Nfia

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative polyA NM_012988.2 0.03 0.03 2.0e-03 0.01 0.01 0.01 0.01 8.8e-03 8.9e-03 2.3e-02 2.2e-02
2 NAcc alternative polyA XM_039109300.1 0.03 0.03 3.3e-03 0.01 0.01 0.01 0.01 1.6e-02 1.5e-02 3.9e-02 4.5e-02
3 NAcc alternative polyA XM_039109300.1 0.02 0.02 3.5e-03 0 0.01 0 0 1.6e-01 1.2e-02 9.5e-02 1.0e-01
4 PL alternative TSS XM_039109303.1 0.02 0.02 9.6e-03 0.01 0.02 0.01 0.01 3.1e-02 4.7e-03 1.5e-02 2.0e-02
5 Liver alternative TSS XM_039109303.1 0.12 0.08 2.8e-13 0.08 0.08 0.08 0.08 3.5e-09 2.3e-09 4.3e-09 3.7e-09
6 Liver alternative polyA XM_039109300.1 0.02 0.03 9.2e-03 0 0.01 -0 0 1.1e-01 2.7e-02 6.6e-01 7.6e-02
7 pVTA alternative polyA NM_012988.2 0.12 0.12 1.0e-03 0.03 0.04 0.03 0.03 2.6e-02 8.5e-03 1.8e-02 2.9e-02
8 pVTA alternative polyA XM_039109300.1 0.09 0.09 4.3e-03 0.02 0.03 0.02 0.02 4.7e-02 2.2e-02 3.5e-02 4.7e-02
9 BLA alternative TSS XM_039109303.1 0.06 0.07 6.4e-03 0.03 0.03 0.01 0.03 7.6e-03 7.3e-03 9.1e-02 9.7e-03
10 NAcc alternative TSS XM_039109303.1 0.03 0.03 1.1e-03 0.02 0.03 0.03 0.02 7.3e-04 6.3e-04 6.1e-04 7.7e-04
11 Brain mRNA stability Nfia 0.08 0.1 9.0e-03 0.02 0.02 0.01 0.01 8.8e-03 1.1e-02 2.4e-02 1.8e-02
12 BLA mRNA stability Nfia 0.07 0.06 5.2e-04 0.07 0.06 0.07 0.07 9.7e-05 2.2e-04 2.1e-04 1.2e-04
13 Adipose gene expression Nfia 0.39 0.21 1.8e-08 0.05 0.05 0.05 0.05 1.1e-06 4.4e-06 2.2e-06 2.6e-06
14 Liver alternative TSS NM_012988.2 0.03 0.03 3.8e-03 0.01 0 -0 0 5.4e-02 1.7e-01 4.7e-01 9.9e-02
15 Brain alternative polyA NM_012988.2 0.03 0.02 5.6e-03 0.03 0.02 0.02 0.02 1.9e-03 1.1e-02 2.8e-03 3.7e-03
16 Brain alternative polyA XM_039109300.1 0.03 0.02 5.7e-03 0.02 0.01 0.02 0.02 2.4e-03 1.3e-02 3.5e-03 5.8e-03
17 Brain alternative polyA NM_012988.2 0.03 0.02 4.9e-03 0.02 0.02 0.02 0.02 2.5e-03 1.0e-02 3.6e-03 6.3e-03
18 Brain alternative polyA XM_039109300.1 0.03 0.02 4.8e-03 0.02 0.02 0.02 0.02 2.4e-03 1.0e-02 6.6e-03 5.6e-03
19 Brain isoform ratio NM_012988.2 0.03 0.03 2.2e-03 0.04 0.03 0.04 0.04 1.1e-04 1.3e-03 3.0e-04 2.9e-04
20 PL mRNA stability Nfia 0.03 0.03 1.9e-03 0.02 0.02 0.01 0.02 1.1e-03 1.5e-03 2.4e-02 1.4e-03
21 pVTA alternative polyA NM_012988.2 0.08 0.09 6.0e-03 0.02 0.01 0.01 0.01 4.8e-02 1.1e-01 7.1e-02 1.0e-01
22 pVTA alternative polyA XM_039109300.1 0.08 0.09 7.4e-03 0.02 0.01 0.01 0.01 5.7e-02 1.2e-01 1.4e-01 1.1e-01
23 Eye alternative polyA XM_039109300.1 0.91 0.07 3.6e-03 0.03 0.07 0.04 0.01 1.1e-01 3.1e-02 9.5e-02 2.0e-01
24 Eye alternative polyA NM_012988.2 0.89 0.09 5.4e-03 0.03 0.07 0.03 0.01 1.2e-01 3.5e-02 1.3e-01 2.2e-01
25 Eye alternative polyA XM_039109300.1 0.95 0.04 1.8e-03 0.02 0.07 0.03 0 1.4e-01 3.2e-02 1.1e-01 2.7e-01
26 Eye alternative polyA NM_012988.2 0.94 0.05 3.0e-03 0.02 0.06 0.02 -0 1.9e-01 4.0e-02 1.4e-01 3.6e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.20.31.6-1.3-0.6-0.6-0.6-0.6-0.50.5-0.5-0.40.30.60.60.4-0.5-0.30.3-0.30.3-0.30.3-0.50.50.4-0.40.5-0.5
Area under the delay curve1.01.12.7-1.6-1.2-1.2-1.2-1.2-1.21.2-1.2-1.11.21.21.21.1-0.8-0.90.9-0.90.9-0.90.9-0.90.9-0.50.6-0.40.4
BMI with tail0.20.72.21.50.80.80.80.90.8-0.70.70.7-0.6-1.2-1.0-0.51.31.0-1.01.0-1.01.0-1.00.6-0.6-0.10.0-0.10.2
BMI without tail0.40.91.80.70.80.80.80.90.9-0.80.80.8-0.9-1.0-1.1-0.71.31.1-1.11.1-1.11.1-1.10.6-0.60.8-0.80.8-0.8
Body weight0.10.20.5-0.4-0.6-0.6-0.6-0.5-0.60.6-0.6-0.60.60.20.50.7-0.3-0.30.3-0.30.3-0.30.3-0.70.7-0.30.3-0.30.3
Weight adjusted by age1.92.13.00.91.61.61.61.61.6-1.61.61.7-1.6-1.6-1.6-1.71.31.1-1.11.1-1.11.1-1.11.6-1.61.6-1.51.5-1.5
Bone surface1.72.93.61.21.81.81.81.81.8-1.81.91.9-1.9-1.7-1.8-1.71.51.9-1.91.9-1.91.9-1.91.9-1.91.1-1.11.0-1.0
Bone volume0.61.01.20.30.90.90.91.01.0-1.01.01.0-1.1-0.9-1.0-0.90.91.1-1.11.1-1.11.1-1.11.0-1.01.0-0.90.9-0.9
Breakpoint value in progressive ratio session1.82.05.0-0.2-1.3-1.3-1.3-1.3-1.31.3-1.3-1.51.41.21.21.5-1.1-1.11.1-1.11.1-1.11.1-0.70.7-2.22.2-2.22.2
Number of licking bursts0.10.10.70.3-0.1-0.1-0.0-0.1-0.10.1-0.1-0.10.20.20.00.20.10.1-0.10.1-0.10.1-0.10.2-0.2-0.80.8-0.80.8
Context. condit. distance diff. score1.92.33.2-1.4-1.7-1.7-1.7-1.7-1.71.7-1.7-1.71.61.71.61.7-1.6-1.51.5-1.51.5-1.51.5-1.81.8-0.70.6-0.50.5
Locomotion velocity, session 10.10.10.6-0.80.00.00.10.00.1-0.10.10.2-0.10.3-0.2-0.2-0.00.0-0.00.0-0.00.0-0.00.4-0.40.6-0.60.7-0.7
Locomotion distance, session 10.91.21.8-1.3-1.1-1.1-1.1-1.1-1.11.1-1.1-1.11.11.21.11.1-1.2-1.31.3-1.31.3-1.31.3-0.90.9-0.40.5-0.30.3
Locomotion velocity, session 20.40.50.80.00.50.60.60.60.6-0.50.60.6-0.6-0.7-0.7-0.60.80.7-0.70.7-0.70.7-0.70.6-0.60.9-0.90.9-0.9
Locomotion distance, session 20.00.00.1-0.10.10.10.10.10.1-0.10.10.1-0.1-0.2-0.2-0.10.0-0.10.1-0.10.1-0.10.10.3-0.30.1-0.00.1-0.1
Locomotion velocity, session 30.10.10.3-0.5-0.2-0.2-0.2-0.2-0.20.1-0.1-0.10.10.30.30.1-0.5-0.30.3-0.30.3-0.30.30.0-0.0-0.10.1-0.10.1
Locomotion distance, session 30.00.00.20.40.10.10.10.20.1-0.10.10.1-0.1-0.2-0.2-0.00.00.1-0.10.1-0.10.1-0.1-0.00.00.2-0.20.2-0.2
Stereotopy head waving bouts, day 31.31.63.4-0.0-0.9-0.9-0.9-0.9-0.90.9-0.9-1.11.10.70.81.1-1.4-1.61.6-1.61.6-1.61.6-0.70.7-1.81.8-1.81.8
Stereotopy head waving duration, day 31.01.21.9-0.5-0.9-1.0-1.0-1.0-1.01.0-1.0-1.11.00.80.91.0-1.3-1.41.4-1.41.4-1.41.4-1.01.0-1.11.1-1.11.1
Locomotion velocity, session 70.70.81.3-0.6-0.9-0.9-0.9-0.9-0.90.8-0.9-0.90.91.11.01.0-1.0-0.70.7-0.70.7-0.70.7-0.60.6-1.01.0-1.01.0
Locomotion distance, session 70.20.20.5-0.6-0.5-0.5-0.5-0.5-0.50.5-0.5-0.50.40.70.60.5-0.5-0.40.4-0.40.4-0.40.4-0.60.60.3-0.30.3-0.3
Stereotopy head waving bouts, day 71.01.13.41.81.21.21.21.21.2-1.21.11.0-1.0-1.1-1.1-0.90.81.0-1.01.0-1.01.0-1.01.1-1.1-0.40.3-0.50.5
Stereotopy head waving duration, day 70.60.71.51.21.01.00.90.90.9-1.01.00.8-0.8-0.9-0.8-0.80.50.7-0.70.7-0.70.7-0.71.1-1.1-0.50.5-0.60.6
Locomotion velocity, session 80.40.51.4-1.2-0.8-0.8-0.8-0.8-0.80.7-0.7-0.70.61.20.80.8-0.9-0.60.6-0.60.6-0.60.6-0.70.7-0.00.00.1-0.1
Locomotion distance, session 80.71.12.1-1.5-1.2-1.2-1.2-1.2-1.21.2-1.2-1.11.11.21.01.1-1.2-1.01.0-1.01.0-1.01.0-1.11.10.1-0.10.2-0.2
Degree of sensitization distance0.00.00.10.10.20.20.20.10.2-0.20.20.2-0.2-0.0-0.1-0.30.10.1-0.10.1-0.10.1-0.10.2-0.2-0.00.0-0.00.0
Degree of sensitization stereotypy1.21.31.81.31.31.31.31.31.3-1.31.31.2-1.2-1.1-1.1-1.10.91.3-1.31.3-1.31.3-1.31.2-1.20.4-0.40.3-0.3
Conditioned locomotion0.10.11.61.30.10.10.10.10.10.0-0.1-0.10.2-0.7-0.60.10.2-0.10.1-0.10.1-0.10.1-0.20.2-0.40.4-0.50.5
Cocaine response after cond. corrected0.50.61.31.10.80.80.80.70.7-0.80.70.6-0.6-0.8-0.6-0.70.80.7-0.70.7-0.70.7-0.70.9-0.9-0.50.5-0.60.6
Cocaine response after cond. not corrected0.40.40.80.80.60.60.60.50.5-0.60.60.5-0.5-0.6-0.3-0.50.60.6-0.60.6-0.60.6-0.60.9-0.9-0.70.7-0.80.8
Cocaine response before conditioning0.10.10.3-0.4-0.2-0.2-0.2-0.3-0.20.1-0.1-0.20.10.50.50.1-0.3-0.20.2-0.20.2-0.20.20.1-0.1-0.40.4-0.40.4
Saline control response0.30.42.00.20.10.10.10.20.2-0.00.00.2-0.1-0.3-0.4-0.10.60.5-0.50.5-0.50.5-0.5-0.60.61.4-1.41.4-1.4
Bone: connectivity density1.52.33.20.81.61.61.61.61.6-1.71.71.7-1.8-1.5-1.5-1.71.31.6-1.61.6-1.61.6-1.61.6-1.61.2-1.11.1-1.1
Bone: cortical apparent density6.58.611.6-3.4-3.3-3.3-3.3-3.3-3.33.3-3.3-3.23.23.23.13.1-3.0-3.03.0-3.03.0-3.03.0-3.13.1-1.11.1-0.80.8
Bone: cortical area0.10.10.30.20.40.40.40.40.4-0.40.40.4-0.5-0.5-0.5-0.50.30.2-0.20.2-0.20.2-0.20.2-0.20.5-0.50.5-0.5
Bone: cortical porosity0.40.40.90.90.80.80.80.80.8-0.70.70.7-0.7-0.8-0.9-0.70.50.5-0.50.5-0.50.5-0.50.6-0.60.4-0.40.3-0.3
Bone: cortical porosity0.70.71.41.21.01.01.01.01.0-0.90.90.9-1.0-1.0-1.1-0.90.60.8-0.80.8-0.80.8-0.80.7-0.70.5-0.60.5-0.5
Bone: cortical thickness0.20.40.6-0.5-0.6-0.6-0.6-0.6-0.60.6-0.6-0.60.50.50.60.5-0.7-0.80.8-0.80.8-0.80.8-0.80.8-0.30.3-0.30.3
Bone: cortical thickness0.00.00.10.40.20.20.20.20.2-0.20.20.2-0.3-0.1-0.2-0.3-0.1-0.10.1-0.10.1-0.10.1-0.00.0-0.00.0-0.10.1
Bone: cortical tissue density6.28.111.3-3.4-3.3-3.3-3.2-3.2-3.23.2-3.2-3.13.13.13.03.0-2.9-2.92.9-2.92.9-2.92.9-3.13.1-1.01.0-0.70.7
Condit. Reinf. active minus inactive responses0.00.00.1-0.3-0.2-0.2-0.2-0.2-0.20.2-0.2-0.20.20.00.20.0-0.1-0.20.2-0.20.2-0.20.20.0-0.0-0.30.3-0.20.2
Condit. Reinf. active-inactive response ratio0.10.10.10.1-0.2-0.2-0.2-0.2-0.20.3-0.3-0.30.3-0.30.10.2-0.1-0.30.3-0.30.3-0.30.3-0.30.3-0.30.3-0.30.3
Condit. Reinf. active responses0.10.10.3-0.60.10.20.20.10.2-0.20.20.3-0.3-0.2-0.0-0.40.20.2-0.20.2-0.20.2-0.20.4-0.40.5-0.40.5-0.5
Condit. Reinf. inactive responses0.40.52.2-0.60.30.30.40.40.4-0.40.40.5-0.6-0.2-0.3-0.50.30.6-0.60.6-0.60.6-0.60.4-0.41.4-1.41.5-1.5
Incentive salience index mean0.00.00.0-0.2-0.0-0.0-0.0-0.1-0.00.0-0.0-0.00.0-0.10.1-0.00.10.1-0.10.1-0.10.1-0.10.1-0.1-0.10.1-0.10.1
Condit. Reinf. lever presses0.10.10.3-0.3-0.5-0.5-0.5-0.5-0.50.5-0.5-0.50.40.40.50.5-0.2-0.10.1-0.10.1-0.10.1-0.50.5-0.10.1-0.10.0
Condit. Reinf. active minus inactive responses1.01.23.8-2.0-1.2-1.2-1.2-1.2-1.21.2-1.1-1.11.01.01.20.8-1.2-1.11.1-1.11.1-1.11.1-1.21.20.4-0.30.5-0.5
Condit. Reinf. active-inactive response ratio0.30.31.4-1.2-0.5-0.5-0.5-0.5-0.50.5-0.4-0.40.30.30.40.2-0.4-0.50.5-0.50.5-0.50.5-0.70.70.8-0.80.9-0.9
Condit. Reinf. active responses1.11.53.9-2.0-1.3-1.3-1.3-1.3-1.31.3-1.2-1.21.21.31.30.9-1.5-1.41.4-1.41.4-1.41.4-1.21.2-0.10.2-0.0-0.0
Condit. Reinf. inactive responses2.22.74.0-2.0-1.8-1.8-1.8-1.8-1.81.7-1.7-1.71.72.01.81.6-1.9-1.81.8-1.81.8-1.81.8-1.51.5-0.80.8-0.70.7
Condit. Reinf. lever presses2.02.74.01.31.81.81.81.81.8-1.81.91.8-1.7-1.6-1.7-2.01.71.7-1.71.7-1.71.7-1.72.0-2.00.8-0.70.7-0.6
Condit. Reinf. lever reinforcers received0.60.83.5-1.9-1.0-0.9-0.9-1.0-0.90.9-0.8-0.80.81.11.00.5-1.0-1.01.0-1.01.0-1.01.0-0.70.70.2-0.10.3-0.3
Conditioned reinforcement - actives0.40.40.9-0.9-0.8-0.8-0.8-0.8-0.80.8-0.8-0.70.80.80.70.7-0.7-0.60.6-0.60.6-0.60.6-0.60.6-0.10.1-0.10.1
Conditioned reinforcement - inactives1.51.72.5-1.5-1.4-1.4-1.4-1.3-1.41.4-1.4-1.31.41.01.11.3-1.4-1.61.6-1.61.6-1.61.6-1.31.3-0.20.2-0.00.0
Conditioned locomotion0.10.10.3-0.1-0.3-0.3-0.3-0.2-0.30.5-0.5-0.30.50.0-0.10.50.10.1-0.10.1-0.10.1-0.1-0.50.50.3-0.40.4-0.4
Patch foraging indifference point 0 sec5.48.712.93.23.33.33.33.43.3-3.13.23.3-3.1-3.6-3.5-3.13.02.7-2.72.7-2.72.7-2.72.9-2.92.1-2.11.9-1.9
Patch foraging indifference point AUC0.60.71.20.10.60.60.60.60.6-0.60.60.7-0.7-0.5-0.7-0.71.11.1-1.11.1-1.11.1-1.10.7-0.70.8-0.80.8-0.8
Delay disc. indifference point, 0s delay1.92.14.7-2.2-1.7-1.7-1.7-1.6-1.61.6-1.6-1.61.51.51.51.6-1.5-1.41.4-1.41.4-1.41.4-1.61.6-0.20.3-0.10.1
Delay disc. indifference point, 16s delay0.10.10.40.20.30.30.30.20.3-0.30.30.2-0.2-0.2-0.3-0.30.60.5-0.50.5-0.50.5-0.50.6-0.6-0.30.3-0.30.3
Delay disc. indifference point, 2s delay0.80.92.2-0.7-0.9-0.9-0.9-1.0-0.90.8-0.9-1.00.90.90.90.8-0.9-0.80.8-0.80.8-0.80.8-0.50.5-1.51.5-1.41.4
Delay disc. indifference point, 24s delay0.30.20.6-0.8-0.6-0.6-0.6-0.6-0.60.6-0.6-0.60.60.70.70.5-0.2-0.30.3-0.30.3-0.30.3-0.40.4-0.30.3-0.20.2
Delay disc. indifference point, 4s delay3.23.44.4-2.0-2.1-2.1-2.1-2.1-2.12.1-2.1-2.12.11.91.92.1-1.8-1.81.8-1.81.8-1.81.8-2.02.0-0.80.8-0.60.6
Delay disc. indifference point, 8s delay2.42.54.7-2.2-1.8-1.8-1.7-1.7-1.71.8-1.7-1.61.71.61.61.7-1.5-1.71.7-1.71.7-1.71.7-1.61.6-0.40.4-0.20.2
Indifference point function ln k0.10.10.40.4-0.1-0.2-0.2-0.1-0.20.2-0.2-0.30.3-0.10.10.3-0.4-0.40.4-0.40.4-0.40.4-0.30.3-0.60.5-0.60.6
Indifference point function log k0.10.10.40.4-0.1-0.2-0.2-0.1-0.20.2-0.2-0.30.3-0.10.10.3-0.4-0.40.4-0.40.4-0.40.4-0.30.3-0.60.5-0.60.6
Patch foraging total patch changes 0 sec4.67.410.92.93.13.13.13.13.1-2.92.93.1-2.9-3.3-3.3-2.92.72.4-2.42.4-2.42.4-2.42.7-2.72.0-2.01.8-1.8
Patch foraging total patch changes 12 sec0.60.71.30.90.90.90.91.00.9-0.80.80.9-0.8-1.1-1.1-0.70.80.8-0.80.8-0.80.8-0.80.8-0.80.8-0.80.8-0.7
Patch foraging total patch changes 18 sec2.02.53.61.11.51.41.51.51.5-1.41.41.5-1.6-1.4-1.6-1.41.91.9-1.91.9-1.91.9-1.91.2-1.21.6-1.61.6-1.5
Patch foraging total patch changes 24 sec0.91.12.11.41.21.21.21.21.2-1.11.11.2-1.1-1.3-1.4-1.11.20.9-0.90.9-0.90.9-0.91.3-1.30.4-0.40.3-0.3
Patch foraging total patch changes 6 sec2.23.34.71.21.71.71.71.81.7-1.61.61.8-1.6-2.0-2.0-1.62.22.0-2.02.0-2.02.0-2.01.5-1.51.9-1.91.9-1.8
Patch foraging time to switch 0 sec2.23.36.8-2.6-2.1-2.0-2.1-2.1-2.01.9-1.9-1.91.72.52.51.9-1.9-1.71.7-1.71.7-1.71.7-1.61.6-0.91.0-0.70.7
Patch foraging water rate 0 sec1.72.88.32.91.91.91.91.91.8-1.71.71.7-1.4-2.2-2.3-1.51.81.6-1.61.6-1.61.6-1.61.5-1.50.4-0.40.2-0.2
Patch foraging water rate 12 sec3.45.112.63.52.62.62.52.52.5-2.52.42.3-2.2-2.8-2.7-2.32.52.2-2.22.2-2.22.2-2.22.1-2.10.3-0.40.1-0.0
Patch foraging water rate 18 sec0.30.53.71.90.70.70.70.70.6-0.60.50.4-0.3-0.8-0.9-0.40.40.2-0.20.2-0.20.2-0.20.4-0.4-0.80.8-0.90.9
Patch foraging water rate 24 sec0.10.21.41.20.10.10.10.10.1-0.10.0-0.10.2-0.3-0.40.1-0.1-0.10.1-0.10.1-0.10.1-0.10.1-0.80.8-0.90.9
Patch foraging water rate 6 sec0.30.52.41.50.80.80.80.90.8-0.70.70.7-0.5-0.9-1.1-0.50.70.6-0.60.6-0.60.6-0.60.6-0.60.1-0.20.1-0.1
Seeking ratio, delayed vs. immediate footshock0.70.84.00.7-0.3-0.3-0.4-0.4-0.40.3-0.3-0.50.50.60.60.2-0.8-0.60.6-0.60.6-0.60.6-0.30.3-1.91.9-2.02.0
Distance traveled before self-admin0.40.41.90.7-0.4-0.4-0.4-0.5-0.50.4-0.4-0.60.30.60.60.6-0.4-0.30.3-0.30.3-0.30.3-0.30.3-1.31.3-1.41.4
Distance traveled after self-admin0.10.10.3-0.3-0.3-0.3-0.3-0.3-0.30.3-0.3-0.30.20.30.30.4-0.3-0.30.3-0.30.3-0.30.30.2-0.2-0.50.5-0.50.5
Extensor digitorum longus weight0.52.02.7-1.0-1.6-1.6-1.6-1.6-1.61.6-1.6-1.61.61.61.61.6-1.3-1.11.1-1.11.1-1.11.1-1.61.6-1.21.2-1.21.2
Bone: elastic displacement0.50.61.7-1.3-0.9-0.9-0.9-0.9-0.80.8-0.8-0.80.71.11.00.6-1.0-0.80.8-0.80.8-0.80.8-0.80.80.1-0.00.1-0.1
Bone: elastic work0.91.12.6-1.6-1.2-1.2-1.2-1.2-1.21.2-1.2-1.11.01.31.21.0-1.1-1.11.1-1.11.1-1.11.1-1.31.30.1-0.10.2-0.2
Bone: endosteal estimation0.51.11.61.21.21.21.21.21.2-1.21.21.1-1.2-1.2-1.2-1.01.11.1-1.11.1-1.11.1-1.11.1-1.10.4-0.40.3-0.3
Bone: endosteal perimeter1.02.12.81.21.61.61.61.61.6-1.51.61.6-1.6-1.6-1.7-1.51.51.5-1.51.5-1.51.5-1.51.6-1.61.0-1.00.9-0.9
Epididymis fat weight1.84.36.4-2.5-2.5-2.5-2.5-2.4-2.52.5-2.5-2.42.42.22.32.4-1.7-1.81.8-1.81.8-1.81.8-2.32.3-0.80.8-0.60.6
Delta time in closed arm before/after self-admin0.30.30.60.80.60.60.60.60.6-0.60.60.6-0.6-0.8-0.8-0.70.50.3-0.30.3-0.30.3-0.30.5-0.50.1-0.10.0-0.0
Delta time in open arm before/after self-admin0.50.50.90.30.80.80.80.80.8-0.90.90.8-0.8-0.4-0.4-0.90.40.6-0.60.6-0.60.6-0.61.0-1.00.3-0.30.3-0.3
Diff in mean of infusions in LGA sessions0.80.91.6-0.2-0.9-0.9-0.9-1.0-0.90.9-1.0-1.01.00.80.80.9-0.9-1.01.0-1.01.0-1.01.0-0.80.8-1.21.2-1.21.2
Delay discount exponential model param1.01.12.81.71.31.21.21.31.2-1.21.21.2-1.2-1.2-1.2-1.10.90.9-0.90.9-0.90.9-0.90.9-0.90.5-0.60.4-0.4
Extinction: sum of active levers before priming0.90.92.70.1-0.7-0.7-0.8-0.8-0.80.7-0.8-0.90.80.80.81.0-0.8-0.80.8-0.80.8-0.80.8-0.70.7-1.61.6-1.61.6
Active lever presses in extinction session 60.10.10.50.6-0.2-0.2-0.2-0.2-0.20.3-0.3-0.30.3-0.0-0.00.4-0.1-0.10.1-0.10.1-0.10.1-0.30.3-0.70.6-0.70.7
Bone: final force0.30.40.8-0.3-0.7-0.7-0.7-0.7-0.70.7-0.8-0.80.70.60.70.9-0.6-0.50.5-0.50.5-0.50.5-0.80.8-0.60.6-0.60.6
Bone: final moment0.00.00.00.2-0.0-0.0-0.0-0.0-0.00.0-0.1-0.1-0.00.00.00.10.10.2-0.20.2-0.20.2-0.2-0.20.2-0.20.1-0.20.2
Food consumed during 24 hour testing period0.40.51.00.0-0.7-0.7-0.6-0.6-0.70.8-0.8-0.80.90.50.31.0-0.4-0.60.6-0.60.6-0.60.6-0.50.5-1.01.0-1.01.0
Glucose0.81.24.20.30.70.70.80.80.8-0.70.70.9-0.8-0.7-1.0-0.90.91.0-1.01.0-1.01.0-1.00.1-0.12.0-2.12.0-2.0
Heart weight1.52.13.6-1.5-1.6-1.7-1.6-1.6-1.61.7-1.7-1.61.61.11.31.7-1.4-1.51.5-1.51.5-1.51.5-1.91.90.0-0.10.2-0.2
Delay discount hyperbolic model param1.21.32.71.71.31.31.31.31.3-1.31.31.3-1.3-1.3-1.3-1.21.01.0-1.01.0-1.01.0-1.00.9-0.90.7-0.80.6-0.6
Intermittent access intake day 1-15 change2.12.17.8-2.8-1.6-1.6-1.6-1.6-1.51.5-1.5-1.41.41.71.71.0-1.6-1.61.6-1.61.6-1.61.6-1.01.0-0.10.20.0-0.0
Intermittent access intake escalation2.12.18.0-2.8-1.6-1.6-1.6-1.6-1.51.5-1.4-1.41.41.71.71.0-1.6-1.51.5-1.51.5-1.51.5-0.90.9-0.30.4-0.10.1
Intermittent access intake escalation 21.71.76.7-2.6-1.4-1.4-1.4-1.4-1.31.3-1.3-1.21.21.21.20.9-1.5-1.51.5-1.51.5-1.51.5-0.90.9-0.10.20.1-0.1
Intermitt. access day 1 inactive lever presses1.41.52.11.01.41.41.41.31.4-1.41.41.4-1.4-1.2-1.2-1.41.31.2-1.21.2-1.21.2-1.21.2-1.20.9-0.90.8-0.8
Intermitt. access day 15 inactive lever presses0.60.71.6-0.6-0.8-0.8-0.8-0.8-0.80.9-0.9-0.80.80.60.70.8-0.8-0.90.9-0.90.9-0.90.9-1.31.30.0-0.10.1-0.1
Intermitt. access escalation Index2.52.23.01.01.51.51.51.51.5-1.41.51.5-1.5-1.4-1.4-1.31.61.7-1.71.7-1.71.7-1.71.5-1.51.2-1.21.1-1.1
Intermittent access day 1 total infusions0.20.21.30.30.0-0.00.00.10.00.1-0.10.00.2-0.3-0.30.20.30.3-0.30.3-0.30.3-0.3-0.40.41.1-1.11.1-1.1
Intermittent access day 15 total infusions0.70.83.1-1.8-1.0-0.9-0.9-0.9-0.91.0-0.9-0.80.90.80.80.6-0.9-0.80.8-0.80.8-0.80.8-0.70.70.6-0.60.7-0.7
Intermittent access terminal intake (last 3 days)0.30.41.6-1.3-0.6-0.6-0.5-0.5-0.50.6-0.6-0.50.60.20.30.4-0.4-0.60.6-0.60.6-0.60.6-0.40.40.7-0.70.8-0.8
Intermittent access total infusions0.20.20.9-0.6-0.4-0.4-0.3-0.3-0.30.5-0.5-0.30.50.10.10.3-0.3-0.40.4-0.40.4-0.40.4-0.40.40.8-0.90.9-0.9
Intermittent access day 1 locomotion1.21.22.90.70.90.90.91.00.9-0.70.70.9-0.7-1.2-1.2-0.71.21.2-1.21.2-1.21.2-1.20.5-0.51.7-1.71.6-1.6
Intermittent access day 15 total locomotion0.50.52.1-0.60.20.20.30.30.3-0.10.10.4-0.1-0.8-0.7-0.20.80.7-0.70.7-0.70.7-0.70.2-0.21.4-1.41.4-1.4
Intermittent access total locomotion0.60.61.8-0.00.50.50.60.60.6-0.40.50.6-0.4-0.9-0.8-0.50.90.8-0.80.8-0.80.8-0.80.5-0.51.3-1.31.3-1.3
Intermittent access standard deviation1.31.43.2-1.8-1.1-1.1-1.1-1.1-1.11.1-1.1-1.01.10.91.01.0-1.3-1.51.5-1.51.5-1.51.5-1.01.00.3-0.30.4-0.5
Left kidney weight0.61.83.3-0.4-1.2-1.2-1.2-1.3-1.21.3-1.3-1.41.50.91.11.3-1.3-1.41.4-1.41.4-1.41.4-1.01.0-1.81.8-1.81.8
Right kidney weight0.82.35.6-0.1-1.1-1.1-1.1-1.2-1.21.1-1.2-1.31.41.01.31.2-1.7-1.71.7-1.71.7-1.71.7-0.90.9-2.32.3-2.42.4
Cocaine induced anxiety0.00.00.1-0.3-0.0-0.0-0.1-0.1-0.1-0.00.0-0.0-0.10.10.10.1-0.1-0.20.2-0.20.2-0.20.20.0-0.0-0.20.2-0.20.2
Post-drug Anxiety1.31.42.1-0.8-1.1-1.1-1.1-1.2-1.11.0-1.0-1.11.01.31.31.1-1.2-1.31.3-1.31.3-1.31.3-0.90.9-1.41.5-1.41.4
Baseline Anxiety0.50.61.1-0.1-0.7-0.7-0.7-0.7-0.70.7-0.7-0.80.80.70.70.6-0.7-0.70.7-0.70.7-0.70.7-0.60.6-1.01.0-1.01.0
Tail length0.92.97.5-2.7-1.9-1.9-1.9-1.9-1.81.8-1.8-1.71.62.01.81.6-1.8-1.71.7-1.71.7-1.71.7-1.71.7-0.10.10.1-0.1
Length with tail0.72.64.7-2.2-1.7-1.7-1.7-1.7-1.71.7-1.7-1.61.61.71.71.5-2.1-1.81.8-1.81.8-1.81.8-1.71.7-0.40.4-0.20.2
Length without tail0.10.31.1-0.2-0.4-0.4-0.5-0.5-0.50.4-0.4-0.50.50.30.70.4-1.0-0.70.7-0.70.7-0.70.7-0.50.5-0.60.6-0.60.6
Times rat made contact with spout0.00.00.20.20.20.20.20.20.2-0.10.10.1-0.0-0.5-0.4-0.20.30.2-0.20.2-0.20.2-0.20.1-0.10.1-0.10.1-0.1
Lifetime Intake0.20.21.4-0.4-0.1-0.1-0.1-0.0-0.10.2-0.2-0.00.3-0.1-0.10.1-0.1-0.10.1-0.10.1-0.10.1-0.30.31.1-1.11.2-1.2
Liver weight, left1.22.03.8-1.4-1.6-1.6-1.6-1.5-1.61.7-1.6-1.51.51.31.21.6-1.1-1.41.4-1.41.4-1.41.4-2.02.00.3-0.30.4-0.5
Liver weight, right5.38.811.3-2.4-3.3-3.3-3.3-3.2-3.33.3-3.3-3.33.33.13.23.2-2.9-3.13.1-3.13.1-3.13.1-3.43.4-1.51.5-1.31.3
Locomotor activity0.10.10.20.20.20.20.10.20.2-0.10.10.1-0.2-0.3-0.1-0.1-0.3-0.50.5-0.50.5-0.50.5-0.20.20.4-0.40.4-0.4
Locomotor testing distance0.91.63.11.81.61.61.61.61.6-1.61.51.5-1.4-1.6-1.5-1.50.90.8-0.80.8-0.80.8-0.81.5-1.50.3-0.40.2-0.2
Locomotor testing rearing0.20.20.8-0.3-0.2-0.2-0.2-0.2-0.20.3-0.3-0.30.3-0.00.00.2-0.7-0.90.9-0.90.9-0.90.9-0.30.3-0.00.00.0-0.0
Locomotion in novel chamber0.70.91.90.71.01.11.11.01.1-1.11.11.0-1.0-0.9-0.9-1.20.80.8-0.80.8-0.80.8-0.81.4-1.40.00.0-0.00.1
Locomotion in novel chamber post-restriction0.10.10.20.40.30.20.20.30.2-0.20.20.3-0.4-0.3-0.2-0.2-0.3-0.10.1-0.10.1-0.10.1-0.00.00.4-0.50.4-0.4
Fecal boli incidents, locomotor time 10.10.10.7-0.50.10.10.10.10.1-0.10.10.2-0.1-0.2-0.1-0.30.10.1-0.10.1-0.10.1-0.1-0.10.10.8-0.80.8-0.8
Change in fecal boli incidents, locomotor task0.20.10.30.0-0.4-0.4-0.4-0.4-0.40.4-0.4-0.40.50.40.40.4-0.5-0.40.4-0.40.4-0.40.4-0.40.4-0.40.3-0.30.3
Time >=10cm from walls, locomotor time 10.10.10.20.30.20.20.20.20.2-0.30.30.2-0.3-0.2-0.2-0.4-0.0-0.00.0-0.00.0-0.00.00.2-0.2-0.30.3-0.40.4
Bouts of movement, locomotor time 10.20.20.30.20.40.40.40.40.4-0.30.30.4-0.4-0.6-0.6-0.20.50.4-0.40.4-0.40.4-0.40.1-0.10.5-0.60.5-0.5
Total resting periods, locomotor time 10.10.10.30.20.40.40.40.40.4-0.30.30.4-0.4-0.6-0.6-0.20.50.4-0.40.4-0.40.4-0.40.1-0.10.4-0.40.4-0.4
Rest time, locomotor task time 10.00.00.1-0.00.10.10.10.10.1-0.10.10.1-0.1-0.1-0.10.00.30.1-0.10.1-0.10.1-0.10.0-0.00.1-0.10.1-0.1
Distance moved, locomotor task time 10.00.00.2-0.3-0.1-0.1-0.2-0.2-0.20.1-0.1-0.1-0.00.40.30.1-0.4-0.20.2-0.20.2-0.20.20.1-0.1-0.20.3-0.20.2
Vertical activity count, locomotor time 10.20.20.40.40.50.50.40.40.4-0.50.50.4-0.6-0.2-0.3-0.20.50.6-0.60.6-0.60.6-0.60.6-0.6-0.10.1-0.10.2
Time >=10cm from walls, locomotor time 22.62.73.4-0.8-1.5-1.5-1.6-1.6-1.61.5-1.5-1.71.51.71.71.4-1.8-1.91.9-1.91.9-1.91.9-1.51.5-1.81.8-1.81.8
Bouts of movement, locomotor time 20.91.02.01.21.11.11.11.11.1-1.01.01.1-1.0-1.3-1.4-1.01.00.8-0.80.8-0.80.8-0.80.7-0.70.7-0.70.6-0.6
Total resting periods, locomotor time 21.01.12.21.21.21.11.21.21.2-1.11.11.1-1.0-1.4-1.5-1.11.10.9-0.90.9-0.90.9-0.90.8-0.80.8-0.80.7-0.7
Rest time, locomotor task time 20.70.81.4-0.00.80.80.80.80.8-0.70.80.9-0.7-0.8-0.8-0.81.11.0-1.01.0-1.01.0-1.00.9-0.91.2-1.11.2-1.2
Distance moved, locomotor task time 21.31.62.4-0.7-1.1-1.1-1.1-1.2-1.11.0-1.0-1.21.01.21.21.2-1.4-1.41.4-1.41.4-1.41.4-0.80.8-1.51.5-1.51.5
Vertical activity count, locomotor time 20.30.30.80.2-0.4-0.4-0.4-0.4-0.50.4-0.4-0.50.30.50.40.6-0.6-0.60.6-0.60.6-0.60.6-0.40.4-0.90.9-0.90.9
Light reinforcement 10.50.91.9-1.4-1.0-1.0-1.0-0.9-0.91.0-1.0-0.80.90.80.80.9-1.1-1.11.1-1.11.1-1.11.1-1.11.10.5-0.50.7-0.7
Light reinforcement 20.20.20.7-0.9-0.6-0.6-0.6-0.5-0.60.6-0.6-0.50.50.40.30.6-0.2-0.40.4-0.40.4-0.40.4-0.50.50.2-0.20.3-0.3
Bone: marrow area0.51.11.51.21.21.11.11.21.1-1.11.11.1-1.1-1.1-1.1-1.01.11.1-1.11.1-1.11.1-1.11.0-1.00.4-0.40.3-0.3
Bone: maximum diameter0.71.22.41.21.11.11.11.21.1-1.01.01.1-1.0-1.6-1.5-0.91.31.1-1.11.1-1.11.1-1.10.8-0.81.0-1.00.9-0.9
Bone: maximum force0.10.10.3-0.0-0.3-0.3-0.4-0.3-0.30.4-0.4-0.40.20.20.30.5-0.2-0.30.3-0.30.3-0.30.3-0.60.6-0.30.3-0.30.3
Bone: maximum moment0.10.10.30.60.40.40.40.40.4-0.40.40.4-0.5-0.4-0.4-0.30.40.4-0.40.4-0.40.4-0.40.1-0.10.1-0.10.1-0.1
Mean time between licks in bursts5.47.611.9-3.2-3.2-3.2-3.2-3.2-3.23.2-3.2-3.13.13.43.13.0-2.7-2.52.5-2.52.5-2.52.5-3.03.0-1.11.1-0.90.9
Mean num. licks in bursts0.20.20.9-0.20.30.30.30.30.3-0.30.30.4-0.4-0.7-0.4-0.40.30.1-0.10.1-0.10.1-0.10.0-0.01.0-1.01.0-1.0
Cd content in liver1.71.92.91.71.51.41.41.51.4-1.41.41.4-1.3-1.6-1.6-1.31.71.6-1.61.6-1.61.6-1.61.1-1.10.7-0.80.6-0.6
Co content in liver0.20.31.30.7-0.2-0.2-0.2-0.2-0.20.2-0.2-0.40.3-0.10.40.4-0.4-0.40.4-0.40.4-0.40.4-0.40.4-1.11.0-1.11.1
Cu content in liver0.30.30.60.2-0.6-0.6-0.6-0.6-0.60.6-0.6-0.70.70.50.60.6-0.8-0.40.4-0.40.4-0.40.4-0.70.7-0.80.7-0.80.8
Fe content in liver0.81.01.31.01.11.11.11.11.1-1.01.11.1-1.1-1.0-1.1-1.10.91.0-1.01.0-1.01.0-1.00.9-0.90.9-0.90.8-0.8
K content in liver1.01.01.8-0.9-1.1-1.1-1.1-1.1-1.11.0-1.0-1.01.11.31.11.1-1.2-1.11.1-1.11.1-1.11.1-0.80.8-0.70.7-0.60.6
Mg content in liver0.20.20.70.20.50.50.50.50.5-0.60.60.6-0.5-0.3-0.4-0.60.20.5-0.50.5-0.50.5-0.50.8-0.80.1-0.10.1-0.1
Mn content in liver0.10.10.8-0.4-0.4-0.4-0.4-0.4-0.40.4-0.4-0.40.40.90.40.4-0.2-0.20.2-0.20.2-0.20.2-0.10.1-0.40.5-0.40.4
Na content in liver3.33.55.8-2.4-2.1-2.1-2.1-2.1-2.12.1-2.1-2.02.02.12.21.9-1.9-1.91.9-1.91.9-1.91.9-1.81.8-0.91.0-0.80.8
Rb content in liver1.11.43.5-1.1-1.0-1.0-1.1-1.1-1.10.9-0.9-1.01.01.21.41.0-1.9-1.51.5-1.51.5-1.51.5-0.80.8-0.90.9-0.80.8
Se content in liver1.11.32.81.71.21.21.21.11.1-1.11.11.1-1.1-1.0-1.2-1.11.41.4-1.41.4-1.41.4-1.41.2-1.2-0.10.1-0.20.2
Sr content in liver0.10.10.30.40.30.30.30.30.3-0.20.20.3-0.2-0.4-0.4-0.20.50.1-0.10.1-0.10.1-0.10.2-0.20.0-0.10.0-0.0
Zn content in liver1.41.52.41.31.21.21.21.21.2-1.21.21.2-1.2-1.3-1.3-1.11.41.6-1.61.6-1.61.6-1.61.0-1.00.8-0.80.7-0.7
Bone: minimum diameter0.91.72.81.01.51.51.51.51.5-1.61.61.5-1.7-1.2-1.3-1.61.11.2-1.21.2-1.21.2-1.21.5-1.50.8-0.80.7-0.7
Time in familiar zone, hab. session 13.02.83.7-0.4-1.5-1.5-1.6-1.6-1.61.6-1.6-1.71.71.51.51.6-1.9-1.91.9-1.91.9-1.91.9-1.61.6-1.81.7-1.71.7
Time in novel zone, hab. session 15.65.57.51.82.52.62.62.52.6-2.62.62.6-2.6-2.3-2.4-2.62.52.4-2.42.4-2.42.4-2.42.7-2.71.3-1.31.2-1.2
Total zone transitions, hab. session 12.43.45.3-1.3-1.8-1.8-1.8-1.8-1.81.7-1.8-1.81.71.51.71.9-2.1-2.32.3-2.32.3-2.32.3-1.61.6-1.51.5-1.41.4
Total locomotion distance, hab. session 10.30.51.1-0.2-0.5-0.5-0.5-0.5-0.50.5-0.5-0.60.60.20.50.7-0.6-0.80.8-0.80.8-0.80.8-0.30.3-1.01.0-1.01.0
Locomotion velocity, hab. session 10.30.40.6-0.7-0.6-0.6-0.6-0.6-0.60.6-0.6-0.60.70.30.50.7-0.6-0.80.8-0.80.8-0.80.8-0.40.4-0.60.6-0.50.5
Time in familiar zone, hab. session 20.60.61.0-0.2-0.7-0.8-0.8-0.8-0.80.7-0.7-0.80.80.80.80.8-1.0-0.80.8-0.80.8-0.80.8-0.80.8-0.90.8-0.80.8
Time in novel zone, hab. session 20.80.81.30.51.01.01.01.01.0-1.01.01.0-1.0-1.1-1.0-1.11.00.8-0.80.8-0.80.8-0.81.1-1.10.6-0.60.6-0.6
Total zone transitions, hab. session 25.26.88.1-2.4-2.8-2.8-2.8-2.8-2.82.8-2.8-2.82.82.62.62.7-2.8-2.82.8-2.82.8-2.82.8-2.42.4-1.81.9-1.71.7
Total locomotion distance, hab. session 22.53.34.1-1.6-1.9-1.9-1.9-1.9-1.91.9-1.9-1.92.01.71.81.9-1.8-2.02.0-2.02.0-2.02.0-1.51.5-1.51.6-1.41.4
Locomotion velocity, hab. session 22.12.93.6-1.5-1.8-1.8-1.8-1.8-1.81.8-1.8-1.81.91.61.61.8-1.6-1.91.9-1.91.9-1.91.9-1.41.4-1.41.4-1.31.3
Novel to familiar place preference ratio1.71.83.11.51.41.41.41.41.4-1.31.31.3-1.1-1.8-1.5-1.41.71.5-1.51.5-1.51.5-1.51.1-1.10.6-0.60.4-0.4
Novelty place preference1.21.22.31.31.11.11.21.21.2-1.11.11.1-0.9-1.5-1.3-1.21.41.3-1.31.3-1.31.3-1.31.0-1.00.5-0.50.4-0.4
Time in novel zone, NPP test1.61.72.81.51.41.41.41.41.4-1.31.31.3-1.2-1.7-1.5-1.51.61.4-1.41.4-1.41.4-1.41.2-1.20.5-0.50.3-0.3
Total zone transitions, NPP test1.62.33.1-1.3-1.7-1.7-1.7-1.7-1.71.7-1.7-1.71.71.31.61.8-1.6-1.61.6-1.61.6-1.61.6-1.61.6-1.00.9-0.90.8
Total locomotion distance, NPP test0.20.30.7-0.2-0.6-0.6-0.6-0.6-0.60.6-0.6-0.70.70.10.50.7-0.4-0.40.4-0.40.4-0.40.4-0.40.4-0.80.8-0.80.8
Locomotion velocity, NPP test0.40.60.9-0.4-0.8-0.8-0.8-0.8-0.80.9-0.9-0.90.90.40.70.9-0.6-0.70.7-0.70.7-0.70.7-0.70.7-0.90.9-0.90.9
Intraocular pressure0.20.31.31.10.50.50.50.50.5-0.50.50.5-0.6-0.6-0.6-0.40.90.6-0.60.6-0.60.6-0.60.2-0.20.1-0.20.0-0.0
Delta distance traveled before/after self-admin0.50.61.5-0.30.60.60.60.60.6-0.60.60.7-0.7-0.6-0.6-0.50.60.7-0.70.7-0.70.7-0.70.8-0.81.2-1.21.2-1.2
Delta ambulatory time before/after self-admin0.30.41.4-0.50.30.40.40.40.4-0.30.40.5-0.4-0.5-0.5-0.20.50.5-0.50.5-0.50.5-0.50.5-0.51.1-1.11.2-1.2
Parametrial fat weight4.38.410.73.03.23.23.23.23.2-3.33.33.2-3.2-2.9-2.9-3.23.03.0-3.03.0-3.03.0-3.03.1-3.11.2-1.21.0-0.9
Pavlov. Cond. lever latency0.40.51.6-1.3-0.7-0.7-0.7-0.7-0.70.7-0.7-0.60.60.80.70.5-0.9-0.90.9-0.90.9-0.90.9-0.60.60.1-0.10.2-0.2
Pavlov. Cond. magazine entry latency0.50.71.0-0.9-0.9-0.9-0.9-0.9-0.90.9-0.9-0.90.90.91.00.8-1.0-0.90.9-0.90.9-0.90.9-0.90.9-0.30.3-0.20.2
Pavlov. Cond. change in total contacts0.30.40.50.60.70.70.70.70.7-0.70.70.7-0.7-0.6-0.6-0.70.50.6-0.60.6-0.60.6-0.60.6-0.60.5-0.50.5-0.5
Pavlov. Cond. index score0.00.00.10.20.10.10.10.10.1-0.10.10.1-0.0-0.1-0.1-0.00.20.2-0.20.2-0.20.2-0.2-0.00.00.1-0.20.1-0.1
Pavlov. Cond. latency score0.10.10.30.60.30.20.20.30.3-0.20.20.2-0.1-0.4-0.3-0.10.40.4-0.40.4-0.40.4-0.40.1-0.10.1-0.10.0-0.0
Pavlov. Cond. lever contacts0.10.10.30.50.20.20.20.20.2-0.10.10.1-0.1-0.3-0.30.00.50.4-0.40.4-0.40.4-0.40.1-0.10.0-0.10.0-0.0
Pavlov. Cond. magazine entry number0.50.61.00.90.90.90.90.80.9-0.90.90.9-0.9-0.9-0.9-0.90.80.7-0.70.7-0.70.7-0.71.0-1.0-0.00.0-0.10.1
Pavlov. Cond. intertrial magazine entries0.70.82.8-1.7-1.0-1.0-1.0-1.0-1.01.0-1.0-0.90.91.11.00.9-1.0-0.90.9-0.90.9-0.90.9-0.90.90.3-0.30.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.10.10.10.10.10.1-0.10.10.1-0.1-0.1-0.1-0.00.10.3-0.30.3-0.30.3-0.3-0.00.00.3-0.30.2-0.2
Pavlov. Cond. response bias0.20.20.5-0.5-0.6-0.6-0.6-0.5-0.60.6-0.6-0.60.60.70.60.6-0.5-0.40.4-0.40.4-0.40.4-0.60.6-0.10.1-0.00.0
Pavlov. Cond. lever latency1.21.62.2-0.8-1.3-1.3-1.3-1.3-1.31.3-1.3-1.41.41.11.21.5-1.5-1.31.3-1.31.3-1.31.3-1.21.2-1.01.0-0.90.9
Pavlov. Cond. magazine entry latency1.31.52.00.51.31.31.31.31.3-1.31.31.4-1.4-1.1-1.0-1.41.21.2-1.21.2-1.21.2-1.21.2-1.21.2-1.11.1-1.1
Pavlov. Cond. change in total contacts1.41.93.01.01.51.51.51.51.5-1.61.61.6-1.5-1.1-1.3-1.71.61.4-1.41.4-1.41.4-1.41.7-1.70.7-0.70.6-0.6
Pavlov. Cond. index score1.21.62.40.71.31.31.31.31.4-1.41.41.4-1.4-1.0-1.1-1.61.31.2-1.21.2-1.21.2-1.21.4-1.40.9-0.90.9-0.9
Pavlov. Cond. latency score1.01.21.90.61.21.21.21.21.2-1.21.21.2-1.2-1.0-1.0-1.41.21.1-1.11.1-1.11.1-1.11.2-1.20.8-0.70.7-0.7
Pavlov. Cond. lever contacts1.82.43.11.31.71.71.71.71.7-1.71.71.7-1.7-1.4-1.5-1.71.71.7-1.71.7-1.71.7-1.71.7-1.70.8-0.80.7-0.7
Pavlov. Cond. magazine entry number0.40.50.8-0.0-0.7-0.7-0.7-0.7-0.70.7-0.7-0.80.80.50.40.9-0.6-0.60.6-0.60.6-0.60.6-0.60.6-0.90.9-0.90.9
Pavlov. Cond. intertrial magazine entries1.62.25.0-2.2-1.6-1.5-1.5-1.6-1.51.5-1.4-1.41.31.71.61.2-2.0-1.71.7-1.71.7-1.71.7-1.31.3-0.30.3-0.20.1
Pavlov. Cond. lever-magazine prob. diff.1.11.52.30.61.31.31.31.31.3-1.41.41.4-1.4-1.0-1.1-1.51.31.2-1.21.2-1.21.2-1.21.4-1.41.0-0.90.9-0.9
Pavlov. Cond. response bias1.31.82.50.71.41.41.41.41.4-1.51.51.5-1.5-1.0-1.1-1.61.41.4-1.41.4-1.41.4-1.41.5-1.51.0-1.00.9-0.9
Time in closed arm before self-admin0.00.00.1-0.2-0.2-0.2-0.2-0.2-0.20.2-0.2-0.20.20.20.20.4-0.10.2-0.20.2-0.20.2-0.20.0-0.00.2-0.20.3-0.3
Time in closed arm after self-admin0.30.30.91.00.50.50.50.50.5-0.50.50.5-0.4-0.6-0.6-0.40.60.7-0.70.7-0.70.7-0.70.6-0.6-0.20.2-0.30.3
Time in open arm before self-admin0.00.00.10.1-0.1-0.1-0.1-0.1-0.10.2-0.2-0.20.2-0.1-0.10.10.2-0.10.1-0.10.1-0.10.1-0.30.3-0.20.2-0.20.2
Time in open arm after self-admin0.91.01.50.71.11.11.11.11.1-1.11.11.1-1.0-1.0-1.0-1.21.01.0-1.01.0-1.01.0-1.01.1-1.10.5-0.50.4-0.4
Bone: periosteal estimation0.51.01.51.11.21.11.11.11.1-1.11.11.1-1.2-1.2-1.2-1.11.01.0-1.01.0-1.01.0-1.01.0-1.00.5-0.50.4-0.4
Bone: periosteal perimeter0.40.71.20.30.90.90.90.90.9-0.90.91.0-1.0-0.9-1.0-0.90.70.6-0.60.6-0.60.6-0.60.8-0.81.1-1.11.0-1.0
Bone: post-yield work1.31.84.72.21.51.51.51.51.5-1.51.51.4-1.4-1.5-1.4-1.31.51.3-1.31.3-1.31.3-1.31.4-1.4-0.30.2-0.40.4
Progressive ratio test 1 active lever presses2.42.55.0-1.7-1.7-1.7-1.7-1.6-1.71.9-1.8-1.61.81.21.31.8-1.4-1.51.5-1.51.5-1.51.5-2.22.20.8-0.81.0-1.0
Progressive ratio test 1 breakpoint3.43.66.5-2.0-2.1-2.1-2.1-1.9-2.02.2-2.2-2.02.11.61.72.2-1.8-1.91.9-1.91.9-1.91.9-2.52.50.6-0.60.7-0.8
Progressive ratio test 1 inactive lever presses1.51.63.3-1.8-1.3-1.3-1.3-1.2-1.21.4-1.4-1.11.30.90.91.2-1.0-1.21.2-1.21.2-1.21.2-1.71.71.1-1.11.3-1.3
Progressive ratio test 2 active lever presses0.40.41.3-1.1-0.6-0.6-0.5-0.4-0.50.7-0.6-0.40.60.10.10.5-0.3-0.30.3-0.30.3-0.30.3-0.60.61.0-1.01.1-1.1
Progressive ratio test 2 breakpoint0.30.41.2-1.0-0.6-0.6-0.5-0.4-0.50.7-0.6-0.40.60.10.10.5-0.2-0.30.3-0.30.3-0.30.3-0.70.71.0-1.01.1-1.1
Progressive ratio test 2 inactive lever presses0.70.83.5-1.4-0.6-0.6-0.5-0.4-0.50.7-0.7-0.40.6-0.0-0.10.60.1-0.10.1-0.10.1-0.10.1-0.80.81.7-1.71.9-1.9
Incentive Sensitization - Responses0.50.51.6-0.30.30.40.40.50.4-0.30.30.5-0.3-0.9-0.9-0.40.70.7-0.70.7-0.70.7-0.70.4-0.41.2-1.21.2-1.2
Incentive Sensitization - Breakpoint0.40.51.4-0.30.40.40.40.50.4-0.30.30.5-0.3-0.9-0.9-0.40.70.6-0.60.6-0.60.6-0.60.5-0.51.1-1.11.2-1.2
Sum of active levers in priming session hrs 5-63.73.65.3-0.6-1.8-1.8-1.8-1.9-1.91.8-1.9-2.01.91.71.72.0-1.8-1.91.9-1.91.9-1.91.9-1.71.7-2.32.3-2.32.2
Progressive ratio0.70.81.7-1.3-0.9-0.9-0.9-0.9-0.90.9-0.9-0.81.10.80.80.6-0.9-1.21.2-1.21.2-1.21.2-0.50.5-0.30.3-0.20.2
Food seeking constrained by brief footshock3.23.95.1-2.0-2.2-2.2-2.2-2.2-2.22.2-2.2-2.22.12.22.22.1-2.0-1.91.9-1.91.9-1.91.9-2.12.1-1.11.1-1.01.0
Seeking ratio, punishment vs. effort0.30.30.7-0.2-0.6-0.6-0.7-0.6-0.70.6-0.6-0.70.40.70.70.9-0.6-0.30.3-0.30.3-0.30.3-0.90.9-0.40.4-0.40.4
Retroperitoneal fat weight0.20.71.3-0.4-0.9-0.9-0.9-0.9-0.91.0-1.0-1.01.20.90.91.0-0.7-0.90.9-0.90.9-0.90.9-0.80.8-0.60.6-0.60.5
Reaction time number correct0.00.00.10.2-0.0-0.0-0.0-0.0-0.00.1-0.1-0.00.1-0.2-0.10.1-0.1-0.40.4-0.40.4-0.40.4-0.20.20.0-0.10.0-0.0
Reaction time mean minus median0.10.10.3-0.4-0.00.00.0-0.1-0.0-0.10.10.0-0.10.40.4-0.20.10.2-0.20.2-0.20.2-0.20.5-0.5-0.50.5-0.50.5
Reaction time mean minus median AUC0.10.20.6-0.5-0.3-0.3-0.3-0.4-0.30.2-0.3-0.30.30.60.60.2-0.3-0.30.3-0.30.3-0.30.30.1-0.1-0.80.8-0.70.8
Reaction time num false alarms0.30.52.2-0.90.30.40.40.40.4-0.30.40.6-0.5-0.7-0.7-0.60.40.0-0.00.0-0.00.0-0.00.5-0.51.4-1.31.5-1.5
Reaction time num false alarms AUC0.81.13.9-0.60.80.80.80.80.8-0.80.81.0-0.9-1.0-1.1-1.00.60.3-0.30.3-0.30.3-0.30.8-0.81.9-1.92.0-2.0
Reaction time trials correct on left0.00.00.10.2-0.0-0.0-0.0-0.0-0.00.1-0.1-0.00.1-0.2-0.10.1-0.1-0.40.4-0.40.4-0.40.4-0.20.20.0-0.10.0-0.0
Reaction time trials on left0.00.00.10.30.10.10.10.10.1-0.00.00.00.0-0.3-0.2-0.0-0.0-0.30.3-0.30.3-0.30.3-0.20.20.1-0.10.1-0.1
Reaction time mean0.50.71.30.50.80.80.80.70.8-0.90.90.8-0.9-0.4-0.3-1.00.91.1-1.11.1-1.11.1-1.11.1-1.1-0.30.3-0.30.3
Reaction time mean AUC0.20.30.60.40.40.40.40.30.4-0.50.50.4-0.5-0.00.1-0.60.40.6-0.60.6-0.60.6-0.60.8-0.8-0.60.6-0.60.6
Median of all reaction times0.81.01.70.81.01.01.01.01.0-1.11.11.0-1.1-0.7-0.5-1.11.11.3-1.31.3-1.31.3-1.31.2-1.2-0.10.1-0.10.1
Reaction time omissions1.62.23.50.91.41.31.41.41.4-1.31.31.4-1.4-1.6-1.5-1.41.51.6-1.61.6-1.61.6-1.60.9-0.91.9-1.91.8-1.8
Reaction time false alarm rate0.81.23.1-0.40.90.91.01.01.0-1.01.01.1-1.1-1.0-1.1-1.10.80.7-0.70.7-0.70.7-0.71.1-1.11.7-1.71.7-1.7
Reaction time premature initiation rate0.30.40.7-0.7-0.8-0.8-0.8-0.8-0.80.7-0.8-0.80.60.70.80.8-0.5-0.60.6-0.60.6-0.60.6-0.80.8-0.40.4-0.40.4
Reaction time premature initiations0.60.81.2-0.7-0.9-1.0-1.0-1.0-1.00.9-1.0-1.00.90.81.01.0-0.8-0.90.9-0.90.9-0.90.9-1.11.1-0.50.5-0.50.5
Std. dev. reaction times0.81.12.40.61.01.11.11.01.0-1.21.21.1-1.1-0.6-0.6-1.21.21.3-1.31.3-1.31.3-1.31.6-1.6-0.20.3-0.30.3
Reaction time trials completed0.00.00.10.30.10.10.10.10.1-0.00.00.00.0-0.3-0.2-0.0-0.0-0.30.3-0.30.3-0.30.3-0.20.20.1-0.10.1-0.1
Reaction time trials AUC0.00.00.10.20.10.10.10.10.1-0.00.00.00.0-0.3-0.1-0.0-0.0-0.30.3-0.30.3-0.30.3-0.10.10.1-0.10.1-0.1
Run reversals in cocaine runway, females0.30.31.5-0.00.20.20.20.30.2-0.10.20.3-0.2-0.4-0.4-0.10.40.2-0.20.2-0.20.2-0.2-0.00.01.2-1.21.2-1.2
Run reversals in cocaine runway, males0.20.20.30.10.50.50.40.40.5-0.50.50.5-0.5-0.2-0.2-0.50.40.5-0.50.5-0.50.5-0.50.5-0.50.1-0.10.1-0.1
Latency to leave start box in cocaine runway0.30.30.80.2-0.3-0.4-0.4-0.4-0.40.3-0.4-0.50.30.40.40.4-0.9-0.80.8-0.80.8-0.80.8-0.60.6-0.70.7-0.70.7
Latency to leave start box in cocaine runway, F0.20.20.4-0.2-0.3-0.3-0.3-0.3-0.30.2-0.2-0.30.20.40.40.2-0.7-0.60.6-0.60.6-0.60.6-0.30.3-0.50.5-0.50.5
Latency to leave start box in cocaine runway, M0.20.20.80.0-0.3-0.3-0.3-0.3-0.30.3-0.3-0.30.20.30.30.4-0.9-0.70.7-0.70.7-0.70.7-0.50.5-0.20.1-0.10.1
Std. dev. time between licks in bursts0.00.00.1-0.1-0.1-0.1-0.1-0.1-0.10.0-0.0-0.1-0.00.20.10.10.10.4-0.40.4-0.40.4-0.40.0-0.0-0.10.1-0.10.1
Total sessions with >9 infusions1.01.12.1-1.2-1.2-1.2-1.1-1.0-1.11.3-1.3-1.11.30.80.91.2-0.9-1.01.0-1.01.0-1.01.0-1.51.50.5-0.50.6-0.6
Short access day 1 total inactive lever presses0.30.41.00.20.40.40.40.50.5-0.40.40.5-0.4-0.6-0.6-0.50.70.6-0.60.6-0.60.6-0.60.2-0.21.0-1.01.0-1.0
Short access day 10 total inactive lever presses1.41.52.40.81.41.41.41.41.4-1.51.51.4-1.5-1.5-1.5-1.51.21.1-1.11.1-1.11.1-1.11.6-1.60.5-0.50.4-0.4
Short access day 1 total infusions0.10.10.7-0.30.10.10.20.20.2-0.10.10.2-0.1-0.2-0.2-0.3-0.00.0-0.00.0-0.00.0-0.00.1-0.10.8-0.80.9-0.9
Short access day 10 total infusions0.20.31.30.1-0.2-0.2-0.2-0.1-0.20.4-0.4-0.20.4-0.2-0.10.5-0.1-0.10.1-0.10.1-0.10.1-0.80.81.1-1.11.1-1.1
Short access total infusions0.20.31.6-0.00.10.10.20.20.2-0.00.00.2-0.0-0.3-0.3-0.10.20.2-0.20.2-0.20.2-0.2-0.20.21.2-1.21.2-1.3
Short access day 1 locomotion0.80.82.2-0.00.70.70.70.70.7-0.60.60.8-0.7-0.9-0.9-0.80.91.0-1.01.0-1.01.0-1.00.5-0.51.5-1.51.5-1.5
Short access day 10 total locomotion0.70.81.30.60.80.80.80.90.8-0.70.70.9-0.7-1.0-1.0-0.70.91.0-1.01.0-1.01.0-1.00.6-0.61.1-1.11.1-1.1
Short access total locomotion0.30.31.5-0.3-0.0-0.00.00.10.00.2-0.20.00.2-0.4-0.40.20.40.3-0.30.3-0.30.3-0.3-0.30.31.2-1.21.2-1.2
One hour access (0.3 mA shock)0.10.10.7-0.8-0.3-0.3-0.2-0.2-0.20.3-0.3-0.20.30.20.20.1-0.4-0.50.5-0.50.5-0.50.5-0.20.20.3-0.30.3-0.3
Compulsive drug intake5.15.28.32.32.72.72.72.72.7-2.82.82.7-2.9-2.2-2.3-2.61.92.0-2.02.0-2.02.0-2.02.5-2.51.2-1.21.1-1.0
One hour access (shock baseline)2.42.84.6-2.1-2.0-2.0-1.9-1.9-1.92.1-2.0-1.92.11.41.51.9-1.6-1.61.6-1.61.6-1.61.6-1.81.8-0.30.3-0.10.1
Social response proportion1.51.62.60.31.21.21.21.31.3-1.31.31.4-1.4-1.1-1.2-1.20.91.2-1.21.2-1.21.2-1.21.2-1.21.6-1.61.6-1.6
Social responses0.60.82.7-1.2-0.4-0.4-0.5-0.4-0.40.5-0.4-0.30.20.20.30.3-0.9-0.80.8-0.80.8-0.80.8-0.90.91.5-1.51.6-1.6
Social time1.01.37.1-0.50.50.50.50.60.6-0.50.50.8-0.6-0.6-0.8-0.80.60.5-0.50.5-0.50.5-0.50.0-0.02.6-2.62.7-2.7
Soleus weight0.30.81.6-1.3-0.9-0.9-0.9-1.0-0.90.8-0.8-0.90.81.21.10.7-0.9-0.90.9-0.90.9-0.90.9-0.50.5-0.91.0-0.90.9
Bone: stiffness0.10.20.40.2-0.4-0.4-0.4-0.4-0.40.5-0.5-0.50.40.10.20.6-0.3-0.50.5-0.50.5-0.50.5-0.60.6-0.40.4-0.40.4
Tibialis anterior weight7.024.028.85.25.45.45.45.35.3-5.35.35.2-5.1-5.4-5.1-5.25.25.3-5.35.3-5.35.3-5.35.1-5.12.1-2.11.7-1.7
Time to tail flick, vehicle, before self-admin0.91.01.41.11.11.11.11.11.1-1.11.11.1-1.1-1.2-1.2-1.11.01.0-1.01.0-1.01.0-1.00.9-0.90.6-0.60.5-0.5
Time to tail flick, vehicle, after self-admin1.21.32.01.11.21.21.21.21.2-1.21.21.2-1.3-1.1-1.1-1.21.21.2-1.21.2-1.21.2-1.21.4-1.40.4-0.40.3-0.3
Time to tail flick, test, before self-admin0.40.41.10.30.60.60.50.60.6-0.50.50.6-0.5-0.8-0.8-0.50.50.5-0.50.5-0.50.5-0.50.4-0.41.0-1.01.0-1.0
Time to tail flick, test, after self-admin0.10.10.20.40.20.20.20.30.2-0.20.20.2-0.1-0.3-0.3-0.00.30.5-0.50.5-0.50.5-0.50.2-0.20.1-0.10.1-0.1
Delta time to tail flick, vehicle, before/after SA0.30.30.9-0.2-0.4-0.4-0.4-0.4-0.40.3-0.4-0.40.30.50.50.5-0.4-0.40.4-0.40.4-0.40.4-0.00.0-0.90.9-0.90.9
Delta time to tail flick, test, before/after SA0.20.20.30.50.30.30.40.30.3-0.40.30.3-0.4-0.2-0.2-0.20.40.4-0.40.4-0.40.4-0.40.5-0.5-0.30.3-0.40.4
Tibia length1.95.57.3-1.5-2.5-2.5-2.5-2.5-2.52.6-2.7-2.62.72.12.22.7-2.2-2.52.5-2.52.5-2.52.5-2.62.6-1.41.4-1.31.3
Ambulatory time before self-admin1.01.03.00.5-0.7-0.7-0.8-0.8-0.80.7-0.7-0.90.81.01.00.8-0.9-0.90.9-0.90.9-0.90.9-0.60.6-1.71.6-1.71.7
Ambulatory time after self-admin0.10.10.60.1-0.2-0.2-0.2-0.2-0.20.1-0.1-0.20.00.30.30.3-0.2-0.20.2-0.20.2-0.20.20.2-0.2-0.80.8-0.80.8
Bone: tissue strength0.20.20.50.10.50.60.50.50.5-0.60.60.6-0.6-0.2-0.4-0.60.40.5-0.50.5-0.50.5-0.50.7-0.70.2-0.20.2-0.2
Total heroin consumption1.21.52.4-0.6-1.2-1.2-1.2-1.2-1.21.2-1.2-1.31.21.21.21.2-1.2-1.21.2-1.21.2-1.21.2-0.80.8-1.51.5-1.51.5
Bone: trabecular number0.10.11.0-1.0-0.4-0.3-0.4-0.4-0.30.3-0.2-0.20.10.50.50.2-0.5-0.20.2-0.20.2-0.20.2-0.30.30.3-0.20.3-0.3
Bone: trabecular spacing0.10.10.80.7-0.0-0.0-0.1-0.1-0.10.1-0.1-0.20.20.00.10.10.2-0.00.0-0.00.0-0.00.0-0.10.1-0.90.8-0.90.9
Bone: trabecular thickness0.20.21.10.00.00.00.10.10.10.1-0.00.1-0.0-0.3-0.50.10.40.3-0.30.3-0.30.3-0.3-0.20.21.0-1.01.0-1.0
Bone: trabecular tissue density12.717.923.9-4.9-4.8-4.8-4.8-4.8-4.84.9-4.8-4.74.74.44.54.7-4.2-4.24.2-4.24.2-4.24.2-4.74.7-1.41.4-1.01.0
Water consumed over 24 hours0.20.31.11.00.40.40.40.40.3-0.30.30.2-0.2-0.4-0.5-0.20.60.5-0.50.5-0.50.5-0.50.4-0.4-0.70.7-0.80.8
Number of responses in last shaping day0.20.20.7-0.2-0.5-0.5-0.5-0.4-0.50.7-0.7-0.50.70.20.20.70.20.2-0.20.2-0.20.2-0.2-0.80.80.3-0.30.3-0.3