Hub : Genes

Nfia

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC mRNA stability Nfia 0.24 0.12 2.0e-11 0.2 0.23 0.2 0.23 7.8e-09 5.4e-10 5.5e-09 4.8e-10
2 NAcc mRNA stability Nfia 0.36 0.12 0.0e+00 0.26 0.26 0.25 0.26 1.6e-39 6.8e-40 8.2e-38 3.9e-39
3 Liver mRNA stability Nfia 0.03 0.03 1.5e-03 0.01 0.01 0 0.01 6.8e-02 1.2e-02 8.3e-02 4.8e-02
4 PL alternative TSS XM_039109300.2 0.02 0.02 5.5e-03 0.01 0.02 0.01 0.01 1.2e-02 6.3e-03 2.1e-02 1.6e-02
5 Adipose alternative TSS XM_063287185.1 0.07 0.05 2.2e-07 0.03 0.04 0.02 0.03 1.5e-04 2.6e-05 6.6e-03 1.8e-04
6 BLA alternative TSS XM_039109300.2 0.04 0.04 7.8e-03 0 0.02 0.01 0 1.7e-01 1.8e-02 1.1e-01 1.6e-01
7 Brain alternative polyA XM_063287182.1 0.03 0.02 4.2e-03 0 0.01 0 0 1.3e-01 1.5e-02 2.6e-01 1.4e-01
8 Brain alternative polyA NM_012988.2 0.03 0.02 5.1e-03 0.01 0.01 0 0 7.5e-02 2.0e-02 2.9e-01 1.4e-01
9 BLA alternative polyA NM_012988.2 0.05 0.04 6.2e-03 0.02 0.03 0.01 0.02 2.3e-02 1.8e-02 9.0e-02 3.8e-02
10 OFC mRNA stability Nfia 0.32 0.18 2.4e-06 0.2 0.23 0.2 0.22 1.6e-05 3.3e-06 1.3e-05 6.3e-06
11 pVTA mRNA stability Nfia 0.4 0.14 0.0e+00 0.43 0.43 0.44 0.44 1.3e-37 3.2e-37 2.8e-38 4.4e-38
12 PL mRNA stability Nfia 0.41 0.15 0.0e+00 0.38 0.39 0.39 0.39 1.1e-43 2.3e-45 3.0e-45 1.1e-45
13 BLA mRNA stability Nfia 0.37 0.17 0.0e+00 0.4 0.39 0.4 0.39 2.6e-22 8.8e-22 1.2e-22 3.7e-22
14 pVTA alternative polyA XM_063287182.1 0.04 0.04 6.8e-03 0.02 0.02 0.03 0.02 4.8e-03 1.0e-02 3.7e-03 6.3e-03
15 pVTA alternative polyA NM_012988.2 0.04 0.04 5.8e-03 0.02 0.02 0.03 0.02 4.3e-03 8.9e-03 3.5e-03 6.6e-03
16 Brain isoform ratio NM_012988.2 0.03 0.02 2.2e-03 0.02 0.02 0.01 0.01 1.0e-02 1.0e-02 2.6e-02 2.8e-02
17 LHb mRNA stability Nfia 0.3 0.22 1.5e-04 0.16 0.16 0.15 0.16 9.8e-05 1.2e-04 1.8e-04 1.6e-04
18 Adipose gene expression Nfia 0.37 0.26 6.8e-08 0.05 0.04 0.04 0.05 2.4e-06 1.0e-05 3.6e-05 4.4e-06
19 PL alternative TSS XM_039109303.2 1.16 0 1.1e-03 0 0 NA NA 8.1e-02 2.3e-01 NA NA
20 NAcc alternative polyA NM_012988.2 0.03 0.02 3.0e-04 0.02 0.02 0.02 0.02 1.4e-04 6.8e-04 3.4e-04 3.4e-04
21 Brain mRNA stability Nfia 0.27 0.11 0.0e+00 0.27 0.27 0.27 0.27 1.5e-25 1.3e-25 4.8e-25 3.6e-25
22 NAcc alternative polyA XM_063287182.1 0.03 0.03 1.2e-04 0.02 0.02 0.02 0.02 3.6e-04 2.2e-04 1.7e-04 2.5e-04
23 IL mRNA stability Nfia 0.78 0.13 3.7e-09 0.27 0.3 0.27 0.27 3.6e-07 4.7e-08 4.1e-07 4.1e-07
24 Eye mRNA stability Nfia 0.55 0.18 8.1e-07 0.21 0.23 0.23 0.21 3.7e-04 1.9e-04 1.8e-04 3.4e-04
25 PL alternative TSS XM_063287181.1 0.02 0.02 8.2e-03 0.01 0.01 0.02 0.01 2.4e-02 1.0e-02 3.0e-03 3.8e-02
26 PL alternative TSS NM_012988.2 0.02 0.02 6.4e-03 0.01 0.02 0.02 0.01 1.1e-02 5.0e-03 3.6e-03 1.2e-02
27 PL alternative TSS XM_039109300.2 0.03 0.03 8.9e-04 0.02 0.03 0.03 0.02 1.6e-03 6.0e-04 1.5e-04 1.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density0.50.81.5-1.2-0.7-1.21.11.11.2-1.11.11.1-1.10.8-0.81.00.7-0.7-1.20.80.80.7-0.8-0.80.9-0.50.8-0.6-0.30.6
Area under the delay curve1.01.52.0-1.4-1.4-1.41.41.41.3-1.41.41.4-1.31.3-1.31.31.3-1.3-1.31.21.31.3-1.2-1.31.1-1.20.7-0.10.1-0.0
BMI with tail0.82.84.62.11.72.1-2.0-2.0-2.02.0-2.0-2.01.9-1.61.5-2.1-1.41.42.0-1.6-1.4-1.51.51.6-1.71.3-1.30.20.1-0.4
BMI without tail0.63.14.12.01.92.0-2.0-2.0-2.02.0-2.0-2.02.0-1.91.8-2.0-1.81.82.0-1.8-1.8-1.71.81.9-1.91.7-1.40.2-0.1-0.2
Body weight0.10.40.90.90.60.9-0.8-0.8-0.80.8-0.8-0.80.8-0.50.5-0.9-0.50.50.9-0.5-0.4-0.50.50.5-1.00.3-0.30.30.3-0.4
Weight adjusted by age0.41.11.70.81.01.0-1.1-1.1-1.11.1-1.1-1.11.1-1.21.2-1.1-1.21.20.6-1.3-1.1-1.01.11.2-1.31.3-1.2-0.2-0.70.3
Bone surface1.22.43.31.51.71.5-1.6-1.6-1.51.6-1.6-1.61.6-1.71.8-1.6-1.71.81.4-1.6-1.7-1.81.61.6-1.51.6-1.0-0.9-1.30.9
Bone volume0.30.50.80.50.80.6-0.6-0.6-0.60.6-0.6-0.60.6-0.80.8-0.7-0.90.90.5-0.7-0.8-0.90.70.8-0.50.9-0.5-0.6-0.80.7
Breakpoint value in progressive ratio session0.91.63.2-0.7-1.3-1.01.11.11.0-1.11.11.1-1.11.4-1.41.11.4-1.4-0.41.41.41.3-1.5-1.51.5-1.81.60.81.5-1.5
Number of licking bursts0.00.00.20.1-0.10.1-0.1-0.1-0.10.1-0.1-0.10.00.2-0.10.10.2-0.20.30.10.20.1-0.2-0.20.1-0.40.20.40.1-0.3
Context. condit. distance diff. score1.82.23.0-1.4-1.6-1.61.61.61.6-1.61.61.6-1.61.7-1.71.61.7-1.6-1.51.71.61.4-1.5-1.71.3-1.71.4-0.70.10.3
Locomotion velocity, session 10.10.10.8-0.3-0.1-0.20.10.10.1-0.10.10.1-0.10.00.00.2-0.00.0-0.5-0.2-0.00.00.00.20.10.4-0.7-0.6-0.90.6
Locomotion distance, session 11.01.31.7-1.2-1.1-1.21.21.21.2-1.21.21.2-1.21.1-1.11.31.1-1.1-1.11.01.11.3-1.1-1.11.1-1.00.91.21.0-0.9
Locomotion velocity, session 20.20.30.80.30.40.4-0.4-0.4-0.40.4-0.4-0.50.5-0.50.5-0.4-0.50.50.4-0.7-0.5-0.40.50.7-0.50.8-0.50.90.2-0.7
Locomotion distance, session 20.10.21.80.10.20.0-0.0-0.00.00.0-0.0-0.00.0-0.00.00.1-0.00.00.4-0.2-0.10.10.10.00.00.10.31.40.8-1.1
Locomotion velocity, session 30.10.11.2-0.3-0.1-0.30.20.30.3-0.30.30.3-0.30.3-0.20.40.2-0.2-0.50.00.10.2-0.2-0.20.0-0.20.3-1.1-0.70.8
Locomotion distance, session 30.10.10.40.30.20.3-0.2-0.2-0.20.2-0.2-0.20.2-0.10.1-0.3-0.10.10.6-0.1-0.1-0.20.20.1-0.20.00.50.30.1-0.2
Stereotopy head waving bouts, day 30.91.02.6-0.6-0.9-0.70.80.80.8-0.80.80.8-0.91.0-1.10.81.1-1.1-0.41.11.11.2-1.1-1.21.0-1.41.11.31.6-1.2
Stereotopy head waving duration, day 30.81.02.3-0.8-0.9-0.80.90.90.9-0.90.90.9-0.91.0-1.00.91.0-1.0-0.51.01.01.1-1.0-1.11.0-1.21.01.41.5-1.2
Locomotion velocity, session 70.70.81.8-0.7-0.8-0.90.90.90.9-0.90.90.9-0.91.0-1.01.01.0-1.0-0.50.90.80.8-0.9-1.00.8-1.01.40.70.6-0.3
Locomotion distance, session 70.10.20.5-0.4-0.4-0.50.50.50.5-0.50.50.5-0.50.5-0.40.60.4-0.4-0.40.40.40.3-0.4-0.40.3-0.40.70.1-0.0-0.0
Stereotopy head waving bouts, day 70.91.02.11.31.11.2-1.2-1.2-1.21.2-1.2-1.21.1-1.01.0-1.2-0.90.91.4-0.8-1.0-1.11.00.9-1.00.7-0.30.2-0.0-0.2
Stereotopy head waving duration, day 70.50.70.91.00.90.9-0.9-0.9-0.90.9-0.9-0.90.9-0.80.8-0.9-0.80.81.0-0.8-0.8-0.80.90.8-1.00.7-0.30.1-0.1-0.1
Locomotion velocity, session 80.40.50.9-0.7-0.6-0.80.80.80.8-0.80.80.8-0.80.7-0.70.90.7-0.7-0.60.80.60.6-0.6-0.70.6-0.61.00.30.1-0.1
Locomotion distance, session 80.81.21.6-1.2-1.2-1.31.21.21.2-1.21.21.2-1.21.2-1.21.21.2-1.2-1.21.21.11.0-1.1-1.11.0-1.00.8-0.20.1-0.0
Degree of sensitization distance0.10.10.10.20.30.2-0.3-0.2-0.20.2-0.2-0.20.2-0.20.3-0.0-0.30.3-0.0-0.3-0.3-0.20.20.2-0.40.1-0.1-0.3-0.20.2
Degree of sensitization stereotypy1.31.41.91.31.31.3-1.3-1.3-1.31.3-1.3-1.31.3-1.21.2-1.4-1.21.21.3-1.1-1.3-1.41.31.2-1.41.2-0.6-0.7-0.80.5
Conditioned locomotion0.30.42.60.5-0.10.5-0.3-0.3-0.40.3-0.3-0.30.30.1-0.2-0.50.2-0.21.20.10.20.0-0.2-0.00.4-0.3-0.41.61.4-1.6
Cocaine response after cond. corrected0.40.72.81.10.90.9-0.9-0.9-0.90.8-0.8-0.80.8-0.70.6-0.9-0.70.71.7-0.6-0.6-0.60.60.6-0.40.4-0.01.00.7-1.0
Cocaine response after cond. not corrected0.20.31.20.80.70.7-0.6-0.6-0.60.6-0.6-0.60.6-0.50.5-0.6-0.50.51.1-0.6-0.5-0.30.50.4-0.30.20.10.60.5-0.6
Cocaine response before conditioning0.10.11.0-0.3-0.1-0.30.20.30.3-0.30.30.3-0.30.2-0.20.50.2-0.2-1.00.00.10.5-0.1-0.3-0.1-0.20.2-0.6-0.40.7
Saline control response0.20.20.60.50.10.6-0.5-0.6-0.60.5-0.6-0.60.6-0.40.4-0.7-0.40.40.3-0.4-0.4-0.50.40.5-0.40.5-0.80.1-0.20.2
Bone: connectivity density1.01.62.31.11.51.1-1.2-1.2-1.11.2-1.2-1.21.2-1.51.5-1.2-1.51.51.0-1.4-1.4-1.51.41.4-1.31.5-0.7-0.9-1.10.9
Bone: cortical apparent density4.57.010.0-3.2-2.9-2.92.92.92.9-2.92.92.9-2.92.8-2.82.82.8-2.8-2.82.72.82.6-2.8-2.72.8-2.52.00.10.70.0
Bone: cortical area0.30.40.70.60.80.6-0.6-0.6-0.60.6-0.6-0.60.6-0.80.8-0.7-0.80.80.7-0.7-0.7-0.80.70.7-0.60.7-0.30.20.00.0
Bone: cortical porosity0.40.41.00.70.70.7-0.7-0.7-0.70.7-0.7-0.70.7-0.70.7-0.7-0.70.71.0-0.6-0.6-0.60.60.7-0.30.7-0.30.40.2-0.4
Bone: cortical porosity0.70.81.41.01.01.0-0.9-1.0-0.91.0-1.0-1.01.0-1.01.0-1.0-0.90.91.2-0.9-0.9-0.90.81.0-0.70.9-0.50.1-0.0-0.2
Bone: cortical thickness0.10.20.7-0.4-0.2-0.50.50.50.5-0.50.50.5-0.50.3-0.40.40.3-0.3-0.30.30.40.4-0.4-0.50.5-0.40.60.70.8-0.3
Bone: cortical thickness0.10.11.40.20.2-0.00.00.00.1-0.00.00.0-0.0-0.10.00.1-0.10.00.7-0.00.10.2-0.1-0.00.4-0.00.61.20.8-0.9
Bone: cortical tissue density4.36.89.7-3.1-2.9-2.92.92.92.9-2.92.92.9-2.92.8-2.82.72.8-2.8-2.82.72.72.5-2.8-2.72.7-2.41.90.00.60.1
Condit. Reinf. active minus inactive responses0.10.10.9-0.1-0.1-0.20.10.20.2-0.20.20.2-0.20.2-0.20.20.1-0.1-0.4-0.00.20.1-0.2-0.20.1-0.20.2-0.9-0.50.6
Condit. Reinf. active-inactive response ratio0.10.10.2-0.1-0.3-0.00.10.10.1-0.10.10.1-0.10.3-0.30.00.3-0.30.20.20.40.2-0.4-0.30.4-0.40.3-0.10.3-0.3
Condit. Reinf. active responses0.20.21.50.00.2-0.0-0.1-0.1-0.00.1-0.1-0.10.1-0.20.3-0.0-0.30.3-0.6-0.4-0.2-0.20.30.3-0.50.4-0.3-1.2-1.01.0
Condit. Reinf. inactive responses0.20.31.10.10.40.1-0.2-0.2-0.20.2-0.3-0.20.3-0.50.6-0.2-0.60.6-0.4-0.5-0.6-0.50.70.7-0.81.0-0.7-0.5-1.00.7
Incentive salience index mean0.00.00.40.1-0.0-0.00.00.00.0-0.00.00.0-0.00.0-0.0-0.00.0-0.0-0.2-0.10.1-0.0-0.0-0.1-0.0-0.10.2-0.6-0.30.4
Condit. Reinf. lever presses0.00.10.2-0.0-0.3-0.20.30.30.3-0.30.30.3-0.30.3-0.30.20.3-0.3-0.00.40.30.3-0.2-0.30.2-0.30.50.20.3-0.3
Condit. Reinf. active minus inactive responses0.60.92.2-1.2-0.8-1.21.21.21.2-1.21.21.1-1.10.9-0.91.20.8-0.9-1.50.70.91.0-0.9-0.91.0-0.60.6-0.30.00.3
Condit. Reinf. active-inactive response ratio0.10.20.6-0.6-0.2-0.60.50.50.5-0.50.50.5-0.50.3-0.30.50.2-0.3-0.80.10.20.4-0.3-0.20.50.0-0.1-0.6-0.30.4
Condit. Reinf. active responses0.91.32.8-1.3-1.0-1.41.31.31.3-1.31.31.3-1.31.1-1.11.41.1-1.1-1.70.81.21.2-1.2-1.11.2-0.90.9-0.30.10.5
Condit. Reinf. inactive responses1.82.74.1-1.8-1.7-1.81.81.81.8-1.81.81.8-1.81.8-1.71.91.7-1.7-2.01.51.81.7-1.8-1.71.6-1.71.5-0.00.50.3
Condit. Reinf. lever presses1.31.93.21.41.61.4-1.5-1.5-1.41.4-1.4-1.51.5-1.51.5-1.3-1.51.51.2-1.8-1.4-1.51.41.5-1.21.5-1.1-0.9-1.00.8
Condit. Reinf. lever reinforcers received0.50.82.1-1.1-0.6-1.11.01.01.0-1.01.01.0-1.00.8-0.81.20.7-0.7-1.40.40.80.8-0.8-0.80.9-0.50.7-0.5-0.20.7
Conditioned reinforcement - actives0.00.10.5-0.1-0.4-0.40.40.40.4-0.40.40.3-0.30.3-0.30.10.4-0.4-0.10.40.40.1-0.5-0.20.7-0.10.0-0.2-0.00.3
Conditioned reinforcement - inactives0.30.81.7-1.0-1.3-1.01.11.01.0-1.01.01.0-1.01.0-1.00.51.1-1.0-0.91.11.10.6-0.9-0.80.8-0.70.30.30.5-0.0
Conditioned locomotion0.20.41.7-0.1-0.8-0.20.40.30.3-0.30.30.3-0.30.5-0.60.00.7-0.70.10.60.70.4-0.7-0.40.9-0.50.11.31.1-1.2
Patch foraging indifference point 0 sec3.610.014.13.53.13.6-3.5-3.5-3.53.5-3.5-3.53.5-3.33.2-3.8-3.23.23.7-3.2-3.0-3.33.13.4-2.93.2-2.80.4-0.8-0.2
Patch foraging indifference point AUC0.30.82.00.90.80.8-0.8-0.8-0.80.8-0.8-0.90.9-0.91.0-0.7-0.90.90.3-1.0-0.9-0.91.01.0-0.71.1-1.4-0.8-1.20.6
Delay disc. indifference point, 0s delay1.71.93.8-2.0-1.6-1.51.51.51.5-1.51.51.5-1.51.5-1.51.41.4-1.4-1.81.41.41.4-1.4-1.40.9-1.20.7-0.30.00.2
Delay disc. indifference point, 16s delay0.10.10.40.50.20.3-0.3-0.3-0.30.3-0.3-0.30.3-0.20.3-0.3-0.20.30.3-0.3-0.2-0.30.30.3-0.30.2-0.4-0.6-0.40.3
Delay disc. indifference point, 2s delay0.60.71.3-0.9-0.8-0.80.80.80.8-0.80.80.8-0.90.9-0.90.90.9-0.9-0.50.80.91.0-0.9-1.00.8-1.11.10.30.4-0.4
Delay disc. indifference point, 24s delay0.30.40.7-0.8-0.7-0.70.60.60.6-0.60.60.7-0.70.7-0.60.90.6-0.6-0.90.60.60.7-0.7-0.70.6-0.70.4-0.4-0.30.3
Delay disc. indifference point, 4s delay3.23.44.7-2.1-2.2-2.02.02.02.0-2.02.02.0-2.02.1-2.01.92.0-2.0-1.82.02.02.0-1.9-2.01.7-1.91.3-0.10.4-0.1
Delay disc. indifference point, 8s delay1.52.53.7-1.9-1.8-1.81.81.81.8-1.81.81.8-1.71.7-1.71.71.6-1.6-1.81.71.61.7-1.6-1.51.5-1.30.80.50.6-0.3
Indifference point function ln k0.00.10.60.1-0.20.1-0.0-0.0-0.10.0-0.0-0.0-0.00.1-0.1-0.20.1-0.10.70.30.20.2-0.2-0.30.2-0.50.70.60.8-0.7
Indifference point function log k0.00.10.60.1-0.20.1-0.0-0.0-0.10.0-0.0-0.0-0.00.1-0.1-0.20.1-0.10.70.30.20.2-0.2-0.30.2-0.50.70.60.8-0.7
Patch foraging total patch changes 0 sec3.08.912.33.23.03.3-3.3-3.3-3.33.3-3.3-3.33.3-3.13.1-3.5-3.03.03.3-3.1-2.9-3.13.03.2-2.93.1-2.70.2-0.9-0.0
Patch foraging total patch changes 12 sec0.60.81.30.80.61.0-0.9-1.0-1.01.0-1.0-1.01.0-0.80.8-1.1-0.80.80.9-0.8-0.7-0.90.81.0-1.01.0-1.10.90.1-0.8
Patch foraging total patch changes 18 sec1.02.43.41.81.61.6-1.7-1.7-1.71.7-1.7-1.71.7-1.61.7-1.5-1.61.61.5-1.6-1.5-1.71.61.7-1.21.6-1.5-0.8-1.30.7
Patch foraging total patch changes 24 sec0.31.21.61.21.21.2-1.2-1.2-1.21.2-1.2-1.21.2-1.11.1-1.0-1.11.11.0-1.2-1.0-1.01.11.2-1.21.1-1.3-0.0-0.50.1
Patch foraging total patch changes 6 sec1.83.04.61.81.41.9-1.9-1.9-2.01.9-1.9-2.02.0-1.81.8-2.1-1.61.71.9-1.8-1.5-1.81.82.0-1.32.0-2.10.5-0.6-0.2
Patch foraging time to switch 0 sec0.93.55.7-2.4-1.7-2.32.12.22.2-2.22.22.2-2.21.8-1.72.21.6-1.6-2.41.81.71.8-1.7-1.91.4-1.62.0-0.40.10.6
Patch foraging water rate 0 sec0.83.06.32.51.52.2-2.1-2.1-2.12.1-2.0-2.12.0-1.61.6-2.0-1.51.52.5-1.5-1.6-1.71.51.6-1.01.1-1.60.3-0.1-0.5
Patch foraging water rate 12 sec1.45.711.63.02.52.9-2.8-2.8-2.82.7-2.7-2.72.7-2.52.4-2.6-2.32.33.4-2.2-2.4-2.32.22.2-1.81.8-1.31.00.3-0.9
Patch foraging water rate 18 sec0.20.41.71.00.61.0-0.9-0.8-0.90.8-0.8-0.80.8-0.40.4-0.8-0.40.41.3-0.3-0.5-0.60.30.3-0.3-0.10.00.40.6-0.5
Patch foraging water rate 24 sec0.20.21.90.3-0.20.3-0.2-0.2-0.30.2-0.2-0.20.20.1-0.1-0.20.1-0.10.50.3-0.00.2-0.3-0.20.3-0.50.21.41.2-1.0
Patch foraging water rate 6 sec0.40.51.81.10.51.0-0.9-0.9-0.90.9-0.9-0.90.8-0.60.6-0.7-0.60.61.4-0.4-0.7-0.60.60.5-0.40.3-0.30.70.3-0.7
Seeking ratio, delayed vs. immediate footshock0.20.31.60.3-0.10.00.00.10.1-0.10.10.2-0.20.5-0.50.50.5-0.50.40.20.50.5-0.5-0.80.7-1.21.3-0.90.1-0.0
Distance traveled before self-admin0.00.10.40.40.10.3-0.2-0.2-0.20.2-0.2-0.20.10.1-0.10.20.1-0.10.30.20.10.4-0.4-0.30.3-0.70.5-0.6-0.1-0.3
Distance traveled after self-admin0.10.10.9-0.5-0.4-0.30.30.20.3-0.30.30.2-0.20.2-0.20.30.2-0.3-0.30.30.30.6-0.4-0.10.2-0.00.00.60.6-0.9
Extensor digitorum longus weight0.52.23.2-1.2-1.5-1.51.51.51.5-1.51.51.5-1.61.7-1.71.51.7-1.7-1.21.51.71.6-1.6-1.71.6-1.81.50.20.7-0.1
Bone: elastic displacement0.40.61.4-1.1-0.7-1.00.90.90.9-0.90.90.9-0.90.7-0.71.00.6-0.6-1.20.50.60.9-0.7-0.70.7-0.50.50.10.20.2
Bone: elastic work1.21.62.6-1.6-1.3-1.51.51.41.5-1.41.41.4-1.41.2-1.31.41.2-1.2-1.61.21.31.3-1.3-1.21.4-1.00.80.30.60.1
Bone: endosteal estimation0.71.72.61.51.31.5-1.5-1.5-1.51.5-1.5-1.41.4-1.41.4-1.4-1.41.41.6-1.2-1.3-1.41.31.3-1.41.1-0.5-0.1-0.5-0.0
Bone: endosteal perimeter1.02.53.41.61.61.7-1.7-1.7-1.71.7-1.7-1.71.7-1.71.7-1.7-1.71.71.8-1.6-1.6-1.81.61.7-1.61.6-1.0-0.1-0.7-0.1
Epididymis fat weight0.00.20.7-0.1-0.6-0.40.50.50.5-0.50.50.5-0.50.5-0.50.30.6-0.6-0.40.60.60.5-0.5-0.50.6-0.60.2-0.8-0.10.4
Delta time in closed arm before/after self-admin0.20.20.30.40.50.5-0.5-0.5-0.50.4-0.4-0.50.4-0.40.4-0.5-0.40.40.6-0.5-0.5-0.40.30.4-0.30.3-0.50.30.5-0.5
Delta time in open arm before/after self-admin1.01.21.71.01.20.9-1.0-1.0-1.01.0-1.0-1.01.0-1.21.2-1.0-1.21.20.6-1.2-1.2-1.31.31.2-1.31.2-0.6-0.6-1.21.1
Diff in mean of infusions in LGA sessions0.00.10.40.50.30.4-0.3-0.3-0.30.3-0.3-0.30.3-0.20.2-0.3-0.20.10.6-0.3-0.20.0-0.10.10.1-0.0-0.10.00.3-0.5
Delay discount exponential model param1.21.62.11.41.41.4-1.4-1.4-1.41.4-1.4-1.41.4-1.41.4-1.4-1.31.31.3-1.3-1.3-1.41.31.3-1.21.2-0.80.0-0.20.1
Extinction: sum of active levers before priming0.50.72.3-0.2-0.5-0.50.60.60.6-0.60.60.6-0.60.7-0.80.70.8-0.80.30.90.80.8-0.9-0.91.2-1.11.21.21.5-1.5
Active lever presses in extinction session 60.20.21.20.70.20.5-0.4-0.4-0.40.4-0.4-0.40.4-0.20.2-0.4-0.10.10.9-0.0-0.1-0.1-0.10.10.2-0.10.10.50.6-1.1
Bone: final force0.20.31.3-0.4-0.6-0.40.50.40.4-0.40.40.4-0.50.5-0.50.20.5-0.50.30.70.60.3-0.6-0.50.7-0.60.81.20.9-0.8
Bone: final moment0.10.10.60.20.10.3-0.2-0.2-0.20.2-0.2-0.20.2-0.20.2-0.4-0.20.20.8-0.0-0.1-0.40.10.10.00.00.30.60.4-0.4
Food consumed during 24 hour testing period0.30.61.3-0.5-0.9-0.40.60.60.5-0.60.60.6-0.60.8-0.90.50.9-0.9-0.11.00.90.9-0.9-0.90.9-1.10.70.91.0-1.1
Glucose0.91.43.51.00.91.1-1.1-1.2-1.21.2-1.2-1.21.3-1.21.2-1.3-1.21.20.8-1.2-1.2-1.31.21.5-1.21.7-1.9-0.7-1.10.2
Heart weight1.62.53.1-1.6-1.8-1.71.71.71.7-1.71.71.7-1.71.7-1.71.41.7-1.7-1.41.71.71.7-1.7-1.61.5-1.51.01.41.5-1.1
Delay discount hyperbolic model param1.11.52.11.41.41.4-1.3-1.3-1.31.3-1.3-1.31.3-1.31.3-1.4-1.31.31.3-1.2-1.3-1.31.21.3-1.11.1-0.8-0.1-0.20.1
Intermittent access intake day 1-15 change0.21.22.3-1.5-1.3-1.31.21.21.2-1.21.21.2-1.21.1-1.11.11.1-1.1-1.50.91.11.1-1.3-1.01.2-0.80.4-0.2-0.20.3
Intermittent access intake escalation0.31.62.7-1.7-1.5-1.41.41.41.4-1.41.41.4-1.41.3-1.31.31.3-1.3-1.61.01.31.3-1.5-1.21.4-1.00.6-0.1-0.00.2
Intermittent access intake escalation 20.81.32.6-1.6-1.4-1.31.31.31.3-1.31.31.3-1.31.2-1.21.11.2-1.2-1.41.01.21.2-1.3-1.01.2-0.80.40.40.2-0.1
Intermitt. access day 1 inactive lever presses0.00.41.60.80.60.7-0.7-0.7-0.70.7-0.7-0.70.7-0.60.6-0.6-0.60.60.4-0.5-0.5-0.70.50.6-0.40.5-0.7-1.3-0.90.8
Intermitt. access day 15 inactive lever presses0.21.01.6-0.8-1.2-0.91.01.01.0-1.01.01.0-1.01.1-1.10.71.1-1.1-0.61.11.21.0-1.1-1.01.3-1.00.80.40.7-0.5
Intermitt. access escalation Index0.20.71.50.70.60.7-0.7-0.7-0.70.7-0.7-0.70.8-0.90.9-0.9-0.90.90.5-0.8-0.9-1.01.11.1-1.11.2-1.00.4-0.4-0.1
Intermittent access day 1 total infusions0.10.30.90.1-1.0-0.30.50.40.4-0.40.40.4-0.40.6-0.6-0.00.8-0.7-0.40.70.7-0.0-0.4-0.40.6-0.5-0.1-0.7-0.50.9
Intermittent access day 15 total infusions0.40.91.8-0.9-1.4-1.01.01.00.9-1.01.00.9-0.91.0-1.00.61.1-1.1-1.20.91.10.6-1.1-0.81.1-0.70.2-0.7-0.50.9
Intermittent access terminal intake (last 3 days)0.30.61.4-0.6-1.2-0.80.90.80.8-0.80.80.8-0.80.9-0.90.41.0-0.9-0.80.81.00.4-0.9-0.71.0-0.60.1-0.2-0.20.6
Intermittent access total infusions0.40.51.2-0.3-1.1-0.70.70.70.7-0.70.70.7-0.70.8-0.80.30.9-0.9-0.60.80.90.3-0.8-0.61.0-0.60.2-0.6-0.30.8
Intermittent access day 1 locomotion0.20.31.00.80.10.7-0.6-0.7-0.70.7-0.7-0.70.7-0.40.4-1.0-0.30.30.6-0.3-0.3-0.90.50.6-0.40.5-0.8-0.1-0.40.4
Intermittent access day 15 total locomotion0.00.11.20.2-0.40.2-0.1-0.2-0.20.2-0.2-0.30.3-0.10.1-0.90.00.00.2-0.10.0-0.40.10.5-0.00.6-1.10.5-0.1-0.0
Intermittent access total locomotion0.10.20.50.6-0.10.4-0.3-0.4-0.40.4-0.4-0.40.4-0.20.2-0.7-0.10.20.3-0.3-0.1-0.60.30.4-0.10.4-0.7-0.2-0.50.5
Intermittent access standard deviation0.10.61.4-1.0-1.1-0.90.90.90.8-0.90.90.8-0.80.8-0.80.60.8-0.8-1.20.90.80.6-1.0-0.70.8-0.60.0-0.6-0.20.7
Left kidney weight0.11.01.6-0.8-0.8-1.01.01.01.0-1.01.01.0-1.01.1-1.21.01.1-1.1-0.90.91.11.1-1.1-1.20.9-1.30.80.50.8-0.4
Right kidney weight0.21.12.1-0.5-0.8-0.80.90.90.9-0.90.90.9-0.91.2-1.20.91.2-1.2-0.61.01.21.3-1.1-1.30.7-1.51.11.21.4-0.7
Cocaine induced anxiety0.00.10.30.30.40.1-0.2-0.1-0.10.2-0.2-0.10.2-0.30.3-0.1-0.40.4-0.1-0.4-0.40.00.60.3-0.50.4-0.20.3-0.20.1
Post-drug Anxiety0.00.00.20.40.30.2-0.2-0.2-0.20.2-0.2-0.20.2-0.20.2-0.1-0.20.20.3-0.2-0.2-0.10.30.1-0.20.10.10.1-0.0-0.1
Baseline Anxiety0.00.00.20.1-0.10.2-0.1-0.1-0.10.1-0.1-0.10.10.1-0.0-0.20.1-0.10.30.10.1-0.3-0.2-0.00.3-0.1-0.1-0.4-0.00.1
Tail length0.31.32.2-1.5-1.2-1.51.41.41.4-1.41.41.4-1.31.1-1.11.31.0-1.0-1.11.21.01.1-1.0-1.11.0-0.81.00.70.6-0.3
Length with tail0.21.01.5-1.2-1.1-1.21.21.21.2-1.21.21.2-1.21.1-1.11.21.0-1.0-1.01.01.01.0-1.0-1.10.7-0.90.90.40.5-0.3
Length without tail0.00.20.5-0.2-0.3-0.30.30.30.3-0.30.30.4-0.40.5-0.50.40.5-0.5-0.10.40.50.4-0.5-0.60.3-0.70.60.30.4-0.4
Times rat made contact with spout0.00.00.20.30.10.3-0.2-0.2-0.20.2-0.2-0.20.2-0.10.1-0.3-0.00.00.2-0.2-0.0-0.10.00.1-0.00.1-0.40.20.1-0.1
Lifetime Intake0.40.51.2-0.4-1.1-0.70.80.70.7-0.70.70.7-0.70.8-0.80.30.9-0.9-0.60.80.90.3-0.8-0.61.0-0.60.3-0.4-0.10.6
Liver weight, left1.83.14.0-1.9-1.9-1.81.91.91.8-1.91.91.9-1.91.9-2.01.71.9-1.9-1.61.92.01.8-2.0-1.91.8-1.91.30.51.0-0.4
Liver weight, right1.72.93.9-1.9-1.9-1.81.81.81.8-1.81.81.8-1.81.9-2.01.81.9-1.9-1.91.81.91.9-1.9-1.81.5-1.80.9-0.40.7-0.0
Locomotor activity0.10.21.10.10.20.3-0.3-0.3-0.30.3-0.3-0.30.3-0.20.2-0.4-0.20.20.5-0.1-0.2-0.20.40.2-0.80.20.11.10.7-0.8
Locomotor testing distance0.82.14.11.61.51.7-1.6-1.6-1.61.6-1.6-1.61.6-1.41.3-1.6-1.41.42.0-1.3-1.4-1.41.61.3-2.01.1-0.50.70.2-0.6
Locomotor testing rearing0.00.10.8-0.5-0.3-0.20.20.20.2-0.20.20.2-0.20.3-0.40.20.3-0.3-0.20.20.20.5-0.3-0.3-0.2-0.30.10.90.7-0.8
Locomotion in novel chamber1.11.52.11.21.41.2-1.2-1.2-1.21.2-1.2-1.31.3-1.41.4-1.2-1.41.41.3-1.5-1.3-1.21.31.4-1.11.5-1.10.1-0.2-0.2
Locomotion in novel chamber post-restriction0.00.00.40.10.10.1-0.1-0.1-0.10.1-0.1-0.10.1-0.10.1-0.0-0.10.10.40.2-0.1-0.1-0.1-0.1-0.1-0.20.40.40.3-0.6
Fecal boli incidents, locomotor time 10.00.00.1-0.2-0.2-0.00.00.00.0-0.0-0.0-0.00.0-0.10.1-0.1-0.10.1-0.1-0.2-0.1-0.30.00.2-0.10.4-0.20.2-0.10.0
Change in fecal boli incidents, locomotor task0.10.10.4-0.1-0.2-0.20.30.20.3-0.30.30.3-0.30.4-0.40.20.4-0.40.10.40.40.3-0.3-0.40.4-0.50.60.30.5-0.2
Time >=10cm from walls, locomotor time 10.00.10.30.30.40.2-0.2-0.2-0.20.2-0.2-0.20.2-0.20.3-0.2-0.30.20.2-0.5-0.3-0.00.10.2-0.10.20.1-0.3-0.30.2
Bouts of movement, locomotor time 10.20.32.00.10.30.4-0.4-0.4-0.40.4-0.4-0.40.4-0.40.4-0.5-0.40.40.5-0.3-0.4-0.30.30.4-0.40.4-0.41.40.7-0.9
Total resting periods, locomotor time 10.20.32.50.20.30.4-0.4-0.4-0.40.4-0.4-0.40.4-0.40.3-0.5-0.30.30.6-0.3-0.3-0.30.20.4-0.20.4-0.41.60.7-0.9
Rest time, locomotor task time 10.10.20.90.20.40.4-0.4-0.4-0.40.4-0.4-0.40.4-0.40.4-0.5-0.40.40.4-0.4-0.4-0.40.30.5-0.40.5-0.50.90.2-0.4
Distance moved, locomotor task time 10.00.10.50.00.1-0.20.10.20.2-0.20.20.2-0.20.00.00.3-0.10.1-0.50.1-0.10.30.1-0.2-0.2-0.10.6-0.7-0.30.5
Vertical activity count, locomotor time 10.00.20.70.80.60.5-0.5-0.5-0.50.5-0.5-0.40.5-0.60.6-0.3-0.60.60.4-0.2-0.6-0.40.80.4-0.80.3-0.0-0.4-0.20.2
Time >=10cm from walls, locomotor time 21.02.95.4-1.5-1.3-1.61.61.71.7-1.61.71.7-1.71.5-1.61.81.6-1.6-1.01.61.62.0-1.8-1.81.9-1.82.32.01.9-1.5
Bouts of movement, locomotor time 20.41.32.00.91.21.3-1.3-1.3-1.31.3-1.3-1.31.3-1.11.1-1.3-1.11.11.4-1.2-1.1-1.10.81.2-0.91.0-1.11.00.2-0.7
Total resting periods, locomotor time 20.31.31.90.91.21.4-1.3-1.3-1.31.3-1.3-1.41.3-1.21.1-1.4-1.11.11.4-1.3-1.1-1.10.91.2-0.91.1-1.20.70.0-0.5
Rest time, locomotor task time 20.30.51.70.40.60.7-0.7-0.7-0.70.7-0.7-0.70.7-0.70.7-0.9-0.60.60.3-0.8-0.6-0.90.60.9-0.51.0-1.3-0.4-0.60.7
Distance moved, locomotor task time 20.91.22.3-1.1-0.8-1.21.11.21.2-1.21.21.2-1.21.0-1.01.40.9-0.9-1.11.20.91.4-0.9-1.20.7-1.21.50.70.9-0.7
Vertical activity count, locomotor time 20.10.21.0-0.1-0.2-0.30.30.40.4-0.40.40.4-0.40.3-0.30.50.3-0.3-0.00.60.30.6-0.2-0.50.1-0.61.00.90.8-0.9
Light reinforcement 10.10.60.9-0.9-1.0-0.90.90.90.9-0.90.90.9-0.80.8-0.70.80.8-0.8-0.80.90.80.6-0.7-0.60.9-0.40.50.1-0.20.0
Light reinforcement 20.10.20.6-0.8-0.6-0.60.50.50.5-0.50.50.5-0.50.4-0.40.50.4-0.4-0.50.50.40.4-0.5-0.30.5-0.20.20.3-0.0-0.3
Bone: marrow area0.61.52.41.41.21.4-1.4-1.4-1.41.4-1.4-1.41.4-1.31.3-1.3-1.31.31.5-1.1-1.2-1.31.21.2-1.31.0-0.5-0.1-0.4-0.0
Bone: maximum diameter0.61.22.31.20.91.2-1.2-1.2-1.21.2-1.2-1.21.2-1.11.1-1.4-1.01.11.5-0.9-0.9-1.31.01.1-0.91.0-0.80.60.1-0.5
Bone: maximum force0.00.10.40.20.10.1-0.1-0.1-0.10.1-0.1-0.10.1-0.10.1-0.3-0.10.10.70.20.1-0.2-0.1-0.00.2-0.20.50.70.6-0.5
Bone: maximum moment0.30.51.50.90.80.8-0.8-0.8-0.80.8-0.8-0.80.8-0.80.8-0.9-0.80.81.2-0.6-0.6-0.90.60.6-0.50.50.00.20.1-0.1
Mean time between licks in bursts1.37.910.4-3.2-3.1-3.13.13.13.1-3.13.13.1-3.13.0-2.93.12.9-2.9-3.12.82.92.8-2.9-2.92.7-2.62.5-0.9-0.10.6
Mean num. licks in bursts0.00.10.40.20.40.2-0.2-0.2-0.20.2-0.2-0.20.2-0.40.4-0.4-0.40.4-0.0-0.4-0.4-0.40.40.4-0.30.6-0.6-0.5-0.30.4
Cd content in liver1.61.82.91.41.31.5-1.5-1.5-1.51.5-1.5-1.51.5-1.41.4-1.5-1.41.41.7-1.4-1.4-1.41.41.4-1.41.3-0.6-0.0-0.4-0.2
Co content in liver0.10.10.80.10.00.0-0.00.0-0.0-0.00.00.1-0.10.0-0.10.00.0-0.10.20.30.10.2-0.0-0.3-0.2-0.50.90.90.7-0.7
Cu content in liver0.70.81.4-0.7-0.9-0.80.80.80.8-0.80.80.8-0.91.0-0.90.81.0-1.0-0.41.01.00.7-1.0-1.01.0-1.11.0-1.2-0.70.6
Fe content in liver0.00.10.20.30.10.3-0.2-0.2-0.20.2-0.2-0.20.1-0.00.1-0.1-0.00.00.4-0.1-0.00.00.0-0.10.1-0.30.3-0.4-0.40.5
K content in liver1.91.82.8-1.7-1.4-1.51.51.51.5-1.51.51.5-1.51.4-1.41.51.4-1.4-1.61.51.41.3-1.4-1.31.5-1.10.7-0.6-0.30.8
Mg content in liver0.30.41.70.40.50.4-0.4-0.4-0.40.4-0.4-0.40.4-0.40.5-0.4-0.50.50.2-0.4-0.5-0.70.60.5-0.60.5-0.3-1.2-1.31.3
Mn content in liver0.00.10.4-0.10.1-0.10.00.00.1-0.00.00.1-0.0-0.10.10.3-0.10.1-0.5-0.1-0.1-0.00.10.10.00.2-0.0-0.4-0.50.7
Na content in liver3.54.05.8-2.4-2.2-2.32.22.22.2-2.22.22.2-2.22.1-2.12.12.1-2.1-2.21.92.12.1-2.1-1.92.3-1.71.10.20.40.1
Rb content in liver0.60.71.0-0.9-1.0-1.01.01.01.0-1.01.01.0-1.00.9-0.80.90.8-0.8-0.90.90.80.7-0.6-0.90.4-0.81.00.20.20.1
Se content in liver0.30.31.30.80.80.7-0.6-0.6-0.60.6-0.6-0.60.6-0.50.5-0.5-0.50.51.1-0.3-0.4-0.40.30.3-0.10.10.1-0.9-0.70.3
Sr content in liver0.90.81.10.80.90.9-0.9-0.9-0.90.9-0.9-0.90.9-1.01.0-0.8-1.01.00.4-1.1-1.0-0.91.00.9-0.81.0-0.8-0.3-0.60.4
Zn content in liver1.61.92.91.61.41.5-1.5-1.5-1.51.5-1.5-1.51.5-1.41.4-1.6-1.31.31.7-1.2-1.3-1.51.31.4-1.11.3-1.0-1.1-1.30.8
Bone: minimum diameter1.32.43.71.61.91.5-1.6-1.6-1.51.6-1.6-1.61.6-1.81.8-1.5-1.91.91.5-1.7-1.8-1.81.71.6-1.71.6-0.6-0.8-0.80.7
Time in familiar zone, hab. session 12.32.54.2-1.2-1.5-1.31.41.41.4-1.41.51.5-1.51.7-1.81.51.7-1.7-0.51.71.71.6-1.7-1.81.6-2.02.01.61.9-1.4
Time in novel zone, hab. session 15.15.77.02.42.62.4-2.5-2.5-2.52.5-2.5-2.52.5-2.62.6-2.3-2.62.61.8-2.6-2.6-2.52.52.6-2.52.6-2.3-1.4-1.81.2
Total zone transitions, hab. session 12.13.04.2-1.7-1.6-1.81.81.81.8-1.81.81.8-1.81.7-1.81.71.7-1.7-1.61.91.72.0-1.8-1.81.7-1.81.41.71.8-1.3
Total locomotion distance, hab. session 10.40.52.4-0.4-0.5-0.40.50.50.5-0.50.50.5-0.50.6-0.70.40.6-0.6-0.10.60.60.7-0.7-0.70.7-0.80.81.51.5-1.3
Locomotion velocity, hab. session 10.30.50.9-0.6-0.7-0.60.70.70.6-0.70.70.7-0.70.7-0.70.50.7-0.7-0.50.70.70.7-0.7-0.70.6-0.70.50.81.0-0.8
Time in familiar zone, hab. session 20.30.40.8-0.5-0.6-0.50.60.60.6-0.60.60.6-0.60.7-0.70.70.7-0.7-0.30.70.70.6-0.8-0.80.7-0.90.6-0.40.20.0
Time in novel zone, hab. session 20.70.71.20.81.00.8-0.9-0.9-0.90.9-0.9-0.90.9-1.00.9-0.9-1.01.00.7-1.1-1.0-0.81.01.0-0.91.1-0.70.70.0-0.3
Total zone transitions, hab. session 25.57.19.0-2.7-2.8-2.82.82.82.8-2.82.82.8-2.82.9-2.92.72.8-2.9-2.22.72.83.0-2.8-2.82.8-2.72.31.71.9-1.4
Total locomotion distance, hab. session 22.83.74.4-1.9-1.9-2.02.02.02.0-2.02.02.0-2.02.0-2.11.92.1-2.1-1.31.82.02.1-2.0-2.02.1-2.01.91.51.7-1.3
Locomotion velocity, hab. session 22.53.33.9-1.8-1.8-1.91.91.91.9-1.91.91.9-1.91.9-2.01.81.9-2.0-1.21.81.92.0-1.9-1.91.9-1.91.91.41.6-1.3
Novel to familiar place preference ratio1.11.42.21.41.11.4-1.4-1.4-1.41.4-1.4-1.41.4-1.21.2-1.5-1.11.21.1-1.4-1.1-1.31.21.2-1.21.0-1.00.4-0.0-0.1
Novelty place preference0.81.01.61.20.91.2-1.2-1.2-1.21.2-1.2-1.21.1-1.01.0-1.3-0.91.00.9-1.2-0.9-1.11.01.0-1.00.8-0.80.3-0.0-0.0
Time in novel zone, NPP test1.21.42.21.41.21.4-1.4-1.4-1.41.4-1.4-1.41.4-1.21.2-1.4-1.21.21.1-1.5-1.1-1.21.21.2-1.21.0-0.90.2-0.10.0
Total zone transitions, NPP test1.92.94.7-1.5-1.7-1.71.71.71.7-1.71.71.7-1.71.7-1.71.41.7-1.7-1.01.71.71.9-1.7-1.71.7-1.61.52.21.9-1.8
Total locomotion distance, NPP test0.40.62.7-0.3-0.6-0.50.60.60.6-0.60.60.6-0.60.7-0.70.30.7-0.70.10.60.70.7-0.7-0.70.8-0.81.01.61.4-1.4
Locomotion velocity, NPP test0.71.02.7-0.6-0.9-0.80.80.80.8-0.80.80.8-0.90.9-1.00.61.0-1.0-0.10.91.00.9-0.9-1.01.0-1.01.21.61.5-1.4
Intraocular pressure0.30.53.10.60.50.6-0.5-0.5-0.60.5-0.5-0.50.5-0.50.4-0.4-0.40.41.0-0.2-0.4-0.10.30.3-0.30.00.21.81.4-1.5
Delta distance traveled before/after self-admin0.20.21.0-0.2-0.0-0.10.0-0.0-0.00.0-0.0-0.10.1-0.40.3-0.4-0.40.4-0.5-0.1-0.4-0.40.50.6-0.61.0-0.90.4-0.10.3
Delta ambulatory time before/after self-admin0.10.10.5-0.5-0.3-0.30.30.20.3-0.20.20.2-0.2-0.10.0-0.1-0.10.1-0.60.2-0.1-0.10.20.3-0.30.7-0.70.50.00.1
Parametrial fat weight6.314.917.94.24.14.1-4.2-4.2-4.14.2-4.2-4.14.1-4.04.1-3.9-4.04.03.5-4.1-4.0-3.94.04.0-3.93.8-3.1-2.4-2.91.7
Pavlov. Cond. lever latency0.50.61.9-1.1-0.6-0.90.80.90.9-0.80.80.8-0.80.6-0.60.90.5-0.5-1.40.50.50.6-0.6-0.60.5-0.30.2-1.2-0.91.2
Pavlov. Cond. magazine entry latency0.40.51.3-0.6-0.6-0.70.70.70.7-0.70.70.7-0.70.7-0.70.50.7-0.7-0.20.50.70.6-0.6-0.60.6-0.50.61.21.0-0.9
Pavlov. Cond. change in total contacts0.50.60.70.80.80.8-0.8-0.8-0.80.8-0.8-0.80.8-0.80.8-0.8-0.80.80.6-0.8-0.8-0.80.80.8-0.80.8-0.7-0.5-0.50.4
Pavlov. Cond. index score0.10.21.40.30.10.3-0.2-0.2-0.20.2-0.2-0.20.2-0.10.1-0.4-0.00.00.8-0.1-0.1-0.10.20.20.00.10.11.20.8-1.0
Pavlov. Cond. latency score0.30.32.50.50.20.5-0.4-0.4-0.40.4-0.4-0.40.4-0.20.2-0.6-0.10.11.2-0.2-0.2-0.20.20.3-0.10.10.11.61.1-1.4
Pavlov. Cond. lever contacts0.20.21.00.50.20.4-0.4-0.4-0.40.4-0.4-0.40.4-0.20.2-0.4-0.20.20.8-0.1-0.2-0.20.30.3-0.20.1-0.20.90.7-1.0
Pavlov. Cond. magazine entry number0.50.61.00.90.90.8-0.9-0.8-0.80.8-0.8-0.80.8-0.80.9-0.6-0.90.90.4-0.8-0.9-0.80.80.7-0.90.6-0.4-1.0-0.90.8
Pavlov. Cond. intertrial magazine entries0.91.03.2-1.2-1.0-1.21.11.11.1-1.11.11.1-1.00.9-0.91.00.9-0.9-1.80.80.90.8-0.8-0.80.8-0.5-0.0-1.4-0.91.2
Pavlov. Cond. lever-magazine prob. diff.0.10.21.00.40.30.4-0.3-0.3-0.30.3-0.3-0.30.3-0.20.2-0.5-0.20.20.9-0.2-0.2-0.30.30.3-0.20.3-0.11.00.7-0.9
Pavlov. Cond. response bias0.10.20.2-0.4-0.4-0.40.40.40.4-0.40.40.4-0.40.4-0.40.40.4-0.4-0.30.40.50.4-0.4-0.40.4-0.30.20.40.4-0.4
Pavlov. Cond. lever latency1.62.23.1-1.6-1.8-1.51.51.51.5-1.51.51.5-1.51.6-1.61.41.6-1.6-1.31.81.51.6-1.5-1.51.3-1.50.91.61.3-1.1
Pavlov. Cond. magazine entry latency1.21.72.51.11.51.2-1.3-1.2-1.21.3-1.3-1.21.3-1.41.4-1.2-1.51.51.0-1.5-1.5-1.61.41.4-1.31.4-0.8-1.4-1.41.1
Pavlov. Cond. change in total contacts0.82.03.91.41.61.3-1.4-1.4-1.31.4-1.4-1.31.3-1.51.5-1.2-1.51.51.1-1.7-1.5-1.61.51.4-1.31.4-0.8-2.0-1.61.4
Pavlov. Cond. index score1.01.63.11.11.51.1-1.2-1.2-1.21.2-1.2-1.21.2-1.31.3-1.0-1.41.41.0-1.5-1.3-1.51.31.2-1.11.3-0.6-1.8-1.51.2
Pavlov. Cond. latency score0.81.42.21.11.41.1-1.1-1.1-1.11.1-1.1-1.11.1-1.21.2-1.0-1.31.31.0-1.4-1.2-1.31.21.1-1.01.2-0.6-1.5-1.31.0
Pavlov. Cond. lever contacts1.62.33.11.61.81.5-1.5-1.5-1.51.5-1.5-1.51.5-1.61.6-1.4-1.71.71.3-1.8-1.5-1.71.51.5-1.31.5-0.9-1.7-1.41.2
Pavlov. Cond. magazine entry number0.50.72.6-0.6-0.9-0.60.70.70.6-0.70.70.7-0.70.8-0.80.70.8-0.9-0.51.00.81.0-0.8-0.80.7-0.90.41.61.3-1.2
Pavlov. Cond. intertrial magazine entries0.92.03.9-1.8-1.3-1.71.61.61.7-1.61.61.6-1.61.4-1.41.71.4-1.4-2.01.21.41.7-1.4-1.31.2-0.90.90.60.4-0.0
Pavlov. Cond. lever-magazine prob. diff.1.11.83.61.21.51.2-1.3-1.2-1.21.2-1.2-1.21.2-1.41.4-1.1-1.41.41.0-1.6-1.4-1.51.41.3-1.21.3-0.7-1.9-1.61.3
Pavlov. Cond. response bias1.31.94.31.31.61.1-1.2-1.2-1.21.2-1.2-1.21.2-1.41.4-1.1-1.51.50.9-1.6-1.4-1.51.41.3-1.21.4-0.7-2.1-1.71.5
Time in closed arm before self-admin0.10.20.5-0.4-0.7-0.30.30.30.3-0.30.30.3-0.30.5-0.50.30.6-0.5-0.30.70.60.2-0.4-0.50.2-0.60.5-0.6-0.30.5
Time in closed arm after self-admin0.00.00.20.3-0.10.3-0.2-0.2-0.30.2-0.2-0.20.20.1-0.1-0.10.1-0.10.40.10.1-0.20.0-0.2-0.1-0.50.3-0.5-0.00.1
Time in open arm before self-admin0.10.21.6-0.2-0.0-0.10.20.10.1-0.10.10.1-0.10.1-0.10.00.0-0.1-0.0-0.1-0.10.4-0.20.10.20.2-0.51.20.9-1.3
Time in open arm after self-admin1.71.83.51.11.41.2-1.3-1.3-1.31.3-1.3-1.31.4-1.51.5-1.5-1.51.51.0-1.7-1.6-1.51.51.7-1.41.9-1.40.4-0.70.2
Bone: periosteal estimation0.61.52.31.41.31.4-1.3-1.3-1.31.3-1.3-1.31.3-1.41.3-1.4-1.41.41.5-1.2-1.2-1.41.21.2-1.21.0-0.50.0-0.2-0.0
Bone: periosteal perimeter0.40.81.20.70.90.8-0.9-0.9-0.90.9-0.9-0.90.9-1.11.1-1.0-1.11.10.9-0.9-1.0-1.11.01.0-0.81.1-0.5-0.3-0.60.2
Bone: post-yield work1.22.14.72.11.71.7-1.7-1.7-1.71.7-1.7-1.61.6-1.51.5-1.7-1.51.52.2-1.2-1.4-1.51.41.3-1.21.0-0.4-0.2-0.0-0.2
Progressive ratio test 1 active lever presses0.50.82.0-0.6-1.4-0.91.11.01.0-1.01.00.9-0.91.1-1.10.51.2-1.2-0.71.11.20.5-0.9-0.81.1-0.70.40.30.30.0
Progressive ratio test 1 breakpoint0.71.12.5-0.8-1.6-1.11.21.11.1-1.21.21.1-1.11.3-1.30.61.4-1.3-0.81.31.40.7-1.1-1.01.3-0.90.50.30.4-0.0
Progressive ratio test 1 inactive lever presses0.71.83.5-1.4-1.9-1.51.51.51.5-1.51.51.4-1.41.6-1.61.01.6-1.6-1.41.51.71.0-1.3-1.21.4-1.00.40.20.20.2
Progressive ratio test 2 active lever presses0.00.10.5-0.0-0.40.00.1-0.0-0.0-0.0-0.0-0.00.10.1-0.1-0.50.1-0.10.10.10.1-0.3-0.10.20.10.3-0.60.70.1-0.1
Progressive ratio test 2 breakpoint0.10.10.5-0.2-0.5-0.10.20.10.1-0.10.10.1-0.10.2-0.2-0.30.3-0.3-0.00.20.3-0.1-0.30.10.20.2-0.50.70.2-0.1
Progressive ratio test 2 inactive lever presses0.10.31.2-0.5-1.1-0.50.60.50.5-0.50.50.5-0.50.6-0.6-0.10.7-0.6-0.60.80.70.0-0.5-0.20.4-0.1-0.70.60.10.1
Incentive Sensitization - Responses0.20.51.50.30.30.7-0.6-0.7-0.70.7-0.7-0.70.7-0.60.6-1.0-0.60.60.6-0.6-0.6-0.80.60.9-0.80.9-1.21.20.2-0.5
Incentive Sensitization - Breakpoint0.30.61.50.30.40.7-0.7-0.7-0.70.7-0.7-0.80.8-0.70.7-1.0-0.70.70.6-0.7-0.7-0.80.60.9-0.91.0-1.21.10.1-0.4
Sum of active levers in priming session hrs 5-61.01.02.3-0.5-0.8-0.60.70.70.7-0.80.80.8-0.81.0-1.10.81.1-1.10.01.21.10.9-1.2-1.21.3-1.51.50.81.3-1.2
Progressive ratio0.41.11.6-1.3-1.1-1.31.21.21.2-1.21.21.2-1.11.2-1.21.11.2-1.2-1.10.71.21.0-1.1-0.91.2-0.60.30.00.4-0.3
Food seeking constrained by brief footshock3.64.65.7-2.2-2.2-2.32.32.32.3-2.32.32.4-2.42.3-2.32.32.3-2.2-2.22.42.22.1-2.1-2.31.9-2.32.1-0.10.70.1
Seeking ratio, punishment vs. effort0.20.41.1-0.5-0.6-0.50.50.60.6-0.60.60.6-0.60.5-0.60.50.5-0.5-0.61.00.50.6-0.6-0.80.2-1.01.00.00.10.3
Retroperitoneal fat weight0.20.91.71.31.01.1-1.1-1.1-1.11.1-1.1-1.11.1-0.90.9-1.1-0.80.81.2-1.0-0.7-0.70.90.9-0.70.8-0.7-0.6-0.50.3
Reaction time number correct0.10.22.10.10.10.2-0.1-0.1-0.10.1-0.1-0.10.10.0-0.10.00.1-0.10.3-0.00.00.2-0.1-0.0-0.0-0.2-0.11.51.3-1.1
Reaction time mean minus median0.00.21.9-0.20.1-0.20.10.10.1-0.10.10.1-0.1-0.00.10.3-0.10.1-0.5-0.3-0.1-0.00.20.0-0.20.2-0.1-1.4-1.01.0
Reaction time mean minus median AUC0.00.20.4-0.5-0.3-0.40.40.40.4-0.40.40.4-0.40.3-0.30.60.3-0.3-0.50.20.30.3-0.2-0.30.2-0.20.4-0.7-0.40.5
Reaction time num false alarms0.10.21.5-0.30.20.0-0.1-0.1-0.10.1-0.1-0.20.2-0.30.3-0.3-0.40.4-0.3-0.5-0.4-0.30.30.6-0.50.9-1.2-0.3-0.50.3
Reaction time num false alarms AUC0.30.72.90.20.70.5-0.6-0.6-0.60.6-0.6-0.70.7-0.80.8-0.8-0.90.9-0.0-1.0-0.9-0.90.81.1-1.11.4-1.7-0.7-1.00.8
Reaction time trials correct on left0.10.22.10.10.10.2-0.1-0.1-0.10.1-0.1-0.10.10.0-0.10.00.1-0.10.3-0.00.00.2-0.1-0.0-0.0-0.2-0.11.51.3-1.1
Reaction time trials on left0.10.22.10.20.10.3-0.2-0.2-0.20.2-0.2-0.20.2-0.0-0.1-0.1-0.00.00.3-0.1-0.10.1-0.10.0-0.1-0.1-0.11.41.2-1.1
Reaction time mean0.40.82.80.91.00.7-0.8-0.8-0.70.8-0.8-0.70.7-0.91.0-0.5-1.01.00.3-1.0-1.0-0.70.90.7-0.90.8-0.3-1.7-1.21.1
Reaction time mean AUC0.20.42.90.60.70.4-0.4-0.4-0.40.4-0.4-0.40.4-0.50.6-0.1-0.60.6-0.0-0.6-0.6-0.30.50.3-0.50.3-0.0-1.7-1.01.1
Median of all reaction times0.71.22.21.21.31.0-1.1-1.1-1.01.1-1.1-1.01.0-1.21.2-0.8-1.21.20.7-1.2-1.2-1.01.11.0-1.10.9-0.4-1.5-1.11.0
Reaction time omissions1.32.13.51.41.41.4-1.4-1.4-1.41.4-1.4-1.51.5-1.51.5-1.5-1.51.50.8-1.5-1.6-1.51.61.6-1.81.7-1.9-0.9-1.20.6
Reaction time false alarm rate0.71.02.50.30.80.5-0.7-0.7-0.60.7-0.7-0.70.8-1.01.0-0.9-1.01.10.1-1.1-1.0-1.11.01.2-1.21.5-1.5-1.5-1.61.2
Reaction time premature initiation rate0.40.61.4-0.7-0.7-0.70.70.70.7-0.70.70.7-0.70.6-0.70.80.6-0.7-1.20.80.81.0-0.8-0.70.7-0.70.41.00.8-0.5
Reaction time premature initiations0.31.02.4-0.8-0.9-0.80.80.90.8-0.90.90.9-0.90.9-1.01.00.9-0.9-1.21.01.01.2-1.0-1.00.9-1.00.61.61.4-0.9
Std. dev. reaction times0.31.12.61.01.20.8-1.0-0.9-0.90.9-0.9-0.90.9-1.11.1-0.7-1.21.20.5-1.2-1.2-0.91.21.0-1.11.1-0.6-1.6-1.31.1
Reaction time trials completed0.10.22.10.20.10.3-0.2-0.2-0.20.2-0.2-0.20.2-0.0-0.1-0.1-0.00.00.3-0.1-0.10.1-0.10.0-0.1-0.1-0.11.41.2-1.1
Reaction time trials AUC0.10.22.00.10.10.2-0.2-0.2-0.20.2-0.2-0.20.2-0.0-0.1-0.0-0.0-0.00.3-0.1-0.10.1-0.10.0-0.1-0.1-0.11.41.2-1.1
Run reversals in cocaine runway, females0.10.11.6-0.2-0.3-0.10.10.10.1-0.10.10.1-0.10.0-0.1-0.10.0-0.00.10.2-0.10.00.10.1-0.20.2-0.21.30.7-1.0
Run reversals in cocaine runway, males0.30.30.60.70.80.4-0.5-0.5-0.50.5-0.5-0.50.5-0.70.7-0.5-0.70.70.5-0.7-0.7-0.70.70.7-0.50.8-0.4-0.3-0.40.2
Latency to leave start box in cocaine runway0.20.31.5-0.3-0.1-0.20.20.20.2-0.20.20.2-0.30.3-0.30.40.3-0.30.30.40.30.5-0.4-0.50.3-0.70.81.21.1-1.1
Latency to leave start box in cocaine runway, F0.20.21.00.20.70.4-0.4-0.4-0.40.4-0.4-0.40.4-0.50.4-0.3-0.50.40.6-0.5-0.4-0.20.30.4-0.40.3-0.11.00.8-0.9
Latency to leave start box in cocaine runway, M0.40.41.3-0.6-0.6-0.50.50.60.6-0.60.60.6-0.60.6-0.60.80.6-0.6-0.10.90.60.6-0.6-0.80.6-1.01.20.40.3-0.4
Std. dev. time between licks in bursts0.10.23.6-0.1-0.1-0.0-0.00.0-0.0-0.00.00.0-0.00.00.00.1-0.00.0-0.30.1-0.0-0.10.0-0.1-0.1-0.10.1-1.9-1.31.1
Total sessions with >9 infusions1.31.62.8-1.2-1.7-1.21.31.21.2-1.21.21.2-1.21.4-1.40.81.6-1.5-0.71.31.61.0-1.4-1.11.5-1.00.81.21.2-1.0
Short access day 1 total inactive lever presses0.00.00.1-0.1-0.20.0-0.0-0.0-0.00.0-0.0-0.00.00.1-0.1-0.10.1-0.0-0.30.00.1-0.2-0.10.0-0.10.0-0.3-0.3-0.20.4
Short access day 10 total inactive lever presses0.21.72.21.31.51.4-1.4-1.4-1.41.4-1.4-1.41.4-1.51.4-1.4-1.51.51.3-1.3-1.4-1.31.41.4-1.41.3-1.00.60.1-0.6
Short access day 1 total infusions0.10.20.5-0.5-0.5-0.40.40.40.4-0.40.40.4-0.40.5-0.50.20.5-0.5-0.00.20.60.2-0.6-0.20.7-0.20.20.20.3-0.2
Short access day 10 total infusions0.30.51.2-0.4-1.1-0.60.70.60.6-0.70.70.6-0.60.8-0.80.21.0-1.0-0.11.01.00.3-0.8-0.61.1-0.70.40.40.6-0.2
Short access total infusions0.20.20.8-0.2-0.8-0.40.50.50.5-0.50.50.4-0.50.6-0.60.10.7-0.6-0.10.60.70.2-0.6-0.40.9-0.30.30.00.20.0
Short access day 1 locomotion0.10.10.7-0.4-0.00.1-0.0-0.1-0.10.1-0.1-0.20.2-0.10.1-0.5-0.10.10.3-0.3-0.0-0.3-0.20.50.20.7-0.70.90.5-0.6
Short access day 10 total locomotion0.31.32.41.20.81.4-1.2-1.3-1.31.3-1.3-1.31.3-1.11.1-1.6-1.01.01.4-0.9-0.9-1.41.01.2-0.91.1-1.3-0.2-0.40.1
Short access total locomotion0.10.10.8-0.2-0.50.00.10.0-0.0-0.00.0-0.00.00.2-0.2-0.40.3-0.30.30.20.4-0.1-0.40.10.40.1-0.40.90.6-0.6
One hour access (0.3 mA shock)0.10.10.3-0.6-0.4-0.40.40.40.4-0.40.40.4-0.40.3-0.30.00.3-0.3-0.30.30.3-0.0-0.5-0.20.5-0.00.0-0.0-0.00.4
Compulsive drug intake3.34.97.82.12.82.2-2.4-2.3-2.32.3-2.3-2.32.3-2.52.5-2.0-2.62.61.8-2.5-2.6-2.32.52.3-2.62.3-1.5-0.2-0.60.2
One hour access (shock baseline)1.02.74.6-1.7-2.1-1.71.81.81.8-1.81.81.7-1.71.8-1.81.21.9-1.9-1.41.91.91.4-1.9-1.62.0-1.40.9-0.20.10.6
Social response proportion1.31.63.21.01.21.1-1.2-1.2-1.21.2-1.2-1.21.2-1.41.4-1.3-1.41.40.6-1.4-1.5-1.41.41.5-1.81.6-1.2-0.9-1.20.6
Social responses0.10.20.9-0.5-0.4-0.60.50.50.5-0.50.50.5-0.50.3-0.30.20.3-0.3-1.00.30.10.2-0.2-0.1-0.10.2-0.1-0.4-0.40.2
Social time0.30.51.70.30.30.4-0.4-0.4-0.40.5-0.5-0.50.5-0.60.7-0.6-0.70.7-0.2-0.8-0.7-0.70.90.9-1.21.2-1.1-1.1-1.30.6
Soleus weight0.20.61.3-0.8-0.4-0.90.80.80.8-0.80.80.8-0.80.7-0.71.00.6-0.7-0.70.50.70.8-0.7-0.80.7-0.81.20.40.5-0.0
Bone: stiffness0.10.10.90.2-0.10.2-0.1-0.1-0.10.1-0.1-0.10.10.0-0.1-0.30.1-0.10.70.20.20.0-0.2-0.10.2-0.20.21.00.7-0.9
Tibialis anterior weight7.325.131.65.65.45.5-5.5-5.5-5.55.5-5.5-5.55.5-5.35.3-5.5-5.25.25.4-5.3-5.2-5.35.25.1-5.24.8-3.4-0.9-2.00.5
Time to tail flick, vehicle, before self-admin0.81.02.31.21.01.1-1.1-1.1-1.11.1-1.1-1.11.1-1.01.0-1.1-1.01.01.5-1.1-1.0-1.01.21.0-1.00.9-0.60.50.1-0.6
Time to tail flick, vehicle, after self-admin0.51.01.31.01.01.1-1.1-1.1-1.11.1-1.1-1.11.1-1.11.1-1.0-1.11.10.9-1.0-1.1-1.01.01.0-1.21.0-0.70.1-0.40.0
Time to tail flick, test, before self-admin0.10.10.70.2-0.00.1-0.1-0.1-0.10.1-0.1-0.10.1-0.10.1-0.3-0.10.1-0.10.0-0.1-0.60.20.2-0.20.2-0.3-0.6-0.60.8
Time to tail flick, test, after self-admin0.20.30.8-0.2-0.6-0.40.40.40.4-0.40.40.4-0.40.5-0.40.40.5-0.5-0.70.70.40.3-0.5-0.50.4-0.60.2-0.9-0.50.9
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.5-0.2-0.30.30.30.3-0.30.30.3-0.30.3-0.30.40.2-0.3-0.30.40.30.4-0.4-0.40.4-0.40.40.30.4-0.3
Delta time to tail flick, test, before/after SA0.00.10.10.30.30.3-0.3-0.3-0.30.3-0.3-0.30.3-0.30.3-0.2-0.30.30.2-0.2-0.20.00.20.2-0.20.2-0.1-0.2-0.10.0
Tibia length2.46.68.5-2.4-2.9-2.42.52.52.5-2.52.52.5-2.52.7-2.82.32.8-2.8-1.52.92.82.6-2.7-2.72.5-2.82.52.32.7-2.3
Ambulatory time before self-admin0.10.21.10.2-0.10.1-0.00.00.0-0.00.10.1-0.10.4-0.40.50.4-0.40.30.40.40.6-0.7-0.70.5-1.11.0-0.40.2-0.6
Ambulatory time after self-admin0.00.10.3-0.3-0.2-0.20.20.20.2-0.20.20.2-0.20.2-0.20.40.2-0.2-0.20.30.20.6-0.4-0.30.2-0.30.4-0.00.2-0.5
Bone: tissue strength0.20.20.9-0.10.30.1-0.2-0.2-0.10.2-0.2-0.20.2-0.30.4-0.1-0.40.4-0.4-0.3-0.4-0.40.30.3-0.30.5-0.1-1.0-0.80.9
Total heroin consumption0.60.71.5-0.4-0.7-0.70.80.80.8-0.80.80.8-0.80.9-0.90.80.9-0.9-0.30.90.90.9-1.1-1.01.2-1.11.10.20.8-0.7
Bone: trabecular number0.20.40.9-0.9-0.3-0.90.80.80.9-0.80.80.8-0.80.4-0.40.80.3-0.4-0.90.50.40.5-0.5-0.50.5-0.20.9-0.7-0.50.6
Bone: trabecular spacing0.00.00.20.3-0.10.3-0.2-0.2-0.20.2-0.2-0.20.10.1-0.1-0.20.1-0.10.20.10.1-0.1-0.1-0.1-0.1-0.3-0.1-0.5-0.20.4
Bone: trabecular thickness0.00.00.2-0.2-0.4-0.10.10.10.1-0.10.10.1-0.10.1-0.1-0.10.2-0.20.00.20.30.0-0.20.00.50.1-0.40.50.1-0.4
Bone: trabecular tissue density9.917.422.8-4.8-4.8-4.64.64.64.6-4.64.64.6-4.54.5-4.54.34.5-4.5-4.44.44.44.3-4.4-4.24.3-3.82.70.91.4-0.5
Water consumed over 24 hours0.10.10.70.2-0.10.2-0.1-0.1-0.20.1-0.1-0.10.10.1-0.20.00.2-0.20.40.20.20.3-0.2-0.20.3-0.50.00.80.7-0.7
Number of responses in last shaping day0.10.20.6-0.4-0.8-0.20.30.30.2-0.30.30.2-0.20.4-0.5-0.10.5-0.5-0.00.50.60.2-0.5-0.20.6-0.2-0.10.60.4-0.4