	0.9	1.2	0.8	-1.1	-1.1	-1.0	-0.5	0.9
Bone: cortical apparent density	0.1	0.2	0.3	0.1	-0.3	-0.5	-0.5	-0.4	0.5
Bone: cortical area	0.3	0.5	1.6	0.2	0.6	0.5	0.5	1.3	-0.7
Bone: cortical porosity	0.1	0.1	0.4	-0.6	0.5	0.3	0.2	-0.3	-0.0
Bone: cortical porosity	0.2	0.2	0.5	-0.7	0.5	0.1	-0.1	-0.4	0.2
Bone: cortical thickness	2.0	3.3	5.4	-1.7	2.3	2.1	1.8	1.0	-1.6
Bone: cortical thickness	0.2	0.2	0.5	-0.7	0.7	0.3	0.1	-0.2	0.0
Bone: cortical tissue density	0.2	0.2	0.3	0.2	-0.4	-0.6	-0.6	-0.4	0.6
Condit. Reinf. active minus inactive responses	0.0	0.0	0.0	-0.0	0.1	0.1	0.1	0.0	-0.1
Condit. Reinf. active-inactive response ratio	0.4	0.4	0.7	-0.5	0.7	0.8	0.8	0.5	-0.7
Condit. Reinf. active responses	0.0	0.0	0.0	0.2	0.1	-0.1	-0.2	0.0	0.1
Condit. Reinf. inactive responses	0.0	0.0	0.1	0.3	-0.2	-0.1	-0.0	0.1	-0.1
Incentive salience index mean	0.0	0.0	0.1	-0.3	0.3	0.1	-0.0	-0.1	0.1
Condit. Reinf. lever presses	0.2	0.3	0.8	-0.7	0.9	0.5	0.2	0.2	-0.2
Condit. Reinf. active minus inactive responses	0.2	0.3	0.8	0.4	0.2	-0.5	-0.6	0.9	0.2
Condit. Reinf. active-inactive response ratio	0.8	0.9	2.0	-0.0	-0.1	-1.1	-1.4	-0.6	1.2
Condit. Reinf. active responses	0.6	0.8	3.2	0.8	0.1	0.3	0.5	1.8	-0.9
Condit. Reinf. inactive responses	1.4	1.7	3.9	0.7	0.1	1.0	1.4	2.0	-1.7
Condit. Reinf. lever presses	0.2	0.3	1.0	0.8	-0.1	-0.0	0.1	1.0	-0.4
Condit. Reinf. lever reinforcers received	0.5	0.7	3.0	0.9	-0.0	0.1	0.3	1.7	-0.7
Conditioned reinforcement - actives	0.3	0.3	0.6	-0.6	0.8	-0.2	-0.6	-0.1	0.6
Conditioned reinforcement - inactives	2.3	2.5	4.3	-1.8	2.1	1.9	1.5	0.5	-1.2
Conditioned locomotion	0.1	0.2	0.4	-0.6	0.4	0.5	0.4	-0.2	-0.0
Patch foraging indifference point 0 sec	3.4	5.4	7.6	-1.6	2.4	2.7	2.6	1.9	-2.5
Patch foraging indifference point AUC	0.8	1.0	3.3	1.1	-0.1	0.3	0.6	1.8	-0.9
Delay disc. indifference point, 0s delay	1.3	1.4	2.9	0.3	-0.4	-1.4	-1.7	-0.9	1.6
Delay disc. indifference point, 16s delay	0.9	0.9	1.5	-0.0	-0.6	-0.9	-1.0	-1.2	1.2
Delay disc. indifference point, 2s delay	1.5	1.7	3.3	0.3	-0.7	-1.6	-1.8	-1.0	1.7
Delay disc. indifference point, 24s delay	0.6	0.5	1.1	-1.0	0.7	-0.2	-0.7	-0.9	0.7
Delay disc. indifference point, 4s delay	1.4	1.4	3.0	0.0	-0.3	-1.4	-1.7	-0.8	1.7
Delay disc. indifference point, 8s delay	0.5	0.6	0.9	-0.8	0.5	-0.5	-0.9	-0.8	0.9
Indifference point function ln k	0.4	0.6	1.6	-1.3	1.1	0.7	0.3	-0.5	-0.2
Indifference point function log k	0.4	0.6	1.6	-1.3	1.1	0.7	0.3	-0.5	-0.2
Patch foraging total patch changes 0 sec	2.9	4.6	6.3	-1.2	2.2	2.5	2.4	1.9	-2.4
Patch foraging total patch changes 12 sec	1.6	2.0	5.2	0.9	0.3	1.0	1.5	2.3	-1.7
Patch foraging total patch changes 18 sec	1.6	2.1	5.6	0.4	0.8	1.2	1.4	2.4	-1.7
Patch foraging total patch changes 24 sec	0.5	0.7	2.8	0.6	0.5	0.2	0.3	1.7	-0.7
Patch foraging total patch changes 6 sec	3.0	4.4	7.5	0.2	1.0	2.1	2.5	2.7	-2.7
Patch foraging time to switch 0 sec	0.7	1.1	2.0	-0.1	-0.9	-1.0	-1.1	-1.4	1.2
Patch foraging water rate 0 sec	1.0	1.6	4.0	1.5	-0.3	0.5	1.0	2.0	-1.3
Patch foraging water rate 12 sec	1.7	2.6	4.7	-1.8	2.2	1.9	1.5	0.6	-1.4
Patch foraging water rate 18 sec	0.4	0.5	0.9	0.9	-0.8	-0.9	-0.8	-0.0	0.6
Patch foraging water rate 24 sec	0.3	0.4	1.4	-0.7	1.2	0.2	-0.2	0.5	-0.1
Patch foraging water rate 6 sec	0.1	0.2	0.5	-0.3	0.7	0.3	0.2	0.6	-0.2
Seeking ratio, delayed vs. immediate footshock	1.0	1.2	3.8	-0.1	-0.7	-0.8	-0.9	-2.0	1.1
Distance traveled before self-admin	0.1	0.1	0.2	0.2	0.1	-0.2	-0.2	0.4	0.2
Distance traveled after self-admin	1.5	1.7	2.5	0.4	-1.1	-1.4	-1.4	-1.5	1.6
Extensor digitorum longus weight	2.3	9.0	22.5	4.7	-4.1	-2.9	-1.8	0.7	1.4
Bone: elastic displacement	0.1	0.2	0.4	-0.6	0.2	0.3	0.2	-0.6	-0.0
Bone: elastic work	0.1	0.2	0.4	0.1	0.1	0.5	0.6	0.3	-0.5
Bone: endosteal estimation	2.9	6.2	9.0	2.8	-3.0	-3.0	-2.6	-0.5	2.1
Bone: endosteal perimeter	0.7	1.4	2.8	1.7	-1.2	-1.3	-1.1	0.8	0.6
Epididymis fat weight	2.8	6.4	11.7	3.4	-2.6	-3.0	-2.6	0.7	1.9
Delta time in closed arm before/after self-admin	1.2	1.2	2.3	0.0	-0.7	-1.1	-1.3	-1.5	1.2
Delta time in open arm before/after self-admin	0.2	0.2	0.6	0.8	-0.6	-0.4	-0.3	0.1	0.2
Diff in mean of infusions in LGA sessions	1.7	1.9	5.2	0.5	0.7	1.1	1.3	2.3	-1.6
Delay discount exponential model param	1.3	1.4	2.9	0.4	-0.0	1.3	1.7	1.1	-1.6
Extinction: sum of active levers before priming	0.9	0.9	3.1	0.3	0.6	0.6	0.7	1.7	-0.9
Active lever presses in extinction session 6	3.8	3.7	6.9	-0.5	1.0	2.3	2.6	1.7	-2.4
Bone: final force	0.2	0.3	0.8	0.9	-0.3	-0.2	0.0	0.9	-0.2
Bone: final moment	0.2	0.3	1.0	0.8	-0.3	-0.1	0.1	1.0	-0.3
Food consumed during 24 hour testing period	0.8	1.0	1.4	-1.0	1.1	1.2	1.0	0.6	-1.0
Glucose	1.5	2.3	6.7	2.6	-1.7	-0.7	-0.0	1.9	-0.4
Heart weight	2.9	4.1	5.3	1.4	-2.1	-2.2	-2.0	-2.1	2.3
Delay discount hyperbolic model param	1.6	1.6	3.4	0.2	0.2	1.4	1.8	1.1	-1.8
Intermittent access intake day 1-15 change	1.5	1.5	2.1	-1.0	1.2	1.5	1.4	0.8	-1.3
Intermittent access intake escalation	1.6	1.6	2.3	-0.9	1.2	1.5	1.5	1.0	-1.3
Intermittent access intake escalation 2	3.0	2.9	3.9	-0.8	1.3	1.9	2.0	2.0	-1.9
Intermitt. access day 1 inactive lever presses	2.4	2.6	4.5	-2.1	1.9	1.9	1.6	0.2	-1.3
Intermitt. access day 15 inactive lever presses	1.3	1.4	2.5	-1.0	1.6	1.3	1.1	1.1	-1.0
Intermitt. access escalation Index	0.1	0.1	0.2	-0.1	0.4	0.4	0.3	0.1	-0.4
Intermittent access day 1 total infusions	0.6	0.6	1.9	-1.0	1.4	0.7	0.3	0.6	-0.1
Intermittent access day 15 total infusions	4.2	4.7	6.7	-2.0	2.4	2.6	2.4	1.5	-1.9
Intermittent access terminal intake (last 3 days)	3.2	3.5	5.0	-1.9	2.2	2.2	1.9	1.4	-1.5
Intermittent access total infusions	2.4	2.6	4.3	-1.7	2.1	1.9	1.6	1.1	-1.2
Intermittent access day 1 locomotion	1.2	1.2	3.3	-1.8	1.8	0.9	0.4	-0.1	-0.0
Intermittent access day 15 total locomotion	2.5	2.7	3.5	-1.1	1.8	1.9	1.7	1.7	-1.5
Intermittent access total locomotion	3.8	4.4	7.6	-2.0	2.8	2.4	2.0	1.6	-1.7
Intermittent access standard deviation	1.9	2.0	3.7	-0.9	1.0	1.8	1.9	1.1	-1.5
Left kidney weight	0.8	2.2	4.4	-2.1	1.5	-0.4	-1.3	-1.6	1.4
Right kidney weight	0.8	2.2	6.8	-2.6	2.0	0.3	-0.6	-1.2	0.7
Cocaine induced anxiety	0.4	0.4	0.6	-0.2	0.6	0.7	0.7	0.8	-0.6
Post-drug Anxiety	0.7	0.7	2.3	0.3	0.5	0.6	0.7	1.5	-0.9
Baseline Anxiety	0.1	0.1	0.2	-0.0	-0.0	0.1	0.1	0.3	-0.5
Tail length	0.7	2.0	2.9	-1.3	1.7	1.7	1.5	0.8	-1.3
Length with tail	0.1	0.3	0.5	-0.3	0.6	0.5	0.5	0.7	-0.4
Length without tail	0.0	0.1	0.3	0.3	0.0	-0.1	-0.2	0.6	0.0
Times rat made contact with spout	5.6	6.5	11.8	-3.4	3.1	2.9	2.3	-0.2	-1.9
Lifetime Intake	0.7	0.8	1.4	-1.0	1.2	1.0	0.7	0.6	-0.5
Liver weight, left	0.1	0.2	0.8	-0.4	0.9	0.3	0.1	0.4	-0.2
Liver weight, right	0.1	0.2	0.5	-0.6	0.0	-0.2	-0.4	-0.7	0.4
Locomotor activity	1.5	2.4	7.5	-2.7	2.3	1.3	0.5	-0.4	-0.2
Locomotor testing distance	1.3	2.2	3.7	-1.9	1.9	1.7	1.3	0.4	-1.0
Locomotor testing rearing	0.3	0.5	1.5	-1.2	1.0	0.3	-0.2	-0.3	0.2
Locomotion in novel chamber	0.5	0.6	0.8	-0.5	0.8	0.9	0.8	0.5	-0.9
Locomotion in novel chamber post-restriction	1.4	1.7	3.2	1.6	-1.8	-1.3	-0.9	-0.8	1.0
Fecal boli incidents, locomotor time 1	0.7	0.8	1.6	-0.6	0.6	-0.8	-1.3	-0.5	1.2
Change in fecal boli incidents, locomotor task	1.0	1.0	2.6	-1.6	1.2	0.9	0.6	-0.6	-0.3
Time >=10cm from walls, locomotor time 1	1.1	1.1	1.6	-0.6	1.0	1.2	1.3	0.8	-1.2
Bouts of movement, locomotor time 1	0.1	0.1	0.3	0.3	-0.0	0.2	0.4	0.6	-0.5
Total resting periods, locomotor time 1	0.1	0.1	0.4	0.1	0.2	0.3	0.4	0.6	-0.5
Rest time, locomotor task time 1	1.5	1.7	3.6	0.3	-0.6	-1.6	-1.9	-0.8	1.6
Distance moved, locomotor task time 1	0.4	0.5	1.2	-0.2	-0.2	0.8	1.1	-0.5	-0.8
Vertical activity count, locomotor time 1	0.8	0.8	2.0	0.3	0.0	1.1	1.4	0.5	-1.2
Time >=10cm from walls, locomotor time 2	0.5	0.5	1.4	0.9	-1.2	-0.7	-0.4	-0.2	0.4
Bouts of movement, locomotor time 2	0.8	0.9	2.0	1.4	-0.3	-0.8	-0.7	1.3	0.4
Total resting periods, locomotor time 2	0.4	0.4	1.4	0.7	0.3	-0.3	-0.4	1.2	0.2
Rest time, locomotor task time 2	0.7	0.8	2.0	-1.0	1.4	0.8	0.5	0.7	-0.7
Distance moved, locomotor task time 2	1.2	1.4	3.5	1.0	-1.9	-1.0	-0.6	-1.2	0.9
Vertical activity count, locomotor time 2	1.2	1.3	2.6	1.3	-1.6	-1.1	-0.7	-0.7	1.0
Light reinforcement 1	0.4	0.6	1.4	0.0	-0.3	-1.0	-1.2	-0.5	1.0
Light reinforcement 2	2.2	2.9	5.7	2.4	-1.8	-2.0	-1.6	1.0	1.0
Bone: marrow area	2.8	6.2	8.9	2.8	-2.9	-3.0	-2.6	-0.4	2.1
Bone: maximum diameter	0.4	0.7	1.9	1.3	-0.4	-0.5	-0.3	1.4	-0.2
Bone: maximum force	0.2	0.3	1.0	1.0	-0.7	-0.2	0.1	0.6	-0.2
Bone: maximum moment	0.2	0.3	0.8	0.9	-0.5	-0.2	0.0	0.6	-0.2
Mean time between licks in bursts	1.0	1.5	4.2	-2.1	1.1	1.1	0.7	-1.2	-0.3
Mean num. licks in bursts	2.5	3.0	4.1	-1.1	1.7	2.0	2.0	1.5	-2.0
Cd content in liver	1.1	1.2	1.9	-1.2	0.8	1.4	1.4	-0.5	-1.0
Co content in liver	0.1	0.2	0.3	0.2	-0.2	-0.5	-0.5	-0.3	0.5
Cu content in liver	0.1	0.1	0.1	0.2	-0.2	0.2	0.3	0.2	-0.3
Fe content in liver	1.2	1.4	2.9	0.8	-0.4	1.1	1.7	1.2	-1.5
K content in liver	1.0	1.0	1.7	1.0	-1.3	-1.1	-0.9	-0.7	0.9
Mg content in liver	0.7	0.7	1.7	1.2	-1.3	-0.7	-0.3	-0.3	0.4
Mn content in liver	1.2	1.4	2.3	1.1	-1.0	-1.5	-1.5	-0.3	1.2
Na content in liver	1.4	1.5	3.9	2.0	-1.2	-0.5	0.1	1.8	-0.4
Rb content in liver	0.2	0.2	0.9	-0.5	0.3	0.0	-0.1	-0.9	0.3
Se content in liver	1.0	1.2	2.9	-0.4	0.2	1.4	1.7	0.4	-1.4
Sr content in liver	0.9	0.9	2.5	-1.6	1.3	0.7	0.3	-0.6	-0.1
Zn content in liver	1.1	1.2	1.7	-0.6	1.0	1.3	1.3	0.9	-1.3
Bone: minimum diameter	1.6	3.0	8.0	2.8	-2.2	-1.6	-1.0	1.2	0.5
Time in familiar zone, hab. session 1	0.1	0.1	0.2	-0.3	0.4	-0.2	-0.4	0.2	0.1
Time in novel zone, hab. session 1	1.0	0.9	2.7	1.0	-1.6	-0.8	-0.4	-0.8	0.7
Total zone transitions, hab. session 1	1.0	1.4	4.2	-2.0	1.8	0.9	0.4	-0.1	-0.2
Total locomotion distance, hab. session 1	0.8	1.1	3.6	-1.9	1.5	0.9	0.4	-0.3	-0.2
Locomotion velocity, hab. session 1	0.9	1.2	4.0	-2.0	1.5	0.9	0.4	-0.4	-0.2
Time in familiar zone, hab. session 2	0.8	0.8	2.0	0.6	-0.4	-1.2	-1.4	-0.2	1.0
Time in novel zone, hab. session 2	0.2	0.2	0.6	-0.3	-0.1	0.6	0.8	-0.2	-0.4
Total zone transitions, hab. session 2	0.7	0.9	2.7	-1.6	1.2	-0.0	-0.7	-0.6	0.6
Total locomotion distance, hab. session 2	1.3	1.7	5.1	-2.3	1.4	0.1	-0.7	-1.3	0.8
Locomotion velocity, hab. session 2	1.2	1.7	5.3	-2.3	1.5	0.1	-0.6	-1.2	0.7
Novel to familiar place preference ratio	0.4	0.4	1.4	-0.1	-0.7	-0.3	-0.2	-1.2	0.4
Novelty place preference	0.8	0.8	1.9	0.3	-1.2	-0.8	-0.6	-1.4	0.8
Time in novel zone, NPP test	1.0	1.0	1.7	0.5	-1.3	-0.9	-0.8	-1.3	0.9
Total zone transitions, NPP test	0.2	0.3	0.8	-0.7	0.9	0.3	-0.0	0.6	-0.2
Total locomotion distance, NPP test	0.2	0.3	0.7	-0.8	0.4	-0.1	-0.3	-0.7	0.4
Locomotion velocity, NPP test	0.3	0.4	1.1	-1.1	0.6	0.1	-0.2	-0.7	0.3
Intraocular pressure	0.6	0.8	1.3	0.8	-1.1	-0.8	-0.6	-1.1	0.9
Delta distance traveled before/after self-admin	1.7	1.9	4.0	-0.3	-0.7	-1.3	-1.5	-2.0	1.7
Delta ambulatory time before/after self-admin	1.7	1.9	4.0	-0.4	-0.5	-1.2	-1.6	-2.0	1.7
Parametrial fat weight	1.8	3.5	5.7	1.7	-1.9	-2.4	-2.3	-0.8	1.7
Pavlov. Cond. lever latency	0.1	0.2	0.4	-0.2	-0.1	-0.3	-0.4	-0.7	0.5
Pavlov. Cond. magazine entry latency	0.2	0.3	0.7	-0.9	0.4	0.2	0.0	-0.8	0.1
Pavlov. Cond. change in total contacts	0.0	0.0	0.1	-0.2	0.4	0.0	-0.1	0.1	-0.0
Pavlov. Cond. index score	0.1	0.1	0.1	-0.3	0.3	0.3	0.3	-0.0	-0.3
Pavlov. Cond. latency score	0.1	0.1	0.2	-0.5	0.4	0.3	0.2	-0.1	-0.2
Pavlov. Cond. lever contacts	0.6	0.7	1.0	-0.3	0.9	0.9	0.8	1.0	-1.0
Pavlov. Cond. magazine entry number	0.1	0.1	0.3	0.3	0.0	-0.0	-0.0	0.6	-0.1
Pavlov. Cond. intertrial magazine entries	2.6	3.1	7.4	2.7	-1.3	0.3	1.2	2.5	-1.4
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.1	0.1	-0.3	0.3	0.3	0.2	-0.0	-0.2
Pavlov. Cond. response bias	0.2	0.3	0.4	-0.5	0.7	0.6	0.5	0.2	-0.5
Pavlov. Cond. lever latency	0.5	0.7	2.4	-1.3	0.3	0.4	0.2	-1.5	0.3
Pavlov. Cond. magazine entry latency	0.4	0.4	1.1	-0.2	0.8	0.5	0.3	1.0	-0.6
Pavlov. Cond. change in total contacts	0.4	0.5	1.0	1.0	-0.4	-0.8	-0.8	0.7	0.4
Pavlov. Cond. index score	0.6	0.8	2.8	0.4	0.6	0.6	0.6	1.7	-0.9
Pavlov. Cond. latency score	0.4	0.5	1.6	0.1	0.8	0.5	0.4	1.2	-0.7
Pavlov. Cond. lever contacts	0.3	0.4	1.1	0.9	-0.2	-0.4	-0.4	1.0	-0.0
Pavlov. Cond. magazine entry number	0.1	0.1	0.2	-0.4	-0.0	0.4	0.5	-0.4	-0.3
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.5	0.4	-0.2	0.3	0.5	0.7	-0.6
Pavlov. Cond. lever-magazine prob. diff.	0.6	0.8	2.6	0.3	0.7	0.6	0.6	1.6	-0.9
Pavlov. Cond. response bias	0.3	0.4	1.4	0.8	0.0	-0.2	-0.2	1.2	-0.2
Time in closed arm before self-admin	0.4	0.5	0.8	0.7	-0.5	-0.9	-0.9	0.1	0.8
Time in closed arm after self-admin	6.0	6.2	9.9	0.5	-1.6	-2.8	-3.1	-2.6	3.1
Time in open arm before self-admin	0.1	0.1	0.2	-0.4	0.3	0.2	0.1	-0.1	-0.1
Time in open arm after self-admin	1.1	1.2	2.6	0.4	0.4	1.0	1.2	1.6	-1.4
Bone: periosteal estimation	0.8	1.6	3.4	1.8	-1.5	-1.4	-1.1	0.5	0.7
Bone: periosteal perimeter	0.3	0.4	1.7	0.8	-0.1	-0.1	-0.0	1.3	-0.4
Bone: post-yield work	0.6	0.8	1.8	1.2	-0.5	0.2	0.6	1.3	-0.8
Progressive ratio test 1 active lever presses	0.3	0.3	0.6	-0.8	0.7	-0.0	-0.3	-0.3	0.7
Progressive ratio test 1 breakpoint	0.4	0.4	0.9	-1.0	0.7	-0.0	-0.4	-0.5	0.7
Progressive ratio test 1 inactive lever presses	0.8	0.8	1.3	-1.1	1.1	1.1	1.0	0.2	-0.7
Progressive ratio test 2 active lever presses	2.2	2.4	3.5	-1.4	1.7	1.9	1.7	1.2	-1.3
Progressive ratio test 2 breakpoint	2.3	2.5	3.8	-1.3	1.7	2.0	1.8	1.2	-1.5
Progressive ratio test 2 inactive lever presses	4.7	5.4	7.6	-1.6	2.7	2.7	2.4	2.2	-2.2
Incentive Sensitization - Responses	2.0	2.0	3.1	-0.2	1.0	1.5	1.7	1.8	-1.6
Incentive Sensitization - Breakpoint	2.3	2.4	3.5	-0.3	1.1	1.7	1.8	1.9	-1.8
Sum of active levers in priming session hrs 5-6	1.5	1.5	2.6	0.1	0.5	1.3	1.6	1.5	-1.5
Progressive ratio	0.1	0.1	0.2	0.3	0.0	0.2	0.3	0.4	-0.4
Food seeking constrained by brief footshock	0.8	1.0	2.3	-1.5	1.1	1.1	0.8	-0.5	-0.7
Seeking ratio, punishment vs. effort	0.4	0.5	1.6	-1.3	0.5	0.4	0.2	-1.0	0.1
Retroperitoneal fat weight	1.1	3.5	7.4	2.7	-2.4	-2.1	-1.5	0.3	1.1
Reaction time number correct	0.2	0.2	0.7	0.1	0.4	0.4	0.4	0.8	-0.4
Reaction time mean minus median	0.8	1.0	1.4	-0.7	1.0	1.2	1.2	0.8	-1.1
Reaction time mean minus median AUC	1.1	1.5	2.4	-0.0	0.9	1.2	1.4	1.5	-1.5
Reaction time num false alarms	1.1	1.5	4.3	-2.1	1.3	1.2	0.8	-0.9	-0.5
Reaction time num false alarms AUC	1.1	1.6	5.2	-2.3	1.3	0.9	0.4	-1.2	-0.1
Reaction time trials correct on left	0.2	0.2	0.7	0.1	0.4	0.4	0.4	0.8	-0.4
Reaction time trials on left	0.2	0.3	0.7	0.1	0.4	0.4	0.5	0.9	-0.4
Reaction time mean	0.2	0.3	0.8	0.5	-0.9	-0.4	-0.1	-0.7	0.3
Reaction time mean AUC	0.1	0.1	0.2	0.3	-0.5	0.1	0.4	-0.2	-0.3
Median of all reaction times	1.0	1.3	2.4	0.8	-1.6	-1.1	-0.8	-1.3	1.0
Reaction time omissions	0.0	0.0	0.1	0.1	-0.3	-0.2	-0.2	-0.2	0.0
Reaction time false alarm rate	0.9	1.3	4.2	-2.0	1.0	0.7	0.3	-1.4	0.1
Reaction time premature initiation rate	1.0	1.3	2.0	1.2	-1.0	-1.4	-1.3	-0.4	1.2
Reaction time premature initiations	0.3	0.5	1.2	1.1	-0.5	-0.8	-0.6	0.3	0.5
Std. dev. reaction times	0.5	0.7	1.1	-0.8	0.7	1.0	1.0	0.2	-0.9
Reaction time trials completed	0.2	0.3	0.7	0.1	0.4	0.4	0.5	0.9	-0.4
Reaction time trials AUC	0.2	0.2	0.8	0.4	0.2	0.3	0.4	0.9	-0.4
Run reversals in cocaine runway, females	0.2	0.2	0.5	-0.7	0.7	0.2	-0.1	0.0	0.1
Run reversals in cocaine runway, males	0.8	0.8	1.8	-0.2	0.9	0.8	0.7	1.3	-0.9
Latency to leave start box in cocaine runway	0.4	0.5	1.0	0.1	-0.5	-0.7	-0.7	-1.0	0.8
Latency to leave start box in cocaine runway, F	0.9	1.0	3.1	-0.4	-0.6	-0.8	-0.9	-1.8	1.0
Latency to leave start box in cocaine runway, M	0.1	0.1	0.5	0.7	-0.2	-0.3	-0.2	0.4	0.1
Std. dev. time between licks in bursts	1.5	1.8	2.5	-0.9	1.4	1.6	1.5	1.0	-1.5
Total sessions with >9 infusions	0.5	0.5	1.5	-0.9	0.1	-0.2	-0.5	-1.2	0.8
Short access day 1 total inactive lever presses	1.9	2.1	3.1	-1.7	1.5	1.8	1.6	0.3	-1.3
Short access day 10 total inactive lever presses	0.3	0.4	0.8	0.3	-0.5	0.5	0.9	0.6	-0.7
Short access day 1 total infusions	0.1	0.1	0.3	-0.1	-0.3	-0.1	-0.2	-0.6	0.4
Short access day 10 total infusions	0.5	0.6	1.1	0.1	-0.6	-0.7	-0.7	-1.0	1.1
Short access total infusions	0.4	0.5	1.1	-0.1	-0.3	-0.7	-0.9	-0.8	1.0
Short access day 1 locomotion	0.5	0.5	1.7	-1.0	0.1	0.1	-0.1	-1.3	0.6
Short access day 10 total locomotion	0.1	0.1	0.3	-0.3	0.2	-0.3	-0.5	-0.3	0.6
Short access total locomotion	0.4	0.5	0.9	-0.3	-0.2	-0.6	-0.8	-0.8	1.0
One hour access (0.3 mA shock)	1.5	1.8	2.8	-1.2	1.7	1.4	1.1	1.4	-1.1
Compulsive drug intake	0.7	0.7	1.3	1.0	-0.4	-1.1	-1.1	0.6	0.5
One hour access (shock baseline)	3.0	3.5	5.2	-1.4	1.8	2.3	2.2	1.4	-1.9
Social response proportion	0.2	0.3	0.7	-0.8	0.8	0.4	0.1	-0.2	-0.0
Social responses	0.3	0.4	1.0	-1.0	0.9	0.1	-0.3	-0.4	0.4
Social time	0.1	0.1	0.1	0.3	0.1	-0.2	-0.3	0.4	0.1
Soleus weight	0.4	1.1	2.7	1.7	-1.0	-1.2	-0.9	0.7	0.5
Bone: stiffness	0.0	0.1	0.1	0.0	0.2	0.3	0.3	0.3	-0.3
Tibialis anterior weight	4.2	14.2	34.2	5.8	-5.2	-3.7	-2.4	0.7	1.9
Time to tail flick, vehicle, before self-admin	1.8	1.8	3.4	-1.8	1.1	1.6	1.5	-0.8	-0.8
Time to tail flick, vehicle, after self-admin	1.6	1.7	2.7	1.6	-1.4	-1.6	-1.4	0.1	0.9
Time to tail flick, test, before self-admin	0.8	0.8	2.1	-0.9	0.1	-0.5	-0.8	-1.4	1.0
Time to tail flick, test, after self-admin	1.2	1.2	2.2	-0.7	0.2	-0.9	-1.4	-1.5	1.3
Delta time to tail flick, vehicle, before/after SA	2.5	2.5	4.9	2.2	-1.4	-1.9	-1.7	0.8	0.9
Delta time to tail flick, test, before/after SA	0.0	0.0	0.0	0.1	0.1	-0.1	-0.2	-0.1	0.2
Tibia length	0.0	0.0	0.1	-0.0	-0.1	-0.2	-0.3	-0.0	0.3
Ambulatory time before self-admin	0.2	0.3	0.8	0.8	-0.3	-0.2	-0.0	0.9	-0.1
Ambulatory time after self-admin	0.9	1.0	1.5	0.6	-1.0	-1.1	-1.1	-0.9	1.2
Bone: tissue strength	0.2	0.2	0.5	-0.7	0.5	0.4	0.3	-0.3	-0.2
Total heroin consumption	2.1	2.4	6.0	-1.7	2.4	1.5	1.0	1.1	-1.0
Bone: trabecular number	0.3	0.4	0.8	-0.1	-0.4	-0.6	-0.7	-0.9	0.8
Bone: trabecular spacing	0.8	1.0	2.9	-1.7	1.6	0.7	0.2	-0.5	-0.1
Bone: trabecular thickness	0.4	0.4	1.0	1.0	-1.0	-0.6	-0.3	0.1	0.3
Bone: trabecular tissue density	0.5	0.7	2.3	-1.5	1.1	0.3	-0.2	-0.8	0.3
Water consumed over 24 hours	0.5	0.6	1.4	-0.9	1.2	0.8	0.5	0.3	-0.6
Number of responses in last shaping day	0.6	0.6	1.8	-0.8	0.1	-0.4	-0.6	-1.3	0.8